$122+ Cheap flights from Milwaukee (MKE) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Aug 13 — Aug 201
Round-trip
1 adult, Economy
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Find cheap flights from Milwaukee to South Carolina with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Milwaukee to South CarolinaExplore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:34 am
MKE
- MYR
1 stop4h 13m
Delta
Mon 8/177:02 pm
MYR
- MKE
1 stop5h 51m
Delta
Deal found 7/9![Delta logo]()
$243
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:05 pm
MKE
- MYR
1 stop4h 15m
Southwest
Thu 8/201:55 pm
MYR
- MKE
2 stops8h 30m
Southwest
Deal found 7/9![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:23 pm
MKE
- CHS
1 stop4h 20m
Delta
Tue 10/134:20 pm
CHS
- MKE
1 stop5h 42m
Delta
Deal found 7/9![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:20 am
MKE
- MYR
2 stops6h 45m
Southwest
Fri 8/283:20 pm
MYR
- MKE
2 stops7h 05m
Southwest
Deal found 7/9![Southwest logo]()
$253
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
MKE
- GSP
1 stop4h 00m
American Airlines
Sat 8/156:45 am
GSP
- MKE
1 stop5h 17m
American Airlines
Deal found 7/11![American Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:20 am
MKE
- MYR
2 stops9h 50m
Southwest
Wed 9/235:05 pm
MYR
- MKE
1 stop4h 50m
Southwest
Deal found 7/10![Southwest logo]()
$254
This Frontier deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/59:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/9![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 am
MKE
- MYR
1 stop7h 03m
Delta
Sat 9/193:56 pm
MYR
- MKE
1 stop6h 34m
Delta
Deal found 7/9![Delta logo]()
$259
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:49 pm
MKE
- GSP
1 stop6h 01m
American Airlines
Sat 8/295:19 pm
GSP
- MKE
1 stop6h 40m
American Airlines
Deal found 7/13![American Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:47 pm
MKE
- CHS
1 stop4h 12m
Delta
Tue 10/271:01 pm
CHS
- MKE
1 stop4h 00m
Delta
Deal found 7/10![Delta logo]()
$259
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:45 am
MKE
- CAE
1 stop6h 35m
American Airlines
Sat 10/318:30 pm
CAE
- MKE
1 stop4h 27m
American Airlines
Deal found 7/9![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:15 am
MKE
- HHH
1 stop4h 11m
Delta
Tue 10/274:00 pm
HHH
- MKE
1 stop5h 56m
Delta
Deal found 7/10![Delta logo]()
$261
Best flights from Milwaukee to South CarolinaDiscover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
Discover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:49 pm
MKE
- MYR
1 stop6h 49m
American Airlines
Mon 8/175:15 pm
MYR
- MKE
1 stop6h 44m
American Airlines
Deal found 7/10![American Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:11 am
MKE
- MYR
1 stop6h 53m
Delta
Wed 9/236:00 am
MYR
- MKE
1 stop4h 06m
Delta
Deal found 7/10![Delta logo]()
$243
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:05 pm
MKE
- MYR
1 stop4h 15m
Southwest
Thu 8/201:55 pm
MYR
- MKE
2 stops8h 30m
Southwest
Deal found 7/9![Southwest logo]()
$248
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:00 am
MKE
- CAE
1 stop4h 28m
United Airlines
Sat 8/156:25 am
CAE
- MKE
1 stop4h 35m
United Airlines
Deal found 7/9![United Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:34 am
MKE
- MYR
1 stop4h 13m
Delta
Mon 8/177:02 pm
MYR
- MKE
1 stop5h 51m
Delta
Deal found 7/9![Delta logo]()
$243
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
MKE
- GSP
1 stop4h 00m
American Airlines
Sat 8/156:45 am
GSP
- MKE
1 stop5h 17m
American Airlines
Deal found 7/11![American Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:20 am
MKE
- MYR
2 stops9h 50m
Southwest
Wed 9/235:05 pm
MYR
- MKE
1 stop4h 50m
Southwest
Deal found 7/10![Southwest logo]()
$254
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 am
MKE
- MYR
1 stop7h 03m
Delta
Sat 9/193:56 pm
MYR
- MKE
1 stop6h 34m
Delta
Deal found 7/10![Delta logo]()
$259
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:30 am
MKE
- CAE
2 stops6h 42m
United Airlines
Sat 11/76:25 am
CAE
- MKE
1 stop4h 36m
United Airlines
Deal found 7/9![United Airlines logo]()
$290
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:50 am
MKE
- GSP
1 stop10h 35m
Southwest
Thu 8/67:00 am
GSP
- MKE
1 stop4h 10m
Southwest
Deal found 7/9![Southwest logo]()
$270
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:24 am
MKE
- HHH
1 stop4h 08m
Delta
Wed 9/3012:15 pm
HHH
- MKE
2 stops8h 50m
Delta
Deal found 7/10![Delta logo]()
$266
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:30 am
MKE
- SAV
2 stops8h 30m
Southwest
Thu 12/36:40 am
SAV
- MKE
1 stop4h 05m
Southwest
Deal found 7/10![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:00 am
MKE
- HHH
1 stop7h 17m
American Airlines
Thu 8/135:16 pm
HHH
- MKE
1 stop5h 31m
American Airlines
Deal found 7/9![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:29 pm
MKE
- SAV
1 stop6h 28m
Delta
Thu 12/35:35 pm
SAV
- MKE
1 stop4h 13m
Delta
Deal found 7/10![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:30 am
MKE
- SAV
2 stops8h 05m
United Airlines
Wed 9/166:10 am
SAV
- MKE
1 stop4h 50m
United Airlines
Deal found 7/11![United Airlines logo]()
$326
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:30 pm
MKE
- MYR
1 stop6h 10m
Southwest
Mon 8/242:00 pm
MYR
- MKE
1 stop7h 15m
Southwest
Deal found 7/13![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:47 pm
MKE
- SAV
1 stop4h 10m
Delta
Mon 10/196:45 am
SAV
- MKE
1 stop5h 44m
Delta
Deal found 7/10![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:50 pm
MKE
- GSP
1 stop5h 21m
United Airlines
Wed 12/98:40 am
GSP
- MKE
1 stop6h 03m
United Airlines
Deal found 7/10![United Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:14 am
MKE
- HHH
1 stop7h 05m
American Airlines
Tue 11/172:51 pm
HHH
- MKE
1 stop4h 10m
American Airlines
Deal found 7/13![American Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:45 am
MKE
- SAV
1 stop4h 33m
Delta
Mon 11/165:35 pm
SAV
- MKE
1 stop7h 14m
Delta
Deal found 7/9![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:45 am
MKE
- GSP
2 stops9h 20m
Southwest
Thu 8/134:40 pm
GSP
- MKE
1 stop5h 00m
Southwest
Deal found 7/9![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:30 am
MKE
- CAE
1 stop6h 30m
United Airlines
Sat 10/316:25 am
CAE
- MKE
1 stop4h 36m
United Airlines
Deal found 7/11![United Airlines logo]()
$341
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:30 am
MKE
- HHH
1 stop4h 33m
United Airlines
Tue 9/12:58 pm
HHH
- MKE
1 stop7h 02m
United Airlines
Deal found 7/8![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:15 am
MKE
- HHH
1 stop4h 11m
Delta
Tue 10/274:00 pm
HHH
- MKE
1 stop5h 56m
Delta
Deal found 7/10![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:00 pm
MKE
- CLT
1 stop3h 45m
Southwest
Mon 10/59:00 pm
CLT
- MKE
1 stop4h 15m
Southwest
Deal found 7/12![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:00 am
MKE
- CAE
1 stop4h 28m
United Airlines
Thu 8/136:25 am
CAE
- MKE
1 stop7h 13m
United Airlines
Deal found 7/13![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:15 am
MKE
- HHH
1 stop4h 11m
Delta
Tue 10/1312:15 pm
HHH
- MKE
2 stops10h 34m
Delta
Deal found 7/10![Delta logo]()
$290
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:40 am
MKE
- CLT
1 stop4h 15m
Southwest
Wed 8/266:35 pm
CLT
- MKE
1 stop3h 50m
Southwest
Deal found 7/13![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:27 pm
MKE
- AGS
1 stop4h 39m
American Airlines
Fri 1/16:16 pm
AGS
- MKE
1 stop6h 42m
American Airlines
Deal found 7/12![American Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:00 am
MKE
- CAE
2 stops8h 21m
United Airlines
Sat 9/510:22 am
CAE
- MKE
2 stops9h 33m
United Airlines
Deal found 7/10![United Airlines logo]()
$351
Last-minute flights from Milwaukee to South CarolinaDiscover last-minute flight deals from Milwaukee to South Carolina. Data last updated July 14, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to South Carolina. Data last updated July 14, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 8/59:43 pm
CLT
- MKE
1 stop11h 15m
Frontier
Deal found 7/9![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:03 am
MKE
- CHS
1 stop5h 49m
Delta
Sat 8/156:00 am
CHS
- MKE
1 stop4h 12m
Delta
Deal found 7/9![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 am
MKE
- GSP
1 stop4h 00m
American Airlines
Sat 8/156:45 am
GSP
- MKE
1 stop5h 17m
American Airlines
Deal found 7/11![American Airlines logo]()
$253
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:00 am
MKE
- CAE
1 stop4h 28m
United Airlines
Sat 8/156:25 am
CAE
- MKE
1 stop4h 35m
United Airlines
Deal found 7/9![United Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:34 am
MKE
- MYR
1 stop4h 13m
Delta
Mon 8/177:02 pm
MYR
- MKE
1 stop5h 51m
Delta
Deal found 7/9![Delta logo]()
$243
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:05 pm
MKE
- MYR
1 stop4h 15m
Southwest
Thu 8/201:55 pm
MYR
- MKE
2 stops8h 30m
Southwest
Deal found 7/9![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:22 am
MKE
- SAV
1 stop4h 31m
Delta
Thu 8/2711:22 am
SAV
- MKE
1 stop5h 40m
Delta
Deal found 7/9![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:20 am
MKE
- MYR
2 stops6h 45m
Southwest
Fri 8/283:20 pm
MYR
- MKE
2 stops7h 05m
Southwest
Deal found 7/9![Southwest logo]()
$253
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:49 pm
MKE
- GSP
1 stop6h 01m
American Airlines
Sat 8/295:19 pm
GSP
- MKE
1 stop6h 40m
American Airlines
Deal found 7/13![American Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:19 am
MKE
- GSP
2 stops7h 46m
United Airlines
Sat 8/295:43 pm
GSP
- MKE
1 stop4h 17m
United Airlines
Deal found 7/13![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 am
MKE
- HHH
1 stop6h 15m
American Airlines
Wed 9/302:15 pm
HHH
- MKE
1 stop6h 18m
American Airlines
Deal found 7/10![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:24 am
MKE
- HHH
1 stop4h 08m
Delta
Wed 9/3012:15 pm
HHH
- MKE
2 stops8h 50m
Delta
Deal found 7/10![Delta logo]()
$266
One-way flights from Milwaukee to South CarolinaSearch for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
Search for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:49 pm
MKE
- MYR
1 stop6h 49m
American Airlines
Deal found 7/10![American Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 pm
MKE
- CLT
1 stop19h 28m
Frontier
Deal found 7/12![Frontier logo]()
$125
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:51 pm
MKE
- CHS
1 stop5h 00m
Delta
Deal found 7/9![Delta logo]()
$125
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:45 am
MKE
- MYR
2 stops6h 25m
Southwest
Deal found 7/10![Southwest logo]()
$127
This Frontier deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Deal found 7/10![Frontier logo]()
$129
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:30 am
MKE
- CHS
2 stops8h 15m
Southwest
Deal found 7/10![Southwest logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:10 pm
MKE
- CLT
1 stop18h 51m
Frontier
Deal found 7/11![Frontier logo]()
$133
This Frontier deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Deal found 7/10![Frontier logo]()
$134
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:47 pm
MKE
- SAV
1 stop4h 10m
Delta
Deal found 7/9![Delta logo]()
$134
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:01 pm
MKE
- CHS
1 stop4h 43m
Delta
Deal found 7/10![Delta logo]()
$134
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:30 am
MKE
- CLT
1 stop10h 50m
Southwest
Deal found 7/10![Southwest logo]()
$135
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
MKE
- SAV
2 stops9h 00m
Southwest
Deal found 7/10![Southwest logo]()
$139
Find flight deals from Milwaukee to South Carolina
Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated July 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (Delta) |
One-way from | $122 (American Airlines) |
Popular in | February |
Cheapest in | January |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Thu 8/13
2:49 pm-10:38 pm
1 stop6h 49m
Myrtle Beach Intl
Mon 8/17
5:15 pm-10:59 pm
1 stop6h 44m
$243
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Wed 9/16
10:11 am-6:04 pm
1 stop6h 53m
Myrtle Beach Intl
Wed 9/23
6:00 am-9:06 am
1 stop4h 06m
$243
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Thu 8/13
5:34 am-10:47 am
1 stop4h 13m
Myrtle Beach Intl
Mon 8/17
7:02 pm-11:53 pm
1 stop5h 51m
$243
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Wed 8/19
2:05 pm-7:20 pm
1 stop4h 15m
Myrtle Beach Intl
Thu 8/20
1:55 pm-9:25 pm
2 stops8h 30m
$248
MilwaukeeGreenville
MKE - GSP
MKEGSP
Milwaukee-Mitchell
Sat 8/8
6:00 am-11:00 am
1 stop4h 00m
Greenville
Sat 8/15
6:45 am-11:02 am
1 stop5h 17m
$253
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Wed 9/16
8:20 am-7:10 pm
2 stops9h 50m
Myrtle Beach Intl
Wed 9/23
5:05 pm-8:55 pm
1 stop4h 50m
$254
MilwaukeeMyrtle Beach
MKE - MYR
MKEMYR
Milwaukee-Mitchell
Tue 9/15
5:30 am-1:33 pm
1 stop7h 03m
Myrtle Beach Intl
Sat 9/19
3:56 pm-9:30 pm
1 stop6h 34m
$259
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Sat 8/8
5:00 am-10:28 am
1 stop4h 28m
Columbia Metropolitan
Sat 8/15
6:25 am-10:00 am
1 stop4h 35m
$261
MilwaukeeHilton Head Island
MKE - HHH
MKEHHH
Milwaukee-Mitchell
Sat 8/29
10:24 am-3:32 pm
1 stop4h 08m
Hilton Head Island
Wed 9/30
12:15 pm-8:05 pm
2 stops8h 50m
$266
MilwaukeeSavannah
MKE - SAV
MKESAV
Milwaukee-Mitchell
Fri 11/6
4:29 pm-11:57 pm
1 stop6h 28m
Savannah/Hilton Head
Thu 12/3
5:35 pm-8:48 pm
1 stop4h 13m
$267
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
MKE-MYR
MKE-SAV
MKE-CHS
MKE-CLT
MKE-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to South Carolina
MKE-USSC
MKE-MYR
MKE-SAV
MKE-CHS
MKE-CLT
What is the cheapest month to book a flight from Milwaukee to South Carolina?
Currently, March is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $100). Flying from Milwaukee to South Carolina in April is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Milwaukee to South Carolina?
How far ahead should I book a flight from Milwaukee to South Carolina?
The best time to book flights from Milwaukee to South Carolina is 6 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 14, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Milwaukee to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Milwaukee to South Carolina by cabin class
Find flights from Milwaukee to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Milwaukee and South Carolina flights
Browse other Milwaukee and South Carolina flight options. Last updated on July 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Milwaukee to South Carolina flights
Consider these flights traveling from Milwaukee to South Carolina.
Top 4 airlines flying from Milwaukee to South Carolina
Discover the top 4 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$290 | Average$424 | FlexibilityNo cancel fee | On-time63% |