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La Crosse

$322+ Cheap flights from Jacksonville to La Crosse (JAX - LSE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — LSE
Mai 30 — Jun 61
Sa 5/30
Sa 6/6
1 adult, Economy
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Cheap flight deals from Jacksonville to La Crosse

Cheapest flights from Jacksonville to La Crosse
Explore the most affordable flight options available from Jacksonville to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/16:50 am
JAX
-
LSE
1 stop5h 30m
American Airlines
Di 7/711:45 am
LSE
-
JAX
1 stop4h 36m
American Airlines
Deal found 4/25$328
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/137:14 pm
JAX
-
LSE
1 stop5h 40m
American Airlines
Mi 5/205:40 am
LSE
-
JAX
2 stops11h 14m
American Airlines
Deal found 4/29$349
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 5/266:50 am
JAX
-
LSE
1 stop5h 32m
American Airlines
Sa 5/3011:44 am
LSE
-
JAX
2 stops11h 20m
American Airlines
Deal found 4/28$424

Find flight deals from Jacksonville to La Crosse

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$328
(American Airlines)

One-way from

$322
(Kiwi.com)
Provider with most accurate pricing for Jacksonville-La Crosse flight deals.
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Provider most trusted by Cheapflights users for Jacksonville-La Crosse flights.
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From Jacksonville to La Crosse
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One-way flight from Jacksonville to La Crosse
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Jacksonville to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Mi 7/1

6:50 am-11:20 am

1 stop5h 30m

La Crosse

Di 7/7

11:45 am-5:21 pm

1 stop4h 36m

$328

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Mi 5/13

7:14 pm-11:54 pm

1 stop5h 40m

La Crosse

Mi 5/20

5:40 am-5:54 pm

2 stops11h 14m

$349

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Di 5/26

6:50 am-11:22 am

1 stop5h 32m

La Crosse

Sa 5/30

11:44 am-12:04 am

2 stops11h 20m

$424
Cheapest one-way

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Do 7/16

9:23 am-7:14 pm

3 stops34h 51m

$322

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Do 7/16

7:00 am-11:59 pm

1 stop17h 59m

$340
Quickest one-way

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Mo 9/21

11:02 am-11:15 pm

2 stops13h 13m

$372

JacksonvilleLa Crosse

JAX - LSE

JAXLSE

Jacksonville

Sa 5/30

4:23 pm-9:08 am

2 stops41h 45m

$613

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Jacksonville-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-La Crosse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing La Crosse

Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated April 30, 2026.
Read through reviews of airlines operating flights from Jacksonville to La Crosse, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,681 reviews

Comfort

7.2

Boarding

7.5

Overall

7.1

Food

6.4

Crew

7.9

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,681 reviews
American Airlines
7.1
Good
11,681 reviews

Comfort

7.2

Boarding

7.5

Overall

7.1

Food

6.4

Crew

7.9

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to La Crosse?

    Airlines like American Airlines fly from Jacksonville to La Crosse in about 5h 30m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 1062 mi.

  • Can I find deals for flights from Jacksonville to La Crosse that include hotel bookings?

    Yes. In addition to deals on Jacksonville to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to La Crosse.

  • Can I find deals for business class flights from Jacksonville to La Crosse?

    Yes. Cheapflights offers flight deals from Jacksonville to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Decorah
Winona

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Top airline flying from Jacksonville to La Crosse

Discover the top airline that operate flights from Jacksonville to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$449Average$512FlexibilityNo cancel feeOn-time71%

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