How popular is this Missouri to North Carolina flight route?

Flights from Missouri to North Carolina have been viewed 4 times in the past calendar month.

How long is the flight from Missouri to North Carolina?

Departing from Missouri to North Carolina will take you 2h 31m. Missouri and North Carolina are separated by a distance of 902 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in North Carolina ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit North Carolina when rainfall is around 2.9 in.

If weather is an important factor for your trip to North Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to North Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.

Can I find deals for business class flights from Missouri to North Carolina?

Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$64+ Flights from Missouri to North Carolina

Q: How much does it cost to fly round-trip from Missouri to North Carolina?

Airfare is below average for this route at the moment. Missouri to North Carolina flights typically cost between $304 and $412 in January. The cheapest round-trip price found within the last 3 days was $128 on Frontier (Jan 24-Jan 27).

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Find cheap flights from Missouri to North Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Wed 12/3111:33 amMCI - RDU

1 stop11h 40mFrontier

Mon 1/56:00 amRDU - MCI

1 stop5h 08mFrontier

Deal found 12/22

$162

Wed 12/3111:33 amMCI - RDU

1 stop11h 40mFrontier

Fri 1/26:00 amRDU - MCI

1 stop5h 08mFrontier

Deal found 12/22

$187

Wed 12/2411:33 amMCI - RDU

1 stop11h 40mFrontier

Wed 12/316:00 amRDU - MCI

1 stop5h 08mFrontier

Deal found 12/21

$213

Wed 12/242:04 pmSTL - CLT

Nonstop1h 56mAmerican Airlines

Sat 12/2710:56 pmCLT - STL

Nonstop2h 00mAmerican Airlines

Deal found 12/22

$252

Wed 12/311:50 pmSTL - CLT

1 stop6h 00mSouthwest

Sat 1/39:15 pmCLT - STL

1 stop4h 00mSouthwest

Deal found 12/21

$261

Wed 12/246:00 amSTL - CLT

1 stop3h 53mDelta

Sat 12/276:00 amCLT - STL

1 stop3h 58mDelta

Deal found 12/22

$272

Wed 12/247:05 amSTL - CLT

Nonstop2h 02mAmerican Airlines

Mon 12/2910:55 pmCLT - STL

Nonstop2h 00mAmerican Airlines

Deal found 12/21

$276

Thu 12/253:10 pmSTL - CLT

1 stop5h 10mUnited Airlines

Sat 12/276:00 amCLT - STL

2 stops9h 26mUnited Airlines

Deal found 12/22

$277

Mon 12/2910:40 amSTL - RDU

1 stop5h 17mFrontier

Wed 12/3111:48 amRDU - STL

1 stop11h 45mFrontier

Deal found 12/21

$282

Wed 12/242:04 pmSTL - CLT

Nonstop1h 56mAmerican Airlines

Sun 12/286:00 pmCLT - STL

1 stop6h 44mAmerican Airlines

Deal found 12/20

$286

Tue 12/307:05 amSTL - CLT

Nonstop2h 02mAmerican Airlines

Sat 1/310:56 pmCLT - STL

Nonstop2h 00mAmerican Airlines

Deal found 12/20

$287

Wed 12/241:22 pmSTL - CLT

1 stop5h 57mDelta

Sun 12/288:15 amCLT - STL

1 stop5h 06mDelta

Deal found 12/21

$296

Best flights from Missouri to North Carolina
Discover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

Tue 1/65:11 pmSTL - RDU

1 stop22h 41mFrontier

Tue 1/272:54 pmRDU - STL

1 stop9h 39mFrontier

Deal found 12/23

$133

Fri 1/235:42 pmSTL - ORF

1 stop25h 33mMultiple Airlines

Mon 1/266:45 amORF - STL

1 stop17h 48mMultiple Airlines

Deal found 12/23

$149

Sat 4/257:59 pmMCI - RDU

Nonstop2h 31mDelta

Tue 4/287:00 amRDU - MCI

Nonstop2h 55mDelta

Deal found 12/22

$199

Sat 1/171:45 pmSTL - CLT

1 stop4h 30mSouthwest

Sun 1/188:25 amCLT - STL

Nonstop2h 10mSouthwest

Deal found 12/22

$209

Sat 1/178:13 amSTL - CLT

Nonstop1h 58mAmerican Airlines

Sun 1/188:25 amCLT - STL

Nonstop2h 15mAmerican Airlines

Deal found 12/22

$217

Tue 4/2812:12 pmMCI - MYR

1 stop20h 30mSpirit Airlines

Wed 5/67:51 pmMYR - MCI

1 stop16h 16mSpirit Airlines

Deal found 12/21

$230

Sun 1/115:11 pmSTL - RDU

1 stop20h 37mFrontier

Fri 1/163:22 pmRDU - STL

1 stop16h 29mFrontier

Deal found 12/21

$141

Wed 2/183:49 pmSTL - CLT

1 stop15h 24mMultiple Airlines

Fri 2/206:01 pmCLT - STL

1 stop7h 26mMultiple Airlines

Deal found 12/21

$150

Wed 1/148:32 pmSTL - RDU

1 stop10h 55mFrontier

Thu 1/152:48 pmRDU - STL

1 stop8h 46mFrontier

Deal found 12/21

$141

Wed 2/48:22 pmSTL - RDU

2 stops16h 51mMultiple Airlines

Mon 2/99:56 pmRDU - STL

1 stop25h 31mMultiple Airlines

Deal found 12/21

$154

Wed 2/411:17 amCOU - CLT

1 stop5h 07mUnited Airlines

Sat 2/710:44 amCLT - COU

1 stop7h 35mUnited Airlines

Deal found 12/22

$372

Wed 4/227:59 pmMCI - RDU

Nonstop2h 31mDelta

Wed 4/297:00 amRDU - MCI

Nonstop2h 55mDelta

Deal found 12/20

$199

Sat 1/173:43 pmSTL - CLT

1 stop25h 15mFrontier

Tue 1/2011:35 amCLT - STL

2 stops20h 16mFrontier

Deal found 12/22

$167

Sat 1/105:11 pmSTL - RDU

1 stop14h 49mMultiple Airlines

Thu 1/152:48 pmRDU - STL

1 stop8h 46mMultiple Airlines

Deal found 12/21

$168

Wed 1/217:59 pmMCI - RDU

Nonstop2h 25mDelta

Wed 1/287:05 amRDU - MCI

Nonstop3h 09mDelta

Deal found 12/22

$199

Wed 2/183:49 pmSTL - CLT

1 stop15h 24mFrontier

Sun 2/225:13 pmCLT - STL

1 stop20h 56mFrontier

Deal found 12/22

$170

Sat 1/171:45 pmSTL - CLT

1 stop4h 30mSouthwest

Tue 1/208:25 amCLT - STL

Nonstop2h 10mSouthwest

Deal found 12/22

$227

Thu 1/223:54 pmSTL - CLT

Nonstop1h 50mAmerican Airlines

Sat 1/241:59 pmCLT - STL

Nonstop2h 05mAmerican Airlines

Deal found 12/22

$240

Wed 1/217:59 pmMCI - RDU

Nonstop2h 25mDelta

Sat 1/247:05 amRDU - MCI

Nonstop3h 09mDelta

Deal found 12/21

$199

Sat 1/105:11 pmSTL - RDU

1 stop14h 49mMultiple Airlines

Sat 1/173:18 pmRDU - STL

1 stop8h 16mMultiple Airlines

Deal found 12/21

$181

Sat 5/236:00 amMCI - MYR

1 stop4h 48mSpirit Airlines

Sat 5/3012:50 pmMYR - MCI

1 stop12h 09mSpirit Airlines

Deal found 12/20

$249

Mon 1/1911:26 amMCI - CLT

1 stop22h 29mMultiple Airlines

Mon 1/267:50 pmCLT - MCI

1 stop21h 19mMultiple Airlines

Deal found 12/22

$181

Sat 3/710:35 amSTL - CLT

1 stop4h 20mSouthwest

Sun 3/158:45 pmCLT - STL

1 stop4h 30mSouthwest

Deal found 12/20

$241

Wed 4/17:59 pmMCI - RDU

Nonstop2h 25mDelta

Fri 5/297:58 pmRDU - MCI

1 stop4h 57mDelta

Deal found 12/21

$209

Wed 1/215:04 pmMCI - MYR

1 stop18h 08mSpirit Airlines

Wed 1/2810:00 amMYR - MCI

2 stops25h 31mSpirit Airlines

Deal found 12/22

$253

Sat 5/166:38 pmMCI - CLT

Nonstop2h 17mAmerican Airlines

Sat 5/231:00 pmCLT - MCI

Nonstop2h 21mAmerican Airlines

Deal found 12/22

$263

Mon 1/510:40 amSTL - RDU

1 stop27h 45mFrontier

Wed 1/78:14 pmRDU - STL

1 stop27h 19mFrontier

Deal found 12/23

$206

Tue 1/207:00 amMCI - CLT

3 stops26h 55mSpirit Airlines

Thu 1/227:43 pmCLT - MCI

1 stop15h 48mSpirit Airlines

Deal found 12/20

$255

Thu 1/85:11 pmSTL - CLT

1 stop14h 51mMultiple Airlines

Mon 1/126:01 pmCLT - STL

1 stop29h 33mMultiple Airlines

Deal found 12/21

$192

Sat 1/176:00 amMCI - AVL

1 stop6h 48mAmerican Airlines

Mon 1/196:43 pmAVL - MCI

1 stop5h 52mAmerican Airlines

Deal found 12/21

$269

Last-minute flights from Missouri to North Carolina
Discover last-minute flight deals from Missouri to North Carolina. Data last updated December 23, 2025 and is based on user searches.

Sun 1/115:11 pmSTL - RDU

1 stop20h 37mFrontier

Fri 1/163:22 pmRDU - STL

1 stop16h 29mFrontier

Deal found 12/21

$140

Sun 1/115:11 pmSTL - RDU

1 stop20h 37mFrontier

Tue 1/135:00 pmRDU - STL

1 stop6h 34mFrontier

Deal found 12/21

$141

Sun 1/115:11 pmSTL - RDU

1 stop20h 37mFrontier

Thu 1/152:48 pmRDU - STL

1 stop8h 46mFrontier

Deal found 12/21

$153

Mon 1/128:50 amSTL - RDU

1 stop28h 08mFrontier

Wed 1/142:53 pmRDU - STL

1 stop8h 41mFrontier

Deal found 12/21

$130

Mon 1/125:11 pmSTL - RDU

1 stop19h 47mFrontier

Fri 1/163:22 pmRDU - STL

1 stop16h 29mFrontier

Deal found 12/21

$132

Tue 1/135:11 pmSTL - RDU

1 stop16h 49mMultiple Airlines

Wed 1/142:53 pmRDU - STL

1 stop8h 41mMultiple Airlines

Deal found 12/21

$150

Mon 1/195:11 pmSTL - CLT

1 stop22h 43mMultiple Airlines

Mon 1/269:56 pmCLT - STL

1 stop26h 37mMultiple Airlines

Deal found 12/22

$142

Tue 1/205:42 pmSTL - RDU

1 stop16h 18mMultiple Airlines

Tue 1/272:54 pmRDU - STL

1 stop9h 39mMultiple Airlines

Deal found 12/21

$149

Thu 1/225:42 pmSTL - CLT

1 stop14h 48mFrontier

Sun 1/259:59 pmCLT - STL

1 stop12h 22mFrontier

Deal found 12/22

$151

Fri 1/235:42 pmSTL - ORF

1 stop25h 33mMultiple Airlines

Mon 1/266:45 amORF - STL

1 stop17h 48mMultiple Airlines

Deal found 12/23

$149

Sat 1/2411:00 amSTL - RDU

1 stop6h 06mFrontier

Tue 1/272:54 pmRDU - STL

1 stop9h 39mFrontier

Deal found 12/21

$128

Tue 1/275:42 pmSTL - RDU

1 stop21h 48mFrontier

Thu 1/295:12 pmRDU - STL

1 stop7h 21mFrontier

Deal found 12/22

$142

One-way flights from Missouri to North Carolina
Search for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated December 23, 2025.

Sat 1/2412:12 pmSTL - ORF

1 stop7h 03mFrontier

Deal found 12/23

$64

Sat 1/2411:00 amSTL - RDU

1 stop6h 06mFrontier

Deal found 12/22

$64

Sat 1/178:32 pmSTL - RDU

1 stop10h 55mFrontier

Deal found 12/22

$67

Wed 1/215:42 pmSTL - ORF

1 stop20h 24mFrontier

Deal found 12/23

$68

Wed 1/215:42 pmSTL - RDU

1 stop20h 58mFrontier

Deal found 12/22

$68

Tue 1/205:42 pmSTL - CLT

1 stop22h 12mMultiple Airlines

Deal found 12/21

$68

Sat 2/2110:00 amMCI - RDU

1 stop20h 00mFrontier

Deal found 12/21

$70

Thu 1/83:43 pmSTL - RDU

1 stop7h 29mFrontier

Deal found 12/22

$74

Sat 1/173:43 pmSTL - CLT

1 stop25h 15mFrontier

Deal found 12/21

$74

Sat 2/218:36 pmMCI - CLT

1 stop18h 42mFrontier

Deal found 12/22

$75

Tue 1/205:42 pmSTL - ORF

1 stop23h 43mMultiple Airlines

Deal found 12/23

$76

Fri 2/206:13 pmMCI - RDU

1 stop21h 03mFrontier

Deal found 12/22

$77

Find flight deals from Missouri to North Carolina

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$128 (Priceline)
One-way from	$64 (Frontier)
Popular in	August
Cheapest in	October
Average price	$374
Good round-trip deal	$325 or less
Good one-way deal	$188 or less

Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.

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From Missouri to North Carolina

Search Deals

One-way flight from Missouri to North Carolina

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($47 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Missouri to North Carolina.

Search Deals

Price to beat on a one-way flight from Missouri to North Carolina.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Tue 1/6

5:11 pm-4:52 pm

1 stop22h 41m

Raleigh-Durham

Tue 1/27

2:54 pm-11:33 pm

1 stop9h 39m

$133

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 1/11

5:11 pm-2:48 pm

1 stop20h 37m

Raleigh-Durham

Fri 1/16

3:22 pm-6:51 am

1 stop16h 29m

$141

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 1/14

8:32 pm-8:27 am

1 stop10h 55m

Raleigh-Durham

Thu 1/15

2:48 pm-10:34 pm

1 stop8h 46m

$141

St. LouisNorfolk

STL - ORF

STLORF

Lambert-St Louis

Fri 1/23

5:42 pm-8:15 pm

1 stop25h 33m

Norfolk

Mon 1/26

6:45 am-11:33 pm

1 stop17h 48m

$149

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 2/18

3:49 pm-8:13 am

1 stop15h 24m

Charlotte Douglas

Fri 2/20

6:01 pm-12:27 am

1 stop7h 26m

$150

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 2/4

8:22 pm-2:13 pm

2 stops16h 51m

Raleigh-Durham

Mon 2/9

9:56 pm-10:27 pm

1 stop25h 31m

$154

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Sat 1/17

3:43 pm-5:58 pm

1 stop25h 15m

Charlotte Douglas

Tue 1/20

11:35 am-6:51 am

2 stops20h 16m

$167

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 1/10

5:11 pm-9:00 am

1 stop14h 49m

Raleigh-Durham

Thu 1/15

2:48 pm-10:34 pm

1 stop8h 46m

$168

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 2/18

3:49 pm-8:13 am

1 stop15h 24m

Charlotte Douglas

Sun 2/22

5:13 pm-1:09 pm

1 stop20h 56m

$170

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sat 1/10

5:11 pm-9:00 am

1 stop14h 49m

Raleigh-Durham

Sat 1/17

3:18 pm-10:34 pm

1 stop8h 16m

$181

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in July is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NC?

It’s optimal to fly from Missouri to North Carolina in the evening. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Missouri to North Carolina?

Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Missouri to North Carolina?

Reviews of airlines servicing North Carolina

See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,253 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,014 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,105 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,075 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Missouri to North Carolina flight route?
Flights from Missouri to North Carolina have been viewed 4 times in the past calendar month.
How long is the flight from Missouri to North Carolina?
Departing from Missouri to North Carolina will take you 2h 31m. Missouri and North Carolina are separated by a distance of 902 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Missouri to North Carolina that include hotel bookings?
Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to North Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.
Can I find deals for business class flights from Missouri to North Carolina?
Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to North Carolina?
Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in July is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Missouri to North Carolina

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$128	Average$227	FlexibilityNo cancel fee	On-time62%
Spirit Airlines	Cheapest$139	Average$222	FlexibilityNo cancel fee	On-time65%
Southwest	Cheapest$150	Average$369	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$157	Average$347	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$178	Average$376	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$263	Average$393	FlexibilityNo cancel fee	On-time69%

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$64+ Cheap flights from Missouri to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to North Carolina with Cheapflights

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Cheap flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North CarolinaExplore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Find flight deals from Missouri to North Carolina

Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated December 23, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

What is the cheapest time of day to fly from MO to NC?

Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

What is the cheapest day to fly from Missouri to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on December 16, 2024.

How much does it cost to fly round-trip from Missouri to North Carolina?

Reviews of airlines servicing North Carolina

See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Missouri to North Carolina flight route?

How long is the flight from Missouri to North Carolina?

Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

How can I find direct flights from Missouri to North Carolina?

Can I find deals for business class flights from Missouri to North Carolina?

What is the cheapest month to book a flight from Missouri to North Carolina?

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Alternative routes for Missouri to North Carolina

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Top 6 airlines flying from Missouri to North Carolina

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Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.