San Diego

$153+ Cheap flights from Greenville to San Diego (GSP - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
Feb 14 — Feb 211
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1. Tell us where you want to go

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Cheap flight deals from Greenville to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$364
(American Airlines)

One-way from

$153
(Kiwi.com)

Popular in

February

Cheapest in

July

Average price

$362
Provider with most accurate pricing for Greenville-San Diego flight deals.
Provider most trusted by Cheapflights users for Greenville-San Diego flights.
From Greenville to San Diego
One-way flight from Greenville to San Diego
Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Find flight deals from Greenville to San Diego

Cheapest flights from Greenville to San Diego
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1010:23 am
GSP
-
SAN
1 stop9h 31m
American Airlines
Tue 3/36:20 am
SAN
-
GSP
1 stop10h 26m
American Airlines
Deal found 1/14$364
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1010:05 am
GSP
-
SAN
2 stops9h 50m
Southwest
Tue 3/37:55 pm
SAN
-
GSP
2 stops11h 45m
Southwest
Deal found 1/14$378
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/912:30 pm
GSP
-
SAN
1 stop9h 50m
Southwest
Thu 2/126:30 am
SAN
-
GSP
1 stop6h 05m
Southwest
Deal found 1/14$393
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1410:35 am
GSP
-
SAN
2 stops9h 20m
Southwest
Sat 2/216:20 am
SAN
-
GSP
2 stops11h 30m
Southwest
Deal found 1/14$404
This Southwest deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:30 pm
GSP
-
SAN
1 stop9h 50m
Southwest
Sun 2/226:30 am
SAN
-
GSP
1 stop6h 05m
Southwest
Deal found 1/13$407
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:19 pm
GSP
-
SAN
1 stop7h 50m
American Airlines
Thu 2/2610:45 pm
SAN
-
GSP
1 stop9h 11m
American Airlines
Deal found 1/13$413
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 am
GSP
-
SAN
1 stop8h 54m
American Airlines
Tue 4/146:15 am
SAN
-
GSP
1 stop10h 34m
American Airlines
Deal found 1/14$414
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:15 am
GSP
-
SAN
1 stop9h 53m
Delta
Fri 5/229:40 pm
SAN
-
GSP
1 stop8h 48m
Delta
Deal found 1/13$417
This Southwest deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:20 am
GSP
-
SAN
2 stops9h 25m
Southwest
Sun 3/156:35 am
SAN
-
GSP
1 stop12h 10m
Southwest
Deal found 1/13$418

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

Fly from

Greenville

Fly to

San Diego

Route

Depart

Return

Price

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 2/10

6:00 am-11:40 am

2 stops8h 40m

San Diego

Tue 3/3

6:20 am-7:46 pm

1 stop10h 26m

$369

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 2/10

10:05 am-4:55 pm

2 stops9h 50m

San Diego

Tue 3/3

7:55 pm-10:40 am

2 stops11h 45m

$378

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 2/19

5:20 am-11:17 am

1 stop8h 57m

San Diego

Mon 2/23

1:04 pm-12:22 am

1 stop8h 18m

$393

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Thu 2/19

10:45 am-6:00 pm

2 stops10h 15m

San Diego

Mon 2/23

6:25 am-6:00 pm

2 stops8h 35m

$404

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Sat 2/14

10:35 am-4:55 pm

2 stops9h 20m

San Diego

Sat 2/21

6:20 am-8:50 pm

2 stops11h 30m

$404

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Fri 4/10

4:10 pm-10:30 pm

1 stop9h 20m

San Diego

Tue 4/14

10:52 am-8:47 pm

1 stop6h 55m

$407

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 3/10

5:40 am-9:52 am

1 stop7h 12m

San Diego

Sun 3/15

10:30 pm-9:26 am

1 stop7h 56m

$407

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Fri 5/8

6:25 pm-10:55 pm

1 stop7h 30m

San Diego

Tue 5/12

6:50 am-4:20 pm

1 stop6h 30m

$407

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 2/17

12:30 pm-7:20 pm

1 stop9h 50m

San Diego

Sun 2/22

6:30 am-3:35 pm

1 stop6h 05m

$407

GreenvilleSan Diego

GSP - SAN

GSPSAN

Greenville

Tue 5/19

6:45 am-12:55 pm

2 stops9h 10m

San Diego

Fri 5/22

9:40 pm-10:10 am

1 stop9h 30m

$412

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 19 results
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Compare providers for flights from Greenville to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Diego

How far ahead should I book a flight from Greenville to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Diego. Price data was last updated on January 9, 2026.

The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Greenville to San Diego?

Currently, June is the cheapest month in which you can book a flight from Greenville to San Diego (average of $105). Flying from Greenville to San Diego in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated January 15, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Greenville to San Diego?

    There are many flights that can get you from Greenville to San Diego in 8h 40m. Fly via American Airlines or Southwest to get the fastest option. Greenville and San Diego are separated by a distance of 2002 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Greenville to San Diego round-trip?

    Cheapflights users have booked flights from Greenville to San Diego round-trip from $148. Other airlines that can offer you cheap pricing are American Airlines, from $286, and United Airlines, from $312. These flights start at 64% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Greenville to San Diego one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $131. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Greenville to San Diego for a low price.

  • Can I find deals for flights from Greenville to San Diego that include hotel bookings?

    Yes. In addition to deals on Greenville to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Diego.

  • Can I find deals for business class flights from Greenville to San Diego?

    Yes. Cheapflights offers flight deals from Greenville to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Greenville to San Diego (average of $105). Flying from Greenville to San Diego in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Alternative routes for Greenville to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Greenville to San Diego

Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$410FlexibilityNo cancel feeOn-time71%
DeltaCheapest$287Average$414FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$312Average$451FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$350Average$492FlexibilityNo cancel feeOn-time63%

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