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$277+ Cheap flights from Panama City (PTY) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Panama City to Indiana

Keep the following information in mind while searching for Panama City to Indiana flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$418
(Copa Airlines)

One-way from

$277
(Kiwi.com)

Popular in

August

Cheapest in

December

Average price

$595
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
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From Panama City Tocumen Intl to Indiana
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One-way flight from Panama City Tocumen Intl to Indiana
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Highest demand for flights based on searches. 11% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Panama City to Indiana

Cheapest flights from Panama City to Indiana
Explore the most affordable flight options available from Panama City to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Sun 1/112:13 pmORD - PTY
Nonstop5h 22mCopa Airlines
Deal found 11/3$418
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:37 pmPTY - MDW
1 stop9h 03mDelta
Fri 11/289:34 amMDW - PTY
2 stops9h 25mDelta
Deal found 11/3$424
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:00 amPTY - ORD
1 stop8h 13mDelta
Fri 1/25:30 amORD - PTY
1 stop13h 30mDelta
Deal found 11/3$424
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:50 pmPTY - ORD
1 stop10h 47mAmerican Airlines
Wed 12/107:00 amORD - PTY
1 stop7h 42mAmerican Airlines
Deal found 11/3$433
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:56 amPTY - ORD
Nonstop5h 56mCopa Airlines
Fri 1/92:13 pmORD - PTY
Nonstop5h 22mCopa Airlines
Deal found 11/3$434
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:43 pmPTY - ORD
2 stops17h 21mAmerican Airlines
Sun 12/78:55 pmORD - PTY
2 stops15h 52mAmerican Airlines
Deal found 11/3$437
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:43 pmPTY - ORD
1 stop8h 54mAmerican Airlines
Sat 1/247:30 pmORD - PTY
1 stop19h 08mAmerican Airlines
Deal found 11/3$440
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Mon 12/87:33 amORD - PTY
Nonstop5h 27mCopa Airlines
Deal found 11/2$444
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:50 amPTY - ORD
Nonstop5h 56mCopa Airlines
Sun 12/77:33 amORD - PTY
Nonstop5h 27mCopa Airlines
Deal found 11/3$450
This Gotogate deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:37 pmPTY - ORD
Nonstop5h 44mCopa Airlines
Sat 1/32:13 pmORD - PTY
Nonstop5h 22mCopa Airlines
Deal found 11/2$494
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:43 pmPTY - ORD
1 stop19h 22mAmerican Airlines
Mon 11/244:40 pmORD - PTY
1 stop20h 03mAmerican Airlines
Deal found 11/3$495
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:53 pmPTY - IND
2 stops19h 43mAmerican Airlines
Fri 1/95:30 amIND - PTY
2 stops10h 08mAmerican Airlines
Deal found 11/3$518

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Panama City to Indiana that are best for you.

Fly from

Panama City

Fly to

Indiana

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 2/1

7:20 pm-12:04 am

Nonstop5h 44m

Chicago O'Hare Intl

Fri 2/6

2:22 pm-8:35 pm

Nonstop5h 13m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Sun 12/7

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 12/20

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Sun 1/11

2:13 pm-8:35 pm

Nonstop5h 22m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 12/23

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Fri 1/2

2:13 pm-8:35 pm

Nonstop5h 22m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 1/14

8:10 am-12:46 pm

Nonstop5h 36m

Chicago O'Hare Intl

Sun 1/25

2:13 pm-8:35 pm

Nonstop5h 22m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 12/20

5:37 pm-10:21 pm

Nonstop5h 44m

Chicago O'Hare Intl

Mon 1/5

7:35 am-2:00 pm

Nonstop5h 25m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 11/21

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Fri 11/28

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 11/20

7:20 pm-12:05 am

Nonstop5h 45m

Chicago O'Hare Intl

Mon 11/24

2:07 pm-8:35 pm

Nonstop5h 28m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 12/30

7:56 am-12:52 pm

Nonstop5h 56m

Chicago O'Hare Intl

Thu 1/29

7:35 am-2:00 pm

Nonstop5h 25m

$418

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 1/26

7:40 pm-12:24 am

Nonstop5h 44m

Chicago O'Hare Intl

Sun 2/1

2:22 pm-8:35 pm

Nonstop5h 13m

$418

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 58 results
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Best time to book a flight from Panama City to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indiana

What is the cheapest month to book a flight from Panama City to Indiana?

Currently, June is the cheapest month in which you can book a flight from Panama City to Indiana (average of $304). Flying from Panama City to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IN?

Find hourly flight availability from Panama City to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

It’s optimal to fly from Panama City to Indiana in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated November 3, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Panama City to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Indiana?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Indiana.

  • How long is the flight from Panama City to Indiana?

    Departing from Panama City to Indiana will take you 5h 44m. There are 2330 mi between Panama City and Indiana. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Panama City to Indiana one-way?

    For one-way options, check prices for Avianca. According to our data, you can fly for as low as $285. Users have also found prices from $307 and $322 on United Airlines and American Airlines, respectively.

  • What are the most popular routes from Panama City to Indiana?

    Most travelers choose Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway or Panama City Tocumen Intl - Indianapolis when deciding on the best route from Panama City to Indiana.

  • Can I find deals for flights from Panama City to Indiana that include hotel bookings?

    Yes. In addition to deals on Panama City to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indiana.

  • Can I find deals for business class flights from Panama City to Indiana?

    Yes. Cheapflights offers flight deals from Panama City to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Indiana?

    Currently, June is the cheapest month in which you can book a flight from Panama City to Indiana (average of $304). Flying from Panama City to Indiana in September is currently the most expensive (average of $562). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Indiana

Discover the top 2 airlines that operate flights from Panama City to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$312Average$568FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$640FlexibilityNo cancel feeOn-time69%

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