$192+ Cheap flights from Greenville to San Diego (GSP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
May 17 — May 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Greenville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:25 pm
GSP
- SAN
1 stop8h 14m
American Airlines
Tue 6/26:15 am
SAN
- GSP
1 stop7h 20m
American Airlines
Deal found 4/14![American Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:40 am
GSP
- SAN
2 stops10h 21m
United Airlines
Tue 5/197:00 am
SAN
- GSP
1 stop6h 59m
United Airlines
Deal found 4/14![United Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 pm
GSP
- SAN
1 stop7h 25m
United Airlines
Tue 5/199:45 pm
SAN
- GSP
1 stop9h 13m
United Airlines
Deal found 4/14![United Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:40 am
GSP
- SAN
2 stops9h 39m
United Airlines
Wed 5/1310:40 pm
SAN
- GSP
1 stop8h 07m
United Airlines
Deal found 4/15![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:25 pm
GSP
- SAN
1 stop9h 34m
American Airlines
Sat 5/309:25 pm
SAN
- GSP
1 stop7h 53m
American Airlines
Deal found 4/15![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Tue 5/1910:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 4/14![Southwest logo]()
$420
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Wed 5/136:45 am
SAN
- GSP
2 stops11h 55m
Southwest
Deal found 4/16![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
GSP
- SAN
2 stops8h 20m
Southwest
Tue 6/910:40 pm
SAN
- GSP
1 stop10h 35m
Southwest
Deal found 4/12![Southwest logo]()
$422
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Wed 6/106:45 am
SAN
- GSP
2 stops9h 15m
Southwest
Deal found 4/16![Southwest logo]()
$424
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:06 pm
GSP
- SAN
1 stop7h 29m
Delta
Wed 8/1210:30 pm
SAN
- GSP
1 stop8h 58m
Delta
Deal found 4/14![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Tue 5/2610:40 pm
SAN
- GSP
1 stop10h 30m
Southwest
Deal found 4/13![Southwest logo]()
$430
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 pm
GSP
- SAN
1 stop7h 25m
United Airlines
Tue 5/199:45 pm
SAN
- GSP
1 stop9h 13m
United Airlines
Deal found 4/14![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Tue 5/1910:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 4/14![Southwest logo]()
$420
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:43 am
GSP
- SAN
1 stop9h 18m
Delta
Sun 5/3110:15 pm
SAN
- GSP
1 stop9h 40m
Delta
Deal found 4/12![Delta logo]()
$433
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
GSP
- SAN
2 stops8h 20m
Southwest
Tue 6/910:40 pm
SAN
- GSP
1 stop10h 35m
Southwest
Deal found 4/12![Southwest logo]()
$422
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:40 am
GSP
- SAN
1 stop6h 59m
Delta
Tue 6/27:10 pm
SAN
- GSP
2 stops12h 45m
Delta
Deal found 4/12![Delta logo]()
$475
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Tue 5/269:15 am
SAN
- GSP
2 stops9h 25m
Southwest
Deal found 4/17![Southwest logo]()
$438
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
GSP
- SAN
1 stop8h 36m
Delta
Wed 5/277:10 pm
SAN
- GSP
2 stops12h 45m
Delta
Deal found 4/14![Delta logo]()
$483
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:25 am
GSP
- SAN
2 stops8h 45m
Southwest
Mon 5/1810:40 pm
SAN
- GSP
1 stop10h 30m
Southwest
Deal found 4/15![Southwest logo]()
$455
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:45 am
GSP
- SAN
2 stops8h 45m
Southwest
Tue 5/1910:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 4/14![Southwest logo]()
$468
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:25 am
GSP
- SAN
2 stops9h 15m
Southwest
Wed 5/206:45 am
SAN
- GSP
2 stops11h 55m
Southwest
Deal found 4/16![Southwest logo]()
$479
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated April 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:40 am
GSP
- SAN
2 stops9h 39m
United Airlines
Wed 5/1310:40 pm
SAN
- GSP
1 stop8h 07m
United Airlines
Deal found 4/15![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:05 pm
GSP
- SAN
1 stop7h 15m
Southwest
Wed 5/136:45 am
SAN
- GSP
2 stops11h 55m
Southwest
Deal found 4/16![Southwest logo]()
$421
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 pm
GSP
- SAN
1 stop7h 25m
United Airlines
Tue 5/199:45 pm
SAN
- GSP
1 stop9h 13m
United Airlines
Deal found 4/14![United Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:40 am
GSP
- SAN
2 stops10h 21m
United Airlines
Tue 5/197:00 am
SAN
- GSP
1 stop6h 59m
United Airlines
Deal found 4/14![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:45 am
GSP
- SAN
2 stops9h 10m
Southwest
Tue 5/1910:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Deal found 4/14![Southwest logo]()
$420
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:54 pm
GSP
- SAN
1 stop7h 05m
American Airlines
Tue 5/269:25 pm
SAN
- GSP
1 stop7h 53m
American Airlines
Deal found 4/17![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:25 pm
GSP
- SAN
1 stop9h 34m
American Airlines
Sat 5/309:25 pm
SAN
- GSP
1 stop7h 53m
American Airlines
Deal found 4/15![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Tue 5/2610:40 pm
SAN
- GSP
1 stop10h 30m
Southwest
Deal found 4/13![Southwest logo]()
$430
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:25 pm
GSP
- SAN
1 stop8h 14m
American Airlines
Tue 6/26:15 am
SAN
- GSP
1 stop7h 20m
American Airlines
Deal found 4/14![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Wed 6/106:45 am
SAN
- GSP
2 stops9h 15m
Southwest
Deal found 4/16![Southwest logo]()
$424
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 am
GSP
- SAN
1 stop6h 59m
Delta
Sun 5/3110:15 pm
SAN
- GSP
1 stop9h 40m
Delta
Deal found 4/14![Delta logo]()
$433
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:20 am
GSP
- SAN
1 stop8h 53m
American Airlines
Deal found 4/13![American Airlines logo]()
$192
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:45 am
GSP
- SAN
2 stops8h 25m
Southwest
Deal found 4/13![Southwest logo]()
$197
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:25 pm
GSP
- SAN
1 stop7h 40m
Southwest
Deal found 4/13![Southwest logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:43 pm
GSP
- SAN
3 stops50h 48m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/213:17 pm
GSP
- SAN
3 stops59h 36m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$221
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:45 am
GSP
- SAN
2 stops9h 20m
Southwest
Deal found 4/15![Southwest logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:18 pm
GSP
- SAN
3 stops43h 59m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:12 pm
GSP
- SAN
3 stops30h 40m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$271
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $383 (American Airlines) |
One-way from | $192 (American Airlines) |
Popular in | April |
Cheapest in | January |
Average price | $541 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sat 5/9
5:00 pm-9:25 pm
1 stop7h 25m
San Diego
Tue 5/19
9:45 pm-9:58 am
1 stop9h 13m
$391
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 5/12
6:45 am-12:55 pm
2 stops9h 10m
San Diego
Tue 5/19
10:20 am-9:40 pm
2 stops8h 20m
$420
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Mon 6/1
6:25 am-11:45 am
2 stops8h 20m
San Diego
Tue 6/9
10:40 pm-12:15 pm
1 stop10h 35m
$422
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 5/28
11:43 am-6:01 pm
1 stop9h 18m
San Diego
Sun 5/31
10:15 pm-10:55 am
1 stop9h 40m
$433
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Fri 5/22
6:25 pm-11:05 pm
1 stop7h 40m
San Diego
Tue 5/26
9:15 am-9:40 pm
2 stops9h 25m
$438
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 5/14
6:25 am-12:10 pm
2 stops8h 45m
San Diego
Mon 5/18
10:40 pm-12:10 pm
1 stop10h 30m
$455
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sat 5/9
10:45 am-4:30 pm
2 stops8h 45m
San Diego
Tue 5/19
10:20 am-9:40 pm
2 stops8h 20m
$468
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Wed 5/27
5:40 am-9:39 am
1 stop6h 59m
San Diego
Tue 6/2
7:10 pm-10:55 am
2 stops12h 45m
$475
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Thu 5/14
6:25 am-12:40 pm
2 stops9h 15m
San Diego
Wed 5/20
6:45 am-9:40 pm
2 stops11h 55m
$479
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sat 5/9
5:40 am-11:16 am
1 stop8h 36m
San Diego
Wed 5/27
7:10 pm-10:55 am
2 stops12h 45m
$483
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
GSP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Diego
How far ahead should I book a flight from Greenville to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Diego. Price data was last updated on April 10, 2026.
The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Diego?
Currently, January is the cheapest month in which you can book a flight from Greenville to San Diego (average of $367). Flying from Greenville to San Diego in April is currently the most expensive (average of $541). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 17, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Greenville
Popular flights
San Diego flight routes
Alternative routes for Greenville to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to San Diego by cabin class
Find flights from Greenville to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and San Diego flights
Browse other Greenville and San Diego flight options. Last updated on April 17, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
Top 4 airlines flying from Greenville to San Diego
Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$426 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$305 | Average$516 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$477 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$312 | Average$470 | FlexibilityNo cancel fee | On-time71% |