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South America

$149+ Cheap flights from San Diego (SAN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from San Diego to South America

Cheapest flights from San Diego to South America
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:45 pmSAN - BOG
1 stop18h 45mDelta
Mon 1/263:55 pmBOG - SAN
1 stop21h 03mDelta
Deal found 12/10$473
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:15 pmSAN - BOG
2 stops24h 15mLATAM Airlines
Mon 1/263:55 pmBOG - SAN
2 stops24h 38mLATAM Airlines
Deal found 12/10$545
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:11 amSAN - MDE
2 stops15h 31mUnited Airlines
Wed 12/171:15 amMDE - SAN
3 stops22h 33mUnited Airlines
Deal found 12/10$548
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:12 pmSAN - BOG
1 stop10h 13mCopa Airlines
Tue 12/164:45 amBOG - SAN
1 stop15h 52mCopa Airlines
Deal found 12/10$559
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:12 pmSAN - CTG
1 stop14h 53mCopa Airlines
Wed 12/179:42 amCTG - SAN
1 stop10h 55mCopa Airlines
Deal found 12/11$562
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:59 amSAN - MDE
3 stops50h 56mMultiple Airlines
Sat 12/2010:15 pmMDE - SAN
2 stops25h 56mMultiple Airlines
Deal found 12/10$575
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:40 pmSAN - BOG
2 stops22h 55mUnited Airlines
Sat 12/131:30 amBOG - SAN
1 stop19h 51mUnited Airlines
Deal found 12/10$576
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:10 pmSAN - BOG
1 stop9h 00mUnited Airlines
Wed 1/148:15 amBOG - SAN
2 stops18h 27mUnited Airlines
Deal found 12/11$592
This KAYAK deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:15 amSAN - GRU
1 stop18h 25mLATAM Airlines
Sun 12/2810:40 amGRU - SAN
1 stop17h 48mLATAM Airlines
Deal found 12/9$600
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:59 amSAN - MDE
3 stops50h 56mMultiple Airlines
Fri 12/1910:45 pmMDE - SAN
2 stops49h 26mMultiple Airlines
Deal found 12/10$607
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:10 pmSAN - MDE
1 stop25h 55mUnited Airlines
Tue 12/301:15 amMDE - SAN
2 stops22h 32mUnited Airlines
Deal found 12/10$619
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:25 pmSAN - BOG
2 stops17h 15mAmerican Airlines
Wed 12/178:00 amBOG - SAN
1 stop18h 00mAmerican Airlines
Deal found 12/10$632

Find flight deals from San Diego to South America

Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated December 12, 2025.

Round-trip from

$353
(Trip.com)

One-way from

$149
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$619
From San Diego to South America
Search Deals
One-way flight from San Diego to South America
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

San Diego

Fly to

South America

Route

Depart

Return

Price

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Mon 2/16

7:35 am-6:15 am

1 stop19h 40m

Bogotá El Dorado

Wed 3/4

11:15 pm-7:35 pm

1 stop23h 20m

$353

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Fri 1/16

8:16 pm-9:25 am

1 stop10h 09m

Bogotá El Dorado

Fri 1/23

8:40 am-5:41 pm

1 stop12h 01m

$461

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Fri 4/24

9:15 am-1:20 pm

2 stops26h 05m

Bogotá El Dorado

Tue 4/28

3:59 am-8:29 pm

2 stops18h 30m

$464

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Fri 1/23

10:30 pm-2:25 pm

1 stop12h 55m

Bogotá El Dorado

Tue 1/27

6:35 pm-9:58 am

2 stops18h 23m

$473

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Thu 4/16

9:15 am-1:53 pm

2 stops26h 38m

Medellín Jose Maria Cordova Intl

Fri 5/15

3:15 am-8:38 pm

2 stops19h 23m

$479

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Sat 1/31

7:51 am-10:05 am

2 stops23h 14m

Cartagena Rafael Nunez

Sat 2/7

9:25 pm-7:46 pm

2 stops25h 21m

$488

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Wed 1/28

8:16 pm-2:45 pm

1 stop15h 29m

Medellín Jose Maria Cordova Intl

Mon 2/16

9:17 am-5:13 pm

1 stop10h 56m

$501

San DiegoLima

SAN - LIM

SANLIM

San Diego

Fri 1/23

8:16 pm-7:15 pm

1 stop19h 59m

Lima J Chavez Intl

Fri 1/30

7:00 am-5:41 pm

1 stop13h 41m

$502

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Wed 1/28

7:51 am-1:10 pm

3 stops50h 19m

Cartagena Rafael Nunez

Wed 2/4

9:55 pm-7:46 pm

2 stops24h 51m

$502

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Wed 1/28

8:16 pm-2:04 pm

1 stop14h 48m

Cartagena Rafael Nunez

Wed 2/4

6:25 am-5:13 pm

1 stop13h 48m

$504

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South America

What is the cheapest month to book a flight from San Diego to South America?

Currently, August is the cheapest month in which you can book a flight from San Diego to South America (average of $201). Flying from San Diego to South America in June is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SA?

Find hourly flight availability from San Diego to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from San Diego to South America in the afternoon. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from San Diego to South America?

Use this chart to determine the cheapest time to fly round-trip from San Diego to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Diego to South America flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,558 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,887 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to South America?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to South America from San Diego.

  • How long is the flight from San Diego to South America?

    Airlines like Copa Airlines, Delta, and United Airlines fly from San Diego to South America in about 10h 09m. The time it takes to get you to your destination can typically vary by up to 9h 06m. Airlines will cover a distance of 3378 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to South America one-way?

    The cheapest airlines for a one-way flight from San Diego to South America are Copa Airlines ($169), United Airlines ($202), and American Airlines ($217).

  • What are the most popular routes from San Diego to South America?

    The most popular route from San Diego to South America is San Diego - Rio de Janeiro–Galeão Intl. You may also consider San Diego - Medellín Jose Maria Cordova Intl or San Diego - Lima J Chavez Intl.

  • Can I find deals for flights from San Diego to South America that include hotel bookings?

    Yes. In addition to deals on San Diego to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South America.

  • Can I find deals for business class flights from San Diego to South America?

    Yes. Cheapflights offers flight deals from San Diego to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South America?

    Currently, August is the cheapest month in which you can book a flight from San Diego to South America (average of $201). Flying from San Diego to South America in June is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from San Diego to South America

Discover the top 6 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$342Average$613FlexibilityNo cancel feeOn-time70%
DeltaCheapest$430Average$1,002FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$443Average$944FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$452Average$833FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$460Average$907FlexibilityNo cancel feeOn-time71%
GOLCheapest$645Average$991FlexibilityNo cancel feeOn-time74%

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