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North Carolina

$60+ Cheap flights from Missouri to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Missouri to North Carolina

Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$128
(Frontier)

One-way from

$60
(Priceline)

Popular in

August

Cheapest in

October

Average price

$374

Good round-trip deal

$317 or less

Good one-way deal

$209 or less
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
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From Missouri to North Carolina
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One-way flight from Missouri to North Carolina
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Highest demand for flights based on searches. 11% potential increase in price ($51 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from Missouri to North Carolina.
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Price to beat on a one-way flight from Missouri to North Carolina.
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Find flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Frontier deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3111:00 amSTL - RDU
1 stop6h 06mFrontier
Wed 2/42:15 pmRDU - STL
1 stop10h 18mFrontier
Deal found 1/7$128
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:42 pmSTL - CLT
1 stop15h 58mFrontier
Tue 2/102:46 pmCLT - STL
1 stop8h 41mFrontier
Deal found 1/6$131
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/173:49 pmSTL - CLT
1 stop17h 28mMultiple Airlines
Tue 2/2411:12 amCLT - STL
1 stop12h 15mMultiple Airlines
Deal found 1/6$132
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:42 pmSTL - CLT
1 stop15h 58mFrontier
Fri 1/305:13 pmCLT - STL
1 stop22h 33mFrontier
Deal found 1/7$135
This Kiwi.com deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/18:41 pmMCI - CLT
1 stop18h 37mFrontier
Sun 2/85:13 pmCLT - MCI
1 stop27h 38mFrontier
Deal found 1/8$135
This Frontier deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3111:00 amSTL - RDU
1 stop6h 06mFrontier
Mon 2/23:44 pmRDU - STL
1 stop8h 49mFrontier
Deal found 1/7$136
This Expedia deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:42 pmSTL - CLT
1 stop15h 58mFrontier
Sat 2/79:59 pmCLT - STL
1 stop11h 05mFrontier
Deal found 1/7$136
This Frontier deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/149:41 amSTL - RDU
1 stop9h 49mFrontier
Sat 2/213:35 pmRDU - STL
1 stop9h 24mFrontier
Deal found 1/6$144
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/118:17 pmSTL - RDU
1 stop20h 43mFrontier
Sat 2/143:35 pmRDU - STL
1 stop9h 24mFrontier
Deal found 1/6$148
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:49 pmSTL - RDU
1 stop24h 10mFrontier
Tue 3/101:48 pmRDU - STL
1 stop10h 31mFrontier
Deal found 1/7$149
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/15:42 pmSTL - RDU
1 stop21h 15mFrontier
Wed 2/42:15 pmRDU - STL
1 stop10h 18mFrontier
Deal found 1/7$152
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:42 pmSTL - CLT
1 stop15h 13mFrontier
Sun 2/19:59 pmCLT - STL
1 stop12h 22mFrontier
Deal found 1/7$152

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Fly from

Missouri

Fly to

North Carolina

Route

Depart

Return

Price

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 2/17

3:49 pm-10:17 am

1 stop17h 28m

Charlotte Douglas

Sat 2/28

5:49 pm-11:59 pm

1 stop7h 10m

$132

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 2/3

5:42 pm-4:54 pm

1 stop22h 12m

Charlotte Douglas

Tue 2/10

6:01 pm-10:27 pm

1 stop29h 26m

$132

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 2/6

8:22 pm-11:56 pm

1 stop26h 34m

Raleigh-Durham

Tue 2/10

2:53 pm-10:27 pm

1 stop8h 34m

$152

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 3/1

3:49 pm-8:37 am

1 stop15h 48m

Raleigh-Durham

Fri 3/6

4:31 pm-11:19 pm

1 stop7h 48m

$159

St. LouisNorfolk

STL - ORF

STLORF

Lambert-St Louis

Wed 1/28

5:42 pm-3:06 pm

1 stop20h 24m

Norfolk

Mon 2/2

7:33 pm-11:33 pm

2 stops29h 00m

$159

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 2/14

9:41 am-8:30 pm

1 stop9h 49m

Raleigh-Durham

Thu 2/19

4:04 pm-11:59 pm

1 stop8h 55m

$160

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 2/18

8:20 am-4:20 pm

1 stop7h 00m

Charlotte Douglas

Wed 2/25

8:25 am-9:35 am

Nonstop2h 10m

$171

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 1/27

5:42 pm-10:40 am

1 stop15h 58m

Charlotte Douglas

Fri 1/30

9:06 am-11:33 pm

2 stops15h 27m

$171

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 2/3

10:19 am-4:05 pm

1 stop4h 46m

Charlotte Douglas

Tue 2/10

5:50 pm-8:37 pm

1 stop3h 47m

$181

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

Tue 1/27

5:04 pm-10:40 am

1 stop16h 36m

Charlotte Douglas

Fri 2/6

7:43 pm-10:31 am

1 stop15h 48m

$186

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in July is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NC?

Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 8, 2026.

It’s optimal to fly from Missouri to North Carolina in the afternoon. By choosing this option you can save up to 24% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Missouri to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on January 3, 2026.

Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated January 8, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,250 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,250 reviews
Southwest
8.0
Very good
4,250 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,025 reviews
Southwest
8.0
Very good
4,250 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,139 reviews
Southwest
8.0
Very good
4,250 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,095 reviews
Southwest
8.0
Very good
4,250 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,062 reviews
Southwest
8.0
Very good
4,250 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to North Carolina flight route?

    Flights from Missouri to North Carolina have been viewed 5 times in the past calendar month.

  • How long is the flight from Missouri to North Carolina?

    Departing from Missouri to North Carolina will take you 4h 46m. Missouri and North Carolina are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

    Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.

  • Can I find deals for business class flights from Missouri to North Carolina?

    Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to North Carolina?

    Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in July is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to North Carolina

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Top 6 airlines flying from Missouri to North Carolina

Discover the top 6 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$132Average$227FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$222FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$150Average$368FlexibilityNo cancel feeOn-time63%
DeltaCheapest$157Average$348FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$186Average$374FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$381FlexibilityNo cancel feeOn-time69%

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