$118+ Cheap flights from Raleigh (RDU) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
May 22 — May 291
Round-trip
1 adult, Economy
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Find cheap flights from Raleigh to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Raleigh to South AmericaExplore the most affordable flight options available from Raleigh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
Explore the most affordable flight options available from Raleigh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:37 pm
RDU
- CTG
1 stop15h 49m
Spirit Airlines
Wed 5/201:31 pm
CTG
- RDU
1 stop20h 21m
Spirit Airlines
Deal found 4/19![Spirit Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:03 am
RDU
- CTG
1 stop6h 01m
American Airlines
Thu 4/303:10 pm
CTG
- RDU
1 stop7h 49m
American Airlines
Deal found 4/20![American Airlines logo]()
$289
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Mon 5/115:00 am
MDE
- RDU
1 stop8h 29m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:05 am
RDU
- GYE
2 stops17h 07m
American Airlines
Mon 5/112:31 pm
GYE
- RDU
2 stops17h 50m
American Airlines
Deal found 4/21![American Airlines logo]()
$295
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:19 pm
RDU
- CTG
1 stop17h 21m
Copa Airlines
Wed 5/136:20 am
CTG
- RDU
1 stop7h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$298
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:21 pm
RDU
- CTG
1 stop17h 18m
Copa Airlines
Mon 9/76:17 am
CTG
- RDU
1 stop7h 11m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Sat 5/166:20 pm
MDE
- RDU
1 stop19h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:55 pm
RDU
- CTG
1 stop19h 09m
American Airlines
Thu 5/213:15 pm
CTG
- RDU
2 stops18h 07m
American Airlines
Deal found 4/20![American Airlines logo]()
$301
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:20 pm
RDU
- MDE
1 stop16h 55m
Copa Airlines
Mon 6/85:00 am
MDE
- RDU
1 stop8h 29m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$301
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Wed 5/66:25 am
MDE
- RDU
1 stop7h 04m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:05 am
RDU
- MDE
2 stops16h 10m
American Airlines
Tue 5/121:53 pm
MDE
- RDU
2 stops17h 13m
American Airlines
Deal found 4/22![American Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:19 pm
RDU
- MDE
1 stop18h 21m
Copa Airlines
Tue 5/56:20 pm
MDE
- RDU
1 stop19h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$308
Best flights from Raleigh to South AmericaDiscover carefully curated flight deals from Raleigh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
Discover carefully curated flight deals from Raleigh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:30 am
RDU
- CTG
1 stop6h 39m
American Airlines
Thu 4/301:25 pm
CTG
- RDU
2 stops18h 23m
American Airlines
Deal found 4/19![American Airlines logo]()
$294
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:20 pm
RDU
- MDE
1 stop16h 55m
Copa Airlines
Mon 6/85:00 am
MDE
- RDU
1 stop8h 29m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$301
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:18 am
RDU
- CTG
1 stop9h 02m
Delta
Sat 5/22:35 pm
CTG
- RDU
1 stop8h 45m
Delta
Deal found 4/18![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:15 am
RDU
- MDE
1 stop15h 55m
United Airlines
Thu 5/219:45 am
MDE
- RDU
2 stops36h 44m
United Airlines
Deal found 4/20![United Airlines logo]()
$389
This JetBlue deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:15 am
RDU
- MDE
1 stop7h 47m
JetBlue
Thu 5/141:25 pm
MDE
- RDU
1 stop8h 41m
JetBlue
Deal found 4/17![JetBlue logo]()
$449
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:47 am
RDU
- GYE
1 stop12h 17m
Multiple Airlines
Fri 10/212:30 pm
GYE
- RDU
1 stop8h 37m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$473
This KAYAK deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:45 am
RDU
- LIM
2 stops13h 35m
LATAM Airlines
Sat 8/298:15 am
LIM
- RDU
1 stop11h 45m
LATAM Airlines
Deal found 4/21![LATAM Airlines logo]()
$559
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Sun 6/75:00 am
MDE
- RDU
1 stop8h 29m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:55 pm
RDU
- CTG
1 stop19h 09m
American Airlines
Thu 5/213:15 pm
CTG
- RDU
1 stop7h 44m
American Airlines
Deal found 4/21![American Airlines logo]()
$326
This GOL deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:45 pm
RDU
- GIG
1 stop13h 35m
GOL
Wed 6/242:55 pm
GIG
- RDU
2 stops26h 03m
GOL
Deal found 4/19![GOL logo]()
$700
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:55 pm
RDU
- CTG
1 stop18h 03m
Delta
Sat 5/232:30 pm
CTG
- RDU
1 stop8h 48m
Delta
Deal found 4/21![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:25 pm
RDU
- CTG
2 stops19h 10m
American Airlines
Mon 6/13:15 pm
CTG
- RDU
1 stop18h 05m
American Airlines
Deal found 4/17![American Airlines logo]()
$332
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:19 pm
RDU
- BOG
1 stop8h 47m
Copa Airlines
Wed 5/274:59 am
BOG
- RDU
1 stop8h 30m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:32 am
RDU
- BOG
2 stops12h 28m
United Airlines
Wed 5/278:30 am
BOG
- RDU
1 stop12h 29m
United Airlines
Deal found 4/20![United Airlines logo]()
$402
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:30 am
RDU
- BOG
2 stops13h 40m
Delta
Wed 6/311:00 am
BOG
- RDU
2 stops12h 16m
Delta
Deal found 4/20![Delta logo]()
$370
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:21 pm
RDU
- BOG
1 stop9h 01m
Copa Airlines
Mon 9/284:59 am
BOG
- RDU
1 stop8h 29m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:28 am
RDU
- BOG
2 stops14h 42m
Delta
Mon 5/188:40 am
BOG
- RDU
2 stops14h 36m
Delta
Deal found 4/18![Delta logo]()
$370
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:08 pm
RDU
- CTG
2 stops19h 05m
American Airlines
Thu 7/23:13 pm
CTG
- RDU
1 stop7h 46m
American Airlines
Deal found 4/17![American Airlines logo]()
$376
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:15 am
RDU
- MDE
1 stop15h 55m
United Airlines
Sat 5/169:45 am
MDE
- RDU
2 stops23h 22m
United Airlines
Deal found 4/21![United Airlines logo]()
$417
This BusinessClass deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:52 pm
RDU
- VCP
1 stop21h 53m
Azul
Wed 8/510:45 pm
VCP
- RDU
1 stop23h 49m
Azul
Deal found 4/17![Azul logo]()
$938
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
RDU
- CTG
1 stop17h 21m
Copa Airlines
Mon 6/16:20 am
CTG
- RDU
1 stop7h 09m
Copa Airlines
Deal found 4/17![Copa Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:45 am
RDU
- BOG
2 stops12h 25m
Delta
Thu 9/2411:00 am
BOG
- RDU
2 stops20h 51m
Delta
Deal found 4/19![Delta logo]()
$370
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:03 am
RDU
- CTG
1 stop6h 01m
American Airlines
Sat 5/21:25 pm
CTG
- RDU
2 stops17h 41m
American Airlines
Deal found 4/19![American Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:30 am
RDU
- BOG
2 stops13h 40m
Delta
Sun 6/72:55 pm
BOG
- RDU
1 stop8h 47m
Delta
Deal found 4/20![Delta logo]()
$370
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:18 am
RDU
- UIO
2 stops18h 22m
Multiple Airlines
Thu 5/211:30 pm
UIO
- RDU
2 stops18h 46m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$595
This Copa Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Wed 5/275:40 am
MDE
- RDU
1 stop7h 49m
Copa Airlines
Deal found 4/19![Copa Airlines logo]()
$407
This KAYAK deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:31 am
RDU
- UIO
2 stops22h 12m
LATAM Airlines
Sun 7/56:30 pm
UIO
- RDU
2 stops26h 25m
LATAM Airlines
Deal found 4/17![LATAM Airlines logo]()
$599
This JetBlue deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:15 am
RDU
- GYE
1 stop8h 11m
JetBlue
Thu 5/214:15 pm
GYE
- RDU
1 stop16h 01m
JetBlue
Deal found 4/20![JetBlue logo]()
$653
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:04 am
RDU
- MDE
2 stops15h 26m
Delta
Tue 5/196:20 am
MDE
- RDU
2 stops13h 31m
Delta
Deal found 4/19![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:15 am
RDU
- GYE
2 stops36h 14m
United Airlines
Tue 5/2612:22 pm
GYE
- RDU
3 stops24h 39m
United Airlines
Deal found 4/19![United Airlines logo]()
$549
Last-minute flights from Raleigh to South AmericaDiscover last-minute flight deals from Raleigh to South America. Data last updated April 22, 2026 and is based on user searches.
Discover last-minute flight deals from Raleigh to South America. Data last updated April 22, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:18 am
RDU
- CTG
1 stop9h 02m
Delta
Sat 5/22:35 pm
CTG
- RDU
1 stop8h 45m
Delta
Deal found 4/18![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:18 pm
RDU
- MDE
1 stop16h 57m
Copa Airlines
Sat 5/26:20 pm
MDE
- RDU
1 stop19h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:03 am
RDU
- CTG
1 stop6h 01m
American Airlines
Thu 4/303:10 pm
CTG
- RDU
1 stop7h 49m
American Airlines
Deal found 4/20![American Airlines logo]()
$289
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Wed 5/66:25 am
MDE
- RDU
1 stop7h 04m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:19 pm
RDU
- MDE
1 stop18h 21m
Copa Airlines
Tue 5/56:20 pm
MDE
- RDU
1 stop19h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:37 pm
RDU
- CTG
1 stop15h 49m
Spirit Airlines
Wed 5/201:31 pm
CTG
- RDU
1 stop20h 21m
Spirit Airlines
Deal found 4/19![Spirit Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Sat 5/166:20 pm
MDE
- RDU
1 stop19h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$300
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Mon 5/115:00 am
MDE
- RDU
1 stop8h 29m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:05 am
RDU
- MDE
2 stops16h 10m
American Airlines
Tue 5/121:53 pm
MDE
- RDU
2 stops17h 13m
American Airlines
Deal found 4/22![American Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:05 am
RDU
- GYE
2 stops17h 07m
American Airlines
Mon 5/112:31 pm
GYE
- RDU
2 stops17h 50m
American Airlines
Deal found 4/21![American Airlines logo]()
$295
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/104:19 pm
RDU
- CTG
1 stop17h 21m
Copa Airlines
Wed 5/136:20 am
CTG
- RDU
1 stop7h 09m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:55 pm
RDU
- CTG
1 stop19h 09m
American Airlines
Thu 5/213:15 pm
CTG
- RDU
2 stops18h 07m
American Airlines
Deal found 4/20![American Airlines logo]()
$301
One-way flights from Raleigh to South AmericaSearch for one-way flight options from Raleigh to South America. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
Search for one-way flight options from Raleigh to South America. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:20 pm
RDU
- CTG
1 stop7h 40m
Copa Airlines
Deal found 4/22![Copa Airlines logo]()
$118
This Copa Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Deal found 4/19![Copa Airlines logo]()
$122
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:13 pm
RDU
- CTG
2 stops18h 51m
American Airlines
Deal found 4/21![American Airlines logo]()
$124
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:15 am
RDU
- MDE
1 stop15h 55m
United Airlines
Deal found 4/20![United Airlines logo]()
$128
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:05 am
RDU
- MDE
2 stops16h 10m
American Airlines
Deal found 4/20![American Airlines logo]()
$131
This KAYAK deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm
RDU
- MDE
2 stops25h 40m
Azul
Deal found 4/18![Azul logo]()
$133
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:29 pm
RDU
- CTG
2 stops19h 06m
American Airlines
Deal found 4/19![American Airlines logo]()
$135
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:18 pm
RDU
- MDE
1 stop7h 32m
Copa Airlines
Deal found 4/17![Copa Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:19 pm
RDU
- MDE
1 stop16h 56m
Copa Airlines
Deal found 4/19![Copa Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:59 pm
RDU
- MDE
3 stops34h 51m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$143
This KAYAK deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:26 pm
RDU
- MDE
2 stops28h 44m
Copa Airlines
Deal found 4/21![Copa Airlines logo]()
$146
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:26 pm
RDU
- MDE
2 stops28h 44m
United Airlines
Deal found 4/17![United Airlines logo]()
$147
Find flight deals from Raleigh to South America
Keep the following information in mind while searching for Raleigh to South America flight deals. Data was last updated April 22, 2026.
Round-trip from | $279 (Kiwi.com) |
|---|---|
One-way from | $118 (Copa Airlines) |
Popular in | December |
Cheapest in | November |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from Raleigh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Raleigh to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighCartagena
RDU - CTG
RDUCTG
Raleigh-Durham
Mon 4/27
6:30 am-12:09 pm
1 stop6h 39m
Cartagena Rafael Nunez
Thu 4/30
1:25 pm-8:48 am
2 stops18h 23m
$294
RaleighMedellín
RDU - MDE
RDUMDE
Raleigh-Durham
Fri 6/5
4:20 pm-8:15 am
1 stop16h 55m
Medellín Jose Maria Cordova Intl
Mon 6/8
5:00 am-2:29 pm
1 stop8h 29m
$301
RaleighCartagena
RDU - CTG
RDUCTG
Raleigh-Durham
Sat 4/25
5:18 am-1:20 pm
1 stop9h 02m
Cartagena Rafael Nunez
Sat 5/2
2:35 pm-12:20 am
1 stop8h 45m
$309
RaleighMedellín
RDU - MDE
RDUMDE
Raleigh-Durham
Fri 5/29
4:19 pm-8:15 am
1 stop16h 56m
Medellín Jose Maria Cordova Intl
Sun 6/7
5:00 am-2:29 pm
1 stop8h 29m
$313
RaleighCartagena
RDU - CTG
RDUCTG
Raleigh-Durham
Sat 5/16
7:55 pm-2:04 pm
1 stop19h 09m
Cartagena Rafael Nunez
Thu 5/21
3:15 pm-11:59 pm
1 stop7h 44m
$326
RaleighCartagena
RDU - CTG
RDUCTG
Raleigh-Durham
Fri 5/29
6:25 pm-12:35 pm
2 stops19h 10m
Cartagena Rafael Nunez
Mon 6/1
3:15 pm-10:20 am
1 stop18h 05m
$332
RaleighBogotá
RDU - BOG
RDUBOG
Raleigh-Durham
Sun 5/24
4:19 pm-12:06 am
1 stop8h 47m
Bogotá El Dorado
Wed 5/27
4:59 am-2:29 pm
1 stop8h 30m
$353
RaleighBogotá
RDU - BOG
RDUBOG
Raleigh-Durham
Fri 9/11
4:21 pm-12:22 am
1 stop9h 01m
Bogotá El Dorado
Mon 9/28
4:59 am-2:28 pm
1 stop8h 29m
$353
RaleighCartagena
RDU - CTG
RDUCTG
Raleigh-Durham
Mon 5/18
7:55 pm-12:58 pm
1 stop18h 03m
Cartagena Rafael Nunez
Sat 5/23
2:30 pm-12:18 am
1 stop8h 48m
$361
RaleighCartagena
RDU - CTG
RDUCTG
Raleigh-Durham
Fri 5/29
4:19 pm-8:40 am
1 stop17h 21m
Cartagena Rafael Nunez
Mon 6/1
6:20 am-2:29 pm
1 stop7h 09m
$369
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Raleigh to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Raleigh with our price prediction graph.
RDU-CTG
RDU-MDE
RDU-GYE
RDU-VCP
RDU-BOG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Raleigh to South America
RDU-0SA
RDU-CTG
RDU-MDE
RDU-GYE
RDU-VCP
What is the cheapest month to book a flight from Raleigh to South America?
Currently, January is the cheapest month in which you can book a flight from Raleigh to South America (average of $97). Flying from Raleigh to South America in February is currently the most expensive (average of $1,210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 22, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Raleigh to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Raleigh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Raleigh to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Raleigh to South America by cabin class
Find flights from Raleigh to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Raleigh and South America flights
Browse other Raleigh and South America flight options. Last updated on April 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Raleigh to South America flights
Consider these flights traveling from Raleigh to South America.
Top 8 airlines flying from Raleigh to South America
Discover the top 8 airlines that operate flights from Raleigh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$102 | Average$649 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$143 | Average$633 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$183 | Average$452 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$197 | Average$467 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$216 | Average$559 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$264 | Average$617 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$683 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$447 | Average$1,290 | FlexibilityNo cancel fee | On-time74% |