San Diego

$95+ Cheap flights from Medford to San Diego (MFR - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SAN
Oct 11 — Oct 181
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Cheapflights Tip: The best prices from Medford to San Diego are usually found in June or July, booked 40 days in advance, depart on a Sunday or Thursday and return on a Monday

Cheap flight deals from Medford to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$177
(Hawaiian Airlines)

One-way from

$95
(Kiwi.com)

Popular in

March

Cheapest in

June

Average price

$325

Good round-trip deal

$197 or less

Good one-way deal

$138 or less
From Medford to San Diego
One-way flight from Medford to San Diego
Highest demand for flights based on searches. 8% potential increase in price ($29 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Average for round-trip flights in September 2025
Price to beat on a round-trip flight from Medford to San Diego.
Price to beat on a one-way flight from Medford to San Diego.

Find flight deals from Medford to San Diego

Cheapest flights from Medford to San Diego
Explore the most affordable flight options available from Medford to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Hawaiian Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:30 pmMFR - SAN
Nonstop2h 05mHawaiian Airlines
Fri 11/710:30 amSAN - MFR
Nonstop2h 19mHawaiian Airlines
Deal found 9/10$177
This Hawaiian Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:08 pmMFR - SAN
Nonstop2h 06mHawaiian Airlines
Mon 11/310:30 amSAN - MFR
Nonstop2h 19mHawaiian Airlines
Deal found 9/11$197
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/269:42 pmMFR - SAN
1 stop25h 22mMultiple Airlines
Sun 11/28:30 amSAN - MFR
1 stop6h 50mMultiple Airlines
Deal found 9/11$198
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:52 pmMFR - SAN
1 stop5h 34mMultiple Airlines
Sun 9/286:15 amSAN - MFR
1 stop27h 53mMultiple Airlines
Deal found 9/8$209
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/272:13 pmMFR - SAN
1 stop6h 36mUnited Airlines
Sun 9/284:07 pmSAN - MFR
1 stop4h 22mUnited Airlines
Deal found 9/10$217
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/272:13 pmMFR - SAN
2 stops5h 33mUnited Airlines
Mon 9/294:07 pmSAN - MFR
1 stop4h 22mUnited Airlines
Deal found 9/10$222
This Alaska Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/222:19 pmMFR - SAN
Nonstop2h 08mAlaska Airlines
Tue 11/2511:19 amSAN - MFR
Nonstop2h 23mAlaska Airlines
Deal found 9/10$227
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:40 pmMFR - SAN
1 stop4h 44mAmerican Airlines
Sun 10/54:40 pmSAN - MFR
1 stop6h 20mAmerican Airlines
Deal found 9/9$232
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/99:42 pmMFR - SAN
1 stop14h 35mMultiple Airlines
Thu 10/166:25 amSAN - MFR
1 stop8h 51mMultiple Airlines
Deal found 9/10$233
This Alaska Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/312:30 pmMFR - SAN
Nonstop2h 05mAlaska Airlines
Wed 11/510:30 amSAN - MFR
Nonstop2h 19mAlaska Airlines
Deal found 9/11$237

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Medford to San Diego that are best for you.

Fly from

Medford

Fly to

San Diego

Route

Depart

Return

Price

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 11/1

12:30 pm-2:35 pm

Nonstop2h 05m

San Diego

Fri 11/7

10:30 am-12:49 pm

Nonstop2h 19m

$177

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Mon 11/3

6:00 am-12:38 pm

1 stop6h 38m

San Diego

Wed 11/5

3:15 pm-10:50 pm

1 stop7h 35m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Wed 10/22

6:00 am-12:38 pm

1 stop6h 38m

San Diego

Mon 11/3

3:15 pm-10:50 pm

1 stop7h 35m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Wed 10/22

4:08 pm-6:14 pm

Nonstop2h 06m

San Diego

Mon 11/3

10:30 am-12:49 pm

Nonstop2h 19m

$197

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Mon 11/3

3:45 pm-8:29 pm

1 stop4h 44m

San Diego

Wed 11/5

10:30 am-12:49 pm

Nonstop2h 19m

$207

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 9/25

2:40 pm-7:48 pm

1 stop5h 08m

San Diego

Tue 9/30

6:20 am-1:28 pm

1 stop7h 08m

$217

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 9/27

2:13 pm-8:49 pm

1 stop6h 36m

San Diego

Sun 9/28

4:07 pm-8:29 pm

1 stop4h 22m

$217

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Sat 9/27

6:15 am-12:57 pm

1 stop6h 42m

San Diego

Mon 9/29

7:29 am-3:34 pm

1 stop8h 05m

$217

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 10/9

9:42 pm-12:17 pm

1 stop14h 35m

San Diego

Thu 10/16

6:25 am-3:16 pm

1 stop8h 51m

$233

MedfordSan Diego

MFR - SAN

MFRSAN

Medford

Thu 10/9

4:08 pm-6:14 pm

Nonstop2h 06m

San Diego

Thu 10/16

11:43 am-2:01 pm

Nonstop2h 18m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 21 results
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Best time to book a flight from Medford to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to San Diego

How far ahead should I book a flight from Medford to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Medford to San Diego. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Medford to San Diego, you should look to book at least 40 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Medford to San Diego?

Currently, August is the cheapest month in which you can book a flight from Medford to San Diego (average of $286). Flying from Medford to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SAN?

Find hourly flight availability from Medford to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Medford to San Diego is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 38% on airfare.

How much does it cost to fly round-trip from Medford to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and Hawaiian Airlines from Medford to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
8.0
Very good

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Boarding

8.1

Entertainment

7.0

Comfort

7.8

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Medford to San Diego?

    Booking a flight from Medford (MFR) to San Diego (SAN) is your only option if you wish to fly from Medford to San Diego. On a typical day, there are 2 flights from Medford to San Diego, all of which are around 2h 05m for a nonstop flight. You can also purchase a plane ticket from 5 airlines when you book a flight from Medford to San Diego.

  • How popular is this Medford to San Diego flight route?

  • How long is the flight from Medford to San Diego?

    Hawaiian Airlines, Delta, and Alaska Airlines can get you from Medford to San Diego in just under 2h 05m. Your travel time can differ by up to 4h 33m. The distance between Medford and San Diego is about 734 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Medford to San Diego round-trip?

    Our cheapest airline available from Medford to San Diego is Allegiant Air. Our recent data shows that you can find tickets from as low as $54 on this airline. Additional options worth looking into are Hawaiian Airlines and Alaska Airlines, starting at $131 and $177 round-trip. Users have found that Allegiant Air is 83% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Medford to San Diego?

    Consider Alaska Airlines (80%), Horizon Air (80%) or Hawaiian Airlines (80%) when booking your flight. These represent the most reliable airlines when flying from Medford to San Diego.

  • What are the cheapest flights from Medford to San Diego?

    Looking at all options, your cheapest flight can be booked for $81. While the most popular route (Medford - San Diego) can be booked for $177 on average, our data indicates $303 when flying from Medford to San Diego.

  • Where are the most common layover locations when flying from Medford to San Diego?

  • What are some popular things to do or see while on a layover in Seattle?

    Seattle travelers tend to visit Pike Place Market, Space Needle, and Seattle Waterfront more than anywhere else. Pike Place Market, Space Needle, and Seattle Waterfront can be accessed by traveling approximately 11.2 mi, 12.0 mi, and 10.9 mi, respectively from Seattle/Tacoma Intl. Those looking to explore during their layover in Seattle can rent a car from Seattle/Tacoma Intl for about $67 per day.

  • Where are the least popular layover locations for Medford to San Diego flights?

  • Can I find deals for flights from Medford to San Diego that include hotel bookings?

    Yes. In addition to deals on Medford to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to San Diego.

  • Can I find deals for business class flights from Medford to San Diego?

    Yes. Cheapflights offers flight deals from Medford to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Medford to San Diego (average of $286). Flying from Medford to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine

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Top 5 airlines flying from Medford to San Diego

Discover the top 5 airlines that operate flights from Medford to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$54Average$105FlexibilityNo cancel feeOn-time88%
Hawaiian AirlinesCheapest$131Average$257FlexibilityNo cancel feeOn-time85%
Alaska AirlinesCheapest$177Average$339FlexibilityNo cancel feeOn-time75%
DeltaCheapest$196Average$317FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$246Average$387FlexibilityNo cancel feeOn-time69%

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