South Carolina

$123+ Cheap flights from Denver (DEN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Jul 28 — Aug 41
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to South Carolina

Cheapest flights from Denver to South Carolina
Explore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:59 am
DEN
-
SAV
1 stop20h 37m
Multiple Airlines
Sun 9/134:06 pm
SAV
-
DEN
1 stop27h 31m
Multiple Airlines
Deal found 6/26$248
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:03 pm
DEN
-
SAV
1 stop14h 44m
Multiple Airlines
Mon 8/314:20 pm
SAV
-
DEN
1 stop9h 21m
Multiple Airlines
Deal found 6/27$267
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
DEN
-
HHH
1 stop6h 03m
United Airlines
Tue 9/82:48 pm
HHH
-
DEN
1 stop8h 56m
United Airlines
Deal found 6/25$281
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:30 am
DEN
-
CLT
2 stops12h 37m
Frontier
Sat 8/810:14 pm
CLT
-
DEN
Nonstop3h 44m
Frontier
Deal found 6/25$287
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:05 am
DEN
-
MYR
2 stops27h 00m
Multiple Airlines
Thu 8/273:59 pm
MYR
-
DEN
1 stop9h 42m
Multiple Airlines
Deal found 6/25$288
This eDestinos deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:56 pm
DEN
-
CLT
Nonstop3h 29m
Frontier
Mon 7/610:04 pm
CLT
-
DEN
Nonstop3h 44m
Frontier
Deal found 6/24$288
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:59 pm
DEN
-
SAV
2 stops39h 53m
Multiple Airlines
Mon 8/244:20 pm
SAV
-
DEN
1 stop9h 21m
Multiple Airlines
Deal found 6/25$290
This Frontier deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:23 pm
DEN
-
CLT
Nonstop3h 23m
Frontier
Fri 9/257:41 pm
CLT
-
DEN
Nonstop4h 00m
Frontier
Deal found 6/26$290
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/212:55 pm
DEN
-
CLT
Nonstop3h 24m
Frontier
Sat 7/2510:14 pm
CLT
-
DEN
Nonstop3h 44m
Frontier
Deal found 6/24$291
This Frontier deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:55 pm
DEN
-
CLT
Nonstop3h 24m
Frontier
Wed 7/110:14 pm
CLT
-
DEN
Nonstop4h 02m
Frontier
Deal found 6/26$292
This Cheapflightsfares deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:55 pm
DEN
-
CLT
Nonstop3h 24m
Frontier
Sun 7/56:05 am
CLT
-
DEN
1 stop10h 53m
Frontier
Deal found 6/24$293
This Super.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:09 am
DEN
-
CLT
1 stop6h 33m
Frontier
Tue 8/412:01 pm
CLT
-
DEN
1 stop7h 50m
Frontier
Deal found 6/27$294

Find flight deals from Denver to South Carolina

Keep the following information in mind while searching for Denver to South Carolina flight deals. Data was last updated June 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$248
(Kiwi.com)

One-way from

$123
(Kiwi.com)

Popular in

January

Cheapest in

October

Average price

$497

Good round-trip deal

$397 or less

Good one-way deal

$246 or less
Provider with most accurate pricing for Denver Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Denver Intl-Myrtle Beach Intl flights.
From Denver Intl to South Carolina
One-way flight from Denver Intl to South Carolina
Highest demand for flights based on searches. 10% potential increase in price ($48 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in June 2026
Price to beat on a round-trip flight from Denver Intl to South Carolina.
Price to beat on a one-way flight from Denver Intl to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Denver to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverHilton Head Island

DEN - HHH

DENHHH

Denver Intl

Sat 9/5

6:00 am-2:03 pm

1 stop6h 03m

Hilton Head Island

Tue 9/8

2:48 pm-9:44 pm

1 stop8h 56m

$281

DenverHilton Head Island

DEN - HHH

DENHHH

Denver Intl

Sat 9/5

6:00 am-2:03 pm

1 stop6h 03m

Hilton Head Island

Wed 9/9

2:48 pm-9:44 pm

1 stop8h 56m

$281

DenverHilton Head Island

DEN - HHH

DENHHH

Denver Intl

Thu 9/3

6:00 am-2:03 pm

1 stop6h 03m

Hilton Head Island

Tue 9/8

2:48 pm-7:45 pm

1 stop6h 57m

$305
Quickest round-trip

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 8/14

9:40 am-2:48 pm

Nonstop3h 08m

Greenville

Thu 8/20

4:33 pm-6:02 pm

Nonstop3h 29m

$309

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 9/15

10:07 am-3:14 pm

Nonstop3h 07m

Greenville

Fri 9/25

4:25 pm-5:56 pm

Nonstop3h 31m

$309

DenverSavannah

DEN - SAV

DENSAV

Denver Intl

Fri 11/6

11:59 pm-10:59 am

1 stop9h 00m

Savannah/Hilton Head

Wed 11/11

4:16 pm-6:11 pm

Nonstop3h 55m

$319

DenverCharlotte

DEN - CLT

DENCLT

Denver Intl

Fri 8/7

5:45 pm-11:08 pm

Nonstop3h 23m

Charlotte Douglas

Tue 8/11

5:58 pm-11:15 pm

1 stop7h 17m

$319

DenverColumbia

DEN - CAE

DENCAE

Denver Intl

Sat 8/1

5:45 am-12:59 pm

1 stop5h 14m

Columbia Metropolitan

Wed 8/5

5:40 am-8:34 am

1 stop4h 54m

$321

DenverColumbia

DEN - CAE

DENCAE

Denver Intl

Wed 8/5

6:13 am-2:16 pm

1 stop6h 03m

Columbia Metropolitan

Wed 8/12

7:54 pm-12:30 am

1 stop6h 36m

$321

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 8/14

1:15 pm-8:32 pm

1 stop5h 17m

Greenville

Thu 8/20

6:58 pm-10:48 pm

1 stop5h 50m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/26

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Denver to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South Carolina

What is the cheapest month to book a flight from Denver to South Carolina?

Currently, December is the cheapest month in which you can book a flight from Denver to South Carolina (average of $78). Flying from Denver to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SC?

Find hourly flight availability from Denver to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 28, 2026.

A simple way to save on the total cost of your ticket is to fly from Denver to South Carolina in the morning. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the evening.

Weekly flight availability from Denver to South Carolina

Explore weekly flight availability from Denver to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 28, 2026.

The most flights from DEN to USSC are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Denver to South Carolina?

How far ahead should I book a flight from Denver to South Carolina?

Booking 70 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 28, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Denver to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Related info for your journey

Find useful and relevant information for your journey from Denver to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Denver to South Carolina?

    Located just 18.5 mi from the city center, Denver Intl (DEN) is the airport most travelers will use when flying to South Carolina from Denver.

  • How popular is this Denver to South Carolina flight route?

  • How long is the flight from Denver to South Carolina?

    United Airlines, Delta, and Southwest can get you from Denver to South Carolina in just under 5h 14m. Your travel time can differ by up to 2h 16m. Airlines will cover a distance of 1358 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Denver to South Carolina one-way?

    $75 is the cheapest one-way deal found within the past few days, from Viva. You may also be able to find cheap deals on Volaris and Frontier, with prices starting from $76 and $81, respectively.

  • What are the most popular routes from Denver to South Carolina?

  • What are the cheapest flights from Denver to South Carolina?

    Looking for the cheapest flight from Denver to South Carolina? While on average our users pay $437, our data indicates the cheapest price to be $160. The most popular route (Denver Intl - Charlotte Douglas), is priced around $235.

  • Can I find deals for flights from Denver to South Carolina that include hotel bookings?

    Yes. In addition to deals on Denver to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South Carolina.

  • Can I find deals for business class flights from Denver to South Carolina?

    Yes. Cheapflights offers flight deals from Denver to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South Carolina?

    Currently, December is the cheapest month in which you can book a flight from Denver to South Carolina (average of $78). Flying from Denver to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 6 airlines flying from Denver to South Carolina

Discover the top 6 airlines that operate flights from Denver to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$139Average$274FlexibilityNo cancel feeOn-time62%
FrontierCheapest$185Average$261FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$198Average$404FlexibilityNo cancel feeOn-time71%
DeltaCheapest$207Average$387FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$211Average$434FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$231Average$441FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.