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Des Moines

$96+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — DSM
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Sun 4/198:30 am
DSM
-
CLT
1 stop23h 40m
Multiple Airlines
Deal found 3/14$236
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Sun 4/268:30 am
DSM
-
CLT
1 stop23h 40m
Multiple Airlines
Deal found 3/12$250
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:54 pm
CLT
-
DSM
1 stop19h 06m
Multiple Airlines
Mon 4/202:04 pm
DSM
-
CLT
2 stops19h 13m
Multiple Airlines
Deal found 3/15$254
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:46 pm
RDU
-
DSM
1 stop27h 20m
Multiple Airlines
Mon 4/139:07 pm
DSM
-
RDU
2 stops20h 37m
Multiple Airlines
Deal found 3/12$255
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Mon 4/202:04 pm
DSM
-
CLT
2 stops19h 13m
Multiple Airlines
Deal found 3/15$259
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:28 am
CLT
-
DSM
1 stop9h 47m
Multiple Airlines
Sun 5/107:45 am
DSM
-
CLT
1 stop11h 34m
Multiple Airlines
Deal found 3/14$268
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:05 am
RDU
-
DSM
1 stop16h 53m
Multiple Airlines
Mon 6/84:07 pm
DSM
-
RDU
1 stop28h 46m
Multiple Airlines
Deal found 3/14$270
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:45 pm
RDU
-
DSM
2 stops9h 25m
Southwest
Tue 5/195:30 am
DSM
-
RDU
1 stop4h 00m
Southwest
Deal found 3/16$276
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:00 pm
CLT
-
DSM
1 stop26h 06m
Multiple Airlines
Mon 4/139:07 pm
DSM
-
CLT
2 stops23h 56m
Multiple Airlines
Deal found 3/15$278
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:00 pm
RDU
-
DSM
1 stop7h 32m
United Airlines
Mon 4/133:21 pm
DSM
-
RDU
1 stop5h 02m
United Airlines
Deal found 3/12$279
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Thu 4/237:00 am
DSM
-
CLT
1 stop27h 20m
Multiple Airlines
Deal found 3/17$280
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:33 pm
AVL
-
DSM
1 stop21h 42m
Allegiant Air
Sun 5/107:45 am
DSM
-
AVL
1 stop14h 31m
Allegiant Air
Deal found 3/13$282

Find flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$236
(Kiwi.com)

One-way from

$96
(Kiwi.com)

Popular in

February

Cheapest in

December

Average price

$441

Good round-trip deal

$405 or less
Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.
Search Deals
From North Carolina to Des Moines
Search Deals
One-way flight from North Carolina to Des Moines
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 5/13

1:45 pm-10:10 pm

2 stops9h 25m

Des Moines

Tue 5/19

5:30 am-10:30 am

1 stop4h 00m

$276

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 4/8

3:00 pm-9:32 pm

1 stop7h 32m

Des Moines

Mon 4/13

3:21 pm-9:23 pm

1 stop5h 02m

$279

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 5/12

1:25 pm-9:15 pm

2 stops8h 50m

Des Moines

Sat 5/16

5:35 am-3:15 pm

2 stops8h 40m

$299

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Mon 6/1

1:36 pm-11:24 pm

1 stop10h 48m

Des Moines

Fri 6/5

6:00 am-10:40 pm

1 stop15h 40m

$304

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Thu 4/16

1:56 pm-8:21 pm

1 stop7h 25m

Des Moines

Mon 4/20

2:16 pm-10:08 pm

1 stop6h 52m

$309
Quickest round-trip

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Thu 5/7

6:45 am-10:37 am

1 stop4h 52m

Des Moines

Sun 5/10

8:00 am-1:27 pm

1 stop4h 27m

$309

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 4/9

4:48 pm-11:59 pm

1 stop8h 11m

Des Moines

Mon 4/13

5:01 pm-10:31 pm

1 stop4h 30m

$309

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 5/13

1:45 pm-10:10 pm

2 stops9h 25m

Des Moines

Wed 5/20

5:30 am-10:30 am

1 stop4h 00m

$312

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Wed 5/6

7:23 pm-11:49 pm

1 stop5h 26m

Des Moines

Sat 5/9

11:09 am-7:39 pm

2 stops7h 30m

$314

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Fri 4/17

4:46 pm-9:53 pm

1 stop6h 07m

Des Moines

Mon 4/20

2:16 pm-11:50 pm

2 stops8h 34m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $212). Flying from North Carolina to Des Moines in February is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 18, 2026.

It’s typically best to fly out from North Carolina to Des Moines in the morning. Doing so could potentially save you 18% on the flight price compared to flying in the evening, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 7h 32m. Southwest provides one of the quickest options available for as low as $279. Airlines will cover a distance of 890 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $78 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $92 and $118, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Charlotte Douglas - Des Moines, Asheville Regional - Des Moines or Raleigh-Durham - Des Moines as they are the most popular.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $212). Flying from North Carolina to Des Moines in February is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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Alternative routes for North Carolina to Des Moines

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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$201Average$371FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$242Average$365FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$369FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$335Average$396FlexibilityNo cancel feeOn-time63%

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