$150+ Cheap flights from Greenville to San Diego (GSP - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
Oct 6 — Oct 131
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Diego
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Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:17 pm -
1 stop7h 33m
Mon 11/910:20 pm -
1 stop9h 02m
Deal found 9/2![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:20 am -
2 stops8h 20m
Tue 1/56:35 am -
1 stop10h 15m
Deal found 9/3![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 pm -
1 stop7h 29m
Mon 9/2810:20 pm -
1 stop9h 04m
Deal found 9/1![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:40 pm -
1 stop6h 55m
Thu 10/296:45 am -
1 stop11h 50m
Deal found 9/2![Southwest logo]()
$317
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:25 pm -
1 stop7h 14m
Tue 1/510:40 pm -
1 stop7h 45m
Deal found 9/3![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:55 pm -
1 stop7h 35m
Tue 9/299:35 am -
2 stops8h 20m
Deal found 9/2![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:05 am -
2 stops9h 25m
Mon 11/98:00 am -
2 stops9h 10m
Deal found 9/1![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:24 pm -
1 stop7h 24m
Sat 9/269:50 am -
1 stop9h 21m
Deal found 9/1![American Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:20 pm -
1 stop6h 50m
Fri 10/910:40 pm -
1 stop10h 30m
Deal found 9/3![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:15 am -
1 stop9h 54m
Tue 9/296:20 am -
1 stop8h 26m
Deal found 9/2![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:40 am -
2 stops9h 05m
Tue 1/57:10 am -
2 stops8h 00m
Deal found 9/3![Southwest logo]()
$360
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:46 pm -
1 stop7h 55m
Tue 9/296:40 am -
1 stop7h 25m
Deal found 9/2![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:55 pm -
1 stop7h 35m
Mon 9/2810:40 pm -
1 stop8h 35m
Deal found 9/1![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 pm -
1 stop7h 29m
Fri 10/910:25 pm -
1 stop8h 36m
Deal found 9/5![Delta logo]()
$440
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:40 am -
2 stops8h 40m
Tue 1/56:35 am -
1 stop10h 15m
Deal found 9/3![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:20 am -
2 stops14h 06m
Tue 9/296:40 am -
2 stops13h 33m
Deal found 9/2![United Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:40 pm -
1 stop6h 55m
Thu 10/2211:10 am -
2 stops8h 40m
Deal found 9/1![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:20 pm -
1 stop6h 50m
Fri 10/911:20 am -
2 stops8h 30m
Deal found 9/3![Southwest logo]()
$415
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
1 stop8h 07m
Sat 10/316:26 pm -
2 stops13h 04m
Deal found 9/5![United Airlines logo]()
$516
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:40 pm -
1 stop6h 55m
Tue 10/139:35 am -
2 stops8h 30m
Deal found 9/4![Southwest logo]()
$495
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:40 pm -
1 stop9h 10m
Sat 10/38:00 am -
2 stops9h 35m
Deal found 9/4![Southwest logo]()
$504
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated September 6, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated September 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:24 pm -
1 stop7h 24m
Sat 9/269:50 am -
1 stop9h 21m
Deal found 9/1![American Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:15 am -
1 stop9h 54m
Tue 9/296:20 am -
1 stop8h 26m
Deal found 9/2![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 am -
1 stop7h 00m
Tue 9/2912:52 pm -
1 stop7h 03m
Deal found 9/2![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:40 pm -
1 stop9h 10m
Tue 9/298:35 am -
2 stops9h 20m
Deal found 9/2![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 pm -
1 stop7h 29m
Mon 9/2810:20 pm -
1 stop9h 04m
Deal found 9/1![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:55 pm -
1 stop7h 35m
Tue 9/299:35 am -
2 stops8h 20m
Deal found 9/2![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:05 pm -
2 stops11h 55m
Mon 9/2810:40 pm -
1 stop8h 35m
Deal found 9/1![Southwest logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:24 pm -
1 stop7h 24m
Wed 10/79:25 pm -
1 stop7h 59m
Deal found 9/1![American Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:25 pm -
1 stop7h 29m
Wed 10/712:38 pm -
1 stop7h 13m
Deal found 9/3![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:20 pm -
1 stop6h 50m
Fri 10/910:40 pm -
1 stop10h 30m
Deal found 9/3![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:40 pm -
1 stop6h 55m
Thu 10/2911:40 am -
2 stops8h 10m
Deal found 9/2![Southwest logo]()
$317
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:25 pm -
1 stop7h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![United Airlines logo]()
$150
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:40 pm -
1 stop6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Southwest logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:29 pm -
3 stops58h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:10 pm -
3 stops31h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:34 pm -
2 stops26h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:02 pm -
3 stops51h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$197
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:29 pm -
1 stop9h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:29 pm -
3 stops48h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$202
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $150 (Delta) |
Popular in | June |
Cheapest in | August |
Average price | $570 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Tue 9/29
8:05 am-11:25 am
1 stop6h 20m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 10/3
4:25 pm-8:39 pm
1 stop7h 14m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Wed 12/16
10:27 am-4:28 pm
1 stop9h 01m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 10/3
7:20 am-11:25 am
1 stop7h 05m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Thu 10/29
1:05 pm-5:10 pm
1 stop7h 05m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$201
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Wed 10/28
4:29 pm-10:30 pm
1 stop9h 01m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$201
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Thu 11/5
4:29 pm-10:30 pm
1 stop9h 01m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$201
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 9/26
2:16 pm-6:40 pm
1 stop7h 24m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$201
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Wed 12/16
3:26 pm-8:45 pm
1 stop8h 19m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$206
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Fri 9/25
5:46 pm-10:41 pm
1 stop7h 55m
San Diego
Tue 9/29
6:40 am-5:05 pm
1 stop7h 25m
$312
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
GSP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Diego
How far ahead should I book a flight from Greenville to San Diego?
The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 54 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Diego?
Currently, August is the cheapest month in which you can book a flight from Greenville to San Diego (average of $362). Flying from Greenville to San Diego in June is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Diego?
Airfare is below average for this route at the moment.
Greenville to San Diego flights typically cost between $383 and $622 in November.The cheapest round-trip price found within the last 5 days was $299 on American Airlines (Nov 4-Nov 9).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 6, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
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Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Greenville and San Diego flights
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Top 4 airlines flying from Greenville to San Diego
Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$304 | Average$478 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$305 | Average$511 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$466 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$321 | Average$479 | FlexibilityNo cancel fee | On-time71% |