
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (American Airlines) |
One-way from | $56 (Southwest) |
Popular in | December |
Cheapest in | March |
Average price | $243 |
Good round-trip deal | $240 or less |
Good one-way deal | $113 or less |
Fly from
Fly to
Route
Depart
Return
Price
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Wed 4/8
9:56 am-11:30 am
Nonstop1h 34m
Des Moines
Sat 4/11
6:00 am-7:41 am
Nonstop1h 41m
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Wed 4/8
1:10 pm-4:54 pm
1 stop3h 44m
Des Moines
Sat 4/11
12:29 pm-5:54 pm
1 stop5h 25m
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Thu 3/26
10:18 pm-11:40 pm
Nonstop1h 22m
Des Moines
Sat 3/28
10:04 am-11:37 am
Nonstop1h 33m
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Fri 4/10
12:49 pm-2:15 pm
Nonstop1h 26m
Des Moines
Sun 4/12
3:21 pm-4:53 pm
Nonstop1h 32m
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Sun 3/29
12:59 pm-2:25 pm
Nonstop1h 26m
Des Moines
Fri 4/3
8:04 am-9:36 am
Nonstop1h 32m
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Fri 4/3
7:25 am-8:49 am
Nonstop1h 24m
Des Moines
Sun 4/5
5:00 am-6:29 am
Nonstop1h 29m
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Thu 3/5
9:50 pm-11:15 pm
Nonstop1h 25m
Des Moines
Sun 3/8
4:40 pm-6:00 pm
Nonstop1h 20m
ChicagoDes Moines
MDW - DSM
MDWDSM
Chicago Midway
Sun 3/29
10:10 pm-11:35 pm
Nonstop1h 25m
Des Moines
Fri 4/3
5:35 am-6:55 am
Nonstop1h 20m
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Sat 2/21
4:20 pm-5:47 pm
Nonstop1h 27m
Des Moines
Sat 2/28
3:24 pm-5:00 pm
Nonstop1h 36m
ChicagoDes Moines
ORD - DSM
ORDDSM
Chicago O'Hare Intl
Thu 2/26
10:18 pm-11:40 pm
Nonstop1h 22m
Des Moines
Sun 3/1
6:32 am-8:05 am
Nonstop1h 33m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
Currently, February is the cheapest month in which you can book a flight from Chicago to Des Moines (average of $171). Flying from Chicago to Des Moines in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s optimal to fly from Chicago to Des Moines at noon. By choosing this option you can save up to 38% on the cost of your flight, compared to a flight in the morning.
Travelers seeking maximum savings on their Chicago to Des Moines flight should consider departing on Thursday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
The most flights from CHI to DSM are scheduled on a Tuesday (33 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (19 on average).
Food
Entertainment
Crew
Overall
Comfort
Boarding
Reviews
Dane,Jan 2026
TYS - IAD
Food
Entertainment
Crew
Overall
Comfort
Boarding
Reviews
Dane,Jan 2026
TYS - IAD
Food
Entertainment
Crew
Overall
Comfort
Boarding
Reviews
Dane,Jan 2026
TYS - IAD
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$269 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$291 | FlexibilityNo cancel fee | On-time69% |