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St. Louis

$59+ Cheap flights from Iowa to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Iowa to St. Louis

Cheapest flights from Iowa to St. Louis
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:20 pm
DSM
-
STL
Nonstop1h 15m
Southwest
Tue 3/38:00 pm
STL
-
DSM
Nonstop1h 10m
Southwest
Deal found 1/27$97
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:30 am
DSM
-
STL
1 stop6h 10m
Southwest
Wed 3/114:00 pm
STL
-
DSM
1 stop6h 05m
Southwest
Deal found 1/28$117
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:20 am
DSM
-
STL
Nonstop1h 20m
Southwest
Tue 2/248:00 pm
STL
-
DSM
Nonstop1h 10m
Southwest
Deal found 1/28$134
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:57 am
DSM
-
STL
1 stop5h 48m
Delta
Tue 3/36:00 am
STL
-
DSM
1 stop5h 19m
Delta
Deal found 1/27$157
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:44 pm
DSM
-
STL
1 stop4h 04m
American Airlines
Tue 2/245:12 am
STL
-
DSM
1 stop5h 22m
American Airlines
Deal found 1/28$175
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:15 pm
DSM
-
STL
1 stop6h 21m
Delta
Mon 2/236:10 am
STL
-
DSM
1 stop4h 07m
Delta
Deal found 1/26$191
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:15 pm
DSM
-
STL
Nonstop1h 05m
Southwest
Tue 3/310:15 am
STL
-
DSM
Nonstop1h 10m
Southwest
Deal found 1/27$213
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:03 pm
OMA
-
STL
1 stop12h 46m
Frontier
Sat 3/288:12 pm
STL
-
OMA
1 stop24h 06m
Frontier
Deal found 1/27$235
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1211:32 am
OMA
-
STL
1 stop25h 37m
Frontier
Sat 2/142:51 pm
STL
-
OMA
1 stop21h 57m
Frontier
Deal found 1/28$237
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:18 pm
OMA
-
STL
1 stop4h 30m
American Airlines
Wed 3/46:00 am
STL
-
OMA
1 stop5h 46m
American Airlines
Deal found 1/28$265
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/97:46 pm
OMA
-
STL
1 stop26h 41m
Multiple Airlines
Fri 2/208:20 pm
STL
-
OMA
2 stops40h 28m
Multiple Airlines
Deal found 1/27$271
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/115:00 pm
OMA
-
STL
2 stops30h 59m
Frontier
Sat 2/142:51 pm
STL
-
OMA
1 stop21h 57m
Frontier
Deal found 1/28$273

Find flight deals from Iowa to St. Louis

Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$97
(Southwest)

One-way from

$59
(Southwest)

Popular in

July

Cheapest in

September

Average price

$467

Good round-trip deal

$105 or less

Good one-way deal

$187 or less
Provider with most accurate pricing for Des Moines-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Lambert-St Louis flights.
Search Deals
From Iowa to Lambert-St Louis
Search Deals
One-way flight from Iowa to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Iowa to Lambert-St Louis.
Search Deals
Price to beat on a one-way flight from Iowa to Lambert-St Louis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.

Fly from

Iowa

Fly to

St. Louis

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 2/24

3:20 pm-4:35 pm

Nonstop1h 15m

Lambert-St Louis

Tue 3/3

8:00 pm-9:10 pm

Nonstop1h 10m

$97

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 3/10

1:55 pm-9:35 pm

1 stop7h 40m

Lambert-St Louis

Wed 3/11

4:00 pm-10:05 pm

1 stop6h 05m

$117

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 2/23

5:20 am-6:40 am

Nonstop1h 20m

Lambert-St Louis

Tue 2/24

8:00 pm-9:10 pm

Nonstop1h 10m

$134

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 2/24

10:57 am-8:43 pm

2 stops9h 46m

Lambert-St Louis

Tue 3/3

3:40 pm-9:20 pm

1 stop5h 40m

$162

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 2/23

7:44 pm-11:48 pm

1 stop4h 04m

Lambert-St Louis

Tue 2/24

5:12 am-10:34 am

1 stop5h 22m

$175

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 2/18

5:15 pm-11:36 pm

1 stop6h 21m

Lambert-St Louis

Mon 2/23

6:10 am-10:17 am

1 stop4h 07m

$191

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sun 3/1

6:10 am-2:15 pm

1 stop8h 05m

Lambert-St Louis

Tue 3/3

10:15 am-11:25 am

Nonstop1h 10m

$213

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Thu 3/26

9:03 pm-9:49 am

1 stop12h 46m

Lambert-St Louis

Sat 3/28

8:12 pm-8:18 pm

1 stop24h 06m

$235

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Sat 2/21

8:00 am-2:29 pm

1 stop6h 29m

Lambert-St Louis

Tue 2/24

11:25 am-5:38 pm

1 stop6h 13m

$277

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Wed 2/25

3:55 pm-5:10 pm

Nonstop1h 15m

Lambert-St Louis

Wed 3/4

10:15 am-11:35 am

Nonstop1h 20m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 37 results
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Best time to book a flight from Iowa to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to St. Louis

What is the cheapest time of day to fly from IA to STL?

Find hourly flight availability from Iowa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

When flying from Iowa to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Iowa?

    Lambert-St Louis (STL) is the airport you will fly into if you book a flight from Iowa to St. Louis. It is only a 12.7 mi journey from Lambert-St Louis (STL) to St. Louis’s city center.

  • How popular is this Iowa to St. Louis flight route?

    Within the past month, 28 users have taken a look at flights from Iowa to Lambert-St Louis.

  • How long is the flight from Iowa to St. Louis?

    A quick flight from Iowa to St. Louis can take about 1h 15m. Southwest provides one of the quickest options available for as low as $97. Airlines will cover a distance of 259 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to St. Louis?

    The most popular flight routes from Iowa to St. Louis are Omaha Eppley Airfield - Lambert-St Louis, Des Moines - Lambert-St Louis and La Crosse - Lambert-St Louis.

  • What are the cheapest flights from Iowa to St. Louis?

    On average you can expect to pay $357 for a flight from Iowa to St. Louis. The cheapest flight overall is $98 while the most popular route, (Omaha Eppley Airfield - Lambert-St Louis) is currently priced at $265.

  • Can I find deals for flights from Iowa to St. Louis that include hotel bookings?

    Yes. In addition to deals on Iowa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to St. Louis.

  • Can I find deals for business class flights from Iowa to St. Louis?

    Yes. Cheapflights offers flight deals from Iowa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

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Alternative routes for Iowa to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Iowa to St. Louis

Discover the top airline that operate flights from Iowa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$97Average$253FlexibilityNo cancel feeOn-time63%

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