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South America

$106+ Cheap flights from Raleigh (RDU) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Dec 31 — Jan 71
Wed 12/31
Wed 1/7
1 adult, Economy
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Cheap flight deals from Raleigh to South America

Keep the following information in mind while searching for Raleigh to South America flight deals. Data was last updated December 1, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$256
(Copa Airlines)

One-way from

$106
(Copa Airlines)

Popular in

January

Cheapest in

August

Average price

$774
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
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From Raleigh-Durham to South America
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One-way flight from Raleigh-Durham to South America
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Highest demand for flights based on searches. 16% potential increase in price ($124 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Find flight deals from Raleigh to South America

Cheapest flights from Raleigh to South America
Explore the most affordable flight options available from Raleigh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 1, 2025.

This United Airlines deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:20 amRDU - MDE
2 stops23h 22mUnited Airlines
Sat 12/1310:45 amMDE - RDU
1 stop11h 30mUnited Airlines
Deal found 11/29$308
This United Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:30 amRDU - MDE
1 stop15h 35mUnited Airlines
Fri 12/121:15 amMDE - RDU
1 stop14h 29mUnited Airlines
Deal found 11/28$328
This JetBlue deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:15 amRDU - MDE
1 stop7h 22mJetBlue
Sun 12/72:04 pmMDE - RDU
1 stop8h 13mJetBlue
Deal found 12/1$333
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:48 pmRDU - MDE
1 stop29h 17mUnited Airlines
Mon 12/81:15 amMDE - RDU
1 stop11h 29mUnited Airlines
Deal found 12/1$337
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:48 pmRDU - MDE
1 stop29h 17mUnited Airlines
Wed 12/1010:45 amMDE - RDU
2 stops23h 29mUnited Airlines
Deal found 12/1$341
This eDestinos deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:50 pmRDU - MDE
1 stop7h 19mSpirit Airlines
Mon 12/222:25 amMDE - RDU
1 stop14h 30mSpirit Airlines
Deal found 11/30$343
This Copa Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:11 pmRDU - BOG
1 stop18h 14mCopa Airlines
Sun 12/144:45 amBOG - RDU
1 stop8h 40mCopa Airlines
Deal found 12/1$355
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:11 pmRDU - MDE
1 stop17h 07mMultiple Airlines
Wed 12/102:54 pmMDE - RDU
1 stop19h 37mMultiple Airlines
Deal found 11/30$358
This Copa Airlines deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:11 pmRDU - MDE
1 stop17h 07mCopa Airlines
Wed 12/106:24 amMDE - RDU
1 stop7h 01mCopa Airlines
Deal found 11/30$366
This Cheapflightsfares deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:50 pmRDU - MDE
1 stop7h 19mSpirit Airlines
Sun 12/142:05 amMDE - RDU
1 stop14h 50mSpirit Airlines
Deal found 11/30$372
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:11 pmRDU - MDE
1 stop17h 07mMultiple Airlines
Sat 12/133:10 pmMDE - RDU
1 stop25h 45mMultiple Airlines
Deal found 11/29$380
This United Airlines deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:30 amRDU - BOG
1 stop16h 05mUnited Airlines
Mon 12/88:15 amBOG - RDU
1 stop14h 00mUnited Airlines
Deal found 11/30$393

Cheapflights Fare Finder

 
Customize your flight search to find flights from Raleigh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
Use the filters below to find and compare flights from Raleigh to South America that are best for you.

Fly from

Raleigh

Fly to

South America

Route

Depart

Return

Price

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Fri 5/22

4:19 pm-8:40 am

1 stop17h 21m

Cartagena Rafael Nunez

Wed 5/27

6:24 am-2:29 pm

1 stop7h 05m

$256

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 1/11

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

Fri 1/30

6:26 am-1:15 pm

1 stop6h 49m

$285

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 2/9

7:35 pm-3:30 pm

2 stops19h 55m

Cartagena Rafael Nunez

Thu 2/12

2:35 pm-11:59 pm

1 stop9h 24m

$291

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 1/31

7:27 pm-3:30 pm

2 stops20h 03m

Cartagena Rafael Nunez

Wed 2/4

4:30 pm-11:59 pm

1 stop7h 29m

$291

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 2/5

5:14 pm-1:30 pm

2 stops20h 16m

Cartagena Rafael Nunez

Mon 2/9

4:30 pm-12:17 pm

2 stops19h 47m

$291

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Tue 1/20

7:35 pm-3:30 pm

2 stops19h 55m

Cartagena Rafael Nunez

Thu 1/29

2:30 pm-9:39 pm

1 stop7h 09m

$291

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 2/1

6:45 am-2:55 pm

1 stop8h 10m

Medellín Jose Maria Cordova Intl

Fri 2/6

2:25 pm-10:59 pm

1 stop8h 34m

$297

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 1/24

7:54 pm-3:30 pm

1 stop19h 36m

Cartagena Rafael Nunez

Sat 1/31

4:30 pm-11:33 am

2 stops19h 03m

$298

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sat 2/7

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Wed 2/11

10:45 am-10:30 pm

1 stop11h 45m

$303

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 2/1

3:12 pm-8:18 am

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Sun 2/15

6:25 am-1:14 pm

1 stop6h 49m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/30

Showing 1-10 of 60 results
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Best time to book a flight from Raleigh to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Raleigh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Raleigh to South America

What is the cheapest month to book a flight from Raleigh to South America?

Currently, March is the cheapest month in which you can book a flight from Raleigh to South America (average of $154). Flying from Raleigh to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RDU to SA?

Find hourly flight availability from Raleigh to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 1, 2025.

A simple way to save on the total cost of your ticket is to fly from Raleigh to South America in the afternoon. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Raleigh to South America?

Use this chart to determine the cheapest time to fly round-trip from Raleigh to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Raleigh to South America flight should consider departing on Tuesday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 1, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Raleigh to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,559 reviews
Delta
7.9
Good
8,010 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,890 reviews
Delta
7.9
Good
8,010 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,057 reviews
Delta
7.9
Good
8,010 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,010 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Raleigh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Raleigh to South America?

    Raleigh-Durham (RDU) is the airport you will fly out of if you book a flight from Raleigh to South America. It is only a 11.1 mi journey to Raleigh-Durham (RDU) from Raleigh’s city center.

  • How long is the flight from Raleigh to South America?

    Copa Airlines, American Airlines, and JetBlue can get you from Raleigh to South America in just under 8h 10m. Your travel time can differ by up to 11h 45m. There are 2063 mi between Raleigh and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Raleigh to South America one-way?

    For one-way options, check prices for Copa Airlines. According to our data, you can fly for as low as $106. Users have also found prices from $132 and $149 on United Airlines and Delta, respectively.

  • What are the most popular routes from Raleigh to South America?

    The most popular route from Raleigh to South America is Raleigh-Durham - Medellín Jose Maria Cordova Intl. You may also consider Raleigh-Durham - Bogotá El Dorado or Raleigh-Durham - Lima J Chavez Intl.

  • Can I find deals for flights from Raleigh to South America that include hotel bookings?

    Yes. In addition to deals on Raleigh to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Raleigh to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Raleigh to South America.

  • Can I find deals for business class flights from Raleigh to South America?

    Yes. Cheapflights offers flight deals from Raleigh to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Raleigh to South America?

    Currently, March is the cheapest month in which you can book a flight from Raleigh to South America (average of $154). Flying from Raleigh to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Raleigh to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Raleigh to South America

Discover the top 8 airlines that operate flights from Raleigh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$681FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$225Average$608FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$245Average$646FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$261Average$628FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$283Average$728FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$297Average$452FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$314Average$627FlexibilityNo cancel feeOn-time69%
GOLCheapest$540Average$1,211FlexibilityNo cancel feeOn-time74%

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