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St. Louis

$61+ Cheap flights from San Diego to St. Louis (SAN - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Find cheap flights from San Diego to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from San Diego to Lambert-St Louis are usually found in September or February, booked 70 days in advance, depart on a Thursday or Friday and return on a Tuesday

Cheap flight deals from San Diego to St. Louis

Cheapest flights from San Diego to St. Louis
Explore the most affordable flight options available from San Diego to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:11 am
SAN
-
STL
1 stop6h 42m
Frontier
Sat 2/282:51 pm
STL
-
SAN
1 stop11h 17m
Frontier
Deal found 1/20$126
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:18 pm
SAN
-
STL
1 stop10h 31m
Frontier
Sun 3/89:22 pm
STL
-
SAN
1 stop20h 51m
Frontier
Deal found 1/20$151
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:30 am
SAN
-
STL
2 stops11h 32m
Frontier
Sat 2/282:51 pm
STL
-
SAN
1 stop11h 17m
Frontier
Deal found 1/21$156
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/178:00 am
SAN
-
STL
2 stops29h 53m
Frontier
Sat 2/212:51 pm
STL
-
SAN
1 stop11h 17m
Frontier
Deal found 1/21$165
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/299:45 pm
SAN
-
STL
1 stop12h 23m
Frontier
Sun 2/11:03 pm
STL
-
SAN
1 stop30h 00m
Frontier
Deal found 1/21$169
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:00 am
SAN
-
STL
1 stop5h 46m
Frontier
Sat 2/73:46 pm
STL
-
SAN
1 stop9h 45m
Frontier
Deal found 1/21$180
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:25 am
SAN
-
STL
1 stop29h 31m
Frontier
Wed 2/184:51 pm
STL
-
SAN
1 stop6h 50m
Frontier
Deal found 1/20$185
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:18 pm
SAN
-
STL
1 stop10h 31m
Frontier
Tue 3/108:06 pm
STL
-
SAN
1 stop19h 07m
Frontier
Deal found 1/20$189
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/59:45 pm
SAN
-
STL
1 stop12h 23m
Frontier
Fri 2/67:39 pm
STL
-
SAN
1 stop29h 52m
Frontier
Deal found 1/20$191
This WAYA deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:20 am
SAN
-
STL
1 stop8h 42m
Multiple Airlines
Sat 2/282:51 pm
STL
-
SAN
1 stop7h 36m
Multiple Airlines
Deal found 1/21$192

Find flight deals from San Diego to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$126
(Kiwi.com)

One-way from

$61
(Trip.com)

Popular in

December

Cheapest in

September

Average price

$389

Good round-trip deal

$408 or less

Good one-way deal

$218 or less
Provider with most accurate pricing for San Diego-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Lambert-St Louis flights.
Search Deals
From San Diego to Lambert-St Louis
Search Deals
One-way flight from San Diego to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from San Diego to Lambert-St Louis.
Search Deals
Price to beat on a one-way flight from San Diego to Lambert-St Louis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from San Diego to St. Louis that are best for you.

Fly from

San Diego

Fly to

St. Louis

Route

Depart

Return

Price

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Mon 2/23

6:30 am-8:02 pm

2 stops11h 32m

Lambert-St Louis

Sat 2/28

2:51 pm-12:08 am

1 stop11h 17m

$156

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Tue 2/17

8:00 am-3:53 pm

2 stops29h 53m

Lambert-St Louis

Sat 2/21

2:51 pm-12:08 am

1 stop11h 17m

$165

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 2/21

6:25 am-1:56 pm

1 stop5h 31m

Lambert-St Louis

Tue 2/24

7:00 am-1:20 pm

1 stop8h 20m

$219

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 5/10

6:25 pm-1:15 am

1 stop4h 50m

Lambert-St Louis

Fri 5/15

6:00 pm-11:05 pm

1 stop7h 05m

$285

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 3/6

12:05 pm-11:59 pm

1 stop9h 54m

Lambert-St Louis

Sun 3/8

7:00 am-3:46 pm

1 stop10h 46m

$289

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Mon 5/11

6:20 am-2:20 pm

1 stop6h 00m

Lambert-St Louis

Fri 5/15

6:00 pm-11:05 pm

1 stop7h 05m

$289

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sat 2/21

6:15 am-2:54 pm

1 stop6h 39m

Lambert-St Louis

Tue 2/24

2:22 pm-10:20 pm

2 stops9h 58m

$293

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Wed 2/25

10:59 am-11:23 pm

2 stops10h 24m

Lambert-St Louis

Sat 2/28

7:00 am-4:24 pm

2 stops11h 24m

$296

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Wed 2/4

7:00 am-9:06 pm

2 stops36h 06m

Lambert-St Louis

Fri 2/6

7:39 pm-11:31 pm

1 stop29h 52m

$299

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Mon 2/23

10:59 am-12:25 am

2 stops11h 26m

Lambert-St Louis

Sat 2/28

7:00 am-4:24 pm

2 stops11h 24m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 21 results
1
2
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Compare providers for flights from San Diego to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to St. Louis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-St. Louis flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to St. Louis

How far ahead should I book a flight from San Diego to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to St. Louis. Price data was last updated on January 16, 2026.

The best time to book flights from San Diego to St. Louis is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Diego to St. Louis?

Currently, September is the cheapest month in which you can book a flight from San Diego to St. Louis (average of $71). Flying from San Diego to St. Louis in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to STL?

Find hourly flight availability from San Diego to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 22, 2026.

When flying from San Diego to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

The best insider tips for San Diego to St. Louis flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Diego to St. Louis trip
Our travel experts
Blane Bachelor

Blane Bachelor

Expert on SAN

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Read more
Taryn White

Taryn White

Expert on STL

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated January 22, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Diego to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,087 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,190 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,174 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Frontier
5.7
Fair
3,057 reviews
Southwest
8.0
Very good
4,267 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Diego to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this San Diego to St. Louis flight route?

    Flights from San Diego to Lambert-St Louis have been viewed 3 times in the past calendar month.

  • How long is the flight from San Diego to St. Louis?

    Airlines like Frontier, Southwest, and Alaska Airlines fly from San Diego to St. Louis in about 4h 50m. The time it takes to get you to your destination can typically vary by up to 6h 42m. San Diego and St. Louis are separated by a distance of 1553 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Diego to St. Louis round-trip?

    Cheapflights users have booked flights from San Diego to St. Louis round-trip from $140. Other airlines that can offer you cheap pricing are Delta, from $148, and American Airlines, from $249. Frontier is priced at 63% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from San Diego to St. Louis one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $82. Users have also found prices from $116 and $128 on United Airlines and American Airlines, respectively.

  • What are the cheapest flights from San Diego to St. Louis?

    Looking for the cheapest flight from San Diego to St. Louis? While on average our users pay $349, our data indicates the cheapest price to be $168. The most popular route (San Diego - Lambert-St Louis), is priced around $191.

  • Can I find deals for flights from San Diego to St. Louis that include hotel bookings?

    Yes. In addition to deals on San Diego to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to St. Louis.

  • Can I find deals for business class flights from San Diego to St. Louis?

    Yes. Cheapflights offers flight deals from San Diego to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to St. Louis?

    Currently, September is the cheapest month in which you can book a flight from San Diego to St. Louis (average of $71). Flying from San Diego to St. Louis in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from San Diego to St. Louis

Discover the top 5 airlines that operate flights from San Diego to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$140Average$238FlexibilityNo cancel feeOn-time62%
DeltaCheapest$148Average$277FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$336FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$256Average$366FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$306Average$481FlexibilityNo cancel feeOn-time63%

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