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$146+ Cheap flights from Massachusetts to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — BOG
Nov 7 — Nov 141
Fri 11/7
Fri 11/14
1 adult, Economy
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Find flight deals from Massachusetts to South America

Cheapest flights from Massachusetts to South America
Explore the most affordable flight options available from Massachusetts to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:16 amBOS - MDE
1 stop18h 41mSpirit Airlines
Tue 11/183:14 pmMDE - BOS
1 stop8h 45mSpirit Airlines
Deal found 10/6$332
This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:16 amBOS - MDE
1 stop18h 41mSpirit Airlines
Mon 11/173:14 pmMDE - BOS
1 stop8h 45mSpirit Airlines
Deal found 10/6$333
This KAYAK deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:59 pmBOS - MDE
2 stops11h 58mSpirit Airlines
Sun 11/161:52 amMDE - BOS
1 stop22h 07mSpirit Airlines
Deal found 10/6$334
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:24 pmBOS - BOG
1 stop17h 51mSpirit Airlines
Thu 11/63:15 pmBOG - BOS
1 stop8h 44mSpirit Airlines
Deal found 10/6$335
This Mytrip deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/213:00 pmBOS - BOG
2 stops18h 14mMultiple Airlines
Fri 10/241:25 pmBOG - BOS
2 stops21h 01mMultiple Airlines
Deal found 10/7$337
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:31 pmBOS - MDE
1 stop12h 50mSpirit Airlines
Fri 11/71:52 amMDE - BOS
1 stop22h 07mSpirit Airlines
Deal found 10/6$337
This Cheapflightsfares deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:16 amBOS - BOG
1 stop7h 54mSpirit Airlines
Sat 11/83:15 pmBOG - BOS
1 stop8h 44mSpirit Airlines
Deal found 10/7$338
This Flysmarter deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:46 pmBOS - MDE
1 stop18h 46mJetBlue
Fri 10/311:10 pmMDE - BOS
1 stop9h 01mJetBlue
Deal found 10/8$339
This Cheapflightsfares deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:16 amBOS - BOG
1 stop7h 59mSpirit Airlines
Sat 11/83:15 pmBOG - BOS
1 stop8h 44mSpirit Airlines
Deal found 10/6$340
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:16 amBOS - MDE
1 stop31h 47mMultiple Airlines
Fri 11/141:52 amMDE - BOS
2 stops31h 08mMultiple Airlines
Deal found 10/7$340
This CheapOair deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:45 amBOS - MDE
1 stop8h 18mSpirit Airlines
Tue 12/23:14 pmMDE - BOS
1 stop8h 39mSpirit Airlines
Deal found 10/7$342
This Cheapflightsfares deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/208:24 pmBOS - MDE
1 stop17h 47mSpirit Airlines
Thu 10/232:22 pmMDE - BOS
1 stop8h 37mSpirit Airlines
Deal found 10/8$343

Cheap flight deals from Massachusetts to South America

Keep the following information in mind while searching for Massachusetts to South America flight deals. Data was last updated October 8, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$332
(Cheapflightsfares)

One-way from

$146
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$617

Good round-trip deal

$453 or less

Good one-way deal

$238 or less
Provider with most accurate pricing for Boston Logan Intl-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Sao Paulo (SAO) flights.
Search Deals
From Massachusetts to South America
Search Deals
One-way flight from Massachusetts to South America
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($97 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($42 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Massachusetts to South America.
Search Deals
Price to beat on a one-way flight from Massachusetts to South America.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 8, 2025.
Use the filters below to find and compare flights from Massachusetts to South America that are best for you.

Fly from

Massachusetts

Fly to

South America

Route

Depart

Return

Price

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sun 2/1

5:45 am-9:40 pm

1 stop15h 55m

Medellín Jose Maria Cordova Intl

Wed 2/4

1:00 pm-12:40 am

1 stop11h 40m

$342

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Wed 11/12

6:16 am-9:40 pm

1 stop15h 24m

Medellín Jose Maria Cordova Intl

Sun 11/16

1:00 pm-11:59 pm

1 stop10h 59m

$367

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sat 11/15

1:36 pm-12:57 am

2 stops11h 21m

Medellín Jose Maria Cordova Intl

Mon 11/24

3:14 pm-11:53 pm

1 stop8h 39m

$375

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Tue 11/18

8:15 am-7:30 pm

1 stop11h 15m

Bogotá El Dorado

Mon 11/24

3:55 pm-1:26 am

1 stop9h 31m

$409

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Wed 10/29

7:00 am-10:35 pm

1 stop16h 35m

Bogotá El Dorado

Thu 11/6

1:30 am-9:35 pm

1 stop20h 05m

$409

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Sat 3/14

8:00 am-7:30 pm

1 stop12h 30m

Bogotá El Dorado

Sun 3/22

2:55 pm-10:02 am

1 stop18h 07m

$409

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Mon 3/16

5:40 am-1:35 pm

1 stop8h 55m

Bogotá El Dorado

Tue 3/17

2:55 pm-10:02 am

1 stop18h 07m

$409

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Sat 12/13

7:10 am-8:20 pm

1 stop13h 10m

Bogotá El Dorado

Thu 2/12

9:00 am-8:27 pm

1 stop11h 27m

$409

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Mon 12/8

9:15 pm-2:25 pm

1 stop17h 10m

Bogotá El Dorado

Sat 12/13

3:55 pm-1:27 am

1 stop9h 32m

$409

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Fri 11/7

5:40 am-7:30 pm

1 stop13h 50m

Bogotá El Dorado

Fri 11/14

3:55 pm-10:03 am

1 stop18h 08m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/6

Showing 1-10 of 60 results
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Best time to book a flight from Massachusetts to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to South America

What is the cheapest month to book a flight from Massachusetts to South America?

Currently, December is the cheapest month in which you can book a flight from Massachusetts to South America (average of $167). Flying from Massachusetts to South America in April is currently the most expensive (average of $311). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to SA?

Find hourly flight availability from Massachusetts to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 8, 2025.

A simple way to save on the total cost of your ticket is to fly from Massachusetts to South America in the evening. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Massachusetts to South America?

Use this chart to determine the cheapest time to fly round-trip from Massachusetts to South America. Price data was last updated on October 5, 2025.

Travelers seeking maximum savings on their Massachusetts to South America flight should consider departing on Thursday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Massachusetts to South America flight route?

    This flight path from Massachusetts to South America was viewed by 20 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Massachusetts to South America?

    Spirit Airlines, Delta, and Copa Airlines can get you from Massachusetts to South America in just under 11h 15m. Your travel time can differ by up to 7h 31m. Massachusetts and South America are separated by a distance of 2608 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Massachusetts to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $150. JetBlue flights start at $158 while deals on LATAM Airlines start at $184 one-way.

  • Can I find deals for flights from Massachusetts to South America that include hotel bookings?

    Yes. In addition to deals on Massachusetts to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to South America.

  • Can I find deals for business class flights from Massachusetts to South America?

    Yes. Cheapflights offers flight deals from Massachusetts to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to South America?

    Currently, December is the cheapest month in which you can book a flight from Massachusetts to South America (average of $167). Flying from Massachusetts to South America in April is currently the most expensive (average of $311). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 10 airlines flying from Massachusetts to South America

Discover the top 10 airlines that operate flights from Massachusetts to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$234Average$749FlexibilityNo cancel feeOn-time69%
Spirit AirlinesCheapest$248Average$535FlexibilityNo cancel feeOn-time65%
AviancaCheapest$294Average$593FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$307Average$701FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$308Average$736FlexibilityNo cancel feeOn-time81%
DeltaCheapest$311Average$830FlexibilityNo cancel feeOn-timeN/A
GOLCheapest$340Average$781FlexibilityNo cancel feeOn-time74%
American AirlinesCheapest$340Average$792FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$396Average$579FlexibilityNo cancel feeOn-time62%
Air CanadaCheapest$590Average$764FlexibilityNo cancel feeOn-time67%

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