$118+ Cheap flights from Knoxville to Charleston (TYS - CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
Jun 3 — Jun 101
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Charleston
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to CharlestonExplore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
Explore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:03 pm
TYS
- CHS
1 stop10h 45m
Multiple Airlines
Mon 5/253:23 pm
CHS
- TYS
1 stop24h 47m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
- CHS
1 stop10h 35m
Multiple Airlines
Thu 6/258:20 pm
CHS
- TYS
1 stop26h 52m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:29 pm
TYS
- CHS
1 stop14h 19m
Multiple Airlines
Tue 8/1111:15 am
CHS
- TYS
1 stop24h 51m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:24 pm
TYS
- CHS
1 stop14h 34m
Multiple Airlines
Mon 6/83:23 pm
CHS
- TYS
1 stop8h 16m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:05 pm
TYS
- CHS
1 stop23h 59m
Multiple Airlines
Wed 7/228:56 pm
CHS
- TYS
2 stops39h 50m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 am
TYS
- CHS
1 stop5h 07m
American Airlines
Sat 6/67:50 pm
CHS
- TYS
1 stop3h 57m
American Airlines
Deal found 5/3![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:15 am
TYS
- CHS
1 stop5h 20m
Southwest
Sat 6/66:30 am
CHS
- TYS
2 stops7h 35m
Southwest
Deal found 5/3![Southwest logo]()
$294
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 am
TYS
- CHS
1 stop3h 03m
Delta
Thu 6/46:15 am
CHS
- TYS
1 stop3h 19m
Delta
Deal found 4/30![Delta logo]()
$299
Best flights from Knoxville to CharlestonDiscover carefully curated flight deals from Knoxville to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
Discover carefully curated flight deals from Knoxville to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:24 pm
TYS
- CHS
1 stop14h 34m
Multiple Airlines
Mon 6/83:23 pm
CHS
- TYS
1 stop8h 16m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:15 am
TYS
- CHS
1 stop5h 20m
Southwest
Sat 6/66:30 am
CHS
- TYS
2 stops7h 35m
Southwest
Deal found 5/3![Southwest logo]()
$294
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 am
TYS
- CHS
1 stop3h 03m
Delta
Thu 6/46:15 am
CHS
- TYS
1 stop3h 19m
Delta
Deal found 4/30![Delta logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
- CHS
1 stop10h 35m
Multiple Airlines
Thu 6/258:33 pm
CHS
- TYS
2 stops24h 40m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:10 am
TYS
- CHS
1 stop5h 20m
Southwest
Fri 7/34:10 pm
CHS
- TYS
1 stop6h 20m
Southwest
Deal found 4/29![Southwest logo]()
$308
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 am
TYS
- CHS
1 stop4h 38m
Delta
Sun 6/217:59 pm
CHS
- TYS
1 stop3h 55m
Delta
Deal found 4/30![Delta logo]()
$308
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:05 am
TYS
- CHS
2 stops10h 15m
Southwest
Mon 6/84:10 pm
CHS
- TYS
1 stop6h 20m
Southwest
Deal found 5/4![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1911:55 am
TYS
- CHS
1 stop4h 03m
Delta
Sun 6/217:59 pm
CHS
- TYS
1 stop3h 55m
Delta
Deal found 4/30![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:35 am
TYS
- CHS
2 stops12h 45m
Southwest
Thu 6/44:10 pm
CHS
- TYS
1 stop6h 20m
Southwest
Deal found 4/30![Southwest logo]()
$329
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:10 am
TYS
- CHS
1 stop6h 00m
Southwest
Wed 7/222:10 pm
CHS
- TYS
1 stop6h 10m
Southwest
Deal found 4/30![Southwest logo]()
$337
Last-minute flights from Knoxville to CharlestonDiscover last-minute flight deals from Knoxville to Charleston. Data last updated May 4, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Charleston. Data last updated May 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:03 pm
TYS
- CHS
1 stop10h 45m
Multiple Airlines
Mon 5/253:23 pm
CHS
- TYS
1 stop24h 47m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 am
TYS
- CHS
1 stop3h 03m
Delta
Thu 6/46:15 am
CHS
- TYS
1 stop3h 19m
Delta
Deal found 4/30![Delta logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:24 pm
TYS
- CHS
1 stop14h 34m
Multiple Airlines
Mon 6/83:23 pm
CHS
- TYS
1 stop8h 16m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 am
TYS
- CHS
1 stop5h 07m
American Airlines
Sat 6/67:50 pm
CHS
- TYS
1 stop3h 57m
American Airlines
Deal found 5/3![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:15 am
TYS
- CHS
1 stop5h 20m
Southwest
Sat 6/66:30 am
CHS
- TYS
2 stops7h 35m
Southwest
Deal found 5/3![Southwest logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:10 am
TYS
- CHS
1 stop7h 41m
Multiple Airlines
Sat 6/133:44 pm
CHS
- TYS
2 stops45h 02m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:40 am
TYS
- CHS
1 stop4h 38m
Delta
Sun 6/217:59 pm
CHS
- TYS
1 stop3h 55m
Delta
Deal found 4/30![Delta logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
- CHS
1 stop10h 35m
Multiple Airlines
Thu 6/258:20 pm
CHS
- TYS
1 stop26h 52m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$255
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:10 am
TYS
- CHS
2 stops12h 15m
Southwest
Fri 7/34:10 pm
CHS
- TYS
1 stop6h 20m
Southwest
Deal found 4/29![Southwest logo]()
$313
One-way flights from Knoxville to CharlestonSearch for one-way flight options from Knoxville to Charleston. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
Search for one-way flight options from Knoxville to Charleston. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:03 pm
TYS
- CHS
1 stop10h 45m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
TYS
- CHS
2 stops24h 48m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$130
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:40 am
TYS
- CHS
1 stop4h 20m
Delta
Deal found 5/1![Delta logo]()
$140
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:10 am
TYS
- CHS
2 stops12h 15m
Southwest
Deal found 5/1![Southwest logo]()
$145
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:59 pm
TYS
- CHS
1 stop4h 00m
American Airlines
Deal found 4/30![American Airlines logo]()
$150
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:40 am
TYS
- CHS
2 stops14h 20m
Southwest
Deal found 4/30![Southwest logo]()
$161
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:00 am
TYS
- CHS
1 stop5h 25m
Southwest
Deal found 5/2![Southwest logo]()
$169
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:30 am
TYS
- CHS
2 stops8h 05m
Southwest
Deal found 4/29![Southwest logo]()
$174
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:40 am
TYS
- CHS
2 stops12h 15m
Southwest
Deal found 5/4![Southwest logo]()
$180
Find flight deals from Knoxville to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $238 (Kiwi.com) |
One-way from | $118 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $488 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Knoxville to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Mon 6/1
7:24 pm-9:58 am
1 stop14h 34m
Charleston
Mon 6/8
3:23 pm-11:39 pm
1 stop8h 16m
$277
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Tue 6/2
8:15 am-1:35 pm
1 stop5h 20m
Charleston
Sat 6/6
6:30 am-2:05 pm
2 stops7h 35m
$294
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Mon 6/22
10:03 pm-8:38 am
1 stop10h 35m
Charleston
Thu 6/25
8:33 pm-9:13 pm
2 stops24h 40m
$297
Quickest round-trip
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Thu 5/28
5:40 am-8:43 am
1 stop3h 03m
Charleston
Thu 6/4
6:15 am-9:34 am
1 stop3h 19m
$299
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Tue 6/30
8:10 am-1:30 pm
1 stop5h 20m
Charleston
Fri 7/3
4:10 pm-10:30 pm
1 stop6h 20m
$308
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Wed 6/17
5:40 am-10:18 am
1 stop4h 38m
Charleston
Sun 6/21
7:59 pm-11:54 pm
1 stop3h 55m
$308
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Mon 6/1
8:05 am-6:20 pm
2 stops10h 15m
Charleston
Mon 6/8
4:10 pm-10:30 pm
1 stop6h 20m
$324
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Thu 5/28
6:35 am-7:20 pm
2 stops12h 45m
Charleston
Thu 6/4
4:10 pm-10:30 pm
1 stop6h 20m
$329
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Fri 6/19
11:55 am-3:58 pm
1 stop4h 03m
Charleston
Sun 6/21
7:59 pm-11:54 pm
1 stop3h 55m
$337
KnoxvilleCharleston
TYS - CHS
TYSCHS
Knoxville McGhee Tyson
Wed 7/15
7:10 am-1:10 pm
1 stop6h 00m
Charleston
Wed 7/22
2:10 pm-8:20 pm
1 stop6h 10m
$337
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Charleston
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Charleston in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Knoxville with our price prediction graph.
TYS-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Charleston
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated May 4, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Knoxville to Charleston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Comfort
7.9
Overall
7.9
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Crew
8.5
Comfort
7.9
Overall
7.9
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Crew
8.5
Comfort
7.9
Overall
7.9
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 4, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Charleston by cabin class
Find flights from Knoxville to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Charleston flights
Browse other Knoxville and Charleston flight options. Last updated on May 4, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on May 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Charleston
Discover the top 2 airlines that operate flights from Knoxville to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$279 | Average$484 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$316 | Average$402 | FlexibilityNo cancel fee | On-timeN/A |