How long is the flight from Fort Myers to Florence, South Carolina?

A quick flight from Fort Myers to Florence, South Carolina can take about 3h 56m. American Airlines provides one of the quickest options available for as low as $591. The distance from Fort Myers to Florence, South Carolina is about 542 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from RSW to FLO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Florence, South Carolina as you normally would.

Most accurate provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Fort Myers-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Fort Myers-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

Can I find deals for business class flights from Fort Myers to Florence?

Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$591+ Cheap Flights from Fort Myers to Florence, SC

Q: E

Most trusted provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Q: Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

Q: How can I find direct flights from Fort Myers to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

Q: Can I find deals for business class flights from Fort Myers to Florence?

Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Fort Myers to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Fort Myers to Florence

Cheapest

Best

Last-minute

Cheapest flights from Fort Myers to Florence
Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.

Thu 7/1610:00 am

RSW

FLO

1 stop4h 10m

American Airlines

Wed 7/222:35 pm

FLO

RSW

1 stop5h 58m

American Airlines

Deal found 7/12

$591

Fri 7/2412:06 pm

RSW

FLO

2 stops11h 31m

American Airlines

Sat 7/255:17 am

FLO

RSW

2 stops7h 24m

American Airlines

Deal found 7/12

$1,213

Find flight deals from Fort Myers to Florence

Most accurate provider	Expedia 1 star
Most trusted provider	Expedia 3 stars
Round-trip from	$591 (American Airlines)

Provider with most accurate pricing for Fort Myers SW Florida Intl-Florence flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Florence flights.

Search Deals

From Fort Myers SW Florida Intl to Florence

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Fort MyersFlorence

RSW - FLO

RSWFLO

Fort Myers SW Florida Intl

Fri 7/24

7:41 pm-11:37 pm

1 stop3h 56m

Florence

Sat 7/25

2:35 pm-6:51 pm

1 stop4h 16m

$591

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/12

Sorted by cheapest first

Most accurate provider: When it comes to deals on Fort Myers-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Fort Myers-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Fort Myers-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Fort Myers with our price prediction graph.

RSW-FLO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Fort Myers to Florence, South Carolina?
A quick flight from Fort Myers to Florence, South Carolina can take about 3h 56m. American Airlines provides one of the quickest options available for as low as $591. The distance from Fort Myers to Florence, South Carolina is about 542 mi.
Can I find deals for flights from Fort Myers to Florence that include hotel bookings?
Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.
Can I find deals for business class flights from Fort Myers to Florence?
Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Sumter

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Flights by cabin class

Florence flight routes

Other flight options

Popular flights

Alternative routes for Fort Myers to Florence

Fort Lauderdale to Charlotte flights

Orlando to Charlotte flights

Tampa to Charlotte flights

Miami to Charlotte flights

West Palm Beach to Charlotte flights

Tampa to Charleston flights

Fort Lauderdale to Charleston flights

Orlando to Myrtle Beach flights

Jacksonville to Charlotte flights

Orlando to Charleston flights

Miami to Charleston flights

Fort Lauderdale to Greenville flights

Tampa to Greenville flights

Fort Lauderdale to Myrtle Beach flights

Tampa to Myrtle Beach flights

Fort Myers to Charlotte flights

Miami to Greenville flights

Pensacola to Charlotte flights

Tampa to Savannah flights

Sarasota to Charleston flights

Fort Myers to Charleston flights

Sarasota to Charlotte flights

Fort Lauderdale to Savannah flights

Miami to Savannah flights

West Palm Beach to Charleston flights

Orlando to Columbia flights

Orlando to Savannah flights

Melbourne to Charlotte flights

Jacksonville to Augusta flights

Jacksonville to Greenville flights

West Palm Beach to Greenville flights

Fort Myers to Greenville flights

Tampa to Columbia flights

West Palm Beach to Myrtle Beach flights

Fort Myers to Savannah flights

West Palm Beach to Savannah flights

Pensacola to Savannah flights

Miami to Columbia flights

Sarasota to Greenville flights

Orlando to Greenville flights

Pensacola to Charleston flights

Tallahassee to Charlotte flights

Fort Lauderdale to Columbia flights

Miami to Myrtle Beach flights

Valparaiso to Charlotte flights

Fort Myers to Myrtle Beach flights

Daytona Beach to Charlotte flights

Gainesville to Charlotte flights

Pensacola to Greenville flights

Panama City to Charleston flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$591+ Cheap flights from Fort Myers to Florence, SC (RSW - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Fort Myers to Florence

Cheapest flights from Fort Myers to FlorenceExplore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.

Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.

Best flights from Fort Myers to FlorenceDiscover carefully curated flight deals from Fort Myers to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.

Discover carefully curated flight deals from Fort Myers to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.

Last-minute flights from Fort Myers to FlorenceDiscover last-minute flight deals from Fort Myers to Florence. Data last updated July 13, 2026 and is based on user searches.

Discover last-minute flight deals from Fort Myers to Florence. Data last updated July 13, 2026 and is based on user searches.

Find flight deals from Fort Myers to Florence

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Florence that are best for you.

Best time to book a flight from Fort Myers to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Fort Myers with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Fort Myers to Florence, South Carolina?

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

How can I find direct flights from Fort Myers to Florence?

Can I find deals for business class flights from Fort Myers to Florence?

Traveling to a place near Florence?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Fort Myers to Florence

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Fort Myers to Florence by cabin class

Find flights from Fort Myers to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Other flights to Florence

Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 13, 2026.

Fort Myers and Florence flights

Browse other Fort Myers and Florence flight options. Last updated on July 13, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Fort Myers to Florence
Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.

Best flights from Fort Myers to Florence
Discover carefully curated flight deals from Fort Myers to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.

Last-minute flights from Fort Myers to Florence
Discover last-minute flight deals from Fort Myers to Florence. Data last updated July 13, 2026 and is based on user searches.