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Spartanburg

$113+ Cheap flights from Knoxville (TYS) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CLT
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Knoxville to Spartanburg

Keep the following information in mind while searching for Knoxville to Spartanburg flight deals. Data was last updated September 16, 2025.

Round-trip from

$176
(Kiwi.com)

One-way from

$113
(Kiwi.com)

Popular in

June

Cheapest in

April

Average price

$519
From Knoxville McGhee Tyson to Spartanburg
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One-way flight from Knoxville McGhee Tyson to Spartanburg
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Highest demand for flights based on searches. 11% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Spartanburg

Cheapest flights from Knoxville to Spartanburg
Explore the most affordable flight options available from Knoxville to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:42 pmTYS - CLT
1 stop13h 55mMultiple Airlines
Sun 11/165:06 pmCLT - TYS
1 stop25h 30mMultiple Airlines
Deal found 9/16$176
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1312:08 pmTYS - CLT
1 stop8h 51mMultiple Airlines
Mon 10/208:55 amCLT - TYS
1 stop14h 21mMultiple Airlines
Deal found 9/15$222
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:03 amTYS - CLT
1 stop24h 23mAmerican Airlines
Sun 10/198:20 amCLT - TYS
Nonstop1h 12mAmerican Airlines
Deal found 9/16$229
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1811:08 amTYS - CLT
1 stop12h 20mMultiple Airlines
Sun 10/1910:06 pmCLT - TYS
1 stop11h 50mMultiple Airlines
Deal found 9/16$231
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:26 pmTYS - CLT
1 stop18h 58mMultiple Airlines
Sun 11/210:06 pmCLT - TYS
1 stop14h 27mMultiple Airlines
Deal found 9/14$244
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:26 pmTYS - CLT
1 stop7h 02mMultiple Airlines
Wed 10/225:45 amCLT - TYS
1 stop9h 51mMultiple Airlines
Deal found 9/15$255
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/221:22 pmTYS - CLT
1 stop23h 31mMultiple Airlines
Mon 9/298:51 pmCLT - TYS
1 stop13h 44mMultiple Airlines
Deal found 9/15$258
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2510:43 amTYS - CLT
1 stop19h 43mAmerican Airlines
Sun 10/268:20 amCLT - TYS
Nonstop1h 12mAmerican Airlines
Deal found 9/13$269

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Knoxville to Spartanburg that are best for you.

Fly from

Knoxville

Fly to

Spartanburg

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 11/14

6:42 pm-8:37 am

1 stop13h 55m

Charlotte Douglas

Sun 11/16

5:06 pm-6:36 pm

1 stop25h 30m

$176

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 10/13

12:08 pm-11:28 pm

1 stop11h 20m

Charlotte Douglas

Mon 10/20

5:49 pm-10:33 am

1 stop16h 44m

$228

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sat 10/18

6:03 am-6:26 am

1 stop24h 23m

Charlotte Douglas

Sun 10/19

8:20 am-9:32 am

Nonstop1h 12m

$229

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sat 10/18

11:08 am-11:28 pm

1 stop12h 20m

Charlotte Douglas

Sun 10/19

10:06 pm-9:56 am

1 stop11h 50m

$231

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sat 10/25

10:43 am-6:26 am

1 stop19h 43m

Charlotte Douglas

Sun 10/26

8:20 am-9:32 am

Nonstop1h 12m

$269

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Wed 10/15

4:26 pm-11:28 pm

1 stop7h 02m

Charlotte Douglas

Wed 10/22

2:40 pm-9:07 pm

2 stops30h 27m

$273

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Wed 10/1

3:21 pm-12:53 pm

1 stop21h 32m

Charlotte Douglas

Sun 10/5

5:45 am-8:25 pm

1 stop14h 40m

$281

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 9/29

1:22 pm-12:53 pm

1 stop23h 31m

Charlotte Douglas

Fri 10/3

1:48 pm-11:36 pm

1 stop9h 48m

$292

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Thu 11/13

7:17 pm-5:17 pm

1 stop22h 00m

$113

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Wed 10/15

7:15 am-1:35 pm

1 stop6h 20m

$117

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 19 results
1
2

Best time to book a flight from Knoxville to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spartanburg

What is the cheapest month to book a flight from Knoxville to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $248). Flying from Knoxville to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SB1?

Find hourly flight availability from Knoxville to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Spartanburg as you normally would.

What is the cheapest day to fly from Knoxville to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Spartanburg flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Knoxville to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spartanburg?

    If you book a flight to Spartanburg from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 6 flights from McGhee Tyson to Spartanburg per day from 2 different airlines.

  • How long is the flight from Knoxville to Spartanburg?

    Airlines like American Airlines fly from Knoxville to Spartanburg in about 24h 23m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 176 mi.

  • What are the most reliable airlines from Knoxville to Spartanburg?

    Before booking your flight to Spartanburg from Knoxville, check out the most reliable airlines to get you to your destination on time: British Airways (93%), Piedmont Airlines (83%), American Airlines( 81%).

  • What are the cheapest flights from Knoxville to Spartanburg?

    The cheapest flight price from Knoxville to Spartanburg is $125. On average you can expect to pay $1,213. The most popular route, (Knoxville McGhee Tyson - Charlotte Douglas), can usually be booked for $220.

  • Can I find deals for flights from Knoxville to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spartanburg.

  • Can I find deals for business class flights from Knoxville to Spartanburg?

    Yes. Cheapflights offers flight deals from Knoxville to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $248). Flying from Knoxville to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 2 airlines flying from Knoxville to Spartanburg

Discover the top 2 airlines that operate flights from Knoxville to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$498FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$334FlexibilityNo cancel feeOn-timeN/A

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