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North Carolina

$85+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$201
(Booking.com)

One-way from

$85
(Mytrip)

Popular in

June

Cheapest in

September

Average price

$366

Good round-trip deal

$352 or less

Good one-way deal

$203 or less
Provider with most accurate pricing for Des Moines-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Raleigh-Durham flights.
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From Des Moines to North Carolina
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One-way flight from Des Moines to North Carolina
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Highest demand for flights based on searches. 1% potential increase in price ($7 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Des Moines to North Carolina.
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Price to beat on a one-way flight from Des Moines to North Carolina.
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Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Booking.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:41 pmDSM - RDU
1 stop24h 55mFrontier
Sun 11/165:21 pmRDU - DSM
1 stop21h 26mFrontier
Deal found 10/25$201
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - RDU
2 stops18h 20mMultiple Airlines
Sun 12/79:58 amRDU - DSM
1 stop30h 00mMultiple Airlines
Deal found 10/28$220
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/51:56 pmDSM - RDU
2 stops9h 16mMultiple Airlines
Sun 12/79:58 amRDU - DSM
1 stop30h 00mMultiple Airlines
Deal found 10/28$236
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/610:38 amDSM - CLT
1 stop20h 19mMultiple Airlines
Sun 12/75:44 pmCLT - DSM
1 stop26h 19mMultiple Airlines
Deal found 10/27$239
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:00 amDSM - TYS
1 stop28h 01mAllegiant Air
Sun 11/169:00 amTYS - DSM
1 stop6h 01mAllegiant Air
Deal found 10/25$248
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:40 amDSM - GSO
1 stop4h 23mAmerican Airlines
Wed 12/176:08 amGSO - DSM
1 stop6h 34mAmerican Airlines
Deal found 10/26$248
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:28 pmDSM - RDU
2 stops15h 24mMultiple Airlines
Mon 12/152:14 pmRDU - DSM
1 stop7h 55mMultiple Airlines
Deal found 10/26$248
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:05 pmDSM - AVL
1 stop5h 06mAmerican Airlines
Wed 12/1711:36 amAVL - DSM
1 stop5h 49mAmerican Airlines
Deal found 10/26$248
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:00 amDSM - MYR
1 stop23h 20mMultiple Airlines
Fri 11/146:15 amMYR - DSM
2 stops9h 40mMultiple Airlines
Deal found 10/25$254
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:17 amDSM - AVL
2 stops7h 50mDelta
Wed 12/171:58 pmAVL - DSM
1 stop4h 49mDelta
Deal found 10/26$254
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:40 amDSM - CLT
1 stop13h 28mMultiple Airlines
Fri 11/145:45 amCLT - DSM
1 stop10h 10mMultiple Airlines
Deal found 10/26$254
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:35 amDSM - AVL
1 stop4h 36mDelta
Sat 11/156:12 pmAVL - DSM
1 stop5h 21mDelta
Deal found 10/26$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Des Moines

Fly to

North Carolina

Route

Depart

Return

Price

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Fri 12/5

1:56 pm-12:12 am

2 stops9h 16m

Raleigh-Durham

Sun 12/7

9:58 am-2:58 pm

1 stop30h 00m

$236

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Fri 11/14

8:00 am-1:01 pm

1 stop28h 01m

Knoxville McGhee Tyson

Sun 11/16

9:00 am-2:01 pm

1 stop6h 01m

$248

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 12/10

5:40 am-11:03 am

1 stop4h 23m

Greensboro/H. Point

Wed 12/17

6:08 am-11:42 am

1 stop6h 34m

$248

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Wed 12/10

6:17 am-3:07 pm

2 stops7h 50m

Asheville Regional

Wed 12/17

1:58 pm-5:47 pm

1 stop4h 49m

$254

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Sun 11/9

5:35 am-11:11 am

1 stop4h 36m

Asheville Regional

Sat 11/15

6:12 pm-10:33 pm

1 stop5h 21m

$259

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

Thu 1/15

4:25 pm-10:57 pm

1 stop5h 32m

Wilmington New Hanover County

Sun 1/18

5:51 pm-11:23 pm

1 stop6h 32m

$259

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 12/23

11:14 am-8:29 pm

1 stop8h 15m

Charlotte Douglas

Mon 1/5

12:17 pm-7:44 pm

1 stop8h 27m

$266

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 11/10

8:00 am-8:20 am

1 stop23h 20m

Myrtle Beach Intl

Wed 11/12

11:13 am-10:00 am

2 stops23h 47m

$270

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 12/4

2:56 pm-8:33 am

1 stop16h 37m

Knoxville McGhee Tyson

Fri 12/5

12:45 pm-11:12 pm

1 stop11h 27m

$271

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 12/4

2:56 pm-4:55 pm

1 stop24h 59m

Raleigh-Durham

Mon 12/8

6:10 am-9:13 pm

2 stops16h 03m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, November is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $145). Flying from Des Moines to North Carolina in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

It’s typically best to fly out from Des Moines to North Carolina in the evening. Doing so could potentially save you 56% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated October 28, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,994 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,001 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,240 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to North Carolina?

    Departing from Des Moines to North Carolina will take you 4h 23m. Airlines will cover a distance of 827 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $131. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Raleigh-Durham, Des Moines - Charlotte Douglas or Des Moines - Knoxville McGhee Tyson when deciding on the best route from Des Moines to North Carolina.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $145). Flying from Des Moines to North Carolina in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to North Carolina

Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$329FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$426FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$248Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$386FlexibilityNo cancel feeOn-time69%

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