South Carolina

$105+ Cheap flights from Denver (DEN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/28. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Jun 8 — Jun 151
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to South Carolina

Cheapest flights from Denver to South Carolina
Explore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:05 am
DEN
-
CLT
1 stop9h 11m
Frontier
Tue 5/268:55 am
CLT
-
DEN
1 stop20h 30m
Frontier
Deal found 5/4$193
This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
DEN
-
CLT
1 stop28h 05m
Frontier
Tue 6/910:01 am
CLT
-
DEN
1 stop11h 57m
Frontier
Deal found 5/5$209
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:56 pm
DEN
-
CLT
1 stop10h 09m
Frontier
Wed 6/1010:20 pm
CLT
-
DEN
1 stop12h 17m
Frontier
Deal found 5/5$210
This deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:00 am
DEN
-
CLT
Nonstop3h 25m
Frontier
Thu 5/286:50 pm
CLT
-
DEN
1 stop6h 54m
Frontier
Deal found 5/4$213
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
DEN
-
CLT
1 stop8h 35m
Frontier
Tue 8/48:02 pm
CLT
-
DEN
1 stop21h 16m
Frontier
Deal found 5/5$217
This deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:00 am
DEN
-
CLT
Nonstop3h 25m
Frontier
Mon 5/255:58 pm
CLT
-
DEN
1 stop8h 00m
Frontier
Deal found 5/4$219
This Trip.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
DEN
-
CLT
1 stop8h 43m
Frontier
Wed 6/1010:14 pm
CLT
-
DEN
Nonstop4h 02m
Frontier
Deal found 5/6$221
This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/133:56 pm
DEN
-
CLT
Nonstop3h 29m
Frontier
Tue 6/167:58 pm
CLT
-
DEN
1 stop14h 22m
Frontier
Deal found 5/5$223
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:25 pm
DEN
-
CLT
1 stop11h 46m
Frontier
Wed 7/2910:14 pm
CLT
-
DEN
Nonstop3h 44m
Frontier
Deal found 5/5$224
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:00 am
DEN
-
CLT
1 stop7h 26m
Frontier
Sat 6/1310:14 pm
CLT
-
DEN
Nonstop4h 02m
Frontier
Deal found 5/5$225
This CheapOair deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
DEN
-
MYR
1 stop6h 46m
Frontier
Sun 5/313:31 pm
MYR
-
DEN
1 stop24h 03m
Frontier
Deal found 5/5$254
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:15 pm
DEN
-
SAV
2 stops20h 36m
Multiple Airlines
Mon 8/244:20 pm
SAV
-
DEN
1 stop9h 39m
Multiple Airlines
Deal found 5/6$255

Find flight deals from Denver to South Carolina

Keep the following information in mind while searching for Denver to South Carolina flight deals. Data was last updated May 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$193
(Kiwi.com)

One-way from

$105
(Frontier)

Popular in

January

Cheapest in

October

Average price

$443

Good round-trip deal

$352 or less

Good one-way deal

$156 or less
Provider with most accurate pricing for Denver Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Denver Intl-Myrtle Beach Intl flights.
From Denver Intl to South Carolina
One-way flight from Denver Intl to South Carolina
Highest demand for flights based on searches. 13% potential increase in price ($66 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in May 2026
Price to beat on a round-trip flight from Denver Intl to South Carolina.
Price to beat on a one-way flight from Denver Intl to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Denver to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverHilton Head Island

DEN - HHH

DENHHH

Denver Intl

Tue 8/11

7:19 am-3:30 pm

1 stop6h 11m

Hilton Head Island

Tue 8/18

12:11 pm-5:55 pm

1 stop7h 44m

$281

DenverHilton Head Island

DEN - HHH

DENHHH

Denver Intl

Thu 7/23

7:15 am-3:29 pm

1 stop6h 14m

Hilton Head Island

Tue 7/28

12:11 pm-10:01 pm

2 stops11h 50m

$306

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Sat 6/6

11:59 pm-9:55 am

1 stop7h 56m

Greenville

Tue 6/9

4:15 pm-5:55 pm

Nonstop3h 40m

$319

DenverSavannah

DEN - SAV

DENSAV

Denver Intl

Tue 9/22

7:40 am-6:20 pm

1 stop8h 40m

Savannah/Hilton Head

Mon 9/28

4:10 pm-6:00 pm

Nonstop3h 50m

$319

DenverCharleston

DEN - CHS

DENCHS

Denver Intl

Tue 6/23

11:59 pm-8:51 am

1 stop6h 52m

Charleston

Tue 6/30

4:16 pm-6:11 pm

Nonstop3h 55m

$321

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Mon 7/13

5:45 am-12:15 pm

1 stop4h 30m

Greenville

Fri 7/17

6:50 pm-11:40 pm

1 stop6h 50m

$329

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 7/2

5:30 am-1:15 pm

1 stop5h 45m

Greenville

Sun 7/5

7:30 pm-12:25 am

1 stop6h 55m

$329

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 6/23

7:15 am-4:10 pm

1 stop6h 55m

Greenville

Wed 7/1

5:16 pm-11:06 pm

1 stop7h 50m

$329

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 6/5

4:41 pm-11:53 pm

1 stop5h 12m

Charlotte Douglas

Sat 6/13

5:39 pm-9:04 pm

1 stop5h 25m

$329

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Sat 7/25

5:45 am-1:31 pm

1 stop5h 46m

Charlotte Douglas

Sun 8/2

5:30 am-8:34 am

1 stop5h 04m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/4

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Denver to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South Carolina

How far ahead should I book a flight from Denver to South Carolina?

Booking 56 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Denver to South Carolina?

Currently, December is the cheapest month in which you can book a flight from Denver to South Carolina (average of $78). Flying from Denver to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SC?

Find hourly flight availability from Denver to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 9, 2026.

A simple way to save on the total cost of your ticket is to fly from Denver to South Carolina at noon. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight in the evening.

Weekly flight availability from Denver to South Carolina

Explore weekly flight availability from Denver to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 9, 2026.

The most flights from DEN to USSC are scheduled on a Monday (2 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Denver to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 9, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Denver to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Denver to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Denver to South Carolina?

    Located just 18.5 mi from the city center, Denver Intl (DEN) is the airport most travelers will use when flying to South Carolina from Denver.

  • How popular is this Denver to South Carolina flight route?

  • How long is the flight from Denver to South Carolina?

    Delta, United Airlines, and Southwest can get you from Denver to South Carolina in just under 4h 30m. Your travel time can differ by up to 3h 26m. Airlines will cover a distance of 1275 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Denver to South Carolina one-way?

    $80 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $99 and $118, respectively.

  • What are the most popular routes from Denver to South Carolina?

  • What are the cheapest flights from Denver to South Carolina?

    Looking for the cheapest flight from Denver to South Carolina? While on average our users pay $396, our data indicates the cheapest price to be $145. The most popular route (Denver Intl - Charlotte Douglas), is priced around $238.

  • Can I find deals for flights from Denver to South Carolina that include hotel bookings?

    Yes. In addition to deals on Denver to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South Carolina.

  • Can I find deals for business class flights from Denver to South Carolina?

    Yes. Cheapflights offers flight deals from Denver to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South Carolina?

    Currently, December is the cheapest month in which you can book a flight from Denver to South Carolina (average of $78). Flying from Denver to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Denver to South Carolina

Discover the top 6 airlines that operate flights from Denver to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$78Average$264FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$139Average$326FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$188Average$390FlexibilityNo cancel feeOn-time71%
DeltaCheapest$207Average$368FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$211Average$442FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$231Average$436FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.