$90+ Cheap flights from Iowa to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Apr 24 — May 11
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to St. Louis
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Cheapest flights from Iowa to St. LouisExplore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 am
DSM
- STL
1 stop4h 00m
Southwest
Tue 4/283:55 pm
STL
- DSM
1 stop5h 20m
Southwest
Deal found 3/23![Southwest logo]()
$202
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:09 am
DSM
- STL
1 stop5h 32m
American Airlines
Wed 5/207:05 am
STL
- DSM
1 stop6h 41m
American Airlines
Deal found 3/23![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 am
DSM
- STL
1 stop4h 00m
Southwest
Thu 6/46:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 3/23![Southwest logo]()
$230
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:21 pm
DSM
- STL
1 stop6h 31m
United Airlines
Tue 4/289:10 am
STL
- DSM
1 stop5h 15m
United Airlines
Deal found 3/25![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
DSM
- STL
1 stop4h 47m
Delta
Sat 5/166:45 am
STL
- DSM
2 stops8h 59m
Delta
Deal found 3/23![Delta logo]()
$244
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:35 am
DSM
- STL
1 stop4h 55m
Southwest
Sat 5/165:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 3/23![Southwest logo]()
$245
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 5/138:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/22![Southwest logo]()
$247
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Tue 4/282:30 pm
STL
- DSM
2 stops7h 40m
Southwest
Deal found 3/25![Southwest logo]()
$248
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Deal found 3/22![Frontier logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:22 pm
OMA
- STL
1 stop5h 51m
United Airlines
Tue 4/287:45 am
STL
- OMA
1 stop6h 35m
United Airlines
Deal found 3/24![United Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Thu 5/141:45 pm
STL
- DSM
1 stop9h 20m
Southwest
Deal found 3/23![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 4/288:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/24![Southwest logo]()
$254
Best flights from Iowa to St. LouisDiscover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
Discover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 25, 2026.
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 am
DSM
- STL
1 stop4h 00m
Southwest
Tue 4/283:55 pm
STL
- DSM
1 stop5h 20m
Southwest
Deal found 3/23![Southwest logo]()
$202
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Deal found 3/22![Frontier logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:22 pm
OMA
- STL
1 stop5h 51m
United Airlines
Tue 4/287:45 am
STL
- OMA
1 stop6h 35m
United Airlines
Deal found 3/24![United Airlines logo]()
$250
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:55 am
OMA
- STL
1 stop4h 37m
Delta
Sat 5/212:23 pm
STL
- OMA
1 stop4h 39m
Delta
Deal found 3/25![Delta logo]()
$295
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:37 pm
LSE
- STL
1 stop3h 40m
American Airlines
Mon 4/205:51 am
STL
- LSE
1 stop3h 44m
American Airlines
Deal found 3/23![American Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Tue 4/282:30 pm
STL
- DSM
2 stops7h 40m
Southwest
Deal found 3/25![Southwest logo]()
$248
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:17 pm
DSM
- STL
1 stop6h 40m
United Airlines
Wed 6/36:00 am
STL
- DSM
1 stop6h 30m
United Airlines
Deal found 3/24![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 4/288:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/24![Southwest logo]()
$254
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:04 pm
DSM
- STL
1 stop3h 42m
Delta
Sun 5/316:21 am
STL
- DSM
1 stop6h 03m
Delta
Deal found 3/25![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:03 pm
DSM
- STL
1 stop3h 43m
American Airlines
Thu 4/235:20 am
STL
- DSM
1 stop6h 06m
American Airlines
Deal found 3/20![American Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:37 pm
LSE
- STL
1 stop3h 40m
American Airlines
Sun 4/128:03 pm
STL
- LSE
1 stop3h 51m
American Airlines
Deal found 3/24![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:50 pm
OMA
- STL
1 stop6h 53m
United Airlines
Wed 5/68:21 am
STL
- OMA
1 stop3h 58m
United Airlines
Deal found 3/23![United Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:55 am
OMA
- STL
1 stop4h 44m
Delta
Mon 5/45:35 pm
STL
- OMA
1 stop5h 14m
Delta
Deal found 3/20![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Sat 4/1810:35 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/20![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:16 pm
DSM
- STL
1 stop5h 17m
American Airlines
Wed 5/137:05 am
STL
- DSM
1 stop4h 25m
American Airlines
Deal found 3/22![American Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:25 am
DSM
- STL
2 stops9h 30m
Southwest
Sun 5/314:20 pm
STL
- DSM
2 stops7h 00m
Southwest
Deal found 3/22![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Sun 5/105:25 am
STL
- DSM
1 stop6h 00m
Southwest
Deal found 3/22![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:40 pm
DSM
- STL
1 stop6h 10m
Southwest
Tue 6/95:55 pm
STL
- DSM
1 stop4h 50m
Southwest
Deal found 3/21![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Mon 5/189:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/24![Southwest logo]()
$346
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:20 pm
OMA
- STL
1 stop4h 30m
Southwest
Sun 5/33:40 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 3/24![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:40 am
ALO
- STL
1 stop6h 07m
American Airlines
Sat 4/118:57 am
STL
- ALO
1 stop4h 56m
American Airlines
Deal found 3/23![American Airlines logo]()
$545
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:00 pm
OMA
- STL
1 stop9h 55m
Southwest
Sun 6/149:45 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 3/23![Southwest logo]()
$365
Last-minute flights from Iowa to St. LouisDiscover last-minute flight deals from Iowa to St. Louis. Data last updated March 25, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to St. Louis. Data last updated March 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:01 pm
DSM
- STL
1 stop6h 45m
American Airlines
Tue 4/215:20 am
STL
- DSM
1 stop6h 06m
American Airlines
Deal found 3/25![American Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:17 am
OMA
- STL
1 stop6h 20m
American Airlines
Wed 4/158:03 pm
STL
- OMA
1 stop3h 56m
American Airlines
Deal found 3/23![American Airlines logo]()
$255
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:25 am
OMA
- STL
1 stop4h 40m
Southwest
Wed 4/158:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/23![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:25 am
OMA
- STL
1 stop8h 08m
American Airlines
Thu 4/165:51 am
STL
- OMA
1 stop5h 52m
American Airlines
Deal found 3/23![American Airlines logo]()
$280
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Deal found 3/22![Frontier logo]()
$249
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 am
DSM
- STL
1 stop4h 00m
Southwest
Tue 4/283:55 pm
STL
- DSM
1 stop5h 20m
Southwest
Deal found 3/23![Southwest logo]()
$202
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:22 pm
OMA
- STL
1 stop5h 51m
United Airlines
Tue 4/287:45 am
STL
- OMA
1 stop6h 35m
United Airlines
Deal found 3/24![United Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 4/288:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/24![Southwest logo]()
$254
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:21 pm
DSM
- STL
1 stop6h 31m
United Airlines
Tue 4/289:10 am
STL
- DSM
1 stop5h 15m
United Airlines
Deal found 3/25![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Tue 4/282:30 pm
STL
- DSM
2 stops7h 40m
Southwest
Deal found 3/25![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:03 pm
DSM
- STL
1 stop3h 43m
American Airlines
Mon 4/275:51 am
STL
- DSM
1 stop4h 35m
American Airlines
Deal found 3/25![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Mon 4/2710:15 am
STL
- DSM
2 stops12h 50m
Southwest
Deal found 3/25![Southwest logo]()
$277
One-way flights from Iowa to St. LouisSearch for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
Search for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 25, 2026.
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Deal found 3/20![Frontier logo]()
$90
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:41 pm
DSM
- STL
1 stop5h 18m
Delta
Deal found 3/24![Delta logo]()
$100
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:44 pm
DSM
- STL
1 stop6h 35m
Delta
Deal found 3/24![Delta logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Deal found 3/24![Frontier logo]()
$105
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
DSM
- STL
1 stop4h 00m
Southwest
Deal found 3/22![Southwest logo]()
$105
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:10 am
DSM
- STL
2 stops9h 22m
Delta
Deal found 3/24![Delta logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/25![Frontier logo]()
$109
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/222:16 pm
DSM
- STL
1 stop5h 07m
Frontier
Deal found 3/25![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Deal found 3/23![Frontier logo]()
$116
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:44 pm
DSM
- STL
1 stop4h 27m
Delta
Deal found 3/24![Delta logo]()
$120
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:42 am
OMA
- STL
1 stop5h 49m
Delta
Deal found 3/24![Delta logo]()
$123
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:23 pm
DSM
- STL
1 stop6h 50m
Delta
Deal found 3/24![Delta logo]()
$123
Find flight deals from Iowa to St. Louis
Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated March 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $202 (Southwest) |
One-way from | $90 (Expedia) |
Popular in | July |
Cheapest in | September |
Average price | $243 |
Good round-trip deal | $105 or less |
Good one-way deal | $261 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 4/21
5:30 am-9:30 am
1 stop4h 00m
Lambert-St Louis
Tue 4/28
3:55 pm-9:15 pm
1 stop5h 20m
$202
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Fri 4/24
4:20 pm-10:45 pm
1 stop6h 25m
Lambert-St Louis
Tue 4/28
2:30 pm-10:10 pm
2 stops7h 40m
$248
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Fri 4/17
2:04 pm-7:21 pm
1 stop5h 17m
Lambert-St Louis
Thu 4/23
8:06 pm-1:09 pm
1 stop17h 03m
$249
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Tue 4/21
3:22 pm-9:13 pm
1 stop5h 51m
Lambert-St Louis
Tue 4/28
7:45 am-2:20 pm
1 stop6h 35m
$250
Quickest round-trip
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Tue 4/21
4:45 pm-6:00 pm
Nonstop1h 15m
Lambert-St Louis
Tue 4/28
8:50 pm-10:10 pm
Nonstop1h 20m
$254
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 6/2
5:17 pm-11:57 pm
1 stop6h 40m
Lambert-St Louis
Wed 6/3
6:00 am-12:30 pm
1 stop6h 30m
$269
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Thu 4/30
6:55 am-11:32 am
1 stop4h 37m
Lambert-St Louis
Sat 5/2
12:23 pm-5:02 pm
1 stop4h 39m
$295
La CrosseSt. Louis
LSE - STL
LSESTL
La Crosse
Wed 4/15
6:37 pm-10:17 pm
1 stop3h 40m
Lambert-St Louis
Mon 4/20
5:51 am-9:35 am
1 stop3h 44m
$298
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Fri 5/29
1:04 pm-4:46 pm
1 stop3h 42m
Lambert-St Louis
Sun 5/31
6:21 am-12:24 pm
1 stop6h 03m
$298
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 4/16
8:03 pm-11:46 pm
1 stop3h 43m
Lambert-St Louis
Thu 4/23
5:20 am-11:26 am
1 stop6h 06m
$307
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from Iowa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
DSM-STL
OMA-STL
LSE-STL
ALO-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to St. Louis
USIA-STL
DSM-STL
OMA-STL
LSE-STL
ALO-STL
How much does it cost to fly round-trip from Iowa to St. Louis?
Related info for your journey
Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Alternative routes for Iowa to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Iowa to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and St. Louis flights
Browse other Iowa and St. Louis flight options. Last updated on March 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 25, 2026.
Iowa to St. Louis flights
Consider these flights traveling from Iowa to St. Louis.
Top airline flying from Iowa to St. Louis
Discover the top airline that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$253 | FlexibilityNo cancel fee | On-time63% |