South America

$163+ Cheap flights from San Diego (SAN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
kwi 26 — maj 31
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Cheap flight deals from San Diego to South America

Cheapest flights from San Diego to South America
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Marzec 27, 2026.

This Copa Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/1310:00 pm
SAN
-
UIO
1 stop12h 32m
Copa Airlines
ndz. 5/246:00 am
UIO
-
SAN
1 stop14h 30m
Copa Airlines
Deal found 3/26$401
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/283:10 pm
SAN
-
UIO
1 stop11h 50m
United Airlines
pt. 6/512:35 am
UIO
-
SAN
1 stop19h 06m
United Airlines
Deal found 3/22$413
This Avianca deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 10/168:40 pm
SAN
-
BOG
1 stop13h 45m
Multiple Airlines
ndz. 10/257:05 am
BOG
-
SAN
1 stop13h 54m
Multiple Airlines
Deal found 3/25$421
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 5/303:10 pm
SAN
-
UIO
1 stop30h 15m
United Airlines
pt. 6/57:25 am
UIO
-
SAN
1 stop12h 16m
United Airlines
Deal found 3/22$422
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/810:00 pm
SAN
-
UIO
1 stop14h 10m
Copa Airlines
czw. 5/143:07 am
UIO
-
SAN
1 stop17h 23m
Copa Airlines
Deal found 3/24$426
This Copa Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/2710:00 pm
SAN
-
UIO
1 stop17h 32m
Copa Airlines
ndz. 6/78:21 am
UIO
-
SAN
1 stop12h 19m
Copa Airlines
Deal found 3/25$431
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/274:07 pm
SAN
-
UIO
2 stops34h 53m
United Airlines
pt. 6/512:35 am
UIO
-
SAN
1 stop19h 06m
United Airlines
Deal found 3/22$432
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/1310:00 pm
SAN
-
UIO
1 stop24h 34m
Copa Airlines
wt. 5/193:09 pm
UIO
-
SAN
1 stop29h 21m
Copa Airlines
Deal found 3/25$440
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 9/285:00 pm
SAN
-
UIO
2 stops28h 25m
United Airlines
śr. 9/3012:35 am
UIO
-
SAN
1 stop23h 18m
United Airlines
Deal found 3/25$447
This eDestinos deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/149:37 pm
SAN
-
BOG
1 stop20h 53m
Multiple Airlines
pon. 5/1811:15 pm
BOG
-
SAN
1 stop17h 23m
Multiple Airlines
Deal found 3/22$447
This Trip.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 10/219:56 pm
SAN
-
MDE
1 stop33h 14m
Multiple Airlines
pt. 11/611:00 pm
MDE
-
SAN
1 stop22h 59m
Multiple Airlines
Deal found 3/22$451
This oojo deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/46:52 am
SAN
-
BOG
1 stop21h 23m
Multiple Airlines
pon. 5/114:50 pm
BOG
-
SAN
1 stop21h 58m
Multiple Airlines
Deal found 3/23$451

Find flight deals from San Diego to South America

Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated Marzec 27, 2026.

Round-trip from

$401
(Copa Airlines)

One-way from

$163
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$685
From San Diego to South America
One-way flight from San Diego to South America
Highest demand for flights based on searches. 11% potential increase in price ($71 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Marzec 27, 2026.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoQuito

SAN - UIO

SANUIO

San Diego

śr. 5/13

10:00 pm-12:32 pm

1 stop12h 32m

Quito Mariscal Sucr

ndz. 5/24

8:27 am-6:30 pm

1 stop12h 03m

$401

San DiegoQuito

SAN - UIO

SANUIO

San Diego

czw. 5/28

5:15 pm-5:00 am

1 stop9h 45m

Quito Mariscal Sucr

sob. 6/6

7:25 am-11:54 pm

2 stops18h 29m

$418

San DiegoQuito

SAN - UIO

SANUIO

San Diego

śr. 5/27

4:07 pm-5:00 am

2 stops34h 53m

Quito Mariscal Sucr

pt. 6/5

12:35 am-5:41 pm

1 stop19h 06m

$432

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

ndz. 4/19

9:18 pm-5:26 pm

1 stop18h 08m

Bogotá El Dorado

ndz. 4/26

8:35 am-6:30 pm

1 stop11h 55m

$453

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

pt. 5/8

10:00 pm-11:06 am

1 stop11h 06m

Bogotá El Dorado

pon. 5/18

9:45 am-6:30 pm

1 stop10h 45m

$453

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

śr. 6/17

10:00 pm-5:26 pm

1 stop17h 26m

Bogotá El Dorado

czw. 7/9

4:59 am-6:30 pm

1 stop15h 31m

$453

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

pt. 5/15

10:00 pm-10:10 am

1 stop10h 10m

Bogotá El Dorado

pt. 5/22

6:10 am-6:30 pm

1 stop14h 20m

$453

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

pt. 4/17

10:30 pm-1:40 pm

1 stop13h 10m

Bogotá El Dorado

śr. 4/22

9:00 am-11:25 pm

1 stop16h 25m

$465

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

sob. 4/18

6:20 am-7:20 pm

2 stops11h 00m

Bogotá El Dorado

pt. 4/24

12:14 am-1:51 pm

1 stop15h 37m

$465

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

pon. 5/4

10:23 am-4:54 am

1 stop16h 31m

Bogotá El Dorado

śr. 5/6

8:30 am-9:25 pm

1 stop14h 55m

$465

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from San Diego to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South America

What is the cheapest month to book a flight from San Diego to South America?

Currently, April is the cheapest month in which you can book a flight from San Diego to South America (average of $177). Flying from San Diego to South America in May is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated Marzec 27, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to South America?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to South America from San Diego.

  • How long is the flight from San Diego to South America?

    Airlines like Copa Airlines, United Airlines, and Delta fly from San Diego to South America in about 12h 32m. The time it takes to get you to your destination can typically vary by up to 22h 21m. Airlines will cover a distance of 3394 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to South America one-way?

    The cheapest airlines for a one-way flight from San Diego to South America are United Airlines ($163), Copa Airlines ($168), and American Airlines ($208).

  • What are the most popular routes from San Diego to South America?

  • Can I find deals for flights from San Diego to South America that include hotel bookings?

    Yes. In addition to deals on San Diego to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South America.

  • Can I find deals for business class flights from San Diego to South America?

    Yes. Cheapflights offers flight deals from San Diego to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South America?

    Currently, April is the cheapest month in which you can book a flight from San Diego to South America (average of $177). Flying from San Diego to South America in May is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from San Diego to South America

Discover the top 7 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Marzec 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$305Average$623FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$334Average$884FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$335Average$771FlexibilityNo cancel feeOn-time81%
DeltaCheapest$430Average$991FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$452Average$880FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$620Average$783FlexibilityNo cancel feeOn-time67%
GOLCheapest$645Average$1,087FlexibilityNo cancel feeOn-time74%

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