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Des Moines

$89+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — DSM
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated August 20, 2025.

Round-trip from

$195
(Kiwi.com)

One-way from

$89
(FlightHub)

Popular in

May

Cheapest in

March

Average price

$421

Good round-trip deal

$406 or less
From North Carolina to Des Moines
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One-way flight from North Carolina to Des Moines
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Highest demand for flights based on searches. 4% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from North Carolina to Des Moines.
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Find flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:36 pmCLT - DSM
1 stop5h 32mMultiple Airlines
Sun 11/99:03 pmDSM - CLT
1 stop18h 24mMultiple Airlines
Deal found 8/17$195
This Mytrip deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/155:45 amCLT - DSM
1 stop9h 55mMultiple Airlines
Mon 9/228:25 amDSM - CLT
1 stop14h 11mMultiple Airlines
Deal found 8/18$208
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/269:10 amCLT - DSM
1 stop6h 30mMultiple Airlines
Mon 9/298:25 amDSM - CLT
1 stop29h 04mMultiple Airlines
Deal found 8/19$229
This Mytrip deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:08 pmILM - DSM
1 stop15h 22mMultiple Airlines
Sun 10/58:47 pmDSM - ILM
2 stops19h 10mMultiple Airlines
Deal found 8/20$230
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:10 amCLT - DSM
1 stop6h 40mMultiple Airlines
Sun 10/58:47 pmDSM - CLT
1 stop18h 00mMultiple Airlines
Deal found 8/19$235
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:49 pmRDU - DSM
1 stop18h 01mMultiple Airlines
Thu 10/910:51 amDSM - RDU
1 stop26h 29mMultiple Airlines
Deal found 8/18$245
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:59 pmAVL - DSM
1 stop5h 38mDelta
Sun 9/144:09 pmDSM - AVL
1 stop6h 29mDelta
Deal found 8/19$249
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:45 pmTYS - DSM
1 stop4h 21mAmerican Airlines
Mon 9/226:12 pmDSM - TYS
1 stop5h 09mAmerican Airlines
Deal found 8/18$249
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:49 pmRDU - DSM
1 stop18h 01mMultiple Airlines
Mon 10/138:30 amDSM - RDU
2 stops30h 07mMultiple Airlines
Deal found 8/18$253
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:17 amCLT - DSM
2 stops10h 40mMultiple Airlines
Mon 10/68:30 amDSM - CLT
1 stop28h 05mMultiple Airlines
Deal found 8/18$254
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/155:45 amTYS - DSM
2 stops9h 35mUnited Airlines
Mon 9/223:25 pmDSM - TYS
1 stop6h 20mUnited Airlines
Deal found 8/18$254
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:45 amTYS - DSM
2 stops9h 35mUnited Airlines
Wed 9/243:25 pmDSM - TYS
1 stop6h 20mUnited Airlines
Deal found 8/20$255

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

North Carolina

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 11/7

12:36 pm-5:08 pm

1 stop5h 32m

Des Moines

Sun 11/9

9:03 pm-4:27 pm

1 stop18h 24m

$195

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 9/15

5:45 am-2:40 pm

1 stop9h 55m

Des Moines

Mon 9/22

8:25 am-11:36 pm

1 stop14h 11m

$208

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 9/26

9:10 am-2:40 pm

1 stop6h 30m

Des Moines

Mon 9/29

8:25 am-2:29 pm

1 stop29h 04m

$229

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 10/10

8:52 am-2:50 pm

1 stop6h 58m

Des Moines

Mon 10/13

8:30 am-1:35 pm

1 stop28h 05m

$229

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Thu 10/2

6:08 pm-8:30 am

1 stop15h 22m

Des Moines

Sun 10/5

8:47 pm-4:57 pm

2 stops19h 10m

$230

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 10/3

9:10 am-2:50 pm

1 stop6h 40m

Des Moines

Sun 10/5

8:47 pm-3:47 pm

1 stop18h 00m

$235

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 10/2

9:49 pm-2:50 pm

1 stop18h 01m

Des Moines

Thu 10/9

10:51 am-2:20 pm

1 stop26h 29m

$245

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Fri 9/12

11:33 am-7:14 pm

1 stop8h 41m

Des Moines

Sun 9/14

6:30 pm-11:38 pm

1 stop4h 08m

$249

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Tue 9/16

10:54 am-2:20 pm

1 stop4h 26m

Des Moines

Tue 9/23

2:58 pm-11:44 pm

1 stop7h 46m

$249

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Mon 9/15

7:45 pm-11:06 pm

1 stop4h 21m

Des Moines

Mon 9/22

6:12 pm-12:21 am

1 stop5h 09m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, August is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $336). Flying from North Carolina to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Des Moines as you normally would.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 4h 21m. Delta provides one of the quickest options available for as low as $249. Airlines will cover a distance of 654 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $89 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $139 and $146, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Charlotte Douglas - Des Moines, Raleigh-Durham - Des Moines or Greensboro/H. Point - Des Moines as they are the most popular.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $336). Flying from North Carolina to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for North Carolina to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$358FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$434FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$417FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$296Average$376FlexibilityNo cancel feeOn-time63%

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