HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
North Carolina

$55+ Cheap flights from Missouri to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RDU
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to North Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to North Carolina

Cheapest flights from Missouri to North Carolina
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:42 amSTL - RDU
1 stop12h 31mFrontier
Wed 12/3111:48 amRDU - STL
1 stop11h 45mFrontier
Deal found 11/11$111
This Frontier deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:30 pmSTL - CLT
1 stop15h 27mFrontier
Mon 12/1510:32 amCLT - STL
1 stop13h 01mFrontier
Deal found 11/11$111
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:48 amSTL - RDU
1 stop12h 25mFrontier
Sat 12/2711:40 amRDU - STL
1 stop23h 00mFrontier
Deal found 11/12$113
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:42 amSTL - RDU
1 stop12h 31mFrontier
Sat 1/311:40 amRDU - STL
1 stop23h 00mFrontier
Deal found 11/11$122
This Expedia deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:04 pmSTL - RDU
1 stop11h 08mFrontier
Fri 12/126:00 amRDU - STL
1 stop4h 47mFrontier
Deal found 11/13$124
This Frontier deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:13 pmMCI - RDU
1 stop10h 59mFrontier
Mon 12/156:10 amRDU - MCI
1 stop6h 41mFrontier
Deal found 11/11$124
This Frontier deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:30 pmSTL - CLT
1 stop5h 08mFrontier
Sun 12/710:33 pmCLT - STL
1 stop11h 26mFrontier
Deal found 11/12$124
This Frontier deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:47 amSTL - ORF
1 stop4h 33mFrontier
Sun 12/213:09 pmORF - STL
1 stop8h 24mFrontier
Deal found 11/12$127
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:20 amMCI - RDU
1 stop5h 48mFrontier
Thu 11/277:15 pmRDU - MCI
1 stop16h 03mFrontier
Deal found 11/11$131
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:57 amSTL - RDU
1 stop12h 16mFrontier
Wed 12/3111:48 amRDU - STL
1 stop11h 45mFrontier
Deal found 11/11$134
This Frontier deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:30 pmSTL - CLT
1 stop5h 08mFrontier
Sun 12/710:33 pmCLT - STL
1 stop11h 26mFrontier
Deal found 11/12$138
This Frontier deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:54 amSTL - RDU
1 stop5h 50mFrontier
Sun 12/146:00 amRDU - STL
1 stop4h 47mFrontier
Deal found 11/12$142

Cheap flight deals from Missouri to North Carolina

Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$111
(Kiwi.com)

One-way from

$55
(Priceline)

Popular in

August

Cheapest in

October

Average price

$374

Good round-trip deal

$329 or less

Good one-way deal

$164 or less
Provider with most accurate pricing for Lambert-St Louis-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Raleigh-Durham flights.
Search Deals
From Missouri to North Carolina
Search Deals
One-way flight from Missouri to North Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Missouri to North Carolina.
Search Deals
Price to beat on a one-way flight from Missouri to North Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.

Fly from

Missouri

Fly to

North Carolina

Route

Depart

Return

Price

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Mon 1/12

5:11 pm-4:05 pm

1 stop21h 54m

Raleigh-Durham

Wed 1/14

2:53 pm-10:34 pm

1 stop8h 41m

$110

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Thu 12/11

12:04 pm-12:12 am

1 stop11h 08m

Raleigh-Durham

Fri 12/12

6:00 am-9:47 am

1 stop4h 47m

$124

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Mon 12/1

4:13 pm-9:50 am

1 stop16h 37m

Charlotte Douglas

Sat 12/20

9:02 pm-10:33 pm

1 stop26h 31m

$152

St. LouisNorfolk

STL - ORF

STLORF

Lambert-St Louis

Thu 11/27

3:14 pm-3:21 pm

1 stop23h 07m

Norfolk

Mon 12/1

10:28 am-11:57 pm

1 stop14h 29m

$167

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Fri 11/21

4:13 pm-8:14 am

1 stop15h 01m

Raleigh-Durham

Mon 11/24

12:05 pm-11:57 pm

1 stop12h 52m

$186

St. LouisRaleigh

STL - RDU

STLRDU

Lambert-St Louis

Wed 11/26

4:13 pm-8:24 am

1 stop15h 11m

Raleigh-Durham

Tue 12/2

8:14 pm-10:33 pm

1 stop27h 19m

$195

St. LouisKnoxville

STL - TYS

STLTYS

Lambert-St Louis

Thu 11/27

7:57 pm-3:53 pm

1 stop18h 56m

Knoxville McGhee Tyson

Mon 12/1

11:29 am-11:57 pm

1 stop13h 28m

$206

Kansas CityCharlotte

MCI - CLT

MCICLT

Kansas City

Wed 12/31

8:45 pm-11:22 am

1 stop13h 37m

Charlotte Douglas

Wed 1/7

9:34 pm-3:33 pm

1 stop18h 59m

$213

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Wed 12/3

6:52 am-9:49 am

Nonstop1h 57m

Charlotte Douglas

Sat 12/20

6:26 pm-7:30 pm

Nonstop2h 04m

$217

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

Tue 2/24

2:30 pm-5:15 pm

Nonstop1h 45m

Charlotte Douglas

Wed 2/25

8:25 am-9:35 am

Nonstop2h 10m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to North Carolina

What is the cheapest month to book a flight from Missouri to North Carolina?

Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in December is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to NC?

Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s optimal to fly from Missouri to North Carolina in the evening. By choosing this option you can save up to 35% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Missouri to North Carolina?

Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated November 13, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,017 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,051 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,109 reviews
Southwest
8.0
Very good
4,242 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to North Carolina flight route?

    Flights from Missouri to North Carolina have been viewed 4 times in the past calendar month.

  • How long is the flight from Missouri to North Carolina?

    Departing from Missouri to North Carolina will take you 1h 45m. Missouri and North Carolina are separated by a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to North Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $55. Users have also found prices from $98 and $109 on Spirit Airlines and Southwest, respectively.

  • Can I find deals for flights from Missouri to North Carolina that include hotel bookings?

    Yes. In addition to deals on Missouri to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to North Carolina.

  • Can I find deals for business class flights from Missouri to North Carolina?

    Yes. Cheapflights offers flight deals from Missouri to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to North Carolina?

    Currently, April is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $108). Flying from Missouri to North Carolina in December is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Los Angeles flights
LaGuardia to Fort Lauderdale flights
Newark to Miami flights
John F Kennedy Intl to Dallas/Fort Worth flights
John F Kennedy Intl to Orlando flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
LaGuardia to Miami flights
John F Kennedy Intl to West Palm Beach flights
LaGuardia to Dallas/Fort Worth flights
Los Angeles to Newark flights
Newark to Dallas/Fort Worth flights
San Francisco to John F Kennedy Intl flights
Dallas/Fort Worth to Newark flights
Newark to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Seattle to Los Angeles flights
Newark to West Palm Beach flights
Atlanta to John F Kennedy Intl flights
O'Hare Intl to John F Kennedy Intl flights
Dallas/Fort Worth to Las Vegas flights
John F Kennedy Intl to San Francisco flights
Newark to Las Vegas flights
San Francisco to Newark flights
O'Hare Intl to Las Vegas flights
Los Angeles to Seattle flights
John F Kennedy Intl to Tampa flights
Los Angeles to LaGuardia flights
Hobby to LaGuardia flights
San Francisco to Las Vegas flights
Los Angeles to Honolulu flights
Fort Lauderdale to John F Kennedy Intl flights
Boston to Fort Lauderdale flights
Seattle to Las Vegas flights
Atlanta to LaGuardia flights
Newark to Orlando flights
John F Kennedy Intl to Atlanta flights
LaGuardia to Orlando flights
LaGuardia to Hobby flights
Los Angeles to Dallas/Fort Worth flights
John F Kennedy Intl to O'Hare Intl flights
O'Hare Intl to Sky Harbor Intl flights
Newark to San Francisco flights
Los Angeles to San Francisco flights
Hobby to Newark flights
San Francisco to Los Angeles flights

Top 6 airlines flying from Missouri to North Carolina

Discover the top 6 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$128Average$219FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$225FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$150Average$372FlexibilityNo cancel feeOn-time63%
DeltaCheapest$157Average$341FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$170Average$386FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$264Average$399FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.