$117+ Cheap flights from Denver (DEN) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Oct 24 — Oct 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Denver to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to South CarolinaExplore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Denver to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Sat 10/244:00 pm -
Nonstop3h 58m
Deal found 9/23![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:59 am -
1 stop7h 08m
Wed 10/216:58 pm -
1 stop5h 34m
Deal found 9/22![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:30 pm -
2 stops7h 35m
Sat 11/73:55 pm -
1 stop6h 00m
Deal found 9/23![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:59 am -
1 stop7h 08m
Tue 10/206:58 pm -
1 stop5h 34m
Deal found 9/19![Delta logo]()
$298
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:59 pm -
1 stop7h 30m
Tue 10/205:00 pm -
1 stop8h 53m
Deal found 9/20![United Airlines logo]()
$302
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Tue 10/2010:38 am -
1 stop6h 59m
Deal found 9/23![United Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
Nonstop3h 26m
Mon 11/24:15 pm -
Nonstop3h 59m
Deal found 9/21![United Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:40 am -
1 stop19h 58m
Sat 10/316:00 am -
1 stop18h 16m
Deal found 9/20![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:02 pm -
1 stop11h 36m
Wed 10/289:03 pm -
1 stop17h 46m
Deal found 9/20![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:02 pm -
1 stop11h 36m
Tue 10/203:18 pm -
1 stop18h 49m
Deal found 9/21![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:02 pm -
1 stop11h 36m
Tue 10/203:18 pm -
1 stop18h 49m
Deal found 9/21![Multiple Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:30 pm -
2 stops7h 50m
Mon 11/98:55 pm -
1 stop5h 30m
Deal found 9/21![Southwest logo]()
$315
Best flights from Denver to South CarolinaDiscover carefully curated flight deals from Denver to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Denver to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:30 pm -
2 stops7h 35m
Fri 11/138:55 pm -
1 stop5h 30m
Deal found 9/22![Southwest logo]()
$282
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:59 pm -
1 stop7h 43m
Tue 10/2711:27 am -
1 stop10h 33m
Deal found 9/24![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:59 am -
1 stop7h 08m
Mon 10/266:58 pm -
1 stop6h 14m
Deal found 9/19![Delta logo]()
$348
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops9h 38m
Mon 11/235:47 pm -
1 stop7h 19m
Deal found 9/22![American Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:10 pm -
1 stop7h 30m
Mon 12/76:25 pm -
1 stop6h 10m
Deal found 9/21![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:59 pm -
1 stop7h 43m
Tue 10/205:00 pm -
1 stop8h 53m
Deal found 9/22![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:59 am -
1 stop7h 44m
Mon 10/195:59 pm -
1 stop7h 13m
Deal found 9/20![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:30 pm -
2 stops7h 35m
Thu 11/127:35 pm -
1 stop6h 20m
Deal found 9/20![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:00 am -
Nonstop3h 03m
Sat 11/144:29 pm -
Nonstop3h 37m
Deal found 9/22![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:07 pm -
1 stop4h 44m
Mon 12/145:35 am -
1 stop8h 31m
Deal found 9/21![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:25 am -
2 stops7h 45m
Sat 11/147:05 am -
2 stops6h 20m
Deal found 9/22![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:59 pm -
1 stop7h 13m
Thu 11/54:15 pm -
Nonstop3h 59m
Deal found 9/21![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:05 pm -
1 stop9h 30m
Sun 11/85:30 am -
1 stop6h 10m
Deal found 9/23![Southwest logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:24 am -
1 stop5h 58m
Wed 10/75:59 pm -
1 stop6h 59m
Deal found 9/19![American Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop7h 10m
Wed 10/145:00 pm -
1 stop8h 54m
Deal found 9/22![United Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop5h 14m
Tue 10/273:53 pm -
1 stop7h 34m
Deal found 9/22![Delta logo]()
$508
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:59 pm -
1 stop7h 43m
Thu 10/155:00 pm -
1 stop8h 54m
Deal found 9/23![United Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:35 am -
2 stops9h 35m
Tue 10/202:10 pm -
2 stops10h 05m
Deal found 9/22![Southwest logo]()
$440
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:05 pm -
2 stops6h 40m
Fri 10/306:15 am -
2 stops8h 40m
Deal found 9/23![Southwest logo]()
$440
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:43 pm -
2 stops15h 16m
Fri 10/166:08 pm -
1 stop6h 50m
Deal found 9/19![American Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:45 am -
Nonstop3h 21m
Thu 12/34:18 pm -
Nonstop4h 00m
Deal found 9/19![United Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 27m
Mon 10/512:17 pm -
1 stop5h 58m
Deal found 9/22![Delta logo]()
$595
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:00 am -
2 stops8h 05m
Thu 12/38:00 am -
2 stops7h 45m
Deal found 9/19![Southwest logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:59 pm -
1 stop8h 07m
Mon 11/94:15 pm -
Nonstop3h 59m
Deal found 9/23![United Airlines logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:20 pm -
Nonstop3h 26m
Wed 10/214:13 pm -
Nonstop3h 49m
Deal found 9/23![United Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:30 am -
1 stop5h 56m
Thu 10/156:08 pm -
1 stop6h 50m
Deal found 9/23![American Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
1 stop7h 10m
Tue 10/205:00 pm -
1 stop8h 53m
Deal found 9/22![United Airlines logo]()
$461
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:59 pm -
1 stop8h 00m
Thu 11/2610:37 am -
1 stop6h 40m
Deal found 9/23![United Airlines logo]()
$465
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 am -
2 stops8h 15m
Sun 10/256:15 am -
2 stops6h 50m
Deal found 9/23![Southwest logo]()
$565
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:30 pm -
2 stops7h 15m
Fri 11/278:50 pm -
1 stop5h 35m
Deal found 9/20![Southwest logo]()
$576
Last-minute flights from Denver to South CarolinaDiscover last-minute flight deals from Denver to South Carolina. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to South Carolina. Data last updated September 24, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:59 am -
1 stop7h 08m
Wed 10/216:58 pm -
1 stop5h 34m
Deal found 9/19![Delta logo]()
$298
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:59 am -
1 stop7h 08m
Thu 10/226:58 pm -
1 stop6h 14m
Deal found 9/22![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:59 pm -
1 stop7h 30m
Tue 10/205:00 pm -
1 stop8h 53m
Deal found 9/20![United Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:02 pm -
1 stop11h 36m
Tue 10/203:18 pm -
1 stop18h 49m
Deal found 9/21![Multiple Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Sat 10/244:00 pm -
Nonstop3h 58m
Deal found 9/23![United Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Tue 10/2010:38 am -
1 stop6h 59m
Deal found 9/23![United Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:02 pm -
1 stop11h 36m
Tue 10/203:18 pm -
1 stop18h 49m
Deal found 9/21![Multiple Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
Nonstop3h 26m
Mon 11/24:15 pm -
Nonstop3h 59m
Deal found 9/21![United Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:40 am -
1 stop23h 58m
Thu 10/298:27 pm -
2 stops37h 55m
Deal found 9/20![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:02 pm -
1 stop11h 36m
Wed 10/289:03 pm -
1 stop17h 46m
Deal found 9/20![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:40 am -
1 stop19h 58m
Sat 10/316:00 am -
1 stop18h 16m
Deal found 9/20![Multiple Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:45 am -
1 stop4h 50m
Wed 11/43:25 pm -
2 stops9h 15m
Deal found 9/20![Southwest logo]()
$282
One-way flights from Denver to South CarolinaSearch for one-way flight options from Denver to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Denver to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:20 pm -
Nonstop3h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:12 pm -
1 stop11h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$119
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:30 am -
1 stop12h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Southwest logo]()
$121
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:59 pm -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$127
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:35 am -
Nonstop3h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$129
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:20 am -
2 stops7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Southwest logo]()
$132
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:50 pm -
Nonstop3h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Southwest logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:31 pm -
2 stops36h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:10 am -
2 stops24h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$138
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:59 am -
1 stop7h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Delta logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:10 am -
2 stops24h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:30 am -
2 stops28h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$143
Find flight deals from Denver to South Carolina
Keep the following information in mind while searching for Denver to South Carolina flight deals. Data was last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $231 (Southwest) |
One-way from | $117 (Southwest) |
Popular in | March |
Cheapest in | January |
Average price | $410 |
Good round-trip deal | $355 or less |
Good one-way deal | $203 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Denver to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Sat 10/17
3:20 pm-8:40 pm
Nonstop3h 20m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$117
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Sat 10/17
5:30 am-7:35 pm
1 stop12h 05m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$121
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Sat 10/17
6:00 am-2:04 pm
1 stop6h 04m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$127
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Tue 10/13
11:59 pm-9:14 am
1 stop7h 15m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$127
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Wed 11/18
8:35 am-5:25 pm
1 stop6h 50m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$127
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Sat 12/5
8:50 am-6:05 pm
2 stops7h 15m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$132
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Sat 10/31
6:20 am-3:40 pm
2 stops7h 20m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$132
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Fri 10/16
12:59 am-10:07 am
1 stop7h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sun 10/18
12:59 am-10:42 am
1 stop7h 43m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sat 10/17
11:59 pm-9:42 am
1 stop7h 43m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Denver to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Denver with our price prediction graph.
DEN-MYR
DEN-CHS
DEN-HHH
DEN-CAE
DEN-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to South Carolina
DEN-USSC
DEN-MYR
DEN-CHS
DEN-HHH
DEN-CAE
What is the cheapest month to book a flight from Denver to South Carolina?
Currently, April is the cheapest month in which you can book a flight from Denver to South Carolina (average of $392). Flying from Denver to South Carolina in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to SC?
Find hourly flight availability from Denver to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 24, 2026.
A simple way to save on the total cost of your ticket is to fly from Denver to South Carolina at noon. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight in the evening.
How much does it cost to fly round-trip from Denver to South Carolina?
Airfare is below average for this route at the moment.
Denver to South Carolina flights typically cost between $337 and $544 in October.The cheapest round-trip price found within the last 5 days was $308 on United Airlines (Oct 21-Nov 2).
How far ahead should I book a flight from Denver to South Carolina?
Booking 72 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 24, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Denver to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Denver to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Denver to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to South Carolina by cabin class
Find flights from Denver to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and South Carolina flights
Browse other Denver and South Carolina flight options. Last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Denver to South Carolina flights
Consider these flights traveling from Denver to South Carolina.
Top 6 airlines flying from Denver to South Carolina
Discover the top 6 airlines that operate flights from Denver to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$155 | Average$260 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$208 | Average$318 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$211 | Average$439 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$244 | Average$389 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$426 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$449 | FlexibilityNo cancel fee | On-time63% |