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$272+ Cheap flights from Panama City (PTY) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Panama City to Indiana

Cheapest flights from Panama City to Indiana
Explore the most affordable flight options available from Panama City to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:55 pmPTY - SDF
2 stops15h 55mAmerican Airlines
Mon 1/126:00 amSDF - PTY
1 stop9h 38mAmerican Airlines
Deal found 12/15$536
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:55 amPTY - ORD
1 stop18h 25mAvianca
Tue 12/304:10 pmORD - PTY
1 stop17h 20mAvianca
Deal found 12/16$561
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:55 amPTY - SDF
2 stops13h 35mUnited Airlines
Mon 1/125:35 amSDF - PTY
2 stops14h 03mUnited Airlines
Deal found 12/15$569
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:45 amPTY - ORD
1 stop11h 35mAvianca
Wed 1/1410:20 pmORD - PTY
1 stop14h 40mAvianca
Deal found 12/16$590
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:25 amPTY - ORD
1 stop9h 35mMultiple Airlines
Mon 1/55:00 amORD - PTY
2 stops28h 30mMultiple Airlines
Deal found 12/15$596
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:55 amPTY - ORD
1 stop18h 25mAvianca
Tue 12/304:10 pmORD - PTY
1 stop17h 20mAvianca
Deal found 12/17$601
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:53 pmPTY - SDF
2 stops22h 37mAmerican Airlines
Thu 1/87:20 pmSDF - PTY
2 stops20h 18mAmerican Airlines
Deal found 12/17$604
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:53 pmPTY - IND
2 stops19h 43mAmerican Airlines
Fri 1/95:30 amIND - PTY
2 stops10h 08mAmerican Airlines
Deal found 12/16$604
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:45 amPTY - ORD
1 stop11h 35mAvianca
Fri 1/210:20 pmORD - PTY
1 stop9h 30mAvianca
Deal found 12/17$611
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:55 amPTY - SDF
1 stop27h 11mUnited Airlines
Sun 1/43:25 pmSDF - PTY
1 stop25h 42mUnited Airlines
Deal found 12/17$613
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:35 amPTY - IND
1 stop8h 32mUnited Airlines
Fri 1/99:00 amIND - PTY
1 stop8h 07mUnited Airlines
Deal found 12/16$621
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:00 amPTY - IND
1 stop10h 33mDelta
Fri 1/96:00 amIND - PTY
1 stop7h 55mDelta
Deal found 12/16$634

Find flight deals from Panama City to Indiana

Keep the following information in mind while searching for Panama City to Indiana flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$393
(Kiwi.com)

One-way from

$272
(Avianca Connect)

Popular in

August

Cheapest in

December

Average price

$516
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
Search Deals
From Panama City Tocumen Intl to Indiana
Search Deals
One-way flight from Panama City Tocumen Intl to Indiana
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Panama City to Indiana that are best for you.

Fly from

Panama City

Fly to

Indiana

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/30

9:33 pm-8:18 am

1 stop11h 45m

Chicago O'Hare Intl

Fri 2/6

6:57 pm-8:06 am

1 stop12h 09m

$397

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 5/1

10:55 pm-8:14 pm

2 stops20h 19m

Louisville Intl

Mon 5/11

6:00 pm-4:12 pm

2 stops23h 12m

$449

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 1/31

4:41 pm-10:23 am

2 stops17h 42m

Louisville Intl

Sat 2/7

2:05 pm-2:45 pm

2 stops24h 40m

$451

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 2/18

4:41 pm-1:23 pm

2 stops20h 42m

Louisville Intl

Sat 2/21

5:35 am-8:02 pm

2 stops14h 27m

$463

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 3/3

4:41 pm-10:48 am

1 stop18h 07m

Indianapolis

Wed 3/18

9:00 am-4:07 pm

1 stop8h 07m

$505

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/16

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Tue 1/20

10:20 pm-4:55 pm

1 stop17h 35m

$555

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 1/14

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Sun 1/25

10:20 pm-2:00 pm

1 stop14h 40m

$555

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/16

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Wed 1/21

10:20 pm-4:55 pm

1 stop17h 35m

$555

Panama CityCincinnati

PTY - CVG

PTYCVG

Panama City Tocumen Intl

Thu 1/22

4:41 pm-10:49 am

1 stop18h 08m

Cincinnati Cinci./N. Kentucky

Mon 1/26

6:25 am-5:07 pm

1 stop10h 42m

$567

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 2/1

7:50 pm-11:47 pm

3 stops28h 57m

Chicago O'Hare Intl

Sun 2/8

5:15 am-2:00 pm

3 stops31h 45m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 49 results
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Best time to book a flight from Panama City to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indiana

What is the cheapest month to book a flight from Panama City to Indiana?

Currently, February is the cheapest month in which you can book a flight from Panama City to Indiana (average of $295). Flying from Panama City to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IN?

Find hourly flight availability from Panama City to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Panama City to Indiana in the evening. By choosing this option you can save up to 37% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Panama City to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Indiana?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Indiana.

  • How long is the flight from Panama City to Indiana?

    Departing from Panama City to Indiana will take you 7h 47m. There are 2316 mi between Panama City and Indiana. This flight may include one or multiple stops.

  • What are the most popular routes from Panama City to Indiana?

    Most travelers choose Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway or Panama City Tocumen Intl - Indianapolis when deciding on the best route from Panama City to Indiana.

  • Can I find deals for flights from Panama City to Indiana that include hotel bookings?

    Yes. In addition to deals on Panama City to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indiana.

  • Can I find deals for business class flights from Panama City to Indiana?

    Yes. Cheapflights offers flight deals from Panama City to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Indiana?

    Currently, February is the cheapest month in which you can book a flight from Panama City to Indiana (average of $295). Flying from Panama City to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Indiana

Discover the top 2 airlines that operate flights from Panama City to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$344Average$590FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$650FlexibilityNo cancel feeOn-time69%

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