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North Carolina

$97+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated July 29, 2025.

Round-trip from

$220
(Mytrip)

One-way from

$97
(Mytrip)

Popular in

March

Cheapest in

September

Average price

$409

Good round-trip deal

$305 or less

Good one-way deal

$168 or less
From Des Moines to North Carolina
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One-way flight from Des Moines to North Carolina
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Des Moines to North Carolina.
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Price to beat on a one-way flight from Des Moines to North Carolina.
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Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/224:29 pmDSM - CLT
2 stops14h 36mMultiple Airlines
Mon 8/252:52 pmCLT - DSM
1 stop6h 49mMultiple Airlines
Deal found 7/28$220
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/243:23 pmDSM - TYS
1 stop26h 02mFrontier
Sun 8/318:33 pmTYS - DSM
1 stop18h 50mFrontier
Deal found 7/28$225
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:24 pmDSM - ORF
1 stop7h 54mAmerican Airlines
Thu 11/63:13 pmORF - DSM
1 stop7h 56mAmerican Airlines
Deal found 7/29$237
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:15 amDSM - RDU
1 stop8h 32mUnited Airlines
Sat 8/235:35 pmRDU - DSM
1 stop5h 10mUnited Airlines
Deal found 7/27$237
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:52 amDSM - MYR
1 stop6h 11mDelta
Tue 10/2112:20 pmMYR - DSM
1 stop8h 00mDelta
Deal found 7/27$237
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:35 amDSM - CLT
1 stop7h 00mSouthwest
Sat 9/610:35 amCLT - DSM
1 stop5h 25mSouthwest
Deal found 7/29$242
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:20 pmDSM - RDU
1 stop21h 17mFrontier
Sun 8/245:32 pmRDU - DSM
1 stop21h 51mFrontier
Deal found 7/29$245
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:25 pmDSM - CLT
1 stop25h 18mFrontier
Thu 10/25:20 pmCLT - DSM
1 stop21h 20mFrontier
Deal found 7/27$245
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/203:49 pmDSM - TYS
1 stop7h 30mAmerican Airlines
Sun 8/246:07 pmTYS - DSM
1 stop7h 07mAmerican Airlines
Deal found 7/28$249
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/302:12 pmDSM - GSO
1 stop6h 44mDelta
Mon 9/16:04 amGSO - DSM
1 stop4h 33mDelta
Deal found 7/27$249
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/37:00 amDSM - RDU
1 stop8h 02mAmerican Airlines
Thu 9/48:00 amRDU - DSM
1 stop6h 05mAmerican Airlines
Deal found 7/29$252
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2011:35 amDSM - TYS
1 stop4h 25mUnited Airlines
Sun 8/245:45 amTYS - DSM
2 stops9h 25mUnited Airlines
Deal found 7/28$254

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Des Moines

Fly to

North Carolina

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 8/22

4:29 pm-8:05 am

2 stops14h 36m

Charlotte Douglas

Mon 8/25

2:52 pm-8:41 pm

1 stop6h 49m

$220

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sun 8/24

3:23 pm-6:25 pm

1 stop26h 02m

Knoxville McGhee Tyson

Sun 8/31

8:33 pm-2:23 pm

1 stop18h 50m

$225

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Tue 11/4

1:24 pm-10:18 pm

1 stop7h 54m

Norfolk

Thu 11/6

3:13 pm-10:09 pm

1 stop7h 56m

$237

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Wed 8/20

6:15 am-3:47 pm

1 stop8h 32m

Raleigh-Durham

Sat 8/23

5:35 pm-9:45 pm

1 stop5h 10m

$237

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 10/7

10:52 am-6:03 pm

1 stop6h 11m

Myrtle Beach Intl

Tue 10/21

12:20 pm-7:20 pm

1 stop8h 00m

$237

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Fri 8/22

6:20 pm-4:37 pm

1 stop21h 17m

Raleigh-Durham

Sun 8/24

5:32 pm-2:23 pm

1 stop21h 51m

$245

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 9/25

2:25 pm-4:43 pm

1 stop25h 18m

Charlotte Douglas

Thu 10/2

5:20 pm-1:40 pm

1 stop21h 20m

$245

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 8/20

3:49 pm-12:19 am

1 stop7h 30m

Knoxville McGhee Tyson

Sun 8/24

6:07 pm-12:14 am

1 stop7h 07m

$249

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sat 8/30

2:12 pm-9:56 pm

1 stop6h 44m

Greensboro/H. Point

Mon 9/1

6:04 am-9:37 am

1 stop4h 33m

$249

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 8/20

11:35 am-5:00 pm

1 stop4h 25m

Knoxville McGhee Tyson

Sun 8/24

5:45 am-2:10 pm

2 stops9h 25m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated July 29, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,979 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Allegiant Air
7.2
Good
702 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $107. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Myrtle Beach Intl or Des Moines - Greensboro/H. Point when deciding on the best route from Des Moines to North Carolina.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to North Carolina

Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$238Average$363FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$276Average$391FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$296Average$422FlexibilityNo cancel feeOn-time63%

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