How long is the flight from Fort Myers to Florence, South Carolina?

A quick flight from Fort Myers to Florence, South Carolina can take about 15h 39m. American Airlines provides one of the quickest options available for as low as $679. The distance from Fort Myers to Florence, South Carolina is about 542 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from RSW to FLO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Florence, South Carolina as you normally would.

Most accurate provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Fort Myers-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Fort Myers-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

Can I find deals for business class flights from Fort Myers to Florence?

Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$407+ Cheap Flights from Fort Myers to Florence, SC

Q: E

Most trusted provider : When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Q: Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

Q: How can I find direct flights from Fort Myers to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

Q: Can I find deals for business class flights from Fort Myers to Florence?

Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Cheap flight deals from Fort Myers to Florence

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Cheapest flights from Fort Myers to Florence
Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Wed 10/78:18 am -

2 stops15h 39m

Thu 10/85:09 am -

2 stops17h 43m

Deal found 9/5

$679

Find flight deals from Fort Myers to Florence

Most accurate provider	Expedia 1 star
Most trusted provider	Expedia 3 stars
Round-trip from	$679 (American Airlines)
One-way from	$407 (American Airlines)

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Fort MyersFlorence

RSW Fort Myers SW Florida Intl - FLO Florence

RSWFLO

Fort Myers SW Florida Intl

Tue 9/22

7:12 pm-1:18 pm

2 stops18h 06m

Florence

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$491

Fort MyersFlorence

RSW Fort Myers SW Florida Intl - FLO Florence

RSWFLO

Fort Myers SW Florida Intl

Wed 10/7

8:18 am-11:57 pm

2 stops15h 39m

Florence

Thu 10/8

5:09 am-10:52 pm

2 stops17h 43m

$679

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Most accurate provider: When it comes to deals on Fort Myers-Florence, South Carolina flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Fort Myers-Florence, South Carolina flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Fort Myers-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-Florence, South Carolina flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Fort Myers with our price prediction graph.

RSW-FLO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Fort Myers to Florence, South Carolina?
A quick flight from Fort Myers to Florence, South Carolina can take about 15h 39m. American Airlines provides one of the quickest options available for as low as $679. The distance from Fort Myers to Florence, South Carolina is about 542 mi.
Can I find deals for flights from Fort Myers to Florence that include hotel bookings?
Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.
Can I find deals for business class flights from Fort Myers to Florence?
Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$407+ Cheap flights from Fort Myers to Florence, SC (RSW - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Florence with Cheapflights

1. Tell us where you want to go

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Cheap flight deals from Fort Myers to Florence

Cheapest flights from Fort Myers to FlorenceExplore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Best flights from Fort Myers to FlorenceDiscover carefully curated flight deals from Fort Myers to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.

Discover carefully curated flight deals from Fort Myers to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.

Last-minute flights from Fort Myers to FlorenceDiscover last-minute flight deals from Fort Myers to Florence. Data last updated September 6, 2026 and is based on user searches.

Discover last-minute flight deals from Fort Myers to Florence. Data last updated September 6, 2026 and is based on user searches.

One-way flights from Fort Myers to FlorenceSearch for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.

Search for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.

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Use the filters below to find and compare flights from Fort Myers to Florence that are best for you.

Best time to book a flight from Fort Myers to Florence

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Related info for your journey

How long is the flight from Fort Myers to Florence, South Carolina?

Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

How can I find direct flights from Fort Myers to Florence?

Can I find deals for business class flights from Fort Myers to Florence?

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Cheapest flights from Fort Myers to Florence
Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Best flights from Fort Myers to Florence
Discover carefully curated flight deals from Fort Myers to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.

Last-minute flights from Fort Myers to Florence
Discover last-minute flight deals from Fort Myers to Florence. Data last updated September 6, 2026 and is based on user searches.

One-way flights from Fort Myers to Florence
Search for one-way flight options from Fort Myers to Florence. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.