$148+ Cheap flights from Greenville to San Diego (GSP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:06 pm
GSP
- SAN
1 stop8h 42m
American Airlines
Tue 6/21:21 pm
SAN
- GSP
1 stop7h 31m
American Airlines
Deal found 3/17![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:45 am
GSP
- SAN
1 stop7h 00m
Southwest
Tue 5/129:15 am
SAN
- GSP
2 stops9h 25m
Southwest
Deal found 3/18![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:02 am
GSP
- SAN
1 stop8h 12m
American Airlines
Wed 5/2710:28 pm
SAN
- GSP
1 stop6h 50m
American Airlines
Deal found 3/20![American Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 am
GSP
- SAN
1 stop7h 55m
United Airlines
Sat 4/258:45 am
SAN
- GSP
2 stops9h 02m
United Airlines
Deal found 3/17![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:41 pm
GSP
- SAN
1 stop8h 18m
United Airlines
Thu 4/2310:30 pm
SAN
- GSP
1 stop8h 16m
United Airlines
Deal found 3/17![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Sat 5/27:35 am
SAN
- GSP
2 stops10h 05m
Southwest
Deal found 3/18![Southwest logo]()
$401
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Wed 4/2210:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 3/19![Southwest logo]()
$405
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:12 pm
GSP
- SAN
1 stop7h 48m
American Airlines
Thu 4/231:36 pm
SAN
- GSP
1 stop7h 21m
American Airlines
Deal found 3/19![American Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:55 pm
GSP
- SAN
2 stops9h 10m
Southwest
Mon 6/86:30 am
SAN
- GSP
2 stops8h 45m
Southwest
Deal found 3/19![Southwest logo]()
$409
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Thu 4/96:20 am
SAN
- GSP
2 stops8h 30m
Southwest
Deal found 3/18![Southwest logo]()
$416
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 am
GSP
- SAN
1 stop7h 55m
United Airlines
Sat 4/258:45 am
SAN
- GSP
2 stops9h 02m
United Airlines
Deal found 3/17![United Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 pm
GSP
- SAN
1 stop7h 35m
Southwest
Mon 6/86:30 am
SAN
- GSP
2 stops8h 45m
Southwest
Deal found 3/19![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:42 am
GSP
- SAN
1 stop7h 07m
Delta
Tue 5/127:10 pm
SAN
- GSP
2 stops10h 54m
Delta
Deal found 3/19![Delta logo]()
$462
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:50 pm
GSP
- SAN
2 stops8h 25m
Southwest
Sat 4/258:10 am
SAN
- GSP
2 stops9h 30m
Southwest
Deal found 3/17![Southwest logo]()
$418
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/73:42 pm
GSP
- SAN
1 stop8h 37m
Delta
Sat 9/122:00 pm
SAN
- GSP
1 stop6h 38m
Delta
Deal found 3/19![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:41 pm
GSP
- SAN
1 stop7h 53m
United Airlines
Fri 6/1910:30 pm
SAN
- GSP
1 stop9h 07m
United Airlines
Deal found 3/19![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Thu 4/96:20 am
SAN
- GSP
2 stops8h 30m
Southwest
Deal found 3/18![Southwest logo]()
$450
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:05 pm
GSP
- SAN
1 stop8h 53m
Delta
Sun 6/2810:30 pm
SAN
- GSP
1 stop8h 58m
Delta
Deal found 3/17![Delta logo]()
$467
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:15 am
GSP
- SAN
1 stop9h 53m
Delta
Mon 7/610:40 pm
SAN
- GSP
1 stop7h 47m
Delta
Deal found 3/21![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:50 pm
GSP
- SAN
1 stop7h 35m
Southwest
Fri 7/2411:15 am
SAN
- GSP
1 stop7h 20m
Southwest
Deal found 3/17![Southwest logo]()
$467
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:45 am
GSP
- SAN
1 stop7h 50m
Delta
Sun 6/2110:30 pm
SAN
- GSP
1 stop8h 58m
Delta
Deal found 3/18![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:50 pm
GSP
- SAN
1 stop7h 35m
Southwest
Sat 7/49:40 pm
SAN
- GSP
1 stop12h 25m
Southwest
Deal found 3/17![Southwest logo]()
$472
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated March 22, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Thu 4/96:20 am
SAN
- GSP
2 stops8h 30m
Southwest
Deal found 3/18![Southwest logo]()
$416
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Wed 4/2210:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 3/19![Southwest logo]()
$405
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:41 pm
GSP
- SAN
1 stop8h 18m
United Airlines
Thu 4/2310:30 pm
SAN
- GSP
1 stop8h 16m
United Airlines
Deal found 3/17![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:12 pm
GSP
- SAN
1 stop7h 48m
American Airlines
Thu 4/231:36 pm
SAN
- GSP
1 stop7h 21m
American Airlines
Deal found 3/19![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 am
GSP
- SAN
1 stop7h 55m
United Airlines
Sat 4/2510:30 pm
SAN
- GSP
1 stop8h 16m
United Airlines
Deal found 3/17![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:45 am
GSP
- SAN
1 stop7h 00m
Southwest
Tue 5/1212:05 pm
SAN
- GSP
1 stop6h 35m
Southwest
Deal found 3/18![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Sat 5/27:35 am
SAN
- GSP
2 stops10h 05m
Southwest
Deal found 3/18![Southwest logo]()
$401
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:57 am
GSP
- SAN
1 stop9h 16m
American Airlines
Tue 5/1212:17 pm
SAN
- GSP
1 stop7h 23m
American Airlines
Deal found 3/22![American Airlines logo]()
$417
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:43 pm
GSP
- SAN
2 stops51h 16m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:43 pm
GSP
- SAN
3 stops32h 23m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:43 pm
GSP
- SAN
3 stops32h 23m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:18 pm
GSP
- SAN
2 stops39h 16m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$182
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:41 pm
GSP
- SAN
1 stop8h 18m
United Airlines
Deal found 3/20![United Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:45 pm
GSP
- SAN
3 stops29h 29m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$198
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:41 pm
GSP
- SAN
1 stop7h 45m
United Airlines
Deal found 3/17![United Airlines logo]()
$200
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $383 (American Airlines) |
One-way from | $148 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $516 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Wed 4/22
6:30 am-11:25 am
1 stop7h 55m
San Diego
Sat 4/25
8:45 am-8:47 pm
2 stops9h 02m
$396
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 6/4
6:50 pm-11:25 pm
1 stop7h 35m
San Diego
Mon 6/8
6:30 am-6:15 pm
2 stops8h 45m
$404
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Wed 4/22
12:50 pm-6:15 pm
2 stops8h 25m
San Diego
Sat 4/25
8:10 am-8:40 pm
2 stops9h 30m
$418
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 4/7
6:45 am-12:55 pm
2 stops9h 10m
San Diego
Thu 4/9
6:20 am-5:50 pm
2 stops8h 30m
$450
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 4/28
5:42 am-9:49 am
1 stop7h 07m
San Diego
Tue 5/12
7:10 pm-9:04 am
2 stops10h 54m
$462
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Mon 9/7
3:42 pm-9:19 pm
1 stop8h 37m
San Diego
Sat 9/12
2:00 pm-11:38 pm
1 stop6h 38m
$467
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Fri 6/12
5:41 pm-10:34 pm
1 stop7h 53m
San Diego
Fri 6/19
10:30 pm-10:37 am
1 stop9h 07m
$467
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Mon 6/15
5:05 pm-10:58 pm
1 stop8h 53m
San Diego
Sun 6/28
10:30 pm-10:28 am
1 stop8h 58m
$467
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 7/2
7:15 am-2:08 pm
1 stop9h 53m
San Diego
Mon 7/6
10:40 pm-9:27 am
1 stop7h 47m
$467
Quickest round-trip
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Mon 7/20
6:50 pm-11:25 pm
1 stop7h 35m
San Diego
Fri 7/24
11:15 am-9:35 pm
1 stop7h 20m
$467
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
GSP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Diego
How far ahead should I book a flight from Greenville to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Diego. Price data was last updated on March 13, 2026.
The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Diego?
Currently, March is the cheapest month in which you can book a flight from Greenville to San Diego (average of $96). Flying from Greenville to San Diego in February is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 22, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 4 airlines flying from Greenville to San Diego
Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$465 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$477 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$356 | Average$516 | FlexibilityNo cancel fee | On-time63% |