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$442+ Cheap flights from Fort Myers to Florence, SC (RSW - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — FLO
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Fort Myers to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$442
(American Airlines)
From Fort Myers SW Florida Intl to Florence
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Find flight deals from Fort Myers to Florence

Cheapest flights from Fort Myers to Florence
Explore the most affordable flight options available from Fort Myers to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/167:30 pmRSW - FLO
1 stop4h 29mAmerican Airlines
Sun 7/205:07 amFLO - RSW
1 stop4h 00mAmerican Airlines
Deal found 7/1$442

Cheapflights Fare Finder

Customize your flight search to find flights from Fort Myers to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Fort Myers to Florence that are best for you.

Fly from

Fort Myers

Fly to

Florence

Route

Depart

Return

Price

Fort MyersFlorence

RSW - FLO

RSWFLO

Fort Myers SW Florida Intl

Wed 7/16

7:30 pm-11:59 pm

1 stop4h 29m

Florence

Sun 7/20

5:07 am-9:07 am

1 stop4h 00m

$442

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Fort Myers to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Florence

What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Fort Myers to Florence, South Carolina (average of $366). Flying from Fort Myers to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to FLO?

Find hourly flight availability from Fort Myers to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Florence, South Carolina as you normally would.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated July 3, 2025.
Read reviews from past customers who have flown American Airlines from Fort Myers to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Crew

8.0

Food

6.5

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Bama,Oct 2024

MIA - PNS

I paid for first class and it was nothing more than a 36" long curtain between first and business class, nothing extra, nothing fancy and a waste of money. Would have been better off just getting a regular seat and saving the money. Also had one of my eardrums rupture because of the take off and had to sit in uncomfortable pain with a bleeding ear the entire flight. Had to go to the doctor and it's been 5 days and still having difficulty hearing like it just happened.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Crew

8.0

Food

6.5

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Bama,Oct 2024

MIA - PNS

I paid for first class and it was nothing more than a 36" long curtain between first and business class, nothing extra, nothing fancy and a waste of money. Would have been better off just getting a regular seat and saving the money. Also had one of my eardrums rupture because of the take off and had to sit in uncomfortable pain with a bleeding ear the entire flight. Had to go to the doctor and it's been 5 days and still having difficulty hearing like it just happened.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Fort Myers to Florence, South Carolina round-trip?

    Currently priced at $442, American Airlines will fly you from Fort Myers to Florence, South Carolina and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Fort Myers to Florence that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Florence.

  • Can I find deals for business class flights from Fort Myers to Florence?

    Yes. Cheapflights offers flight deals from Fort Myers to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Fort Myers to Florence, South Carolina (average of $366). Flying from Fort Myers to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Fort Myers to Florence

Discover the top airline that operate flights from Fort Myers to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$365Average$472FlexibilityNo cancel feeOn-time71%

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