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$150+ Cheap flights from Des Moines to Fresno (DSM - FAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FAT
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Des Moines to Fresno

Cheapest flights from Des Moines to Fresno
Explore the most affordable flight options available from Des Moines to Fresno. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:15 pm
DSM
-
FAT
2 stops8h 25m
Southwest
Wed 5/2012:35 pm
FAT
-
DSM
1 stop6h 40m
Southwest
Deal found 1/27$356
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:08 pm
DSM
-
FAT
1 stop7h 04m
American Airlines
Sat 2/216:00 am
FAT
-
DSM
1 stop5h 28m
American Airlines
Deal found 1/26$367
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:10 pm
DSM
-
FAT
2 stops6h 35m
Southwest
Wed 5/2012:35 pm
FAT
-
DSM
1 stop6h 40m
Southwest
Deal found 1/27$369
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:21 pm
DSM
-
FAT
2 stops42h 53m
Multiple Airlines
Thu 3/2610:21 pm
FAT
-
DSM
1 stop21h 43m
Multiple Airlines
Deal found 1/25$374
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:17 pm
DSM
-
FAT
1 stop5h 42m
United Airlines
Wed 5/205:00 am
FAT
-
DSM
1 stop5h 54m
United Airlines
Deal found 1/27$377
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:26 pm
DSM
-
FAT
1 stop9h 46m
American Airlines
Mon 3/91:05 pm
FAT
-
DSM
2 stops8h 35m
American Airlines
Deal found 1/26$379
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:10 pm
DSM
-
FAT
2 stops6h 35m
Southwest
Tue 5/196:30 am
FAT
-
DSM
2 stops12h 45m
Southwest
Deal found 1/27$380
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:21 pm
DSM
-
FAT
2 stops27h 10m
Multiple Airlines
Thu 3/2610:21 pm
FAT
-
DSM
1 stop21h 43m
Multiple Airlines
Deal found 1/25$388
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:25 pm
DSM
-
FAT
1 stop5h 55m
Southwest
Wed 5/1312:35 pm
FAT
-
DSM
1 stop6h 40m
Southwest
Deal found 1/26$389

Find flight deals from Des Moines to Fresno

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fresno (FAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$356
(Southwest)

One-way from

$150
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$530
Provider with most accurate pricing for Des Moines-Fresno Airterminal flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Fresno Airterminal flights.
Search Deals
From Des Moines to Fresno Airterminal
Search Deals
One-way flight from Des Moines to Fresno Airterminal
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Fresno that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Des Moines to Fresno that are best for you.

Fly from

Des Moines

Fly to

Fresno

Route

Depart

Return

Price

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Wed 5/13

5:17 pm-8:59 pm

1 stop5h 42m

Fresno Airterminal

Wed 5/20

5:00 am-12:54 pm

1 stop5h 54m

$377

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Thu 5/14

7:10 pm-11:45 pm

2 stops6h 35m

Fresno Airterminal

Tue 5/19

6:30 am-9:15 pm

2 stops12h 45m

$380

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Thu 5/14

7:10 pm-11:45 pm

2 stops6h 35m

Fresno Airterminal

Wed 5/20

6:30 am-5:55 pm

2 stops9h 25m

$387

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Wed 3/18

8:21 pm-9:31 pm

2 stops27h 10m

Fresno Airterminal

Thu 3/26

10:21 pm-10:04 pm

1 stop21h 43m

$388

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Fri 5/8

12:25 pm-4:20 pm

1 stop5h 55m

Fresno Airterminal

Wed 5/13

12:35 pm-9:15 pm

1 stop6h 40m

$389

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Wed 3/18

12:15 pm-5:00 pm

1 stop6h 45m

Fresno Airterminal

Mon 3/23

10:45 am-11:15 pm

2 stops10h 30m

$417

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Wed 3/25

8:21 pm-9:31 pm

2 stops27h 10m

$150

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Mon 3/23

8:21 pm-1:14 pm

2 stops42h 53m

$180

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Tue 3/24

5:00 am-9:18 am

1 stop6h 18m

$189

Des MoinesFresno

DSM - FAT

DSMFAT

Des Moines

Thu 3/26

6:23 pm-10:31 pm

1 stop6h 08m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 16 results
1
2

Compare providers for flights from Des Moines to Fresno

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fresno in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Fresno flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fresno flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fresno flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Fresno flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fresno flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Fresno

Have a flexible travel schedule? Discover the best time to fly to Fresno from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Fresno

Get insights into the airlines that provide service to Fresno. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fresno. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Des Moines to Fresno by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,205 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,197 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fresno. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Fresno?

    United Airlines and Southwest can get you from Des Moines to Fresno in just under 5h 42m. Your travel time can differ by up to 53m. There are 1428 mi between Des Moines and Fresno. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Fresno round-trip?

    American Airlines, at $296, was found to be the cheapest airline from Des Moines to Fresno.Alternate airlines to your destination round-trip include Southwest and United Airlines. Users have found that American Airlines is 37% cheaper than the other options available to this destination.

  • Can I find deals for flights from Des Moines to Fresno that include hotel bookings?

    Yes. In addition to deals on Des Moines to Fresno flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Fresno?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fresno.

  • Can I find deals for business class flights from Des Moines to Fresno?

    Yes. Cheapflights offers flight deals from Des Moines to Fresno by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Fresno?

Book flights to Fresno if you plan to visit one of these locations
Madera
Kingsburg
Oakhurst
Clovis
Bass Lake

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Top 3 airlines flying from Des Moines to Fresno

Discover the top 3 airlines that operate flights from Des Moines to Fresno. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$296Average$423FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$298Average$456FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$302Average$505FlexibilityNo cancel feeOn-time69%

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