$84+ Cheap flights from San Diego to St. Louis (SAN - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Jul 18 — Jul 251
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Lambert-St Louis are usually found in September or May, booked 75 days in advance, depart on a Thursday or Friday and return on a Wednesday
Cheap flight deals from San Diego to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to St. LouisExplore the most affordable flight options available from San Diego to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
Explore the most affordable flight options available from San Diego to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/214:12 pm
SAN
- STL
2 stops23h 53m
Frontier
Thu 7/237:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/15![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/214:12 pm
SAN
- STL
2 stops23h 53m
Frontier
Thu 7/307:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/15![Frontier logo]()
$250
This Trip.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:00 am
SAN
- STL
1 stop7h 23m
Frontier
Fri 8/78:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/13![Frontier logo]()
$253
This Frontier deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:25 am
SAN
- STL
1 stop10h 50m
Frontier
Tue 10/138:10 pm
STL
- SAN
1 stop5h 49m
Frontier
Deal found 6/16![Frontier logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:38 pm
SAN
- STL
2 stops23h 37m
Frontier
Tue 7/218:08 pm
STL
- SAN
1 stop29h 43m
Frontier
Deal found 6/16![Frontier logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Mon 8/177:10 pm
STL
- SAN
2 stops22h 22m
Frontier
Deal found 6/15![Frontier logo]()
$257
This Frontier deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:25 am
SAN
- STL
1 stop9h 53m
Frontier
Tue 6/308:08 pm
STL
- SAN
1 stop5h 45m
Frontier
Deal found 6/14![Frontier logo]()
$258
This Orbitz deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Thu 7/98:08 pm
STL
- SAN
1 stop14h 57m
Frontier
Deal found 6/17![Frontier logo]()
$259
This Booking.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sun 7/197:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/17![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sun 7/197:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/17![Frontier logo]()
$263
This CheapOair deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Wed 7/298:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/16![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Thu 7/307:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/14![Frontier logo]()
$267
Best flights from San Diego to St. LouisDiscover carefully curated flight deals from San Diego to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
Discover carefully curated flight deals from San Diego to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:46 am
SAN
- STL
1 stop7h 09m
Delta
Sun 8/236:00 am
STL
- SAN
1 stop7h 07m
Delta
Deal found 6/16![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:30 am
SAN
- STL
Nonstop3h 40m
Southwest
Sat 8/84:20 pm
STL
- SAN
1 stop6h 40m
Southwest
Deal found 6/17![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:07 pm
SAN
- STL
1 stop5h 50m
United Airlines
Sat 7/45:10 am
STL
- SAN
2 stops8h 41m
United Airlines
Deal found 6/16![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:55 pm
SAN
- STL
1 stop5h 00m
Southwest
Sat 7/188:50 pm
STL
- SAN
Nonstop3h 50m
Southwest
Deal found 6/17![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:00 am
SAN
- STL
1 stop7h 46m
United Airlines
Mon 8/311:36 pm
STL
- SAN
2 stops8h 19m
United Airlines
Deal found 6/13![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:05 am
SAN
- STL
Nonstop3h 40m
Southwest
Fri 7/245:45 am
STL
- SAN
1 stop5h 25m
Southwest
Deal found 6/15![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:39 pm
SAN
- STL
2 stops8h 18m
United Airlines
Fri 7/105:59 pm
STL
- SAN
1 stop6h 35m
United Airlines
Deal found 6/17![United Airlines logo]()
$443
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:40 pm
SAN
- STL
1 stop7h 10m
Southwest
Fri 7/108:10 am
STL
- SAN
Nonstop3h 40m
Southwest
Deal found 6/17![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:40 am
SAN
- STL
2 stops7h 05m
Southwest
Thu 7/95:45 am
STL
- SAN
1 stop5h 25m
Southwest
Deal found 6/14![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:35 am
SAN
- STL
1 stop6h 45m
Southwest
Fri 8/218:25 am
STL
- SAN
Nonstop3h 45m
Southwest
Deal found 6/17![Southwest logo]()
$449
Last-minute flights from San Diego to St. LouisDiscover last-minute flight deals from San Diego to St. Louis. Data last updated June 18, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to St. Louis. Data last updated June 18, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:25 am
SAN
- STL
1 stop9h 53m
Frontier
Fri 7/37:38 pm
STL
- SAN
1 stop6h 15m
Frontier
Deal found 6/14![Frontier logo]()
$258
This Trip.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/49:37 am
SAN
- STL
1 stop7h 16m
Frontier
Fri 7/107:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/16![Frontier logo]()
$272
This Orbitz deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Thu 7/98:08 pm
STL
- SAN
1 stop14h 57m
Frontier
Deal found 6/17![Frontier logo]()
$259
This CheapOair deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:35 am
SAN
- STL
1 stop6h 21m
Frontier
Sun 7/127:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/17![Frontier logo]()
$268
This Booking.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sun 7/197:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/17![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:38 pm
SAN
- STL
2 stops23h 37m
Frontier
Tue 7/218:08 pm
STL
- SAN
1 stop29h 43m
Frontier
Deal found 6/16![Frontier logo]()
$255
This CheapOair deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:25 am
SAN
- STL
1 stop10h 58m
Frontier
Sun 7/197:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/17![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Thu 7/307:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/14![Frontier logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/214:12 pm
SAN
- STL
2 stops23h 53m
Frontier
Thu 7/237:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/15![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/214:12 pm
SAN
- STL
2 stops23h 53m
Frontier
Thu 7/307:10 pm
STL
- SAN
1 stop26h 56m
Frontier
Deal found 6/15![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Wed 7/298:08 pm
STL
- SAN
1 stop5h 43m
Frontier
Deal found 6/16![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Mon 8/37:10 pm
STL
- SAN
1 stop20h 58m
Frontier
Deal found 6/13![Frontier logo]()
$275
One-way flights from San Diego to St. LouisSearch for one-way flight options from San Diego to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
Search for one-way flight options from San Diego to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/17![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:03 pm
SAN
- STL
1 stop25h 02m
Frontier
Deal found 6/17![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 6/16![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:03 pm
SAN
- STL
1 stop25h 02m
Frontier
Deal found 6/18![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:51 pm
SAN
- STL
1 stop19h 14m
Frontier
Deal found 6/17![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:03 pm
SAN
- STL
1 stop25h 12m
Frontier
Deal found 6/13![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:51 pm
SAN
- STL
1 stop19h 24m
Frontier
Deal found 6/15![Frontier logo]()
$96
Find flight deals from San Diego to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Kiwi.com) |
One-way from | $84 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $375 |
Good round-trip deal | $502 or less |
Good one-way deal | $244 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from San Diego to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Thu 8/20
9:46 am-6:55 pm
1 stop7h 09m
Lambert-St Louis
Sun 8/23
6:00 am-11:07 am
1 stop7h 07m
$297
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Sat 8/1
6:30 am-12:10 pm
Nonstop3h 40m
Lambert-St Louis
Sat 8/8
4:20 pm-9:00 pm
1 stop6h 40m
$373
Quickest round-trip
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Thu 7/16
6:55 pm-1:55 am
1 stop5h 00m
Lambert-St Louis
Sat 7/18
8:50 pm-10:40 pm
Nonstop3h 50m
$373
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 7/21
7:05 am-12:45 pm
Nonstop3h 40m
Lambert-St Louis
Fri 7/24
5:45 am-9:10 am
1 stop5h 25m
$382
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Wed 7/1
4:07 pm-11:57 pm
1 stop5h 50m
Lambert-St Louis
Sat 7/4
5:10 am-11:51 am
2 stops8h 41m
$383
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Wed 8/26
11:00 am-8:46 pm
1 stop7h 46m
Lambert-St Louis
Mon 8/31
1:36 pm-7:55 pm
2 stops8h 19m
$402
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 7/3
10:40 pm-7:50 am
1 stop7h 10m
Lambert-St Louis
Fri 7/10
8:10 am-9:50 am
Nonstop3h 40m
$417
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 7/3
1:39 pm-11:57 pm
2 stops8h 18m
Lambert-St Louis
Fri 7/10
5:59 pm-10:34 pm
1 stop6h 35m
$443
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Wed 7/8
8:40 am-5:45 pm
2 stops7h 05m
Lambert-St Louis
Thu 7/9
5:45 am-9:10 am
1 stop5h 25m
$443
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Sun 8/16
6:35 am-3:20 pm
1 stop6h 45m
Lambert-St Louis
Fri 8/21
8:25 am-10:10 am
Nonstop3h 45m
$449
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Diego to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to St. Louis in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Diego-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from San Diego with our price prediction graph.
SAN-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to St. Louis
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How far ahead should I book a flight from San Diego to St. Louis?
The best time to book flights from San Diego to St. Louis is 74 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Diego to St. Louis?
Currently, September is the cheapest month in which you can book a flight from San Diego to St. Louis (average of $290). Flying from San Diego to St. Louis in December is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to STL?
Find hourly flight availability from San Diego to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2026.
When flying from San Diego to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from San Diego to St. Louis?
Share of 1-stop round-trip flights from San Diego to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Denver (DEN) – chosen by Cheapflights users on 50% of 1-stop itineraries from San Diego to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from San Diego to St. Louis?
Average round-trip fare for 1-stop flights from San Diego to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $141.
What’s the fastest layover option from San Diego to St. Louis?
Shortest average travel time for 1-stop one-way flights from San Diego to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Las Vegas (LAS) have the shortest average one-way travel time for 1-stop routes: 6h 07m.
Which airport typically offers the quickest layover for flights from San Diego to St. Louis?
Average layover duration for 1-stop one-way flights from San Diego to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Las Vegas (LAS) offer the fastest connection on this route, with an average layover time of 3h 29m.
The best insider tips for San Diego to St. Louis flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Diego to St. Louis trip
Our travel experts
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 18, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
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San Diego and St. Louis flights
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Top 7 airlines flying from San Diego to St. Louis
Discover the top 7 airlines that operate flights from San Diego to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$140 | Average$240 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$209 | Average$386 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$232 | Average$375 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$236 | Average$380 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$372 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$369 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$281 | Average$457 | FlexibilityNo cancel fee | On-time63% |