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South Carolina

$84+ Cheap flights from Colorado to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Colorado to South Carolina

Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$149
(Cheapflightsfares)

One-way from

$84
(Southwest)

Popular in

December

Cheapest in

August

Average price

$345

Good round-trip deal

$362 or less

Good one-way deal

$175 or less
From Colorado to South Carolina
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One-way flight from Colorado to South Carolina
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Highest demand for flights based on searches. 10% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Colorado to South Carolina.
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Price to beat on a one-way flight from Colorado to South Carolina.
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Find flight deals from Colorado to South Carolina

Cheapest flights from Colorado to South Carolina
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:04 amDEN - CLT
1 stop10h 57mFrontier
Mon 10/68:50 amCLT - DEN
1 stop24h 46mFrontier
Deal found 9/15$150
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:04 amDEN - CLT
1 stop10h 57mFrontier
Sun 10/58:55 amCLT - DEN
1 stop25h 00mFrontier
Deal found 9/15$151
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/118:22 pmDEN - CLT
1 stop10h 46mFrontier
Mon 10/1310:05 pmCLT - DEN
1 stop21h 04mFrontier
Deal found 9/14$152
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1612:34 amDEN - CLT
1 stop15h 55mFrontier
Mon 10/2010:03 amCLT - DEN
1 stop25h 01mFrontier
Deal found 9/13$153
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:50 pmDEN - CLT
1 stop15h 10mFrontier
Sat 10/114:00 pmCLT - DEN
1 stop18h 15mFrontier
Deal found 9/13$154
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:36 amDEN - CLT
1 stop8h 27mFrontier
Mon 10/205:34 pmCLT - DEN
Nonstop3h 52mFrontier
Deal found 9/14$155
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:36 amDEN - CLT
1 stop8h 27mFrontier
Thu 10/235:34 pmCLT - DEN
Nonstop3h 52mFrontier
Deal found 9/13$156
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2611:20 amDEN - CLT
Nonstop3h 19mFrontier
Tue 11/42:27 pmCLT - DEN
1 stop10h 49mFrontier
Deal found 9/15$157
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:18 amDEN - CLT
Nonstop3h 25mFrontier
Sat 10/42:01 pmCLT - DEN
1 stop11h 12mFrontier
Deal found 9/14$158
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2111:59 pmDEN - CLT
1 stop17h 06mFrontier
Sat 9/272:01 pmCLT - DEN
1 stop11h 12mFrontier
Deal found 9/13$159
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:34 amDEN - CLT
1 stop15h 55mFrontier
Tue 10/282:27 pmCLT - DEN
1 stop10h 49mFrontier
Deal found 9/14$160
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:55 pmDEN - CLT
1 stop11h 16mFrontier
Mon 9/292:01 pmCLT - DEN
1 stop11h 12mFrontier
Deal found 9/14$161

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.

Fly from

Colorado

Fly to

South Carolina

Route

Depart

Return

Price

DenverMyrtle Beach

DEN - MYR

DENMYR

Denver Intl

Fri 10/24

11:40 pm-9:40 am

1 stop8h 00m

Myrtle Beach Intl

Tue 10/28

8:05 am-12:40 pm

1 stop6h 35m

$179

DenverMyrtle Beach

DEN - MYR

DENMYR

Denver Intl

Fri 10/24

11:40 pm-9:40 am

1 stop8h 00m

Myrtle Beach Intl

Wed 10/29

4:10 pm-10:40 pm

1 stop8h 30m

$183

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 11/13

5:40 pm-10:53 pm

Nonstop3h 13m

Charlotte Douglas

Tue 11/18

8:15 am-10:05 am

Nonstop3h 50m

$188

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 10/7

11:40 pm-9:55 am

1 stop8h 15m

Charlotte Douglas

Sun 10/12

5:25 am-7:05 am

Nonstop3h 40m

$218

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Tue 10/7

12:15 pm-9:30 pm

2 stops7h 15m

Charlotte Douglas

Tue 10/14

6:10 pm-10:20 pm

1 stop6h 10m

$224

DenverColumbia

DEN - CAE

DENCAE

Denver Intl

Wed 11/12

12:16 am-3:40 pm

1 stop13h 24m

Columbia Metropolitan

Sun 11/16

3:05 pm-12:02 pm

2 stops22h 57m

$233

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sat 10/4

3:35 pm-8:45 pm

Nonstop3h 10m

Charlotte Douglas

Sat 10/11

9:00 am-1:55 pm

1 stop6h 55m

$234

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 11/7

4:47 pm-11:55 pm

1 stop5h 08m

Greenville

Mon 11/10

7:59 pm-12:13 am

1 stop6h 14m

$237

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Mon 10/13

12:50 am-8:59 am

1 stop6h 09m

Greenville

Tue 10/21

7:52 am-1:52 pm

1 stop8h 00m

$237

DenverMyrtle Beach

DEN - MYR

DENMYR

Denver Intl

Wed 10/22

4:47 pm-11:59 pm

1 stop5h 12m

Myrtle Beach Intl

Sat 10/25

4:00 pm-8:15 pm

1 stop6h 15m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
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6

Best time to book a flight from Colorado to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to South Carolina

What is the cheapest month to book a flight from Colorado to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to SC?

Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to South Carolina as you normally would.

Weekly flight availability from Colorado to South Carolina

Explore weekly flight availability from Colorado to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from USCO to USSC are scheduled on a Monday (2 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 15, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,172 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to South Carolina flight route?

    Within the past month, 2 users have taken a look at flights from Colorado to South Carolina.

  • How long is the flight from Colorado to South Carolina?

    Southwest, United Airlines, and Delta can get you from Colorado to South Carolina in just under 3h 13m. Your travel time can differ by up to 4h 47m. Airlines will cover a distance of 1334 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to South Carolina one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $84. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Colorado to South Carolina for a low price.

  • Can I find deals for flights from Colorado to South Carolina that include hotel bookings?

    Yes. In addition to deals on Colorado to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to South Carolina.

  • Can I find deals for business class flights from Colorado to South Carolina?

    Yes. Cheapflights offers flight deals from Colorado to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Colorado to South Carolina

Discover the top 5 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$136Average$275FlexibilityNo cancel feeOn-time62%
DeltaCheapest$154Average$367FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$188Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$204Average$492FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$268Average$496FlexibilityNo cancel feeOn-time63%

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