$129+ Cheap flights from Milwaukee (MKE) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — CHS
Jun 30 — Jul 71
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Milwaukee to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Milwaukee to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Milwaukee to South CarolinaExplore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
Explore the most affordable flight options available from Milwaukee to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:38 am
MKE
- SAV
1 stop6h 41m
Delta
Wed 9/238:00 am
SAV
- MKE
1 stop4h 53m
Delta
Deal found 5/29![Delta logo]()
$253
This Frontier deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Mon 8/178:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/29![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:45 am
MKE
- AGS
1 stop6h 31m
Delta
Sat 10/3111:35 am
AGS
- MKE
1 stop4h 29m
Delta
Deal found 5/30![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:24 am
MKE
- CAE
1 stop5h 41m
American Airlines
Sat 10/315:18 pm
CAE
- MKE
1 stop5h 00m
American Airlines
Deal found 5/28![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:01 am
MKE
- HHH
1 stop6h 15m
American Airlines
Tue 7/2811:47 am
HHH
- MKE
1 stop6h 50m
American Airlines
Deal found 5/30![American Airlines logo]()
$261
This Frontier deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Mon 8/178:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/28![Frontier logo]()
$263
This Frontier deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:43 am
MKE
- CLT
1 stop7h 15m
Frontier
Mon 7/208:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/29![Frontier logo]()
$268
This Booking.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Wed 8/191:12 pm
CLT
- MKE
1 stop19h 46m
Frontier
Deal found 5/29![Frontier logo]()
$270
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:03 pm
MKE
- CAE
1 stop4h 47m
Delta
Tue 8/1810:04 am
CAE
- MKE
1 stop4h 49m
Delta
Deal found 5/28![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:11 am
MKE
- HHH
1 stop4h 18m
Delta
Tue 7/2812:11 pm
HHH
- MKE
2 stops11h 19m
Delta
Deal found 5/27![Delta logo]()
$276
This Booking.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Mon 6/297:58 pm
CLT
- MKE
1 stop13h 00m
Frontier
Deal found 5/30![Frontier logo]()
$281
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:43 am
MKE
- CLT
1 stop6h 55m
Frontier
Wed 7/228:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/30![Frontier logo]()
$284
Best flights from Milwaukee to South CarolinaDiscover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
Discover carefully curated flight deals from Milwaukee to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:45 am
MKE
- AGS
1 stop6h 31m
Delta
Sat 10/3111:35 am
AGS
- MKE
1 stop4h 29m
Delta
Deal found 5/30![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:24 am
MKE
- AGS
1 stop5h 51m
American Airlines
Sat 10/316:18 pm
AGS
- MKE
1 stop6h 53m
American Airlines
Deal found 5/30![American Airlines logo]()
$261
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 am
MKE
- SAV
2 stops8h 16m
United Airlines
Wed 9/306:20 am
SAV
- MKE
1 stop5h 33m
United Airlines
Deal found 5/30![United Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:30 pm
MKE
- GSP
1 stop5h 20m
Southwest
Tue 7/77:40 pm
GSP
- MKE
1 stop4h 35m
Southwest
Deal found 5/28![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:20 pm
MKE
- AGS
1 stop5h 27m
Delta
Sat 11/287:45 pm
AGS
- MKE
1 stop5h 04m
Delta
Deal found 5/30![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:30 pm
MKE
- CAE
1 stop5h 02m
American Airlines
Wed 11/185:18 pm
CAE
- MKE
1 stop6h 47m
American Airlines
Deal found 5/31![American Airlines logo]()
$261
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:00 am
MKE
- SAV
1 stop4h 40m
United Airlines
Sat 8/299:50 am
SAV
- MKE
2 stops10h 05m
United Airlines
Deal found 5/30![United Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:11 am
MKE
- HHH
1 stop4h 18m
Delta
Tue 7/2812:11 pm
HHH
- MKE
2 stops11h 19m
Delta
Deal found 5/27![Delta logo]()
$276
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:00 am
MKE
- CAE
1 stop5h 52m
American Airlines
Sat 7/116:03 pm
CAE
- MKE
1 stop6h 51m
American Airlines
Deal found 5/27![American Airlines logo]()
$292
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:20 am
MKE
- CAE
1 stop6h 26m
United Airlines
Sat 7/1110:31 am
CAE
- MKE
2 stops9h 55m
United Airlines
Deal found 5/27![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:30 am
MKE
- SAV
2 stops8h 05m
Southwest
Sun 9/207:15 am
SAV
- MKE
1 stop5h 55m
Southwest
Deal found 5/29![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:40 pm
MKE
- CAE
1 stop4h 06m
Delta
Tue 8/1811:55 am
CAE
- MKE
1 stop5h 18m
Delta
Deal found 5/29![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:20 am
MKE
- GSP
1 stop5h 12m
United Airlines
Wed 9/26:30 am
GSP
- MKE
1 stop7h 08m
United Airlines
Deal found 5/29![United Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:03 am
MKE
- HHH
1 stop4h 42m
American Airlines
Tue 10/66:13 pm
HHH
- MKE
1 stop6h 58m
American Airlines
Deal found 5/27![American Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:51 pm
MKE
- MYR
1 stop4h 16m
Delta
Mon 8/176:00 am
MYR
- MKE
1 stop4h 16m
Delta
Deal found 5/31![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:45 am
MKE
- MYR
2 stops6h 25m
Southwest
Sun 9/206:50 pm
MYR
- MKE
1 stop4h 40m
Southwest
Deal found 5/29![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:21 pm
MKE
- FLO
1 stop4h 12m
American Airlines
Tue 7/72:35 pm
FLO
- MKE
1 stop3h 56m
American Airlines
Deal found 5/29![American Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:45 am
MKE
- MYR
2 stops7h 10m
Southwest
Mon 10/197:05 am
MYR
- MKE
1 stop4h 30m
Southwest
Deal found 5/29![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 am
MKE
- CAE
2 stops8h 21m
United Airlines
Wed 9/96:25 am
CAE
- MKE
1 stop4h 35m
United Airlines
Deal found 5/30![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:50 am
MKE
- AGS
1 stop6h 29m
Delta
Tue 8/188:35 pm
AGS
- MKE
1 stop4h 18m
Delta
Deal found 5/29![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:03 am
MKE
- CHS
1 stop7h 12m
American Airlines
Mon 9/142:05 pm
CHS
- MKE
1 stop6h 58m
American Airlines
Deal found 5/31![American Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:15 am
MKE
- MYR
1 stop7h 15m
Southwest
Wed 8/52:25 pm
MYR
- MKE
2 stops8h 00m
Southwest
Deal found 5/27![Southwest logo]()
$376
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
MKE
- CAE
1 stop7h 12m
United Airlines
Wed 11/1810:18 am
CAE
- MKE
2 stops7h 55m
United Airlines
Deal found 5/31![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:50 am
MKE
- AGS
1 stop6h 29m
Delta
Tue 8/188:35 pm
AGS
- MKE
1 stop4h 18m
Delta
Deal found 5/29![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:05 am
MKE
- CHS
2 stops7h 05m
Southwest
Tue 7/212:10 pm
CHS
- MKE
1 stop4h 05m
Southwest
Deal found 5/30![Southwest logo]()
$376
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:52 pm
MKE
- MYR
2 stops7h 51m
American Airlines
Tue 7/147:07 pm
MYR
- MKE
1 stop5h 45m
American Airlines
Deal found 5/31![American Airlines logo]()
$352
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:14 pm
MKE
- CAE
1 stop6h 29m
Delta
Sun 7/195:35 am
CAE
- MKE
1 stop4h 31m
Delta
Deal found 5/28![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am
MKE
- SAV
1 stop6h 35m
Southwest
Mon 10/265:00 pm
SAV
- MKE
1 stop5h 55m
Southwest
Deal found 5/29![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:52 pm
MKE
- CHS
1 stop4h 12m
United Airlines
Tue 10/2011:55 am
CHS
- MKE
1 stop4h 16m
United Airlines
Deal found 5/31![United Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:03 pm
MKE
- CAE
1 stop4h 47m
Delta
Mon 8/177:47 pm
CAE
- MKE
1 stop5h 06m
Delta
Deal found 5/29![Delta logo]()
$322
Last-minute flights from Milwaukee to South CarolinaDiscover last-minute flight deals from Milwaukee to South Carolina. Data last updated May 31, 2026 and is based on user searches.
Discover last-minute flight deals from Milwaukee to South Carolina. Data last updated May 31, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 am
MKE
- CAE
1 stop6h 22m
Delta
Tue 8/185:40 am
CAE
- MKE
1 stop7h 05m
Delta
Deal found 5/29![Delta logo]()
$312
This Frontier deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Mon 8/178:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/28![Frontier logo]()
$263
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/194:20 pm
MKE
- CAE
1 stop6h 26m
Delta
Tue 8/183:50 pm
CAE
- MKE
1 stop6h 19m
Delta
Deal found 5/29![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:30 am
MKE
- CAE
1 stop4h 50m
American Airlines
Tue 8/187:32 am
CAE
- MKE
1 stop6h 15m
American Airlines
Deal found 5/29![American Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:30 am
MKE
- CAE
1 stop4h 50m
American Airlines
Wed 8/196:46 pm
CAE
- MKE
1 stop6h 10m
American Airlines
Deal found 5/29![American Airlines logo]()
$304
This Frontier deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Mon 8/178:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/29![Frontier logo]()
$258
This Booking.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Wed 8/191:12 pm
CLT
- MKE
1 stop19h 46m
Frontier
Deal found 5/29![Frontier logo]()
$270
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:20 am
MKE
- CAE
1 stop6h 26m
United Airlines
Sat 7/1110:31 am
CAE
- MKE
2 stops9h 55m
United Airlines
Deal found 5/27![United Airlines logo]()
$300
This Booking.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Mon 6/297:58 pm
CLT
- MKE
1 stop13h 00m
Frontier
Deal found 5/30![Frontier logo]()
$281
This Frontier deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Wed 7/88:02 pm
CLT
- MKE
1 stop12h 56m
Frontier
Deal found 5/26![Frontier logo]()
$284
This Booking.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Wed 7/17:58 pm
CLT
- MKE
1 stop13h 00m
Frontier
Deal found 5/27![Frontier logo]()
$296
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:40 am
MKE
- AGS
1 stop5h 47m
Delta
Sun 7/57:25 pm
AGS
- MKE
1 stop5h 34m
Delta
Deal found 5/29![Delta logo]()
$303
One-way flights from Milwaukee to South CarolinaSearch for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
Search for one-way flight options from Milwaukee to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:43 am
MKE
- CLT
1 stop7h 10m
Frontier
Deal found 5/30![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:53 am
MKE
- CLT
1 stop6h 37m
Frontier
Deal found 5/30![Frontier logo]()
$134
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:40 am
MKE
- CLT
2 stops10h 20m
Southwest
Deal found 5/29![Southwest logo]()
$135
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:45 pm
MKE
- CLT
1 stop5h 00m
Southwest
Deal found 5/27![Southwest logo]()
$136
This Booking.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:43 am
MKE
- CLT
1 stop26h 34m
Frontier
Deal found 5/29![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:43 am
MKE
- CLT
1 stop7h 00m
Frontier
Deal found 5/30![Frontier logo]()
$155
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 am
MKE
- MYR
1 stop4h 04m
Delta
Deal found 5/27![Delta logo]()
$168
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:30 pm
MKE
- CLT
1 stop5h 45m
Southwest
Deal found 5/27![Southwest logo]()
$172
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:51 pm
MKE
- CHS
1 stop5h 04m
American Airlines
Deal found 5/28![American Airlines logo]()
$176
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
MKE
- CLT
1 stop4h 10m
Southwest
Deal found 5/27![Southwest logo]()
$177
This Frontier deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:43 am
MKE
- CLT
1 stop7h 00m
Frontier
Deal found 5/30![Frontier logo]()
$179
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am
MKE
- CHS
2 stops9h 25m
Southwest
Deal found 5/28![Southwest logo]()
$181
Find flight deals from Milwaukee to South Carolina
Keep the following information in mind while searching for Milwaukee to South Carolina flight deals. Data was last updated May 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $253 (Delta) |
One-way from | $129 (Frontier) |
Popular in | March |
Cheapest in | January |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Milwaukee to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
Use the filters below to find and compare flights from Milwaukee to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MilwaukeeAugusta
MKE - AGS
MKEAGS
Milwaukee-Mitchell
Wed 10/28
5:45 am-1:16 pm
1 stop6h 31m
Augusta Bush Field
Sat 10/31
11:35 am-3:04 pm
1 stop4h 29m
$261
MilwaukeeAugusta
MKE - AGS
MKEAGS
Milwaukee-Mitchell
Wed 10/28
7:24 am-2:15 pm
1 stop5h 51m
Augusta Bush Field
Sat 10/31
6:18 pm-12:11 am
1 stop6h 53m
$261
MilwaukeeAugusta
MKE - AGS
MKEAGS
Milwaukee-Mitchell
Tue 11/24
12:20 pm-6:47 pm
1 stop5h 27m
Augusta Bush Field
Sat 11/28
7:45 pm-11:49 pm
1 stop5h 04m
$261
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Wed 11/11
12:30 pm-6:32 pm
1 stop5h 02m
Columbia Metropolitan
Wed 11/18
5:18 pm-11:05 pm
1 stop6h 47m
$261
MilwaukeeHilton Head Island
MKE - HHH
MKEHHH
Milwaukee-Mitchell
Tue 7/21
10:11 am-3:29 pm
1 stop4h 18m
Hilton Head Island
Tue 7/28
12:11 pm-10:30 pm
2 stops11h 19m
$276
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Wed 6/24
10:00 am-4:52 pm
1 stop5h 52m
Columbia Metropolitan
Sat 7/11
6:03 pm-11:54 pm
1 stop6h 51m
$292
MilwaukeeSavannah
MKE - SAV
MKESAV
Milwaukee-Mitchell
Sat 9/26
5:00 am-2:16 pm
2 stops8h 16m
Savannah/Hilton Head
Wed 9/30
6:20 am-10:53 am
1 stop5h 33m
$295
MilwaukeeSavannah
MKE - SAV
MKESAV
Milwaukee-Mitchell
Wed 8/26
5:00 am-10:40 am
1 stop4h 40m
Savannah/Hilton Head
Sat 8/29
9:50 am-6:55 pm
2 stops10h 05m
$295
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Mon 6/22
6:40 pm-11:46 pm
1 stop4h 06m
Columbia Metropolitan
Tue 8/18
11:55 am-4:13 pm
1 stop5h 18m
$297
MilwaukeeColumbia
MKE - CAE
MKECAE
Milwaukee-Mitchell
Wed 6/24
6:20 am-1:46 pm
1 stop6h 26m
Columbia Metropolitan
Sat 7/11
10:31 am-7:26 pm
2 stops9h 55m
$300
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Milwaukee to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Milwaukee with our price prediction graph.
MKE-MYR
MKE-CHS
MKE-CLT
MKE-SAV
MKE-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Milwaukee to South Carolina
MKE-USSC
MKE-MYR
MKE-CHS
MKE-CLT
MKE-SAV
What is the cheapest month to book a flight from Milwaukee to South Carolina?
Currently, March is the cheapest month in which you can book a flight from Milwaukee to South Carolina (average of $100). Flying from Milwaukee to South Carolina in April is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Milwaukee to South Carolina?
How far ahead should I book a flight from Milwaukee to South Carolina?
The best time to book flights from Milwaukee to South Carolina is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 31, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Milwaukee to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Milwaukee to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Milwaukee to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Milwaukee to South Carolina by cabin class
Find flights from Milwaukee to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Milwaukee and South Carolina flights
Browse other Milwaukee and South Carolina flight options. Last updated on May 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Milwaukee to South Carolina flights
Consider these flights traveling from Milwaukee to South Carolina.
Top 4 airlines flying from Milwaukee to South Carolina
Discover the top 4 airlines that operate flights from Milwaukee to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$201 | Average$409 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$203 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$370 | FlexibilityNo cancel fee | On-time69% |