$104+ Cheap flights from Colorado to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Apr 16 — Apr 231
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to South Carolina with Cheapflights
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Cheapest flights from Colorado to South CarolinaExplore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Thu 5/75:20 pm
CLT
- DEN
Nonstop4h 06m
Frontier
Deal found 3/16![Frontier logo]()
$127
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:34 am
DEN
- CLT
Nonstop3h 22m
Frontier
Mon 4/206:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/16![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Tue 4/217:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/16![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Thu 4/236:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/12![Frontier logo]()
$136
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Mon 4/276:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/15![Frontier logo]()
$137
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Sat 4/185:51 pm
CLT
- DEN
Nonstop4h 04m
Frontier
Deal found 3/16![Frontier logo]()
$138
This Cheapflightsfares deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:30 am
DEN
- CLT
Nonstop3h 22m
Frontier
Tue 5/197:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/12![Frontier logo]()
$141
This Cheapflightsfares deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
DEN
- CLT
1 stop7h 36m
Frontier
Sun 5/107:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/12![Frontier logo]()
$143
This eDestinos deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:25 pm
DEN
- CLT
1 stop20h 56m
Frontier
Sat 4/185:51 pm
CLT
- DEN
Nonstop4h 04m
Frontier
Deal found 3/16![Frontier logo]()
$144
This Super.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Thu 4/236:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/11![Frontier logo]()
$146
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Fri 4/246:30 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/12![Frontier logo]()
$147
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:54 pm
DEN
- MYR
1 stop18h 50m
Frontier
Sat 5/24:01 pm
MYR
- DEN
1 stop9h 08m
Frontier
Deal found 3/12![Frontier logo]()
$210
Best flights from Colorado to South CarolinaDiscover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
Discover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:35 am
DEN
- CLT
1 stop7h 35m
Southwest
Sat 4/1812:15 pm
CLT
- DEN
2 stops8h 55m
Southwest
Deal found 3/16![Southwest logo]()
$242
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:35 am
DEN
- CLT
1 stop6h 34m
Delta
Fri 4/244:54 pm
CLT
- DEN
1 stop7h 12m
Delta
Deal found 3/12![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:59 pm
DEN
- CHS
1 stop8h 24m
United Airlines
Sat 4/188:00 am
CHS
- DEN
Nonstop4h 05m
United Airlines
Deal found 3/12![United Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:39 pm
COS
- CLT
1 stop5h 25m
American Airlines
Wed 5/67:24 pm
CLT
- COS
1 stop6h 08m
American Airlines
Deal found 3/11![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:15 am
DEN
- MYR
2 stops8h 30m
Southwest
Sat 5/27:10 am
MYR
- DEN
2 stops9h 25m
Southwest
Deal found 3/12![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:40 pm
COS
- SAV
1 stop5h 11m
Delta
Tue 8/47:00 am
SAV
- COS
1 stop7h 59m
Delta
Deal found 3/11![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:15 am
DEN
- CLT
2 stops9h 00m
Southwest
Mon 4/206:15 am
CLT
- DEN
2 stops9h 15m
Southwest
Deal found 3/11![Southwest logo]()
$283
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:52 pm
DEN
- CHS
1 stop6h 07m
United Airlines
Tue 5/128:00 am
CHS
- DEN
Nonstop4h 05m
United Airlines
Deal found 3/12![United Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
COS
- MYR
1 stop6h 48m
Delta
Wed 4/223:49 pm
MYR
- COS
1 stop6h 31m
Delta
Deal found 3/13![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1011:59 pm
DEN
- CAE
1 stop8h 15m
United Airlines
Fri 4/177:38 pm
CAE
- DEN
1 stop7h 06m
United Airlines
Deal found 3/12![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:50 am
DEN
- CHS
2 stops7h 35m
Southwest
Tue 5/57:15 am
CHS
- DEN
2 stops11h 10m
Southwest
Deal found 3/12![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:40 pm
COS
- SAV
1 stop6h 58m
Delta
Fri 8/73:50 pm
SAV
- COS
1 stop7h 32m
Delta
Deal found 3/11![Delta logo]()
$322
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:50 pm
DEN
- MYR
1 stop8h 00m
Southwest
Wed 6/107:15 pm
MYR
- DEN
1 stop6h 25m
Southwest
Deal found 3/12![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:41 am
COS
- SAV
1 stop7h 40m
American Airlines
Sat 4/255:00 am
SAV
- COS
2 stops9h 49m
American Airlines
Deal found 3/14![American Airlines logo]()
$418
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
COS
- MYR
1 stop6h 17m
United Airlines
Wed 4/153:15 pm
MYR
- COS
1 stop8h 39m
United Airlines
Deal found 3/11![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:59 am
DEN
- CHS
1 stop6h 43m
Delta
Fri 7/107:59 pm
CHS
- DEN
1 stop5h 46m
Delta
Deal found 3/12![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:35 am
DEN
- SAV
1 stop7h 15m
Southwest
Thu 5/148:20 pm
SAV
- DEN
1 stop5h 25m
Southwest
Deal found 3/11![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
DEN
- HHH
1 stop6h 11m
United Airlines
Fri 5/83:08 pm
HHH
- DEN
1 stop8h 00m
United Airlines
Deal found 3/12![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:30 am
COS
- MYR
2 stops12h 00m
Southwest
Fri 5/83:45 pm
MYR
- COS
2 stops8h 30m
Southwest
Deal found 3/15![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/54:30 pm
DEN
- SAV
1 stop5h 29m
Delta
Fri 5/87:59 pm
SAV
- DEN
1 stop6h 34m
Delta
Deal found 3/12![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:00 am
COS
- MYR
1 stop5h 42m
American Airlines
Sat 9/54:26 pm
MYR
- COS
1 stop8h 31m
American Airlines
Deal found 3/15![American Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:45 am
DEN
- SAV
Nonstop3h 19m
United Airlines
Wed 4/154:19 pm
SAV
- DEN
Nonstop3h 59m
United Airlines
Deal found 3/11![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:35 am
DEN
- CHS
2 stops7h 55m
Southwest
Tue 5/127:40 am
CHS
- DEN
2 stops8h 40m
Southwest
Deal found 3/12![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:40 pm
COS
- SAV
1 stop6h 58m
Delta
Wed 8/511:00 am
SAV
- COS
2 stops12h 22m
Delta
Deal found 3/11![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
DEN
- MYR
1 stop6h 17m
United Airlines
Tue 4/2111:00 am
MYR
- DEN
1 stop7h 29m
United Airlines
Deal found 3/11![United Airlines logo]()
$371
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:25 pm
DEN
- CLT
2 stops8h 15m
Southwest
Tue 4/211:45 pm
CLT
- DEN
2 stops10h 55m
Southwest
Deal found 3/14![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:38 am
DEN
- HHH
1 stop5h 35m
American Airlines
Fri 6/52:43 pm
HHH
- DEN
1 stop7h 30m
American Airlines
Deal found 3/15![American Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:59 pm
DEN
- CAE
1 stop7h 57m
United Airlines
Wed 7/82:51 pm
CAE
- DEN
1 stop6h 54m
United Airlines
Deal found 3/14![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:47 am
DEN
- CAE
1 stop8h 00m
Delta
Mon 5/47:12 pm
CAE
- DEN
1 stop7h 24m
Delta
Deal found 3/16![Delta logo]()
$375
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:55 pm
DEN
- MYR
1 stop8h 10m
Southwest
Tue 6/24:05 pm
MYR
- DEN
2 stops8h 30m
Southwest
Deal found 3/11![Southwest logo]()
$314
Last-minute flights from Colorado to South CarolinaDiscover last-minute flight deals from Colorado to South Carolina. Data last updated March 17, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to South Carolina. Data last updated March 17, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Sat 4/185:51 pm
CLT
- DEN
Nonstop4h 04m
Frontier
Deal found 3/16![Frontier logo]()
$138
This eDestinos deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:25 pm
DEN
- CLT
1 stop20h 56m
Frontier
Sat 4/185:51 pm
CLT
- DEN
Nonstop4h 04m
Frontier
Deal found 3/16![Frontier logo]()
$144
This Super.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Thu 4/236:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/11![Frontier logo]()
$146
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Fri 4/246:30 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/12![Frontier logo]()
$147
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:34 am
DEN
- CLT
Nonstop3h 22m
Frontier
Mon 4/206:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/16![Frontier logo]()
$128
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1912:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Mon 4/206:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/12![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Tue 4/217:49 pm
CLT
- DEN
Nonstop4h 00m
Frontier
Deal found 3/16![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Thu 4/236:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/12![Frontier logo]()
$136
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Mon 4/276:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/15![Frontier logo]()
$137
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:54 pm
DEN
- MYR
1 stop18h 50m
Frontier
Sat 5/24:01 pm
MYR
- DEN
1 stop9h 08m
Frontier
Deal found 3/12![Frontier logo]()
$210
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:02 pm
DEN
- CLT
Nonstop3h 21m
Frontier
Mon 5/46:18 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 3/12![Frontier logo]()
$149
This Cheapflightsfares deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Thu 5/75:20 pm
CLT
- DEN
Nonstop4h 06m
Frontier
Deal found 3/16![Frontier logo]()
$127
One-way flights from Colorado to South CarolinaSearch for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
Search for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
This Super.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
DEN
- CLT
1 stop6h 44m
Frontier
Deal found 3/16![Frontier logo]()
$104
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:20 am
DEN
- MYR
1 stop8h 24m
Frontier
Deal found 3/16![Frontier logo]()
$105
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:59 pm
DEN
- CLT
1 stop8h 04m
Frontier
Deal found 3/12![Frontier logo]()
$105
This Trip.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:00 pm
DEN
- CHS
1 stop14h 06m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:00 pm
DEN
- CLT
2 stops25h 38m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$108
This Super.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:25 am
DEN
- CLT
1 stop29h 24m
Frontier
Deal found 3/15![Frontier logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:06 pm
DEN
- CLT
1 stop22h 22m
Frontier
Deal found 3/15![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:00 pm
DEN
- CHS
1 stop25h 22m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$111
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:59 pm
DEN
- MYR
1 stop9h 49m
Frontier
Deal found 3/16![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
DEN
- CLT
1 stop15h 09m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$111
This Super.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:31 pm
DEN
- CLT
Nonstop3h 23m
Frontier
Deal found 3/11![Frontier logo]()
$112
This Super.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/281:36 pm
DEN
- CLT
Nonstop3h 12m
Frontier
Deal found 3/15![Frontier logo]()
$113
Find flight deals from Colorado to South Carolina
Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated March 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $127 (Super.com) |
One-way from | $104 (Super.com) |
Popular in | January |
Cheapest in | August |
Average price | $453 |
Good round-trip deal | $329 or less |
Good one-way deal | $208 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Wed 4/15
6:35 am-4:10 pm
1 stop7h 35m
Charlotte Douglas
Sat 4/18
12:15 pm-7:10 pm
2 stops8h 55m
$242
DenverMyrtle Beach
DEN - MYR
DENMYR
Denver Intl
Sat 4/25
10:15 am-8:45 pm
2 stops8h 30m
Myrtle Beach Intl
Sat 5/2
7:10 am-2:35 pm
2 stops9h 25m
$281
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Sat 4/18
10:15 am-9:15 pm
2 stops9h 00m
Charlotte Douglas
Mon 4/20
6:15 am-1:30 pm
2 stops9h 15m
$283
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Thu 4/23
12:35 am-9:09 am
1 stop6h 34m
Charlotte Douglas
Fri 4/24
4:54 pm-10:06 pm
1 stop7h 12m
$297
DenverCharleston
DEN - CHS
DENCHS
Denver Intl
Sat 4/11
11:59 pm-10:23 am
1 stop8h 24m
Charleston
Sat 4/18
8:00 am-10:05 am
Nonstop4h 05m
$305
DenverCharleston
DEN - CHS
DENCHS
Denver Intl
Tue 4/28
10:50 am-8:25 pm
2 stops7h 35m
Charleston
Tue 5/5
7:15 am-4:25 pm
2 stops11h 10m
$305
Colorado SpringsCharlotte
COS - CLT
COSCLT
Colorado Springs
Wed 4/29
1:39 pm-9:04 pm
1 stop5h 25m
Charlotte Douglas
Wed 5/6
7:24 pm-11:32 pm
1 stop6h 08m
$309
Colorado SpringsSavannah
COS - SAV
COSSAV
Colorado Springs
Fri 7/31
1:40 pm-8:51 pm
1 stop5h 11m
Savannah/Hilton Head
Tue 8/4
7:00 am-12:59 pm
1 stop7h 59m
$309
DenverMyrtle Beach
DEN - MYR
DENMYR
Denver Intl
Mon 6/8
11:50 pm-9:50 am
1 stop8h 00m
Myrtle Beach Intl
Wed 6/10
7:15 pm-11:40 pm
1 stop6h 25m
$309
DenverSavannah
DEN - SAV
DENSAV
Denver Intl
Mon 5/11
6:35 am-3:50 pm
1 stop7h 15m
Savannah/Hilton Head
Thu 5/14
8:20 pm-11:45 pm
1 stop5h 25m
$309
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Colorado to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
DEN-CLT
DEN-MYR
DEN-CHS
DEN-CAE
COS-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to South Carolina
USCO-USSC
DEN-CLT
DEN-MYR
DEN-CHS
DEN-CAE
What is the cheapest month to book a flight from Colorado to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $154). Flying from Colorado to South Carolina in January is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to SC?
Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.
It’s optimal to fly from Colorado to South Carolina in the evening. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Colorado to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Colorado to South Carolina. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their Colorado to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Colorado to South Carolina
Explore weekly flight availability from Colorado to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 17, 2026.
The most flights from USCO to USSC are scheduled on a Monday (2 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 17, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Colorado to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Colorado to South Carolina by cabin class
Find flights from Colorado to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Colorado and South Carolina flights
Browse other Colorado and South Carolina flight options. Last updated on March 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Colorado after your stay in South Carolina
Colorado to South Carolina flights
Consider these flights traveling from Colorado to South Carolina.
Top 6 airlines flying from Colorado to South Carolina
Discover the top 6 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$78 | Average$249 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$139 | Average$326 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$154 | Average$345 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$171 | Average$454 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$204 | Average$456 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$231 | Average$471 | FlexibilityNo cancel fee | On-time63% |