Cheap flights from Des Moines to Gainesville (DSM - GNV) from $428

It’s generally more expensive to depart on a Thursday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

It’s typically best to fly out from Des Moines to Gainesville at noon. Doing so could potentially save you 12% on the flight price compared to flying in the morning, which is usually more expensive.

Delta and American Airlines are some of the carriers that may have flexible cancellation policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

Yes, there are multiple flights from Des Moines to Gainesville for under $500. The cheapest flight booked recently is on Delta for just $428, but on average you can expect to pay $623.

While on average a flight from Des Moines to Gainesville is generally $316, our data shows the cheapest flight currently is $229. When looking at the most popular route, (Des Moines - Gainesville Regional), you can expect to pay $428 for that flight.

DSM stands for Des Moines Airport, while GNV stands for Gainesville Regional Airport. These codes are often called IATA codes, a set of identifiers established by IATA (International Air Transport Association) that is widely used by airlines and the aviation industry.