$124+ Cheap flights from Denver to Greenville (DEN - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — GSP
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Denver Intl to Greenville are usually found in February or March, booked 59 days in advance, depart on a Saturday or Wednesday and return on a Wednesday
Cheap flight deals from Denver to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to GreenvilleExplore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:58 pm -
1 stop12h 34m
Mon 11/168:52 pm -
1 stop13h 32m
Deal found 9/14![Multiple Airlines logo]()
$246
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop4h 45m
Tue 10/137:20 pm -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 am -
1 stop4h 25m
Tue 11/107:05 am -
2 stops9h 05m
Deal found 9/16![Southwest logo]()
$253
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:55 am -
1 stop4h 45m
Thu 10/292:10 pm -
1 stop8h 05m
Deal found 9/14![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop4h 45m
Wed 10/217:00 am -
2 stops7h 50m
Deal found 9/13![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:45 pm -
1 stop6h 15m
Mon 11/166:45 pm -
1 stop5h 55m
Deal found 9/15![Southwest logo]()
$280
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:55 am -
2 stops7h 50m
Fri 12/118:50 pm -
1 stop5h 30m
Deal found 9/14![Southwest logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:58 pm -
1 stop17h 44m
Tue 11/1711:28 am -
1 stop22h 56m
Deal found 9/13![Multiple Airlines logo]()
$295
Best flights from Denver to GreenvilleDiscover carefully curated flight deals from Denver to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Denver to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 am -
1 stop4h 25m
Tue 11/107:05 am -
2 stops9h 05m
Deal found 9/16![Southwest logo]()
$253
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 am -
Nonstop3h 03m
Sun 11/154:29 pm -
Nonstop3h 35m
Deal found 9/12![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop6h 55m
Fri 10/167:14 pm -
1 stop5h 58m
Deal found 9/13![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:30 am -
1 stop11h 05m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/16![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:55 am -
2 stops7h 55m
Sun 11/158:50 pm -
1 stop5h 35m
Deal found 9/14![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop6h 16m
Sat 10/314:29 pm -
Nonstop3h 37m
Deal found 9/16![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:50 am -
2 stops8h 15m
Tue 10/207:00 am -
2 stops7h 50m
Deal found 9/16![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:59 pm -
1 stop7h 49m
Mon 9/284:25 pm -
Nonstop3h 31m
Deal found 9/12![United Airlines logo]()
$574
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:05 pm -
2 stops7h 55m
Sun 11/156:40 am -
2 stops7h 35m
Deal found 9/12![Southwest logo]()
$488
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:10 pm -
1 stop4h 30m
Sat 9/266:45 am -
2 stops7h 00m
Deal found 9/14![Southwest logo]()
$554
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:05 pm -
2 stops6h 45m
Mon 10/128:40 pm -
1 stop5h 45m
Deal found 9/15![Southwest logo]()
$583
Last-minute flights from Denver to GreenvilleDiscover last-minute flight deals from Denver to Greenville. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Greenville. Data last updated September 17, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop4h 45m
Wed 10/217:20 pm -
1 stop5h 10m
Deal found 9/13![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:15 am -
2 stops7h 50m
Tue 10/137:20 pm -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:30 am -
1 stop8h 15m
Wed 10/217:20 pm -
1 stop5h 10m
Deal found 9/13![Southwest logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:56 pm -
1 stop22h 48m
Wed 10/218:24 pm -
1 stop13h 53m
Deal found 9/14![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:56 pm -
1 stop22h 48m
Tue 10/2011:28 am -
1 stop12h 43m
Deal found 9/12![Multiple Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:55 am -
1 stop4h 45m
Tue 10/207:20 pm -
1 stop5h 10m
Deal found 9/16![Southwest logo]()
$313
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:30 am -
1 stop7h 35m
Sat 10/316:40 am -
2 stops10h 40m
Deal found 9/15![Southwest logo]()
$253
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:55 am -
1 stop4h 45m
Thu 10/292:10 pm -
1 stop8h 05m
Deal found 9/14![Southwest logo]()
$264
One-way flights from Denver to GreenvilleSearch for one-way flight options from Denver to Greenville. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Denver to Greenville. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:30 am -
1 stop8h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$124
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:20 am -
1 stop4h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:43 am -
2 stops20h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:31 pm -
3 stops37h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:43 am -
3 stops20h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:10 am -
3 stops25h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:19 pm -
3 stops56h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:19 pm -
3 stops44h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:55 pm -
2 stops34h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$181
Find flight deals from Denver to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $246 (Kiwi.com) |
One-way from | $124 (Southwest) |
Popular in | October |
Cheapest in | February |
Average price | $409 |
Good round-trip deal | $355 or less |
Good one-way deal | $233 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Denver to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Sat 9/26
8:25 am-5:35 pm
2 stops7h 10m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$225
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Wed 10/7
11:15 am-9:05 pm
2 stops7h 50m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$225
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Wed 9/30
8:05 am-7:30 pm
1 stop9h 25m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$225
Quickest round-trip
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Thu 11/5
10:00 am-3:02 pm
Nonstop3h 02m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$245
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Sat 11/7
5:50 am-12:15 pm
1 stop4h 25m
Greenville
Tue 11/10
7:05 am-2:10 pm
2 stops9h 05m
$253
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Wed 9/23
11:15 am-9:00 pm
2 stops7h 45m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$280
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Thu 10/15
10:00 am-3:08 pm
Nonstop3h 08m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$309
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Wed 10/28
10:00 am-3:03 pm
Nonstop3h 03m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$309
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Thu 11/19
10:00 am-3:02 pm
Nonstop3h 02m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$309
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Mon 11/16
10:00 am-3:02 pm
Nonstop3h 02m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$309
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Denver to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Denver-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Denver with our price prediction graph.
DEN-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Greenville
Prices
More
How far ahead should I book a flight from Denver to Greenville?
Booking 57 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to Greenville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Denver to Greenville?
Currently, February is the cheapest month in which you can book a flight from Denver to Greenville (average of $349). Flying from Denver to Greenville in October is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to GSP?
Find hourly flight availability from Denver to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
When flying from Denver to Greenville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from Denver to Greenville?
Share of 1-stop round-trip flights from Denver to Greenville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Dallas (DFW) – chosen by Cheapflights users on 50% of 1-stop itineraries from Denver to Greenville on Cheapflights.
What’s the cheapest layover airport for flights from Denver to Greenville?
Average round-trip fare for 1-stop flights from Denver to Greenville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of $241.
What’s the fastest layover option from Denver to Greenville?
Shortest average travel time for 1-stop one-way flights from Denver to Greenville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Dallas (DFW) have the shortest average one-way travel time for 1-stop routes: 5h 32m.
Which airport typically offers the quickest layover for flights from Denver to Greenville?
Average layover duration for 1-stop one-way flights from Denver to Greenville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Dallas (DFW) offer the fastest connection on this route, with an average layover time of 1h 11m.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 17, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Denver to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Denver to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Other flights to Greenville
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Top 5 airlines flying from Denver to Greenville
Discover the top 5 airlines that operate flights from Denver to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$241 | Average$309 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$249 | Average$436 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$373 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$412 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$292 | Average$406 | FlexibilityNo cancel fee | On-time71% |