$454+ Cheap flights from La Crosse to Columbia, MO (LSE - COU)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — COU
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to Columbia
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Best
Last-minute
One-way
Cheapest flights from La Crosse to ColumbiaExplore the most affordable flight options available from La Crosse to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from La Crosse to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:25 pm
LSE
- COU
1 stop3h 59m
American Airlines
Tue 6/306:00 am
COU
- LSE
1 stop5h 22m
American Airlines
Deal found 6/7![American Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:41 pm
LSE
- COU
1 stop7h 39m
United Airlines
Sat 12/125:00 am
COU
- LSE
1 stop8h 05m
United Airlines
Deal found 6/4![United Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:52 am
LSE
- COU
1 stop6h 25m
American Airlines
Fri 6/267:39 pm
COU
- LSE
2 stops15h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$864
Best flights from La Crosse to ColumbiaDiscover carefully curated flight deals from La Crosse to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from La Crosse to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
LSE
- COU
1 stop4h 06m
American Airlines
Tue 6/306:00 am
COU
- LSE
1 stop5h 22m
American Airlines
Deal found 6/5![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:52 am
LSE
- COU
2 stops10h 54m
American Airlines
Fri 6/267:39 pm
COU
- LSE
2 stops15h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$869
Last-minute flights from La Crosse to ColumbiaDiscover last-minute flight deals from La Crosse to Columbia. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to Columbia. Data last updated June 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:52 am
LSE
- COU
1 stop6h 25m
American Airlines
Fri 6/267:39 pm
COU
- LSE
2 stops15h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$864
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:25 pm
LSE
- COU
1 stop3h 59m
American Airlines
Tue 6/306:00 am
COU
- LSE
1 stop5h 22m
American Airlines
Deal found 6/7![American Airlines logo]()
$488
One-way flights from La Crosse to ColumbiaSearch for one-way flight options from La Crosse to Columbia. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from La Crosse to Columbia. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:52 am
LSE
- COU
1 stop6h 25m
American Airlines
Deal found 6/9![American Airlines logo]()
$454
Find flight deals from La Crosse to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Round-trip from | $488 (American Airlines) |
|---|---|
One-way from | $454 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from La Crosse to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
La CrosseColumbia
LSE - COU
LSECOU
La Crosse
Wed 6/24
6:00 am-10:06 am
1 stop4h 06m
Columbia Regional
Tue 6/30
6:00 am-11:22 am
1 stop5h 22m
$488
La CrosseColumbia
LSE - COU
LSECOU
La Crosse
Mon 6/22
11:52 am-10:46 pm
2 stops10h 54m
Columbia Regional
Fri 6/26
7:39 pm-11:07 am
2 stops15h 28m
$869
Cheapest one-way
Quickest one-way
La CrosseColumbia
LSE - COU
LSECOU
La Crosse
Tue 6/16
11:52 am-6:17 pm
1 stop6h 25m
$454
Sorted by cheapest first
Best time to book a flight from La Crosse to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from La Crosse with our price prediction graph.
LSE-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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