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South Carolina

$91+ Cheap flights from Milwaukee (MKE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
juil. 8 — juil. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Milwaukee to South Carolina

Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated juillet 3, 2025.

Round-trip from

$193
(Mytrip)

One-way from

$91
(Mytrip)

Popular in

March

Cheapest in

October

Average price

$366
From Milwaukee-Mitchell to South Carolina
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One-way flight from Milwaukee-Mitchell to South Carolina
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Highest demand for flights based on searches. 9% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Milwaukee to South Carolina

Cheapest flights from Milwaukee to South Carolina
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juillet 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 8/166:00 amMKE - MYR
1 stop12h 45mSpirit Airlines
sam. 8/236:31 pmMYR - MKE
1 stop5h 35mSpirit Airlines
Deal found 7/2$193
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/87:49 pmMKE - CLT
1 stop11h 32mAmerican Airlines
sam. 8/912:02 pmCLT - MKE
Nonstop2h 01mAmerican Airlines
Deal found 7/2$215
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/119:45 amMKE - CLT
1 stop6h 32mSpirit Airlines
mer. 8/133:10 pmCLT - MKE
1 stop8h 56mSpirit Airlines
Deal found 7/1$216
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/112:14 pmMKE - CAE
1 stop5h 58mAmerican Airlines
jeu. 8/78:44 pmCAE - MKE
1 stop4h 27mAmerican Airlines
Deal found 7/1$229
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 8/215:15 amMKE - CLT
1 stop7h 05mSouthwest
lun. 8/256:10 pmCLT - MKE
1 stop5h 50mSouthwest
Deal found 7/2$236
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/26:43 pmMKE - SAV
1 stop4h 12mDelta
lun. 10/66:50 pmSAV - MKE
1 stop5h 35mDelta
Deal found 7/3$237
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 9/45:25 amMKE - GSP
1 stop5h 04mDelta
lun. 9/83:20 pmGSP - MKE
1 stop6h 59mDelta
Deal found 7/3$237
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/55:40 amMKE - CHS
1 stop5h 08mDelta
lun. 8/113:18 pmCHS - MKE
1 stop6h 43mDelta
Deal found 7/3$237
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 8/66:00 amMKE - MYR
2 stops8h 23mAmerican Airlines
mar. 8/127:24 pmMYR - MKE
1 stop4h 40mAmerican Airlines
Deal found 7/2$242
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/212:35 pmMKE - SAV
2 stops9h 20mSouthwest
lun. 10/66:45 pmSAV - MKE
1 stop5h 40mSouthwest
Deal found 7/1$242
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 9/411:35 amMKE - GSP
1 stop5h 30mSouthwest
lun. 9/81:50 pmGSP - MKE
2 stops8h 35mSouthwest
Deal found 7/3$242
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/56:27 amMKE - CHS
2 stops7h 26mAmerican Airlines
lun. 8/117:40 pmCHS - MKE
1 stop4h 46mAmerican Airlines
Deal found 7/3$242

Cheapflights Fare Finder

Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juillet 3, 2025.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.

Fly from

Milwaukee

Fly to

South Carolina

Route

Depart

Return

Price

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

sam. 8/16

6:00 am-7:45 pm

1 stop12h 45m

Myrtle Beach Intl

sam. 8/23

6:31 pm-11:06 pm

1 stop5h 35m

$193

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

ven. 8/8

7:49 pm-8:21 am

1 stop11h 32m

Charlotte Douglas

sam. 8/9

12:02 pm-1:03 pm

Nonstop2h 01m

$215

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

lun. 8/11

9:45 am-5:17 pm

1 stop6h 32m

Charlotte Douglas

mer. 8/13

3:10 pm-11:06 pm

1 stop8h 56m

$216

MilwaukeeColumbia

MKE - CAE

MKECAE

Milwaukee-Mitchell

ven. 8/1

12:14 pm-7:12 pm

1 stop5h 58m

Columbia Metropolitan

jeu. 8/7

8:44 pm-12:11 am

1 stop4h 27m

$229

MilwaukeeCharlotte

MKE - CLT

MKECLT

Milwaukee-Mitchell

jeu. 8/21

5:15 am-1:20 pm

1 stop7h 05m

Charlotte Douglas

lun. 8/25

6:10 pm-11:00 pm

1 stop5h 50m

$236

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

jeu. 8/14

6:36 pm-11:59 pm

1 stop4h 23m

Savannah/Hilton Head

lun. 8/18

5:05 pm-8:46 pm

1 stop4h 41m

$237

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

jeu. 9/4

5:25 am-11:29 am

1 stop5h 04m

Greenville

lun. 9/8

3:20 pm-9:19 pm

1 stop6h 59m

$237

MilwaukeeCharleston

MKE - CHS

MKECHS

Milwaukee-Mitchell

mar. 8/5

5:40 am-11:48 am

1 stop5h 08m

Charleston

lun. 8/11

3:18 pm-9:01 pm

1 stop6h 43m

$237

MilwaukeeSavannah

MKE - SAV

MKESAV

Milwaukee-Mitchell

jeu. 9/25

11:35 am-9:20 pm

2 stops8h 45m

Savannah/Hilton Head

lun. 9/29

7:00 pm-11:00 pm

1 stop5h 00m

$242

MilwaukeeMyrtle Beach

MKE - MYR

MKEMYR

Milwaukee-Mitchell

mer. 8/6

6:00 am-3:23 pm

2 stops8h 23m

Myrtle Beach Intl

mar. 8/12

7:24 pm-11:04 pm

1 stop4h 40m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Showing 1-10 of 60 results
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Best time to book a flight from Milwaukee to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to South Carolina

What is the cheapest month to book a flight from Milwaukee to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MKE to SC?

Find hourly flight availability from Milwaukee to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated juillet 3, 2025.

When flying from Milwaukee to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated juillet 3, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,270 reviews

Comfort

8.0

Entertainment

7.6

Boarding

8.2

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,270 reviews
Southwest
8.0
Very good
4,270 reviews

Comfort

8.0

Entertainment

7.6

Boarding

8.2

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,970 reviews
Southwest
8.0
Very good
4,270 reviews

Comfort

8.0

Entertainment

7.6

Boarding

8.2

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,845 reviews
Southwest
8.0
Very good
4,270 reviews

Comfort

8.0

Entertainment

7.6

Boarding

8.2

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,270 reviews

Comfort

8.0

Entertainment

7.6

Boarding

8.2

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Sun Country Air
6.9
Okay
339 reviews
Southwest
8.0
Very good
4,270 reviews

Comfort

8.0

Entertainment

7.6

Boarding

8.2

Crew

8.6

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Milwaukee to South Carolina?

    Milwaukee-Mitchell (MKE), located 6.4 mi from the city center, is the airport you fly out of when you book flights from Milwaukee to South Carolina.

  • What are the cheapest airlines to fly from Milwaukee to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $91. Users have also found prices from $119 and $138 on American Airlines and Sun Country Air, respectively.

  • What are the most popular routes from Milwaukee to South Carolina?

    While some choose either Milwaukee-Mitchell - Savannah/Hilton Head or Milwaukee-Mitchell - Greenville, Milwaukee-Mitchell - Charlotte Douglas is the most popular route from Milwaukee to South Carolina.

  • Can I find deals for flights from Milwaukee to South Carolina that include hotel bookings?

    Yes. In addition to deals on Milwaukee to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to South Carolina.

  • Can I find deals for business class flights from Milwaukee to South Carolina?

    Yes. Cheapflights offers flight deals from Milwaukee to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $217). Flying from Milwaukee to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Milwaukee to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Milwaukee to South Carolina

Discover the top 5 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juillet 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$141Average$239FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$213Average$368FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$375FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$220Average$374FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$256Average$401FlexibilityNo cancel feeOn-time63%

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