$82+ Cheap flights from Chicago (CHI) to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — DSM
Jun 7 — Jun 141
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to Des Moines
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Cheapest flights from Chicago to Des MoinesExplore the most affordable flight options available from Chicago to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.
Explore the most affordable flight options available from Chicago to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:37 pm
ORD
- DSM
1 stop15h 54m
Frontier
Mon 6/12:16 pm
DSM
- ORD
1 stop6h 16m
Frontier
Deal found 5/5![Frontier logo]()
$230
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:40 am
ORD
- DSM
Nonstop1h 33m
American Airlines
Tue 5/267:10 pm
DSM
- ORD
Nonstop2h 00m
American Airlines
Deal found 5/4![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:00 am
MDW
- DSM
Nonstop1h 25m
Southwest
Tue 6/165:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/3![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
ORD
- DSM
Nonstop1h 35m
United Airlines
Thu 5/286:00 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/4![United Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:42 am
ORD
- DSM
1 stop3h 42m
Delta
Tue 6/166:08 am
DSM
- ORD
1 stop4h 42m
Delta
Deal found 5/3![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Wed 6/245:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/6![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:31 pm
ORD
- DSM
Nonstop1h 37m
American Airlines
Thu 5/288:43 am
DSM
- ORD
Nonstop1h 49m
American Airlines
Deal found 5/6![American Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Tue 6/95:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/7![Southwest logo]()
$263
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:00 pm
ORD
- DSM
Nonstop1h 35m
American Airlines
Sat 6/69:23 am
DSM
- ORD
Nonstop1h 42m
American Airlines
Deal found 5/4![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:20 am
MDW
- DSM
Nonstop1h 25m
Southwest
Mon 6/15:25 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/7![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:00 pm
ORD
- DSM
1 stop6h 36m
Delta
Wed 6/106:08 am
DSM
- ORD
1 stop6h 56m
Delta
Deal found 5/4![Delta logo]()
$273
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 am
ORD
- DSM
1 stop3h 44m
Delta
Tue 6/232:45 pm
DSM
- ORD
1 stop6h 40m
Delta
Deal found 5/5![Delta logo]()
$277
Best flights from Chicago to Des MoinesDiscover carefully curated flight deals from Chicago to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 8, 2026.
Discover carefully curated flight deals from Chicago to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 8, 2026.
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:55 am
ORD
- DSM
Nonstop1h 35m
United Airlines
Thu 6/46:00 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/4![United Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Wed 6/245:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/6![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:54 am
MDW
- DSM
1 stop4h 11m
Delta
Wed 6/246:08 am
DSM
- MDW
1 stop6h 38m
Delta
Deal found 5/6![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:31 pm
ORD
- DSM
Nonstop1h 37m
American Airlines
Sun 5/317:10 pm
DSM
- ORD
Nonstop2h 00m
American Airlines
Deal found 5/2![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 6/45:10 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/4![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:36 pm
ORD
- DSM
Nonstop1h 33m
United Airlines
Mon 6/86:00 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/3![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:24 am
ORD
- DSM
1 stop6h 00m
Delta
Fri 5/1510:26 am
DSM
- ORD
1 stop6h 03m
Delta
Deal found 5/5![Delta logo]()
$345
This KAYAK deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:45 pm
ORD
- DSM
1 stop7h 32m
American Airlines
Thu 6/47:09 pm
DSM
- ORD
Nonstop1h 57m
American Airlines
Deal found 5/7![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:50 am
MDW
- DSM
Nonstop1h 30m
Southwest
Sun 10/255:35 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/7![Southwest logo]()
$329
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:24 am
ORD
- DSM
1 stop3h 52m
Delta
Tue 6/3010:54 am
DSM
- ORD
1 stop4h 11m
Delta
Deal found 5/4![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:05 am
MDW
- DSM
Nonstop1h 20m
Southwest
Sun 9/67:05 am
DSM
- MDW
1 stop7h 30m
Southwest
Deal found 5/6![Southwest logo]()
$339
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:30 am
ORD
- DSM
1 stop3h 44m
Delta
Mon 6/152:45 pm
DSM
- ORD
1 stop6h 40m
Delta
Deal found 5/5![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Sat 6/63:35 pm
DSM
- MDW
Nonstop1h 25m
Southwest
Deal found 5/3![Southwest logo]()
$343
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:27 am
ORD
- DSM
1 stop5h 38m
Delta
Sun 7/126:00 am
DSM
- ORD
1 stop7h 03m
Delta
Deal found 5/2![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Thu 6/41:30 pm
DSM
- MDW
2 stops7h 10m
Southwest
Deal found 5/3![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:24 am
ORD
- DSM
1 stop3h 52m
Delta
Thu 6/112:45 pm
DSM
- ORD
1 stop6h 40m
Delta
Deal found 5/7![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:35 pm
MDW
- DSM
1 stop8h 40m
Southwest
Thu 5/285:25 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/7![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Sun 8/26:10 pm
DSM
- MDW
1 stop6h 05m
Southwest
Deal found 5/4![Southwest logo]()
$363
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:41 pm
ORD
- DSM
1 stop3h 31m
Delta
Thu 6/46:15 am
DSM
- ORD
1 stop4h 14m
Delta
Deal found 5/3![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:41 pm
ORD
- DSM
1 stop3h 31m
Delta
Sat 5/166:15 am
DSM
- ORD
1 stop4h 14m
Delta
Deal found 5/5![Delta logo]()
$445
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:24 am
ORD
- DSM
1 stop3h 52m
Delta
Sat 5/1610:56 am
DSM
- ORD
1 stop4h 01m
Delta
Deal found 5/5![Delta logo]()
$445
Last-minute flights from Chicago to Des MoinesDiscover last-minute flight deals from Chicago to Des Moines. Data last updated May 8, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Des Moines. Data last updated May 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:40 am
ORD
- DSM
Nonstop1h 33m
American Airlines
Tue 5/267:10 pm
DSM
- ORD
Nonstop2h 00m
American Airlines
Deal found 5/4![American Airlines logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
ORD
- DSM
Nonstop1h 35m
United Airlines
Thu 5/286:00 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/4![United Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:31 pm
ORD
- DSM
Nonstop1h 37m
American Airlines
Thu 5/288:43 am
DSM
- ORD
Nonstop1h 49m
American Airlines
Deal found 5/6![American Airlines logo]()
$263
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:37 pm
ORD
- DSM
1 stop15h 54m
Frontier
Mon 6/12:16 pm
DSM
- ORD
1 stop6h 16m
Frontier
Deal found 5/5![Frontier logo]()
$230
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:20 am
MDW
- DSM
Nonstop1h 25m
Southwest
Mon 6/15:25 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/7![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:00 am
MDW
- DSM
Nonstop1h 25m
Southwest
Tue 6/165:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/3![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:42 am
ORD
- DSM
1 stop3h 42m
Delta
Tue 6/166:08 am
DSM
- ORD
1 stop4h 42m
Delta
Deal found 5/3![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:00 pm
ORD
- DSM
Nonstop1h 35m
American Airlines
Sat 6/69:23 am
DSM
- ORD
Nonstop1h 42m
American Airlines
Deal found 5/4![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:00 pm
ORD
- DSM
1 stop6h 36m
Delta
Wed 6/106:08 am
DSM
- ORD
1 stop6h 56m
Delta
Deal found 5/4![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Tue 6/95:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/7![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 am
ORD
- DSM
1 stop3h 44m
Delta
Tue 6/232:45 pm
DSM
- ORD
1 stop6h 40m
Delta
Deal found 5/5![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Wed 6/245:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 5/6![Southwest logo]()
$257
One-way flights from Chicago to Des MoinesSearch for one-way flight options from Chicago to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 8, 2026.
Search for one-way flight options from Chicago to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:37 pm
ORD
- DSM
1 stop15h 54m
Frontier
Deal found 5/4![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:52 pm
ORD
- DSM
1 stop26h 39m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:00 pm
ORD
- DSM
1 stop26h 52m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:29 pm
ORD
- DSM
2 stops33h 29m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$116
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:29 am
ORD
- DSM
Nonstop1h 33m
American Airlines
Deal found 5/4![American Airlines logo]()
$119
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 5/4![Southwest logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:29 pm
ORD
- DSM
2 stops33h 29m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
MDW
- DSM
2 stops16h 58m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:37 pm
ORD
- DSM
1 stop15h 54m
Frontier
Deal found 5/7![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:05 am
ORD
- DSM
2 stops37h 22m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:15 am
ORD
- DSM
1 stop29h 44m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:55 am
ORD
- DSM
2 stops16h 03m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$125
Find flight deals from Chicago to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Frontier) |
One-way from | $82 (Kiwi.com) |
Popular in | April |
Cheapest in | October |
Average price | $392 |
Good round-trip deal | $329 or less |
Good one-way deal | $164 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Chicago to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Tue 6/2
8:55 am-10:30 am
Nonstop1h 35m
Des Moines
Thu 6/4
6:00 am-7:40 am
Nonstop1h 40m
$253
Quickest round-trip
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Wed 6/17
10:10 am-11:30 am
Nonstop1h 20m
Des Moines
Wed 6/24
5:20 am-6:40 am
Nonstop1h 20m
$257
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Wed 6/17
9:54 am-2:05 pm
1 stop4h 11m
Des Moines
Wed 6/24
6:08 am-12:46 pm
1 stop6h 38m
$277
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Thu 5/28
10:31 pm-12:08 am
Nonstop1h 37m
Des Moines
Sun 5/31
7:10 pm-9:10 pm
Nonstop2h 00m
$313
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Tue 6/2
8:50 pm-10:10 pm
Nonstop1h 20m
Des Moines
Thu 6/4
5:10 am-6:30 am
Nonstop1h 20m
$319
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Fri 10/23
9:50 am-11:20 am
Nonstop1h 30m
Des Moines
Sun 10/25
5:35 am-6:55 am
Nonstop1h 20m
$329
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Thu 6/4
4:36 pm-6:09 pm
Nonstop1h 33m
Des Moines
Mon 6/8
6:00 am-7:40 am
Nonstop1h 40m
$339
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Fri 9/4
10:05 am-11:25 am
Nonstop1h 20m
Des Moines
Sun 9/6
7:05 am-2:35 pm
1 stop7h 30m
$339
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Thu 6/4
10:05 pm-11:30 pm
Nonstop1h 25m
Des Moines
Sat 6/6
3:35 pm-5:00 pm
Nonstop1h 25m
$343
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Sun 5/10
6:24 am-12:24 pm
1 stop6h 00m
Des Moines
Fri 5/15
10:26 am-4:29 pm
1 stop6h 03m
$345
Showing 1-10 of 43 resultsSorted by cheapest first
Compare providers for flights from Chicago to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Des Moines in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Chicago with our price prediction graph.
CHI-DSM
MDW-DSM
ORD-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Des Moines
CHI-DSM
MDW-DSM
ORD-DSM
What is the cheapest month to book a flight from Chicago to Des Moines?
Currently, February is the cheapest month in which you can book a flight from Chicago to Des Moines (average of $126). Flying from Chicago to Des Moines in December is currently the most expensive (average of $192). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to DSM?
Find hourly flight availability from Chicago to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 8, 2026.
It’s optimal to fly from Chicago to Des Moines at noon. By choosing this option you can save up to 42% on the cost of your flight, compared to a flight in the evening.
What is the cheapest day to fly from Chicago to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Des Moines. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Chicago to Des Moines flight should consider departing on Thursday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago to Des Moines
Explore weekly flight availability from Chicago to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 8, 2026.
The most flights from CHI to DSM are scheduled on a Thursday (51 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (33 on average).
How much does it cost to fly round-trip from Chicago to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated May 8, 2026.
See what other customers who have flown with United Airlines and American Airlines from Chicago to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Overall
7.4
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Overall
7.4
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from Chicago to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Chicago and Des Moines flights
Browse other Chicago and Des Moines flight options. Last updated on May 8, 2026.
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Top 2 airlines flying from Chicago to Des Moines
Discover the top 2 airlines that operate flights from Chicago to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$257 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$364 | FlexibilityNo cancel fee | On-time69% |