$111+ Cheap flights from Milwaukee (MKE) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Sep 28 — Oct 51
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Milwaukee to South Carolina
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Cheapest flights from Milwaukee to South CarolinaExplore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
This Frontier deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:10 am -
1 stop7h 11m
Sat 9/269:40 pm -
1 stop12h 42m
Deal found 8/27![Frontier logo]()
$222
This CheapOair deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:15 am -
1 stop5h 50m
Wed 10/289:32 am -
1 stop24h 44m
Deal found 8/25![Frontier logo]()
$246
This CheapOair deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:15 am -
1 stop21h 22m
Wed 10/289:32 am -
1 stop24h 44m
Deal found 8/27![Frontier logo]()
$257
This CheapOair deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:15 am -
1 stop21h 22m
Mon 10/266:00 am -
1 stop28h 16m
Deal found 8/27![Frontier logo]()
$259
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:52 pm -
1 stop4h 25m
Wed 10/76:00 am -
1 stop5h 48m
Deal found 8/25![United Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:10 pm -
1 stop12h 17m
Thu 10/159:08 am -
Nonstop2h 06m
Deal found 8/25![American Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 pm -
2 stops4h 45m
Sat 10/248:00 am -
1 stop5h 20m
Deal found 8/25![Southwest logo]()
$264
This CheapOair deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:15 am -
1 stop21h 22m
Sat 10/179:42 pm -
1 stop12h 38m
Deal found 8/29![Frontier logo]()
$268
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops5h 25m
Wed 9/308:15 am -
2 stops9h 05m
Deal found 8/26![Southwest logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:53 pm -
1 stop4h 12m
Sat 10/104:53 pm -
1 stop6h 49m
Deal found 8/27![American Airlines logo]()
$270
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop6h 44m
Sat 10/318:00 am -
1 stop4h 34m
Deal found 8/27![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:16 am -
1 stop4h 14m
Wed 10/144:13 pm -
1 stop6h 11m
Deal found 8/25![Delta logo]()
$271
Best flights from Milwaukee to South CarolinaDiscover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
Discover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop6h 44m
Sat 10/318:00 am -
1 stop4h 34m
Deal found 8/24![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:30 am -
1 stop4h 40m
Tue 10/201:16 pm -
2 stops10h 43m
Deal found 8/24![United Airlines logo]()
$296
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:45 am -
1 stop4h 25m
Wed 9/161:30 pm -
2 stops8h 05m
Deal found 8/24![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:01 pm -
1 stop9h 02m
Fri 11/277:00 am -
1 stop4h 04m
Deal found 8/26![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:16 am -
1 stop3h 52m
Tue 11/35:11 pm -
1 stop4h 11m
Deal found 8/28![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
2 stops7h 21m
Tue 9/1510:22 am -
2 stops8h 08m
Deal found 8/26![United Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:00 am -
1 stop4h 10m
Mon 10/56:40 am -
1 stop5h 05m
Deal found 8/24![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:05 pm -
1 stop4h 10m
Sat 10/175:55 pm -
1 stop4h 35m
Deal found 8/27![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:49 pm -
1 stop4h 46m
Tue 10/205:30 am -
1 stop6h 59m
Deal found 8/26![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:51 pm -
1 stop4h 43m
Tue 10/138:53 am -
1 stop7h 18m
Deal found 8/24![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:14 pm -
2 stops17h 07m
Tue 10/62:13 pm -
1 stop7h 14m
Deal found 8/27![American Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:20 am -
2 stops5h 30m
Thu 11/124:30 pm -
2 stops7h 35m
Deal found 8/25![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:37 pm -
1 stop4h 18m
Mon 9/285:30 am -
1 stop4h 36m
Deal found 8/27![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
1 stop3h 51m
Wed 11/1811:58 am -
1 stop7h 08m
Deal found 8/25![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:04 am -
2 stops10h 45m
Tue 11/175:45 am -
2 stops9h 37m
Deal found 8/26![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:40 am -
2 stops10h 25m
Thu 10/11:35 pm -
2 stops10h 30m
Deal found 8/24![Southwest logo]()
$333
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:37 pm -
1 stop4h 18m
Sat 10/108:20 am -
1 stop6h 34m
Deal found 8/24![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:00 am -
2 stops8h 16m
Mon 9/284:23 pm -
1 stop6h 02m
Deal found 8/27![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:20 am -
2 stops10h 10m
Mon 10/198:40 pm -
1 stop4h 35m
Deal found 8/24![Southwest logo]()
$333
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:21 am -
1 stop4h 48m
Mon 9/712:46 pm -
2 stops8h 13m
Deal found 8/29![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:00 am -
2 stops8h 16m
Sat 10/103:38 pm -
1 stop4h 32m
Deal found 8/24![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:16 am -
1 stop4h 14m
Wed 10/284:13 pm -
1 stop6h 11m
Deal found 8/28![Delta logo]()
$346
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:20 am -
2 stops8h 40m
Thu 11/51:40 pm -
2 stops9h 10m
Deal found 8/27![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:00 am -
2 stops8h 13m
Wed 9/234:58 pm -
1 stop5h 12m
Deal found 8/26![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:49 pm -
1 stop5h 39m
Wed 9/236:58 pm -
1 stop5h 50m
Deal found 8/27![Delta logo]()
$347
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:06 am -
2 stops9h 39m
Fri 10/22:15 pm -
1 stop6h 18m
Deal found 8/28![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:00 am -
1 stop4h 10m
Sat 9/1211:55 am -
2 stops8h 10m
Deal found 8/28![Southwest logo]()
$342
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:42 am -
1 stop5h 15m
Sat 10/1710:29 am -
1 stop5h 42m
Deal found 8/26![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:16 pm -
1 stop3h 52m
Fri 11/135:20 am -
1 stop7h 17m
Deal found 8/27![Delta logo]()
$352
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 am -
2 stops11h 38m
Sat 10/316:30 am -
1 stop4h 44m
Deal found 8/24![American Airlines logo]()
$443
Last-minute flights from Milwaukee to South CarolinaDiscover last-minute flight deals from Milwaukee to South Carolina. Data last updated August 29, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to South Carolina. Data last updated August 29, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
1 stop4h 09m
Sun 9/65:49 pm -
1 stop7h 04m
Deal found 8/29![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:30 am -
2 stops9h 37m
Sun 9/610:23 am -
1 stop6h 47m
Deal found 8/29![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:59 pm -
1 stop4h 50m
Fri 9/115:45 pm -
1 stop4h 45m
Deal found 8/26![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:21 am -
1 stop6h 24m
Tue 9/87:42 am -
1 stop4h 15m
Deal found 8/29![American Airlines logo]()
$314
This CheapOair deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/812:10 pm -
1 stop26h 06m
Sat 9/129:40 pm -
1 stop12h 42m
Deal found 8/27![Frontier logo]()
$290
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 am -
1 stop6h 44m
Sun 9/137:30 am -
1 stop5h 10m
Deal found 8/25![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:00 am -
2 stops8h 21m
Tue 9/156:25 am -
1 stop4h 35m
Deal found 8/26![United Airlines logo]()
$315
This Frontier deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:10 am -
1 stop7h 11m
Sat 9/269:40 pm -
1 stop12h 42m
Deal found 8/27![Frontier logo]()
$222
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:20 pm -
1 stop5h 57m
Wed 9/306:53 pm -
1 stop5h 44m
Deal found 8/26![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops5h 25m
Wed 9/308:15 am -
2 stops9h 05m
Deal found 8/26![Southwest logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:03 am -
1 stop5h 00m
Fri 9/256:23 pm -
1 stop4h 31m
Deal found 8/25![American Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:03 am -
1 stop7h 07m
Tue 10/610:55 am -
1 stop6h 45m
Deal found 8/25![American Airlines logo]()
$314
One-way flights from Milwaukee to South CarolinaSearch for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
Search for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
This Frontier deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:10 am -
1 stop7h 11m
Deal found 8/26![Frontier logo]()
$111
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:10 am -
1 stop21h 25m
Deal found 8/28![Frontier logo]()
$117
This Frontier deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:15 am -
1 stop5h 50m
Deal found 8/26![Frontier logo]()
$118
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:18 pm -
1 stop6h 00m
Deal found 8/25![United Airlines logo]()
$130
This Cheapflightsfares deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/812:10 pm -
1 stop26h 06m
Deal found 8/25![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:15 am -
1 stop21h 22m
Deal found 8/28![Frontier logo]()
$139
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:49 pm -
1 stop5h 06m
Deal found 8/25![Delta logo]()
$139
This CheapOair deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:15 am -
1 stop21h 22m
Deal found 8/27![Frontier logo]()
$142
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:40 am -
1 stop6h 12m
Deal found 8/25![United Airlines logo]()
$149
This Priceline deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:10 am -
1 stop7h 11m
Deal found 8/25![Frontier logo]()
$150
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:05 am -
1 stop7h 58m
Deal found 8/28![United Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:15 am -
1 stop21h 22m
Deal found 8/25![Frontier logo]()
$157
Find flight deals from Milwaukee to South Carolina
Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated August 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $222 (Frontier) |
One-way from | $111 (Frontier) |
Popular in | March |
Cheapest in | January |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeColumbia
MKE Milwaukee-Mitchell - CAE Columbia Metropolitan
MKECAE
Milwaukee-Mitchell
Wed 10/28
5:30 am-1:14 pm
1 stop6h 44m
Columbia Metropolitan
Sat 10/31
8:00 am-11:34 am
1 stop4h 34m
$271
Quickest round-trip
MilwaukeeColumbia
MKE Milwaukee-Mitchell - CAE Columbia Metropolitan
MKECAE
Milwaukee-Mitchell
Thu 10/29
10:16 am-3:08 pm
1 stop3h 52m
Columbia Metropolitan
Tue 11/3
5:11 pm-8:22 pm
1 stop4h 11m
$295
MilwaukeeHilton Head Island
MKE Milwaukee-Mitchell - HHH Hilton Head Island
MKEHHH
Milwaukee-Mitchell
Sat 10/17
8:30 am-2:10 pm
1 stop4h 40m
Hilton Head Island
Tue 10/20
1:16 pm-10:59 pm
2 stops10h 43m
$296
MilwaukeeColumbia
MKE Milwaukee-Mitchell - CAE Columbia Metropolitan
MKECAE
Milwaukee-Mitchell
Fri 9/11
6:00 am-2:21 pm
2 stops7h 21m
Columbia Metropolitan
Tue 9/15
10:22 am-5:30 pm
2 stops8h 08m
$320
MilwaukeeCharlotte
MKE Milwaukee-Mitchell - CLT Charlotte Douglas
MKECLT
Milwaukee-Mitchell
Mon 9/14
5:45 am-11:10 am
1 stop4h 25m
Charlotte Douglas
Wed 9/16
1:30 pm-8:35 pm
2 stops8h 05m
$322
MilwaukeeMyrtle Beach
MKE Milwaukee-Mitchell - MYR Myrtle Beach Intl
MKEMYR
Milwaukee-Mitchell
Mon 9/28
8:00 am-1:10 pm
1 stop4h 10m
Myrtle Beach Intl
Mon 10/5
6:40 am-10:45 am
1 stop5h 05m
$325
MilwaukeeMyrtle Beach
MKE Milwaukee-Mitchell - MYR Myrtle Beach Intl
MKEMYR
Milwaukee-Mitchell
Sat 10/10
1:05 pm-6:15 pm
1 stop4h 10m
Myrtle Beach Intl
Sat 10/17
5:55 pm-9:30 pm
1 stop4h 35m
$325
MilwaukeeCharlotte
MKE Milwaukee-Mitchell - CLT Charlotte Douglas
MKECLT
Milwaukee-Mitchell
Tue 11/10
6:20 am-12:50 pm
2 stops5h 30m
Charlotte Douglas
Thu 11/12
4:30 pm-11:05 pm
2 stops7h 35m
$327
MilwaukeeCharlotte
MKE Milwaukee-Mitchell - CLT Charlotte Douglas
MKECLT
Milwaukee-Mitchell
Tue 9/29
7:40 am-7:05 pm
2 stops10h 25m
Charlotte Douglas
Thu 10/1
1:35 pm-11:05 pm
2 stops10h 30m
$333
MilwaukeeGreenville
MKE Milwaukee-Mitchell - GSP Greenville
MKEGSP
Milwaukee-Mitchell
Fri 10/16
10:20 am-9:30 pm
2 stops10h 10m
Greenville
Mon 10/19
8:40 pm-12:15 am
1 stop4h 35m
$333
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
MKE-GSP
MKE-CLT
MKE-CHS
MKE-MYR
MKE-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to South Carolina
MKE-USSC
MKE-GSP
MKE-CLT
MKE-CHS
MKE-MYR
What is the cheapest month to book a flight from Milwaukee to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $349). Flying from Milwaukee to South Carolina in June is currently the most expensive (average of $425). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Milwaukee to South Carolina?
Airfare is below average for this route at the moment.
Milwaukee to South Carolina flights typically cost between $380 and $528 in October.The cheapest round-trip price found within the last 5 days was $339 on Delta (Oct 6-Oct 14).
How far ahead should I book a flight from Milwaukee to South Carolina?
The best time to book flights from Milwaukee to South Carolina is 8 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 29, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Milwaukee and South Carolina flights
Browse other Milwaukee and South Carolina flight options. Last updated on August 29, 2026.
Popular flight searches
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Milwaukee to South Carolina flights
Consider these flights traveling from Milwaukee to South Carolina.
Top 4 airlines flying from Milwaukee to South Carolina
Discover the top 4 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$381 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$290 | Average$445 | FlexibilityNo cancel fee | On-time63% |