How popular is this Missouri to North Carolina flight route?

Flights from Missouri to North Carolina have been viewed 4 times in the past calendar month.

How long is the flight from Missouri to North Carolina?

Departing from Missouri to North Carolina will take you 1h 58m. Missouri and North Carolina are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in North Carolina ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit North Carolina when rainfall is around 2.9 in.

If weather is an important factor for your trip to North Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to North Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.

Can I find deals for business class flights from Missouri to North Carolina?

Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$57+ Flights from Missouri to North Carolina

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheap flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Wed 12/2411:33 amMCI - RDU

1 stop11h 40mFrontier

Fri 12/266:00 amRDU - MCI

1 stop5h 08mFrontier

Deal found 12/3

$164

Wed 12/177:43 pmSTL - CLT

1 stop14h 39mFrontier

Sun 12/219:33 pmCLT - STL

1 stop13h 12mFrontier

Deal found 12/2

$172

Wed 12/314:27 pmSTL - RDU

1 stop15h 01mFrontier

Sun 1/49:05 pmRDU - STL

1 stop12h 07mFrontier

Deal found 12/3

$173

Wed 12/107:43 pmSTL - CLT

1 stop20h 06mFrontier

Wed 12/1710:45 amCLT - STL

1 stop12h 48mFrontier

Deal found 12/3

$174

Mon 12/159:54 amSTL - CLT

1 stop9h 31mFrontier

Tue 12/1610:45 amCLT - STL

1 stop12h 48mFrontier

Deal found 12/3

$180

Fri 12/199:07 amSTL - RDU

1 stop5h 29mFrontier

Sun 1/49:05 pmRDU - STL

1 stop12h 07mFrontier

Deal found 12/4

$188

Tue 12/93:30 pmSTL - CLT

1 stop17h 20mFrontier

Thu 12/1110:33 pmCLT - STL

1 stop11h 26mFrontier

Deal found 12/2

$192

Tue 12/163:30 pmSTL - CLT

1 stop17h 20mFrontier

Fri 12/192:51 pmCLT - STL

1 stop5h 51mFrontier

Deal found 12/2

$197

Fri 12/123:30 pmSTL - RDU

1 stop24h 14mFrontier

Tue 12/168:14 pmRDU - STL

1 stop27h 19mFrontier

Deal found 12/4

$199

Sat 12/137:43 pmSTL - TYS

1 stop16h 28mMultiple Airlines

Thu 12/1812:50 pmTYS - STL

1 stop10h 43mMultiple Airlines

Deal found 12/3

$206

Fri 12/1212:13 pmMCI - RDU

1 stop10h 59mFrontier

Mon 12/156:10 amRDU - MCI

1 stop6h 41mFrontier

Deal found 12/2

$208

Sat 12/137:43 pmSTL - TYS

1 stop16h 28mMultiple Airlines

Mon 12/151:05 pmTYS - STL

1 stop10h 28mMultiple Airlines

Deal found 12/2

$209

Best flights from Missouri to North Carolina
Discover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

Sat 1/248:13 amSTL - CLT

Nonstop1h 58mAmerican Airlines

Sat 1/3110:23 pmCLT - STL

Nonstop2h 03mAmerican Airlines

Deal found 12/3

$123

Fri 1/93:43 pmSTL - RDU

1 stop7h 29mFrontier

Sun 1/1110:11 pmRDU - STL

1 stop10h 54mFrontier

Deal found 12/4

$153

Sun 2/18:41 pmMCI - CLT

1 stop18h 37mMultiple Airlines

Wed 2/47:43 pmCLT - MCI

1 stop15h 48mMultiple Airlines

Deal found 12/4

$173

Sat 1/2410:19 amSTL - CLT

1 stop4h 46mDelta

Sat 1/315:00 pmCLT - STL

1 stop4h 43mDelta

Deal found 12/3

$177

Wed 1/712:55 pmMCI - RDU

2 stops6h 45mSouthwest

Mon 1/1211:20 amRDU - MCI

1 stop7h 10mSouthwest

Deal found 12/2

$191

Fri 1/95:04 pmMCI - CLT

1 stop22h 50mSpirit Airlines

Tue 1/136:01 pmCLT - MCI

1 stop23h 08mSpirit Airlines

Deal found 12/3

$204

Mon 1/126:30 amSTL - RDU

2 stops6h 36mUnited Airlines

Wed 1/146:25 amRDU - STL

2 stops7h 04mUnited Airlines

Deal found 12/4

$268

Wed 1/286:00 amSTL - TYS

1 stop5h 46mAmerican Airlines

Wed 2/411:19 amTYS - STL

1 stop7h 04mAmerican Airlines

Deal found 12/3

$159

Wed 12/2411:33 amMCI - RDU

1 stop11h 40mFrontier

Fri 12/266:00 amRDU - MCI

1 stop5h 08mFrontier

Deal found 12/3

$164

Thu 1/158:33 pmMCI - CLT

1 stop21h 09mMultiple Airlines

Wed 1/217:43 pmCLT - MCI

1 stop15h 48mMultiple Airlines

Deal found 12/4

$188

Mon 2/22:30 pmSTL - CLT

Nonstop1h 45mSouthwest

Thu 2/55:05 pmCLT - STL

Nonstop2h 10mSouthwest

Deal found 12/2

$194

Fri 1/237:59 pmMCI - RDU

Nonstop2h 25mDelta

Sun 2/17:05 amRDU - MCI

Nonstop3h 09mDelta

Deal found 12/3

$199

Thu 1/83:43 pmSTL - RDU

2 stops15h 57mFrontier

Mon 1/121:40 pmRDU - STL

1 stop9h 53mFrontier

Deal found 12/2

$189

Mon 1/2611:26 amMCI - MYR

1 stop6h 54mSpirit Airlines

Thu 1/298:15 pmMYR - MCI

1 stop15h 16mSpirit Airlines

Deal found 12/1

$210

Sun 2/87:59 pmMCI - RDU

Nonstop2h 25mDelta

Fri 2/207:10 amRDU - MCI

Nonstop3h 07mDelta

Deal found 12/3

$199

Fri 1/2311:55 amSTL - TYS

1 stop4h 47mAmerican Airlines

Mon 1/266:00 amTYS - STL

1 stop6h 05mAmerican Airlines

Deal found 12/3

$199

Sat 1/171:45 pmSTL - CLT

1 stop4h 30mSouthwest

Mon 1/195:05 pmCLT - STL

Nonstop2h 10mSouthwest

Deal found 12/2

$203

Sat 12/137:43 pmSTL - TYS

1 stop16h 28mMultiple Airlines

Mon 12/151:05 pmTYS - STL

1 stop10h 28mMultiple Airlines

Deal found 12/2

$209

Fri 2/67:59 pmMCI - RDU

Nonstop2h 25mDelta

Mon 2/97:05 amRDU - MCI

Nonstop3h 09mDelta

Deal found 12/1

$199

Sat 2/215:11 pmSTL - CLT

1 stop13h 46mFrontier

Sun 2/227:51 pmCLT - STL

1 stop27h 42mFrontier

Deal found 12/1

$206

Tue 3/311:08 amMCI - MYR

2 stops8h 38mAmerican Airlines

Wed 3/410:44 amMYR - MCI

1 stop6h 31mAmerican Airlines

Deal found 12/2

$208

Wed 12/103:30 pmSTL - CLT

1 stop27h 30mMultiple Airlines

Wed 12/1710:45 amCLT - STL

2 stops23h 55mMultiple Airlines

Deal found 12/3

$213

Thu 1/155:04 pmMCI - CLT

1 stop16h 13mSpirit Airlines

Wed 1/216:01 pmCLT - MCI

3 stops17h 30mSpirit Airlines

Deal found 12/4

$240

Wed 1/147:59 pmMCI - RDU

Nonstop2h 25mDelta

Sun 3/17:10 amRDU - MCI

Nonstop3h 07mDelta

Deal found 12/2

$199

Sun 1/256:30 amSTL - TYS

1 stop5h 54mUnited Airlines

Thu 1/296:45 amTYS - STL

1 stop6h 44mUnited Airlines

Deal found 12/2

$269

Sat 1/2410:25 amSTL - CLT

2 stops7h 50mSouthwest

Sat 1/311:05 pmCLT - STL

2 stops8h 50mSouthwest

Deal found 12/3

$224

Sun 12/143:30 pmSTL - CLT

1 stop5h 08mFrontier

Fri 12/192:51 pmCLT - STL

1 stop5h 51mFrontier

Deal found 12/3

$212

Thu 1/86:00 amSTL - MYR

1 stop7h 55mAmerican Airlines

Tue 1/1312:05 pmMYR - STL

1 stop3h 59mAmerican Airlines

Deal found 12/3

$214

Sun 2/111:26 amMCI - CLT

1 stop6h 22mSpirit Airlines

Wed 2/46:01 pmCLT - MCI

3 stops17h 30mSpirit Airlines

Deal found 12/4

$240

Mon 1/268:05 amMCI - RDU

1 stop6h 35mUnited Airlines

Thu 1/295:18 pmRDU - MCI

1 stop5h 41mUnited Airlines

Deal found 12/2

$271

Last-minute flights from Missouri to North Carolina
Discover last-minute flight deals from Missouri to North Carolina. Data last updated December 4, 2025 and is based on user searches.

Wed 12/2411:33 amMCI - RDU

1 stop11h 40mFrontier

Fri 12/266:00 amRDU - MCI

1 stop5h 08mFrontier

Deal found 12/3

$164

Wed 1/76:23 amMCI - RDU

1 stop5h 43mAmerican Airlines

Mon 1/124:35 pmRDU - MCI

1 stop7h 04mAmerican Airlines

Deal found 12/2

$163

Thu 1/83:43 pmSTL - RDU

1 stop7h 29mFrontier

Mon 1/128:14 pmRDU - STL

1 stop27h 20mFrontier

Deal found 12/4

$156

Fri 1/93:43 pmSTL - RDU

1 stop7h 29mFrontier

Sun 1/1110:11 pmRDU - STL

1 stop10h 54mFrontier

Deal found 12/3

$153

Mon 1/125:11 pmSTL - RDU

1 stop19h 47mFrontier

Wed 1/142:53 pmRDU - STL

1 stop8h 41mFrontier

Deal found 12/4

$158

Sat 1/173:43 pmSTL - CLT

1 stop25h 15mFrontier

Mon 1/269:56 pmCLT - STL

1 stop26h 37mFrontier

Deal found 12/4

$151

Sat 1/248:13 amSTL - CLT

Nonstop1h 58mAmerican Airlines

Sat 1/3110:23 pmCLT - STL

Nonstop2h 03mAmerican Airlines

Deal found 12/3

$123

Sat 1/245:42 pmSTL - CLT

1 stop14h 48mFrontier

Sun 1/255:13 pmCLT - STL

1 stop20h 37mFrontier

Deal found 12/3

$137

Wed 1/285:42 pmSTL - RDU

1 stop20h 58mFrontier

Sun 2/19:56 pmRDU - STL

1 stop26h 37mFrontier

Deal found 12/4

$143

Wed 1/286:00 amSTL - TYS

1 stop5h 46mAmerican Airlines

Wed 2/411:19 amTYS - STL

1 stop7h 04mAmerican Airlines

Deal found 12/3

$159

Sat 1/313:46 pmSTL - CLT

1 stop23h 32mFrontier

Wed 2/411:35 amCLT - STL

1 stop12h 58mFrontier

Deal found 12/3

$145

Sat 1/313:46 pmSTL - CLT

1 stop23h 32mMultiple Airlines

Sat 2/76:01 pmCLT - STL

1 stop6h 32mMultiple Airlines

Deal found 12/3

$163

One-way flights from Missouri to North Carolina
Search for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated December 4, 2025.

Mon 2/25:42 pmSTL - RDU

1 stop19h 17mFrontier

Deal found 12/2

$57

Tue 2/35:42 pmSTL - ORF

1 stop23h 43mMultiple Airlines

Deal found 12/2

$63

Sat 1/3111:00 amSTL - RDU

1 stop6h 06mFrontier

Deal found 12/2

$64

Fri 2/611:18 amSTL - CLT

1 stop5h 49mFrontier

Deal found 12/4

$64

Tue 2/36:50 amMCI - RDU

1 stop8h 00mSouthwest

Deal found 12/4

$68

Sun 2/18:41 pmMCI - CLT

1 stop18h 37mFrontier

Deal found 12/3

$68

Mon 3/25:11 pmSTL - ORF

1 stop18h 04mFrontier

Deal found 12/2

$69

Sat 1/313:46 pmSTL - CLT

1 stop23h 32mFrontier

Deal found 12/1

$69

Fri 2/611:18 amSTL - RDU

1 stop8h 33mFrontier

Deal found 12/4

$70

Fri 2/612:45 pmMCI - RDU

1 stop10h 26mFrontier

Deal found 12/2

$70

Fri 2/278:45 amSTL - CLT

1 stop11h 21mFrontier

Deal found 12/3

$70

Tue 2/39:00 amSTL - CLT

1 stop7h 20mSouthwest

Deal found 12/4

$72

Find flight deals from Missouri to North Carolina

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$123 (American Airlines)
One-way from	$57 (Kiwi.com)
Popular in	August
Cheapest in	October
Average price	$374
Good round-trip deal	$269 or less
Good one-way deal	$203 or less

Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.

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From Missouri to North Carolina

Search Deals

One-way flight from Missouri to North Carolina

Search Deals

Highest demand for flights based on searches. 11% potential increase in price ($52 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Missouri to North Carolina.

Search Deals

Price to beat on a one-way flight from Missouri to North Carolina.

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Sat 1/24

8:13 am-11:11 am

Nonstop1h 58m

Charlotte Douglas

Sat 1/31

10:23 pm-11:26 pm

Nonstop2h 03m

$123

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 1/9

3:43 pm-12:12 am

1 stop7h 29m

Raleigh-Durham

Sun 1/11

10:11 pm-8:05 am

1 stop10h 54m

$153

St. LouisKnoxville

STL - TYS

STLTYS

Lambert-St Louis

Wed 1/28

6:00 am-12:46 pm

1 stop5h 46m

Knoxville McGhee Tyson

Wed 2/4

11:19 am-5:23 pm

1 stop7h 04m

$159

Kansas CityRaleigh

MCI - RDU

MCIRDU

Kansas City

Wed 12/24

11:33 am-12:13 am

1 stop11h 40m

Raleigh-Durham

Fri 12/26

6:00 am-10:08 am

1 stop5h 08m

$164

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

Sun 2/1

8:41 pm-4:18 pm

1 stop18h 37m

Charlotte Douglas

Wed 2/4

7:43 pm-10:31 am

1 stop15h 48m

$173

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Sat 1/24

10:19 am-4:05 pm

1 stop4h 46m

Charlotte Douglas

Sat 1/31

5:00 pm-8:43 pm

1 stop4h 43m

$177

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

Thu 1/15

8:33 pm-6:42 pm

1 stop21h 09m

Charlotte Douglas

Wed 1/21

7:43 pm-10:31 am

1 stop15h 48m

$188

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 1/8

3:43 pm-8:40 am

2 stops15h 57m

Raleigh-Durham

Mon 1/12

1:40 pm-10:33 pm

1 stop9h 53m

$189

Kansas CityRaleigh

MCI - RDU

MCIRDU

Kansas City

Wed 1/7

12:55 pm-8:40 pm

2 stops6h 45m

Raleigh-Durham

Mon 1/12

11:20 am-5:30 pm

1 stop7h 10m

$191

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Mon 2/2

2:30 pm-5:15 pm

Nonstop1h 45m

Charlotte Douglas

Thu 2/5

5:05 pm-6:15 pm

Nonstop2h 10m

$194

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in December is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NC?

It’s optimal to fly from Missouri to North Carolina in the evening. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Missouri to North Carolina?

Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing North Carolina

See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,250 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,011 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,066 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,047 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,091 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Missouri to North Carolina flight route?
Flights from Missouri to North Carolina have been viewed 4 times in the past calendar month.
How long is the flight from Missouri to North Carolina?
Departing from Missouri to North Carolina will take you 1h 58m. Missouri and North Carolina are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Missouri to North Carolina that include hotel bookings?
Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to North Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.
Can I find deals for business class flights from Missouri to North Carolina?
Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to North Carolina?
Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in December is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to North Carolina

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$128	Average$222	FlexibilityNo cancel fee	On-time62%
Spirit Airlines	Cheapest$139	Average$222	FlexibilityNo cancel fee	On-time65%
Southwest	Cheapest$150	Average$368	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$157	Average$351	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$170	Average$378	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$263	Average$393	FlexibilityNo cancel fee	On-time69%

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$57+ Cheap flights from Missouri to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North CarolinaExplore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Find flight deals from Missouri to North Carolina

Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated December 4, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

What is the cheapest time of day to fly from MO to NC?

Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

What is the cheapest day to fly from Missouri to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on December 16, 2024.

Reviews of airlines servicing North Carolina

See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Missouri to North Carolina flight route?

How long is the flight from Missouri to North Carolina?

Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

How can I find direct flights from Missouri to North Carolina?

Can I find deals for business class flights from Missouri to North Carolina?

What is the cheapest month to book a flight from Missouri to North Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Missouri to North Carolina

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Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.