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North Carolina

$87+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:26 pmDSM - GSO
1 stop4h 30mAmerican Airlines
Thu 1/157:40 amGSO - DSM
1 stop4h 32mAmerican Airlines
Deal found 12/10$294
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:34 amDSM - AVL
1 stop6h 39mDelta
Tue 1/66:15 pmAVL - DSM
1 stop5h 14mDelta
Deal found 12/11$334
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:35 amDSM - GSO
1 stop4h 16mUnited Airlines
Wed 12/175:32 pmGSO - DSM
1 stop5h 05mUnited Airlines
Deal found 12/10$354
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:56 pmDSM - RDU
1 stop5h 55mAmerican Airlines
Fri 1/26:37 amRDU - DSM
1 stop6h 49mAmerican Airlines
Deal found 12/10$357
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:24 pmDSM - GSO
1 stop7h 05mAmerican Airlines
Fri 1/165:43 pmGSO - DSM
1 stop6h 40mAmerican Airlines
Deal found 12/11$362
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:31 amDSM - AVL
2 stops37h 33mAllegiant Air
Mon 1/56:40 amAVL - DSM
1 stop9h 18mAllegiant Air
Deal found 12/11$365
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:34 amDSM - GSO
1 stop4h 49mDelta
Fri 1/165:22 amGSO - DSM
1 stop6h 18mDelta
Deal found 12/10$371
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:00 amDSM - TYS
1 stop28h 52mAllegiant Air
Fri 12/196:00 amTYS - DSM
1 stop16h 13mAllegiant Air
Deal found 12/10$377
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:21 pmDSM - TYS
1 stop25h 53mAllegiant Air
Fri 12/196:00 amTYS - DSM
1 stop16h 13mAllegiant Air
Deal found 12/10$391
This Frontier deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:14 amDSM - CLT
1 stop8h 15mFrontier
Fri 1/212:17 pmCLT - DSM
1 stop8h 27mFrontier
Deal found 12/11$392
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:52 pmDSM - CLT
1 stop12h 12mAmerican Airlines
Sat 1/311:42 amCLT - DSM
Nonstop2h 32mAmerican Airlines
Deal found 12/10$393
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:00 amDSM - GSO
1 stop7h 34mUnited Airlines
Mon 12/295:26 pmGSO - DSM
1 stop5h 14mUnited Airlines
Deal found 12/9$394

Find flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$231
(American Airlines)

One-way from

$87
(Expedia)

Popular in

December

Cheapest in

September

Average price

$427

Good round-trip deal

$352 or less

Good one-way deal

$233 or less
Provider with most accurate pricing for Des Moines-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Raleigh-Durham flights.
Search Deals
From Des Moines to North Carolina
Search Deals
One-way flight from Des Moines to North Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to North Carolina.
Search Deals
Price to beat on a one-way flight from Des Moines to North Carolina.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Des Moines

Fly to

North Carolina

Route

Depart

Return

Price

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Fri 2/27

6:00 am-2:07 pm

1 stop7h 07m

Asheville Regional

Mon 3/2

2:37 pm-10:04 pm

1 stop8h 27m

$249

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Fri 2/20

7:01 am-5:54 pm

2 stops9h 53m

Asheville Regional

Mon 2/23

1:46 pm-8:06 pm

1 stop7h 20m

$254

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Sun 1/25

2:58 pm-6:38 pm

1 stop26h 40m

Norfolk

Sun 2/1

7:33 pm-10:19 am

2 stops15h 46m

$265

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

Thu 1/15

4:25 pm-10:57 pm

1 stop5h 32m

Wilmington New Hanover County

Sun 1/18

5:51 pm-11:23 pm

1 stop6h 32m

$268

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 1/10

5:58 pm-4:42 pm

1 stop21h 44m

Charlotte Douglas

Tue 1/13

7:43 pm-5:24 pm

2 stops22h 41m

$269

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Sun 1/25

2:58 pm-2:13 pm

1 stop22h 15m

Raleigh-Durham

Sun 2/1

6:10 am-9:21 pm

2 stops40h 11m

$287

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 1/25

4:30 pm-7:20 pm

3 stops25h 50m

Myrtle Beach Intl

Sun 2/1

8:15 pm-10:19 am

2 stops15h 04m

$289

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sun 12/21

6:26 pm-11:56 pm

1 stop4h 30m

Greensboro/H. Point

Thu 1/15

7:40 am-11:12 am

1 stop4h 32m

$294

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 1/25

2:58 pm-8:11 am

1 stop16h 13m

Charlotte Douglas

Sun 2/1

1:24 pm-10:46 pm

1 stop10h 22m

$297

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 2/11

1:16 pm-11:57 pm

2 stops9h 41m

Myrtle Beach Intl

Wed 2/18

6:52 am-1:07 pm

1 stop7h 15m

$298

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, January is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $146). Flying from Des Moines to North Carolina in December is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s typically best to fly out from Des Moines to North Carolina in the evening. Doing so could potentially save you 56% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to North Carolina?

    Departing from Des Moines to North Carolina will take you 4h 23m. Airlines will cover a distance of 654 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $126. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Knoxville McGhee Tyson or Des Moines - Raleigh-Durham when deciding on the best route from Des Moines to North Carolina.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $146). Flying from Des Moines to North Carolina in December is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to North Carolina

Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$216Average$417FlexibilityNo cancel feeOn-time63%
DeltaCheapest$216Average$336FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$351FlexibilityNo cancel feeOn-time69%

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