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Des Moines

$86+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — DSM
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/318:30 amTYS - DSM
1 stop5h 51mAmerican Airlines
dom. 1/46:26 pmDSM - TYS
1 stop4h 21mAmerican Airlines
Deal found 12/16$315
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:38 pmCLT - DSM
1 stop26h 32mMultiple Airlines
dom. 1/46:30 pmDSM - CLT
1 stop27h 59mMultiple Airlines
Deal found 12/14$353
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/307:20 pmRDU - DSM
1 stop19h 34mMultiple Airlines
lun. 1/58:00 amDSM - RDU
2 stops39h 12mMultiple Airlines
Deal found 12/15$358
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/307:05 amTYS - DSM
1 stop4h 33mDelta
sáb. 1/35:55 pmDSM - TYS
1 stop4h 18mDelta
Deal found 12/15$359
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/316:37 amRDU - DSM
1 stop6h 49mAmerican Airlines
dom. 1/46:26 pmDSM - RDU
1 stop4h 30mAmerican Airlines
Deal found 12/16$368
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:34 pmMYR - DSM
1 stop4h 47mAmerican Airlines
dom. 1/46:26 pmDSM - MYR
1 stop4h 29mAmerican Airlines
Deal found 12/16$368
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:01 amRDU - DSM
1 stop6h 48mAmerican Airlines
mié. 1/71:16 pmDSM - RDU
1 stop5h 36mAmerican Airlines
Deal found 12/15$369
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/239:24 amCLT - DSM
2 stops14h 46mMultiple Airlines
dom. 1/46:30 pmDSM - CLT
1 stop27h 59mMultiple Airlines
Deal found 12/14$412
This Frontier deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/2212:17 pmCLT - DSM
1 stop8h 27mFrontier
mar. 12/3011:14 amDSM - CLT
1 stop8h 15mFrontier
Deal found 12/14$422
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:30 amGSO - DSM
1 stop5h 20mUnited Airlines
sáb. 1/38:00 amDSM - GSO
1 stop7h 34mUnited Airlines
Deal found 12/14$439
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:31 amRDU - DSM
1 stop5h 19mUnited Airlines
mié. 1/78:00 amDSM - RDU
2 stops9h 52mUnited Airlines
Deal found 12/15$444
This Frontier deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1912:17 pmCLT - DSM
1 stop8h 27mFrontier
mar. 12/3011:14 amDSM - CLT
1 stop8h 15mFrontier
Deal found 12/14$452

Find flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$211
(Mytrip)

One-way from

$86
(Kiwi.com)

Popular in

February

Cheapest in

December

Average price

$333

Good round-trip deal

$397 or less
Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.
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From North Carolina to Des Moines
Search Deals
One-way flight from North Carolina to Des Moines
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from North Carolina to Des Moines.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

North Carolina

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jue. 1/8

9:06 am-10:46 pm

2 stops14h 40m

Des Moines

lun. 1/12

11:09 am-10:55 am

2 stops22h 46m

$237

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

jue. 1/15

3:08 pm-10:46 pm

1 stop8h 38m

Des Moines

lun. 1/19

8:18 pm-11:51 pm

2 stops26h 33m

$257

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

jue. 1/15

9:22 am-10:46 pm

2 stops14h 24m

Des Moines

jue. 1/22

2:58 pm-2:13 pm

1 stop22h 15m

$267

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jue. 1/15

1:24 pm-10:46 pm

1 stop10h 22m

Des Moines

lun. 1/19

11:09 am-10:55 am

2 stops22h 46m

$270

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

lun. 1/12

5:18 pm-9:50 pm

1 stop5h 32m

Des Moines

mié. 1/14

3:04 pm-10:30 pm

1 stop6h 26m

$292

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

mar. 1/6

10:00 am-2:33 pm

1 stop5h 33m

Des Moines

jue. 1/8

3:35 pm-9:18 pm

1 stop4h 43m

$292

NorfolkDes Moines

ORF - DSM

ORFDSM

Norfolk

mar. 1/20

5:35 am-9:41 am

1 stop5h 06m

Des Moines

sáb. 1/24

10:59 am-5:34 pm

1 stop5h 35m

$293

NorfolkDes Moines

ORF - DSM

ORFDSM

Norfolk

mar. 1/13

10:05 am-8:34 pm

2 stops11h 29m

Des Moines

mar. 1/20

1:35 pm-10:55 pm

1 stop8h 20m

$295

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

vie. 1/30

7:12 am-3:15 pm

1 stop9h 03m

Des Moines

lun. 2/2

1:16 pm-6:51 pm

1 stop4h 35m

$299

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

vie. 1/30

11:55 am-7:34 pm

1 stop8h 39m

Des Moines

lun. 2/2

5:16 pm-11:51 pm

1 stop5h 35m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $209). Flying from North Carolina to Des Moines in January is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

It’s typically best to fly out from North Carolina to Des Moines in the evening. Doing so could potentially save you 14% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from North Carolina to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to Des Moines flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 5h 06m. United Airlines provides one of the quickest options available for as low as $293. Airlines will cover a distance of 985 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $92 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $118 and $121, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Charlotte Douglas - Des Moines, Wilmington New Hanover County - Des Moines or Norfolk - Des Moines as they are the most popular.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $209). Flying from North Carolina to Des Moines in January is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for North Carolina to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Boston to Omaha flights
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O'Hare Intl to Des Moines flights
Los Angeles to Cedar Rapids flights
Orlando to Des Moines flights
Hobby to Moline flights
Detroit to Omaha flights
Ontario to Cedar Rapids flights
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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$242Average$384FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$386FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$292Average$384FlexibilityNo cancel feeOn-time63%

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