$63+ Cheap flights from Missouri to North Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to North Carolina with Cheapflights
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Cheapest flights from Missouri to North CarolinaExplore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- RDU
1 stop12h 23m
Frontier
Tue 5/1212:54 pm
RDU
- STL
1 stop21h 01m
Frontier
Deal found 3/18![Frontier logo]()
$134
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:19 am
MCI
- RDU
1 stop10h 36m
Frontier
Sun 4/196:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Deal found 3/20![Frontier logo]()
$140
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
- CLT
1 stop6h 34m
Frontier
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Deal found 3/20![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:55 pm
STL
- RDU
1 stop12h 09m
Frontier
Tue 5/1212:54 pm
RDU
- STL
1 stop21h 01m
Frontier
Deal found 3/18![Frontier logo]()
$146
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:59 pm
STL
- RDU
1 stop16h 00m
Frontier
Wed 4/156:55 pm
RDU
- STL
1 stop25h 26m
Frontier
Deal found 3/22![Frontier logo]()
$151
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:19 pm
STL
- CLT
1 stop21h 35m
Frontier
Wed 4/157:49 pm
CLT
- STL
1 stop24h 32m
Frontier
Deal found 3/20![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:23 pm
STL
- RDU
1 stop12h 07m
Frontier
Thu 5/712:54 pm
RDU
- STL
1 stop5h 00m
Frontier
Deal found 3/21![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:53 am
MCI
- RDU
1 stop10h 27m
Frontier
Mon 5/46:10 am
RDU
- MCI
1 stop5h 18m
Frontier
Deal found 3/19![Frontier logo]()
$155
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- RDU
1 stop16h 59m
Frontier
Mon 4/2710:51 pm
RDU
- STL
1 stop25h 28m
Frontier
Deal found 3/21![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:53 am
MCI
- RDU
1 stop10h 02m
Frontier
Mon 4/206:10 am
RDU
- MCI
1 stop5h 18m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/54:59 pm
STL
- CLT
1 stop6h 37m
Frontier
Thu 4/94:18 pm
CLT
- STL
1 stop8h 07m
Frontier
Deal found 3/19![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Sat 5/912:26 pm
RDU
- STL
1 stop7h 57m
Frontier
Deal found 3/20![Frontier logo]()
$161
Best flights from Missouri to North CarolinaDiscover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:00 am
STL
- ILM
1 stop6h 28m
Delta
Wed 8/510:20 am
ILM
- STL
1 stop6h 38m
Delta
Deal found 3/17![Delta logo]()
$241
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:40 pm
STL
- CLT
1 stop4h 20m
Southwest
Mon 6/84:40 pm
CLT
- STL
Nonstop2h 10m
Southwest
Deal found 3/19![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
STL
- CLT
1 stop6h 50m
United Airlines
Sun 8/236:00 am
CLT
- STL
1 stop4h 49m
United Airlines
Deal found 3/21![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:12 pm
SGF
- CLT
Nonstop2h 20m
American Airlines
Sat 6/139:23 am
CLT
- SGF
Nonstop2h 34m
American Airlines
Deal found 3/21![American Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:25 am
STL
- RDU
Nonstop1h 50m
Southwest
Tue 4/146:10 am
RDU
- STL
Nonstop2h 10m
Southwest
Deal found 3/19![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:59 pm
MCI
- RDU
Nonstop2h 31m
Delta
Tue 4/217:00 am
RDU
- MCI
Nonstop2h 56m
Delta
Deal found 3/17![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:30 am
STL
- ILM
1 stop6h 58m
United Airlines
Tue 8/254:09 pm
ILM
- STL
1 stop6h 13m
United Airlines
Deal found 3/18![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Sun 8/231:35 pm
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 3/21![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:38 pm
MCI
- RDU
1 stop4h 38m
Delta
Wed 6/37:23 am
RDU
- MCI
Nonstop2h 52m
Delta
Deal found 3/19![Delta logo]()
$327
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:45 pm
MCI
- CLT
1 stop5h 14m
United Airlines
Wed 6/176:15 am
CLT
- MCI
1 stop5h 14m
United Airlines
Deal found 3/18![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:00 pm
STL
- CLT
1 stop4h 40m
Southwest
Sun 5/38:50 pm
CLT
- STL
1 stop3h 55m
Southwest
Deal found 3/21![Southwest logo]()
$323
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:34 am
MCI
- CLT
1 stop6h 39m
Delta
Sat 5/306:59 am
CLT
- MCI
1 stop5h 17m
Delta
Deal found 3/19![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:45 am
STL
- CLT
2 stops10h 04m
United Airlines
Sat 4/1811:09 am
CLT
- STL
2 stops11h 04m
United Airlines
Deal found 3/19![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:45 pm
STL
- RDU
Nonstop1h 50m
Southwest
Mon 5/116:10 pm
RDU
- STL
1 stop6h 30m
Southwest
Deal found 3/17![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:59 pm
MCI
- RDU
Nonstop2h 29m
Delta
Wed 6/37:23 am
RDU
- MCI
Nonstop2h 52m
Delta
Deal found 3/17![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:41 pm
STL
- CLT
1 stop6h 04m
United Airlines
Tue 6/910:27 am
CLT
- STL
2 stops11h 49m
United Airlines
Deal found 3/18![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:10 pm
MCI
- CLT
2 stops5h 45m
Southwest
Wed 6/108:15 pm
CLT
- MCI
1 stop4h 10m
Southwest
Deal found 3/19![Southwest logo]()
$334
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:55 pm
MCI
- RDU
Nonstop2h 27m
Delta
Sun 9/67:55 am
RDU
- MCI
Nonstop2h 49m
Delta
Deal found 3/17![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:21 am
STL
- MYR
1 stop4h 56m
United Airlines
Sat 4/253:15 pm
MYR
- STL
1 stop6h 58m
United Airlines
Deal found 3/21![United Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:55 am
MCI
- CLT
2 stops8h 00m
Southwest
Sat 5/212:15 pm
CLT
- MCI
1 stop8h 00m
Southwest
Deal found 3/21![Southwest logo]()
$334
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:59 pm
MCI
- RDU
Nonstop2h 29m
Delta
Mon 6/87:55 am
RDU
- MCI
Nonstop2h 49m
Delta
Deal found 3/17![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:13 pm
STL
- CLT
1 stop7h 16m
United Airlines
Sat 8/2211:17 am
CLT
- STL
2 stops9h 14m
United Airlines
Deal found 3/17![United Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:10 pm
STL
- CLT
2 stops7h 40m
Southwest
Wed 4/156:40 am
CLT
- STL
2 stops7h 20m
Southwest
Deal found 3/19![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:12 pm
MCI
- ILM
1 stop5h 47m
Delta
Sat 5/96:00 am
ILM
- MCI
1 stop4h 29m
Delta
Deal found 3/17![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 am
STL
- RDU
1 stop4h 36m
United Airlines
Sat 4/46:00 am
RDU
- STL
2 stops7h 22m
United Airlines
Deal found 3/18![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:35 pm
MCI
- ORF
1 stop7h 15m
Southwest
Sat 5/91:15 pm
ORF
- MCI
1 stop7h 00m
Southwest
Deal found 3/19![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:30 am
MCI
- RDU
1 stop4h 38m
Delta
Sun 4/197:00 am
RDU
- MCI
Nonstop2h 56m
Delta
Deal found 3/18![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:45 am
STL
- MYR
1 stop5h 33m
United Airlines
Sat 5/2310:34 am
MYR
- STL
2 stops11h 44m
United Airlines
Deal found 3/21![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:40 pm
MCI
- RDU
Nonstop2h 20m
Southwest
Sat 6/208:20 pm
RDU
- MCI
1 stop4h 05m
Southwest
Deal found 3/17![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:17 pm
MCI
- RDU
1 stop4h 38m
Delta
Wed 4/297:00 am
RDU
- MCI
Nonstop2h 56m
Delta
Deal found 3/22![Delta logo]()
$349
Last-minute flights from Missouri to North CarolinaDiscover last-minute flight deals from Missouri to North Carolina. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to North Carolina. Data last updated March 22, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:54 pm
STL
- CLT
1 stop6h 42m
Frontier
Tue 4/74:33 pm
CLT
- STL
1 stop7h 52m
Frontier
Deal found 3/19![Frontier logo]()
$180
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/54:59 pm
STL
- CLT
1 stop6h 37m
Frontier
Thu 4/94:18 pm
CLT
- STL
1 stop8h 07m
Frontier
Deal found 3/19![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:19 pm
STL
- CLT
1 stop21h 35m
Frontier
Wed 4/157:49 pm
CLT
- STL
1 stop24h 32m
Frontier
Deal found 3/20![Frontier logo]()
$151
This Expedia deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:19 pm
STL
- RDU
1 stop20h 43m
Frontier
Tue 4/147:37 pm
RDU
- STL
1 stop28h 42m
Frontier
Deal found 3/19![Frontier logo]()
$180
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:59 pm
STL
- RDU
1 stop16h 00m
Frontier
Wed 4/156:55 pm
RDU
- STL
1 stop25h 26m
Frontier
Deal found 3/22![Frontier logo]()
$151
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:53 am
MCI
- RDU
1 stop10h 02m
Frontier
Mon 4/206:10 am
RDU
- MCI
1 stop5h 18m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:19 am
MCI
- RDU
1 stop10h 36m
Frontier
Sun 4/196:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Deal found 3/20![Frontier logo]()
$140
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
- CLT
1 stop6h 34m
Frontier
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Deal found 3/20![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Sun 4/2612:47 pm
RDU
- STL
1 stop11h 32m
Frontier
Deal found 3/22![Frontier logo]()
$181
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- RDU
1 stop16h 59m
Frontier
Mon 4/2710:51 pm
RDU
- STL
1 stop25h 28m
Frontier
Deal found 3/21![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:39 am
STL
- CLT
1 stop6h 34m
Frontier
Mon 4/278:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Deal found 3/20![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:53 am
MCI
- RDU
1 stop10h 27m
Frontier
Mon 5/46:10 am
RDU
- MCI
1 stop5h 18m
Frontier
Deal found 3/19![Frontier logo]()
$155
One-way flights from Missouri to North CarolinaSearch for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:24 pm
MCI
- RDU
1 stop12h 40m
Frontier
Deal found 3/21![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:33 pm
STL
- RDU
1 stop5h 00m
Frontier
Deal found 3/19![Frontier logo]()
$69
This Orbitz deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:31 pm
MCI
- RDU
1 stop5h 24m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
- RDU
1 stop8h 31m
Frontier
Deal found 3/21![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/18![Frontier logo]()
$74
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/22![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:19 am
MCI
- RDU
1 stop10h 36m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Trip.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:25 am
STL
- RDU
1 stop10h 30m
Frontier
Deal found 3/17![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
- RDU
1 stop11h 43m
Frontier
Deal found 3/18![Frontier logo]()
$78
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:34 pm
MCI
- RDU
1 stop19h 57m
Frontier
Deal found 3/20![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:23 pm
STL
- RDU
1 stop17h 41m
Frontier
Deal found 3/18![Frontier logo]()
$81
Find flight deals from Missouri to North Carolina
Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated March 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $134 (Kiwi.com) |
One-way from | $63 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $423 |
Good round-trip deal | $299 or less |
Good one-way deal | $185 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisWilmington
STL - ILM
STLILM
Lambert-St Louis
Wed 7/29
9:00 am-4:28 pm
1 stop6h 28m
Wilmington New Hanover County
Wed 8/5
10:20 am-3:58 pm
1 stop6h 38m
$241
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 6/1
4:40 pm-10:00 pm
1 stop4h 20m
Charlotte Douglas
Mon 6/8
4:40 pm-5:50 pm
Nonstop2h 10m
$249
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Mon 4/13
10:25 am-1:15 pm
Nonstop1h 50m
Raleigh-Durham
Tue 4/14
6:10 am-7:20 am
Nonstop2h 10m
$307
Quickest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 6/17
4:50 pm-7:40 pm
Nonstop1h 50m
Charlotte Douglas
Sun 8/23
1:35 pm-2:30 pm
Nonstop1h 55m
$312
Kansas CityRaleigh
MCI - RDU
MCIRDU
Kansas City
Tue 4/14
7:59 pm-11:30 pm
Nonstop2h 31m
Raleigh-Durham
Tue 4/21
7:00 am-8:56 am
Nonstop2h 56m
$317
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 6/17
6:00 am-1:50 pm
1 stop6h 50m
Charlotte Douglas
Sun 8/23
6:00 am-9:49 am
1 stop4h 49m
$319
St. LouisWilmington
STL - ILM
STLILM
Lambert-St Louis
Sat 8/22
7:30 am-3:28 pm
1 stop6h 58m
Wilmington New Hanover County
Tue 8/25
4:09 pm-9:22 pm
1 stop6h 13m
$321
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 4/30
4:00 pm-9:40 pm
1 stop4h 40m
Charlotte Douglas
Sun 5/3
8:50 pm-11:45 pm
1 stop3h 55m
$323
Kansas CityRaleigh
MCI - RDU
MCIRDU
Kansas City
Wed 5/27
6:38 pm-12:16 am
1 stop4h 38m
Raleigh-Durham
Wed 6/3
7:23 am-9:15 am
Nonstop2h 52m
$327
St. LouisRaleigh
STL - RDU
STLRDU
Lambert-St Louis
Fri 5/8
7:45 pm-10:35 pm
Nonstop1h 50m
Raleigh-Durham
Mon 5/11
6:10 pm-11:40 pm
1 stop6h 30m
$327
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
STL-RDU
MCI-RDU
STL-CLT
MCI-CLT
MCI-ILM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to North Carolina
USMO-USNC
STL-RDU
MCI-RDU
STL-CLT
MCI-CLT
What is the cheapest month to book a flight from Missouri to North Carolina?
Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in March is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to NC?
Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.
It’s optimal to fly from Missouri to North Carolina in the afternoon. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Missouri to North Carolina?
Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on March 14, 2026.
Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Missouri to North Carolina
Explore weekly flight availability from Missouri to North Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 22, 2026.
The most flights from USMO to USNC are scheduled on a Monday (6 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated March 22, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to North Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to North Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to North Carolina by cabin class
Find flights from Missouri to North Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and North Carolina flights
Browse other Missouri and North Carolina flight options. Last updated on March 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from North Carolina
Find the right flight back to Missouri after your stay in North Carolina
Missouri to North Carolina flights
Consider these flights traveling from Missouri to North Carolina.
Top 5 airlines flying from Missouri to North Carolina
Discover the top 5 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$342 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$134 | Average$225 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$170 | Average$375 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$187 | Average$357 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$358 | FlexibilityNo cancel fee | On-time69% |