HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indiana

$220+ Cheap flights from Panama City (PTY) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Indiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Indiana

Keep the following information in mind while searching for Panama City to Indiana flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$393
(Priceline)

One-way from

$220
(Trip.com)

Popular in

January

Cheapest in

June

Average price

$568
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
Search Deals
From Panama City Tocumen Intl to Indiana
Search Deals
One-way flight from Panama City Tocumen Intl to Indiana
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from Panama City to Indiana

Cheapest flights from Panama City to Indiana
Explore the most affordable flight options available from Panama City to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Priceline deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/273:20 amPTY - ORD
1 stop9h 55mAvianca
Wed 6/43:45 pmORD - PTY
2 stops18h 40mAvianca
Deal found 4/30$393
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/288:01 amPTY - ORD
1 stop9h 40mMultiple Airlines
Sun 6/18:17 amORD - PTY
1 stop11h 12mMultiple Airlines
Deal found 4/29$423
This eDestinos deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/17:55 amPTY - ORD
1 stop16h 18mUnited Airlines
Mon 6/306:00 amORD - PTY
1 stop8h 14mUnited Airlines
Deal found 4/30$427
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/162:23 pmPTY - SDF
1 stop7h 32mDelta
Mon 6/306:00 amSDF - PTY
1 stop8h 08mDelta
Deal found 4/30$477
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/67:55 amPTY - ORD
Nonstop5h 52mCopa Airlines
Wed 6/183:07 pmORD - PTY
Nonstop5h 28mCopa Airlines
Deal found 4/29$480
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/82:23 pmPTY - MDW
1 stop21h 30mDelta
Sat 7/2610:26 amMDW - PTY
1 stop8h 37mDelta
Deal found 4/29$485
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/282:13 pmPTY - ORD
1 stop9h 45mDelta
Thu 6/125:05 pmORD - PTY
2 stops26h 25mDelta
Deal found 4/29$485
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/193:30 pmPTY - CVG
1 stop18h 21mUnited Airlines
Mon 6/2311:53 amCVG - PTY
1 stop7h 44mUnited Airlines
Deal found 4/29$503
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/163:30 pmPTY - SDF
1 stop29h 22mUnited Airlines
Mon 6/306:08 pmSDF - PTY
2 stops21h 06mUnited Airlines
Deal found 4/30$505
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:40 pmPTY - IND
1 stop7h 37mAmerican Airlines
Sun 9/76:34 amIND - PTY
1 stop6h 51mAmerican Airlines
Deal found 4/30$514
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/191:50 pmPTY - CVG
2 stops19h 58mAmerican Airlines
Mon 6/237:10 pmCVG - PTY
1 stop18h 50mAmerican Airlines
Deal found 4/30$518
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/153:40 pmPTY - SDF
1 stop7h 44mAmerican Airlines
Fri 12/125:16 pmSDF - PTY
2 stops20h 09mAmerican Airlines
Deal found 4/30$528

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Panama City to Indiana that are best for you.

Fly from

Panama City

Fly to

Indiana

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 5/27

3:20 am-1:15 pm

1 stop9h 55m

Chicago O'Hare Intl

Wed 6/4

3:45 pm-10:25 am

2 stops18h 40m

$393

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 5/28

8:01 am-5:41 pm

1 stop9h 40m

Chicago O'Hare Intl

Sun 6/1

8:17 am-7:29 pm

1 stop11h 12m

$423

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 6/1

7:55 am-12:13 am

1 stop16h 18m

Chicago O'Hare Intl

Mon 6/30

6:00 am-2:14 pm

1 stop8h 14m

$427

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 6/16

2:23 pm-10:55 pm

1 stop7h 32m

Louisville Intl

Mon 6/30

6:00 am-1:08 pm

1 stop8h 08m

$477

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 6/6

7:55 am-1:47 pm

Nonstop5h 52m

Chicago O'Hare Intl

Wed 6/18

3:07 pm-8:35 pm

Nonstop5h 28m

$480

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 7/8

2:23 pm-12:29 pm

2 stops22h 06m

Chicago Midway

Fri 7/25

6:00 am-1:03 pm

1 stop7h 03m

$485

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 5/28

2:13 pm-9:51 am

2 stops19h 38m

Chicago O'Hare Intl

Fri 6/13

7:05 am-7:30 pm

2 stops12h 25m

$485

Panama CityCincinnati

PTY - CVG

PTYCVG

Panama City Tocumen Intl

Thu 6/19

3:30 pm-10:51 am

1 stop18h 21m

Cincinnati Cinci./N. Kentucky

Mon 6/23

11:53 am-6:37 pm

1 stop7h 44m

$503

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 6/16

3:30 pm-9:52 pm

1 stop29h 22m

Louisville Intl

Mon 6/30

6:08 pm-2:14 pm

2 stops21h 06m

$505

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Fri 8/29

3:40 pm-12:17 am

1 stop7h 37m

Indianapolis

Sun 9/7

6:34 am-12:25 pm

1 stop6h 51m

$514

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 35 results
1
2
3
4

Best time to book a flight from Panama City to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indiana

What is the cheapest month to book a flight from Panama City to Indiana?

Currently, August is the cheapest month in which you can book a flight from Panama City to Indiana (average of $297). Flying from Panama City to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IN?

Find hourly flight availability from Panama City to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Indiana as you normally would.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines and Aeromexico from Panama City to Indiana. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,414 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Aeromexico
7.5
Good
1,698 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Indiana?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Indiana.

  • What are the cheapest airlines to fly from Panama City to Indiana one-way?

    For one-way options, check prices for Avianca. According to our data, you can fly for as low as $269. Users have also found prices from $322 and $344 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Panama City to Indiana?

    Most travelers choose Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Indianapolis or Panama City Tocumen Intl - Chicago Midway when deciding on the best route from Panama City to Indiana.

  • Can I find deals for flights from Panama City to Indiana that include hotel bookings?

    Yes. In addition to deals on Panama City to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indiana.

  • Can I find deals for business class flights from Panama City to Indiana?

    Yes. Cheapflights offers flight deals from Panama City to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Indiana (average of $297). Flying from Panama City to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Miami flights
Panama City to John F Kennedy Intl flights
Panama City to Newark flights
Panama City to Orlando flights
Panama City to Los Angeles flights
Panama City to LaGuardia flights
Panama City to Tampa flights
Panama City to Atlanta flights
Panama City to O'Hare Intl flights
Panama City to Boston flights
Panama City to Hobby flights
Panama City to Fort Lauderdale flights
Panama City to San Francisco flights
Panama City to George Bush Intcntl flights
Panama City to Dulles Intl flights
Panama City to Dallas/Fort Worth flights
Panama City to Las Vegas flights
Panama City to Ontario flights
Panama City to Austin flights
Panama City to Baltimore flights
Panama City to Hartford flights
Panama City to Honolulu flights
Panama City to Cleveland flights
Panama City to Indianapolis flights
Panama City to Raleigh flights
Panama City to Denver flights
Panama City to Salt Lake City flights
Panama City to New Orleans flights
Panama City to San Antonio flights
Panama City to Seattle flights
Panama City to Nashville flights
Panama City to Fayetteville flights
Panama City to Charlotte flights
Panama City to Minneapolis flights
Panama City to Philadelphia flights
Panama City to Reagan-National flights
Panama City to San Diego flights
Panama City to Asheville flights
Panama City to St. Louis flights
Panama City to Tallahassee flights
Panama City to Pittsburgh flights
Panama City to Jacksonville flights
Panama City to Kansas City flights
Panama City to Santa Ana flights
Panama City to Albuquerque flights
Panama City to West Palm Beach flights
Panama City to Chattanooga flights

Top 3 airlines flying from Panama City to Indiana

Discover the top 3 airlines that operate flights from Panama City to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$411Average$505FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$412Average$610FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$423Average$593FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.