$168+ Cheap flights from Myrtle Beach to Santa Ana, CA (MYR - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SNA
May 29 — Jun 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Santa Ana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to Santa AnaExplore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Myrtle Beach to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:41 am
MYR
- SNA
2 stops11h 43m
Delta
Tue 6/232:00 pm
SNA
- MYR
1 stop6h 59m
Delta
Deal found 4/25![Delta logo]()
$430
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:25 am
MYR
- SNA
2 stops13h 28m
United Airlines
Sat 9/197:00 pm
SNA
- MYR
2 stops10h 58m
United Airlines
Deal found 4/24![United Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:07 pm
MYR
- SNA
1 stop9h 22m
Delta
Fri 5/2912:25 pm
SNA
- MYR
1 stop8h 33m
Delta
Deal found 4/28![Delta logo]()
$436
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:15 pm
MYR
- SNA
1 stop6h 46m
American Airlines
Sat 9/197:58 am
SNA
- MYR
1 stop8h 08m
American Airlines
Deal found 4/24![American Airlines logo]()
$450
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
MYR
- SNA
1 stop9h 40m
Delta
Wed 6/246:45 am
SNA
- MYR
1 stop9h 22m
Delta
Deal found 4/25![Delta logo]()
$451
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
MYR
- SNA
2 stops11h 49m
American Airlines
Sat 5/2312:01 pm
SNA
- MYR
1 stop9h 09m
American Airlines
Deal found 4/25![American Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:21 pm
MYR
- SNA
1 stop8h 13m
Delta
Tue 6/22:00 pm
SNA
- MYR
1 stop6h 58m
Delta
Deal found 4/27![Delta logo]()
$461
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:17 pm
MYR
- SNA
2 stops21h 15m
Delta
Tue 6/232:00 pm
SNA
- MYR
1 stop6h 59m
Delta
Deal found 4/28![Delta logo]()
$465
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:41 am
MYR
- SNA
2 stops11h 43m
Delta
Mon 6/222:00 pm
SNA
- MYR
1 stop6h 59m
Delta
Deal found 4/25![Delta logo]()
$472
Best flights from Myrtle Beach to Santa AnaDiscover carefully curated flight deals from Myrtle Beach to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Myrtle Beach to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:07 pm
MYR
- SNA
1 stop9h 22m
Delta
Fri 5/2912:25 pm
SNA
- MYR
1 stop8h 33m
Delta
Deal found 4/28![Delta logo]()
$436
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:34 am
MYR
- SNA
2 stops14h 27m
United Airlines
Tue 6/26:26 pm
SNA
- MYR
2 stops12h 33m
United Airlines
Deal found 4/27![United Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:21 pm
MYR
- SNA
1 stop8h 13m
Delta
Tue 6/22:00 pm
SNA
- MYR
1 stop6h 58m
Delta
Deal found 4/26![Delta logo]()
$461
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:41 am
MYR
- SNA
2 stops11h 43m
Delta
Mon 6/222:00 pm
SNA
- MYR
1 stop6h 59m
Delta
Deal found 4/25![Delta logo]()
$472
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:14 pm
MYR
- SNA
1 stop10h 21m
United Airlines
Sat 5/166:39 pm
SNA
- MYR
2 stops13h 03m
United Airlines
Deal found 4/28![United Airlines logo]()
$592
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 pm
MYR
- SNA
2 stops18h 17m
Delta
Wed 6/246:45 am
SNA
- MYR
1 stop9h 22m
Delta
Deal found 4/25![Delta logo]()
$512
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:21 pm
MYR
- SNA
1 stop8h 56m
Delta
Sun 5/172:00 pm
SNA
- MYR
1 stop6h 58m
Delta
Deal found 4/26![Delta logo]()
$563
Last-minute flights from Myrtle Beach to Santa AnaDiscover last-minute flight deals from Myrtle Beach to Santa Ana. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Santa Ana. Data last updated April 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:57 pm
MYR
- SNA
1 stop10h 17m
American Airlines
Sat 5/166:45 am
SNA
- MYR
2 stops12h 37m
American Airlines
Deal found 4/24![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
MYR
- SNA
2 stops11h 49m
American Airlines
Sat 5/2312:01 pm
SNA
- MYR
1 stop9h 09m
American Airlines
Deal found 4/25![American Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:30 pm
MYR
- SNA
2 stops10h 04m
Delta
Tue 6/22:00 pm
SNA
- MYR
1 stop6h 58m
Delta
Deal found 4/29![Delta logo]()
$430
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:07 pm
MYR
- SNA
1 stop9h 22m
Delta
Fri 5/2912:25 pm
SNA
- MYR
1 stop8h 33m
Delta
Deal found 4/28![Delta logo]()
$436
One-way flights from Myrtle Beach to Santa AnaSearch for one-way flight options from Myrtle Beach to Santa Ana. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Myrtle Beach to Santa Ana. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:18 pm
MYR
- SNA
2 stops41h 51m
Frontier
Deal found 4/24![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:18 pm
MYR
- SNA
2 stops43h 11m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:50 pm
MYR
- SNA
3 stops38h 19m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$186
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:36 pm
MYR
- SNA
1 stop8h 25m
American Airlines
Deal found 4/24![American Airlines logo]()
$203
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:15 pm
MYR
- SNA
1 stop7h 05m
Delta
Deal found 4/25![Delta logo]()
$234
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:26 pm
MYR
- SNA
1 stop6h 57m
American Airlines
Deal found 4/25![American Airlines logo]()
$271
Find flight deals from Myrtle Beach to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $430 (Delta) |
One-way from | $168 (Kiwi.com) |
Popular in | March |
Cheapest in | May |
Average price | $460 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Mon 5/25
4:07 pm-10:29 pm
1 stop9h 22m
Santa Ana J. Wayne/Orange Cnty
Fri 5/29
12:25 pm-11:58 pm
1 stop8h 33m
$436
Quickest round-trip
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Sun 5/24
3:21 pm-8:34 pm
1 stop8h 13m
Santa Ana J. Wayne/Orange Cnty
Tue 6/2
2:00 pm-11:58 pm
1 stop6h 58m
$461
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Thu 6/18
11:41 am-8:24 pm
2 stops11h 43m
Santa Ana J. Wayne/Orange Cnty
Mon 6/22
2:00 pm-11:59 pm
1 stop6h 59m
$472
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Wed 6/17
5:40 pm-8:57 am
2 stops18h 17m
Santa Ana J. Wayne/Orange Cnty
Wed 6/24
6:45 am-7:07 pm
1 stop9h 22m
$512
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Sun 5/24
10:34 am-10:01 pm
2 stops14h 27m
Santa Ana J. Wayne/Orange Cnty
Tue 6/2
6:26 pm-9:59 am
2 stops12h 33m
$545
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Fri 5/15
3:21 pm-9:17 pm
1 stop8h 56m
Santa Ana J. Wayne/Orange Cnty
Sun 5/17
2:00 pm-11:58 pm
1 stop6h 58m
$563
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Thu 5/14
3:14 pm-10:35 pm
1 stop10h 21m
Santa Ana J. Wayne/Orange Cnty
Sat 5/16
6:39 pm-10:42 am
2 stops13h 03m
$592
Cheapest one-way
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Thu 5/28
4:36 pm-10:01 pm
1 stop8h 25m
$203
Quickest one-way
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Fri 9/25
2:15 pm-6:20 pm
1 stop7h 05m
$234
Myrtle BeachSanta Ana
MYR - SNA
MYRSNA
Myrtle Beach Intl
Thu 5/28
6:00 am-10:08 pm
3 stops19h 08m
$237
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santa Ana in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Myrtle Beach with our price prediction graph.
MYR-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated April 29, 2026.
Get a feel of what it's like to fly with American Airlines from Myrtle Beach to Santa Ana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Food
6.4
Comfort
7.2
Entertainment
6.9
Boarding
7.5
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Overall
7.1
Food
6.4
Comfort
7.2
Entertainment
6.9
Boarding
7.5
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
Book flights to Santa Ana if you plan to visit one of these locationsTustin
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Myrtle Beach
Popular flights
Santa Ana flight routes
Alternative routes for Myrtle Beach to Santa Ana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santa Ana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Myrtle Beach to Santa Ana by cabin class
Find flights from Myrtle Beach to Santa Ana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and Santa Ana flights
Browse other Myrtle Beach and Santa Ana flight options. Last updated on April 29, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santa Ana
Explore flights to Santa Ana departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Top airline flying from Myrtle Beach to Santa Ana
Discover the top airline that operate flights from Myrtle Beach to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$306 | Average$415 | FlexibilityNo cancel fee | On-time71% |