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Des Moines

$57+ Cheap flights from Ohio to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — DSM
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheap flight deals from Ohio to Des Moines

Keep the following information in mind while searching for Ohio to Des Moines flight deals. Data was last updated September 19, 2025.

Round-trip from

$171
(Priceline)

One-way from

$57
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$326
From Ohio to Des Moines
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One-way flight from Ohio to Des Moines
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Highest demand for flights based on searches. 24% potential increase in price ($137 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Ohio to Des Moines

Cheapest flights from Ohio to Des Moines
Explore the most affordable flight options available from Ohio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This Priceline deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:10 amDTW - DSM
1 stop8h 30mFrontier
Mon 10/62:25 pmDSM - DTW
1 stop9h 21mFrontier
Deal found 9/17$171
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:00 amDTW - DSM
1 stop8h 52mFrontier
Thu 10/232:37 pmDSM - DTW
1 stop9h 22mFrontier
Deal found 9/16$194
This Priceline deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:05 amCVG - DSM
1 stop8h 42mFrontier
Sun 11/22:32 pmDSM - CVG
1 stop10h 07mFrontier
Deal found 9/17$215
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:00 amDTW - DSM
1 stop8h 52mMultiple Airlines
Sun 10/268:47 pmDSM - DTW
1 stop15h 33mMultiple Airlines
Deal found 9/18$221
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amDTW - DSM
1 stop8h 52mMultiple Airlines
Sun 10/268:47 pmDSM - DTW
1 stop15h 33mMultiple Airlines
Deal found 9/16$245
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:41 amDTW - DSM
2 stops24h 10mMultiple Airlines
Mon 10/68:30 amDSM - DTW
1 stop15h 15mMultiple Airlines
Deal found 9/16$253
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:21 pmCMH - DSM
1 stop4h 16mAmerican Airlines
Sat 11/84:03 pmDSM - CMH
1 stop7h 34mAmerican Airlines
Deal found 9/17$257
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:16 pmCLE - DSM
1 stop7h 57mMultiple Airlines
Sun 11/910:50 amDSM - CLE
1 stop23h 30mMultiple Airlines
Deal found 9/16$259
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:15 amDTW - DSM
1 stop8h 44mMultiple Airlines
Sun 10/268:47 pmDSM - DTW
1 stop15h 33mMultiple Airlines
Deal found 9/16$260
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:05 amCVG - DSM
1 stop8h 44mFrontier
Sun 11/162:32 pmDSM - CVG
1 stop10h 07mFrontier
Deal found 9/17$262
This Priceline deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:10 amDTW - DSM
1 stop8h 30mFrontier
Thu 9/252:25 pmDSM - DTW
1 stop9h 21mFrontier
Deal found 9/17$263
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:00 amDAY - DSM
1 stop6h 14mUnited Airlines
Tue 11/253:15 pmDSM - DAY
1 stop4h 00mUnited Airlines
Deal found 9/17$268

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Ohio to Des Moines that are best for you.

Fly from

Ohio

Fly to

Des Moines

Route

Depart

Return

Price

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Fri 10/31

6:05 am-1:47 pm

1 stop8h 42m

Des Moines

Sun 11/2

2:32 pm-1:39 am

1 stop10h 07m

$215

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 10/23

6:00 am-1:52 pm

1 stop8h 52m

Des Moines

Sun 10/26

8:47 pm-1:20 pm

1 stop15h 33m

$221

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Fri 11/14

6:05 am-1:49 pm

1 stop8h 44m

Des Moines

Sun 11/16

2:32 pm-1:39 am

1 stop10h 07m

$262

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Fri 11/21

7:00 am-12:14 pm

1 stop6h 14m

Des Moines

Tue 11/25

3:15 pm-8:15 pm

1 stop4h 00m

$268

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Wed 10/1

10:41 am-9:51 am

2 stops24h 10m

Des Moines

Sun 10/5

8:47 pm-1:20 pm

1 stop15h 33m

$270

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Fri 12/12

8:00 am-12:55 pm

1 stop5h 55m

Des Moines

Sun 12/14

2:56 pm-10:37 pm

1 stop30h 41m

$274

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Thu 10/2

6:00 am-1:01 pm

1 stop8h 01m

Des Moines

Mon 10/6

11:25 am-8:16 pm

1 stop7h 51m

$276

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Wed 10/22

6:00 am-1:52 pm

1 stop8h 52m

Des Moines

Sun 10/26

6:30 am-8:16 am

2 stops24h 46m

$279

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Fri 1/9

3:38 pm-10:17 pm

1 stop7h 39m

Des Moines

Sun 1/11

7:15 am-3:03 pm

1 stop6h 48m

$283

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Wed 10/1

5:55 pm-9:50 pm

1 stop4h 55m

Des Moines

Sun 10/5

1:00 pm-8:09 pm

1 stop6h 09m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Des Moines

What is the cheapest month to book a flight from Ohio to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $336). Flying from Ohio to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to DSM?

Find hourly flight availability from Ohio to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2025.

When flying from Ohio to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Ohio?

    If you book a flight to Des Moines from Ohio, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Ohio to Des Moines?

    There are many flights that can get you from Ohio to Des Moines in 6h 14m. Fly via Frontier, United Airlines, or Allegiant Air to get the fastest option. The distance between Ohio and Des Moines is about 506 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Ohio to Des Moines one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $137. American Airlines flights start at $164 while deals on Southwest start at $189 one-way.

  • What are the most popular routes from Ohio to Des Moines?

    While some choose either Columbus - Des Moines or Cincinnati Cinci./N. Kentucky - Des Moines, Detroit Metropolitan Wayne County - Des Moines is the most popular route from Ohio to Des Moines.

  • Can I find deals for flights from Ohio to Des Moines that include hotel bookings?

    Yes. In addition to deals on Ohio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Des Moines.

  • Can I find deals for business class flights from Ohio to Des Moines?

    Yes. Cheapflights offers flight deals from Ohio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $336). Flying from Ohio to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Ohio to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Ohio to Des Moines

Discover the top 4 airlines that operate flights from Ohio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$163Average$374FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$364FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$243Average$412FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$381FlexibilityNo cancel feeOn-time63%

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