$133+ Cheap flights from Greenville to San Diego (GSP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
Mar 4 — Mar 111
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Diego
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Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:50 pm
GSP
- SAN
1 stop7h 40m
Southwest
Wed 4/229:40 pm
SAN
- GSP
1 stop12h 35m
Southwest
Deal found 2/1![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:40 am
GSP
- SAN
1 stop7h 21m
Delta
Tue 3/311:16 am
SAN
- GSP
1 stop6h 03m
Delta
Deal found 1/31![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:10 pm
GSP
- SAN
1 stop7h 10m
Southwest
Sat 5/27:40 am
SAN
- GSP
1 stop10h 55m
Southwest
Deal found 2/1![Southwest logo]()
$385
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:14 pm
GSP
- SAN
1 stop7h 45m
Delta
Tue 4/710:30 pm
SAN
- GSP
1 stop7h 56m
Delta
Deal found 2/1![Delta logo]()
$393
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:25 pm
GSP
- SAN
1 stop8h 50m
Southwest
Sat 5/98:20 am
SAN
- GSP
2 stops9h 20m
Southwest
Deal found 2/1![Southwest logo]()
$398
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:00 pm
GSP
- SAN
1 stop6h 51m
Delta
Thu 3/510:20 pm
SAN
- GSP
1 stop7h 45m
Delta
Deal found 1/31![Delta logo]()
$412
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:40 am
GSP
- SAN
1 stop7h 13m
Delta
Sun 4/510:30 pm
SAN
- GSP
1 stop7h 56m
Delta
Deal found 2/1![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:40 am
GSP
- SAN
1 stop7h 21m
Delta
Tue 3/312:00 pm
SAN
- GSP
1 stop7h 24m
Delta
Deal found 1/31![Delta logo]()
$428
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:30 pm
GSP
- SAN
1 stop9h 50m
Southwest
Tue 2/247:40 pm
SAN
- GSP
2 stops12h 00m
Southwest
Deal found 1/31![Southwest logo]()
$433
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 2, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 2, 2026.
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:40 am
GSP
- SAN
1 stop7h 21m
Delta
Tue 3/311:16 am
SAN
- GSP
1 stop6h 03m
Delta
Deal found 1/31![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:50 pm
GSP
- SAN
2 stops8h 35m
Southwest
Wed 4/2210:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 2/1![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:18 pm
GSP
- SAN
1 stop8h 30m
Delta
Tue 3/312:00 pm
SAN
- GSP
1 stop7h 24m
Delta
Deal found 1/31![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:10 pm
GSP
- SAN
1 stop7h 10m
Southwest
Sat 5/27:40 am
SAN
- GSP
1 stop10h 55m
Southwest
Deal found 2/1![Southwest logo]()
$385
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:30 am
GSP
- SAN
1 stop9h 50m
Delta
Mon 5/49:45 pm
SAN
- GSP
1 stop8h 24m
Delta
Deal found 2/1![Delta logo]()
$393
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:21 pm
GSP
- SAN
1 stop9h 04m
Delta
Sat 5/26:15 am
SAN
- GSP
1 stop7h 26m
Delta
Deal found 2/1![Delta logo]()
$393
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:40 am
GSP
- SAN
1 stop7h 31m
Delta
Thu 3/52:15 pm
SAN
- GSP
1 stop6h 28m
Delta
Deal found 1/31![Delta logo]()
$412
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:08 pm
GSP
- SAN
1 stop8h 31m
Delta
Fri 5/110:30 pm
SAN
- GSP
1 stop7h 39m
Delta
Deal found 2/1![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:21 pm
GSP
- SAN
1 stop9h 04m
Delta
Fri 5/19:45 pm
SAN
- GSP
1 stop8h 24m
Delta
Deal found 2/1![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:21 pm
GSP
- SAN
1 stop9h 04m
Delta
Sun 5/39:45 pm
SAN
- GSP
1 stop8h 24m
Delta
Deal found 2/1![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:30 am
GSP
- SAN
1 stop7h 28m
Delta
Tue 4/710:30 pm
SAN
- GSP
1 stop7h 56m
Delta
Deal found 2/1![Delta logo]()
$420
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated February 2, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated February 2, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:30 pm
GSP
- SAN
1 stop9h 50m
Southwest
Tue 2/247:40 pm
SAN
- GSP
2 stops12h 00m
Southwest
Deal found 1/31![Southwest logo]()
$433
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:40 am
GSP
- SAN
1 stop7h 21m
Delta
Tue 3/311:16 am
SAN
- GSP
1 stop6h 03m
Delta
Deal found 1/31![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:00 pm
GSP
- SAN
1 stop6h 51m
Delta
Thu 3/510:20 pm
SAN
- GSP
1 stop7h 45m
Delta
Deal found 1/31![Delta logo]()
$412
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:00 pm
GSP
- SAN
1 stop6h 51m
Delta
Sat 3/76:30 am
SAN
- GSP
1 stop8h 01m
Delta
Deal found 1/31![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:00 pm
GSP
- SAN
1 stop8h 35m
Delta
Wed 3/43:20 pm
SAN
- GSP
2 stops14h 45m
Delta
Deal found 1/31![Delta logo]()
$456
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:40 am
GSP
- SAN
1 stop7h 21m
Delta
Tue 3/312:00 pm
SAN
- GSP
1 stop7h 24m
Delta
Deal found 1/31![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:40 am
GSP
- SAN
1 stop7h 21m
Delta
Thu 3/510:20 pm
SAN
- GSP
1 stop7h 45m
Delta
Deal found 1/31![Delta logo]()
$463
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:26 pm
GSP
- SAN
1 stop8h 57m
American Airlines
Mon 3/26:20 am
SAN
- GSP
1 stop10h 26m
American Airlines
Deal found 2/1![American Airlines logo]()
$466
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:30 am
GSP
- SAN
1 stop10h 00m
Southwest
Thu 3/510:50 am
SAN
- GSP
2 stops8h 55m
Southwest
Deal found 1/31![Southwest logo]()
$468
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:43 pm
GSP
- SAN
3 stops29h 31m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$133
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:40 am
GSP
- SAN
1 stop7h 12m
Delta
Deal found 1/31![Delta logo]()
$184
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:20 am
GSP
- SAN
2 stops8h 55m
Southwest
Deal found 2/1![Southwest logo]()
$189
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:00 pm
GSP
- SAN
1 stop7h 25m
United Airlines
Deal found 2/1![United Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/1![American Airlines logo]()
$222
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:40 am
GSP
- SAN
1 stop9h 43m
American Airlines
Deal found 2/1![American Airlines logo]()
$224
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 am
GSP
- SAN
2 stops9h 27m
United Airlines
Deal found 2/1![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:18 am
GSP
- SAN
2 stops40h 53m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:51 pm
GSP
- SAN
1 stop7h 38m
American Airlines
Deal found 1/31![American Airlines logo]()
$236
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $372 (Southwest) |
One-way from | $133 (Kiwi.com) |
Popular in | February |
Cheapest in | July |
Average price | $492 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Greenville
Fly to
San Diego
Route
Depart
Return
Price
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Wed 2/25
5:40 am-10:01 am
1 stop7h 21m
San Diego
Tue 3/3
11:16 am-8:19 pm
1 stop6h 03m
$377
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Wed 4/15
12:50 pm-6:25 pm
2 stops8h 35m
San Diego
Wed 4/22
10:20 am-9:40 pm
2 stops8h 20m
$377
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sat 2/28
5:18 pm-10:48 pm
1 stop8h 30m
San Diego
Tue 3/3
12:00 pm-10:24 pm
1 stop7h 24m
$377
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 4/28
5:10 pm-9:20 pm
1 stop7h 10m
San Diego
Sat 5/2
7:40 am-9:35 pm
1 stop10h 55m
$385
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 4/28
7:30 am-2:20 pm
1 stop9h 50m
San Diego
Mon 5/4
9:45 pm-9:09 am
1 stop8h 24m
$393
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 4/30
5:21 pm-11:25 pm
1 stop9h 04m
San Diego
Sat 5/2
6:15 am-4:41 pm
1 stop7h 26m
$393
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sat 2/28
5:40 am-10:11 am
1 stop7h 31m
San Diego
Thu 3/5
2:15 pm-11:43 pm
1 stop6h 28m
$412
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 4/28
1:08 pm-6:39 pm
1 stop8h 31m
San Diego
Fri 5/1
10:30 pm-9:09 am
1 stop7h 39m
$420
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 4/30
5:21 pm-11:25 pm
1 stop9h 04m
San Diego
Fri 5/1
9:45 pm-9:09 am
1 stop8h 24m
$420
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 4/30
5:21 pm-11:25 pm
1 stop9h 04m
San Diego
Sun 5/3
9:45 pm-9:09 am
1 stop8h 24m
$420
Showing 1-10 of 20 results
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
GSP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Diego
How far ahead should I book a flight from Greenville to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Diego. Price data was last updated on January 30, 2026.
The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Diego?
Currently, March is the cheapest month in which you can book a flight from Greenville to San Diego (average of $96). Flying from Greenville to San Diego in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated February 2, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
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Alternative routes for Greenville to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Greenville to San Diego
Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$451 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$350 | Average$512 | FlexibilityNo cancel fee | On-time63% |