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Spartanburg

$108+ Cheap flights from Knoxville (TYS) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CLT
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Find flight deals from Knoxville to Spartanburg

Cheapest flights from Knoxville to Spartanburg
Explore the most affordable flight options available from Knoxville to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/79:20 pmTYS - CLT
1 stop15h 03mMultiple Airlines
dom. 11/99:20 pmCLT - TYS
1 stop25h 54mMultiple Airlines
Deal found 10/28$205
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/124:32 pmTYS - CLT
1 stop16h 30mMultiple Airlines
dom. 11/169:20 pmCLT - TYS
1 stop16h 37mMultiple Airlines
Deal found 10/28$233
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/266:18 pmTYS - CLT
1 stop21h 14mMultiple Airlines
mié. 12/35:59 pmCLT - TYS
1 stop17h 54mMultiple Airlines
Deal found 10/29$234
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/109:27 pmTYS - CLT
1 stop16h 05mMultiple Airlines
jue. 11/132:45 pmCLT - TYS
1 stop8h 14mMultiple Airlines
Deal found 10/29$235
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/219:45 pmTYS - CLT
1 stop19h 05mMultiple Airlines
lun. 11/242:47 pmCLT - TYS
1 stop8h 05mMultiple Airlines
Deal found 10/28$236
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/219:35 pmTYS - CLT
1 stop10h 41mMultiple Airlines
dom. 11/237:08 pmCLT - TYS
1 stop15h 22mMultiple Airlines
Deal found 10/28$241
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/198:15 amTYS - CLT
1 stop11h 43mMultiple Airlines
vie. 11/2111:56 amCLT - TYS
1 stop9h 34mMultiple Airlines
Deal found 10/28$255
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/149:00 amTYS - CLT
1 stop11h 33mMultiple Airlines
lun. 11/176:44 pmCLT - TYS
1 stop15h 50mMultiple Airlines
Deal found 10/27$259
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/255:28 pmTYS - CLT
1 stop14h 48mMultiple Airlines
vie. 11/2811:56 amCLT - TYS
1 stop7h 23mMultiple Airlines
Deal found 10/28$263

Cheap flight deals from Knoxville to Spartanburg

Keep the following information in mind while searching for Knoxville to Spartanburg flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$234
(Kiwi.com)

One-way from

$108
(Kiwi.com)

Popular in

June

Cheapest in

April

Average price

$515
Provider with most accurate pricing for Knoxville McGhee Tyson-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Charlotte Douglas flights.
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From Knoxville McGhee Tyson to Spartanburg
Search Deals
One-way flight from Knoxville McGhee Tyson to Spartanburg
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Knoxville to Spartanburg that are best for you.

Fly from

Knoxville

Fly to

Spartanburg

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

mié. 11/26

6:18 pm-3:32 pm

1 stop21h 14m

Charlotte Douglas

mié. 12/3

5:59 pm-11:53 am

1 stop17h 54m

$234

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

lun. 11/10

9:27 pm-1:32 pm

1 stop16h 05m

Charlotte Douglas

jue. 11/13

2:45 pm-10:59 pm

1 stop8h 14m

$235

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

vie. 11/21

9:35 pm-8:16 am

1 stop10h 41m

Charlotte Douglas

dom. 11/23

7:08 pm-10:30 am

1 stop15h 22m

$241

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

mié. 11/19

8:15 am-7:58 pm

1 stop11h 43m

Charlotte Douglas

vie. 11/21

11:56 am-9:30 pm

1 stop9h 34m

$255

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

jue. 12/11

6:30 am-4:49 pm

1 stop10h 19m

Charlotte Douglas

mar. 12/16

2:58 pm-2:03 pm

1 stop23h 05m

$269

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

vie. 11/14

9:00 am-8:33 pm

1 stop11h 33m

Charlotte Douglas

lun. 11/17

2:58 pm-10:34 am

2 stops19h 36m

$284

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

vie. 11/14

3:41 pm-9:02 am

1 stop17h 21m

Charlotte Douglas

dom. 11/16

10:42 pm-6:36 pm

2 stops19h 54m

$285

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

vie. 11/21

9:45 pm-1:26 pm

2 stops15h 41m

Charlotte Douglas

lun. 11/24

2:47 pm-10:52 pm

1 stop8h 05m

$311

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

lun. 1/26

8:30 am-12:59 am

1 stop16h 29m

$108

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

mié. 12/31

11:08 am-8:33 pm

1 stop9h 25m

$118

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 17 results
1
2

Best time to book a flight from Knoxville to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spartanburg

What is the cheapest month to book a flight from Knoxville to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $265). Flying from Knoxville to Spartanburg in October is currently the most expensive (average of $391). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SB1?

Find hourly flight availability from Knoxville to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

When flying from Knoxville to Spartanburg, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 70% versus a flight at noon.

What is the cheapest day to fly from Knoxville to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Spartanburg flight should consider departing on Monday evenings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated octubre 30, 2025.
Read through reviews of airlines operating flights from Knoxville to Spartanburg, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,034 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,034 reviews
American Airlines
7.2
Good
11,034 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spartanburg?

    If you book a flight to Spartanburg from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 2 flights from McGhee Tyson to Spartanburg per day from 2 different airlines.

  • What are the most reliable airlines from Knoxville to Spartanburg?

    Before booking your flight to Spartanburg from Knoxville, check out the most reliable airlines to get you to your destination on time: Envoy Air (100%), Piedmont Airlines (90%), American Airlines( 88%).

  • What are the cheapest flights from Knoxville to Spartanburg?

    The cheapest flight price from Knoxville to Spartanburg is $160. On average you can expect to pay $873. The most popular route, (Knoxville McGhee Tyson - Charlotte Douglas), can usually be booked for $205.

  • Can I find deals for flights from Knoxville to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spartanburg.

  • Can I find deals for business class flights from Knoxville to Spartanburg?

    Yes. Cheapflights offers flight deals from Knoxville to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $265). Flying from Knoxville to Spartanburg in October is currently the most expensive (average of $391). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 2 airlines flying from Knoxville to Spartanburg

Discover the top 2 airlines that operate flights from Knoxville to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$505FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$334FlexibilityNo cancel feeOn-timeN/A

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