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$81+ Cheap flights from Medford to San Diego (MFR - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SAN
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Find cheap flights from Medford to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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3. Compare prices and book

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Cheapflights Tip: The best prices from Medford to San Diego are usually found in June or July, booked 83 days in advance, depart on a Sunday or Thursday and return on a Thursday

Cheap flight deals from Medford to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$157
(Alaska Airlines)

One-way from

$81
(eDestinos)

Popular in

March

Cheapest in

June

Average price

$255

Good round-trip deal

$255 or less

Good one-way deal

$143 or less
Provider with most accurate pricing for Medford-San Diego flight deals.
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Provider most trusted by Cheapflights users for Medford-San Diego flights.
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From Medford to San Diego
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One-way flight from Medford to San Diego
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Highest demand for flights based on searches. 15% potential increase in price ($52 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Medford to San Diego.
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Price to beat on a one-way flight from Medford to San Diego.
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Find flight deals from Medford to San Diego

Cheapest flights from Medford to San Diego
Explore the most affordable flight options available from Medford to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This Alaska Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/181:26 pmMFR - SAN
1 stop7h 30mAlaska Airlines
Wed 11/192:11 pmSAN - MFR
1 stop5h 46mAlaska Airlines
Deal found 10/26$176
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:00 amMFR - SAN
1 stop7h 21mDelta
Sat 12/65:15 pmSAN - MFR
1 stop5h 53mDelta
Deal found 10/26$177
This Alaska Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:55 pmMFR - SAN
Nonstop2h 06mAlaska Airlines
Wed 12/105:58 pmSAN - MFR
1 stop5h 07mAlaska Airlines
Deal found 10/26$181
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/182:05 pmMFR - SAN
2 stops9h 39mUnited Airlines
Wed 11/196:15 amSAN - MFR
1 stop5h 51mUnited Airlines
Deal found 10/26$182
This Alaska Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:20 amMFR - SAN
1 stop4h 39mAlaska Airlines
Wed 12/172:15 pmSAN - MFR
1 stop5h 51mAlaska Airlines
Deal found 10/25$186
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amMFR - SAN
1 stop6h 45mDelta
Thu 12/115:31 pmSAN - MFR
1 stop6h 28mDelta
Deal found 10/26$197
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:00 amMFR - SAN
1 stop8h 04mUnited Airlines
Thu 12/1111:02 amSAN - MFR
2 stops10h 27mUnited Airlines
Deal found 10/25$202
This Alaska Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/81:55 pmMFR - SAN
Nonstop2h 06mAlaska Airlines
Thu 12/1110:55 amSAN - MFR
1 stop4h 34mAlaska Airlines
Deal found 10/25$207
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:20 amMFR - SAN
1 stop6h 40mAmerican Airlines
Fri 11/144:25 pmSAN - MFR
1 stop6h 32mAmerican Airlines
Deal found 10/26$216
This Alaska Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:43 pmMFR - SAN
2 stops14h 56mAlaska Airlines
Fri 12/126:30 pmSAN - MFR
1 stop6h 02mAlaska Airlines
Deal found 10/26$221

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Medford to San Diego that are best for you.

Fly from

Medford

Fly to

San Diego

Route

Depart

Return

Price

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Wed 11/19

5:10 am-9:46 am

1 stop4h 36m

San Diego

Wed 11/19

2:11 pm-7:57 pm

1 stop5h 46m

$176

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Wed 12/10

6:00 am-12:45 pm

1 stop6h 45m

San Diego

Wed 12/10

7:07 pm-11:59 pm

1 stop4h 52m

$177

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 12/6

5:00 am-12:21 pm

1 stop7h 21m

San Diego

Sat 12/6

5:15 pm-11:08 pm

1 stop5h 53m

$177

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 1/1

1:25 pm-3:31 pm

Nonstop2h 06m

San Diego

Wed 1/7

10:22 am-12:45 pm

Nonstop2h 23m

$187

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Tue 11/18

3:45 pm-8:38 pm

1 stop4h 53m

San Diego

Wed 11/19

10:30 am-12:49 pm

Nonstop2h 19m

$187

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 1/1

1:25 pm-3:31 pm

Nonstop2h 06m

San Diego

Tue 1/6

10:32 am-12:56 pm

Nonstop2h 24m

$187

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sun 12/14

5:00 am-12:20 pm

1 stop7h 20m

San Diego

Sun 12/14

7:07 pm-11:59 pm

1 stop4h 52m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 12/11

6:00 am-12:45 pm

1 stop6h 45m

San Diego

Thu 12/11

5:31 pm-11:59 pm

1 stop6h 28m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 1/1

3:47 pm-11:07 pm

1 stop7h 20m

San Diego

Thu 1/8

6:03 pm-10:49 pm

1 stop4h 46m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 12/11

11:40 am-6:13 pm

1 stop6h 33m

San Diego

Fri 12/12

3:15 pm-11:02 pm

1 stop7h 47m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 19 results
1
2

Compare providers for flights from Medford to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to San Diego in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-San Diego flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Medford-San Diego flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Medford-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-San Diego flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to San Diego

How far ahead should I book a flight from Medford to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Medford to San Diego. Price data was last updated on October 24, 2025.

To ensure you get the cheapest price possible for a flight from Medford to San Diego, you should look to book at least 83 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Medford to San Diego?

Currently, July is the cheapest month in which you can book a flight from Medford to San Diego (average of $61). Flying from Medford to San Diego in December is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SAN?

Find hourly flight availability from Medford to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

One of the essential ways to save on airfare from Medford to San Diego is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 43% on airfare.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 27, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and Hawaiian Airlines from Medford to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,194 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,194 reviews
Alaska Airlines
8.0
Very good
11,194 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
7.9
Good
7,996 reviews
Alaska Airlines
8.0
Very good
11,194 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Hawaiian Airlines
7.8
Good
2,792 reviews
Alaska Airlines
8.0
Very good
11,194 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,995 reviews
Alaska Airlines
8.0
Very good
11,194 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Allegiant Air
7.2
Good
695 reviews
Alaska Airlines
8.0
Very good
11,194 reviews

Comfort

7.8

Overall

8.0

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Medford to San Diego?

    Booking a flight from Medford (MFR) to San Diego (SAN) is your only option if you wish to fly from Medford to San Diego. On a typical day, there is 1 flight from Medford to San Diego, all of which are around 2h 05m for a nonstop flight. You can also purchase a plane ticket from 5 airlines when you book a flight from Medford to San Diego.

  • How popular is this Medford to San Diego flight route?

    This flight path from Medford to San Diego was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Medford to San Diego?

    Alaska Airlines and Delta can get you from Medford to San Diego in just under 4h 36m. Your travel time can differ by up to 2h 09m. The distance between Medford and San Diego is about 734 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Medford to San Diego round-trip?

    Our cheapest airline available from Medford to San Diego is Allegiant Air. Our recent data shows that you can find tickets from as low as $54 on this airline. Additional options worth looking into are Hawaiian Airlines and Delta, starting at $131 and $153 round-trip. Users have found that Allegiant Air is 81% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Medford to San Diego?

    Consider Alaska Airlines (83%), Horizon Air (83%) or Hawaiian Airlines (83%) when booking your flight. These represent the most reliable airlines when flying from Medford to San Diego.

  • What are the cheapest flights from Medford to San Diego?

    Looking at all options, your cheapest flight can be booked for $108. While the most popular route (Medford - San Diego) can be booked for $176 on average, our data indicates $261 when flying from Medford to San Diego.

  • Can I find deals for flights from Medford to San Diego that include hotel bookings?

    Yes. In addition to deals on Medford to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to San Diego.

  • Can I find deals for business class flights from Medford to San Diego?

    Yes. Cheapflights offers flight deals from Medford to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to San Diego?

    Currently, July is the cheapest month in which you can book a flight from Medford to San Diego (average of $61). Flying from Medford to San Diego in December is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Imperial Beach
National City

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Top 5 airlines flying from Medford to San Diego

Discover the top 5 airlines that operate flights from Medford to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$54Average$105FlexibilityNo cancel feeOn-time88%
Hawaiian AirlinesCheapest$131Average$257FlexibilityNo cancel feeOn-time85%
DeltaCheapest$153Average$316FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$177Average$297FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$216Average$387FlexibilityNo cancel feeOn-time69%

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