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St. Louis

$49+ Cheap flights from Iowa to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Iowa to St. Louis

Cheapest flights from Iowa to St. Louis
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - STL
1 stop18h 35mFrontier
Wed 11/127:45 pmSTL - DSM
1 stop18h 11mFrontier
Deal found 10/27$120
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:46 pmOMA - STL
1 stop13h 21mFrontier
Sun 11/167:45 pmSTL - OMA
1 stop24h 21mFrontier
Deal found 10/28$178
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:58 pmDSM - STL
1 stop14h 16mFrontier
Fri 12/197:43 pmSTL - DSM
1 stop24h 01mFrontier
Deal found 10/28$196
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:51 pmOMA - STL
1 stop12h 16mFrontier
Sun 11/97:45 pmSTL - OMA
1 stop24h 21mFrontier
Deal found 10/28$214
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:46 pmOMA - STL
1 stop13h 21mFrontier
Sun 11/27:45 pmSTL - OMA
1 stop24h 21mFrontier
Deal found 10/29$238
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:23 amDSM - STL
1 stop6h 33mDelta
Sun 12/76:00 amSTL - DSM
1 stop4h 38mDelta
Deal found 10/28$243
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:28 pmDSM - STL
2 stops14h 46mMultiple Airlines
Fri 12/197:43 pmSTL - DSM
1 stop24h 01mMultiple Airlines
Deal found 10/28$251
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:23 pmOMA - STL
1 stop5h 15mAmerican Airlines
Mon 12/85:30 pmSTL - OMA
1 stop5h 56mAmerican Airlines
Deal found 10/30$257
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:51 pmOMA - STL
1 stop12h 16mFrontier
Sat 11/18:40 pmSTL - OMA
1 stop23h 11mFrontier
Deal found 10/28$261
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:03 pmOMA - STL
1 stop7h 25mAmerican Airlines
Sat 12/135:30 pmSTL - OMA
1 stop5h 56mAmerican Airlines
Deal found 10/30$274
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - STL
1 stop18h 35mMultiple Airlines
Wed 11/127:45 pmSTL - DSM
2 stops25h 27mMultiple Airlines
Deal found 10/27$278
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amOMA - STL
Nonstop1h 25mSouthwest
Mon 12/88:25 pmSTL - OMA
Nonstop1h 20mSouthwest
Deal found 10/30$279

Cheap flight deals from Iowa to St. Louis

Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$120
(Mytrip)

One-way from

$49
(Southwest)

Popular in

July

Cheapest in

September

Average price

$230

Good round-trip deal

$105 or less

Good one-way deal

$163 or less
Provider with most accurate pricing for Des Moines-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Lambert-St Louis flights.
Search Deals
From Iowa to Lambert-St Louis
Search Deals
One-way flight from Iowa to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Iowa to Lambert-St Louis.
Search Deals
Price to beat on a one-way flight from Iowa to Lambert-St Louis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.

Fly from

Iowa

Fly to

St. Louis

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 3/3

5:15 pm-11:40 pm

1 stop6h 25m

Lambert-St Louis

Wed 3/4

6:30 am-10:22 am

1 stop3h 52m

$157

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Thu 11/13

7:46 pm-9:07 am

1 stop13h 21m

Lambert-St Louis

Sun 11/16

7:45 pm-8:06 pm

1 stop24h 21m

$178

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 12/12

7:58 pm-10:14 am

1 stop14h 16m

Lambert-St Louis

Fri 12/19

7:43 pm-7:44 pm

1 stop24h 01m

$196

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 12/4

11:23 am-5:56 pm

1 stop6h 33m

Lambert-St Louis

Sun 12/7

6:00 am-10:38 am

1 stop4h 38m

$243

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Thu 12/11

2:03 pm-9:28 pm

1 stop7h 25m

Lambert-St Louis

Sat 12/13

5:30 pm-11:26 pm

1 stop5h 56m

$274

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Thu 12/4

6:00 am-7:25 am

Nonstop1h 25m

Lambert-St Louis

Mon 12/8

8:25 pm-9:45 pm

Nonstop1h 20m

$279

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 12/12

7:28 pm-10:14 am

2 stops14h 46m

Lambert-St Louis

Fri 12/19

9:50 am-2:57 pm

2 stops29h 07m

$307

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Thu 12/18

9:35 am-5:10 pm

1 stop7h 35m

Lambert-St Louis

Sun 12/21

7:00 am-2:45 pm

1 stop7h 45m

$314

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 11/24

1:53 pm-11:56 pm

1 stop10h 03m

Lambert-St Louis

Mon 12/1

7:58 pm-11:44 pm

1 stop3h 46m

$314

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Thu 2/19

7:00 am-1:49 pm

1 stop6h 49m

Lambert-St Louis

Mon 2/23

2:19 pm-6:59 pm

1 stop4h 40m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 37 results
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Best time to book a flight from Iowa to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to St. Louis

What is the cheapest month to book a flight from Iowa to St. Louis?

Currently, October is the cheapest month in which you can book a flight from Iowa to St. Louis (average of $93). Flying from Iowa to St. Louis in December is currently the most expensive (average of $298). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to STL?

Find hourly flight availability from Iowa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 25% on flights from Iowa to St. Louis by exploring options for tickets in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Iowa?

    Lambert-St Louis (STL) is the airport you will fly into if you book a flight from Iowa to St. Louis. It is only a 12.7 mi journey from Lambert-St Louis (STL) to St. Louis’s city center.

  • How popular is this Iowa to St. Louis flight route?

    Within the past month, 30 users have taken a look at flights from Iowa to Lambert-St Louis.

  • How long is the flight from Iowa to St. Louis?

    A quick flight from Iowa to St. Louis can take about 6h 25m. Delta provides one of the quickest options available for as low as $157. Airlines will cover a distance of 259 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to St. Louis?

    The most popular flight routes from Iowa to St. Louis are Omaha Eppley Airfield - Lambert-St Louis, Des Moines - Lambert-St Louis and La Crosse - Lambert-St Louis.

  • What are the cheapest flights from Iowa to St. Louis?

    On average you can expect to pay $285 for a flight from Iowa to St. Louis. The cheapest flight overall is $124 while the most popular route, (Omaha Eppley Airfield - Lambert-St Louis) is currently priced at $194.

  • Can I find deals for flights from Iowa to St. Louis that include hotel bookings?

    Yes. In addition to deals on Iowa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to St. Louis.

  • Can I find deals for business class flights from Iowa to St. Louis?

    Yes. Cheapflights offers flight deals from Iowa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to St. Louis?

    Currently, October is the cheapest month in which you can book a flight from Iowa to St. Louis (average of $93). Flying from Iowa to St. Louis in December is currently the most expensive (average of $298). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Top 2 airlines flying from Iowa to St. Louis

Discover the top 2 airlines that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$61Average$85FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$97Average$275FlexibilityNo cancel feeOn-time63%

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