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South America

$115+ Cheap flights from Raleigh (RDU) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Feb 15 — Feb 221
Sun 2/15
Sun 2/22
1 adult, Economy
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Cheap flight deals from Raleigh to South America

Keep the following information in mind while searching for Raleigh to South America flight deals. Data was last updated January 16, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$252
(Copa Airlines)

One-way from

$115
(American Airlines)

Popular in

December

Cheapest in

November

Average price

$568
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
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From Raleigh-Durham to South America
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One-way flight from Raleigh-Durham to South America
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Highest demand for flights based on searches. 2% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Raleigh to South America

Cheapest flights from Raleigh to South America
Explore the most affordable flight options available from Raleigh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:14 pm
RDU
-
MDE
1 stop17h 04m
Copa Airlines
Mon 3/236:25 am
MDE
-
RDU
1 stop6h 58m
Copa Airlines
Deal found 1/14$252
This Copa Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/63:12 pm
RDU
-
CTG
1 stop17h 29m
Copa Airlines
Wed 2/116:25 am
CTG
-
RDU
1 stop6h 49m
Copa Airlines
Deal found 1/14$259
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/23:12 pm
RDU
-
MDE
1 stop23h 03m
Copa Airlines
Fri 2/65:00 am
MDE
-
RDU
1 stop8h 14m
Copa Airlines
Deal found 1/14$269
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/263:09 pm
RDU
-
MDE
1 stop19h 47m
Copa Airlines
Sat 1/319:17 am
MDE
-
RDU
1 stop27h 57m
Copa Airlines
Deal found 1/15$286
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:05 am
RDU
-
MDE
2 stops16h 10m
American Airlines
Thu 4/161:53 pm
MDE
-
RDU
2 stops17h 13m
American Airlines
Deal found 1/15$289
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/13:14 pm
RDU
-
CTG
1 stop16h 52m
Copa Airlines
Sun 3/89:42 am
CTG
-
RDU
1 stop27h 41m
Copa Airlines
Deal found 1/15$291
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:35 pm
RDU
-
CTG
2 stops19h 55m
American Airlines
Sun 2/84:30 pm
CTG
-
RDU
2 stops19h 03m
American Airlines
Deal found 1/14$294
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:10 am
RDU
-
BOG
1 stop18h 20m
American Airlines
Mon 2/93:15 pm
BOG
-
RDU
1 stop19h 46m
American Airlines
Deal found 1/15$294
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:15 am
RDU
-
BOG
1 stop16h 20m
United Airlines
Tue 2/108:15 am
BOG
-
RDU
1 stop14h 15m
United Airlines
Deal found 1/15$295
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:18 am
RDU
-
BOG
1 stop16h 17m
United Airlines
Mon 3/168:15 am
BOG
-
RDU
2 stops24h 19m
United Airlines
Deal found 1/16$296
This JetBlue deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:00 am
RDU
-
CTG
1 stop7h 50m
JetBlue
Fri 2/63:55 pm
CTG
-
RDU
1 stop7h 04m
JetBlue
Deal found 1/15$297
This Copa Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/43:12 pm
RDU
-
MDE
1 stop17h 06m
Copa Airlines
Sun 2/85:00 am
MDE
-
RDU
1 stop8h 14m
Copa Airlines
Deal found 1/15$297

Cheapflights Fare Finder

 
Customize your flight search to find flights from Raleigh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Raleigh to South America that are best for you.

Fly from

Raleigh

Fly to

South America

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 2/2

3:12 pm-8:18 am

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Fri 2/6

6:25 am-1:14 pm

1 stop6h 49m

$252

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Fri 3/20

4:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Mon 3/23

5:00 am-2:23 pm

1 stop8h 23m

$252

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 3/1

3:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Sun 3/8

5:00 am-2:23 pm

1 stop8h 23m

$252

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Fri 2/6

3:12 pm-8:41 am

1 stop17h 29m

Cartagena Rafael Nunez

Wed 2/11

6:25 am-1:14 pm

1 stop6h 49m

$259

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Wed 2/4

3:12 pm-8:41 am

1 stop17h 29m

Cartagena Rafael Nunez

Sun 2/8

6:25 am-1:14 pm

1 stop6h 49m

$259

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 2/28

8:19 pm-1:30 pm

2 stops17h 11m

Cartagena Rafael Nunez

Sat 3/7

4:30 pm-11:23 am

2 stops18h 53m

$294

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Sat 3/28

8:19 pm-2:15 pm

2 stops18h 56m

Cartagena Rafael Nunez

Fri 4/3

3:20 pm-10:33 am

2 stops18h 13m

$294

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Wed 2/4

7:35 pm-3:30 pm

2 stops19h 55m

Cartagena Rafael Nunez

Sun 2/8

4:30 pm-11:33 am

2 stops19h 03m

$294

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 2/2

7:00 am-2:50 pm

1 stop7h 50m

Cartagena Rafael Nunez

Fri 2/6

3:55 pm-10:59 pm

1 stop7h 04m

$297

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 2/4

3:12 pm-8:18 am

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Sun 2/8

5:00 am-1:14 pm

1 stop8h 14m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 60 results
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Best time to book a flight from Raleigh to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Raleigh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Raleigh to South America

What is the cheapest month to book a flight from Raleigh to South America?

Currently, November is the cheapest month in which you can book a flight from Raleigh to South America (average of $172). Flying from Raleigh to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 16, 2026.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Raleigh to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,050 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,050 reviews
Delta
7.9
Good
8,050 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,559 reviews
Delta
7.9
Good
8,050 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,906 reviews
Delta
7.9
Good
8,050 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,163 reviews
Delta
7.9
Good
8,050 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,135 reviews
Delta
7.9
Good
8,050 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Raleigh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Raleigh to South America?

    Raleigh-Durham (RDU) is the airport you will fly out of if you book a flight from Raleigh to South America. It is only a 11.1 mi journey to Raleigh-Durham (RDU) from Raleigh’s city center.

  • How long is the flight from Raleigh to South America?

    Copa Airlines, American Airlines, and United Airlines can get you from Raleigh to South America in just under 12h 26m. Your travel time can differ by up to 4h 45m. There are 2173 mi between Raleigh and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Raleigh to South America one-way?

    For one-way options, check prices for Copa Airlines. According to our data, you can fly for as low as $105. Users have also found prices from $128 and $142 on American Airlines and JetBlue, respectively.

  • What are the most popular routes from Raleigh to South America?

    The most popular route from Raleigh to South America is Raleigh-Durham - Medellín Jose Maria Cordova Intl. You may also consider Raleigh-Durham - Lima J Chavez Intl or Raleigh-Durham - Rio de Janeiro–Galeão Intl.

  • Can I find deals for flights from Raleigh to South America that include hotel bookings?

    Yes. In addition to deals on Raleigh to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Raleigh to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Raleigh to South America.

  • Can I find deals for business class flights from Raleigh to South America?

    Yes. Cheapflights offers flight deals from Raleigh to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Raleigh to South America?

    Currently, November is the cheapest month in which you can book a flight from Raleigh to South America (average of $172). Flying from Raleigh to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Raleigh to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Raleigh to South America

Discover the top 8 airlines that operate flights from Raleigh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$161Average$674FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$183Average$458FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$225Average$596FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$245Average$609FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$264Average$615FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$283Average$716FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$297Average$430FlexibilityNo cancel feeOn-time62%
GOLCheapest$447Average$1,208FlexibilityNo cancel feeOn-time74%

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