$90+ Cheap flights from Colorado to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Jan 17 — Jan 241
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to South Carolina
Cheapest flights from Colorado to South CarolinaExplore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
This Frontier deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:05 amDEN - CLT
Nonstop3h 17mFrontier
Sun 1/47:09 pmCLT - DEN
1 stop7h 05mFrontier
Deal found 12/15![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:05 amDEN - CLT
Nonstop3h 17mFrontier
Fri 1/23:07 pmCLT - DEN
1 stop19h 20mFrontier
Deal found 12/15![Frontier logo]()
$168
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:05 amDEN - CLT
Nonstop3h 17mFrontier
Wed 12/315:14 pmCLT - DEN
Nonstop4h 01mFrontier
Deal found 12/17![Frontier logo]()
$172
This CheapOair deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:05 amDEN - CLT
Nonstop3h 17mFrontier
Thu 1/112:17 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 12/17![Frontier logo]()
$173
This Frontier deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:45 pmDEN - CLT
1 stop9h 47mFrontier
Thu 1/112:17 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 12/15![Frontier logo]()
$176
This Frontier deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:05 amDEN - CLT
Nonstop3h 17mFrontier
Tue 12/305:37 pmCLT - DEN
1 stop8h 30mFrontier
Deal found 12/15![Frontier logo]()
$181
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 pmDEN - CLT
1 stop9h 47mFrontier
Sun 1/47:09 pmCLT - DEN
1 stop7h 05mFrontier
Deal found 12/16![Frontier logo]()
$184
This Super.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:45 pmDEN - CLT
1 stop9h 27mFrontier
Thu 12/2512:17 pmCLT - DEN
Nonstop3h 58mFrontier
Deal found 12/15![Frontier logo]()
$201
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:15 amDEN - CLT
1 stop5h 25mSouthwest
Thu 1/15:10 pmCLT - DEN
1 stop7h 30mSouthwest
Deal found 12/16![Southwest logo]()
$208
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:38 pmCOS - CLT
1 stop5h 00mUnited Airlines
Wed 12/312:54 pmCLT - COS
2 stops9h 12mUnited Airlines
Deal found 12/16![United Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:28 pmGUC - CLT
1 stop5h 10mUnited Airlines
Tue 1/208:00 amCLT - GUC
1 stop8h 43mUnited Airlines
Deal found 12/15![United Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:59 pmDEN - GSP
1 stop6h 37mAmerican Airlines
Sat 1/37:00 amGSP - DEN
1 stop5h 36mAmerican Airlines
Deal found 12/15![American Airlines logo]()
$329
Find flight deals from Colorado to South Carolina
Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated December 18, 2025.
Most accurate provider | Mytrip 3 stars |
|---|---|
Most trusted provider | Mytrip 3 stars |
Round-trip from | $139 (Frontier) |
One-way from | $90 (American Airlines) |
Popular in | March |
Cheapest in | August |
Average price | $487 |
Good round-trip deal | $326 or less |
Good one-way deal | $168 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.
Fly from
Colorado
Fly to
South Carolina
Route
Depart
Return
Price
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Sat 1/10
11:59 pm-9:32 am
1 stop7h 33m
Charlotte Douglas
Mon 1/12
6:50 pm-8:55 pm
Nonstop4h 05m
$161
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Tue 1/13
6:27 pm-4:54 pm
3 stops20h 27m
Charlotte Douglas
Sun 1/18
6:43 pm-8:47 pm
Nonstop4h 04m
$167
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Tue 1/13
5:46 pm-10:59 pm
Nonstop3h 13m
Charlotte Douglas
Sun 1/18
8:00 am-10:00 am
Nonstop4h 00m
$199
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Fri 1/9
12:45 pm-5:55 pm
Nonstop3h 10m
Charlotte Douglas
Sun 1/11
3:45 pm-11:58 pm
1 stop10h 13m
$200
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Sat 1/10
11:59 pm-9:32 am
1 stop7h 33m
Charlotte Douglas
Mon 1/12
7:43 pm-1:02 pm
2 stops19h 19m
$207
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Wed 2/11
6:00 am-4:02 pm
1 stop8h 02m
Charlotte Douglas
Tue 2/17
9:54 am-3:38 pm
1 stop7h 44m
$217
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Thu 1/29
5:46 pm-10:59 pm
Nonstop3h 13m
Charlotte Douglas
Sun 2/1
8:00 am-10:00 am
Nonstop4h 00m
$217
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Tue 2/10
2:42 pm-11:54 pm
1 stop7h 12m
Charlotte Douglas
Tue 2/17
1:11 pm-5:24 pm
1 stop6h 13m
$217
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Sat 1/10
5:46 pm-10:59 pm
Nonstop3h 13m
Charlotte Douglas
Sat 1/17
6:10 am-12:38 pm
1 stop8h 28m
$218
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Sat 1/10
5:46 pm-10:59 pm
Nonstop3h 13m
Charlotte Douglas
Tue 1/13
8:00 am-10:00 am
Nonstop4h 00m
$219
Showing 1-10 of 60 results
Best time to book a flight from Colorado to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to South Carolina
What is the cheapest month to book a flight from Colorado to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $140). Flying from Colorado to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to SC?
Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.
It’s optimal to fly from Colorado to South Carolina in the evening. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Colorado to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Colorado to South Carolina. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their Colorado to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 18, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Colorado to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Colorado to South Carolina
Discover the top 5 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$130 | Average$276 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$154 | Average$370 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$171 | Average$461 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$231 | Average$483 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$259 | Average$502 | FlexibilityNo cancel fee | On-time69% |