HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Milwaukee

$115+ Cheap flights from South Carolina to Milwaukee (MKE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MKE
Jun 17 — Jun 241
Wed 6/17
Wed 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Milwaukee with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Milwaukee

Cheapest flights from South Carolina to Milwaukee
Explore the most affordable flight options available from South Carolina to Milwaukee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.

This Orbitz deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:02 pm
CLT
-
MKE
1 stop12h 56m
Frontier
Thu 7/238:43 am
MKE
-
CLT
1 stop6h 52m
Frontier
Deal found 5/15$228
This Frontier deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:02 pm
CLT
-
MKE
1 stop12h 56m
Frontier
Tue 8/118:43 am
MKE
-
CLT
1 stop6h 52m
Frontier
Deal found 5/16$244
This CheapOair deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:58 pm
CLT
-
MKE
1 stop13h 00m
Frontier
Thu 6/118:53 am
MKE
-
CLT
1 stop6h 37m
Frontier
Deal found 5/13$248
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:29 pm
CAE
-
MKE
1 stop4h 05m
American Airlines
Sat 9/267:24 am
MKE
-
CAE
1 stop3h 53m
American Airlines
Deal found 5/13$261
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:02 pm
CLT
-
MKE
1 stop12h 56m
Frontier
Thu 8/208:43 am
MKE
-
CLT
1 stop7h 00m
Frontier
Deal found 5/13$268
This CheapOair deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:58 pm
CLT
-
MKE
1 stop13h 00m
Frontier
Sun 6/218:43 am
MKE
-
CLT
1 stop25h 51m
Frontier
Deal found 5/16$283
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:24 pm
CLT
-
MKE
1 stop20h 34m
Frontier
Sun 7/198:43 am
MKE
-
CLT
1 stop25h 46m
Frontier
Deal found 5/14$285
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/274:57 pm
CAE
-
MKE
1 stop4h 01m
American Airlines
Thu 7/28:43 am
MKE
-
CAE
1 stop7h 00m
American Airlines
Deal found 5/16$286
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:02 pm
CLT
-
MKE
1 stop12h 56m
Frontier
Thu 8/208:43 am
MKE
-
CLT
1 stop7h 00m
Frontier
Deal found 5/13$288
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:39 pm
CAE
-
MKE
1 stop5h 17m
Delta
Wed 7/156:50 am
MKE
-
CAE
1 stop5h 09m
Delta
Deal found 5/17$296
This CheapOair deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:33 pm
CLT
-
MKE
1 stop6h 42m
Frontier
Thu 10/158:10 pm
MKE
-
CLT
1 stop23h 55m
Frontier
Deal found 5/15$298
This CheapOair deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:24 pm
CLT
-
MKE
1 stop20h 34m
Frontier
Tue 7/218:43 am
MKE
-
CLT
1 stop25h 46m
Frontier
Deal found 5/15$299

Find flight deals from South Carolina to Milwaukee

Keep the following information in mind while searching for South Carolina to Milwaukee flight deals. Data was last updated May 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$228
(Orbitz)

One-way from

$115
(Frontier)

Popular in

August

Cheapest in

May

Average price

$195
Provider with most accurate pricing for Myrtle Beach Intl-Milwaukee-Mitchell flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Milwaukee-Mitchell flights.
Search Deals
From South Carolina to Milwaukee-Mitchell
Search Deals
One-way flight from South Carolina to Milwaukee-Mitchell
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from South Carolina to Milwaukee that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 6/27

4:57 pm-9:06 pm

1 stop5h 09m

Milwaukee-Mitchell

Thu 7/9

8:43 am-4:43 pm

1 stop7h 00m

$286

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Fri 7/10

7:39 pm-11:56 pm

1 stop5h 17m

Milwaukee-Mitchell

Wed 7/15

6:50 am-12:59 pm

1 stop5h 09m

$296

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 6/13

6:00 am-9:18 am

1 stop4h 18m

Milwaukee-Mitchell

Wed 6/17

5:40 am-1:02 pm

1 stop6h 22m

$296

Hilton Head IslandMilwaukee

HHH - MKE

HHHMKE

Hilton Head Island

Thu 5/28

2:43 pm-11:47 pm

2 stops10h 04m

Milwaukee-Mitchell

Mon 6/1

8:12 am-1:33 pm

1 stop4h 21m

$305

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 9/26

5:25 pm-10:59 pm

1 stop6h 34m

Milwaukee-Mitchell

Wed 9/30

5:00 am-10:10 am

1 stop4h 10m

$341

Hilton Head IslandMilwaukee

HHH - MKE

HHHMKE

Hilton Head Island

Tue 6/23

5:21 pm-12:02 am

2 stops7h 41m

Milwaukee-Mitchell

Tue 6/30

7:00 am-2:13 pm

1 stop6h 13m

$346

Myrtle BeachMilwaukee

MYR - MKE

MYRMKE

Myrtle Beach Intl

Tue 8/4

6:00 am-9:16 am

1 stop4h 16m

Milwaukee-Mitchell

Wed 8/12

5:19 pm-11:30 pm

1 stop5h 11m

$347

Hilton Head IslandMilwaukee

HHH - MKE

HHHMKE

Hilton Head Island

Tue 6/23

4:15 pm-10:17 pm

1 stop7h 02m

Milwaukee-Mitchell

Tue 6/30

10:08 am-3:32 pm

1 stop4h 24m

$348

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Fri 6/19

6:01 pm-11:59 pm

1 stop6h 58m

Milwaukee-Mitchell

Mon 6/22

6:40 pm-11:46 pm

1 stop4h 06m

$350

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Tue 6/2

6:03 pm-12:02 am

2 stops6h 59m

Milwaukee-Mitchell

Sat 6/6

10:00 am-4:27 pm

1 stop5h 27m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/17

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from South Carolina to Milwaukee

Have a flexible travel schedule? Discover the best time to fly to Milwaukee from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Milwaukee

What is the cheapest month to book a flight from South Carolina to Milwaukee?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $82). Flying from South Carolina to Milwaukee in April is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Milwaukee?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Milwaukee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Milwaukee from South Carolina?

    For a flight from South Carolina to Milwaukee, you will be flying into Milwaukee-Mitchell. Milwaukee-Mitchell (MKE) is just 6.4 mi from the center of the city.

  • How long is the flight from South Carolina to Milwaukee?

    For as low as $286, American Airlines can have you in Milwaukee from South Carolina in 5h 09m. South Carolina and Milwaukee are separated by a distance of 721 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Milwaukee one-way?

    The cheapest airlines for a one-way flight from South Carolina to Milwaukee are American Airlines ($90), United Airlines ($104), and Southwest ($118).

  • What are the most popular routes from South Carolina to Milwaukee?

    The most popular flight routes from South Carolina to Milwaukee are Charlotte Douglas - Milwaukee-Mitchell, Charleston - Milwaukee-Mitchell and Savannah/Hilton Head - Milwaukee-Mitchell.

  • Can I find deals for flights from South Carolina to Milwaukee that include hotel bookings?

    Yes. In addition to deals on South Carolina to Milwaukee flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Milwaukee?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Milwaukee.

  • Can I find deals for business class flights from South Carolina to Milwaukee?

    Yes. Cheapflights offers flight deals from South Carolina to Milwaukee by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Milwaukee?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $82). Flying from South Carolina to Milwaukee in April is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
Port Washington
New Berlin
Oak Creek
Wauwatosa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Milwaukee

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to O'Hare Intl flights
Newark to O'Hare Intl flights
LaGuardia to O'Hare Intl flights
Los Angeles to O'Hare Intl flights
John F Kennedy Intl to O'Hare Intl flights
Seattle to O'Hare Intl flights
Baltimore to O'Hare Intl flights
Hobby to O'Hare Intl flights
San Francisco to O'Hare Intl flights
Philadelphia to O'Hare Intl flights
Reagan-National to O'Hare Intl flights
Denver to O'Hare Intl flights
Dulles Intl to O'Hare Intl flights
George Bush Intcntl to O'Hare Intl flights
Boston to O'Hare Intl flights
Ontario to O'Hare Intl flights
Orlando to O'Hare Intl flights
Tampa to O'Hare Intl flights
Sky Harbor Intl to O'Hare Intl flights
Atlanta to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Dallas/Fort Worth to Minneapolis flights
Austin to O'Hare Intl flights
Raleigh to O'Hare Intl flights
San Diego to O'Hare Intl flights
Miami to O'Hare Intl flights
Seattle to Minneapolis flights
Santa Ana to O'Hare Intl flights
Newark to Minneapolis flights
Los Angeles to Minneapolis flights
Charlotte to O'Hare Intl flights
LaGuardia to Minneapolis flights
Dulles Intl to Minneapolis flights
Minneapolis to O'Hare Intl flights
San Jose to O'Hare Intl flights
Reagan-National to Minneapolis flights
Boston to Minneapolis flights
Baltimore to Minneapolis flights
San Francisco to Minneapolis flights
Hartford to O'Hare Intl flights
Sky Harbor Intl to Minneapolis flights
New Orleans to O'Hare Intl flights
Sacramento to O'Hare Intl flights
John F Kennedy Intl to Minneapolis flights
Portland to O'Hare Intl flights
Love Field to O'Hare Intl flights
Denver to Minneapolis flights
Newark to Milwaukee flights
Kansas City to O'Hare Intl flights
Hobby to Minneapolis flights

Top 4 airlines flying from South Carolina to Milwaukee

Discover the top 4 airlines that operate flights from South Carolina to Milwaukee. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$168Average$369FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$406FlexibilityNo cancel feeOn-time63%
DeltaCheapest$226Average$366FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$293Average$404FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.