How long is the flight from Milwaukee to Florence, South Carolina?

A quick flight from Milwaukee to Florence, South Carolina can take about 8h 50m. American Airlines provides one of the quickest options available for as low as $398. The distance from Milwaukee to Florence, South Carolina is about 748 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from MKE to FLO?

When flying from Milwaukee to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Milwaukee-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Milwaukee-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Milwaukee-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Milwaukee-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Milwaukee to Florence that include hotel bookings?

Yes. In addition to deals on Milwaukee to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Milwaukee to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Florence.

Can I find deals for business class flights from Milwaukee to Florence?

Yes. Cheapflights offers flight deals from Milwaukee to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$393+ Cheap Flights from Milwaukee to Florence, SC

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Cheap flight deals from Milwaukee to Florence

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Cheapest flights from Milwaukee to Florence
Explore the most affordable flight options available from Milwaukee to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.

Wed 5/205:06 am

MKE

FLO

2 stops9h 44m

American Airlines

Sun 5/242:35 pm

FLO

MKE

1 stop4h 02m

American Airlines

Deal found 5/4

$393

Find flight deals from Milwaukee to Florence

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$393 (American Airlines)

Provider with most accurate pricing for Milwaukee-Mitchell-Florence flight deals.

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MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Wed 5/20

6:00 am-3:50 pm

2 stops8h 50m

Florence

Sun 5/24

2:35 pm-11:34 pm

2 stops9h 59m

$398

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Deals found on 5/4

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Most accurate provider: When it comes to deals on Milwaukee-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Milwaukee-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Milwaukee-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Milwaukee-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Milwaukee to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Milwaukee with our price prediction graph.

MKE-FLO

Estimated round-trip price

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Related info for your journey

How long is the flight from Milwaukee to Florence, South Carolina?
A quick flight from Milwaukee to Florence, South Carolina can take about 8h 50m. American Airlines provides one of the quickest options available for as low as $398. The distance from Milwaukee to Florence, South Carolina is about 748 mi.
Can I find deals for flights from Milwaukee to Florence that include hotel bookings?
Yes. In addition to deals on Milwaukee to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Milwaukee to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Florence.
Can I find deals for business class flights from Milwaukee to Florence?
Yes. Cheapflights offers flight deals from Milwaukee to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$393+ Cheap flights from Milwaukee to Florence, SC (MKE - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Milwaukee to Florence

Cheapest flights from Milwaukee to FlorenceExplore the most affordable flight options available from Milwaukee to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.

Explore the most affordable flight options available from Milwaukee to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.

Best flights from Milwaukee to FlorenceDiscover carefully curated flight deals from Milwaukee to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.

Discover carefully curated flight deals from Milwaukee to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.

Last-minute flights from Milwaukee to FlorenceDiscover last-minute flight deals from Milwaukee to Florence. Data last updated May 7, 2026 and is based on user searches.

Discover last-minute flight deals from Milwaukee to Florence. Data last updated May 7, 2026 and is based on user searches.

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How long is the flight from Milwaukee to Florence, South Carolina?

Can I find deals for flights from Milwaukee to Florence that include hotel bookings?

How can I find direct flights from Milwaukee to Florence?

Can I find deals for business class flights from Milwaukee to Florence?

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Cheapest flights from Milwaukee to Florence
Explore the most affordable flight options available from Milwaukee to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.

Best flights from Milwaukee to Florence
Discover carefully curated flight deals from Milwaukee to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.

Last-minute flights from Milwaukee to Florence
Discover last-minute flight deals from Milwaukee to Florence. Data last updated May 7, 2026 and is based on user searches.