How long is the flight from Wilmington to South America?

For as low as $493, LATAM Airlines can have you in South America from Wilmington in 13h 30m. Wilmington and South America are separated by a distance of 2056 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in South America ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit South America when rainfall is around 2.0 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

What are the most popular routes from Wilmington to South America?

When deciding which route to take from Wilmington to South America consider Wilmington New Hanover County - Medellín Jose Maria Cordova Intl, Wilmington New Hanover County - Quito Mariscal Sucr or Wilmington New Hanover County - Santiago Arturo Merino Benitez as they are the most popular.

What airport do you fly from for flights from Wilmington to South America?

Wilmington New Hanover County (ILM), located 4.3 mi from the city center, is the airport you fly out of when you book flights from Wilmington to South America.

Can I find deals for flights from Wilmington to South America that include hotel bookings?

Yes. In addition to deals on Wilmington to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Wilmington to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to South America.

Can I find deals for business class flights from Wilmington to South America?

Yes. Cheapflights offers flight deals from Wilmington to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$162+ Flights from Wilmington to South America

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Cheap flight deals from Wilmington to South America

Cheapest flights from Wilmington to South America
Explore the most affordable flight options available from Wilmington to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Fri 12/263:17 pmILM - MDE

1 stop10h 11mMultiple Airlines

Sun 1/411:50 amMDE - ILM

1 stop20h 40mMultiple Airlines

Deal found 12/10

$1,197

Best flights from Wilmington to South America
Discover carefully curated flight deals from Wilmington to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Thu 2/195:30 pmILM - MDE

2 stops20h 43mMultiple Airlines

Mon 2/233:15 pmMDE - ILM

1 stop7h 57mMultiple Airlines

Deal found 12/10

$426

Mon 2/26:00 amILM - BOG

1 stop13h 30mLATAM Airlines

Thu 2/59:00 amBOG - ILM

1 stop14h 51mLATAM Airlines

Deal found 12/11

$493

Thu 1/296:00 amILM - MDE

2 stops15h 10mAmerican Airlines

Mon 2/27:00 amMDE - ILM

2 stops15h 57mAmerican Airlines

Deal found 12/10

$620

Sun 1/1810:37 amILM - SCL

1 stop17h 33mDelta

Thu 2/511:10 pmSCL - ILM

1 stop19h 46mDelta

Deal found 12/10

$754

Thu 1/292:25 pmILM - MDE

2 stops23h 50mMultiple Airlines

Mon 2/21:00 pmMDE - ILM

1 stop7h 20mMultiple Airlines

Deal found 12/10

$497

Sun 1/2510:23 amILM - BOG

1 stop9h 07mLATAM Airlines

Sun 2/19:00 amBOG - ILM

1 stop7h 56mLATAM Airlines

Deal found 12/11

$583

Wed 1/284:26 pmILM - GRU

2 stops15h 54mUnited Airlines

Mon 2/210:25 pmGRU - ILM

2 stops27h 34mUnited Airlines

Deal found 12/9

$1,205

Thu 3/126:00 amILM - UIO

1 stop17h 23mAmerican Airlines

Mon 3/236:30 amUIO - ILM

1 stop11h 42mAmerican Airlines

Deal found 12/11

$626

Thu 2/55:01 pmILM - MDE

1 stop20h 54mMultiple Airlines

Mon 2/91:00 pmMDE - ILM

1 stop7h 20mMultiple Airlines

Deal found 12/10

$589

Thu 1/86:00 amILM - MDE

1 stop8h 03mAmerican Airlines

Mon 1/123:10 pmMDE - ILM

1 stop8h 47mAmerican Airlines

Deal found 12/10

$637

Thu 1/152:25 pmILM - MDE

2 stops41h 53mMultiple Airlines

Mon 1/191:00 pmMDE - ILM

1 stop7h 20mMultiple Airlines

Deal found 12/10

$591

Thu 2/56:30 amILM - MDE

2 stops14h 40mAmerican Airlines

Mon 2/93:10 pmMDE - ILM

2 stops19h 32mAmerican Airlines

Deal found 12/10

$642

Thu 1/2210:23 amILM - UIO

2 stops12h 37mLATAM Airlines

Mon 1/267:00 pmUIO - ILM

2 stops28h 51mLATAM Airlines

Deal found 12/11

$727

Thu 3/121:15 pmILM - UIO

3 stops29h 40mMultiple Airlines

Mon 3/232:20 pmUIO - ILM

2 stops30h 46mMultiple Airlines

Deal found 12/11

$652

Fri 3/206:00 amILM - SCL

2 stops23h 35mLATAM Airlines

Tue 3/248:50 amSCL - ILM

2 stops25h 55mLATAM Airlines

Deal found 12/9

$754

Wed 1/76:00 amILM - UIO

2 stops17h 47mAmerican Airlines

Fri 5/226:40 amUIO - ILM

1 stop10h 38mAmerican Airlines

Deal found 12/9

$732

Sun 1/184:30 pmILM - SCL

2 stops19h 35mLATAM Airlines

Thu 2/58:10 amSCL - ILM

2 stops17h 41mLATAM Airlines

Deal found 12/11

$754

Tue 1/66:00 amILM - UIO

2 stops17h 47mAmerican Airlines

Thu 5/2111:40 pmUIO - ILM

1 stop17h 38mAmerican Airlines

Deal found 12/9

$847

Wed 2/44:26 pmILM - GRU

1 stop14h 29mUnited Airlines

Sun 2/89:45 pmGRU - ILM

2 stops19h 59mUnited Airlines

Deal found 12/9

$1,245

Fri 2/62:32 pmILM - GRU

1 stop13h 08mDelta

Tue 2/109:15 pmGRU - ILM

1 stop14h 18mDelta

Deal found 12/9

$1,270

Wed 3/46:00 amILM - GRU

2 stops23h 15mUnited Airlines

Sun 3/810:15 pmGRU - ILM

2 stops24h 58mUnited Airlines

Deal found 12/10

$1,245

Sat 2/74:48 pmILM - GRU

1 stop14h 47mDelta

Thu 2/129:15 pmGRU - ILM

1 stop14h 13mDelta

Deal found 12/9

$1,270

Tue 2/32:32 pmILM - GRU

1 stop13h 08mDelta

Sat 2/79:15 pmGRU - ILM

1 stop14h 18mDelta

Deal found 12/9

$1,270

Sat 2/2811:46 amILM - GRU

2 stops17h 44mLATAM Airlines

Sat 3/79:15 pmGRU - ILM

1 stop13h 30mLATAM Airlines

Deal found 12/10

$1,112

Sat 2/287:33 pmILM - GRU

1 stop11h 17mAmerican Airlines

Fri 3/612:15 amGRU - ILM

1 stop20h 43mAmerican Airlines

Deal found 12/10

$1,120

Wed 3/44:27 pmILM - VCP

2 stops24h 53mUnited Airlines

Sun 3/810:45 pmVCP - ILM

2 stops24h 28mUnited Airlines

Deal found 12/9

$7,014

Last-minute flights from Wilmington to South America
Discover last-minute flight deals from Wilmington to South America. Data last updated December 12, 2025 and is based on user searches.

Tue 1/66:00 amILM - UIO

2 stops17h 47mAmerican Airlines

Thu 5/2111:40 pmUIO - ILM

1 stop17h 38mAmerican Airlines

Deal found 12/9

$847

Tue 1/66:00 amILM - UIO

2 stops17h 47mAmerican Airlines

Fri 5/226:40 amUIO - ILM

1 stop10h 38mAmerican Airlines

Deal found 12/9

$860

Wed 1/76:00 amILM - UIO

2 stops17h 47mAmerican Airlines

Fri 5/226:40 amUIO - ILM

1 stop10h 38mAmerican Airlines

Deal found 12/9

$732

Thu 1/86:00 amILM - MDE

1 stop8h 03mAmerican Airlines

Mon 1/123:10 pmMDE - ILM

1 stop8h 47mAmerican Airlines

Deal found 12/10

$637

Thu 1/85:41 pmILM - UIO

2 stops11h 36mDelta

Thu 5/217:00 pmUIO - ILM

2 stops39h 09mDelta

Deal found 12/9

$901

Thu 1/810:37 amILM - UIO

2 stops18h 40mDelta

Sat 5/237:00 pmUIO - ILM

2 stops20h 28mDelta

Deal found 12/9

$909

Thu 1/152:25 pmILM - MDE

2 stops41h 53mMultiple Airlines

Mon 1/191:00 pmMDE - ILM

1 stop7h 20mMultiple Airlines

Deal found 12/10

$591

Sun 1/1810:37 amILM - SCL

2 stops26h 53mDelta

Thu 2/56:30 pmSCL - ILM

2 stops17h 03mDelta

Deal found 12/10

$754

Thu 1/2210:23 amILM - UIO

2 stops12h 37mLATAM Airlines

Mon 1/267:00 pmUIO - ILM

2 stops28h 51mLATAM Airlines

Deal found 12/11

$727

Sun 1/2510:23 amILM - BOG

1 stop9h 07mLATAM Airlines

Sun 2/19:00 amBOG - ILM

1 stop7h 56mLATAM Airlines

Deal found 12/11

$583

Thu 1/292:25 pmILM - MDE

2 stops23h 50mMultiple Airlines

Mon 2/21:00 pmMDE - ILM

1 stop7h 20mMultiple Airlines

Deal found 12/10

$497

Thu 1/296:00 amILM - MDE

2 stops15h 10mAmerican Airlines

Mon 2/27:00 amMDE - ILM

2 stops15h 57mAmerican Airlines

Deal found 12/10

$620

One-way flights from Wilmington to South America
Search for one-way flight options from Wilmington to South America. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Tue 12/3010:45 amILM - MDE

1 stop24h 10mMultiple Airlines

Deal found 12/10

$162

Mon 12/299:10 amILM - MDE

2 stops16h 18mMultiple Airlines

Deal found 12/10

$204

Thu 1/85:01 pmILM - UIO

3 stops24h 54mMultiple Airlines

Deal found 12/9

$280

Sun 12/284:42 pmILM - MDE

1 stop18h 13mMultiple Airlines

Deal found 12/10

$295

Wed 12/316:00 amILM - MDE

2 stops32h 10mDelta

Deal found 12/10

$333

Fri 12/263:17 pmILM - MDE

1 stop10h 11mMultiple Airlines

Deal found 12/10

$380

Wed 12/315:05 amILM - MDE

2 stops16h 05mAmerican Airlines

Deal found 12/10

$397

Wed 1/76:00 amILM - UIO

2 stops17h 47mAmerican Airlines

Deal found 12/9

$404

Tue 12/306:00 amILM - MDE

2 stops20h 05mLATAM Airlines

Deal found 12/10

$472

Tue 1/63:58 pmILM - UIO

2 stops31h 49mAmerican Airlines

Deal found 12/9

$474

Thu 1/87:38 pmILM - UIO

1 stop28h 09mAmerican Airlines

Deal found 12/9

$497

Tue 1/272:32 pmILM - SCL

1 stop15h 08mDelta

Deal found 12/10

$518

Find flight deals from Wilmington to South America

Round-trip from	$426 (Mytrip)
One-way from	$162 (Kiwi.com)

From Wilmington New Hanover County to South America

Search Deals

One-way flight from Wilmington New Hanover County to South America

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Wilmington to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 2/19

5:30 pm-2:13 pm

2 stops20h 43m

Medellín Jose Maria Cordova Intl

Mon 2/23

3:15 pm-11:12 pm

1 stop7h 57m

$426

WilmingtonBogotá

ILM - BOG

ILMBOG

Wilmington New Hanover County

Mon 2/2

6:00 am-7:30 pm

1 stop13h 30m

Bogotá El Dorado

Thu 2/5

9:00 am-11:51 pm

1 stop14h 51m

$493

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/29

2:25 pm-2:15 pm

2 stops23h 50m

Medellín Jose Maria Cordova Intl

Mon 2/2

1:00 pm-8:20 pm

1 stop7h 20m

$497

WilmingtonBogotá

ILM - BOG

ILMBOG

Wilmington New Hanover County

Sun 1/25

10:23 am-7:30 pm

1 stop9h 07m

Bogotá El Dorado

Sun 2/1

9:00 am-4:56 pm

1 stop7h 56m

$583

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 2/5

5:01 pm-1:55 pm

1 stop20h 54m

Medellín Jose Maria Cordova Intl

Mon 2/9

1:00 pm-8:20 pm

1 stop7h 20m

$589

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/15

2:25 pm-8:18 am

2 stops41h 53m

Medellín Jose Maria Cordova Intl

Mon 1/19

1:00 pm-8:20 pm

1 stop7h 20m

$591

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/29

6:00 am-9:10 pm

2 stops15h 10m

Medellín Jose Maria Cordova Intl

Mon 2/2

7:00 am-10:57 pm

2 stops15h 57m

$620

WilmingtonQuito

ILM - UIO

ILMUIO

Wilmington New Hanover County

Thu 3/12

6:00 am-10:23 pm

1 stop17h 23m

Quito Mariscal Sucr

Mon 3/23

6:30 am-7:12 pm

1 stop11h 42m

$626

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 1/8

6:00 am-2:03 pm

1 stop8h 03m

Medellín Jose Maria Cordova Intl

Mon 1/12

3:10 pm-11:57 pm

1 stop8h 47m

$637

WilmingtonMedellín

ILM - MDE

ILMMDE

Wilmington New Hanover County

Thu 2/5

6:30 am-9:10 pm

2 stops14h 40m

Medellín Jose Maria Cordova Intl

Mon 2/9

3:10 pm-10:42 am

2 stops19h 32m

$642

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 44 results

...

Best time to book a flight from Wilmington to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Wilmington with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to South America

What is the cheapest time of day to fly from ILM to SA?

It’s typically best to fly out from Wilmington to South America in the evening. Doing so could potentially save you 56% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with Delta and American Airlines from Wilmington to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,007 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,050 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

What airport do you fly from for flights from Wilmington to South America?
Wilmington New Hanover County (ILM), located 4.3 mi from the city center, is the airport you fly out of when you book flights from Wilmington to South America.
How long is the flight from Wilmington to South America?
For as low as $493, LATAM Airlines can have you in South America from Wilmington in 13h 30m. Wilmington and South America are separated by a distance of 2056 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from Wilmington to South America?
When deciding which route to take from Wilmington to South America consider Wilmington New Hanover County - Medellín Jose Maria Cordova Intl, Wilmington New Hanover County - Quito Mariscal Sucr or Wilmington New Hanover County - Santiago Arturo Merino Benitez as they are the most popular.
Can I find deals for flights from Wilmington to South America that include hotel bookings?
Yes. In addition to deals on Wilmington to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Wilmington to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to South America.
Can I find deals for business class flights from Wilmington to South America?
Yes. Cheapflights offers flight deals from Wilmington to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Wilmington to South America

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$454	Average$1,176	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$533	Average$722	FlexibilityNo cancel fee	On-time71%

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$162+ Cheap flights from Wilmington (ILM) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Wilmington to South America with Cheapflights

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Cheap flight deals from Wilmington to South America

Cheapest flights from Wilmington to South AmericaExplore the most affordable flight options available from Wilmington to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Wilmington to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Wilmington to South America

Keep the following information in mind while searching for Wilmington to South America flight deals. Data was last updated December 12, 2025.

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Wilmington to South America that are best for you.

Best time to book a flight from Wilmington to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Wilmington with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to South America

What is the cheapest time of day to fly from ILM to SA?

Find hourly flight availability from Wilmington to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with Delta and American Airlines from Wilmington to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Wilmington to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Wilmington to South America?

How long is the flight from Wilmington to South America?

What are the most popular routes from Wilmington to South America?

Can I find deals for flights from Wilmington to South America that include hotel bookings?

How can I find direct flights from Wilmington to South America?

Can I find deals for business class flights from Wilmington to South America?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Wilmington to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Wilmington to South America

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Cheapest flights from Wilmington to South America
Explore the most affordable flight options available from Wilmington to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.