$102+ Cheap flights from Iowa to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Jul 24 — Jul 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Iowa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Iowa to St. LouisExplore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Tue 8/48:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:06 pm
OMA
- STL
1 stop20h 44m
Multiple Airlines
Thu 8/276:45 pm
STL
- OMA
1 stop25h 31m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:33 pm
DSM
- STL
1 stop5h 43m
American Airlines
Wed 7/295:58 pm
STL
- DSM
1 stop6h 03m
American Airlines
Deal found 6/22![American Airlines logo]()
$263
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Thu 7/308:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Sat 7/254:57 pm
STL
- DSM
2 stops29h 50m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$267
This Mytrip deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Mon 7/278:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$269
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:55 am
DSM
- STL
1 stop5h 59m
American Airlines
Mon 8/318:07 pm
STL
- DSM
1 stop4h 13m
American Airlines
Deal found 6/19![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:20 am
DSM
- STL
1 stop4h 15m
Southwest
Wed 7/2910:15 am
STL
- DSM
2 stops12h 35m
Southwest
Deal found 6/22![Southwest logo]()
$274
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/48:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/22![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:40 pm
DSM
- STL
2 stops7h 30m
Southwest
Mon 8/318:30 am
STL
- DSM
1 stop5h 15m
Southwest
Deal found 6/19![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Sat 7/184:57 pm
STL
- DSM
2 stops29h 50m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:56 pm
DSM
- STL
1 stop5h 30m
Delta
Tue 8/1811:13 am
STL
- DSM
1 stop5h 37m
Delta
Deal found 6/19![Delta logo]()
$279
Best flights from Iowa to St. LouisDiscover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 24, 2026.
Discover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 24, 2026.
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:55 am
DSM
- STL
1 stop5h 59m
American Airlines
Mon 8/318:07 pm
STL
- DSM
1 stop4h 13m
American Airlines
Deal found 6/19![American Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:56 pm
DSM
- STL
1 stop5h 30m
Delta
Tue 8/1811:13 am
STL
- DSM
1 stop5h 37m
Delta
Deal found 6/19![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Tue 8/183:05 pm
STL
- DSM
2 stops6h 50m
Southwest
Deal found 6/19![Southwest logo]()
$286
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:13 am
DSM
- STL
1 stop7h 21m
United Airlines
Wed 9/26:00 am
STL
- DSM
1 stop4h 26m
United Airlines
Deal found 6/20![United Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:10 pm
OMA
- STL
1 stop5h 55m
Southwest
Sat 9/268:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/23![Southwest logo]()
$292
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:05 pm
OMA
- STL
1 stop6h 35m
Southwest
Wed 9/92:50 pm
STL
- OMA
2 stops6h 00m
Southwest
Deal found 6/21![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:54 am
DSM
- STL
1 stop5h 52m
Delta
Sat 7/115:36 pm
STL
- DSM
1 stop3h 32m
Delta
Deal found 6/22![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:55 pm
OMA
- STL
1 stop6h 51m
United Airlines
Wed 8/128:00 am
STL
- OMA
1 stop6h 04m
United Airlines
Deal found 6/23![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:40 pm
DSM
- STL
1 stop6h 15m
Southwest
Sat 7/254:45 pm
STL
- DSM
1 stop5h 15m
Southwest
Deal found 6/21![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:57 pm
LSE
- STL
1 stop6h 19m
American Airlines
Tue 7/285:58 pm
STL
- LSE
1 stop6h 01m
American Airlines
Deal found 6/20![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:40 pm
DSM
- STL
1 stop6h 15m
Southwest
Mon 8/106:15 pm
STL
- DSM
1 stop3h 55m
Southwest
Deal found 6/19![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:10 am
OMA
- STL
1 stop4h 21m
Delta
Sun 10/46:15 am
STL
- OMA
1 stop5h 45m
Delta
Deal found 6/21![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:26 pm
ALO
- STL
1 stop17h 05m
American Airlines
Sat 8/18:06 pm
STL
- ALO
1 stop18h 47m
American Airlines
Deal found 6/22![American Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:30 pm
DSM
- STL
2 stops8h 05m
Southwest
Sun 10/185:40 am
STL
- DSM
1 stop5h 45m
Southwest
Deal found 6/21![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:45 pm
LSE
- STL
1 stop26h 28m
United Airlines
Sat 11/146:00 am
STL
- LSE
1 stop12h 03m
United Airlines
Deal found 6/21![United Airlines logo]()
$474
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:05 pm
OMA
- STL
1 stop7h 30m
Southwest
Tue 10/138:30 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 6/22![Southwest logo]()
$333
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:23 pm
ALO
- STL
1 stop8h 53m
American Airlines
Thu 8/66:00 am
STL
- ALO
1 stop18h 22m
American Airlines
Deal found 6/22![American Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:25 am
OMA
- STL
1 stop3h 45m
Southwest
Wed 7/298:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/19![Southwest logo]()
$333
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:23 pm
ALO
- STL
1 stop22h 30m
American Airlines
Tue 8/48:41 pm
STL
- ALO
1 stop18h 11m
American Airlines
Deal found 6/22![American Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:25 pm
OMA
- STL
2 stops6h 25m
Southwest
Tue 9/228:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/22![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:56 am
LSE
- STL
1 stop5h 50m
American Airlines
Mon 7/67:56 pm
STL
- LSE
1 stop4h 03m
American Airlines
Deal found 6/19![American Airlines logo]()
$504
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:25 pm
OMA
- STL
1 stop7h 20m
Southwest
Thu 7/305:50 am
STL
- OMA
2 stops9h 50m
Southwest
Deal found 6/20![Southwest logo]()
$348
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:01 pm
LSE
- STL
1 stop4h 22m
American Airlines
Sun 8/308:07 pm
STL
- LSE
1 stop4h 15m
American Airlines
Deal found 6/22![American Airlines logo]()
$512
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:40 pm
DSM
- STL
2 stops6h 10m
Southwest
Fri 7/245:35 am
STL
- DSM
1 stop7h 15m
Southwest
Deal found 6/19![Southwest logo]()
$350
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:06 am
ALO
- STL
1 stop19h 10m
American Airlines
Fri 8/78:07 pm
STL
- ALO
1 stop4h 15m
American Airlines
Deal found 6/22![American Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:06 am
ALO
- STL
1 stop3h 25m
American Airlines
Sat 7/115:19 pm
STL
- ALO
1 stop7h 03m
American Airlines
Deal found 6/22![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:23 pm
ALO
- STL
1 stop17h 08m
American Airlines
Mon 8/37:56 pm
STL
- ALO
1 stop4h 33m
American Airlines
Deal found 6/22![American Airlines logo]()
$632
Last-minute flights from Iowa to St. LouisDiscover last-minute flight deals from Iowa to St. Louis. Data last updated June 24, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to St. Louis. Data last updated June 24, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Wed 7/88:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/21![Frontier logo]()
$301
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Thu 7/98:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Sat 7/184:57 pm
STL
- DSM
2 stops29h 50m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$278
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:00 am
OMA
- STL
1 stop6h 53m
American Airlines
Wed 7/159:44 am
STL
- OMA
1 stop6h 34m
American Airlines
Deal found 6/20![American Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Sat 7/254:57 pm
STL
- DSM
2 stops29h 50m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$267
This Mytrip deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Mon 7/278:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$269
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:40 pm
DSM
- STL
1 stop6h 15m
Southwest
Sat 7/254:45 pm
STL
- DSM
1 stop5h 15m
Southwest
Deal found 6/21![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:33 pm
DSM
- STL
1 stop5h 43m
American Airlines
Wed 7/295:58 pm
STL
- DSM
1 stop6h 03m
American Airlines
Deal found 6/22![American Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:20 am
DSM
- STL
1 stop4h 15m
Southwest
Wed 7/2910:15 am
STL
- DSM
2 stops12h 35m
Southwest
Deal found 6/22![Southwest logo]()
$274
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Thu 7/308:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$264
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Tue 8/48:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$232
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/48:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/22![Southwest logo]()
$275
One-way flights from Iowa to St. LouisSearch for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 24, 2026.
Search for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/19![Frontier logo]()
$102
This Orbitz deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Deal found 6/20![Frontier logo]()
$115
This Frontier deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:18 pm
OMA
- STL
1 stop4h 55m
Frontier
Deal found 6/20![Frontier logo]()
$122
This Frontier deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:18 pm
OMA
- STL
1 stop4h 55m
Frontier
Deal found 6/23![Frontier logo]()
$126
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:00 am
DSM
- STL
1 stop4h 11m
United Airlines
Deal found 6/21![United Airlines logo]()
$132
This Frontier deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:18 pm
OMA
- STL
1 stop4h 55m
Frontier
Deal found 6/22![Frontier logo]()
$135
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/22![Frontier logo]()
$137
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:20 am
DSM
- STL
2 stops9h 30m
Southwest
Deal found 6/23![Southwest logo]()
$137
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/20![Southwest logo]()
$138
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
DSM
- STL
1 stop4h 50m
Southwest
Deal found 6/23![Southwest logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:55 pm
DSM
- STL
2 stops27h 27m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$142
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:10 am
OMA
- STL
1 stop4h 13m
Delta
Deal found 6/22![Delta logo]()
$143
Find flight deals from Iowa to St. Louis
Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated June 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $232 (Booking.com) |
One-way from | $102 (Kiwi.com) |
Popular in | July |
Cheapest in | May |
Average price | $371 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 8/26
6:55 am-12:54 pm
1 stop5h 59m
Lambert-St Louis
Mon 8/31
8:07 pm-12:20 am
1 stop4h 13m
$271
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 8/10
5:56 pm-11:26 pm
1 stop5h 30m
Lambert-St Louis
Tue 8/18
11:13 am-4:50 pm
1 stop5h 37m
$279
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 8/10
3:50 pm-10:05 pm
1 stop6h 15m
Lambert-St Louis
Tue 8/18
3:05 pm-9:55 pm
2 stops6h 50m
$286
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Thu 9/24
1:10 pm-7:05 pm
1 stop5h 55m
Lambert-St Louis
Sat 9/26
8:30 am-9:45 am
Nonstop1h 15m
$292
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Tue 9/8
3:05 pm-9:40 pm
1 stop6h 35m
Lambert-St Louis
Wed 9/9
2:50 pm-8:50 pm
2 stops6h 00m
$300
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 7/20
4:40 pm-10:55 pm
1 stop6h 15m
Lambert-St Louis
Sat 7/25
4:45 pm-10:00 pm
1 stop5h 15m
$304
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 8/3
4:40 pm-10:55 pm
1 stop6h 15m
Lambert-St Louis
Mon 8/10
6:15 pm-10:10 pm
1 stop3h 55m
$314
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 10/15
4:30 pm-12:35 am
2 stops8h 05m
Lambert-St Louis
Sun 10/18
5:40 am-11:25 am
1 stop5h 45m
$317
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 9/1
9:13 am-4:34 pm
1 stop7h 21m
Lambert-St Louis
Wed 9/2
6:00 am-10:26 am
1 stop4h 26m
$333
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Mon 10/12
5:05 pm-12:35 am
1 stop7h 30m
Lambert-St Louis
Tue 10/13
8:30 am-9:50 am
Nonstop1h 20m
$333
Showing 1-10 of 46 resultsSorted by cheapest first
Best time to book a flight from Iowa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
DSM-STL
OMA-STL
LSE-STL
ALO-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to St. Louis
USIA-STL
DSM-STL
OMA-STL
LSE-STL
ALO-STL
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
St. Louis flight routes
Top destinations
Alternative routes for Iowa to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to St. Louis by cabin class
Find flights from Iowa to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and St. Louis flights
Browse other Iowa and St. Louis flight options. Last updated on June 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 24, 2026.
Iowa to St. Louis flights
Consider these flights traveling from Iowa to St. Louis.
Top 2 airlines flying from Iowa to St. Louis
Discover the top 2 airlines that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$398 | FlexibilityNo cancel fee | On-time71% |