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$51+ Cheap flights from Missouri to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Find flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:04 pmSTL - RDU
1 stop11h 08mFrontier
Mon 12/86:10 amRDU - STL
1 stop4h 42mFrontier
Deal found 11/4$110
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:30 pmSTL - CLT
1 stop5h 08mFrontier
Mon 12/1510:32 amCLT - STL
1 stop13h 01mFrontier
Deal found 11/3$120
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:42 amSTL - RDU
1 stop12h 31mFrontier
Tue 1/610:46 amRDU - STL
1 stop12h 47mFrontier
Deal found 11/5$123
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:13 pmMCI - RDU
1 stop10h 59mFrontier
Mon 12/156:10 amRDU - MCI
1 stop6h 41mFrontier
Deal found 11/4$124
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:30 pmSTL - CLT
1 stop5h 08mFrontier
Mon 12/89:20 pmCLT - STL
1 stop26h 13mFrontier
Deal found 11/4$125
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/203:14 pmSTL - RDU
1 stop7h 18mFrontier
Sun 11/233:02 pmRDU - STL
1 stop9h 55mFrontier
Deal found 11/4$127
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:30 pmSTL - RDU
1 stop15h 53mFrontier
Tue 12/98:14 pmRDU - STL
1 stop27h 19mFrontier
Deal found 11/4$133
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:13 pmSTL - RDU
1 stop23h 31mFrontier
Sat 12/68:14 pmRDU - STL
1 stop13h 45mFrontier
Deal found 11/4$135
This Booking.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:54 amSTL - CLT
1 stop10h 44mFrontier
Sat 12/68:52 amCLT - STL
1 stop14h 41mFrontier
Deal found 11/3$135
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:30 pmSTL - RDU
1 stop18h 01mFrontier
Thu 12/116:26 pmRDU - STL
1 stop16h 48mFrontier
Deal found 11/4$139
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:48 amSTL - RDU
1 stop24h 12mFrontier
Sat 12/2711:40 amRDU - STL
1 stop23h 00mFrontier
Deal found 11/4$142
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:30 pmSTL - CLT
1 stop5h 08mFrontier
Sun 1/118:46 pmCLT - STL
1 stop12h 04mFrontier
Deal found 11/4$142

Cheap flight deals from Missouri to North Carolina

Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$110
(Frontier)

One-way from

$51
(Trip.com)

Popular in

August

Cheapest in

September

Average price

$363

Good round-trip deal

$329 or less

Good one-way deal

$164 or less
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
Search Deals
From Missouri to North Carolina
Search Deals
One-way flight from Missouri to North Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Missouri to North Carolina.
Search Deals
Price to beat on a one-way flight from Missouri to North Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Fly from

Missouri

Fly to

North Carolina

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 12/7

9:54 am-8:23 am

1 stop21h 29m

Raleigh-Durham

Tue 12/9

8:14 pm-10:33 pm

1 stop27h 19m

$133

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Mon 12/1

4:13 pm-4:44 pm

1 stop23h 31m

Raleigh-Durham

Sat 12/6

8:14 pm-8:59 am

1 stop13h 45m

$135

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 1/28

5:11 pm-7:57 am

1 stop13h 46m

Charlotte Douglas

Fri 1/30

10:01 pm-10:33 pm

1 stop25h 32m

$135

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Mon 12/1

7:03 pm-1:35 pm

2 stops17h 32m

Raleigh-Durham

Thu 12/4

6:00 am-11:07 am

1 stop6h 07m

$182

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Sun 11/16

2:12 pm-8:43 am

1 stop17h 31m

Raleigh-Durham

Tue 11/18

8:00 am-10:05 am

1 stop27h 05m

$195

Kansas CityRaleigh

MCI - RDU

MCIRDU

Kansas City

Tue 3/3

7:59 pm-11:24 pm

Nonstop2h 25m

Raleigh-Durham

Wed 3/11

7:55 am-9:41 am

Nonstop2h 46m

$199

Kansas CityRaleigh

MCI - RDU

MCIRDU

Kansas City

Sat 4/25

6:55 pm-10:22 pm

Nonstop2h 27m

Raleigh-Durham

Tue 4/28

7:55 am-9:44 am

Nonstop2h 49m

$199

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Sat 12/13

11:19 am-6:28 pm

1 stop6h 09m

Charlotte Douglas

Sun 12/14

6:33 am-10:45 am

1 stop5h 12m

$201

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Fri 4/24

1:30 pm-7:21 pm

1 stop4h 51m

Charlotte Douglas

Mon 4/27

7:59 pm-11:38 pm

1 stop4h 39m

$201

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Sat 12/6

10:45 am-4:13 pm

1 stop4h 28m

Charlotte Douglas

Sat 12/13

2:12 pm-6:00 pm

1 stop4h 48m

$201

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in December is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NC?

Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

It’s optimal to fly from Missouri to North Carolina in the evening. By choosing this option you can save up to 35% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Missouri to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Missouri to North Carolina?

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated November 5, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,004 reviews
Southwest
8.0
Very good
4,240 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,002 reviews
Southwest
8.0
Very good
4,240 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,042 reviews
Southwest
8.0
Very good
4,240 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,116 reviews
Southwest
8.0
Very good
4,240 reviews

Food

7.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to North Carolina flight route?

    Flights from Missouri to North Carolina have been viewed 4 times in the past calendar month.

  • How long is the flight from Missouri to North Carolina?

    Departing from Missouri to North Carolina will take you 1h 45m. Missouri and North Carolina are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to North Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $67. Users have also found prices from $91 and $99 on Southwest and Spirit Airlines, respectively.

  • Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

    Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.

  • Can I find deals for business class flights from Missouri to North Carolina?

    Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to North Carolina?

    Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in December is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to North Carolina

Discover the top 6 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$128Average$219FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$225FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$150Average$372FlexibilityNo cancel feeOn-time63%
DeltaCheapest$157Average$341FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$170Average$386FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$264Average$399FlexibilityNo cancel feeOn-time69%

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