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Des Moines

$100+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — DSM
Apr 10 — Apr 171
Fri 4/10
Fri 4/17
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Mon 4/202:04 pm
DSM
-
CLT
1 stop27h 50m
Multiple Airlines
Deal found 3/10$245
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:29 am
RDU
-
DSM
1 stop11h 58m
Multiple Airlines
Mon 6/156:44 pm
DSM
-
RDU
1 stop26h 09m
Multiple Airlines
Deal found 3/7$248
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:46 pm
RDU
-
DSM
1 stop27h 20m
Multiple Airlines
Mon 4/138:14 pm
DSM
-
RDU
1 stop20h 48m
Multiple Airlines
Deal found 3/9$259
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:30 am
RDU
-
DSM
1 stop6h 48m
Multiple Airlines
Mon 6/86:00 am
DSM
-
RDU
2 stops14h 21m
Multiple Airlines
Deal found 3/9$267
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:46 pm
RDU
-
DSM
1 stop27h 20m
Multiple Airlines
Mon 4/202:04 pm
DSM
-
RDU
2 stops25h 52m
Multiple Airlines
Deal found 3/7$271
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
AVL
-
DSM
1 stop17h 06m
Allegiant Air
Mon 4/132:03 pm
DSM
-
AVL
1 stop8h 12m
Allegiant Air
Deal found 3/8$278
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
RDU
-
DSM
2 stops17h 06m
Multiple Airlines
Fri 4/242:04 pm
DSM
-
RDU
1 stop30h 00m
Multiple Airlines
Deal found 3/7$279
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:46 pm
RDU
-
DSM
1 stop18h 43m
Multiple Airlines
Sat 3/286:56 pm
DSM
-
RDU
1 stop12h 51m
Multiple Airlines
Deal found 3/10$281
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Sun 4/268:30 am
DSM
-
CLT
1 stop23h 40m
Multiple Airlines
Deal found 3/7$282
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
RDU
-
DSM
2 stops14h 14m
Frontier
Fri 4/242:04 pm
DSM
-
RDU
1 stop30h 00m
Frontier
Deal found 3/7$282
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:54 pm
CLT
-
DSM
1 stop25h 12m
Multiple Airlines
Mon 5/48:23 pm
DSM
-
CLT
1 stop21h 31m
Multiple Airlines
Deal found 3/9$284
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:56 am
CLT
-
DSM
1 stop8h 04m
Multiple Airlines
Mon 4/272:04 pm
DSM
-
CLT
2 stops19h 13m
Multiple Airlines
Deal found 3/8$287

Find flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated March 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$245
(Kiwi.com)

One-way from

$100
(Kiwi.com)

Popular in

February

Cheapest in

December

Average price

$420

Good round-trip deal

$405 or less

Good one-way deal

$420 or less
Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.
Search Deals
From North Carolina to Des Moines
Search Deals
One-way flight from North Carolina to Des Moines
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Des Moines.
Search Deals
Price to beat on a one-way flight from North Carolina to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Thu 4/16

6:06 pm-10:34 pm

1 stop5h 28m

Des Moines

Mon 4/20

2:44 pm-8:41 pm

1 stop4h 57m

$289

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Thu 4/16

7:23 pm-11:49 pm

1 stop5h 26m

Des Moines

Mon 4/20

3:20 pm-10:43 pm

1 stop6h 23m

$289

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Thu 5/7

12:22 pm-7:34 pm

1 stop8h 12m

Des Moines

Sun 5/10

9:00 am-6:43 pm

1 stop8h 43m

$289

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 4/2

7:10 am-1:07 pm

1 stop6h 57m

Des Moines

Sun 4/5

5:00 am-11:14 am

1 stop5h 14m

$289

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 4/9

2:06 pm-7:27 pm

1 stop6h 21m

Des Moines

Mon 4/13

6:31 pm-11:55 pm

1 stop4h 24m

$289

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 4/15

4:45 pm-10:43 pm

1 stop6h 58m

Des Moines

Mon 4/20

3:21 pm-11:44 pm

2 stops7h 23m

$292

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Thu 5/7

6:00 am-11:30 am

1 stop6h 30m

Des Moines

Sun 5/10

6:00 am-2:13 pm

2 stops7h 13m

$294

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Fri 4/17

5:22 pm-11:59 pm

1 stop7h 37m

Des Moines

Mon 4/20

2:16 pm-11:50 pm

2 stops8h 34m

$294

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Tue 3/24

4:04 pm-11:42 pm

1 stop8h 38m

Des Moines

Sat 3/28

3:28 pm-8:47 pm

1 stop4h 19m

$299

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/21

6:40 am-11:08 am

1 stop5h 28m

Des Moines

Sat 5/30

6:41 pm-11:57 pm

1 stop4h 16m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $209). Flying from North Carolina to Des Moines in February is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 11, 2026.

It’s typically best to fly out from North Carolina to Des Moines in the morning. Doing so could potentially save you 15% on the flight price compared to flying in the evening, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 5h 28m. Delta provides one of the quickest options available for as low as $289. Airlines will cover a distance of 733 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $78 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $92 and $118, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Charlotte Douglas - Des Moines, Asheville Regional - Des Moines or Raleigh-Durham - Des Moines as they are the most popular.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $209). Flying from North Carolina to Des Moines in February is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$242Average$364FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$371FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$369FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$292Average$396FlexibilityNo cancel feeOn-time63%

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