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Des Moines

$81+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — DSM
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amRDU - DSM
1 stop6h 28mDelta
Thu 1/86:24 amDSM - RDU
1 stop4h 38mDelta
Deal found 12/10$289
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:53 pmTYS - DSM
1 stop9h 39mAllegiant Air
Tue 12/237:30 amDSM - TYS
1 stop28h 32mAllegiant Air
Deal found 12/10$312
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:55 amRDU - DSM
2 stops6h 58mAmerican Airlines
Thu 1/84:00 pmDSM - RDU
1 stop5h 38mAmerican Airlines
Deal found 12/10$318
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amCLT - DSM
1 stop17h 10mMultiple Airlines
Mon 1/56:35 amDSM - CLT
1 stop27h 28mMultiple Airlines
Deal found 12/9$320
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:03 pmTYS - DSM
1 stop21h 28mAllegiant Air
Sun 12/212:56 pmDSM - TYS
1 stop18h 35mAllegiant Air
Deal found 12/10$350
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:53 pmAVL - DSM
1 stop10h 33mAllegiant Air
Wed 12/248:31 amDSM - AVL
2 stops37h 33mAllegiant Air
Deal found 12/11$364
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amRDU - DSM
2 stops9h 33mUnited Airlines
Thu 1/88:00 amDSM - RDU
2 stops12h 05mUnited Airlines
Deal found 12/10$369
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amRDU - DSM
1 stop7h 21mAmerican Airlines
Sun 1/46:26 pmDSM - RDU
1 stop4h 30mAmerican Airlines
Deal found 12/9$379
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:30 pmILM - DSM
1 stop7h 05mAmerican Airlines
Tue 12/231:18 pmDSM - ILM
2 stops9h 41mAmerican Airlines
Deal found 12/10$388
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:56 pmAVL - DSM
1 stop24h 06mAllegiant Air
Wed 12/1711:15 amDSM - AVL
1 stop21h 50mAllegiant Air
Deal found 12/11$388
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amRDU - DSM
1 stop6h 42mAmerican Airlines
Wed 12/313:26 pmDSM - RDU
1 stop7h 33mAmerican Airlines
Deal found 12/11$391
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:00 amTYS - DSM
1 stop7h 21mAmerican Airlines
Tue 12/306:52 pmDSM - TYS
1 stop14h 58mAmerican Airlines
Deal found 12/11$393

Find flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$227
(Mytrip)

One-way from

$81
(Frontier)

Popular in

February

Cheapest in

December

Average price

$327

Good round-trip deal

$397 or less
Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.
Search Deals
From North Carolina to Des Moines
Search Deals
One-way flight from North Carolina to Des Moines
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from North Carolina to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

North Carolina

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 1/8

1:24 pm-10:46 pm

1 stop10h 22m

Des Moines

Mon 1/12

11:09 am-10:55 am

2 stops22h 46m

$227

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 12/25

6:00 am-11:28 am

1 stop6h 28m

Des Moines

Thu 1/8

6:24 am-12:02 pm

1 stop4h 38m

$289

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 1/21

2:15 pm-10:09 pm

2 stops32h 54m

Des Moines

Mon 1/26

6:30 am-9:01 pm

1 stop13h 31m

$289

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 1/21

4:07 pm-11:44 pm

1 stop8h 37m

Des Moines

Mon 1/26

3:35 pm-9:19 pm

1 stop4h 44m

$290

NorfolkDes Moines

ORF - DSM

ORFDSM

Norfolk

Sun 1/18

5:35 am-11:24 am

1 stop6h 49m

Des Moines

Sat 1/24

10:59 am-5:34 pm

1 stop5h 35m

$293

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 1/20

10:00 am-2:33 pm

1 stop5h 33m

Des Moines

Thu 1/22

9:03 am-9:18 pm

2 stops11h 15m

$313

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 1/8

6:00 am-2:33 pm

2 stops9h 33m

Des Moines

Mon 1/12

3:35 pm-8:51 pm

1 stop4h 16m

$324

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 1/8

11:12 am-10:46 pm

2 stops12h 34m

Des Moines

Thu 1/15

4:30 pm-11:59 pm

2 stops30h 29m

$326

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 1/21

10:00 am-2:33 pm

1 stop5h 33m

Des Moines

Fri 1/23

11:30 am-5:04 pm

1 stop4h 34m

$329

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 12/30

7:00 am-11:10 pm

1 stop17h 10m

Des Moines

Mon 1/5

8:00 am-3:37 pm

2 stops54h 37m

$331

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 54 results
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $209). Flying from North Carolina to Des Moines in January is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s typically best to fly out from North Carolina to Des Moines in the evening. Doing so could potentially save you 14% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from North Carolina to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Des Moines flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 6h 28m. Delta provides one of the quickest options available for as low as $289. Airlines will cover a distance of 890 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $42 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $92 and $118, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Raleigh-Durham - Des Moines, Charlotte Douglas - Des Moines or Greensboro/H. Point - Des Moines as they are the most popular.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $209). Flying from North Carolina to Des Moines in January is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for North Carolina to Des Moines

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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$348FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$242Average$431FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$386FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$292Average$384FlexibilityNo cancel feeOn-time63%

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