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South Carolina

$89+ Cheap flights from Colorado to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Colorado to South Carolina

Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated July 31, 2025.

Round-trip from

$177
(American Airlines)

One-way from

$89
(American Airlines)

Popular in

December

Cheapest in

May

Average price

$416

Good round-trip deal

$346 or less

Good one-way deal

$246 or less
From Colorado to South Carolina
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One-way flight from Colorado to South Carolina
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Highest demand for flights based on searches. 7% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Colorado to South Carolina.
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Price to beat on a one-way flight from Colorado to South Carolina.
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Find flight deals from Colorado to South Carolina

Cheapest flights from Colorado to South Carolina
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2711:59 pmDEN - CLT
Nonstop3h 06mAmerican Airlines
Tue 10/710:51 amCLT - DEN
Nonstop3h 43mAmerican Airlines
Deal found 7/30$177
This Frontier deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2811:13 amDEN - CLT
Nonstop3h 24mFrontier
Sun 8/315:32 pmCLT - DEN
Nonstop3h 54mFrontier
Deal found 7/30$184
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/43:35 pmDEN - CLT
Nonstop3h 10mSouthwest
Tue 10/74:20 pmCLT - DEN
1 stop8h 20mSouthwest
Deal found 7/31$223
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:59 amDEN - CLT
1 stop7h 44mDelta
Mon 10/67:15 pmCLT - DEN
1 stop5h 49mDelta
Deal found 7/31$237
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/279:53 amDEN - GSP
Nonstop3h 05mUnited Airlines
Wed 9/34:30 pmGSP - DEN
Nonstop3h 27mUnited Airlines
Deal found 7/30$249
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2210:08 amDEN - SAV
Nonstop3h 16mUnited Airlines
Thu 8/284:45 pmSAV - DEN
1 stop8h 18mUnited Airlines
Deal found 7/31$259
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2410:39 amDEN - CHS
1 stop6h 18mDelta
Sat 9/272:55 pmCHS - DEN
1 stop7h 13mDelta
Deal found 7/29$265
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amCOS - CHS
1 stop5h 45mDelta
Sat 9/272:55 pmCHS - COS
1 stop7h 44mDelta
Deal found 7/30$265
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:00 amCOS - CAE
1 stop6h 23mDelta
Sat 8/235:15 pmCAE - COS
1 stop5h 26mDelta
Deal found 7/29$269
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:00 amDEN - CHS
1 stop6h 50mAmerican Airlines
Sat 8/301:05 pmCHS - DEN
2 stops8h 43mAmerican Airlines
Deal found 7/31$269
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/266:00 amDEN - GSP
1 stop5h 20mDelta
Thu 9/43:20 pmGSP - DEN
1 stop7h 18mDelta
Deal found 7/30$269
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:10 amDEN - CAE
1 stop6h 38mAmerican Airlines
Tue 9/27:34 pmCAE - DEN
1 stop5h 21mAmerican Airlines
Deal found 7/30$269

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.

Fly from

Colorado

Fly to

South Carolina

Route

Depart

Return

Price

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sat 9/27

11:59 pm-5:05 am

Nonstop3h 06m

Charlotte Douglas

Tue 10/7

10:51 am-12:34 pm

Nonstop3h 43m

$177

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Thu 8/28

11:13 am-4:37 pm

Nonstop3h 24m

Charlotte Douglas

Sun 8/31

5:32 pm-7:26 pm

Nonstop3h 54m

$184

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Wed 10/29

11:55 am-8:50 pm

1 stop6h 55m

Charlotte Douglas

Sat 11/1

2:00 pm-3:40 pm

Nonstop3h 40m

$223

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 9/26

6:00 am-1:02 pm

1 stop5h 02m

Charlotte Douglas

Sun 9/28

6:05 am-9:34 am

1 stop5h 29m

$237

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 8/27

9:53 am-2:58 pm

Nonstop3h 05m

Greenville

Wed 9/3

4:30 pm-5:57 pm

Nonstop3h 27m

$249

DenverSavannah

DEN - SAV

DENSAV

Denver Intl

Fri 8/22

10:08 am-3:24 pm

Nonstop3h 16m

Savannah/Hilton Head

Thu 8/28

4:45 pm-11:03 pm

1 stop8h 18m

$259

DenverCharleston

DEN - CHS

DENCHS

Denver Intl

Wed 9/24

10:39 am-6:57 pm

1 stop6h 18m

Charleston

Sat 9/27

2:55 pm-8:08 pm

1 stop7h 13m

$265

Colorado SpringsCharleston

COS - CHS

COSCHS

Colorado Springs

Tue 9/23

6:00 am-1:45 pm

1 stop5h 45m

Charleston

Sat 9/27

2:55 pm-8:39 pm

1 stop7h 44m

$265

DenverCharleston

DEN - CHS

DENCHS

Denver Intl

Sat 8/23

5:00 am-1:50 pm

1 stop6h 50m

Charleston

Sat 8/30

1:05 pm-7:48 pm

2 stops8h 43m

$269

DenverColumbia

DEN - CAE

DENCAE

Denver Intl

Wed 8/27

6:10 am-2:48 pm

1 stop6h 38m

Columbia Metropolitan

Tue 9/2

7:34 pm-10:55 pm

1 stop5h 21m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 60 results
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Best time to book a flight from Colorado to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to South Carolina

What is the cheapest month to book a flight from Colorado to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to SC?

Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 31, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Entertainment

7.1

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Entertainment

7.1

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Entertainment

7.1

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Entertainment

7.1

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Entertainment

7.1

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Entertainment

7.1

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to South Carolina flight route?

    Within the past month, 2 users have taken a look at flights from Colorado to South Carolina.

  • What are the cheapest airlines to fly from Colorado to South Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from Frontier and Allegiant Air, as they are both options that can get you from Colorado to South Carolina for a low price.

  • Can I find deals for flights from Colorado to South Carolina that include hotel bookings?

    Yes. In addition to deals on Colorado to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to South Carolina.

  • Can I find deals for business class flights from Colorado to South Carolina?

    Yes. Cheapflights offers flight deals from Colorado to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $217). Flying from Colorado to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Colorado to South Carolina

Discover the top 5 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$136Average$276FlexibilityNo cancel feeOn-time62%
DeltaCheapest$169Average$376FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$188Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$208Average$496FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$268Average$506FlexibilityNo cancel feeOn-time63%

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