HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$740+ Cheap flights from Wilmington (ILM) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — BOG
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Wilmington to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Wilmington to South America

Keep the following information in mind while searching for Wilmington to South America flight deals. Data was last updated September 15, 2025.

Round-trip from

$740
(American Airlines)
From Wilmington New Hanover County to South America
Search Deals

Find flight deals from Wilmington to South America

Cheapest flights from Wilmington to South America
Explore the most affordable flight options available from Wilmington to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:00 amILM - UIO
1 stop17h 04mAmerican Airlines
Sun 11/308:27 amUIO - ILM
1 stop15h 41mAmerican Airlines
Deal found 9/13$740
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amILM - SCL
2 stops22h 45mDelta
Tue 10/149:40 pmSCL - ILM
1 stop20h 30mDelta
Deal found 9/14$754
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:00 amILM - MDE
1 stop9h 06mAmerican Airlines
Mon 1/51:25 amMDE - ILM
1 stop17h 34mAmerican Airlines
Deal found 9/14$814
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:56 pmILM - MDE
2 stops19h 10mAmerican Airlines
Mon 1/51:25 amMDE - ILM
2 stops22h 00mAmerican Airlines
Deal found 9/14$818
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:24 pmILM - MDE
2 stops17h 42mAmerican Airlines
Sun 1/41:30 amMDE - ILM
2 stops16h 23mAmerican Airlines
Deal found 9/14$843
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:00 amILM - MDE
1 stop9h 06mAmerican Airlines
Wed 1/71:25 amMDE - ILM
1 stop21h 38mAmerican Airlines
Deal found 9/14$847
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:56 pmILM - MDE
2 stops19h 10mAmerican Airlines
Wed 1/71:25 amMDE - ILM
1 stop21h 38mAmerican Airlines
Deal found 9/14$851
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:41 amILM - MDE
2 stops31h 25mAmerican Airlines
Sun 1/41:30 amMDE - ILM
2 stops16h 23mAmerican Airlines
Deal found 9/14$863
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:26 pmILM - MDE
2 stops30h 13mAmerican Airlines
Mon 1/51:25 amMDE - ILM
2 stops22h 00mAmerican Airlines
Deal found 9/14$885
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:00 amILM - BOG
1 stop17h 10mAmerican Airlines
Mon 1/51:40 pmBOG - ILM
1 stop11h 07mAmerican Airlines
Deal found 9/14$963
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:21 pmILM - GRU
1 stop14h 19mDelta
Fri 10/314:25 pmGRU - ILM
2 stops24h 19mDelta
Deal found 9/14$1,270
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/111:21 pmILM - GRU
2 stops17h 59mAmerican Airlines
Sat 10/1811:15 pmGRU - ILM
2 stops15h 49mAmerican Airlines
Deal found 9/12$1,275

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Wilmington to South America that are best for you.

Fly from

Wilmington

Fly to

South America

Route

Depart

Return

Price

WilmingtonQuito

ILM - UIO

ILMUIO

Wilmington New Hanover County

Sat 11/22

6:00 am-11:04 pm

1 stop17h 04m

Quito Mariscal Sucr

Sun 11/30

8:27 am-12:08 am

1 stop15h 41m

$740

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Sat 10/11

6:00 am-2:51 pm

2 stops31h 51m

Santiago Arturo Merino Benitez

Tue 10/14

4:35 pm-10:39 pm

2 stops31h 04m

$754

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Sat 10/11

6:00 am-5:45 am

2 stops22h 45m

Santiago Arturo Merino Benitez

Tue 10/14

9:40 pm-5:10 pm

1 stop20h 30m

$754

WilmingtonSantiago

ILM - SCL

ILMSCL

Wilmington New Hanover County

Sun 1/18

11:45 am-6:40 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Wed 2/4

4:35 am-11:54 pm

2 stops21h 19m

$754

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Mon 12/22

6:56 pm-2:06 pm

2 stops19h 10m

Medellín Jose Maria Cordova Intl

Mon 1/5

1:25 am-11:25 pm

2 stops22h 00m

$818

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Tue 12/23

5:00 am-2:06 pm

1 stop9h 06m

Medellín Jose Maria Cordova Intl

Wed 1/7

1:25 am-3:40 pm

2 stops14h 15m

$838

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Tue 12/23

5:00 am-2:06 pm

1 stop9h 06m

Medellín Jose Maria Cordova Intl

Sun 1/4

1:30 am-5:53 pm

2 stops16h 23m

$843

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Mon 12/22

6:56 pm-2:06 pm

2 stops19h 10m

Medellín Jose Maria Cordova Intl

Wed 1/7

1:25 am-11:03 pm

1 stop21h 38m

$851

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Tue 12/23

5:00 am-2:06 pm

1 stop9h 06m

Medellín Jose Maria Cordova Intl

Tue 1/6

1:25 am-8:19 pm

2 stops18h 54m

$909

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Mon 12/22

8:24 pm-2:06 pm

2 stops17h 42m

Medellín Jose Maria Cordova Intl

Tue 1/6

1:25 am-8:19 pm

2 stops18h 54m

$909

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 28 results
1
2
3

Best time to book a flight from Wilmington to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to South America

What is the cheapest time of day to fly from ILM to SA?

Find hourly flight availability from Wilmington to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Wilmington to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Wilmington to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,956 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,956 reviews
Delta
8.0
Very good
7,956 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,956 reviews

Food

7.3

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Wilmington to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Wilmington to South America?

    Wilmington New Hanover County (ILM), located 4.3 mi from the city center, is the airport you fly out of when you book flights from Wilmington to South America.

  • How long is the flight from Wilmington to South America?

    For as low as $740, American Airlines can have you in South America from Wilmington in 17h 04m. Wilmington and South America are separated by a distance of 2375 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Wilmington to South America?

    When deciding which route to take from Wilmington to South America consider Wilmington New Hanover County - Buenos Aires Ministro Pistarini, Wilmington New Hanover County - Sao Paulo Guarulhos Intl or Wilmington New Hanover County - Santiago Arturo Merino Benitez as they are the most popular.

  • Can I find deals for flights from Wilmington to South America that include hotel bookings?

    Yes. In addition to deals on Wilmington to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to South America.

  • Can I find deals for business class flights from Wilmington to South America?

    Yes. Cheapflights offers flight deals from Wilmington to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilmington to South America?

    Currently, May is the cheapest month in which you can book a flight from Wilmington to South America (average of $359). Flying from Wilmington to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Wilmington to South America

See prices for flight routes from nearby airports that may be better suited for you.
Raleigh to John F Kennedy Intl flights
Raleigh to LaGuardia flights
Charlotte to John F Kennedy Intl flights
Raleigh to Las Vegas flights
Raleigh to Miami flights
Raleigh to Newark flights
Raleigh to Boston flights
Charlotte to LaGuardia flights
Charlotte to Las Vegas flights
Charlotte to Denver flights
Charlotte to Newark flights
Charlotte to Boston flights
Raleigh to Orlando flights
Raleigh to O'Hare Intl flights
Raleigh to Denver flights
Charlotte to O'Hare Intl flights
Charlotte to Dallas/Fort Worth flights
Raleigh to Atlanta flights
Charlotte to Orlando flights
Charlotte to Hobby flights
Raleigh to Hobby flights
Raleigh to Luis Munoz Marin Intl flights
Raleigh to Sky Harbor Intl flights
Raleigh to Los Angeles flights
Charlotte to Cancún flights
Raleigh to Fort Lauderdale flights
Raleigh to Nashville flights
Charlotte to Fort Lauderdale flights
Raleigh to San Francisco flights
Charlotte to Sky Harbor Intl flights
Charlotte to George Bush Intcntl flights
Charlotte to Miami flights
Raleigh to Dallas/Fort Worth flights
Raleigh to Cancún flights
Raleigh to George Bush Intcntl flights
Norfolk to Atlanta flights
Charlotte to Luis Munoz Marin Intl flights
Charlotte to Dulles Intl flights
Charlotte to Baltimore flights
Charlotte to Seattle flights
Raleigh to Heathrow flights
Charlotte to Los Angeles flights
Raleigh to Detroit flights
Raleigh to Tampa flights
Charlotte to Heathrow flights
Knoxville to LaGuardia flights
Raleigh to Austin flights
Raleigh to Dulles Intl flights
Raleigh to Seattle flights
Charlotte to Love Field flights

Top 2 airlines flying from Wilmington to South America

Discover the top 2 airlines that operate flights from Wilmington to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$454Average$1,098FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$533Average$724FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.