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Des Moines

$82+ Cheap flights from Ohio to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — DSM
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Ohio to Des Moines

Keep the following information in mind while searching for Ohio to Des Moines flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$150
(Frontier)

One-way from

$82
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$491
Provider with most accurate pricing for Cleveland Hopkins Intl-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Des Moines flights.
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From Ohio to Des Moines
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One-way flight from Ohio to Des Moines
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Highest demand for flights based on searches. 23% potential increase in price ($131 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Ohio to Des Moines

Cheapest flights from Ohio to Des Moines
Explore the most affordable flight options available from Ohio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:20 pmCLE - DSM
1 stop23h 43mMultiple Airlines
Thu 12/112:56 pmDSM - CLE
1 stop21h 49mMultiple Airlines
Deal found 11/4$177
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:46 pmDTW - DSM
1 stop21h 12mMultiple Airlines
Mon 11/248:00 amDSM - DTW
1 stop16h 08mMultiple Airlines
Deal found 11/4$189
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:46 pmDTW - DSM
1 stop21h 12mMultiple Airlines
Sun 11/238:19 pmDSM - DTW
1 stop14h 24mMultiple Airlines
Deal found 11/6$206
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amCLE - DSM
1 stop13h 38mMultiple Airlines
Wed 11/261:56 pmDSM - CLE
1 stop29h 56mMultiple Airlines
Deal found 11/4$212
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:29 pmDTW - DSM
2 stops21h 09mFrontier
Sun 11/238:19 pmDSM - DTW
1 stop14h 24mFrontier
Deal found 11/6$226
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amCLE - DSM
1 stop9h 58mMultiple Airlines
Mon 11/178:40 amDSM - CLE
2 stops28h 34mMultiple Airlines
Deal found 11/4$242
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:45 amDTW - DSM
1 stop13h 53mMultiple Airlines
Tue 11/254:03 pmDSM - DTW
1 stop17h 14mMultiple Airlines
Deal found 11/6$248
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:08 amCAK - DSM
1 stop4h 34mAmerican Airlines
Wed 12/105:01 pmDSM - CAK
1 stop4h 52mAmerican Airlines
Deal found 11/5$249
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amDAY - DSM
1 stop5h 38mDelta
Sat 12/133:00 pmDSM - DAY
1 stop7h 11mDelta
Deal found 11/6$249
This Priceline deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:05 amCVG - DSM
1 stop8h 51mFrontier
Mon 11/172:32 pmDSM - CVG
1 stop10h 07mFrontier
Deal found 11/5$250
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:45 amCLE - DSM
1 stop27h 44mMultiple Airlines
Sun 11/238:19 pmDSM - CLE
2 stops15h 04mMultiple Airlines
Deal found 11/4$251
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:42 pmDTW - DSM
2 stops27h 39mMultiple Airlines
Mon 12/156:35 amDSM - DTW
1 stop8h 05mMultiple Airlines
Deal found 11/5$253

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Ohio to Des Moines that are best for you.

Fly from

Ohio

Fly to

Des Moines

Route

Depart

Return

Price

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 11/20

6:46 pm-2:58 pm

1 stop21h 12m

Des Moines

Sun 11/23

8:19 pm-11:43 am

1 stop14h 24m

$206

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 11/21

5:45 am-6:38 pm

1 stop13h 53m

Des Moines

Tue 11/25

4:03 pm-10:17 am

1 stop17h 14m

$248

AkronDes Moines

CAK - DSM

CAKDSM

Akron/Canton

Fri 12/5

8:08 am-11:42 am

1 stop4h 34m

Des Moines

Wed 12/10

5:01 pm-10:53 pm

1 stop4h 52m

$249

AkronDes Moines

CAK - DSM

CAKDSM

Akron/Canton

Sun 3/29

8:40 am-2:11 pm

1 stop6h 31m

Des Moines

Sat 4/4

3:15 pm-8:27 pm

1 stop4h 12m

$249

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Sat 12/6

6:00 am-10:38 am

1 stop5h 38m

Des Moines

Sat 12/13

3:00 pm-11:11 pm

1 stop7h 11m

$249

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Wed 12/3

6:39 pm-10:34 pm

1 stop4h 55m

Des Moines

Wed 12/10

6:17 am-1:26 pm

1 stop6h 09m

$257

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Thu 12/4

8:55 pm-11:52 pm

1 stop3h 57m

Des Moines

Tue 12/9

3:18 pm-11:09 pm

1 stop6h 51m

$279

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Fri 11/21

7:00 am-12:14 pm

1 stop6h 14m

Des Moines

Sun 11/23

1:05 pm-8:15 pm

1 stop6h 10m

$279

ColumbusDes Moines

CMH - DSM

CMHDSM

Columbus

Wed 11/19

7:30 am-8:29 am

1 stop25h 59m

Des Moines

Sun 11/23

8:19 pm-7:11 pm

2 stops21h 52m

$279

DaytonDes Moines

DAY - DSM

DAYDSM

Dayton

Fri 11/21

6:00 am-10:42 am

1 stop5h 42m

Des Moines

Sun 11/23

5:35 am-12:37 pm

1 stop6h 02m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Des Moines

What is the cheapest month to book a flight from Ohio to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $143). Flying from Ohio to Des Moines in December is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to DSM?

Find hourly flight availability from Ohio to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

It’s typically best to fly out from Ohio to Des Moines in the evening. Doing so could potentially save you 25% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Ohio to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Ohio to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to Des Moines flight should consider departing on Saturday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Ohio?

    If you book a flight to Des Moines from Ohio, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Ohio to Des Moines?

    There are many flights that can get you from Ohio to Des Moines in 4h 34m. Fly via American Airlines, United Airlines, or Delta to get the fastest option. The distance between Ohio and Des Moines is about 635 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Ohio to Des Moines one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $114. Allegiant Air flights start at $130 while deals on Delta start at $184 one-way.

  • What are the most popular routes from Ohio to Des Moines?

    While some choose either Columbus - Des Moines or Dayton - Des Moines, Detroit Metropolitan Wayne County - Des Moines is the most popular route from Ohio to Des Moines.

  • Can I find deals for flights from Ohio to Des Moines that include hotel bookings?

    Yes. In addition to deals on Ohio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Des Moines.

  • Can I find deals for business class flights from Ohio to Des Moines?

    Yes. Cheapflights offers flight deals from Ohio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Ohio to Des Moines (average of $143). Flying from Ohio to Des Moines in December is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Ohio to Des Moines

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Top 4 airlines flying from Ohio to Des Moines

Discover the top 4 airlines that operate flights from Ohio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$163Average$393FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$374FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$243Average$406FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$381FlexibilityNo cancel feeOn-time63%

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