South America

$162+ Cheap flights from Wilmington (ILM) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — BOG
Jan 11 — Jan 181
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Cheap flight deals from Wilmington to South America

Cheapest flights from Wilmington to South America
Explore the most affordable flight options available from Wilmington to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:17 pmILM - MDE
1 stop10h 11mMultiple Airlines
Sun 1/411:50 amMDE - ILM
1 stop20h 40mMultiple Airlines
Deal found 12/10$1,197

Find flight deals from Wilmington to South America

Keep the following information in mind while searching for Wilmington to South America flight deals. Data was last updated December 12, 2025.

Round-trip from

$426
(Mytrip)

One-way from

$162
(Kiwi.com)
From Wilmington New Hanover County to South America
One-way flight from Wilmington New Hanover County to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Wilmington to South America that are best for you.

Fly from

Wilmington

Fly to

South America

Route

Depart

Return

Price

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 2/19

5:30 pm-2:13 pm

2 stops20h 43m

Medellín Jose Maria Cordova Intl

Mon 2/23

3:15 pm-11:12 pm

1 stop7h 57m

$426

WilmingtonBogotá

ILM - BOG

ILMBOG

Wilmington New Hanover County

Mon 2/2

6:00 am-7:30 pm

1 stop13h 30m

Bogotá El Dorado

Thu 2/5

9:00 am-11:51 pm

1 stop14h 51m

$493

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/29

2:25 pm-2:15 pm

2 stops23h 50m

Medellín Jose Maria Cordova Intl

Mon 2/2

1:00 pm-8:20 pm

1 stop7h 20m

$497

WilmingtonBogotá

ILM - BOG

ILMBOG

Wilmington New Hanover County

Sun 1/25

10:23 am-7:30 pm

1 stop9h 07m

Bogotá El Dorado

Sun 2/1

9:00 am-4:56 pm

1 stop7h 56m

$583

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 2/5

5:01 pm-1:55 pm

1 stop20h 54m

Medellín Jose Maria Cordova Intl

Mon 2/9

1:00 pm-8:20 pm

1 stop7h 20m

$589

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/15

2:25 pm-8:18 am

2 stops41h 53m

Medellín Jose Maria Cordova Intl

Mon 1/19

1:00 pm-8:20 pm

1 stop7h 20m

$591

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/29

6:00 am-9:10 pm

2 stops15h 10m

Medellín Jose Maria Cordova Intl

Mon 2/2

7:00 am-10:57 pm

2 stops15h 57m

$620

WilmingtonQuito

ILM - UIO

ILMUIO

Wilmington New Hanover County

Thu 3/12

6:00 am-10:23 pm

1 stop17h 23m

Quito Mariscal Sucr

Mon 3/23

6:30 am-7:12 pm

1 stop11h 42m

$626

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/8

6:00 am-2:03 pm

1 stop8h 03m

Medellín Jose Maria Cordova Intl

Mon 1/12

3:10 pm-11:57 pm

1 stop8h 47m

$637

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 2/5

6:30 am-9:10 pm

2 stops14h 40m

Medellín Jose Maria Cordova Intl

Mon 2/9

3:10 pm-10:42 am

2 stops19h 32m

$642

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 44 results
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Best time to book a flight from Wilmington to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to South America

What is the cheapest time of day to fly from ILM to SA?

Find hourly flight availability from Wilmington to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s typically best to fly out from Wilmington to South America in the evening. Doing so could potentially save you 56% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Wilmington to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Wilmington to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Wilmington to South America?

    Wilmington New Hanover County (ILM), located 4.3 mi from the city center, is the airport you fly out of when you book flights from Wilmington to South America.

  • How long is the flight from Wilmington to South America?

    For as low as $493, LATAM Airlines can have you in South America from Wilmington in 13h 30m. Wilmington and South America are separated by a distance of 2056 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Wilmington to South America?

  • Can I find deals for flights from Wilmington to South America that include hotel bookings?

    Yes. In addition to deals on Wilmington to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to South America.

  • Can I find deals for business class flights from Wilmington to South America?

    Yes. Cheapflights offers flight deals from Wilmington to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Wilmington to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Wilmington to South America

Discover the top 2 airlines that operate flights from Wilmington to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$454Average$1,176FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$533Average$722FlexibilityNo cancel feeOn-time71%

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