$86+ Cheap flights from Iowa to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to St. Louis
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Cheapest flights from Iowa to St. LouisExplore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:49 pm -
1 stop4h 25m
Tue 8/116:00 am -
1 stop3h 56m
Deal found 8/5![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop3h 23m
Thu 9/176:15 am -
1 stop4h 02m
Deal found 8/5![Delta logo]()
$232
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:15 pm -
Nonstop1h 20m
Sun 9/66:50 pm -
Nonstop1h 15m
Deal found 8/5![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop4h 50m
Thu 9/1711:40 am -
2 stops10h 35m
Deal found 8/5![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:57 am -
1 stop3h 48m
Sat 11/75:33 pm -
1 stop3h 29m
Deal found 8/4![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:10 pm -
2 stops7h 40m
Sat 9/2612:45 pm -
1 stop8h 05m
Deal found 8/5![Southwest logo]()
$250
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:11 pm -
1 stop6h 49m
Sun 9/68:30 am -
1 stop5h 45m
Deal found 8/5![United Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:25 pm -
1 stop7h 35m
Fri 9/116:15 pm -
1 stop4h 00m
Deal found 8/7![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:40 pm -
Nonstop1h 15m
Thu 9/38:30 am -
Nonstop1h 15m
Deal found 8/7![Southwest logo]()
$261
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:35 am -
2 stops9h 20m
Sat 10/179:25 am -
2 stops11h 20m
Deal found 8/5![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:11 pm -
1 stop6h 06m
Thu 9/38:00 am -
1 stop4h 20m
Deal found 8/7![United Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm -
1 stop5h 57m
Mon 9/78:00 am -
1 stop6h 16m
Deal found 8/4![United Airlines logo]()
$271
Best flights from Iowa to St. LouisDiscover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:15 pm -
Nonstop1h 20m
Sun 9/66:50 pm -
Nonstop1h 15m
Deal found 8/7![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop6h 13m
Sat 10/109:04 am -
1 stop5h 11m
Deal found 8/6![United Airlines logo]()
$245
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:58 am -
1 stop14h 15m
Mon 10/2611:31 am -
1 stop12h 28m
Deal found 8/8![American Airlines logo]()
$454
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:40 am -
1 stop3h 35m
Mon 9/286:15 pm -
1 stop4h 00m
Deal found 8/6![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm -
1 stop6h 40m
Mon 9/78:30 am -
1 stop3h 50m
Deal found 8/5![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 am -
2 stops9h 25m
Sat 10/104:40 pm -
1 stop4h 05m
Deal found 8/6![Southwest logo]()
$250
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:11 pm -
1 stop6h 06m
Thu 9/38:00 am -
1 stop4h 20m
Deal found 8/7![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:40 pm -
Nonstop1h 15m
Thu 9/38:30 am -
Nonstop1h 15m
Deal found 8/7![Southwest logo]()
$261
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:25 pm -
1 stop7h 35m
Fri 9/113:15 pm -
2 stops7h 00m
Deal found 8/7![Southwest logo]()
$263
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:23 am -
1 stop4h 20m
Sat 11/78:30 am -
1 stop5h 56m
Deal found 8/4![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm -
1 stop6h 20m
Thu 9/176:05 am -
1 stop5h 20m
Deal found 8/7![Southwest logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:13 pm -
1 stop6h 08m
Thu 10/88:00 am -
1 stop4h 14m
Deal found 8/6![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:01 am -
1 stop4h 51m
Sat 11/1411:29 am -
1 stop6h 47m
Deal found 8/8![American Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 am -
2 stops7h 35m
Sun 11/14:30 pm -
2 stops6h 30m
Deal found 8/5![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:00 am -
1 stop3h 24m
Wed 8/269:32 am -
1 stop5h 20m
Deal found 8/7![American Airlines logo]()
$550
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:10 am -
Nonstop1h 10m
Fri 10/99:50 pm -
Nonstop1h 15m
Deal found 8/7![Southwest logo]()
$344
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:55 pm -
1 stop5h 14m
Wed 10/2812:51 pm -
2 stops11h 08m
Deal found 8/8![American Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:14 pm -
1 stop3h 43m
Sun 8/235:00 am -
1 stop6h 23m
Deal found 8/6![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:20 pm -
1 stop26h 07m
Mon 8/318:07 pm -
1 stop15h 42m
Deal found 8/9![American Airlines logo]()
$651
Last-minute flights from Iowa to St. LouisDiscover last-minute flight deals from Iowa to St. Louis. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to St. Louis. Data last updated August 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:49 pm -
1 stop4h 25m
Tue 8/116:00 am -
1 stop3h 56m
Deal found 8/5![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:40 pm -
Nonstop1h 15m
Thu 9/38:30 am -
Nonstop1h 15m
Deal found 8/7![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:11 pm -
1 stop6h 06m
Thu 9/38:00 am -
1 stop4h 20m
Deal found 8/7![United Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:49 pm -
1 stop4h 25m
Thu 9/105:18 pm -
1 stop6h 46m
Deal found 8/6![American Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:25 pm -
1 stop7h 35m
Fri 9/116:15 pm -
1 stop4h 00m
Deal found 8/7![Southwest logo]()
$258
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm -
1 stop5h 57m
Mon 9/78:00 am -
1 stop6h 16m
Deal found 8/4![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:15 pm -
Nonstop1h 20m
Sun 9/66:50 pm -
Nonstop1h 15m
Deal found 8/5![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:11 pm -
1 stop6h 49m
Sun 9/68:30 am -
1 stop5h 45m
Deal found 8/5![United Airlines logo]()
$257
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am -
1 stop3h 23m
Thu 9/176:15 am -
1 stop4h 02m
Deal found 8/5![Delta logo]()
$232
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop4h 50m
Thu 9/1711:40 am -
2 stops10h 35m
Deal found 8/5![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:10 pm -
2 stops7h 40m
Sat 9/2612:45 pm -
1 stop8h 05m
Deal found 8/5![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:40 am -
2 stops9h 40m
Mon 9/283:15 pm -
2 stops7h 00m
Deal found 8/6![Southwest logo]()
$281
One-way flights from Iowa to St. LouisSearch for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Frontier deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:18 pm -
1 stop4h 55m
Deal found 8/5![Frontier logo]()
$86
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am -
1 stop4h 12m
Deal found 8/7![United Airlines logo]()
$110
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:15 pm -
Nonstop1h 20m
Deal found 8/6![Southwest logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:41 pm -
1 stop22h 34m
Deal found 8/7![Frontier logo]()
$127
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:10 am -
2 stops8h 15m
Deal found 8/5![Southwest logo]()
$128
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:02 am -
1 stop4h 10m
Deal found 8/7![United Airlines logo]()
$129
This Frontier deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:18 pm -
1 stop4h 55m
Deal found 8/7![Frontier logo]()
$130
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:10 am -
Nonstop1h 10m
Deal found 8/6![Southwest logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/201:58 pm -
2 stops23h 12m
Deal found 8/9![Multiple Airlines logo]()
$131
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/45:35 pm -
1 stop5h 43m
Deal found 8/7![Delta logo]()
$136
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:40 pm -
Nonstop1h 15m
Deal found 8/8![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:30 am -
2 stops23h 10m
Deal found 8/7![Multiple Airlines logo]()
$148
Find flight deals from Iowa to St. Louis
Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $219 (American Airlines) |
One-way from | $86 (Frontier) |
Popular in | February |
Cheapest in | May |
Average price | $374 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Sat 9/5
2:15 pm-3:35 pm
Nonstop1h 20m
Lambert-St Louis
Sun 9/6
6:50 pm-8:05 pm
Nonstop1h 15m
$237
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 10/7
6:00 am-12:13 pm
1 stop6h 13m
Lambert-St Louis
Sat 10/10
9:04 am-2:15 pm
1 stop5h 11m
$245
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 9/21
5:40 am-9:15 am
1 stop3h 35m
Lambert-St Louis
Mon 9/28
6:15 pm-10:15 pm
1 stop4h 00m
$245
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 10/7
5:35 am-3:00 pm
2 stops9h 25m
Lambert-St Louis
Sat 10/10
4:40 pm-8:45 pm
1 stop4h 05m
$250
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Tue 9/1
4:40 pm-5:55 pm
Nonstop1h 15m
Lambert-St Louis
Thu 9/3
8:30 am-9:45 am
Nonstop1h 15m
$261
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 9/4
2:25 pm-10:00 pm
1 stop7h 35m
Lambert-St Louis
Fri 9/11
3:15 pm-10:15 pm
2 stops7h 00m
$263
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 9/4
3:20 pm-10:00 pm
1 stop6h 40m
Lambert-St Louis
Mon 9/7
8:30 am-12:20 pm
1 stop3h 50m
$271
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Tue 9/1
3:11 pm-9:17 pm
1 stop6h 06m
Lambert-St Louis
Thu 9/3
8:00 am-12:20 pm
1 stop4h 20m
$271
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Thu 9/10
3:50 pm-10:10 pm
1 stop6h 20m
Lambert-St Louis
Thu 9/17
6:05 am-11:25 am
1 stop5h 20m
$271
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 10/30
5:10 am-12:45 pm
2 stops7h 35m
Lambert-St Louis
Sun 11/1
4:30 pm-11:00 pm
2 stops6h 30m
$299
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Iowa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
DSM-STL
OMA-STL
LSE-STL
ALO-STL
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USIA-STL
DSM-STL
OMA-STL
LSE-STL
ALO-STL
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Related info for your journey
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Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Iowa and St. Louis flights
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Top 2 airlines flying from Iowa to St. Louis
Discover the top 2 airlines that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$374 | FlexibilityNo cancel fee | On-time71% |