$296+ Cheap flights from Illinois to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
Nov 24 — Dec 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Illinois to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Illinois to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Illinois to Panama CityExplore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/93:13 pm -
1 stop17h 25m
Deal found 10/21![American Airlines logo]()
$697
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:00 am -
2 stops13h 38m
Tue 12/1510:00 am -
2 stops13h 59m
Deal found 10/24![United Airlines logo]()
$717
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:13 am -
2 stops23h 57m
Sat 12/510:05 am -
2 stops24h 50m
Deal found 10/22![Multiple Airlines logo]()
$725
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:55 am -
2 stops16h 25m
Fri 11/202:30 am -
2 stops22h 04m
Deal found 10/20![Multiple Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Fri 12/43:13 pm -
1 stop17h 42m
Deal found 10/21![American Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:31 pm -
2 stops23h 14m
Thu 12/310:00 am -
2 stops24h 55m
Deal found 10/22![United Airlines logo]()
$742
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:07 pm -
2 stops21h 27m
Thu 12/33:13 pm -
2 stops25h 21m
Deal found 10/22![American Airlines logo]()
$747
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:25 am -
2 stops26h 09m
Wed 12/23:13 pm -
2 stops26h 18m
Deal found 10/22![American Airlines logo]()
$747
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:05 am -
1 stop11h 56m
Fri 12/117:17 pm -
1 stop10h 26m
Deal found 10/20![Multiple Airlines logo]()
$750
This FlightHub deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:30 pm -
1 stop9h 40m
Fri 12/44:10 pm -
1 stop29h 20m
Deal found 10/25![Avianca logo]()
$751
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:31 pm -
2 stops28h 31m
Tue 12/14:41 pm -
2 stops21h 04m
Deal found 10/22![United Airlines logo]()
$758
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:30 am -
2 stops10h 49m
Sat 12/124:00 pm -
2 stops16h 20m
Deal found 10/21![Multiple Airlines logo]()
$759
Best flights from Illinois to Panama CityDiscover carefully curated flight deals from Illinois to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Illinois to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:00 am -
2 stops13h 38m
Tue 12/1510:00 am -
2 stops13h 59m
Deal found 10/24![United Airlines logo]()
$717
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:13 pm -
Nonstop5h 25m
Sun 1/317:28 pm -
Nonstop5h 43m
Deal found 10/22![Copa Airlines logo]()
$777
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/256:00 am -
1 stop6h 55m
Sun 2/283:20 pm -
1 stop7h 50m
Deal found 10/20![Delta logo]()
$792
This KAYAK deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:29 pm -
2 stops14h 57m
Wed 1/202:26 pm -
1 stop11h 39m
Deal found 10/23![American Airlines logo]()
$828
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
2 stops14h 02m
Tue 12/14:41 pm -
2 stops23h 29m
Deal found 10/22![United Airlines logo]()
$742
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/256:00 am -
1 stop6h 55m
Tue 3/23:20 pm -
1 stop7h 50m
Deal found 10/21![Delta logo]()
$792
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/142:13 pm -
Nonstop5h 25m
Sat 1/167:28 pm -
Nonstop5h 39m
Deal found 10/21![Copa Airlines logo]()
$805
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:31 pm -
2 stops23h 14m
Wed 12/24:41 pm -
2 stops21h 04m
Deal found 10/22![United Airlines logo]()
$742
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/152:13 pm -
Nonstop5h 25m
Mon 1/187:28 pm -
Nonstop5h 39m
Deal found 10/21![Copa Airlines logo]()
$805
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/19:30 am -
2 stops11h 15m
Tue 1/58:00 am -
1 stop9h 25m
Deal found 10/21![Delta logo]()
$825
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:31 pm -
2 stops23h 14m
Sat 12/58:55 am -
2 stops13h 02m
Deal found 10/22![United Airlines logo]()
$776
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
1 stop6h 55m
Sat 1/233:20 pm -
1 stop7h 50m
Deal found 10/23![Delta logo]()
$840
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:17 pm -
Nonstop5h 24m
Sat 12/127:28 pm -
Nonstop5h 43m
Deal found 10/21![Copa Airlines logo]()
$853
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
2 stops14h 02m
Fri 12/48:55 am -
2 stops15h 04m
Deal found 10/22![United Airlines logo]()
$776
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:17 pm -
Nonstop5h 24m
Mon 12/78:06 am -
Nonstop5h 40m
Deal found 10/23![Copa Airlines logo]()
$853
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:01 am -
1 stop7h 06m
Thu 11/193:29 pm -
1 stop8h 02m
Deal found 10/23![Delta logo]()
$853
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:28 pm -
1 stop20h 34m
Tue 11/173:29 pm -
1 stop8h 02m
Deal found 10/22![Delta logo]()
$865
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
1 stop6h 55m
Sat 1/301:40 pm -
1 stop9h 30m
Deal found 10/20![Delta logo]()
$866
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:00 am -
1 stop14h 02m
Thu 11/54:41 pm -
1 stop17h 30m
Deal found 10/22![United Airlines logo]()
$973
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:13 pm -
Nonstop5h 24m
Mon 11/97:28 pm -
Nonstop5h 43m
Deal found 10/23![Copa Airlines logo]()
$982
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:00 am -
1 stop7h 04m
Tue 2/23:29 pm -
1 stop9h 26m
Deal found 10/25![Delta logo]()
$866
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:35 am -
Nonstop5h 26m
Thu 11/57:28 pm -
Nonstop5h 43m
Deal found 10/22![Copa Airlines logo]()
$1,014
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 03m
Sat 12/123:29 pm -
1 stop8h 25m
Deal found 10/22![Delta logo]()
$868
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:35 am -
Nonstop5h 21m
Sun 11/17:28 pm -
Nonstop5h 43m
Deal found 10/22![Copa Airlines logo]()
$1,014
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:01 am -
1 stop7h 01m
Tue 11/173:29 pm -
1 stop8h 02m
Deal found 10/25![Delta logo]()
$881
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:01 am -
1 stop7h 01m
Thu 11/193:29 pm -
1 stop8h 02m
Deal found 10/25![Delta logo]()
$881
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:01 am -
1 stop7h 01m
Tue 11/173:29 pm -
1 stop8h 02m
Deal found 10/25![Delta logo]()
$908
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:01 am -
1 stop7h 01m
Wed 11/253:29 pm -
1 stop8h 02m
Deal found 10/25![Delta logo]()
$912
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:28 pm -
1 stop20h 34m
Thu 11/193:29 pm -
1 stop8h 02m
Deal found 10/22![Delta logo]()
$915
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:01 am -
1 stop7h 03m
Mon 12/73:29 pm -
1 stop7h 57m
Deal found 10/23![Delta logo]()
$921
Last-minute flights from Illinois to Panama CityDiscover last-minute flight deals from Illinois to Panama City. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Panama City. Data last updated October 25, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:30 pm -
1 stop9h 40m
Fri 11/62:30 am -
1 stop19h 00m
Deal found 10/23![Avianca logo]()
$764
This Avianca deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:30 pm -
1 stop9h 40m
Fri 11/62:30 am -
1 stop19h 00m
Deal found 10/23![Avianca logo]()
$763
This FlightHub deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:30 pm -
1 stop9h 40m
Fri 12/44:10 pm -
1 stop29h 20m
Deal found 10/25![Avianca logo]()
$751
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:55 am -
2 stops16h 25m
Fri 11/202:30 am -
2 stops22h 04m
Deal found 10/20![Multiple Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/93:13 pm -
1 stop17h 25m
Deal found 10/21![American Airlines logo]()
$697
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:31 pm -
2 stops23h 14m
Thu 12/310:00 am -
2 stops24h 55m
Deal found 10/22![United Airlines logo]()
$742
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:31 pm -
2 stops23h 14m
Mon 11/304:41 pm -
2 stops18h 14m
Deal found 10/22![United Airlines logo]()
$759
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:07 pm -
2 stops21h 27m
Wed 12/23:13 pm -
2 stops23h 35m
Deal found 10/22![American Airlines logo]()
$747
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:25 am -
2 stops26h 09m
Wed 12/23:13 pm -
2 stops26h 18m
Deal found 10/22![American Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:31 pm -
2 stops28h 31m
Tue 12/14:41 pm -
2 stops21h 04m
Deal found 10/22![United Airlines logo]()
$758
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:13 am -
2 stops23h 57m
Sat 12/510:05 am -
2 stops24h 50m
Deal found 10/22![Multiple Airlines logo]()
$725
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Fri 12/43:13 pm -
1 stop17h 42m
Deal found 10/21![American Airlines logo]()
$737
One-way flights from Illinois to Panama CitySearch for one-way flight options from Illinois to Panama City. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Illinois to Panama City. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:10 pm -
1 stop18h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$296
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/48:00 pm -
1 stop16h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:10 pm -
1 stop18h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:10 pm -
2 stops17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/28:29 pm -
1 stop18h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3112:04 am -
1 stop12h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:10 pm -
1 stop18h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/211:18 pm -
2 stops16h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/201:18 pm -
2 stops16h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/181:18 pm -
2 stops18h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/191:18 pm -
2 stops18h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/221:18 pm -
2 stops17h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$386
Find flight deals from Illinois to Panama City
Keep the following information in mind while searching for Illinois to Panama City flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $697 (American Airlines) |
One-way from | $296 (American Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $863 |
Good round-trip deal | $581 or less |
Good one-way deal | $295 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Illinois to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 3/5
6:00 am-3:30 pm
1 stop8h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$301
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Thu 1/21
1:18 pm-6:35 am
2 stops16h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$363
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 1/7
6:20 am-8:29 pm
2 stops13h 09m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$365
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Wed 1/20
1:18 pm-6:35 am
2 stops16h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$367
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Fri 1/22
1:18 pm-7:49 am
2 stops17h 31m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$386
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Wed 12/2
10:21 am-8:19 pm
2 stops32h 58m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$411
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Thu 2/4
8:47 pm-6:35 am
3 stops32h 48m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$463
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Mon 12/28
8:35 pm-4:01 pm
3 stops42h 26m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$487
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 12/31
7:25 am-6:00 am
2 stops21h 35m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$496
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Mon 11/2
6:17 pm-6:28 am
3 stops35h 11m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$506
Showing 1-10 of 47 resultsSorted by cheapest first
Best time to book a flight from Illinois to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.
ORD-PTY
MDW-PTY
MLI-PTY
BMI-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Panama City
USIL-PTY
ORD-PTY
MDW-PTY
MLI-PTY
BMI-PTY
What is the cheapest month to book a flight from Illinois to Panama City?
Currently, April is the cheapest month in which you can book a flight from Illinois to Panama City (average of $584). Flying from Illinois to Panama City in December is currently the most expensive (average of $1,031). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to PTY?
Find hourly flight availability from Illinois to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
A simple way to save on the total cost of your ticket is to fly from Illinois to Panama City in the evening. If you’re flexible enough to do this you can expect to save up to 14% on your trip compared to booking a flight in the morning.
How much does it cost to fly round-trip from Illinois to Panama City?
Airfare is below average for this route at the moment.
Illinois to Panama City flights typically cost between $714 and $941 in November.The cheapest round-trip price found within the last 5 days was $697 on American Airlines (Nov 18-Dec 9).
How far ahead should I book a flight from Illinois to Panama City?
The best time to book flights from Illinois to Panama City is 30 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Illinois to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Panama City. Price data was last updated on October 24, 2026.
Travelers seeking maximum savings on their Illinois to Panama City flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Illinois to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Panama City flight routes
Popular flights
Top destinations
Alternative routes for Illinois to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to Panama City by cabin class
Find flights from Illinois to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and Panama City flights
Browse other Illinois and Panama City flight options. Last updated on October 25, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Illinois to Panama City flights
Consider these flights traveling from Illinois to Panama City.
Top 4 airlines flying from Illinois to Panama City
Discover the top 4 airlines that operate flights from Illinois to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$316 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$564 | Average$717 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$577 | Average$804 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$596 | Average$805 | FlexibilityNo cancel fee | On-time71% |