South America

$142+ Cheap flights from San Diego (SAN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
May 5 — May 121
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Diego to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Diego to South America

Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated April 30, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$353
(Copa Airlines)

One-way from

$142
(eDestinos)

Popular in

December

Cheapest in

February

Average price

$884
Provider with most accurate pricing for San Diego-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for San Diego-Sao Paulo (SAO) flights.
From San Diego to South America
One-way flight from San Diego to South America
Highest demand for flights based on searches. 9% potential increase in price ($104 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from San Diego to South America

Cheapest flights from San Diego to South America
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/258:58 pmSAN - BOG
1 stop18h 28mCopa Airlines
Sun 8/104:54 amBOG - SAN
1 stop14h 50mCopa Airlines
Deal found 4/28$353
This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/279:06 pmSAN - MDE
1 stop11h 23mCopa Airlines
Sun 7/65:07 amMDE - SAN
1 stop14h 37mCopa Airlines
Deal found 4/28$359
This FlightHub deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:43 pmSAN - BOG
2 stops17h 22mSpirit Airlines
Sat 5/172:07 pmBOG - SAN
2 stops19h 06mSpirit Airlines
Deal found 4/28$394
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/79:03 pmSAN - LIM
1 stop16h 37mCopa Airlines
Sat 9/202:35 amLIM - SAN
1 stop17h 15mCopa Airlines
Deal found 4/29$453
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:15 amSAN - MDE
2 stops29h 00mSpirit Airlines
Sat 6/72:13 pmMDE - SAN
2 stops19h 00mSpirit Airlines
Deal found 4/29$460
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/266:58 pmSAN - BOG
3 stops24h 31mMultiple Airlines
Mon 6/22:07 pmBOG - SAN
2 stops19h 06mMultiple Airlines
Deal found 4/27$492
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/299:45 pmSAN - BOG
1 stop19h 30mDelta
Thu 6/59:00 amBOG - SAN
1 stop16h 42mDelta
Deal found 4/28$513
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:43 pmSAN - MDE
3 stops26h 50mMultiple Airlines
Mon 5/264:20 amMDE - SAN
3 stops28h 53mMultiple Airlines
Deal found 4/29$514
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/87:15 amSAN - BOG
1 stop13h 15mAmerican Airlines
Tue 6/246:30 amBOG - SAN
2 stops14h 59mAmerican Airlines
Deal found 4/29$518
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:15 amSAN - BOG
1 stop11h 05mUnited Airlines
Sun 6/112:14 amBOG - SAN
1 stop19h 23mUnited Airlines
Deal found 4/28$523
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/43:25 pmSAN - MDE
1 stop11h 17mUnited Airlines
Tue 6/1012:15 amMDE - SAN
1 stop11h 02mUnited Airlines
Deal found 4/29$533
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/13:35 pmSAN - BOG
1 stop20h 05mLATAM Airlines
Sat 6/79:00 amBOG - SAN
1 stop16h 42mLATAM Airlines
Deal found 4/28$546

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

San Diego

Fly to

South America

Route

Depart

Return

Price

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Fri 7/25

8:58 pm-5:26 pm

1 stop18h 28m

Bogotá El Dorado

Sun 8/10

4:54 am-5:44 pm

1 stop14h 50m

$353

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Fri 6/27

9:06 pm-10:29 am

1 stop11h 23m

Medellín Jose Maria Cordova Intl

Sun 7/6

5:07 am-5:44 pm

1 stop14h 37m

$359

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Sat 5/10

5:43 pm-1:05 pm

2 stops17h 22m

Bogotá El Dorado

Sat 5/17

2:07 pm-7:13 am

2 stops19h 06m

$394

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sun 5/25

6:15 am-1:15 pm

2 stops29h 00m

Medellín Jose Maria Cordova Intl

Sat 6/7

2:13 pm-7:13 am

2 stops19h 00m

$460

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Mon 5/26

6:58 pm-9:29 pm

3 stops24h 31m

Bogotá El Dorado

Mon 6/2

2:07 pm-7:13 am

2 stops19h 06m

$492

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Thu 5/29

3:35 pm-1:40 pm

1 stop20h 05m

Bogotá El Dorado

Fri 6/6

9:00 am-6:02 pm

1 stop11h 02m

$513

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Thu 5/22

5:43 pm-10:33 pm

3 stops26h 50m

Medellín Jose Maria Cordova Intl

Mon 5/26

4:20 am-7:13 am

3 stops28h 53m

$514

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Sun 6/8

7:15 am-10:30 pm

1 stop13h 15m

Bogotá El Dorado

Tue 6/24

6:30 am-7:29 pm

2 stops14h 59m

$518

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Fri 5/30

6:15 am-7:20 pm

1 stop11h 05m

Bogotá El Dorado

Mon 6/2

8:30 am-9:20 pm

1 stop14h 50m

$523

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Wed 6/4

3:25 pm-4:42 am

1 stop11h 17m

Medellín Jose Maria Cordova Intl

Tue 6/10

12:15 am-9:17 am

1 stop11h 02m

$533

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from San Diego to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South America

What is the cheapest month to book a flight from San Diego to South America?

Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SA?

Find hourly flight availability from San Diego to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from San Diego to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 30, 2025.

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
8.0
Very good

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to South America?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to South America from San Diego.

  • What are the cheapest airlines to fly from San Diego to South America one-way?

    The cheapest airlines for a one-way flight from San Diego to South America are Spirit Airlines ($142), American Airlines ($233), and LATAM Airlines ($236).

  • What are the most popular routes from San Diego to South America?

  • Can I find deals for flights from San Diego to South America that include hotel bookings?

    Yes. In addition to deals on San Diego to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South America.

  • Can I find deals for business class flights from San Diego to South America?

    Yes. Cheapflights offers flight deals from San Diego to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South America?

    Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from San Diego to South America

Discover the top 8 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$286Average$440FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$400Average$923FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$402Average$818FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$449Average$912FlexibilityNo cancel feeOn-time81%
DeltaCheapest$449Average$1,025FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$1,028FlexibilityNo cancel feeOn-time71%
GOLCheapest$819Average$1,037FlexibilityNo cancel feeOn-time74%
Air CanadaCheapest$985Average$1,084FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.