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Panama City

$275+ Cheap flights from Illinois to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
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Cheap flight deals from Illinois to Panama City

Cheapest flights from Illinois to Panama City
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:01 am
STL
-
PTY
1 stop13h 30m
United Airlines
Wed 7/159:45 am
PTY
-
STL
1 stop13h 59m
United Airlines
Deal found 6/8$575
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:59 pm
STL
-
PTY
2 stops20h 15m
United Airlines
Mon 8/103:30 pm
PTY
-
STL
2 stops20h 32m
United Airlines
Deal found 6/12$579
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am
STL
-
PTY
1 stop12h 31m
United Airlines
Wed 8/2610:55 pm
PTY
-
STL
1 stop24h 43m
United Airlines
Deal found 6/9$585
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:10 am
STL
-
PTY
1 stop7h 27m
United Airlines
Tue 8/43:30 pm
PTY
-
STL
1 stop18h 37m
United Airlines
Deal found 6/8$592
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:35 pm
STL
-
PTY
2 stops20h 19m
American Airlines
Sun 1/314:46 pm
PTY
-
STL
2 stops19h 19m
American Airlines
Deal found 6/11$601
This Trip.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
MDW
-
PTY
3 stops27h 15m
Multiple Airlines
Sun 8/233:10 pm
PTY
-
MDW
3 stops22h 57m
Multiple Airlines
Deal found 6/10$603
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:11 pm
STL
-
PTY
2 stops19h 28m
American Airlines
Fri 8/141:39 pm
PTY
-
STL
2 stops19h 45m
American Airlines
Deal found 6/8$606
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am
STL
-
PTY
1 stop12h 31m
United Airlines
Sat 9/2610:00 am
PTY
-
STL
1 stop10h 16m
United Airlines
Deal found 6/12$609
This Mytrip deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:40 am
ORD
-
PTY
3 stops24h 15m
Multiple Airlines
Mon 8/315:55 pm
PTY
-
ORD
3 stops35h 57m
Multiple Airlines
Deal found 6/8$642
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:40 am
ORD
-
PTY
3 stops31h 35m
Multiple Airlines
Mon 9/75:55 pm
PTY
-
ORD
3 stops35h 57m
Multiple Airlines
Deal found 6/9$683
This Mytrip deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:40 am
ORD
-
PTY
3 stops24h 15m
Multiple Airlines
Mon 9/73:10 pm
PTY
-
ORD
1 stop30h 10m
Multiple Airlines
Deal found 6/8$718
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:53 am
ORD
-
PTY
3 stops30h 22m
Multiple Airlines
Sun 9/65:30 am
PTY
-
ORD
3 stops24h 22m
Multiple Airlines
Deal found 6/10$724

Find flight deals from Illinois to Panama City

Keep the following information in mind while searching for Illinois to Panama City flight deals. Data was last updated June 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$575
(United Airlines)

One-way from

$275
(Flightnetwork)

Popular in

October

Cheapest in

February

Average price

$700

Good round-trip deal

$515 or less

Good one-way deal

$270 or less
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
Search Deals
From Illinois to Panama City Tocumen Intl
Search Deals
One-way flight from Illinois to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Illinois to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Illinois to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Illinois to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 7/8

11:10 am-6:37 pm

1 stop7h 27m

Panama City Tocumen Intl

Wed 7/15

7:55 am-10:45 pm

1 stop14h 50m

$575

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 7/22

6:14 am-6:37 pm

1 stop12h 23m

Panama City Tocumen Intl

Wed 7/29

3:30 pm-10:07 am

1 stop18h 37m

$575

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 8/11

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

Thu 8/13

3:30 pm-12:02 pm

2 stops20h 32m

$579

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 7/23

6:00 am-4:04 am

2 stops22h 04m

Panama City Tocumen Intl

Wed 7/29

10:00 am-8:39 am

2 stops22h 39m

$579

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 8/25

8:00 am-7:31 pm

2 stops11h 31m

Panama City Tocumen Intl

Wed 8/26

10:55 pm-12:02 pm

2 stops13h 07m

$579

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 8/2

5:59 pm-4:12 pm

2 stops22h 13m

Panama City Tocumen Intl

Mon 8/10

3:30 pm-12:02 pm

2 stops20h 32m

$579

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 8/18

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Fri 8/21

2:20 pm-11:58 pm

1 stop9h 38m

$592

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/16

11:15 am-6:37 pm

1 stop7h 22m

Panama City Tocumen Intl

Sat 9/19

9:45 am-11:38 pm

1 stop13h 53m

$592

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/8

8:01 am-1:22 pm

Nonstop5h 21m

Panama City Tocumen Intl

Sun 10/11

7:20 pm-12:57 am

Nonstop5h 37m

$737

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 11/2

7:35 am-2:01 pm

Nonstop5h 26m

Panama City Tocumen Intl

Mon 11/9

7:28 pm-12:11 am

Nonstop5h 43m

$737

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/8

Showing 1-10 of 51 resultsSorted by cheapest first
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Best time to book a flight from Illinois to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Panama City

What is the cheapest month to book a flight from Illinois to Panama City?

Currently, February is the cheapest month in which you can book a flight from Illinois to Panama City (average of $102). Flying from Illinois to Panama City in June is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to PTY?

Find hourly flight availability from Illinois to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2026.

A simple way to save on the total cost of your ticket is to fly from Illinois to Panama City in the evening. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight in the morning.

Weekly flight availability from Illinois to Panama City

Explore weekly flight availability from Illinois to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2026.

The most flights from USIL to PTY are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).

How much does it cost to fly round-trip from Illinois to Panama City?

How far ahead should I book a flight from Illinois to Panama City?

The best time to book flights from Illinois to Panama City is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest day to fly from Illinois to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Illinois to Panama City. Price data was last updated on June 8, 2026.

Travelers seeking maximum savings on their Illinois to Panama City flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Illinois to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Illinois?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Illinois to Panama City.

  • How long is the flight from Illinois to Panama City?

    Departing from Illinois to Panama City will take you 5h 21m. There are 2330 mi between Illinois and Panama City. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Illinois to Panama City?

    While some choose either Chicago Midway - Panama City Tocumen Intl or Lambert-St Louis - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Illinois to Panama City.

  • What are the most reliable airlines from Illinois to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Panama City on time: EVA Air (89%), Copa Airlines (88%), United Airlines (88%).

  • What are the cheapest flights from Illinois to Panama City?

    The cheapest flight price from Illinois to Panama City is $186. On average you can expect to pay $818. The most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), can usually be booked for $532.

  • Can I find deals for flights from Illinois to Panama City that include hotel bookings?

    Yes. In addition to deals on Illinois to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Panama City.

  • Can I find deals for business class flights from Illinois to Panama City?

    Yes. Cheapflights offers flight deals from Illinois to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Panama City?

    Currently, February is the cheapest month in which you can book a flight from Illinois to Panama City (average of $102). Flying from Illinois to Panama City in June is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Illinois to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Illinois to Panama City

Discover the top 4 airlines that operate flights from Illinois to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$264Average$302FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$450Average$617FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$573Average$713FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$601Average$721FlexibilityNo cancel feeOn-time71%

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