How popular is this Iowa to St. Louis flight route?

Within the past month, 33 users have taken a look at flights from Iowa to Lambert-St Louis.

How long is the flight from Iowa to St. Louis?

A quick flight from Iowa to St. Louis can take about 1h 20m. Southwest provides one of the quickest options available for as low as $133. Airlines will cover a distance of 259 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Iowa to St. Louis?

The most popular flight routes from Iowa to St. Louis are Des Moines - Lambert-St Louis, Omaha Eppley Airfield - Lambert-St Louis and La Crosse - Lambert-St Louis.

What are the cheapest flights from Iowa to St. Louis?

On average you can expect to pay $323 for a flight from Iowa to St. Louis. The cheapest flight overall is $130 while the most popular route, (Des Moines - Lambert-St Louis) is currently priced at $159.

What airport do you fly into for flights to St. Louis from Iowa?

Lambert-St Louis (STL) is the airport you will fly into if you book a flight from Iowa to St. Louis. It is only a 12.7 mi journey from Lambert-St Louis (STL) to St. Louis’s city center.

Can I find deals for flights from Iowa to St. Louis that include hotel bookings?

Yes. In addition to deals on Iowa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to St. Louis.

Can I find deals for business class flights from Iowa to St. Louis?

Yes. Cheapflights offers flight deals from Iowa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$66+ Flights from Iowa to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Iowa to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to St. Louis

Cheapest flights from Iowa to St. Louis
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/315:55 pmDSM - STL

1 stop4h 21mDelta

Wed 1/75:25 pmSTL - DSM

1 stop3h 59mDelta

Deal found 12/16

$208

Wed 12/315:55 pmDSM - STL

1 stop4h 21mDelta

Thu 1/16:05 amSTL - DSM

1 stop5h 23mDelta

Deal found 12/17

$219

Wed 12/311:09 pmDSM - STL

1 stop6h 13mAmerican Airlines

Sun 1/48:01 pmSTL - DSM

1 stop3h 29mAmerican Airlines

Deal found 12/16

$296

Mon 12/226:35 pmDSM - STL

1 stop5h 09mAmerican Airlines

Fri 1/28:01 pmSTL - DSM

1 stop3h 50mAmerican Airlines

Deal found 12/15

$404

Sat 12/209:35 amOMA - STL

1 stop7h 35mAmerican Airlines

Wed 12/317:05 amSTL - OMA

1 stop6h 03mAmerican Airlines

Deal found 12/16

$487

Wed 12/319:00 amOMA - STL

1 stop6h 03mDelta

Sun 1/46:05 amSTL - OMA

1 stop5h 34mDelta

Deal found 12/16

$515

Wed 12/175:51 pmDSM - STL

1 stop4h 56mAmerican Airlines

Tue 12/235:54 amSTL - DSM

1 stop6h 54mAmerican Airlines

Deal found 12/17

$521

Wed 12/3112:10 pmDSM - STL

2 stops8h 31mDelta

Sun 1/46:05 amSTL - DSM

1 stop5h 23mDelta

Deal found 12/16

$531

Tue 12/235:07 amDSM - STL

1 stop5h 49mAmerican Airlines

Fri 12/265:16 amSTL - DSM

1 stop5h 33mAmerican Airlines

Deal found 12/16

$555

Sat 12/203:30 pmOMA - STL

1 stop7h 26mAmerican Airlines

Sun 12/216:00 amSTL - OMA

1 stop4h 42mAmerican Airlines

Deal found 12/16

$555

Tue 12/231:25 pmOMA - STL

Nonstop1h 15mSouthwest

Fri 1/24:40 pmSTL - OMA

Nonstop1h 20mSouthwest

Deal found 12/16

$563

Sat 12/206:10 pmOMA - STL

1 stop3h 20mSouthwest

Wed 12/3110:25 amSTL - OMA

Nonstop1h 20mSouthwest

Deal found 12/16

$608

Best flights from Iowa to St. Louis
Discover carefully curated flight deals from Iowa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Tue 1/136:10 amDSM - STL

Nonstop1h 20mSouthwest

Wed 1/1410:15 amSTL - DSM

Nonstop1h 10mSouthwest

Deal found 12/17

$133

Fri 1/305:16 pmDSM - STL

1 stop6h 21mDelta

Fri 2/66:10 amSTL - DSM

1 stop4h 09mDelta

Deal found 12/16

$159

Mon 1/56:52 pmDSM - STL

1 stop4h 52mAmerican Airlines

Fri 1/95:04 pmSTL - DSM

1 stop6h 19mAmerican Airlines

Deal found 12/17

$159

Tue 1/138:00 amOMA - STL

1 stop6h 30mUnited Airlines

Tue 1/2011:20 amSTL - OMA

1 stop6h 16mUnited Airlines

Deal found 12/16

$191

Thu 1/81:11 pmOMA - STL

1 stop20h 51mMultiple Airlines

Sun 1/119:46 pmSTL - OMA

1 stop13h 55mMultiple Airlines

Deal found 12/17

$242

Sat 1/3110:59 amDSM - STL

1 stop3h 39mDelta

Sat 2/73:31 pmSTL - DSM

1 stop5h 53mDelta

Deal found 12/17

$159

Fri 1/3011:26 amDSM - STL

1 stop6h 24mDelta

Sun 2/16:10 amSTL - DSM

1 stop4h 09mDelta

Deal found 12/16

$159

Tue 1/65:22 amOMA - STL

1 stop5h 41mAmerican Airlines

Thu 1/810:17 amSTL - OMA

1 stop5h 57mAmerican Airlines

Deal found 12/15

$191

Fri 1/235:16 pmDSM - STL

1 stop6h 21mDelta

Sun 1/256:10 amSTL - DSM

1 stop4h 09mDelta

Deal found 12/17

$159

Thu 1/2210:59 amDSM - STL

2 stops9h 44mDelta

Mon 1/266:35 amSTL - DSM

2 stops9h 06mDelta

Deal found 12/16

$169

Mon 1/123:00 pmOMA - STL

1 stop7h 00mUnited Airlines

Thu 1/156:00 pmSTL - OMA

1 stop5h 07mUnited Airlines

Deal found 12/17

$251

Thu 1/83:00 pmOMA - STL

1 stop7h 00mUnited Airlines

Mon 1/124:35 pmSTL - OMA

1 stop5h 46mUnited Airlines

Deal found 12/17

$251

Tue 1/1310:59 amDSM - STL

2 stops9h 44mDelta

Wed 1/146:35 amSTL - DSM

2 stops9h 06mDelta

Deal found 12/17

$198

Tue 1/136:05 amOMA - STL

Nonstop1h 30mSouthwest

Tue 1/208:20 pmSTL - OMA

Nonstop1h 20mSouthwest

Deal found 12/16

$293

Sun 2/86:35 pmOMA - STL

1 stop4h 23mUnited Airlines

Sat 2/146:25 amSTL - OMA

1 stop4h 04mUnited Airlines

Deal found 12/17

$281

Thu 1/83:55 pmOMA - STL

Nonstop1h 15mSouthwest

Mon 1/128:20 pmSTL - OMA

Nonstop1h 20mSouthwest

Deal found 12/17

$313

Tue 1/66:05 amOMA - STL

Nonstop1h 30mSouthwest

Thu 1/810:15 amSTL - OMA

Nonstop1h 20mSouthwest

Deal found 12/15

$313

Sun 1/116:35 pmOMA - STL

1 stop4h 23mUnited Airlines

Tue 1/133:11 pmSTL - OMA

1 stop6h 47mUnited Airlines

Deal found 12/15

$292

Sat 2/76:00 amLSE - STL

1 stop4h 20mAmerican Airlines

Mon 2/162:24 pmSTL - LSE

1 stop3h 15mAmerican Airlines

Deal found 12/18

$490

Sat 2/216:00 amLSE - STL

1 stop8h 45mAmerican Airlines

Sat 2/286:33 pmSTL - LSE

1 stop29h 03mAmerican Airlines

Deal found 12/18

$507

Sat 1/246:00 amLSE - STL

1 stop4h 20mAmerican Airlines

Sat 1/3111:05 amSTL - LSE

1 stop5h 11mAmerican Airlines

Deal found 12/18

$536

Last-minute flights from Iowa to St. Louis
Discover last-minute flight deals from Iowa to St. Louis. Data last updated December 18, 2025 and is based on user searches.

Wed 12/315:55 pmDSM - STL

1 stop4h 21mDelta

Wed 1/75:25 pmSTL - DSM

1 stop3h 59mDelta

Deal found 12/16

$208

Wed 12/315:55 pmDSM - STL

1 stop4h 21mDelta

Thu 1/16:05 amSTL - DSM

1 stop5h 23mDelta

Deal found 12/17

$219

Tue 1/65:22 amOMA - STL

1 stop5h 41mAmerican Airlines

Thu 1/810:17 amSTL - OMA

1 stop5h 57mAmerican Airlines

Deal found 12/15

$191

Thu 1/81:11 pmOMA - STL

1 stop20h 51mMultiple Airlines

Sun 1/119:46 pmSTL - OMA

1 stop13h 55mMultiple Airlines

Deal found 12/17

$242

Thu 1/83:00 pmOMA - STL

1 stop7h 00mUnited Airlines

Mon 1/124:35 pmSTL - OMA

1 stop5h 46mUnited Airlines

Deal found 12/17

$251

Sun 1/116:35 pmOMA - STL

1 stop4h 23mUnited Airlines

Tue 1/133:11 pmSTL - OMA

1 stop6h 47mUnited Airlines

Deal found 12/15

$292

Tue 1/136:10 amDSM - STL

Nonstop1h 20mSouthwest

Wed 1/1410:15 amSTL - DSM

Nonstop1h 10mSouthwest

Deal found 12/17

$133

Tue 1/1310:59 amDSM - STL

2 stops9h 44mDelta

Wed 1/146:35 amSTL - DSM

1 stop4h 49mDelta

Deal found 12/17

$162

Tue 1/136:05 amOMA - STL

Nonstop1h 30mSouthwest

Tue 1/208:20 pmSTL - OMA

Nonstop1h 20mSouthwest

Deal found 12/16

$293

Thu 1/2210:21 amDSM - STL

1 stop6h 16mDelta

Mon 1/266:35 amSTL - DSM

2 stops9h 06mDelta

Deal found 12/16

$164

Fri 1/3011:26 amDSM - STL

1 stop6h 24mDelta

Fri 2/66:10 amSTL - DSM

1 stop4h 09mDelta

Deal found 12/16

$159

Sat 1/3112:14 pmOMA - STL

1 stop5h 59mAmerican Airlines

Sat 2/78:13 amSTL - OMA

1 stop6h 23mAmerican Airlines

Deal found 12/17

$306

One-way flights from Iowa to St. Louis
Search for one-way flight options from Iowa to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Fri 1/168:47 pmOMA - STL

1 stop18h 01mFrontier

Deal found 12/17

$66

Wed 1/213:20 pmDSM - STL

Nonstop1h 15mSouthwest

Deal found 12/17

$67

Wed 1/1412:04 pmDSM - STL

1 stop4h 33mDelta

Deal found 12/17

$79

Sat 1/1710:59 amDSM - STL

1 stop4h 01mDelta

Deal found 12/17

$80

Tue 1/63:07 pmOMA - STL

1 stop8h 05mAmerican Airlines

Deal found 12/16

$80

Sat 1/176:45 amDSM - STL

Nonstop1h 15mSouthwest

Deal found 12/17

$86

Thu 1/158:00 amOMA - STL

1 stop6h 30mUnited Airlines

Deal found 12/15

$96

Thu 1/158:19 pmOMA - STL

1 stop22h 13mFrontier

Deal found 12/17

$97

Thu 1/154:25 pmDSM - STL

1 stop6h 47mAmerican Airlines

Deal found 12/17

$110

Tue 1/135:04 pmOMA - STL

1 stop6h 08mAmerican Airlines

Deal found 12/17

$110

Mon 1/124:21 pmDSM - STL

2 stops7h 18mDelta

Deal found 12/17

$115

Thu 2/1211:32 amOMA - STL

1 stop25h 37mFrontier

Deal found 12/16

$117

Find flight deals from Iowa to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$133 (Southwest)
One-way from	$66 (Trip.com)
Popular in	July
Cheapest in	September
Average price	$407
Good round-trip deal	$105 or less
Good one-way deal	$203 or less

Provider with most accurate pricing for Des Moines-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Lambert-St Louis flights.

Search Deals

From Iowa to Lambert-St Louis

Search Deals

One-way flight from Iowa to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($35 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 8% potential price decrease ($25 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Iowa to Lambert-St Louis.

Search Deals

Price to beat on a one-way flight from Iowa to Lambert-St Louis.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 1/13

6:10 am-7:30 am

Nonstop1h 20m

Lambert-St Louis

Wed 1/14

10:15 am-11:25 am

Nonstop1h 10m

$133

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 1/30

5:16 pm-11:37 pm

1 stop6h 21m

Lambert-St Louis

Fri 2/6

6:10 am-10:19 am

1 stop4h 09m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 1/5

6:52 pm-11:44 pm

1 stop4h 52m

Lambert-St Louis

Fri 1/9

5:04 pm-11:23 pm

1 stop6h 19m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sat 1/31

10:59 am-2:38 pm

1 stop3h 39m

Lambert-St Louis

Sat 2/7

3:31 pm-9:24 pm

1 stop5h 53m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 1/30

11:26 am-5:50 pm

1 stop6h 24m

Lambert-St Louis

Sun 2/1

6:10 am-10:19 am

1 stop4h 09m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 1/23

5:16 pm-11:37 pm

1 stop6h 21m

Lambert-St Louis

Sun 1/25

6:10 am-10:19 am

1 stop4h 09m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 1/22

10:59 am-8:43 pm

2 stops9h 44m

Lambert-St Louis

Mon 1/26

6:35 am-3:41 pm

2 stops9h 06m

$169

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 1/13

8:00 am-2:30 pm

1 stop6h 30m

Lambert-St Louis

Tue 1/20

11:20 am-5:36 pm

1 stop6h 16m

$191

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 1/6

5:22 am-11:03 am

1 stop5h 41m

Lambert-St Louis

Thu 1/8

10:17 am-4:14 pm

1 stop5h 57m

$191

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 1/13

10:59 am-8:43 pm

2 stops9h 44m

Lambert-St Louis

Wed 1/14

6:35 am-3:41 pm

2 stops9h 06m

$198

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 40 results

Best time to book a flight from Iowa to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to St. Louis

What is the cheapest time of day to fly from IA to STL?

Unlike at noon, when flights are generally more expensive, you can save up to 26% on flights from Iowa to St. Louis by exploring options for tickets in the afternoon.

Related info for your journey

What airport do you fly into for flights to St. Louis from Iowa?
Lambert-St Louis (STL) is the airport you will fly into if you book a flight from Iowa to St. Louis. It is only a 12.7 mi journey from Lambert-St Louis (STL) to St. Louis’s city center.
How popular is this Iowa to St. Louis flight route?
Within the past month, 33 users have taken a look at flights from Iowa to Lambert-St Louis.
How long is the flight from Iowa to St. Louis?
A quick flight from Iowa to St. Louis can take about 1h 20m. Southwest provides one of the quickest options available for as low as $133. Airlines will cover a distance of 259 mi. This flight may include one or multiple stops.
What are the most popular routes from Iowa to St. Louis?
The most popular flight routes from Iowa to St. Louis are Des Moines - Lambert-St Louis, Omaha Eppley Airfield - Lambert-St Louis and La Crosse - Lambert-St Louis.
What are the cheapest flights from Iowa to St. Louis?
On average you can expect to pay $323 for a flight from Iowa to St. Louis. The cheapest flight overall is $130 while the most popular route, (Des Moines - Lambert-St Louis) is currently priced at $159.
Can I find deals for flights from Iowa to St. Louis that include hotel bookings?
Yes. In addition to deals on Iowa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to St. Louis.
Can I find deals for business class flights from Iowa to St. Louis?
Yes. Cheapflights offers flight deals from Iowa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Edwardsville

O'Fallon

Fairview Heights

Maryland Heights

Collinsville

Swansea

Eureka

Glencoe

St. Peters

Chesterfield

Alton

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Iowa to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Southern / Mokulele	Cheapest$61	Average$85	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$97	Average$254	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$66+ Cheap flights from Iowa to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Iowa to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Iowa to St. Louis

Cheapest flights from Iowa to St. LouisExplore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Iowa to St. Louis

Keep the following information in mind while searching for Iowa to St. Louis flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to St. Louis that are best for you.

Best time to book a flight from Iowa to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to St. Louis

What is the cheapest time of day to fly from IA to STL?

Find hourly flight availability from Iowa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Related info for your journey

Find useful and relevant information for your journey from Iowa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Iowa?

How popular is this Iowa to St. Louis flight route?

How long is the flight from Iowa to St. Louis?

What are the most popular routes from Iowa to St. Louis?

What are the cheapest flights from Iowa to St. Louis?

Can I find deals for flights from Iowa to St. Louis that include hotel bookings?

How can I find direct flights from Iowa to St. Louis?

Can I find deals for business class flights from Iowa to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Iowa to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Iowa to St. Louis
Explore the most affordable flight options available from Iowa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.