$248+ Cheap flights from San Diego (SAN) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Oct 24 — Oct 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to South AmericaExplore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop20h 35m
Wed 11/255:20 pm -
1 stop20h 58m
Deal found 9/19![Multiple Airlines logo]()
$525
This eDestinos deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:55 am -
2 stops14h 00m
Sat 10/175:25 pm -
1 stop23h 10m
Deal found 9/21![Multiple Airlines logo]()
$539
This eDestinos deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:03 am -
1 stop27h 22m
Sun 11/87:00 am -
1 stop16h 45m
Deal found 9/19![Multiple Airlines logo]()
$543
This Avianca deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:00 am -
1 stop21h 35m
Tue 11/35:20 pm -
1 stop20h 08m
Deal found 9/20![Multiple Airlines logo]()
$556
This eDestinos deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:41 am -
1 stop22h 34m
Mon 11/911:05 pm -
1 stop24h 40m
Deal found 9/19![Multiple Airlines logo]()
$560
This eDestinos deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am -
1 stop27h 25m
Fri 10/234:50 pm -
1 stop23h 45m
Deal found 9/19![Multiple Airlines logo]()
$562
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:30 pm -
1 stop10h 25m
Wed 10/289:15 am -
1 stop11h 12m
Deal found 9/20![Copa Airlines logo]()
$575
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:20 pm -
1 stop13h 55m
Sat 11/711:05 pm -
1 stop14h 30m
Deal found 9/21![Multiple Airlines logo]()
$576
This FlightHub deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:15 am -
1 stop12h 35m
Mon 12/712:00 pm -
1 stop13h 56m
Deal found 9/21![LATAM Airlines logo]()
$580
This eDestinos deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:22 pm -
1 stop13h 53m
Tue 10/2011:15 pm -
1 stop17h 20m
Deal found 9/20![Multiple Airlines logo]()
$580
This Orbitz deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:22 pm -
2 stops25h 23m
Wed 11/45:20 pm -
1 stop20h 08m
Deal found 9/22![Multiple Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:49 am -
1 stop23h 23m
Tue 11/103:12 pm -
1 stop22h 37m
Deal found 9/19![American Airlines logo]()
$588
Best flights from San Diego to South AmericaDiscover carefully curated flight deals from San Diego to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from San Diego to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:00 am -
1 stop20h 35m
Wed 11/255:20 pm -
1 stop20h 58m
Deal found 9/21![Multiple Airlines logo]()
$525
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:30 pm -
1 stop9h 10m
Sun 10/256:20 pm -
1 stop26h 07m
Deal found 9/23![Copa Airlines logo]()
$576
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:49 am -
1 stop23h 23m
Tue 11/103:12 pm -
1 stop22h 37m
Deal found 9/19![American Airlines logo]()
$588
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:30 pm -
2 stops28h 40m
Sun 11/810:40 am -
1 stop13h 46m
Deal found 9/20![United Airlines logo]()
$592
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:45 pm -
1 stop21h 35m
Fri 10/3012:15 am -
2 stops21h 21m
Deal found 9/19![Delta logo]()
$665
This BusinessClass deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:08 pm -
2 stops21h 27m
Wed 10/281:35 pm -
2 stops21h 41m
Deal found 9/21![GOL logo]()
$667
This LATAM Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/56:15 am -
2 stops19h 05m
Fri 3/197:20 am -
2 stops19h 35m
Deal found 9/23![LATAM Airlines logo]()
$928
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:00 am -
1 stop20h 35m
Tue 11/105:20 pm -
1 stop20h 15m
Deal found 9/19![Multiple Airlines logo]()
$556
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:30 pm -
1 stop8h 15m
Sun 11/86:25 pm -
1 stop25h 50m
Deal found 9/21![Copa Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:01 pm -
2 stops27h 09m
Tue 12/810:40 am -
2 stops25h 30m
Deal found 9/19![United Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
2 stops15h 50m
Thu 11/122:35 pm -
1 stop12h 03m
Deal found 9/19![American Airlines logo]()
$644
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:30 pm -
1 stop23h 36m
Wed 10/284:45 am -
1 stop15h 42m
Deal found 9/21![Copa Airlines logo]()
$594
This oojo deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:22 pm -
2 stops31h 18m
Sat 10/175:25 pm -
1 stop23h 10m
Deal found 9/19![Multiple Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:46 pm -
1 stop26h 24m
Sun 10/259:45 am -
2 stops26h 27m
Deal found 9/23![United Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:25 pm -
2 stops20h 25m
Thu 11/1912:10 pm -
1 stop14h 22m
Deal found 9/21![Delta logo]()
$665
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:30 pm -
1 stop10h 36m
Thu 10/2910:40 am -
1 stop9h 47m
Deal found 9/22![Copa Airlines logo]()
$594
This FlightHub deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:20 pm -
2 stops29h 40m
Wed 1/205:20 pm -
1 stop22h 38m
Deal found 9/19![Multiple Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:05 am -
1 stop11h 30m
Sun 11/151:30 am -
1 stop19h 23m
Deal found 9/22![United Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:07 pm -
2 stops19h 28m
Tue 10/271:35 pm -
2 stops21h 41m
Deal found 9/20![American Airlines logo]()
$669
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
2 stops19h 05m
Mon 12/78:20 am -
2 stops18h 18m
Deal found 9/22![Delta logo]()
$670
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:30 pm -
1 stop12h 59m
Thu 10/2910:40 am -
1 stop9h 47m
Deal found 9/22![Copa Airlines logo]()
$594
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:15 am -
2 stops19h 45m
Tue 12/812:50 am -
1 stop12h 35m
Deal found 9/19![Delta logo]()
$670
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:20 am -
2 stops13h 15m
Mon 11/231:30 am -
2 stops18h 45m
Deal found 9/23![United Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:49 am -
1 stop24h 47m
Wed 12/92:35 pm -
1 stop12h 03m
Deal found 9/23![American Airlines logo]()
$678
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:30 pm -
1 stop9h 40m
Wed 10/216:10 am -
1 stop14h 20m
Deal found 9/23![Copa Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:00 am -
2 stops15h 54m
Thu 10/298:15 am -
1 stop11h 38m
Deal found 9/22![United Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:25 pm -
2 stops15h 11m
Sun 12/208:00 am -
1 stop18h 59m
Deal found 9/22![American Airlines logo]()
$698
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:30 pm -
1 stop22h 25m
Wed 11/187:00 am -
1 stop13h 15m
Deal found 9/21![Copa Airlines logo]()
$594
This oojo deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:39 pm -
1 stop28h 11m
Wed 1/138:35 pm -
2 stops19h 23m
Deal found 9/21![Multiple Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:00 pm -
1 stop9h 10m
Mon 11/98:15 am -
2 stops15h 09m
Deal found 9/23![United Airlines logo]()
$617
Last-minute flights from San Diego to South AmericaDiscover last-minute flight deals from San Diego to South America. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South America. Data last updated September 24, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:20 pm -
1 stop13h 55m
Sat 11/711:05 pm -
1 stop14h 30m
Deal found 9/21![Multiple Airlines logo]()
$576
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:30 pm -
1 stop13h 45m
Fri 10/165:00 am -
1 stop15h 30m
Deal found 9/21![Copa Airlines logo]()
$576
This Avianca deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:55 am -
2 stops14h 00m
Thu 10/84:05 am -
2 stops15h 05m
Deal found 9/23![Multiple Airlines logo]()
$595
This Aviatur deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
1 stop21h 15m
Fri 10/92:00 pm -
1 stop32h 36m
Deal found 9/21![Multiple Airlines logo]()
$605
This eDestinos deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:55 am -
2 stops14h 00m
Sat 10/175:25 pm -
1 stop23h 10m
Deal found 9/21![Multiple Airlines logo]()
$539
This eDestinos deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:22 pm -
1 stop13h 53m
Tue 10/2011:15 pm -
1 stop17h 20m
Deal found 9/20![Multiple Airlines logo]()
$580
This eDestinos deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am -
1 stop27h 25m
Fri 10/234:50 pm -
1 stop23h 45m
Deal found 9/19![Multiple Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:24 pm -
2 stops13h 30m
Thu 10/228:30 am -
2 stops29h 05m
Deal found 9/22![United Airlines logo]()
$611
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:30 pm -
1 stop12h 59m
Thu 10/2910:40 am -
1 stop9h 47m
Deal found 9/22![Copa Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:00 pm -
1 stop11h 54m
Thu 10/298:15 am -
1 stop11h 38m
Deal found 9/22![United Airlines logo]()
$606
This Avianca deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:00 am -
1 stop21h 35m
Tue 11/35:20 pm -
1 stop20h 08m
Deal found 9/20![Multiple Airlines logo]()
$556
This Orbitz deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:22 pm -
2 stops25h 23m
Wed 11/45:20 pm -
1 stop20h 08m
Deal found 9/22![Multiple Airlines logo]()
$586
One-way flights from San Diego to South AmericaSearch for one-way flight options from San Diego to South America. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from San Diego to South America. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Avianca deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/167:00 am -
1 stop20h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$248
This eDestinos deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:09 am -
1 stop22h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:22 pm -
2 stops39h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$266
This oojo deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:22 pm -
2 stops20h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/253:30 pm -
3 stops42h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$269
This Viajes Falabella deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Falabella is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop21h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:30 pm -
1 stop10h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Copa Airlines logo]()
$283
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:30 pm -
1 stop13h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Copa Airlines logo]()
$284
This Orbitz deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:00 pm -
2 stops26h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/238:00 am -
1 stop11h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$287
This FlightHub deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:15 am -
2 stops22h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Aeromexico logo]()
$292
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:56 pm -
3 stops27h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$293
Find flight deals from San Diego to South America
Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated September 24, 2026.
Round-trip from | $517 (Avianca) |
|---|---|
One-way from | $248 (Avianca) |
Popular in | January |
Cheapest in | November |
Average price | $570 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from San Diego to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoQuito
SAN San Diego - UIO Quito Mariscal Sucr
SANUIO
San Diego
Sat 1/16
7:00 am-6:35 am
1 stop20h 35m
Quito Mariscal Sucr
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$248
San DiegoQuito
SAN San Diego - UIO Quito Mariscal Sucr
SANUIO
San Diego
Thu 10/8
2:22 pm-1:05 pm
2 stops20h 43m
Quito Mariscal Sucr
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$269
Quickest round-trip
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Mon 10/5
10:30 pm-10:55 am
1 stop10h 25m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$283
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Fri 10/2
10:30 pm-2:15 pm
1 stop13h 45m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Mon 11/30
10:30 pm-2:15 pm
1 stop12h 45m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 2/3
7:41 pm-10:10 pm
2 stops23h 29m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$287
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Fri 1/22
7:41 pm-10:10 pm
2 stops23h 29m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$287
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Sun 1/31
8:00 am-10:10 pm
1 stop11h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$287
San DiegoBogotá
SAN San Diego - BOG Bogotá El Dorado
SANBOG
San Diego
Sun 10/25
6:15 am-6:40 am
2 stops22h 25m
Bogotá El Dorado
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$292
San DiegoBogotá
SAN San Diego - BOG Bogotá El Dorado
SANBOG
San Diego
Tue 12/1
4:58 pm-11:51 am
2 stops39h 53m
Bogotá El Dorado
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$299
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
SAN-UIO
SAN-BOG
SAN-MDE
SAN-LIM
SAN-CTG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South America
SAN-0SA
SAN-UIO
SAN-BOG
SAN-MDE
SAN-LIM
What is the cheapest month to book a flight from San Diego to South America?
Currently, February is the cheapest month in which you can book a flight from San Diego to South America (average of $651). Flying from San Diego to South America in December is currently the most expensive (average of $1,161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from San Diego to South America?
The best time to book flights from San Diego to South America is 3 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 24, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for San Diego to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to South America by cabin class
Find flights from San Diego to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South America flights
Browse other San Diego and South America flight options. Last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
San Diego to South America flights
Consider these flights traveling from San Diego to South America.
Top 7 airlines flying from San Diego to South America
Discover the top 7 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$893 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$332 | Average$627 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$352 | Average$1,034 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$437 | Average$903 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$464 | Average$754 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$516 | Average$783 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$695 | Average$1,423 | FlexibilityNo cancel fee | On-time74% |