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$141+ Cheap flights from Knoxville to Charleston (TYS - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Knoxville to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$297
(Delta)

One-way from

$141
(Mytrip)

Popular in

December

Cheapest in

May

Average price

$468
From Knoxville McGhee Tyson to Charleston
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One-way flight from Knoxville McGhee Tyson to Charleston
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Highest demand for flights based on searches. 17% potential increase in price ($92 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Charleston

Cheapest flights from Knoxville to Charleston
Explore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/267:10 amTYS - CHS
1 stop4h 40mDelta
Sun 8/318:05 amCHS - TYS
1 stop5h 03mDelta
Deal found 7/1$297
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:26 pmTYS - CHS
2 stops19h 41mMultiple Airlines
Thu 10/169:38 pmCHS - TYS
2 stops22h 26mMultiple Airlines
Deal found 7/2$301
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/111:12 pmTYS - CHS
2 stops18h 54mAllegiant Air
Mon 7/146:41 pmCHS - TYS
2 stops18h 30mAllegiant Air
Deal found 6/30$315
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:58 pmTYS - CHS
1 stop4h 16mAmerican Airlines
Sat 7/265:00 amCHS - TYS
1 stop3h 34mAmerican Airlines
Deal found 7/2$327
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:45 amTYS - CHS
2 stops13h 23mUnited Airlines
Sat 9/207:45 pmCHS - TYS
1 stop14h 43mUnited Airlines
Deal found 7/2$474

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Knoxville to Charleston that are best for you.

Fly from

Knoxville

Fly to

Charleston

Route

Depart

Return

Price

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Tue 8/26

7:10 am-11:50 am

1 stop4h 40m

Charleston

Sun 8/31

8:05 am-1:08 pm

1 stop5h 03m

$297

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sat 10/11

4:26 pm-12:07 pm

2 stops19h 41m

Charleston

Thu 10/16

9:38 pm-8:04 pm

2 stops22h 26m

$301

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Wed 7/23

5:58 pm-10:14 pm

1 stop4h 16m

Charleston

Sat 7/26

5:00 am-8:34 am

1 stop3h 34m

$327

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sat 9/13

5:45 am-7:08 pm

2 stops13h 23m

Charleston

Sat 9/20

7:45 pm-10:28 am

1 stop14h 43m

$474

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Thu 7/17

8:54 pm-1:27 pm

2 stops16h 33m

$141

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Fri 7/11

1:12 pm-8:06 am

2 stops18h 54m

$150

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Wed 7/23

5:30 am-9:37 am

1 stop4h 07m

$217

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

Sun 7/13

5:58 pm-11:59 pm

1 stop6h 01m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Best time to book a flight from Knoxville to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Charleston

What is the cheapest month to book a flight from Knoxville to Charleston?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Charleston (average of $217). Flying from Knoxville to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CHS?

Find hourly flight availability from Knoxville to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from Knoxville to Charleston, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 19% versus a flight in the afternoon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and Allegiant Air from Knoxville to Charleston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
708 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Charleston round-trip?

    Currently priced at $297, Delta will fly you from Knoxville to Charleston and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $327 and $474, respectively. You may be able to fly from Knoxville to Charleston for 33% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Knoxville to Charleston one-way?

    One-way options have recently been found by users for as low as $150 on Allegiant Air. Other airlines that offer cheap prices include Delta from $217 and American Airlines from $339 one-way.

  • Can I find deals for flights from Knoxville to Charleston that include hotel bookings?

    Yes. In addition to deals on Knoxville to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Charleston.

  • Can I find deals for business class flights from Knoxville to Charleston?

    Yes. Cheapflights offers flight deals from Knoxville to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Charleston (average of $217). Flying from Knoxville to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Folly Beach
Santee
Edisto Beach

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Top 2 airlines flying from Knoxville to Charleston

Discover the top 2 airlines that operate flights from Knoxville to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$320Average$498FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$356Average$478FlexibilityNo cancel feeOn-time71%

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