$230+ Cheap flights from Illinois to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
May 25 — Jun 11
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Illinois to Panama City
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Cheapest flights from Illinois to Panama CityExplore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:05 am
ORD
- PTY
2 stops19h 30m
Multiple Airlines
Tue 5/125:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$440
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:05 am
ORD
- PTY
2 stops35h 55m
Multiple Airlines
Sat 6/64:25 am
PTY
- ORD
2 stops18h 50m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$470
This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:20 am
ORD
- PTY
3 stops16h 35m
Multiple Airlines
Mon 5/184:25 am
PTY
- ORD
2 stops19h 31m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$483
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Sun 6/75:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$487
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Tue 5/195:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:14 am
STL
- PTY
1 stop8h 00m
United Airlines
Tue 7/143:30 pm
PTY
- STL
1 stop18h 37m
United Airlines
Deal found 4/21![United Airlines logo]()
$525
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Sun 5/315:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$537
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:33 pm
STL
- PTY
2 stops20h 41m
United Airlines
Mon 8/103:30 pm
PTY
- STL
1 stop30h 46m
United Airlines
Deal found 4/20![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:48 pm
STL
- PTY
1 stop11h 16m
United Airlines
Wed 5/277:55 am
PTY
- STL
1 stop9h 47m
United Airlines
Deal found 4/23![United Airlines logo]()
$542
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:30 am
ORD
- PTY
2 stops32h 30m
Multiple Airlines
Thu 5/2810:10 am
PTY
- ORD
3 stops33h 54m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$542
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:59 pm
ORD
- PTY
3 stops27h 36m
Multiple Airlines
Fri 6/54:25 am
PTY
- ORD
2 stops18h 50m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$547
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:05 am
STL
- PTY
1 stop7h 32m
United Airlines
Sat 10/249:45 am
PTY
- STL
1 stop11h 39m
United Airlines
Deal found 4/22![United Airlines logo]()
$559
Best flights from Illinois to Panama CityDiscover carefully curated flight deals from Illinois to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
Discover carefully curated flight deals from Illinois to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:23 am
STL
- PTY
2 stops18h 41m
United Airlines
Tue 7/1410:00 am
PTY
- STL
2 stops22h 41m
United Airlines
Deal found 4/24![United Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:12 pm
STL
- PTY
2 stops18h 02m
American Airlines
Thu 6/111:14 pm
PTY
- STL
2 stops19h 17m
American Airlines
Deal found 4/20![American Airlines logo]()
$629
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:27 pm
MDW
- PTY
1 stop8h 07m
Multiple Airlines
Tue 6/910:25 am
PTY
- MDW
2 stops11h 46m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$662
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:01 am
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Mon 10/127:20 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Deal found 4/23![Copa Airlines logo]()
$687
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 am
ORD
- PTY
1 stop7h 26m
Delta
Mon 10/52:21 pm
PTY
- ORD
1 stop9h 36m
Delta
Deal found 4/24![Delta logo]()
$702
This Avianca deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/711:20 pm
ORD
- PTY
1 stop14h 55m
Avianca
Sun 6/144:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 4/23![Avianca logo]()
$709
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:13 pm
STL
- PTY
2 stops14h 51m
United Airlines
Wed 5/277:55 am
PTY
- STL
1 stop9h 47m
United Airlines
Deal found 4/23![United Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:33 pm
STL
- PTY
2 stops20h 41m
United Airlines
Fri 7/2410:55 pm
PTY
- STL
2 stops13h 12m
United Airlines
Deal found 4/22![United Airlines logo]()
$546
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:20 pm
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Mon 9/147:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$687
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:30 am
ORD
- PTY
1 stop7h 43m
Delta
Mon 8/242:28 pm
PTY
- ORD
2 stops17h 28m
Delta
Deal found 4/20![Delta logo]()
$706
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:48 pm
STL
- PTY
1 stop11h 16m
United Airlines
Sat 6/67:55 am
PTY
- STL
1 stop14h 50m
United Airlines
Deal found 4/20![United Airlines logo]()
$603
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Mon 8/247:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 am
MDW
- PTY
2 stops13h 20m
Multiple Airlines
Wed 6/1710:26 am
PTY
- MDW
1 stop11h 45m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$765
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 am
ORD
- PTY
1 stop7h 26m
Delta
Tue 9/222:21 pm
PTY
- ORD
2 stops17h 35m
Delta
Deal found 4/24![Delta logo]()
$706
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:34 pm
EVV
- PTY
2 stops19h 40m
American Airlines
Sun 6/141:14 pm
PTY
- EVV
2 stops23h 07m
American Airlines
Deal found 4/23![American Airlines logo]()
$832
This Copa Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Tue 7/76:25 pm
PTY
- ORD
Nonstop5h 36m
Copa Airlines
Deal found 4/24![Copa Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:15 am
STL
- PTY
1 stop12h 22m
United Airlines
Thu 10/83:30 pm
PTY
- STL
2 stops17h 07m
United Airlines
Deal found 4/21![United Airlines logo]()
$632
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Sat 6/610:26 am
PTY
- MDW
1 stop11h 36m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$783
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:36 pm
MDW
- PTY
2 stops18h 33m
Delta
Wed 6/102:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 4/23![Delta logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Wed 6/1710:10 pm
PTY
- ORD
Nonstop5h 50m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:14 am
STL
- PTY
1 stop9h 58m
United Airlines
Thu 8/133:30 pm
PTY
- STL
2 stops17h 07m
United Airlines
Deal found 4/21![United Airlines logo]()
$632
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:04 pm
MDW
- PTY
1 stop8h 30m
Multiple Airlines
Mon 8/179:33 pm
PTY
- MDW
2 stops37h 36m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$820
This Copa Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Wed 7/158:10 am
PTY
- ORD
Nonstop5h 47m
Copa Airlines
Deal found 4/24![Copa Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:30 pm
STL
- PTY
1 stop19h 44m
United Airlines
Mon 8/103:30 pm
PTY
- STL
1 stop30h 46m
United Airlines
Deal found 4/21![United Airlines logo]()
$649
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:11 pm
MDW
- PTY
1 stop19h 48m
Delta
Fri 7/32:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 4/20![Delta logo]()
$807
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:05 am
MDW
- PTY
1 stop7h 04m
Delta
Wed 6/172:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 4/22![Delta logo]()
$819
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
STL
- PTY
1 stop12h 37m
United Airlines
Sun 5/177:55 am
PTY
- STL
1 stop14h 35m
United Airlines
Deal found 4/20![United Airlines logo]()
$701
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:22 pm
MDW
- PTY
2 stops23h 28m
Delta
Sun 5/312:15 pm
PTY
- MDW
2 stops22h 27m
Delta
Deal found 4/22![Delta logo]()
$823
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
STL
- PTY
1 stop12h 37m
United Airlines
Tue 5/263:30 pm
PTY
- STL
1 stop18h 37m
United Airlines
Deal found 4/19![United Airlines logo]()
$708
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:22 pm
MDW
- PTY
2 stops23h 28m
Delta
Sun 6/72:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 4/22![Delta logo]()
$823
Last-minute flights from Illinois to Panama CityDiscover last-minute flight deals from Illinois to Panama City. Data last updated April 25, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Panama City. Data last updated April 25, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:05 am
ORD
- PTY
2 stops19h 30m
Multiple Airlines
Tue 5/125:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$440
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Sun 5/104:25 am
PTY
- ORD
2 stops18h 50m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$572
This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:20 am
ORD
- PTY
3 stops16h 35m
Multiple Airlines
Mon 5/184:25 am
PTY
- ORD
2 stops19h 31m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$483
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Tue 5/195:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$494
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Tue 5/265:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$577
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:48 pm
STL
- PTY
1 stop11h 16m
United Airlines
Wed 5/277:55 am
PTY
- STL
1 stop9h 47m
United Airlines
Deal found 4/23![United Airlines logo]()
$542
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:30 am
ORD
- PTY
2 stops32h 30m
Multiple Airlines
Thu 5/2810:10 am
PTY
- ORD
3 stops33h 54m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:12 pm
STL
- PTY
2 stops18h 02m
American Airlines
Wed 6/101:14 pm
PTY
- STL
1 stop9h 44m
American Airlines
Deal found 4/22![American Airlines logo]()
$629
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:05 am
ORD
- PTY
2 stops28h 10m
Multiple Airlines
Sun 5/315:55 pm
PTY
- ORD
2 stops29h 20m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$537
This KAYAK deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
STL
- PTY
1 stop13h 31m
Copa Airlines
Tue 6/23:30 pm
PTY
- STL
1 stop18h 37m
Copa Airlines
Deal found 4/24![Copa Airlines logo]()
$574
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
STL
- PTY
1 stop6h 50m
Delta
Wed 6/32:15 pm
PTY
- STL
1 stop22h 05m
Delta
Deal found 4/23![Delta logo]()
$587
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:48 pm
STL
- PTY
1 stop11h 16m
United Airlines
Sat 6/67:55 am
PTY
- STL
1 stop14h 50m
United Airlines
Deal found 4/20![United Airlines logo]()
$603
One-way flights from Illinois to Panama CitySearch for one-way flight options from Illinois to Panama City. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
Search for one-way flight options from Illinois to Panama City. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
STL
- PTY
2 stops12h 37m
United Airlines
Deal found 4/22![United Airlines logo]()
$230
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:12 pm
STL
- PTY
2 stops18h 02m
American Airlines
Deal found 4/21![American Airlines logo]()
$235
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:48 pm
STL
- PTY
1 stop11h 16m
United Airlines
Deal found 4/22![United Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
STL
- PTY
2 stops22h 04m
United Airlines
Deal found 4/22![United Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:52 pm
ORD
- PTY
2 stops36h 14m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:49 pm
ORD
- PTY
2 stops29h 31m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
STL
- PTY
1 stop6h 50m
Delta
Deal found 4/22![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:52 pm
ORD
- PTY
3 stops24h 50m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/319:24 am
STL
- PTY
2 stops26h 50m
American Airlines
Deal found 4/22![American Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:59 am
ORD
- PTY
3 stops22h 36m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:01 pm
STL
- PTY
1 stop17h 49m
Delta
Deal found 4/22![Delta logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
MDW
- PTY
3 stops56h 55m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$321
Find flight deals from Illinois to Panama City
Keep the following information in mind while searching for Illinois to Panama City flight deals. Data was last updated April 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $470 (Mytrip) |
One-way from | $230 (United Airlines) |
Popular in | May |
Cheapest in | September |
Average price | $581 |
Good round-trip deal | $479 or less |
Good one-way deal | $202 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Illinois to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Tue 7/7
9:23 am-4:04 am
2 stops18h 41m
Panama City Tocumen Intl
Tue 7/14
10:00 am-8:41 am
2 stops22h 41m
$529
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sat 5/23
1:13 pm-4:04 am
2 stops14h 51m
Panama City Tocumen Intl
Wed 5/27
7:55 am-5:42 pm
1 stop9h 47m
$546
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Mon 7/6
5:33 pm-2:14 pm
2 stops20h 41m
Panama City Tocumen Intl
Fri 7/24
10:55 pm-12:07 pm
2 stops13h 12m
$546
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Fri 5/29
4:48 pm-4:04 am
1 stop11h 16m
Panama City Tocumen Intl
Sat 6/6
7:55 am-10:45 pm
1 stop14h 50m
$603
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Thu 6/4
6:12 pm-12:14 pm
2 stops18h 02m
Panama City Tocumen Intl
Thu 6/11
1:14 pm-8:31 am
2 stops19h 17m
$629
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Mon 10/5
6:15 am-6:37 pm
1 stop12h 22m
Panama City Tocumen Intl
Thu 10/8
3:30 pm-8:37 am
2 stops17h 07m
$632
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Wed 8/5
6:14 am-4:12 pm
1 stop9h 58m
Panama City Tocumen Intl
Thu 8/13
3:30 pm-8:37 am
2 stops17h 07m
$632
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sun 8/2
6:30 pm-2:14 pm
1 stop19h 44m
Panama City Tocumen Intl
Mon 8/10
3:30 pm-10:16 pm
1 stop30h 46m
$649
ChicagoPanama City
MDW - PTY
MDWPTY
Chicago Midway
Tue 6/2
12:27 pm-8:34 pm
1 stop8h 07m
Panama City Tocumen Intl
Tue 6/9
10:25 am-10:11 pm
2 stops11h 46m
$662
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Thu 10/8
8:01 am-1:22 pm
Nonstop5h 21m
Panama City Tocumen Intl
Mon 10/12
7:20 pm-12:57 am
Nonstop5h 37m
$687
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Illinois to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.
ORD-PTY
STL-PTY
MDW-PTY
EVV-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Panama City
USIL-PTY
ORD-PTY
STL-PTY
MDW-PTY
EVV-PTY
How far ahead should I book a flight from Illinois to Panama City?
The best time to book flights from Illinois to Panama City is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Illinois to Panama City?
Currently, February is the cheapest month in which you can book a flight from Illinois to Panama City (average of $102). Flying from Illinois to Panama City in September is currently the most expensive (average of $450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to PTY?
Find hourly flight availability from Illinois to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2026.
A simple way to save on the total cost of your ticket is to fly from Illinois to Panama City in the evening. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the morning.
What is the cheapest day to fly from Illinois to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Panama City. Price data was last updated on April 18, 2026.
Travelers seeking maximum savings on their Illinois to Panama City flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to Panama City
Explore weekly flight availability from Illinois to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 25, 2026.
The most flights from USIL to PTY are scheduled on a Tuesday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Illinois to Panama City?
Related info for your journey
Find useful and relevant information for your journey from Illinois to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Panama City flight routes
Popular flights
Top destinations
Alternative routes for Illinois to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to Panama City by cabin class
Find flights from Illinois to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and Panama City flights
Browse other Illinois and Panama City flight options. Last updated on April 25, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Illinois to Panama City flights
Consider these flights traveling from Illinois to Panama City.
Top 5 airlines flying from Illinois to Panama City
Discover the top 5 airlines that operate flights from Illinois to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$302 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$453 | Average$595 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$479 | Average$779 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$479 | Average$642 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$601 | Average$721 | FlexibilityNo cancel fee | On-time71% |