$250+ Cheap flights from La Crosse to St. Louis (LSE - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — STL
Oct 7 — Oct 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from La Crosse to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from La Crosse to St. LouisExplore the most affordable flight options available from La Crosse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from La Crosse to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:53 am -
1 stop4h 25m
Sat 9/265:00 am -
1 stop6h 22m
Deal found 9/6![American Airlines logo]()
$508
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:53 am -
1 stop4h 25m
Sun 9/137:27 am -
1 stop3h 55m
Deal found 9/2![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:14 pm -
1 stop3h 43m
Sun 9/68:07 pm -
1 stop4h 15m
Deal found 9/5![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:49 pm -
1 stop9h 33m
Sun 12/206:00 am -
1 stop18h 30m
Deal found 9/4![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:00 am -
1 stop6h 55m
Mon 11/308:12 pm -
1 stop4h 08m
Deal found 9/3![American Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:54 am -
2 stops7h 09m
Sun 9/135:00 am -
1 stop6h 22m
Deal found 9/2![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:19 pm -
1 stop4h 01m
Mon 9/78:07 pm -
1 stop4h 15m
Deal found 9/2![American Airlines logo]()
$610
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:24 pm -
1 stop4h 19m
Wed 11/185:29 pm -
1 stop6h 49m
Deal found 9/6![American Airlines logo]()
$643
Best flights from La Crosse to St. LouisDiscover carefully curated flight deals from La Crosse to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from La Crosse to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:53 am -
1 stop4h 25m
Sun 9/137:27 am -
1 stop3h 55m
Deal found 9/2![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:26 pm -
2 stops10h 16m
Sat 9/2611:01 am -
1 stop5h 51m
Deal found 9/6![American Airlines logo]()
$546
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:00 am -
1 stop6h 55m
Mon 11/308:12 pm -
1 stop4h 08m
Deal found 9/3![American Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:24 pm -
2 stops11h 34m
Wed 11/186:00 am -
1 stop5h 53m
Deal found 9/6![American Airlines logo]()
$754
Last-minute flights from La Crosse to St. LouisDiscover last-minute flight deals from La Crosse to St. Louis. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to St. Louis. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:19 pm -
1 stop4h 01m
Mon 9/78:07 pm -
1 stop4h 15m
Deal found 9/2![American Airlines logo]()
$610
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:14 pm -
1 stop3h 43m
Sun 9/68:07 pm -
1 stop4h 15m
Deal found 9/5![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:02 am -
2 stops11h 32m
Mon 9/76:54 am -
2 stops9h 56m
Deal found 9/3![American Airlines logo]()
$953
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:54 am -
2 stops7h 09m
Sun 9/135:00 am -
1 stop6h 22m
Deal found 9/2![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:53 am -
1 stop4h 25m
Sun 9/137:27 am -
1 stop3h 55m
Deal found 9/2![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:53 am -
1 stop4h 25m
Sat 9/265:00 am -
1 stop6h 22m
Deal found 9/6![American Airlines logo]()
$508
One-way flights from La Crosse to St. LouisSearch for one-way flight options from La Crosse to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from La Crosse to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:06 pm -
2 stops51h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$250
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
1 stop26h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:50 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:28 pm -
3 stops23h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$831
Find flight deals from La Crosse to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $508 (American Airlines) |
One-way from | $250 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from La Crosse to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Fri 10/9
8:06 pm-11:13 pm
3 stops51h 07m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$316
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Fri 10/9
7:04 am-12:35 pm
1 stop29h 31m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$378
Quickest round-trip
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Thu 9/10
5:53 am-10:18 am
1 stop4h 25m
Lambert-St Louis
Sun 9/13
7:27 am-11:22 am
1 stop3h 55m
$514
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Tue 9/22
12:26 pm-10:42 pm
2 stops10h 16m
Lambert-St Louis
Sat 9/26
11:01 am-4:52 pm
1 stop5h 51m
$546
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Sat 11/28
6:00 am-12:55 pm
1 stop6h 55m
Lambert-St Louis
Mon 11/30
8:12 pm-12:20 am
1 stop4h 08m
$595
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Sun 11/29
6:50 pm-10:34 am
1 stop15h 44m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$627
La CrosseSt. Louis
LSE La Crosse - STL Lambert-St Louis
LSESTL
La Crosse
Fri 11/13
12:24 pm-11:58 pm
2 stops11h 34m
Lambert-St Louis
Wed 11/18
6:00 am-11:53 am
1 stop5h 53m
$754
Sorted by cheapest first
Compare providers for flights from La Crosse to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on La Crosse-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from La Crosse with our price prediction graph.
LSE-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from La Crosse to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from La Crosse
Popular flights
St. Louis flight routes