HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida

$342+ Cheap flights from Florence, SC (FLO) to Florida

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MIA
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florence to Florida with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florence to Florida

Keep the following information in mind while searching for Florence to Florida flight deals. Data was last updated September 16, 2025.

Round-trip from

$346
(American Airlines)

One-way from

$342
(American Airlines)
From Florence to Florida
Search Deals
One-way flight from Florence to Florida
Search Deals

Find flight deals from Florence to Florida

Cheapest flights from Florence to Florida
Explore the most affordable flight options available from Florence to Florida. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:14 amFLO - MCO
2 stops13h 30mAmerican Airlines
Sat 10/412:11 pmMCO - FLO
2 stops11h 05mAmerican Airlines
Deal found 9/15$346
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:37 pmFLO - PBI
2 stops17h 38mAmerican Airlines
Sat 10/115:25 pmPBI - FLO
2 stops17h 21mAmerican Airlines
Deal found 9/15$395
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/182:29 pmFLO - MIA
1 stop6h 24mAmerican Airlines
Sat 10/255:18 amMIA - FLO
1 stop5h 28mAmerican Airlines
Deal found 9/14$404
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:14 amFLO - TPA
1 stop4h 10mAmerican Airlines
Sat 10/46:52 pmTPA - FLO
1 stop4h 24mAmerican Airlines
Deal found 9/15$407
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:15 amFLO - MCO
1 stop3h 52mAmerican Airlines
Sun 11/236:38 pmMCO - FLO
1 stop5h 03mAmerican Airlines
Deal found 9/15$411
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:28 amFLO - TPA
1 stop3h 38mAmerican Airlines
Tue 12/164:52 pmTPA - FLO
1 stop6h 01mAmerican Airlines
Deal found 9/14$411
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:14 amFLO - TPA
1 stop4h 04mAmerican Airlines
Sun 10/265:11 pmTPA - FLO
1 stop6h 52mAmerican Airlines
Deal found 9/14$435
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:29 amFLO - MIA
1 stop4h 49mAmerican Airlines
Tue 11/115:45 amMIA - FLO
1 stop5h 02mAmerican Airlines
Deal found 9/14$441
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:37 pmFLO - FLL
1 stop6h 13mAmerican Airlines
Sun 10/59:58 amFLL - FLO
1 stop6h 34mAmerican Airlines
Deal found 9/16$442
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:33 pmFLO - FLL
1 stop5h 50mAmerican Airlines
Sun 12/217:16 amFLL - FLO
1 stop5h 10mAmerican Airlines
Deal found 9/14$455
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/182:29 pmFLO - FLL
1 stop4h 06mAmerican Airlines
Sat 10/256:00 amFLL - FLO
1 stop4h 46mAmerican Airlines
Deal found 9/14$458
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1811:11 amFLO - PBI
1 stop5h 27mAmerican Airlines
Sat 10/256:01 amPBI - FLO
1 stop4h 45mAmerican Airlines
Deal found 9/14$458

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Florence to Florida that are best for you.

Fly from

Florence

Fly to

Florida

Route

Depart

Return

Price

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Tue 9/30

6:14 am-7:44 pm

2 stops13h 30m

Orlando

Sat 10/4

12:11 pm-11:16 pm

2 stops11h 05m

$346

FlorenceWest Palm Beach

FLO - PBI

FLOPBI

Florence

Sat 10/4

5:37 pm-11:15 am

2 stops17h 38m

Palm Beach Intl

Sat 10/11

5:25 pm-10:46 am

2 stops17h 21m

$395

FlorenceMiami

FLO - MIA

FLOMIA

Florence

Sat 10/18

2:29 pm-8:53 pm

1 stop6h 24m

Miami

Sat 10/25

5:18 am-10:46 am

1 stop5h 28m

$404

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Tue 9/30

6:14 am-10:24 am

1 stop4h 10m

Tampa

Sat 10/4

6:52 pm-11:16 pm

1 stop4h 24m

$407

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Wed 11/19

6:15 am-10:07 am

1 stop3h 52m

Orlando

Sun 11/23

6:38 pm-11:41 pm

1 stop5h 03m

$411

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Wed 11/19

10:29 am-5:16 pm

1 stop6h 47m

Tampa

Sun 11/23

1:50 pm-6:07 pm

1 stop4h 17m

$411

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 12/12

10:28 am-2:06 pm

1 stop3h 38m

Tampa

Tue 12/16

4:52 pm-10:53 pm

1 stop6h 01m

$411

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 10/24

6:14 am-10:18 am

1 stop4h 04m

Tampa

Sun 10/26

5:11 pm-12:03 am

1 stop6h 52m

$435

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 11/14

10:29 am-4:01 pm

1 stop5h 32m

Tampa

Fri 11/21

1:50 pm-6:07 pm

1 stop4h 17m

$435

FlorenceMiami

FLO - MIA

FLOMIA

Florence

Fri 11/7

10:29 am-3:18 pm

1 stop4h 49m

Miami

Tue 11/11

5:45 am-10:47 am

1 stop5h 02m

$441

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 28 results
1
2
3

Best time to book a flight from Florence to Florida

Have a flexible travel schedule? Discover the best time to fly to Florida from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Florida

What is the cheapest month to book a flight from Florence, South Carolina to Florida?

Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Florida (average of $232). Flying from Florence, South Carolina to Florida in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida

Get insights into the airlines that provide service to Florida. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida. Reviews last updated September 16, 2025.
See what other customers who have flown with American Airlines from Florence to Florida have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Florence to Florida. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Florida?

    Most people fly from Florence (FLO) if they book a flight from Florence to Florida. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Florida?

    There are many flights that can get you from Florence, South Carolina to Florida in 13h 30m. Fly via American Airlines to get the fastest option. Florence, South Carolina and Florida are separated by a distance of 408 mi.

  • What are the most popular routes from Florence, South Carolina to Florida?

    Most travelers choose Florence - Miami, Florence - Tampa or Florence - Orlando when deciding on the best route from Florence, South Carolina to Florida.

  • Can I find deals for flights from Florence to Florida that include hotel bookings?

    Yes. In addition to deals on Florence to Florida flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Florida?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Florida.

  • Can I find deals for business class flights from Florence to Florida?

    Yes. Cheapflights offers flight deals from Florence to Florida by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Florida?

    Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Florida (average of $232). Flying from Florence, South Carolina to Florida in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to Florida

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to LaGuardia flights
Charlotte to Newark flights
Charlotte to Boston flights
Charlotte to Las Vegas flights
Charlotte to O'Hare Intl flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Denver flights
Charlotte to Dulles Intl flights
Charlotte to Hobby flights
Charlotte to Orlando flights
Charlotte to Sky Harbor Intl flights
Charlotte to George Bush Intcntl flights
Charlotte to Fort Lauderdale flights
Charlotte to Miami flights
Charlotte to Los Angeles flights
Charleston to John F Kennedy Intl flights
Charlotte to Baltimore flights
Charleston to Newark flights
Charlotte to Minneapolis flights
Charlotte to Salt Lake City flights
Charlotte to Love Field flights
Charleston to LaGuardia flights
Greenville to John F Kennedy Intl flights
Charleston to O'Hare Intl flights
Savannah to John F Kennedy Intl flights
Greenville to Newark flights
Charlotte to Detroit flights
Charlotte to Seattle flights
Greenville to LaGuardia flights
Charlotte to Austin flights
Charlotte to Nashville flights
Charlotte to Midway flights
Charlotte to San Francisco flights
Savannah to Newark flights
Greenville to Dallas/Fort Worth flights
Charleston to Hobby flights
Charlotte to Philadelphia flights
Greenville to Denver flights
Savannah to LaGuardia flights
Charleston to Las Vegas flights
Charlotte to Reagan-National flights
Charleston to Denver flights
Charlotte to San Diego flights
Savannah to O'Hare Intl flights
Columbia to LaGuardia flights
Columbia to John F Kennedy Intl flights
Charlotte to Honolulu flights
Greenville to O'Hare Intl flights
Charlotte to Providence flights

Top airline flying from Florence to Florida

Discover the top airline that operate flights from Florence to Florida. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$310Average$446FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.