$66+ Cheap flights from Missouri to North Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Mar 23 — Mar 301
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to North Carolina with Cheapflights
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to North Carolina
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Cheapest flights from Missouri to North CarolinaExplore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:21 am
STL
- RDU
1 stop26h 41m
Frontier
Tue 4/144:00 pm
RDU
- STL
1 stop15h 50m
Frontier
Deal found 2/21![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- RDU
1 stop10h 55m
Frontier
Mon 3/304:06 pm
RDU
- STL
1 stop19h 26m
Frontier
Deal found 2/21![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- RDU
1 stop10h 55m
Frontier
Wed 3/254:12 pm
RDU
- STL
1 stop19h 19m
Frontier
Deal found 2/20![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Tue 4/216:00 am
RDU
- STL
1 stop25h 50m
Frontier
Deal found 2/20![Frontier logo]()
$156
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Fri 4/173:11 pm
RDU
- STL
1 stop9h 08m
Frontier
Deal found 2/20![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:53 am
MCI
- RDU
1 stop11h 22m
Frontier
Mon 4/206:10 am
RDU
- MCI
1 stop5h 18m
Frontier
Deal found 2/20![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
- CLT
1 stop6h 34m
Frontier
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Deal found 2/19![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:59 pm
STL
- RDU
1 stop23h 17m
Frontier
Sun 5/39:49 pm
RDU
- STL
1 stop22h 43m
Frontier
Deal found 2/20![Frontier logo]()
$171
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:12 pm
STL
- CLT
1 stop19h 40m
Frontier
Sun 5/107:49 pm
CLT
- STL
1 stop24h 23m
Frontier
Deal found 2/20![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:32 am
STL
- RDU
1 stop19h 55m
Frontier
Mon 3/3010:38 pm
RDU
- STL
2 stops12h 54m
Frontier
Deal found 2/19![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Wed 3/116:50 am
RDU
- STL
1 stop4h 47m
Frontier
Deal found 2/21![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Sun 3/154:07 pm
RDU
- STL
1 stop22h 27m
Frontier
Deal found 2/19![Frontier logo]()
$180
Best flights from Missouri to North CarolinaDiscover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 21, 2026.
Discover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 21, 2026.
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Sun 4/199:49 pm
RDU
- STL
1 stop22h 43m
Frontier
Deal found 2/19![Frontier logo]()
$171
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:25 am
STL
- RDU
1 stop6h 17m
United Airlines
Sat 3/141:27 pm
RDU
- STL
1 stop5h 33m
United Airlines
Deal found 2/20![United Airlines logo]()
$205
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:57 pm
STL
- MYR
1 stop3h 58m
American Airlines
Thu 3/195:10 am
MYR
- STL
1 stop4h 25m
American Airlines
Deal found 2/18![American Airlines logo]()
$205
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:50 am
STL
- GSO
1 stop4h 42m
Delta
Sat 4/45:46 pm
GSO
- STL
1 stop4h 20m
Delta
Deal found 2/19![Delta logo]()
$215
This CheapOair deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:51 pm
MCI
- CLT
1 stop27h 03m
Multiple Airlines
Sat 5/236:00 am
CLT
- MCI
1 stop6h 09m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$234
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:24 pm
MCI
- CLT
1 stop11h 14m
Spirit Airlines
Tue 3/2411:12 am
CLT
- MCI
2 stops25h 17m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:15 am
STL
- TYS
2 stops8h 50m
Southwest
Wed 3/252:25 pm
TYS
- STL
1 stop5h 20m
Southwest
Deal found 2/18![Southwest logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:32 am
STL
- RDU
1 stop19h 55m
Frontier
Mon 3/3010:38 pm
RDU
- STL
2 stops12h 54m
Frontier
Deal found 2/19![Frontier logo]()
$174
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:41 pm
STL
- GSO
1 stop4h 08m
Delta
Wed 4/2911:27 am
GSO
- STL
1 stop5h 57m
Delta
Deal found 2/20![Delta logo]()
$215
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:57 pm
STL
- MYR
1 stop3h 58m
American Airlines
Fri 3/275:10 am
MYR
- STL
1 stop4h 25m
American Airlines
Deal found 2/17![American Airlines logo]()
$217
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:51 pm
STL
- RDU
1 stop14h 46m
Frontier
Thu 4/3010:38 pm
RDU
- STL
1 stop25h 41m
Frontier
Deal found 2/19![Frontier logo]()
$200
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:40 am
STL
- CLT
1 stop7h 30m
Southwest
Mon 4/68:40 pm
CLT
- STL
1 stop4h 25m
Southwest
Deal found 2/21![Southwest logo]()
$241
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:06 am
STL
- MYR
1 stop4h 33m
American Airlines
Sat 3/76:00 am
MYR
- STL
2 stops7h 33m
American Airlines
Deal found 2/18![American Airlines logo]()
$221
This Expedia deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/283:49 pm
STL
- RDU
1 stop15h 48m
Frontier
Mon 3/24:04 pm
RDU
- STL
1 stop8h 55m
Frontier
Deal found 2/18![Frontier logo]()
$202
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:25 am
STL
- MYR
2 stops9h 24m
United Airlines
Sat 3/712:57 pm
MYR
- STL
2 stops9h 08m
United Airlines
Deal found 2/18![United Airlines logo]()
$246
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:15 am
MCI
- MYR
1 stop5h 35m
Spirit Airlines
Thu 5/712:50 pm
MYR
- MCI
1 stop12h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/44:24 pm
MCI
- RDU
1 stop14h 28m
Multiple Airlines
Sun 3/84:18 pm
RDU
- MCI
1 stop25h 05m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:41 pm
STL
- GSO
1 stop4h 30m
Delta
Mon 5/46:00 pm
GSO
- STL
1 stop6h 36m
Delta
Deal found 2/18![Delta logo]()
$242
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:15 am
MCI
- MYR
1 stop5h 35m
Spirit Airlines
Thu 5/712:50 pm
MYR
- MCI
1 stop12h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:45 am
STL
- MYR
1 stop5h 32m
United Airlines
Wed 4/83:15 pm
MYR
- STL
1 stop6h 53m
United Airlines
Deal found 2/18![United Airlines logo]()
$250
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:06 am
STL
- MYR
1 stop4h 33m
American Airlines
Wed 3/46:01 am
MYR
- STL
1 stop4h 39m
American Airlines
Deal found 2/17![American Airlines logo]()
$231
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:35 am
STL
- CLT
2 stops8h 10m
Southwest
Wed 5/207:20 pm
CLT
- STL
1 stop3h 40m
Southwest
Deal found 2/18![Southwest logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:16 pm
STL
- RDU
1 stop18h 09m
Frontier
Mon 3/234:07 pm
RDU
- STL
1 stop19h 25m
Frontier
Deal found 2/18![Frontier logo]()
$222
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:15 am
MCI
- MYR
1 stop5h 35m
Spirit Airlines
Sun 4/2612:50 pm
MYR
- MCI
1 stop12h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:50 pm
STL
- CLT
1 stop6h 57m
Delta
Wed 5/206:00 am
CLT
- STL
1 stop4h 26m
Delta
Deal found 2/18![Delta logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:08 pm
MCI
- CLT
2 stops14h 52m
Multiple Airlines
Fri 3/139:00 pm
CLT
- MCI
1 stop15h 29m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:45 am
STL
- CLT
2 stops7h 54m
United Airlines
Sat 4/115:35 pm
CLT
- STL
1 stop4h 33m
United Airlines
Deal found 2/18![United Airlines logo]()
$256
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:10 am
STL
- TYS
1 stop6h 30m
Southwest
Fri 3/273:45 pm
TYS
- STL
1 stop7h 25m
Southwest
Deal found 2/20![Southwest logo]()
$265
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:57 pm
STL
- MYR
1 stop3h 58m
American Airlines
Tue 3/316:01 am
MYR
- STL
2 stops7h 43m
American Airlines
Deal found 2/18![American Airlines logo]()
$247
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:54 pm
STL
- CLT
1 stop6h 42m
Frontier
Sun 4/57:49 pm
CLT
- STL
1 stop14h 59m
Frontier
Deal found 2/19![Frontier logo]()
$230
Last-minute flights from Missouri to North CarolinaDiscover last-minute flight deals from Missouri to North Carolina. Data last updated February 21, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to North Carolina. Data last updated February 21, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- CLT
1 stop21h 02m
Frontier
Tue 3/101:59 pm
CLT
- STL
1 stop10h 20m
Frontier
Deal found 2/18![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Wed 3/116:50 am
RDU
- STL
1 stop4h 47m
Frontier
Deal found 2/21![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- RDU
1 stop20h 43m
Frontier
Sun 3/154:07 pm
RDU
- STL
1 stop22h 27m
Frontier
Deal found 2/19![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:32 am
STL
- RDU
1 stop19h 55m
Frontier
Mon 3/3010:38 pm
RDU
- STL
2 stops12h 54m
Frontier
Deal found 2/19![Frontier logo]()
$174
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:51 pm
STL
- RDU
1 stop28h 02m
Frontier
Wed 3/186:50 am
RDU
- STL
1 stop4h 47m
Frontier
Deal found 2/20![Frontier logo]()
$189
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:45 am
MCI
- RDU
1 stop11h 01m
Frontier
Wed 3/256:50 am
RDU
- MCI
1 stop5h 08m
Frontier
Deal found 2/19![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:23 pm
MCI
- RDU
1 stop4h 48m
Frontier
Wed 3/256:50 am
RDU
- MCI
1 stop5h 08m
Frontier
Deal found 2/17![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- RDU
1 stop10h 55m
Frontier
Mon 3/304:06 pm
RDU
- STL
1 stop19h 26m
Frontier
Deal found 2/21![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- RDU
1 stop10h 55m
Frontier
Wed 3/254:12 pm
RDU
- STL
1 stop19h 19m
Frontier
Deal found 2/20![Frontier logo]()
$152
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:20 pm
MCI
- RDU
1 stop4h 51m
Frontier
Wed 3/256:50 am
RDU
- MCI
1 stop5h 08m
Frontier
Deal found 2/18![Frontier logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- ORF
2 stops30h 30m
Multiple Airlines
Mon 3/3011:33 am
ORF
- STL
1 stop23h 59m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$190
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:47 am
STL
- RDU
1 stop6h 49m
Frontier
Thu 4/306:00 am
RDU
- STL
1 stop5h 30m
Frontier
Deal found 2/18![Frontier logo]()
$195
One-way flights from Missouri to North CarolinaSearch for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.
Search for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.
This Trip.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:32 am
STL
- RDU
1 stop11h 14m
Frontier
Deal found 2/18![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- RDU
1 stop26h 52m
Frontier
Deal found 2/20![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- ORF
1 stop13h 09m
Frontier
Deal found 2/20![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- ORF
1 stop13h 09m
Frontier
Deal found 2/19![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:32 am
STL
- ORF
1 stop21h 43m
Frontier
Deal found 2/21![Frontier logo]()
$72
This Trip.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/92:09 pm
STL
- RDU
1 stop9h 02m
Frontier
Deal found 2/18![Frontier logo]()
$73
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:29 pm
STL
- RDU
1 stop4h 46m
Frontier
Deal found 2/20![Frontier logo]()
$80
This Orbitz deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:31 pm
MCI
- RDU
1 stop6h 44m
Frontier
Deal found 2/18![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 2/20![Frontier logo]()
$80
This Trip.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:45 am
MCI
- RDU
1 stop10h 15m
Frontier
Deal found 2/21![Frontier logo]()
$81
This Trip.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:45 am
MCI
- RDU
1 stop11h 01m
Frontier
Deal found 2/18![Frontier logo]()
$82
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 2/20![Frontier logo]()
$86
Find flight deals from Missouri to North Carolina
Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated February 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $131 (Kiwi.com) |
One-way from | $66 (Trip.com) |
Popular in | August |
Cheapest in | October |
Average price | $350 |
Good round-trip deal | $338 or less |
Good one-way deal | $149 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.
Fly from
Missouri
Fly to
North Carolina
Route
Depart
Return
Price
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Fri 4/17
4:59 pm-4:56 pm
1 stop22h 57m
Raleigh-Durham
Sun 4/19
9:49 pm-7:32 pm
1 stop22h 43m
$171
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Wed 3/11
11:32 am-8:27 am
1 stop19h 55m
Raleigh-Durham
Mon 3/30
10:38 pm-10:32 am
2 stops12h 54m
$174
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Mon 3/30
4:51 pm-8:37 am
1 stop14h 46m
Raleigh-Durham
Thu 4/30
10:38 pm-11:19 pm
1 stop25h 41m
$200
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Sat 2/28
3:49 pm-8:37 am
1 stop15h 48m
Raleigh-Durham
Mon 3/2
4:04 pm-11:59 pm
1 stop8h 55m
$202
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Sat 3/7
6:25 am-1:42 pm
1 stop6h 17m
Raleigh-Durham
Sat 3/14
1:27 pm-6:00 pm
1 stop5h 33m
$205
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Mon 3/16
6:57 pm-11:55 pm
1 stop3h 58m
Myrtle Beach Intl
Thu 3/19
5:10 am-8:35 am
1 stop4h 25m
$205
St. LouisGreensboro
STL - GSO
STLGSO
Lambert-St Louis
Wed 4/1
10:50 am-4:32 pm
1 stop4h 42m
Greensboro/H. Point
Sat 4/4
5:46 pm-9:06 pm
1 stop4h 20m
$215
St. LouisGreensboro
STL - GSO
STLGSO
Lambert-St Louis
Wed 4/22
4:41 pm-9:49 pm
1 stop4h 08m
Greensboro/H. Point
Wed 4/29
11:27 am-4:24 pm
1 stop5h 57m
$215
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Mon 3/23
6:57 pm-11:55 pm
1 stop3h 58m
Myrtle Beach Intl
Fri 3/27
5:10 am-8:35 am
1 stop4h 25m
$217
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Wed 3/4
6:06 am-11:39 am
1 stop4h 33m
Myrtle Beach Intl
Sat 3/7
6:00 am-12:33 pm
2 stops7h 33m
$221
Showing 1-10 of 60 results
Best time to book a flight from Missouri to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
STL-RDU
MCI-RDU
STL-CLT
MCI-CLT
STL-ORF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to North Carolina
USMO-USNC
STL-RDU
MCI-RDU
STL-CLT
MCI-CLT
What is the cheapest month to book a flight from Missouri to North Carolina?
Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in February is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to NC?
Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 21, 2026.
It’s optimal to fly from Missouri to North Carolina in the afternoon. By choosing this option you can save up to 31% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Missouri to North Carolina?
Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on February 17, 2026.
Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated February 21, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to North Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to North Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to North Carolina by cabin class
Find flights from Missouri to North Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and North Carolina flights
Browse other Missouri and North Carolina flight options. Last updated on February 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from North Carolina
Find the right flight back to Missouri after your stay in North Carolina
Missouri to North Carolina flights
Consider these flights traveling from Missouri to North Carolina.
Top 5 airlines flying from Missouri to North Carolina
Discover the top 5 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$340 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$132 | Average$222 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$150 | Average$366 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$186 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$358 | FlexibilityNo cancel fee | On-time69% |