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$114+ Cheap flights from Des Moines (DSM) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
May 18 — May 251
Sun 5/18
Sun 5/25
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in August or June, booked 90 days in advance, depart on a Wednesday or Monday and return on a Wednesday

Cheap flight deals from Des Moines to Irvine

Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated May 13, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$188
(Mytrip)

One-way from

$114
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$405
Provider with most accurate pricing for Des Moines-Los Angeles flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Los Angeles flights.
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From Des Moines to Irvine
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One-way flight from Des Moines to Irvine
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($45 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Des Moines to Irvine

Cheapest flights from Des Moines to Irvine
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2025.

This Mytrip deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:30 amDSM - LAX
1 stop8h 36mMultiple Airlines
Wed 5/286:52 pmLAX - DSM
1 stop24h 39mMultiple Airlines
Deal found 5/12$188
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/298:41 pmDSM - LAX
1 stop5h 44mFrontier
Sun 8/316:15 amLAX - DSM
1 stop11h 41mFrontier
Deal found 5/12$240
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/42:15 pmDSM - LAX
1 stop9h 24mDelta
Wed 6/116:17 amLAX - DSM
1 stop5h 46mDelta
Deal found 5/10$257
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/195:30 amDSM - LAX
1 stop5h 44mAmerican Airlines
Thu 6/1911:45 amLAX - DSM
1 stop6h 28mAmerican Airlines
Deal found 5/10$288
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1312:15 pmDSM - LAX
2 stops7h 55mSouthwest
Wed 8/275:50 amLAX - DSM
1 stop8h 00mSouthwest
Deal found 5/11$311
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/38:00 amDSM - LAX
1 stop9h 20mUnited Airlines
Sat 6/214:11 pmLAX - DSM
1 stop5h 43mUnited Airlines
Deal found 5/11$312

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2025.
Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.

Fly from

Des Moines

Fly to

Irvine

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 5/28

7:30 am-2:06 pm

1 stop8h 36m

Los Angeles

Wed 5/28

6:52 pm-9:31 pm

1 stop24h 39m

$188

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 8/29

8:41 pm-12:25 am

1 stop5h 44m

Los Angeles

Sun 8/31

6:15 am-7:56 pm

1 stop11h 41m

$240

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 6/4

2:15 pm-9:39 pm

1 stop9h 24m

Los Angeles

Wed 6/11

6:17 am-2:03 pm

1 stop5h 46m

$257

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Thu 6/19

5:30 am-9:14 am

1 stop5h 44m

Los Angeles

Thu 6/19

11:45 am-8:13 pm

1 stop6h 28m

$288

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 8/13

12:15 pm-6:10 pm

2 stops7h 55m

Los Angeles

Wed 8/27

5:50 am-3:50 pm

1 stop8h 00m

$311

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 6/3

8:00 am-3:20 pm

1 stop9h 20m

Los Angeles

Sat 6/21

4:11 pm-11:54 pm

1 stop5h 43m

$312

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 6/25

1:58 pm-7:34 am

2 stops19h 36m

Los Angeles

Wed 7/2

8:52 am-10:30 pm

2 stops11h 38m

$597

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 6/18

7:30 am-6:59 am

1 stop25h 29m

$115

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Thu 8/28

8:41 pm-12:25 am

1 stop5h 44m

$119

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 6/18

7:00 am-1:04 pm

1 stop8h 04m

$129

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/12

Showing 1-10 of 14 results
1
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Best time to book a flight from Des Moines to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Irvine

How far ahead should I book a flight from Des Moines to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Irvine. Price data was last updated on May 9, 2025.

The price you pay for your flight from Des Moines to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Irvine?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $246). Flying from Des Moines to Irvine in March is currently the most expensive (average of $326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IR9?

Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 13, 2025.

When flying from Des Moines to Irvine, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Des Moines to Irvine?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Irvine. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Irvine flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Irvine by month

Plan your trip to Irvine by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Irvine ranges from 0.0 - 3.4 inches per month. February is typically the wettest month, when rainfall can reach 3.4 in. July is typically the driest time to visit Irvine when rainfall is around 0.0 in.

Temperature in Irvine by month

Plan your trip to Irvine by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Irvine, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated May 13, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from Des Moines to Irvine by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,290 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,949 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,726 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Comfort

7.9

Crew

8.5

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Irvine?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Irvine from Des Moines. Booking flights from Des Moines (DSM) to Irvine should be relatively easy as there are 0 daily outbound flights to Irvine from 6 different airlines.

  • How popular is this Des Moines to Irvine flight route?

    Flights from Des Moines to Irvine have been viewed 18 times in the past calendar month.

  • What are the cheapest airlines to fly from Des Moines to Irvine one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $114. Delta flights start at $129 while deals on Frontier start at $139 one-way.

  • What are the cheapest flights from Des Moines to Irvine?

    While on average a flight from Des Moines to Irvine is generally $783, our data shows the cheapest flight currently is $313. When looking at the most popular route, (Des Moines - Los Angeles), you can expect to pay $188 for that flight.

  • Can I find deals for flights from Des Moines to Irvine that include hotel bookings?

    Yes. In addition to deals on Des Moines to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Irvine.

  • Can I find deals for business class flights from Des Moines to Irvine?

    Yes. Cheapflights offers flight deals from Des Moines to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Irvine?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $246). Flying from Des Moines to Irvine in March is currently the most expensive (average of $326). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Des Moines to Irvine

Discover the top 6 airlines that operate flights from Des Moines to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$209FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$109Average$202FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$276Average$462FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$276Average$413FlexibilityNo cancel feeOn-time71%
DeltaCheapest$290Average$412FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$332Average$440FlexibilityNo cancel feeOn-time63%

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