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Des Moines

$395+ Cheap flights from Tallahassee to Des Moines (TLH - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
TLH — DSM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Tallahassee to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Tallahassee (TLH) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$395
(Delta)

Popular in

January

Cheapest in

August

Average price

$608
From Tallahassee to Des Moines
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($183 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($47 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Tallahassee to Des Moines

Cheapest flights from Tallahassee to Des Moines
Explore the most affordable flight options available from Tallahassee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:12 pmTLH - DSM
1 stop6h 25mDelta
Sat 10/45:12 pmDSM - TLH
1 stop4h 24mDelta
Deal found 9/15$395
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:23 amTLH - DSM
2 stops9h 01mAmerican Airlines
Sat 10/46:00 amDSM - TLH
2 stops10h 03mAmerican Airlines
Deal found 9/15$405
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:45 pmTLH - DSM
1 stop5h 21mAmerican Airlines
Sat 9/203:46 pmDSM - TLH
1 stop5h 38mAmerican Airlines
Deal found 9/15$450
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/151:09 pmTLH - DSM
2 stops11h 19mAmerican Airlines
Tue 9/237:03 amDSM - TLH
2 stops10h 13mAmerican Airlines
Deal found 9/15$460
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:15 amTLH - DSM
2 stops10h 05mAmerican Airlines
Sun 10/56:00 amDSM - TLH
2 stops8h 08mAmerican Airlines
Deal found 9/16$575
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/244:21 pmTLH - DSM
2 stops8h 38mAmerican Airlines
Sun 10/266:44 amDSM - TLH
1 stop7h 25mAmerican Airlines
Deal found 9/15$614
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:49 pmTLH - DSM
1 stop4h 53mAmerican Airlines
Sun 10/265:00 amDSM - TLH
1 stop7h 34mAmerican Airlines
Deal found 9/15$696

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tallahassee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Tallahassee to Des Moines that are best for you.

Fly from

Tallahassee

Fly to

Des Moines

Route

Depart

Return

Price

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Tue 9/30

5:12 pm-10:37 pm

1 stop6h 25m

Des Moines

Sat 10/4

5:12 pm-10:36 pm

1 stop4h 24m

$395

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Tue 9/30

7:23 am-3:24 pm

2 stops9h 01m

Des Moines

Sat 10/4

6:00 am-5:03 pm

2 stops10h 03m

$405

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Tue 3/10

6:01 pm-9:53 pm

1 stop4h 52m

Des Moines

Thu 3/19

7:01 am-1:32 pm

1 stop5h 31m

$412

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Wed 3/11

8:47 am-12:31 pm

1 stop4h 44m

Des Moines

Thu 3/19

7:14 am-2:44 pm

1 stop6h 30m

$412

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Wed 3/11

5:35 am-10:23 am

1 stop5h 48m

Des Moines

Fri 3/20

5:15 pm-10:22 pm

1 stop4h 07m

$418

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Wed 10/1

6:31 pm-11:13 pm

1 stop5h 42m

Des Moines

Sun 10/5

5:11 am-1:39 pm

1 stop7h 28m

$450

TallahasseeDes Moines

TLH - DSM

TLHDSM

Tallahassee

Wed 3/11

7:24 am-12:19 pm

1 stop5h 55m

Des Moines

Fri 3/20

1:05 pm-12:11 am

2 stops10h 06m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Tallahassee to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tallahassee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tallahassee to Des Moines

What is the cheapest time of day to fly from TLH to DSM?

Find hourly flight availability from Tallahassee to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

A simple way to save on the total cost of your ticket is to fly from Tallahassee to Des Moines in the morning. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight at noon.

How much does it cost to fly round-trip from Tallahassee to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta from Tallahassee to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Tallahassee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tallahassee to Des Moines?

    Delta and American Airlines can get you from Tallahassee to Des Moines in just under 6h 25m. Your travel time can differ by up to 2h 36m. Airlines will cover a distance of 927 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Tallahassee to Des Moines round-trip?

    Currently priced at $442, Delta will fly you from Tallahassee to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Delta is priced at 24% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Tallahassee to Des Moines that include hotel bookings?

    Yes. In addition to deals on Tallahassee to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tallahassee to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tallahassee to Des Moines.

  • Can I find deals for business class flights from Tallahassee to Des Moines?

    Yes. Cheapflights offers flight deals from Tallahassee to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tallahassee to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Tallahassee to Des Moines (average of $336). Flying from Tallahassee to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top airline flying from Tallahassee to Des Moines

Discover the top airline that operate flights from Tallahassee to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$442Average$662FlexibilityNo cancel feeOn-timeN/A

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