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$325+ Cheap flights from Wisconsin to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — FLO
Jan 25 — Feb 11
Sun 1/25
Sun 2/1
1 adult, Economy
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Cheap flight deals from Wisconsin to Florence

Cheapest flights from Wisconsin to Florence
Explore the most affordable flight options available from Wisconsin to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:20 amMSP - FLO
1 stop5h 06mAmerican Airlines
Thu 1/15:15 amFLO - MSP
1 stop5h 11mAmerican Airlines
Deal found 12/26$395

Find flight deals from Wisconsin to Florence

Keep the following information in mind while searching for Wisconsin to Florence flight deals. Data was last updated December 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$325
(American Airlines)
Provider with most accurate pricing for Milwaukee-Mitchell-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Florence flights.
Search Deals
From Wisconsin to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Wisconsin to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from Wisconsin to Florence that are best for you.

Fly from

Wisconsin

Fly to

Florence

Route

Depart

Return

Price

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Sat 5/23

9:22 am-2:07 pm

1 stop3h 45m

Florence

Sat 5/30

5:22 am-9:25 am

1 stop5h 03m

$325

AppletonFlorence

ATW - FLO

ATWFLO

Appleton Intl

Sat 2/28

10:43 am-11:58 pm

2 stops12h 15m

Florence

Sat 4/25

5:13 am-10:44 am

2 stops6h 31m

$335

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Sat 1/10

4:47 pm-11:11 pm

1 stop5h 24m

Florence

Wed 1/14

5:36 pm-9:26 pm

1 stop4h 50m

$363

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 12/30

6:20 am-12:26 pm

1 stop5h 06m

Florence

Thu 1/1

5:15 am-9:26 am

1 stop5h 11m

$395

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 1/15

4:00 pm-10:43 pm

1 stop5h 43m

Florence

Sun 1/18

5:36 pm-9:26 pm

1 stop4h 50m

$427

AppletonFlorence

ATW - FLO

ATWFLO

Appleton Intl

Sat 2/28

10:43 am-11:58 pm

2 stops12h 15m

Florence

Sun 4/26

5:13 am-10:44 am

2 stops6h 31m

$539

AppletonFlorence

ATW - FLO

ATWFLO

Appleton Intl

Sun 3/1

6:43 am-5:45 pm

2 stops10h 02m

Florence

Sun 4/26

5:13 am-10:44 am

2 stops6h 31m

$555

AppletonFlorence

ATW - FLO

ATWFLO

Appleton Intl

Sun 3/1

6:43 am-5:45 pm

2 stops10h 02m

Florence

Sat 4/25

11:13 am-9:46 pm

1 stop11h 33m

$758

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Best time to book a flight from Wisconsin to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Wisconsin with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wisconsin to Florence

What is the cheapest month to book a flight from Wisconsin to Florence, South Carolina?

Currently, May is the cheapest month in which you can book a flight from Wisconsin to Florence, South Carolina (average of $118). Flying from Wisconsin to Florence, South Carolina in December is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Wisconsin to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Wisconsin?

    Most people fly into Florence (FLO) if they book a flight to Florence from Wisconsin. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Wisconsin to Florence, South Carolina?

    Airlines like American Airlines fly from Wisconsin to Florence, South Carolina in about 3h 45m. The time it takes to get you to your destination can typically vary by up to . Wisconsin and Florence, South Carolina are separated by a distance of 697 mi.

  • What are the most popular routes from Wisconsin to Florence, South Carolina?

    While some choose either Appleton Intl - Florence or Milwaukee-Mitchell - Florence, Chicago O'Hare Intl - Florence is the most popular route from Wisconsin to Florence, South Carolina.

  • Can I find deals for flights from Wisconsin to Florence that include hotel bookings?

    Yes. In addition to deals on Wisconsin to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wisconsin to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wisconsin to Florence.

  • Can I find deals for business class flights from Wisconsin to Florence?

    Yes. Cheapflights offers flight deals from Wisconsin to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wisconsin to Florence, South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Wisconsin to Florence, South Carolina (average of $118). Flying from Wisconsin to Florence, South Carolina in December is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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