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South Carolina

$78+ Cheap flights from Colorado to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Colorado to South Carolina

Cheapest flights from Colorado to South Carolina
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:05 amDEN - CLT
Nonstop3h 17mFrontier
Wed 12/245:14 pmCLT - DEN
Nonstop4h 01mFrontier
Deal found 10/29$166
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:59 pmDEN - CLT
1 stop11h 28mFrontier
Wed 12/245:14 pmCLT - DEN
Nonstop4h 01mFrontier
Deal found 10/29$167
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:00 amDEN - CLT
1 stop10h 59mMultiple Airlines
Sun 11/238:52 pmCLT - DEN
1 stop14h 11mMultiple Airlines
Deal found 10/29$169
This Cheapflightsfares deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:05 pmDEN - CLT
Nonstop3h 17mFrontier
Sun 11/166:02 pmCLT - DEN
Nonstop3h 54mFrontier
Deal found 10/30$170
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:05 amDEN - CLT
Nonstop3h 17mFrontier
Thu 12/2512:17 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 10/29$171
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:05 amDEN - CLT
Nonstop3h 17mFrontier
Thu 12/2512:17 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 10/29$172
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:08 pmDEN - CLT
1 stop13h 34mFrontier
Thu 11/66:07 pmCLT - DEN
Nonstop3h 54mFrontier
Deal found 10/28$173
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:00 pmDEN - CLT
Nonstop3h 17mFrontier
Sun 11/166:02 pmCLT - DEN
Nonstop3h 54mFrontier
Deal found 10/27$174
This Cheapflightsfares deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:05 amDEN - CLT
Nonstop3h 17mFrontier
Thu 1/112:17 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 10/30$176
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:07 amDEN - CLT
Nonstop3h 16mFrontier
Fri 12/125:44 pmCLT - DEN
Nonstop4h 01mFrontier
Deal found 10/28$177
This Cheapflightsfares deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/612:00 pmDEN - CLT
Nonstop3h 17mFrontier
Tue 11/119:05 pmCLT - DEN
1 stop28h 11mFrontier
Deal found 10/28$178
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:43 pmDEN - CLT
Nonstop3h 13mUnited Airlines
Tue 12/98:15 amCLT - DEN
Nonstop3h 50mUnited Airlines
Deal found 10/28$179

Cheap flight deals from Colorado to South Carolina

Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$166
(Priceline)

One-way from

$78
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$414

Good round-trip deal

$329 or less

Good one-way deal

$188 or less
Provider with most accurate pricing for Denver Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Myrtle Beach Intl flights.
Search Deals
From Colorado to South Carolina
Search Deals
One-way flight from Colorado to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Colorado to South Carolina.
Search Deals
Price to beat on a one-way flight from Colorado to South Carolina.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.

Fly from

Colorado

Fly to

South Carolina

Route

Depart

Return

Price

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 12/5

5:43 pm-10:56 pm

Nonstop3h 13m

Charlotte Douglas

Mon 12/8

4:20 pm-6:22 pm

Nonstop4h 02m

$197

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 12/12

5:43 pm-10:56 pm

Nonstop3h 13m

Charlotte Douglas

Mon 12/15

8:15 am-10:05 am

Nonstop3h 50m

$197

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 1/9

7:00 am-4:20 pm

1 stop7h 20m

Charlotte Douglas

Sun 1/11

5:50 am-12:10 pm

2 stops8h 20m

$204

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 1/15

6:05 am-4:07 pm

1 stop8h 02m

Charlotte Douglas

Sun 1/18

11:35 am-5:26 pm

1 stop7h 51m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Mon 12/1

12:50 am-8:48 am

1 stop5h 58m

Charlotte Douglas

Mon 12/8

9:51 am-3:10 pm

1 stop7h 19m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 1/8

1:15 pm-8:40 pm

1 stop5h 25m

Charlotte Douglas

Sun 1/11

6:00 am-10:33 am

1 stop6h 33m

$217

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sat 11/15

10:00 am-3:14 pm

Nonstop3h 14m

Charlotte Douglas

Mon 11/17

4:17 pm-6:16 pm

Nonstop3h 59m

$233

DenverMyrtle Beach

DEN - MYR

DENMYR

Denver Intl

Sat 1/10

6:40 pm-10:41 am

2 stops38h 01m

Myrtle Beach Intl

Fri 1/23

6:09 pm-4:51 pm

1 stop24h 42m

$251

DenverCharleston

DEN - CHS

DENCHS

Denver Intl

Sat 1/24

4:50 pm-8:33 am

1 stop13h 43m

Charleston

Wed 1/28

7:00 am-8:15 am

2 stops27h 15m

$252

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 12/4

8:05 am-4:20 pm

2 stops6h 15m

Charlotte Douglas

Sun 12/7

5:50 am-10:45 am

2 stops6h 55m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 60 results
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Best time to book a flight from Colorado to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to South Carolina

What is the cheapest month to book a flight from Colorado to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $140). Flying from Colorado to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to SC?

Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from Colorado to South Carolina in the evening. By choosing this option you can save up to 26% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Colorado to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Colorado to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Colorado to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Colorado to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,122 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to South Carolina flight route?

    Within the past month, 2 users have taken a look at flights from Colorado to South Carolina.

  • How long is the flight from Colorado to South Carolina?

    United Airlines, Southwest, and Delta can get you from Colorado to South Carolina in just under 3h 13m. Your travel time can differ by up to 4h 49m. Airlines will cover a distance of 1334 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to South Carolina one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $90. However, be on the lookout for offers from JetBlue and Southwest, as they are both options that can get you from Colorado to South Carolina for a low price.

  • Can I find deals for flights from Colorado to South Carolina that include hotel bookings?

    Yes. In addition to deals on Colorado to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to South Carolina.

  • Can I find deals for business class flights from Colorado to South Carolina?

    Yes. Cheapflights offers flight deals from Colorado to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $140). Flying from Colorado to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Colorado to South Carolina

Discover the top 5 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$136Average$276FlexibilityNo cancel feeOn-time62%
DeltaCheapest$154Average$371FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$171Average$475FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$246Average$495FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$268Average$500FlexibilityNo cancel feeOn-time63%

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