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$229+ Cheap flights from Wisconsin to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — FLO
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Wisconsin to Florence

Keep the following information in mind while searching for Wisconsin to Florence flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$355
(American Airlines)

One-way from

$229
(American Airlines)
Provider with most accurate pricing for Milwaukee-Mitchell-Florence flight deals.
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Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Florence flights.
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From Wisconsin to Florence
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One-way flight from Wisconsin to Florence
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Find flight deals from Wisconsin to Florence

Cheapest flights from Wisconsin to Florence
Explore the most affordable flight options available from Wisconsin to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:44 pmORD - FLO
1 stop6h 09mAmerican Airlines
Tue 12/96:15 amFLO - ORD
1 stop5h 38mAmerican Airlines
Deal found 11/2$393
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:48 pmMKE - FLO
1 stop4h 15mAmerican Airlines
Thu 11/206:33 pmFLO - MKE
1 stop6h 29mAmerican Airlines
Deal found 11/1$457
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2411:06 amMSP - FLO
1 stop5h 03mAmerican Airlines
Sun 11/305:15 amFLO - MSP
1 stop5h 04mAmerican Airlines
Deal found 11/2$524
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:39 amATW - FLO
2 stops12h 14mAmerican Airlines
Sat 12/136:31 pmFLO - ATW
1 stop5h 16mAmerican Airlines
Deal found 11/2$637
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:00 amORD - FLO
1 stop4h 45mAmerican Airlines
Wed 11/126:15 amFLO - ORD
1 stop5h 21mAmerican Airlines
Deal found 11/1$671

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wisconsin to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Wisconsin to Florence that are best for you.

Fly from

Wisconsin

Fly to

Florence

Route

Depart

Return

Price

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Tue 4/14

6:54 am-2:10 pm

1 stop6h 16m

Florence

Sat 4/18

5:13 am-8:48 am

1 stop4h 35m

$355

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Tue 12/2

3:44 pm-10:53 pm

1 stop6h 09m

Florence

Tue 12/9

6:15 am-10:53 am

1 stop5h 38m

$393

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Tue 3/17

8:25 pm-10:24 am

2 stops12h 59m

Florence

Sat 3/21

2:30 pm-7:31 pm

1 stop6h 01m

$494

MinneapolisFlorence

MSP - FLO

MSPFLO

Minneapolis St Paul

Mon 11/24

11:06 am-5:09 pm

1 stop5h 03m

Florence

Sun 11/30

5:15 am-9:19 am

1 stop5h 04m

$524

AppletonFlorence

ATW - FLO

ATWFLO

Appleton Intl

Wed 12/10

5:10 am-10:51 am

2 stops28h 41m

Florence

Sat 12/13

6:31 pm-10:47 pm

1 stop5h 16m

$637

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Wed 11/19

5:00 am-9:54 am

1 stop3h 54m

$229

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 11/17

5:40 pm-10:53 pm

1 stop4h 13m

$229

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 11/10

5:00 am-9:54 am

1 stop3h 54m

$336

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Fri 11/14

10:29 am-5:09 pm

1 stop5h 40m

$336

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Tue 11/11

3:44 pm-10:53 pm

1 stop6h 09m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 12 results
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Best time to book a flight from Wisconsin to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Wisconsin with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wisconsin to Florence

What is the cheapest month to book a flight from Wisconsin to Florence, South Carolina?

Currently, May is the cheapest month in which you can book a flight from Wisconsin to Florence, South Carolina (average of $118). Flying from Wisconsin to Florence, South Carolina in January is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Wisconsin to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Wisconsin?

    Most people fly into Florence (FLO) if they book a flight to Florence from Wisconsin. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Wisconsin to Florence, South Carolina?

    Airlines like American Airlines fly from Wisconsin to Florence, South Carolina in about 6h 16m. The time it takes to get you to your destination can typically vary by up to . Wisconsin and Florence, South Carolina are separated by a distance of 1027 mi.

  • What are the most popular routes from Wisconsin to Florence, South Carolina?

    While some choose either Appleton Intl - Florence or Milwaukee-Mitchell - Florence, Minneapolis St Paul - Florence is the most popular route from Wisconsin to Florence, South Carolina.

  • Can I find deals for flights from Wisconsin to Florence that include hotel bookings?

    Yes. In addition to deals on Wisconsin to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wisconsin to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wisconsin to Florence.

  • Can I find deals for business class flights from Wisconsin to Florence?

    Yes. Cheapflights offers flight deals from Wisconsin to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wisconsin to Florence, South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Wisconsin to Florence, South Carolina (average of $118). Flying from Wisconsin to Florence, South Carolina in January is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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