Plan to arrive at SAN at least two hours before your flight to avoid stress from traffic congestion near the airport.
$52+ Cheap flights from San Diego to St. Louis (SAN - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — STL
Feb 7 — Feb 141
1 adult, Economy
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Find cheap flights from San Diego to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Lambert-St Louis are usually found in September or February, booked 70 days in advance, depart on a Thursday or Friday and return on a Wednesday
Cheap flight deals from San Diego to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $128 (Kiwi.com) |
One-way from | $52 (Trip.com) |
Popular in | December |
Cheapest in | September |
Average price | $373 |
Good round-trip deal | $463 or less |
Good one-way deal | $218 or less |
Find flight deals from San Diego to St. Louis
Cheapest flights from San Diego to St. LouisExplore the most affordable flight options available from San Diego to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.
Explore the most affordable flight options available from San Diego to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:35 amSAN - STL
1 stop27h 21mFrontier
Mon 3/21:54 pmSTL - SAN
1 stop12h 14mFrontier
Deal found 1/7![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/308:16 pmSAN - STL
1 stop16h 30mFrontier
Mon 2/21:40 pmSTL - SAN
1 stop12h 28mFrontier
Deal found 1/5![Frontier logo]()
$132
This CheapOair deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/287:00 amSAN - STL
1 stop5h 46mFrontier
Thu 1/2910:01 pmSTL - SAN
1 stop13h 25mFrontier
Deal found 1/7![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:09 amSAN - STL
1 stop26h 00mFrontier
Wed 3/45:18 pmSTL - SAN
2 stops26h 33mFrontier
Deal found 1/5![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3110:34 amSAN - STL
1 stop22h 44mFrontier
Mon 2/21:40 pmSTL - SAN
1 stop12h 28mFrontier
Deal found 1/5![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:00 amSAN - STL
2 stops38h 33mFrontier
Fri 2/67:39 pmSTL - SAN
1 stop29h 52mFrontier
Deal found 1/5![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:11 amSAN - STL
1 stop6h 42mFrontier
Mon 3/21:54 pmSTL - SAN
1 stop12h 14mFrontier
Deal found 1/7![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/126:25 amSAN - STL
1 stop28h 44mFrontier
Mon 2/1610:11 pmSTL - SAN
2 stops49h 30mFrontier
Deal found 1/7![Frontier logo]()
$173
This CheapOair deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/287:00 amSAN - STL
1 stop5h 46mFrontier
Wed 2/43:46 pmSTL - SAN
1 stop21h 08mFrontier
Deal found 1/7![Frontier logo]()
$178
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from San Diego to St. Louis that are best for you.
Fly from
San Diego
Fly to
St. Louis
Route
Depart
Return
Price
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 2/3
7:00 am-11:33 pm
2 stops38h 33m
Lambert-St Louis
Fri 2/6
7:39 pm-11:31 pm
1 stop29h 52m
$157
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Sun 3/29
10:02 pm-11:19 am
1 stop11h 17m
Lambert-St Louis
Thu 4/2
7:43 pm-7:15 pm
1 stop25h 32m
$181
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Sat 1/31
10:34 am-8:24 am
2 stops19h 50m
Lambert-St Louis
Mon 2/2
1:40 pm-12:08 am
1 stop12h 28m
$187
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Fri 3/13
9:28 pm-9:49 am
1 stop10h 21m
Lambert-St Louis
Mon 3/16
8:12 pm-9:14 pm
1 stop27h 02m
$191
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 2/10
7:11 am-1:58 pm
1 stop28h 47m
Lambert-St Louis
Thu 2/12
10:11 pm-7:23 pm
1 stop23h 12m
$247
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Mon 2/23
10:59 am-12:25 am
2 stops11h 26m
Lambert-St Louis
Thu 2/26
6:10 am-2:29 pm
2 stops10h 19m
$254
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Thu 2/12
10:59 am-11:23 pm
2 stops10h 24m
Lambert-St Louis
Tue 2/17
2:22 pm-10:20 pm
2 stops9h 58m
$254
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Wed 2/11
7:00 am-11:25 pm
2 stops14h 25m
Lambert-St Louis
Tue 2/17
7:00 am-5:50 pm
2 stops12h 50m
$254
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 3/31
7:30 am-12:21 am
2 stops14h 51m
Lambert-St Louis
Tue 4/7
2:15 pm-6:35 pm
1 stop6h 20m
$262
San DiegoSt. Louis
SAN - STL
SANSTL
San Diego
Tue 2/3
4:01 pm-1:54 pm
1 stop19h 53m
Lambert-St Louis
Tue 2/10
2:50 pm-7:17 am
2 stops18h 27m
$269
Showing 1-10 of 20 results
Compare providers for flights from San Diego to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to St. Louis in January.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*2 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to St. Louis
Prices
More
How far ahead should I book a flight from San Diego to St. Louis?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to St. Louis. Price data was last updated on January 2, 2026.
The best time to book flights from San Diego to St. Louis is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Diego to St. Louis?
Currently, September is the cheapest month in which you can book a flight from San Diego to St. Louis (average of $71). Flying from San Diego to St. Louis in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to STL?
Find hourly flight availability from San Diego to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 8, 2026.
When flying from San Diego to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from San Diego to St. Louis?
Share of 1-stop round-trip flights from San Diego to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Denver (DEN) – chosen by Cheapflights users on 50% of 1-stop itineraries from San Diego to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from San Diego to St. Louis?
Average round-trip fare for 1-stop flights from San Diego to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $141.
What’s the fastest layover option from San Diego to St. Louis?
Shortest average travel time for 1-stop one-way flights from San Diego to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Las Vegas (LAS) have the shortest average one-way travel time for 1-stop routes: 6h 07m.
Which airport typically offers the quickest layover for flights from San Diego to St. Louis?
Average layover duration for 1-stop one-way flights from San Diego to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Las Vegas (LAS) offer the fastest connection on this route, with an average layover time of 3h 29m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated January 8, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Diego to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Diego to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from San Diego to St. Louis
Discover the top 5 airlines that operate flights from San Diego to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$137 | Average$237 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$184 | Average$278 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$249 | Average$334 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$366 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$306 | Average$479 | FlexibilityNo cancel fee | On-time63% |