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Des Moines

$89+ Cheap flights from Ohio to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — DSM
Mar 8 — Mar 151
Sun 3/8
Sun 3/15
1 adult, Economy
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Cheap flight deals from Ohio to Des Moines

Cheapest flights from Ohio to Des Moines
Explore the most affordable flight options available from Ohio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.

This Frontier deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/128:56 pm
DTW
-
DSM
1 stop13h 34m
Frontier
Mon 3/168:21 pm
DSM
-
DTW
1 stop13h 38m
Frontier
Deal found 2/6$217
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:34 pm
DTW
-
DSM
2 stops26h 27m
Multiple Airlines
Mon 3/168:21 pm
DSM
-
DTW
1 stop13h 38m
Multiple Airlines
Deal found 2/6$259
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:15 am
CAK
-
DSM
1 stop5h 21m
United Airlines
Sun 4/51:10 pm
DSM
-
CAK
1 stop6h 15m
United Airlines
Deal found 2/5$269
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/211:55 pm
CAK
-
DSM
1 stop4h 52m
United Airlines
Wed 2/256:55 pm
DSM
-
CAK
1 stop4h 01m
United Airlines
Deal found 2/5$279
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:20 am
DAY
-
DSM
1 stop6h 57m
American Airlines
Tue 2/241:38 pm
DSM
-
DAY
1 stop6h 22m
American Airlines
Deal found 2/5$279
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:58 am
CVG
-
DSM
1 stop8h 18m
Multiple Airlines
Sun 3/87:00 am
DSM
-
CVG
2 stops26h 48m
Multiple Airlines
Deal found 2/6$279
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
DAY
-
DSM
1 stop6h 01m
Delta
Tue 2/246:19 am
DSM
-
DAY
2 stops10h 38m
Delta
Deal found 2/5$284
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:54 am
DTW
-
DSM
1 stop8h 22m
Multiple Airlines
Sun 3/87:00 am
DSM
-
DTW
2 stops26h 59m
Multiple Airlines
Deal found 2/4$284
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1411:54 am
DTW
-
DSM
1 stop8h 22m
Frontier
Mon 3/168:21 pm
DSM
-
DTW
1 stop13h 38m
Frontier
Deal found 2/5$288
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
DTW
-
DSM
1 stop13h 42m
Multiple Airlines
Sun 3/87:00 am
DSM
-
DTW
2 stops40h 39m
Multiple Airlines
Deal found 2/6$292
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:35 pm
DTW
-
DSM
2 stops29h 07m
Multiple Airlines
Sun 3/17:27 pm
DSM
-
DTW
1 stop21h 40m
Multiple Airlines
Deal found 2/4$294
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PIT
-
DSM
1 stop6h 19m
Delta
Wed 3/44:20 pm
DSM
-
PIT
1 stop6h 39m
Delta
Deal found 2/4$297

Find flight deals from Ohio to Des Moines

Keep the following information in mind while searching for Ohio to Des Moines flight deals. Data was last updated February 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(Frontier)

One-way from

$89
(Kiwi.com)

Popular in

January

Cheapest in

November

Average price

$377
Provider with most accurate pricing for Cleveland Hopkins Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Des Moines flights.
Search Deals
From Ohio to Des Moines
Search Deals
One-way flight from Ohio to Des Moines
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Ohio to Des Moines that are best for you.

Fly from

Ohio

Fly to

Des Moines

Route

Depart

Return

Price

AkronDes Moines

CAK - DSM

CAKDSM

Akron/Canton

Fri 4/3

10:15 am-2:36 pm

1 stop5h 21m

Des Moines

Sun 4/5

1:10 pm-8:25 pm

1 stop6h 15m

$269

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Fri 2/20

7:20 am-1:17 pm

1 stop6h 57m

Des Moines

Tue 2/24

1:38 pm-9:00 pm

1 stop6h 22m

$279

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Fri 3/6

11:58 am-7:16 pm

1 stop8h 18m

Des Moines

Sun 3/8

7:00 am-10:48 am

2 stops26h 48m

$279

AkronDes Moines

CAK - DSM

CAKDSM

Akron/Canton

Sat 2/21

1:55 pm-5:47 pm

1 stop4h 52m

Des Moines

Wed 2/25

6:55 pm-11:56 pm

1 stop4h 01m

$279

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Fri 2/20

6:00 am-11:01 am

1 stop6h 01m

Des Moines

Tue 2/24

6:19 am-5:57 pm

2 stops10h 38m

$284

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Wed 2/25

2:35 pm-6:42 pm

2 stops29h 07m

Des Moines

Sun 3/1

7:27 pm-6:07 pm

1 stop21h 40m

$294

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Tue 3/3

6:00 am-11:19 am

1 stop6h 19m

Des Moines

Wed 3/4

4:20 pm-11:59 pm

1 stop6h 39m

$297

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Tue 3/3

9:05 am-1:04 pm

1 stop4h 59m

Des Moines

Tue 3/3

7:44 pm-12:46 am

1 stop4h 02m

$297

PittsburghDes Moines

PIT - DSM

PITDSM

Pittsburgh

Wed 3/4

9:13 am-1:05 pm

1 stop4h 52m

Des Moines

Wed 3/4

7:44 pm-12:46 am

1 stop4h 02m

$297

ClevelandDes Moines

CLE - DSM

CLEDSM

Cleveland Hopkins Intl

Wed 3/4

6:30 am-10:17 am

1 stop4h 47m

Des Moines

Wed 3/4

4:20 pm-11:06 pm

1 stop5h 46m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/6

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Des Moines

What is the cheapest month to book a flight from Ohio to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $143). Flying from Ohio to Des Moines in January is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Ohio?

    If you book a flight to Des Moines from Ohio, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Ohio to Des Moines?

    There are many flights that can get you from Ohio to Des Moines in 5h 21m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. The distance between Ohio and Des Moines is about 635 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Ohio to Des Moines one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $118. American Airlines flights start at $118 while deals on Delta start at $121 one-way.

  • What are the most popular routes from Ohio to Des Moines?

    While some choose either Columbus - Des Moines or Cleveland Hopkins Intl - Des Moines, Detroit Metropolitan Wayne County - Des Moines is the most popular route from Ohio to Des Moines.

  • Can I find deals for flights from Ohio to Des Moines that include hotel bookings?

    Yes. In addition to deals on Ohio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Des Moines.

  • Can I find deals for business class flights from Ohio to Des Moines?

    Yes. Cheapflights offers flight deals from Ohio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $143). Flying from Ohio to Des Moines in January is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Ohio to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Ohio to Des Moines

Discover the top 4 airlines that operate flights from Ohio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$143Average$341FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$363FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$381FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$395FlexibilityNo cancel feeOn-time63%

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