$192+ Cheap flights from Greenville to San Diego (GSP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
Mai 10 — Mai 171
Round-trip
1 adult, Economy
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Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/65:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Di 5/1212:05 pm
SAN
- GSP
1 stop6h 35m
Southwest
Deal found 4/7![Southwest logo]()
$383
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/98:02 am
GSP
- SAN
1 stop8h 12m
American Airlines
Mi 5/271:21 pm
SAN
- GSP
1 stop7h 31m
American Airlines
Deal found 4/8![American Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/235:25 pm
GSP
- SAN
1 stop8h 50m
Southwest
Di 5/266:45 am
SAN
- GSP
2 stops11h 55m
Southwest
Deal found 4/7![Southwest logo]()
$402
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/246:41 pm
GSP
- SAN
1 stop7h 58m
American Airlines
Di 6/3010:28 pm
SAN
- GSP
1 stop8h 40m
American Airlines
Deal found 4/6![American Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/216:25 am
GSP
- SAN
2 stops8h 20m
Southwest
Sa 5/239:40 pm
SAN
- GSP
1 stop9h 30m
Southwest
Deal found 4/9![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/66:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Mi 5/1312:05 pm
SAN
- GSP
1 stop6h 35m
Southwest
Deal found 4/9![Southwest logo]()
$405
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/312:50 pm
GSP
- SAN
2 stops8h 25m
Southwest
Mi 6/1010:10 am
SAN
- GSP
1 stop8h 50m
Southwest
Deal found 4/8![Southwest logo]()
$416
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/312:50 pm
GSP
- SAN
2 stops8h 25m
Southwest
Mi 6/1010:10 am
SAN
- GSP
1 stop8h 50m
Southwest
Deal found 4/8![Southwest logo]()
$416
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 8/85:16 pm
GSP
- SAN
1 stop8h 41m
Delta
Mi 8/1210:30 pm
SAN
- GSP
1 stop8h 58m
Delta
Deal found 4/5![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/96:00 am
GSP
- SAN
1 stop8h 21m
United Airlines
Di 6/2310:40 pm
SAN
- GSP
1 stop8h 31m
United Airlines
Deal found 4/10![United Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/2310:45 am
GSP
- SAN
2 stops8h 45m
Southwest
Di 5/266:45 am
SAN
- GSP
2 stops11h 55m
Southwest
Deal found 4/7![Southwest logo]()
$427
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/2811:43 am
GSP
- SAN
1 stop9h 18m
Delta
So 5/3110:15 pm
SAN
- GSP
1 stop9h 40m
Delta
Deal found 4/5![Delta logo]()
$433
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/912:50 pm
GSP
- SAN
2 stops8h 50m
Southwest
Di 6/2310:40 pm
SAN
- GSP
1 stop10h 35m
Southwest
Deal found 4/10![Southwest logo]()
$444
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/287:28 am
GSP
- SAN
1 stop9h 52m
Delta
Di 5/127:10 pm
SAN
- GSP
2 stops12h 25m
Delta
Deal found 4/6![Delta logo]()
$475
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 6/412:55 pm
GSP
- SAN
2 stops9h 10m
Southwest
So 6/710:40 pm
SAN
- GSP
1 stop10h 35m
Southwest
Deal found 4/9![Southwest logo]()
$454
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/226:25 am
GSP
- SAN
2 stops9h 15m
Southwest
So 5/247:00 am
SAN
- GSP
1 stop7h 15m
Southwest
Deal found 4/9![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 9/248:40 am
GSP
- SAN
2 stops12h 30m
Southwest
Fr 10/29:50 pm
SAN
- GSP
1 stop9h 15m
Southwest
Deal found 4/8![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 9/1511:00 am
GSP
- SAN
2 stops8h 55m
Southwest
So 9/2010:40 pm
SAN
- GSP
1 stop14h 25m
Southwest
Deal found 4/6![Southwest logo]()
$478
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated April 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 4/286:26 pm
GSP
- SAN
1 stop7h 40m
Delta
Di 5/126:15 am
SAN
- GSP
1 stop7h 02m
Delta
Deal found 4/8![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/65:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Di 5/1212:05 pm
SAN
- GSP
1 stop6h 35m
Southwest
Deal found 4/7![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/66:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Mi 5/1312:05 pm
SAN
- GSP
1 stop6h 35m
Southwest
Deal found 4/9![Southwest logo]()
$405
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 5/82:37 pm
GSP
- SAN
1 stop7h 23m
American Airlines
Di 5/1211:01 am
SAN
- GSP
1 stop8h 39m
American Airlines
Deal found 4/6![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/98:02 am
GSP
- SAN
1 stop8h 12m
American Airlines
Mi 5/271:21 pm
SAN
- GSP
1 stop7h 31m
American Airlines
Deal found 4/8![American Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/216:25 am
GSP
- SAN
2 stops8h 20m
Southwest
Sa 5/239:40 pm
SAN
- GSP
1 stop9h 30m
Southwest
Deal found 4/9![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/235:25 pm
GSP
- SAN
1 stop8h 50m
Southwest
Di 5/266:45 am
SAN
- GSP
2 stops11h 55m
Southwest
Deal found 4/7![Southwest logo]()
$402
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 6/235:41 pm
GSP
- SAN
1 stop7h 53m
United Airlines
Deal found 4/8![United Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/33:31 pm
GSP
- SAN
3 stops35h 22m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$195
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/216:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Deal found 4/9![Southwest logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 5/243:27 pm
GSP
- SAN
3 stops44h 15m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 6/214:03 pm
GSP
- SAN
3 stops58h 50m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 8/36:19 pm
GSP
- SAN
1 stop20h 20m
Breeze Airways
Deal found 4/6![Breeze Airways logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/213:27 pm
GSP
- SAN
3 stops56h 45m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 9/285:15 pm
GSP
- SAN
1 stop7h 38m
United Airlines
Deal found 4/9![United Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 5/248:35 am
GSP
- SAN
1 stop9h 35m
Southwest
Deal found 4/9![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 4/175:43 pm
GSP
- SAN
3 stops41h 51m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$272
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $383 (Southwest) |
One-way from | $192 (United Airlines) |
Popular in | April |
Cheapest in | January |
Average price | $541 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Mi 6/3
12:50 pm-6:15 pm
2 stops8h 25m
San Diego
Mi 6/10
10:10 am-10:00 pm
1 stop8h 50m
$416
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sa 8/8
5:16 pm-10:57 pm
1 stop8h 41m
San Diego
Mi 8/12
10:30 pm-10:28 am
1 stop8h 58m
$425
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sa 5/23
10:45 am-4:30 pm
2 stops8h 45m
San Diego
Di 5/26
6:45 am-9:40 pm
2 stops11h 55m
$427
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Di 6/9
6:00 am-11:21 am
1 stop8h 21m
San Diego
Di 6/23
10:40 pm-10:11 am
1 stop8h 31m
$433
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Do 5/28
11:43 am-6:01 pm
1 stop9h 18m
San Diego
So 5/31
10:15 pm-10:55 am
1 stop9h 40m
$433
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Di 6/9
12:50 pm-6:40 pm
2 stops8h 50m
San Diego
Di 6/23
10:40 pm-12:15 pm
1 stop10h 35m
$444
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Do 6/4
12:55 pm-7:05 pm
2 stops9h 10m
San Diego
So 6/7
10:40 pm-12:15 pm
1 stop10h 35m
$454
Quickest round-trip
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Fr 5/22
6:25 am-12:40 pm
2 stops9h 15m
San Diego
So 5/24
7:00 am-5:15 pm
1 stop7h 15m
$472
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Do 9/24
8:40 am-6:10 pm
2 stops12h 30m
San Diego
Fr 10/2
9:50 pm-10:05 am
1 stop9h 15m
$472
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Di 4/28
7:28 am-2:20 pm
1 stop9h 52m
San Diego
Di 5/12
7:10 pm-10:35 am
2 stops12h 25m
$475
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
GSP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Diego
How far ahead should I book a flight from Greenville to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Diego. Price data was last updated on April 9, 2026.
The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Diego?
Currently, March is the cheapest month in which you can book a flight from Greenville to San Diego (average of $96). Flying from Greenville to San Diego in February is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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Alternative routes for Greenville to San Diego
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Greenville and San Diego flights
Browse other Greenville and San Diego flight options. Last updated on April 10, 2026.
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Top 4 airlines flying from Greenville to San Diego
Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$419 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$305 | Average$516 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$477 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$312 | Average$470 | FlexibilityNo cancel fee | On-time71% |