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Florence

$163+ Cheap flights from Wisconsin to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — FLO
Mar 24 — Mar 311
Tue 3/24
Tue 3/31
1 adult, Economy
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Cheap flight deals from Wisconsin to Florence

Cheapest flights from Wisconsin to Florence
Explore the most affordable flight options available from Wisconsin to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.

This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:50 am
ORD
-
FLO
1 stop5h 00m
American Airlines
Wed 4/16:20 pm
FLO
-
ORD
1 stop6h 46m
American Airlines
Deal found 2/20$325
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:39 am
ORD
-
FLO
1 stop6h 11m
American Airlines
Tue 5/196:15 am
FLO
-
ORD
1 stop4h 57m
American Airlines
Deal found 2/17$335
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:39 am
ORD
-
FLO
1 stop6h 11m
American Airlines
Sun 5/35:20 am
FLO
-
ORD
1 stop6h 24m
American Airlines
Deal found 2/18$371
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:00 pm
ORD
-
FLO
1 stop6h 57m
American Airlines
Sat 3/216:25 pm
FLO
-
ORD
1 stop6h 33m
American Airlines
Deal found 2/17$380
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:50 am
ORD
-
FLO
1 stop4h 20m
American Airlines
Tue 6/92:35 pm
FLO
-
ORD
1 stop6h 13m
American Airlines
Deal found 2/20$401
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:59 am
ORD
-
FLO
1 stop5h 11m
American Airlines
Sat 5/302:35 pm
FLO
-
ORD
1 stop6h 13m
American Airlines
Deal found 2/18$405
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:45 pm
ORD
-
FLO
1 stop6h 12m
American Airlines
Fri 5/295:09 am
FLO
-
ORD
1 stop6h 39m
American Airlines
Deal found 2/18$417
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:59 am
ORD
-
FLO
1 stop5h 11m
American Airlines
Sat 5/305:09 am
FLO
-
ORD
1 stop4h 55m
American Airlines
Deal found 2/18$425
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:59 am
MSP
-
FLO
1 stop7h 08m
American Airlines
Tue 11/106:33 pm
FLO
-
MSP
1 stop5h 35m
American Airlines
Deal found 2/18$427
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:10 am
MKE
-
FLO
1 stop5h 59m
American Airlines
Tue 9/811:15 am
FLO
-
MKE
1 stop5h 39m
American Airlines
Deal found 2/20$446
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:10 am
MSP
-
FLO
1 stop6h 40m
American Airlines
Sun 3/226:20 pm
FLO
-
MSP
1 stop5h 59m
American Airlines
Deal found 2/18$451
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:37 pm
MKE
-
FLO
1 stop4h 20m
American Airlines
Thu 3/126:20 pm
FLO
-
MKE
1 stop6h 25m
American Airlines
Deal found 2/21$457

Find flight deals from Wisconsin to Florence

Keep the following information in mind while searching for Wisconsin to Florence flight deals. Data was last updated February 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$325
(American Airlines)

One-way from

$163
(American Airlines)
Provider with most accurate pricing for Milwaukee-Mitchell-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Florence flights.
Search Deals
From Wisconsin to Florence
Search Deals
One-way flight from Wisconsin to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wisconsin to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Wisconsin to Florence that are best for you.

Fly from

Wisconsin

Fly to

Florence

Route

Depart

Return

Price

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Wed 3/25

11:50 am-5:50 pm

1 stop5h 00m

Florence

Wed 4/1

6:20 pm-12:06 am

1 stop6h 46m

$325

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Thu 5/14

8:39 am-3:50 pm

1 stop6h 11m

Florence

Tue 5/19

6:15 am-10:12 am

1 stop4h 57m

$335

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Fri 5/1

8:39 am-3:50 pm

1 stop6h 11m

Florence

Sun 5/3

5:20 am-10:44 am

1 stop6h 24m

$371

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Wed 3/18

4:00 pm-11:57 pm

1 stop6h 57m

Florence

Sat 3/21

6:25 pm-11:58 pm

1 stop6h 33m

$380

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Wed 3/18

10:10 am-5:50 pm

1 stop6h 40m

Florence

Sun 3/22

6:20 pm-11:19 pm

1 stop5h 59m

$451

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Fri 3/6

6:35 pm-11:57 pm

1 stop4h 22m

Florence

Tue 3/10

5:58 pm-12:06 am

1 stop7h 08m

$457

AppletonFlorence

ATW - FLO

ATWFLO

Appleton Intl

Fri 3/13

1:25 pm-11:57 pm

2 stops9h 32m

Florence

Sun 3/15

6:20 pm-11:59 pm

1 stop6h 39m

$460

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Sun 3/8

6:44 am-5:50 pm

2 stops10h 06m

Florence

Thu 3/12

5:16 am-10:52 am

1 stop6h 36m

$462

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Thu 3/5

6:22 pm-11:57 pm

1 stop4h 35m

Florence

Mon 3/9

6:20 pm-12:06 am

1 stop6h 46m

$467

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Thu 3/19

5:05 pm-11:57 pm

1 stop5h 52m

Florence

Mon 3/23

6:20 pm-11:19 pm

1 stop5h 59m

$483

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 14 results
1
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Best time to book a flight from Wisconsin to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Wisconsin with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wisconsin to Florence

What is the cheapest month to book a flight from Wisconsin to Florence, South Carolina?

Currently, May is the cheapest month in which you can book a flight from Wisconsin to Florence, South Carolina (average of $118). Flying from Wisconsin to Florence, South Carolina in December is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Wisconsin to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Wisconsin?

    Most people fly into Florence (FLO) if they book a flight to Florence from Wisconsin. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Wisconsin to Florence, South Carolina?

    Airlines like American Airlines fly from Wisconsin to Florence, South Carolina in about 5h. The time it takes to get you to your destination can typically vary by up to . Wisconsin and Florence, South Carolina are separated by a distance of 697 mi.

  • What are the most popular routes from Wisconsin to Florence, South Carolina?

    While some choose either Minneapolis St Paul - Florence or Appleton Intl - Florence, Chicago O'Hare Intl - Florence is the most popular route from Wisconsin to Florence, South Carolina.

  • Can I find deals for flights from Wisconsin to Florence that include hotel bookings?

    Yes. In addition to deals on Wisconsin to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wisconsin to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wisconsin to Florence.

  • Can I find deals for business class flights from Wisconsin to Florence?

    Yes. Cheapflights offers flight deals from Wisconsin to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wisconsin to Florence, South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Wisconsin to Florence, South Carolina (average of $118). Flying from Wisconsin to Florence, South Carolina in December is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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