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North Carolina

$92+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated September 11, 2025.

Round-trip from

$193
(American Airlines)

One-way from

$92
(Southwest)

Popular in

December

Cheapest in

September

Average price

$318

Good round-trip deal

$309 or less

Good one-way deal

$179 or less
From Des Moines to North Carolina
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One-way flight from Des Moines to North Carolina
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Highest demand for flights based on searches. 6% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Des Moines to North Carolina.
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Price to beat on a one-way flight from Des Moines to North Carolina.
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Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:22 pmDSM - TYS
1 stop4h 28mAmerican Airlines
Sat 11/16:47 pmTYS - DSM
1 stop5h 29mAmerican Airlines
Deal found 9/10$193
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:35 pmDSM - RDU
1 stop3h 55mSouthwest
Sat 10/46:55 amRDU - DSM
1 stop6h 15mSouthwest
Deal found 9/10$197
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:05 pmDSM - TYS
2 stops9h 54mUnited Airlines
Sat 11/88:26 amTYS - DSM
1 stop6h 53mUnited Airlines
Deal found 9/10$198
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/69:20 amDSM - RDU
1 stop25h 10mMultiple Airlines
Wed 10/86:30 amRDU - DSM
1 stop16h 15mMultiple Airlines
Deal found 9/10$204
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:30 amDSM - RDU
1 stop11h 42mMultiple Airlines
Wed 10/86:30 amRDU - DSM
1 stop16h 15mMultiple Airlines
Deal found 9/11$211
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/412:55 pmDSM - RDU
1 stop9h 20mSouthwest
Tue 10/76:55 pmRDU - DSM
1 stop3h 55mSouthwest
Deal found 9/10$216
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:30 amDSM - TYS
1 stop9h 14mAllegiant Air
Thu 10/99:50 pmTYS - DSM
1 stop11h 40mAllegiant Air
Deal found 9/11$218
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:22 pmDSM - ORF
1 stop4h 32mAmerican Airlines
Sat 10/256:26 amORF - DSM
1 stop7h 12mAmerican Airlines
Deal found 9/11$219
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:00 amDSM - RDU
1 stop4h 13mAmerican Airlines
Sat 10/47:16 pmRDU - DSM
1 stop4h 50mAmerican Airlines
Deal found 9/10$219
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:48 pmDSM - MYR
1 stop5h 48mAmerican Airlines
Tue 10/214:47 pmMYR - DSM
1 stop7h 29mAmerican Airlines
Deal found 9/10$219
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/298:25 amDSM - CLT
1 stop29h 43mMultiple Airlines
Wed 10/110:46 amCLT - DSM
1 stop24h 05mMultiple Airlines
Deal found 9/9$219
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:00 amDSM - ORF
1 stop5h 05mAmerican Airlines
Sat 11/18:30 amORF - DSM
1 stop5h 08mAmerican Airlines
Deal found 9/10$220

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Des Moines

Fly to

North Carolina

Route

Depart

Return

Price

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 10/25

6:22 pm-11:50 pm

1 stop4h 28m

Knoxville McGhee Tyson

Sat 11/1

6:47 pm-11:16 pm

1 stop5h 29m

$193

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 11/5

1:05 pm-11:59 pm

2 stops9h 54m

Knoxville McGhee Tyson

Sat 11/8

8:26 am-2:19 pm

1 stop6h 53m

$198

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Wed 2/11

6:10 am-11:05 am

1 stop3h 55m

Raleigh-Durham

Tue 2/17

6:40 pm-10:15 pm

1 stop4h 35m

$206

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 10/2

6:30 am-4:44 pm

1 stop9h 14m

Knoxville McGhee Tyson

Thu 10/9

9:50 pm-8:30 am

1 stop11h 40m

$218

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 10/7

5:42 pm-10:54 pm

1 stop4h 12m

Myrtle Beach Intl

Tue 10/14

4:47 pm-11:16 pm

1 stop7h 29m

$219

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 10/7

6:07 am-11:56 am

1 stop4h 49m

Myrtle Beach Intl

Tue 10/21

12:18 pm-5:02 pm

1 stop5h 44m

$219

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Sat 10/25

6:00 am-12:05 pm

1 stop5h 05m

Norfolk

Sat 11/1

8:30 am-12:38 pm

1 stop5h 08m

$220

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 10/22

4:45 pm-9:30 pm

1 stop3h 45m

Charlotte Douglas

Wed 11/5

12:55 pm-9:35 pm

1 stop9h 40m

$227

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 11/5

3:39 pm-12:08 am

1 stop7h 29m

Knoxville McGhee Tyson

Sat 11/8

6:18 pm-10:59 pm

1 stop5h 41m

$232

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 11/19

6:01 pm-12:08 am

1 stop5h 07m

Knoxville McGhee Tyson

Sat 11/22

12:09 pm-4:41 pm

1 stop5h 32m

$232

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/8

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to North Carolina?

    Departing from Des Moines to North Carolina will take you 3h 55m. Airlines will cover a distance of 890 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $92. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Raleigh-Durham or Des Moines - Norfolk when deciding on the best route from Des Moines to North Carolina.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to North Carolina

Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$332FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$426FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$238Average$369FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$386FlexibilityNo cancel feeOn-time69%

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