$64+ Cheap flights from Missouri to North Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Mar 8 — Mar 151
1 adult, Economy
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Find cheap flights from Missouri to North Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to North Carolina
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Cheapest flights from Missouri to North CarolinaExplore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Wed 2/259:25 pm
RDU
- STL
1 stop27h 34m
Frontier
Deal found 2/3![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Tue 2/246:25 am
RDU
- STL
1 stop25h 26m
Frontier
Deal found 2/3![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Sun 3/14:30 pm
RDU
- STL
1 stop15h 21m
Frontier
Deal found 2/3![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Fri 2/276:54 pm
RDU
- STL
1 stop12h 57m
Frontier
Deal found 2/3![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Wed 3/116:50 am
RDU
- STL
1 stop4h 47m
Frontier
Deal found 2/4![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Thu 2/266:55 pm
RDU
- STL
1 stop12h 56m
Frontier
Deal found 2/3![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Thu 2/266:55 pm
RDU
- STL
1 stop12h 56m
Frontier
Deal found 2/3![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- CLT
1 stop21h 02m
Frontier
Tue 3/107:48 pm
CLT
- STL
1 stop28h 31m
Frontier
Deal found 2/3![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- CLT
2 stops26h 34m
Multiple Airlines
Wed 2/252:46 pm
CLT
- STL
1 stop8h 41m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- RDU
1 stop16h 11m
Multiple Airlines
Thu 3/56:55 pm
RDU
- STL
1 stop17h 54m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:49 pm
STL
- RDU
1 stop21h 09m
Frontier
Wed 3/42:53 pm
RDU
- STL
1 stop8h 34m
Frontier
Deal found 2/5![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- RDU
2 stops19h 49m
Multiple Airlines
Wed 2/252:53 pm
RDU
- STL
1 stop8h 34m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$155
Best flights from Missouri to North CarolinaDiscover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 6, 2026.
Discover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 6, 2026.
This Expedia deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:45 am
MCI
- RDU
1 stop11h 01m
Frontier
Wed 3/256:50 am
RDU
- MCI
1 stop5h 08m
Frontier
Deal found 2/5![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 am
MCI
- MYR
2 stops10h 48m
Spirit Airlines
Tue 4/76:28 pm
MYR
- MCI
1 stop18h 01m
Spirit Airlines
Deal found 2/3![Spirit Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:40 pm
MCI
- ORF
2 stops12h 00m
Multiple Airlines
Thu 3/128:41 pm
ORF
- MCI
1 stop15h 48m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$193
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:45 am
STL
- RDU
1 stop3h 57m
Delta
Sun 7/265:45 am
RDU
- STL
1 stop4h 45m
Delta
Deal found 2/3![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:21 am
STL
- CLT
Nonstop1h 58m
American Airlines
Sat 8/2211:10 am
CLT
- STL
Nonstop2h 01m
American Airlines
Deal found 2/5![American Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:25 am
STL
- TYS
2 stops8h 15m
Southwest
Sat 4/181:55 pm
TYS
- STL
1 stop7h 05m
Southwest
Deal found 2/2![Southwest logo]()
$239
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:45 am
STL
- AVL
1 stop4h 42m
United Airlines
Wed 4/225:48 pm
AVL
- STL
1 stop6h 08m
United Airlines
Deal found 2/5![United Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- TYS
1 stop25h 37m
Multiple Airlines
Tue 3/1010:00 am
TYS
- STL
1 stop14h 19m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$196
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:50 pm
STL
- RDU
1 stop4h 28m
Delta
Sun 4/265:38 am
RDU
- STL
1 stop5h 04m
Delta
Deal found 2/3![Delta logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:33 pm
MCI
- RDU
2 stops26h 37m
Frontier
Thu 2/266:55 pm
RDU
- MCI
1 stop16h 01m
Frontier
Deal found 2/3![Frontier logo]()
$197
This CheapOair deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/44:24 pm
MCI
- CLT
1 stop23h 30m
Spirit Airlines
Wed 3/111:24 pm
CLT
- MCI
1 stop23h 05m
Spirit Airlines
Deal found 2/5![Spirit Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
STL
- RDU
1 stop5h 51m
Delta
Sun 7/56:35 am
RDU
- STL
1 stop5h 10m
Delta
Deal found 2/4![Delta logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:21 am
STL
- RDU
1 stop11h 54m
Frontier
Tue 5/55:52 pm
RDU
- STL
2 stops13h 58m
Frontier
Deal found 2/5![Frontier logo]()
$198
This CheapOair deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/73:40 pm
MCI
- CLT
1 stop16h 26m
Multiple Airlines
Sat 3/146:00 am
CLT
- MCI
1 stop6h 29m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
STL
- RDU
1 stop4h 39m
Delta
Sun 3/225:38 am
RDU
- STL
1 stop5h 08m
Delta
Deal found 2/3![Delta logo]()
$197
This CheapOair deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:26 am
MCI
- MYR
1 stop19h 47m
Spirit Airlines
Tue 3/39:09 am
MYR
- MCI
2 stops31h 20m
Spirit Airlines
Deal found 2/5![Spirit Airlines logo]()
$217
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:12 pm
STL
- RDU
1 stop20h 36m
Frontier
Thu 4/306:00 am
RDU
- STL
1 stop5h 30m
Frontier
Deal found 2/3![Frontier logo]()
$200
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:05 am
STL
- AVL
1 stop5h 23m
American Airlines
Sun 3/15:11 am
AVL
- STL
1 stop4h 24m
American Airlines
Deal found 2/5![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:15 am
STL
- TYS
1 stop6h 55m
Southwest
Sun 4/127:35 pm
TYS
- STL
1 stop5h 10m
Southwest
Deal found 2/3![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
STL
- RDU
1 stop6h 33m
Delta
Thu 4/305:38 am
RDU
- STL
1 stop5h 04m
Delta
Deal found 2/4![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:57 pm
STL
- AVL
1 stop3h 55m
American Airlines
Sun 3/15:11 am
AVL
- STL
1 stop4h 24m
American Airlines
Deal found 2/3![American Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:47 am
STL
- CLT
1 stop8h 07m
Multiple Airlines
Sun 3/157:38 pm
CLT
- STL
1 stop12h 24m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:26 am
MCI
- ORF
1 stop30h 00m
Spirit Airlines
Thu 3/128:41 pm
ORF
- MCI
1 stop15h 48m
Spirit Airlines
Deal found 2/3![Spirit Airlines logo]()
$232
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/153:49 pm
STL
- CLT
1 stop14h 00m
Frontier
Wed 2/188:43 am
CLT
- STL
1 stop14h 44m
Frontier
Deal found 2/3![Frontier logo]()
$216
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:10 am
MCI
- CLT
2 stops5h 30m
Southwest
Wed 2/2511:05 am
CLT
- MCI
1 stop4h 15m
Southwest
Deal found 2/5![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:15 am
STL
- RDU
1 stop6h 53m
Delta
Fri 5/225:20 am
RDU
- STL
1 stop3h 58m
Delta
Deal found 2/3![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:05 am
STL
- AVL
1 stop5h 23m
American Airlines
Sat 2/284:34 pm
AVL
- STL
1 stop5h 38m
American Airlines
Deal found 2/4![American Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:57 pm
STL
- RDU
1 stop4h 35m
Delta
Sat 4/114:17 pm
RDU
- STL
1 stop5h 49m
Delta
Deal found 2/4![Delta logo]()
$197
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:45 am
MCI
- MYR
2 stops10h 48m
Spirit Airlines
Tue 3/246:28 pm
MYR
- MCI
2 stops30h 25m
Spirit Airlines
Deal found 2/3![Spirit Airlines logo]()
$241
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2912:20 pm
MCI
- CLT
1 stop6h 45m
Southwest
Sat 4/43:50 pm
CLT
- MCI
1 stop8h 10m
Southwest
Deal found 2/5![Southwest logo]()
$269
Last-minute flights from Missouri to North CarolinaDiscover last-minute flight deals from Missouri to North Carolina. Data last updated February 6, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to North Carolina. Data last updated February 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Wed 2/259:25 pm
RDU
- STL
1 stop27h 34m
Frontier
Deal found 2/3![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Tue 2/246:25 am
RDU
- STL
1 stop25h 26m
Frontier
Deal found 2/3![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Sun 3/14:30 pm
RDU
- STL
1 stop15h 21m
Frontier
Deal found 2/3![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:17 pm
STL
- RDU
1 stop20h 38m
Frontier
Thu 2/266:55 pm
RDU
- STL
1 stop12h 56m
Frontier
Deal found 2/3![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Fri 2/276:54 pm
RDU
- STL
1 stop12h 57m
Frontier
Deal found 2/3![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Thu 2/266:55 pm
RDU
- STL
1 stop12h 56m
Frontier
Deal found 2/3![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- CLT
2 stops26h 34m
Multiple Airlines
Wed 2/252:46 pm
CLT
- STL
1 stop8h 41m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- RDU
2 stops19h 49m
Multiple Airlines
Wed 2/252:53 pm
RDU
- STL
1 stop8h 34m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:49 pm
STL
- RDU
1 stop21h 09m
Frontier
Wed 3/42:53 pm
RDU
- STL
1 stop8h 34m
Frontier
Deal found 2/5![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- CLT
1 stop21h 02m
Frontier
Tue 3/107:48 pm
CLT
- STL
1 stop28h 31m
Frontier
Deal found 2/3![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- RDU
1 stop16h 11m
Multiple Airlines
Thu 3/56:55 pm
RDU
- STL
1 stop17h 54m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Wed 3/116:50 am
RDU
- STL
1 stop4h 47m
Frontier
Deal found 2/4![Frontier logo]()
$138
One-way flights from Missouri to North CarolinaSearch for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated February 6, 2026.
Search for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated February 6, 2026.
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:36 pm
STL
- RDU
1 stop6h 54m
Frontier
Deal found 2/2![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:49 pm
STL
- RDU
1 stop27h 41m
Frontier
Deal found 2/2![Frontier logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- CLT
1 stop21h 02m
Frontier
Deal found 2/3![Frontier logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:49 pm
STL
- CLT
1 stop24h 05m
Multiple Airlines
Deal found 2/5![Multiple Airlines logo]()
$68
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:00 am
MCI
- RDU
1 stop20h 00m
Frontier
Deal found 2/2![Frontier logo]()
$70
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
- RDU
1 stop12h 15m
Frontier
Deal found 2/2![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- RDU
1 stop10h 02m
Frontier
Deal found 2/5![Frontier logo]()
$72
This Trip.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:55 am
MCI
- RDU
1 stop12h 15m
Frontier
Deal found 2/3![Frontier logo]()
$73
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:26 am
MCI
- CLT
1 stop11h 30m
Spirit Airlines
Deal found 2/3![Spirit Airlines logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Deal found 2/3![Frontier logo]()
$74
This WAYA deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:00 am
MCI
- RDU
1 stop6h 09m
Frontier
Deal found 2/5![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- RDU
1 stop26h 50m
Frontier
Deal found 2/5![Frontier logo]()
$79
Find flight deals from Missouri to North Carolina
Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated February 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $131 (Kiwi.com) |
One-way from | $64 (Frontier) |
Popular in | August |
Cheapest in | October |
Average price | $382 |
Good round-trip deal | $219 or less |
Good one-way deal | $187 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.
Fly from
Missouri
Fly to
North Carolina
Route
Depart
Return
Price
Kansas CityRaleigh
MCI - RDU
MCIRDU
Kansas City
Wed 3/18
11:45 am-11:46 pm
1 stop11h 01m
Raleigh-Durham
Wed 3/25
6:50 am-10:58 am
1 stop5h 08m
$160
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Wed 4/1
5:45 am-5:33 pm
2 stops10h 48m
Myrtle Beach Intl
Tue 4/7
6:28 pm-11:29 am
1 stop18h 01m
$193
Kansas CityNorfolk
MCI - ORF
MCIORF
Kansas City
Sat 3/7
8:40 pm-9:40 am
2 stops12h 00m
Norfolk
Thu 3/12
8:41 pm-11:29 am
1 stop15h 48m
$193
St. LouisKnoxville
STL - TYS
STLTYS
Lambert-St Louis
Tue 3/3
3:49 pm-6:26 pm
1 stop25h 37m
Knoxville McGhee Tyson
Tue 3/10
10:00 am-11:19 pm
1 stop14h 19m
$196
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Thu 7/23
6:45 am-11:42 am
1 stop3h 57m
Raleigh-Durham
Sun 7/26
5:45 am-9:30 am
1 stop4h 45m
$197
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Thu 4/23
6:50 pm-12:18 am
1 stop4h 28m
Raleigh-Durham
Sun 4/26
5:38 am-9:42 am
1 stop5h 04m
$197
Kansas CityRaleigh
MCI - RDU
MCIRDU
Kansas City
Mon 2/23
8:33 pm-12:10 am
2 stops26h 37m
Raleigh-Durham
Thu 2/26
6:55 pm-9:56 am
1 stop16h 01m
$197
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Wed 7/1
6:00 am-12:51 pm
1 stop5h 51m
Raleigh-Durham
Sun 7/5
6:35 am-10:45 am
1 stop5h 10m
$197
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Thu 3/19
6:00 am-11:39 am
1 stop4h 39m
Raleigh-Durham
Sun 3/22
5:38 am-9:46 am
1 stop5h 08m
$197
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Mon 3/30
6:00 am-1:33 pm
1 stop6h 33m
Raleigh-Durham
Thu 4/30
5:38 am-9:42 am
1 stop5h 04m
$197
Showing 1-10 of 60 results
Best time to book a flight from Missouri to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
MCI-RDU
MCI-MYR
MCI-ORF
STL-RDU
STL-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to North Carolina
USMO-USNC
MCI-RDU
MCI-MYR
MCI-ORF
STL-RDU
What is the cheapest month to book a flight from Missouri to North Carolina?
Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in July is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to NC?
Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 6, 2026.
It’s optimal to fly from Missouri to North Carolina in the afternoon. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Missouri to North Carolina?
Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated February 6, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to North Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to North Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to North Carolina by cabin class
Find flights from Missouri to North Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and North Carolina flights
Browse other Missouri and North Carolina flight options. Last updated on February 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from North Carolina
Find the right flight back to Missouri after your stay in North Carolina
Missouri to North Carolina flights
Consider these flights traveling from Missouri to North Carolina.
Top 5 airlines flying from Missouri to North Carolina
Discover the top 5 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$132 | Average$224 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$132 | Average$343 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$150 | Average$363 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$186 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$253 | Average$361 | FlexibilityNo cancel fee | On-time69% |