
Keep the following information in mind while searching for Fort Myers to South Carolina flight deals. Data was last updated November 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $118 (Kiwi.com) |
One-way from | $53 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $587 |
Fly from
Fly to
Route
Depart
Return
Fort MyersCharleston
RSW Fort Myers SW Florida Intl - CHS Charleston
RSWCHS
Fort Myers SW Florida Intl
Fri 11/20
6:30 am-8:04 am
Nonstop1h 34m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersCharleston
RSW Fort Myers SW Florida Intl - CHS Charleston
RSWCHS
Fort Myers SW Florida Intl
Fri 12/11
6:05 am-7:39 am
Nonstop1h 34m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersCharleston
RSW Fort Myers SW Florida Intl - CHS Charleston
RSWCHS
Fort Myers SW Florida Intl
Fri 12/11
6:27 pm-12:04 am
1 stop5h 37m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersGreenville
RSW Fort Myers SW Florida Intl - GSP Greenville
RSWGSP
Fort Myers SW Florida Intl
Thu 11/19
8:15 am-10:02 am
Nonstop1h 47m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersGreenville
RSW Fort Myers SW Florida Intl - GSP Greenville
RSWGSP
Fort Myers SW Florida Intl
Sun 11/22
8:15 am-10:02 am
Nonstop1h 47m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersCharleston
RSW Fort Myers SW Florida Intl - CHS Charleston
RSWCHS
Fort Myers SW Florida Intl
Mon 2/15
12:48 pm-2:22 pm
Nonstop1h 34m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersCharleston
RSW Fort Myers SW Florida Intl - CHS Charleston
RSWCHS
Fort Myers SW Florida Intl
Sun 12/20
4:35 pm-11:40 pm
1 stop7h 05m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersMyrtle Beach
RSW Fort Myers SW Florida Intl - MYR Myrtle Beach Intl
RSWMYR
Fort Myers SW Florida Intl
Wed 12/16
7:30 am-1:15 pm
1 stop5h 45m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersMyrtle Beach
RSW Fort Myers SW Florida Intl - MYR Myrtle Beach Intl
RSWMYR
Fort Myers SW Florida Intl
Tue 12/15
5:20 am-10:07 am
1 stop4h 47m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Fort MyersMyrtle Beach
RSW Fort Myers SW Florida Intl - MYR Myrtle Beach Intl
RSWMYR
Fort Myers SW Florida Intl
Tue 12/15
7:00 am-6:25 pm
2 stops11h 25m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Everything you need to know about your flight from Fort Myers to South Carolina
Food
Overall
Entertainment
Crew
Comfort
Boarding
Reviews
James,Oct 2026
RSW - RDU
Food
Overall
Entertainment
Crew
Comfort
Boarding
Reviews
James,Oct 2026
RSW - RDU
Food
Overall
Entertainment
Crew
Comfort
Boarding
Reviews
James,Oct 2026
RSW - RDU
Food
Overall
Entertainment
Crew
Comfort
Boarding
Reviews
James,Oct 2026
RSW - RDU
Find useful and relevant information for your journey from Fort Myers to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$88 | Average$203 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$207 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$468 | FlexibilityNo cancel fee | On-time71% |