$367+ Cheap flights from Florida to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — FLO
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Florida to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Florida to FlorenceExplore the most affordable flight options available from Florida to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Florida to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:40 am -
1 stop5h 29m
Sat 10/245:09 am -
1 stop6h 06m
Deal found 9/13![American Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:48 am -
1 stop5h 06m
Tue 10/206:30 am -
1 stop5h 40m
Deal found 9/15![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:12 pm -
1 stop4h 46m
Wed 9/301:43 pm -
1 stop5h 44m
Deal found 9/11![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:52 am -
1 stop4h 26m
Wed 9/306:24 am -
1 stop4h 52m
Deal found 9/11![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:32 am -
1 stop3h 46m
Sat 10/31:43 pm -
1 stop4h 48m
Deal found 9/14![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:12 pm -
1 stop4h 46m
Sat 10/31:43 pm -
1 stop3h 39m
Deal found 9/13![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:29 pm -
1 stop6h 27m
Sun 11/85:09 am -
1 stop4h 15m
Deal found 9/11![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:22 pm -
1 stop6h 35m
Mon 10/192:34 pm -
1 stop5h 53m
Deal found 9/12![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:01 am -
1 stop5h 17m
Mon 9/141:43 pm -
1 stop5h 44m
Deal found 9/11![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 10/1710:11 am -
1 stop3h 58m
Sat 10/245:09 am -
1 stop4h 11m
Deal found 9/13![American Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:26 pm -
1 stop6h 28m
Tue 12/86:24 am -
1 stop4h 42m
Deal found 9/15![American Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:32 am -
1 stop3h 46m
Sun 10/42:36 pm -
1 stop4h 09m
Deal found 9/14![American Airlines logo]()
$582
Best flights from Florida to FlorenceDiscover carefully curated flight deals from Florida to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Florida to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:48 am -
1 stop5h 06m
Tue 10/206:30 am -
1 stop5h 40m
Deal found 9/15![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:12 pm -
1 stop4h 46m
Wed 9/301:43 pm -
1 stop5h 44m
Deal found 9/11![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:52 am -
1 stop4h 26m
Wed 9/306:24 am -
1 stop4h 52m
Deal found 9/11![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:32 am -
1 stop3h 46m
Sat 10/31:43 pm -
1 stop4h 48m
Deal found 9/14![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:12 pm -
1 stop4h 46m
Sat 10/31:43 pm -
1 stop3h 39m
Deal found 9/12![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:29 pm -
1 stop6h 27m
Sun 11/85:09 am -
1 stop4h 15m
Deal found 9/11![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:22 pm -
1 stop6h 35m
Mon 10/192:34 pm -
1 stop5h 53m
Deal found 9/12![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:50 pm -
1 stop4h 09m
Mon 12/76:24 am -
1 stop4h 42m
Deal found 9/15![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:50 pm -
1 stop4h 09m
Sun 12/65:09 am -
1 stop6h 21m
Deal found 9/15![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:02 pm -
1 stop4h 55m
Sun 10/115:09 am -
1 stop4h 06m
Deal found 9/10![American Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:44 pm -
1 stop4h 13m
Mon 10/122:34 pm -
1 stop4h 20m
Deal found 9/12![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 am -
1 stop6h 09m
Sun 10/115:09 am -
1 stop6h 35m
Deal found 9/14![American Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:11 am -
1 stop3h 58m
Sun 10/185:09 am -
1 stop4h 11m
Deal found 9/13![American Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:36 am -
1 stop3h 33m
Sun 10/115:09 am -
1 stop6h 11m
Deal found 9/14![American Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:27 am -
1 stop5h 51m
Tue 9/296:24 am -
1 stop5h 49m
Deal found 9/11![American Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:12 pm -
1 stop4h 46m
Tue 9/296:24 am -
1 stop3h 48m
Deal found 9/11![American Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:55 pm -
2 stops9h 03m
Tue 9/296:24 am -
1 stop3h 48m
Deal found 9/11![American Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:57 pm -
2 stops8h 01m
Sat 9/261:43 pm -
1 stop3h 39m
Deal found 9/14![American Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:43 pm -
1 stop4h 11m
Wed 12/93:37 pm -
1 stop6h 09m
Deal found 9/15![American Airlines logo]()
$682
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:49 pm -
2 stops7h 09m
Sun 10/42:36 pm -
1 stop6h 23m
Deal found 9/14![American Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:34 pm -
2 stops8h 23m
Mon 10/192:34 pm -
1 stop5h 25m
Deal found 9/14![American Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:56 am -
2 stops13h 03m
Wed 12/96:24 am -
2 stops17h 02m
Deal found 9/15![American Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:56 am -
2 stops13h 03m
Sat 12/56:24 am -
2 stops14h 54m
Deal found 9/15![American Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:27 am -
1 stop5h 51m
Sat 9/266:24 am -
1 stop5h 49m
Deal found 9/11![American Airlines logo]()
$776
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
2 stops6h 48m
Mon 9/281:43 pm -
2 stops10h 09m
Deal found 9/11![American Airlines logo]()
$863
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:22 pm -
1 stop6h 35m
Mon 10/125:09 am -
2 stops16h 01m
Deal found 9/12![American Airlines logo]()
$894
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:40 am -
1 stop5h 29m
Mon 10/125:09 am -
1 stop4h 06m
Deal found 9/10![American Airlines logo]()
$941
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:50 am -
2 stops7h 19m
Mon 10/125:09 am -
2 stops10h 37m
Deal found 9/12![American Airlines logo]()
$953
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:00 pm -
1 stop6h 58m
Sun 9/275:09 am -
2 stops6h 03m
Deal found 9/12![American Airlines logo]()
$1,075
Last-minute flights from Florida to FlorenceDiscover last-minute flight deals from Florida to Florence. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Florida to Florence. Data last updated September 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:12 pm -
1 stop4h 46m
Sat 10/31:43 pm -
1 stop3h 39m
Deal found 9/13![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:27 am -
1 stop5h 51m
Tue 9/296:24 am -
1 stop5h 49m
Deal found 9/11![American Airlines logo]()
$607
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:12 pm -
1 stop4h 46m
Wed 9/301:43 pm -
1 stop5h 44m
Deal found 9/11![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:52 am -
1 stop4h 26m
Wed 9/306:24 am -
1 stop4h 52m
Deal found 9/11![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:32 am -
1 stop3h 46m
Sat 10/31:43 pm -
1 stop4h 48m
Deal found 9/14![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:32 am -
1 stop3h 46m
Sun 10/42:36 pm -
1 stop4h 09m
Deal found 9/14![American Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:48 am -
1 stop5h 06m
Tue 10/206:30 am -
1 stop5h 40m
Deal found 9/15![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:44 pm -
1 stop4h 13m
Mon 10/122:34 pm -
1 stop4h 20m
Deal found 9/12![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:22 pm -
1 stop6h 35m
Mon 10/192:34 pm -
1 stop5h 53m
Deal found 9/12![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
1 stop6h 09m
Mon 10/195:09 am -
1 stop4h 02m
Deal found 9/14![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:40 am -
1 stop5h 29m
Sat 10/245:09 am -
1 stop6h 06m
Deal found 9/13![American Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:11 am -
1 stop3h 58m
Sat 10/245:09 am -
1 stop4h 11m
Deal found 9/13![American Airlines logo]()
$566
One-way flights from Florida to FlorenceSearch for one-way flight options from Florida to Florence. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Florida to Florence. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:13 pm -
2 stops19h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:03 am -
1 stop5h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:02 am -
1 stop4h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:27 pm -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
2 stops8h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$477
Find flight deals from Florida to Florence
Keep the following information in mind while searching for Florida to Florence flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $492 (American Airlines) |
One-way from | $367 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florida to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Florida to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Wed 9/23
8:03 am-1:18 pm
1 stop5h 15m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$416
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Sat 10/17
10:02 am-2:09 pm
1 stop4h 07m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$417
Quickest round-trip
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Thu 11/5
10:14 am-2:10 pm
1 stop3h 56m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$442
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Sun 10/18
5:30 pm-11:57 pm
1 stop6h 27m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$442
TampaFlorence
TPA Tampa - FLO Florence
TPAFLO
Tampa
Thu 10/1
4:27 pm-10:58 pm
1 stop6h 31m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$442
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Tue 10/6
9:48 am-2:54 pm
1 stop5h 06m
Florence
Tue 10/20
6:30 am-12:10 pm
1 stop5h 40m
$507
TampaFlorence
TPA Tampa - FLO Florence
TPAFLO
Tampa
Sat 9/26
6:12 pm-10:58 pm
1 stop4h 46m
Florence
Wed 9/30
1:43 pm-7:27 pm
1 stop5h 44m
$517
MiamiFlorence
MIA Miami - FLO Florence
MIAFLO
Miami
Sat 9/26
8:52 am-1:18 pm
1 stop4h 26m
Florence
Wed 9/30
6:24 am-11:16 am
1 stop4h 52m
$535
OrlandoFlorence
MCO Orlando - FLO Florence
MCOFLO
Orlando
Tue 9/29
9:32 am-1:18 pm
1 stop3h 46m
Florence
Sat 10/3
1:43 pm-6:31 pm
1 stop4h 48m
$537
TampaFlorence
TPA Tampa - FLO Florence
TPAFLO
Tampa
Tue 9/22
6:12 pm-10:58 pm
1 stop4h 46m
Florence
Sat 10/3
1:43 pm-5:22 pm
1 stop3h 39m
$537
Showing 1-10 of 34 resultsSorted by cheapest first
Best time to book a flight from Florida to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Florida with our price prediction graph.
MIA-FLO
MCO-FLO
TPA-FLO
FLL-FLO
SRQ-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florida to Florence
USFL-FLO
MIA-FLO
MCO-FLO
TPA-FLO
FLL-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Florida and Florence flights
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Florida to Florence flights
Consider these flights traveling from Florida to Florence.
Top airline flying from Florida to Florence
Discover the top airline that operate flights from Florida to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$430 | Average$550 | FlexibilityNo cancel fee | On-time71% |