$82+ Cheap flights from Iowa to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Jun 9 — Jun 161
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to St. Louis
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Cheapest flights from Iowa to St. LouisExplore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Tue 6/168:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Deal found 5/6![Frontier logo]()
$239
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:05 pm
OMA
- STL
1 stop23h 18m
Frontier
Mon 7/208:08 pm
STL
- OMA
1 stop23h 12m
Frontier
Deal found 5/8![Frontier logo]()
$242
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$252
This Booking.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Sat 6/137:38 pm
STL
- OMA
1 stop23h 52m
Frontier
Deal found 5/10![Frontier logo]()
$256
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Mon 5/258:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 5/6![Frontier logo]()
$260
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 5/278:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:05 pm
OMA
- STL
1 stop23h 18m
Frontier
Tue 8/118:08 pm
STL
- OMA
1 stop23h 12m
Frontier
Deal found 5/8![Frontier logo]()
$262
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 6/178:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 5/8![Southwest logo]()
$265
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:10 am
OMA
- STL
Nonstop1h 15m
Southwest
Mon 8/248:45 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 5/7![Southwest logo]()
$269
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Thu 6/48:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$273
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:00 am
OMA
- STL
1 stop5h 34m
United Airlines
Mon 8/248:30 pm
STL
- OMA
1 stop4h 15m
United Airlines
Deal found 5/7![United Airlines logo]()
$279
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:16 pm
DSM
- STL
1 stop5h 07m
Frontier
Thu 6/48:08 pm
STL
- DSM
1 stop17h 23m
Frontier
Deal found 5/6![Frontier logo]()
$280
Best flights from Iowa to St. LouisDiscover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:55 pm
OMA
- STL
1 stop5h 00m
Southwest
Wed 6/178:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 5/8![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
DSM
- STL
1 stop6h 11m
United Airlines
Wed 6/35:29 pm
STL
- DSM
1 stop5h 22m
United Airlines
Deal found 5/7![United Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:52 pm
OMA
- STL
1 stop5h 31m
Delta
Wed 6/173:57 pm
STL
- OMA
1 stop3h 51m
Delta
Deal found 5/9![Delta logo]()
$345
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:34 pm
LSE
- STL
1 stop6h 20m
American Airlines
Mon 5/256:00 am
STL
- LSE
1 stop5h 22m
American Airlines
Deal found 5/6![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:20 am
DSM
- STL
2 stops9h 30m
Southwest
Wed 7/11:45 pm
STL
- DSM
1 stop7h 55m
Southwest
Deal found 5/10![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:05 am
OMA
- STL
2 stops9h 45m
Southwest
Mon 8/243:15 pm
STL
- OMA
2 stops6h 50m
Southwest
Deal found 5/7![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 pm
OMA
- STL
1 stop4h 50m
United Airlines
Wed 9/21:36 pm
STL
- OMA
1 stop7h 06m
United Airlines
Deal found 5/6![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
DSM
- STL
1 stop4h 15m
Southwest
Fri 7/176:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 5/10![Southwest logo]()
$305
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:30 am
DSM
- STL
2 stops7h 20m
Southwest
Wed 6/1010:15 am
STL
- DSM
2 stops12h 30m
Southwest
Deal found 5/6![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:20 am
DSM
- STL
2 stops9h 25m
Southwest
Wed 6/2410:15 am
STL
- DSM
2 stops12h 30m
Southwest
Deal found 5/7![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:34 pm
LSE
- STL
1 stop6h 20m
American Airlines
Wed 5/276:00 am
STL
- LSE
1 stop5h 22m
American Airlines
Deal found 5/7![American Airlines logo]()
$498
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am
DSM
- STL
2 stops7h 45m
Southwest
Sun 9/64:30 pm
STL
- DSM
1 stop4h 45m
Southwest
Deal found 5/9![Southwest logo]()
$310
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:40 am
LSE
- STL
2 stops7h 42m
American Airlines
Tue 5/267:50 pm
STL
- LSE
1 stop4h 16m
American Airlines
Deal found 5/7![American Airlines logo]()
$504
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:40 am
DSM
- STL
1 stop3h 35m
Southwest
Mon 8/106:15 pm
STL
- DSM
1 stop3h 55m
Southwest
Deal found 5/6![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:40 pm
DSM
- STL
1 stop6h 10m
Southwest
Fri 6/196:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 5/7![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:02 pm
ALO
- STL
1 stop4h 18m
American Airlines
Thu 5/289:08 am
STL
- ALO
1 stop5h 24m
American Airlines
Deal found 5/9![American Airlines logo]()
$546
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:55 pm
DSM
- STL
1 stop4h 50m
Southwest
Sat 6/274:45 pm
STL
- DSM
1 stop5h 10m
Southwest
Deal found 5/6![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:40 pm
DSM
- STL
1 stop6h 10m
Southwest
Mon 6/156:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 5/9![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:01 pm
LSE
- STL
1 stop12h 15m
American Airlines
Fri 7/107:56 pm
STL
- LSE
1 stop15h 35m
American Airlines
Deal found 5/10![American Airlines logo]()
$596
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:30 pm
DSM
- STL
1 stop6h 50m
Southwest
Sun 7/55:50 am
STL
- DSM
1 stop5h 35m
Southwest
Deal found 5/8![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:34 pm
LSE
- STL
1 stop6h 20m
American Airlines
Sat 5/307:00 am
STL
- LSE
1 stop4h 14m
American Airlines
Deal found 5/9![American Airlines logo]()
$614
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Sat 6/2710:15 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 5/6![Southwest logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:52 am
LSE
- STL
2 stops11h 52m
American Airlines
Fri 5/297:50 pm
STL
- LSE
1 stop15h 24m
American Airlines
Deal found 5/7![American Airlines logo]()
$626
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Fri 9/48:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 5/6![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:15 am
OMA
- STL
2 stops8h 30m
Southwest
Thu 6/116:30 pm
STL
- OMA
1 stop4h 25m
Southwest
Deal found 5/5![Southwest logo]()
$356
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 6/38:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 5/8![Southwest logo]()
$358
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:23 pm
ALO
- STL
1 stop5h 10m
American Airlines
Tue 5/198:55 am
STL
- ALO
1 stop4h 58m
American Airlines
Deal found 5/8![American Airlines logo]()
$810
Last-minute flights from Iowa to St. LouisDiscover last-minute flight deals from Iowa to St. Louis. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to St. Louis. Data last updated May 10, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Mon 5/258:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 5/6![Frontier logo]()
$260
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 5/278:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$252
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Thu 6/48:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$273
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:16 pm
DSM
- STL
1 stop5h 07m
Frontier
Thu 6/48:08 pm
STL
- DSM
1 stop17h 23m
Frontier
Deal found 5/6![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:16 pm
DSM
- STL
1 stop29h 07m
Multiple Airlines
Wed 6/105:06 pm
STL
- DSM
2 stops29h 52m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$292
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
DSM
- STL
1 stop6h 11m
United Airlines
Wed 6/35:29 pm
STL
- DSM
1 stop5h 22m
United Airlines
Deal found 5/7![United Airlines logo]()
$293
This Booking.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Sat 6/137:38 pm
STL
- OMA
1 stop23h 52m
Frontier
Deal found 5/10![Frontier logo]()
$256
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Tue 6/168:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Deal found 5/6![Frontier logo]()
$239
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 6/178:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 5/8![Southwest logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:25 pm
OMA
- STL
2 stops12h 27m
Frontier
Wed 6/178:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Deal found 5/8![Frontier logo]()
$290
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/171:10 pm
OMA
- STL
2 stops7h 15m
Southwest
Tue 6/308:35 am
STL
- OMA
2 stops6h 00m
Southwest
Deal found 5/8![Southwest logo]()
$295
One-way flights from Iowa to St. LouisSearch for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/5![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/5![Frontier logo]()
$84
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Deal found 5/7![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/5![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
2 stops21h 14m
Frontier
Deal found 5/6![Frontier logo]()
$131
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 5/5![Southwest logo]()
$133
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/9![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:15 pm
OMA
- STL
2 stops12h 42m
Frontier
Deal found 5/8![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2610:57 am
DSM
- STL
2 stops22h 00m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$137
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:00 am
DSM
- STL
1 stop6h 11m
United Airlines
Deal found 5/10![United Airlines logo]()
$159
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:01 am
DSM
- STL
1 stop3h 31m
Delta
Deal found 5/7![Delta logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:00 am
DSM
- STL
2 stops34h 30m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$184
Find flight deals from Iowa to St. Louis
Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $222 (Booking.com) |
One-way from | $82 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $237 |
Good round-trip deal | $105 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Tue 6/16
6:55 pm-11:55 pm
1 stop5h 00m
Lambert-St Louis
Wed 6/17
8:35 am-9:50 am
Nonstop1h 15m
$275
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 6/3
6:00 am-12:11 pm
1 stop6h 11m
Lambert-St Louis
Wed 6/3
5:29 pm-10:51 pm
1 stop5h 22m
$293
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 6/24
5:20 am-2:50 pm
2 stops9h 30m
Lambert-St Louis
Wed 7/1
1:45 pm-9:40 pm
1 stop7h 55m
$298
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Sat 8/22
7:05 am-4:50 pm
2 stops9h 45m
Lambert-St Louis
Mon 8/24
3:15 pm-10:05 pm
2 stops6h 50m
$299
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 7/7
5:20 am-9:35 am
1 stop4h 15m
Lambert-St Louis
Fri 7/17
6:30 pm-11:30 pm
1 stop5h 00m
$305
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 6/3
5:30 am-12:50 pm
2 stops7h 20m
Lambert-St Louis
Wed 6/10
10:15 am-10:45 pm
2 stops12h 30m
$309
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 6/17
5:20 am-2:45 pm
2 stops9h 25m
Lambert-St Louis
Wed 6/24
10:15 am-10:45 pm
2 stops12h 30m
$309
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 9/2
6:10 am-1:55 pm
2 stops7h 45m
Lambert-St Louis
Sun 9/6
4:30 pm-9:15 pm
1 stop4h 45m
$310
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/6
5:40 am-9:15 am
1 stop3h 35m
Lambert-St Louis
Mon 8/10
6:15 pm-10:10 pm
1 stop3h 55m
$317
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 6/18
4:40 pm-10:50 pm
1 stop6h 10m
Lambert-St Louis
Fri 6/19
6:30 pm-11:30 pm
1 stop5h 00m
$317
Showing 1-10 of 46 resultsSorted by cheapest first
Best time to book a flight from Iowa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
OMA-STL
DSM-STL
LSE-STL
ALO-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to St. Louis
USIA-STL
OMA-STL
DSM-STL
LSE-STL
ALO-STL
How much does it cost to fly round-trip from Iowa to St. Louis?
Related info for your journey
Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Iowa to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Iowa and St. Louis flights
Browse other Iowa and St. Louis flight options. Last updated on May 10, 2026.
Popular flight searches
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 10, 2026.
Iowa to St. Louis flights
Consider these flights traveling from Iowa to St. Louis.
Top 2 airlines flying from Iowa to St. Louis
Discover the top 2 airlines that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$253 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$398 | FlexibilityNo cancel fee | On-time71% |