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$124+ Cheap flights from Massachusetts to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — BOG
Feb 18 — Feb 251
Wed 2/18
Wed 2/25
1 adult, Economy
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Cheap flight deals from Massachusetts to South America

Keep the following information in mind while searching for Massachusetts to South America flight deals. Data was last updated January 19, 2026.

Round-trip from

$287
(Kiwi.com)

One-way from

$124
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$441

Good round-trip deal

$401 or less

Good one-way deal

$243 or less
From Massachusetts to South America
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One-way flight from Massachusetts to South America
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Highest demand for flights based on searches. 11% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from Massachusetts to South America.
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Price to beat on a one-way flight from Massachusetts to South America.
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Find flight deals from Massachusetts to South America

Cheapest flights from Massachusetts to South America
Explore the most affordable flight options available from Massachusetts to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 19, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:34 am
BOS
-
MDE
1 stop8h 41m
Spirit Airlines
Wed 2/183:15 pm
MDE
-
BOS
1 stop8h 29m
Spirit Airlines
Deal found 1/18$287
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:34 am
BOS
-
MDE
1 stop8h 41m
Spirit Airlines
Wed 2/183:15 pm
MDE
-
BOS
1 stop8h 29m
Spirit Airlines
Deal found 1/17$291
This Cheapflightsfares deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:34 am
BOS
-
MDE
1 stop8h 41m
Spirit Airlines
Wed 2/43:15 pm
MDE
-
BOS
1 stop8h 42m
Spirit Airlines
Deal found 1/18$293
This Expedia deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:00 am
BOS
-
MDE
1 stop29h 03m
Avianca
Wed 5/68:20 pm
MDE
-
BOS
1 stop9h 55m
Avianca
Deal found 1/17$297
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:34 am
BOS
-
MDE
1 stop8h 41m
Spirit Airlines
Tue 2/173:15 pm
MDE
-
BOS
1 stop8h 29m
Spirit Airlines
Deal found 1/18$299
This FlightHub deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/57:55 am
BOS
-
MDE
1 stop9h 10m
Avianca
Mon 2/94:15 pm
MDE
-
BOS
1 stop14h 20m
Avianca
Deal found 1/19$301
This FlightHub deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:50 pm
BOS
-
MDE
2 stops17h 11m
Avianca
Mon 5/119:38 pm
MDE
-
BOS
1 stop8h 37m
Avianca
Deal found 1/19$303
This United Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:48 am
BOS
-
MDE
1 stop10h 17m
United Airlines
Tue 3/109:45 am
MDE
-
BOS
1 stop11h 09m
United Airlines
Deal found 1/18$306
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:05 am
BOS
-
MDE
1 stop15h 00m
United Airlines
Fri 2/610:45 am
MDE
-
BOS
2 stops26h 01m
United Airlines
Deal found 1/16$309
This Expedia deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:25 pm
BOS
-
MDE
1 stop21h 30m
Avianca
Fri 3/66:45 pm
MDE
-
BOS
1 stop11h 50m
Avianca
Deal found 1/17$310
This Priceline deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:55 am
BOS
-
BOG
Nonstop6h 30m
Avianca
Mon 2/212:10 am
BOG
-
BOS
Nonstop6h 25m
Avianca
Deal found 1/18$347
This Copa Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/267:31 am
BOS
-
BOG
1 stop9h 55m
Copa Airlines
Sat 1/3110:40 am
BOG
-
BOS
1 stop11h 23m
Copa Airlines
Deal found 1/19$348

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
Use the filters below to find and compare flights from Massachusetts to South America that are best for you.

Fly from

Massachusetts

Fly to

South America

Route

Depart

Return

Price

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sun 2/1

7:05 am-10:05 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Tue 2/17

10:45 am-11:30 pm

1 stop12h 45m

$306

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Wed 3/4

7:15 am-10:05 pm

1 stop14h 50m

Medellín Jose Maria Cordova Intl

Wed 3/11

9:45 am-11:30 pm

1 stop12h 45m

$306

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Mon 2/2

7:05 am-10:05 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Tue 2/17

10:45 am-9:31 pm

1 stop10h 46m

$306

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Thu 1/29

7:05 am-10:05 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Tue 2/17

10:45 am-9:31 pm

1 stop10h 46m

$306

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Sat 2/7

7:05 am-10:05 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Sat 2/14

10:45 am-9:31 pm

1 stop10h 46m

$306

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Mon 1/26

11:42 am-10:05 pm

1 stop10h 23m

Medellín Jose Maria Cordova Intl

Thu 2/5

10:45 am-2:29 pm

2 stops27h 44m

$311

BostonMedellín

BOS - MDE

BOSMDE

Boston Logan Intl

Mon 2/2

7:05 am-10:05 pm

1 stop15h 00m

Medellín Jose Maria Cordova Intl

Fri 2/6

10:45 am-12:46 pm

2 stops26h 01m

$311

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Fri 1/30

3:07 pm-10:10 am

1 stop19h 03m

Bogotá El Dorado

Tue 2/3

8:40 am-10:03 pm

1 stop13h 23m

$348

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Tue 3/3

8:00 am-8:20 pm

2 stops12h 20m

Bogotá El Dorado

Sat 3/7

3:55 pm-1:09 am

1 stop9h 14m

$376

BostonBogotá

BOS - BOG

BOSBOG

Boston Logan Intl

Thu 2/19

5:35 am-2:25 pm

1 stop8h 50m

Bogotá El Dorado

Tue 3/3

8:35 am-9:34 pm

2 stops12h 59m

$376

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/18

Showing 1-10 of 60 results
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Best time to book a flight from Massachusetts to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to South America

What is the cheapest month to book a flight from Massachusetts to South America?

Currently, March is the cheapest month in which you can book a flight from Massachusetts to South America (average of $216). Flying from Massachusetts to South America in July is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to SA?

Find hourly flight availability from Massachusetts to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 19, 2026.

A simple way to save on the total cost of your ticket is to fly from Massachusetts to South America in the evening. If you’re flexible enough to do this you can expect to save up to 46% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Massachusetts to South America?

Use this chart to determine the cheapest time to fly round-trip from Massachusetts to South America. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their Massachusetts to South America flight should consider departing on Thursday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Massachusetts to South America flight route?

    This flight path from Massachusetts to South America was viewed by 13 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Massachusetts to South America?

    United Airlines, Copa Airlines, and Delta can get you from Massachusetts to South America in just under 12h 20m. Your travel time can differ by up to 6h 43m. Massachusetts and South America are separated by a distance of 2608 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Massachusetts to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $111. Copa Airlines flights start at $124 while deals on American Airlines start at $125 one-way.

  • Can I find deals for flights from Massachusetts to South America that include hotel bookings?

    Yes. In addition to deals on Massachusetts to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to South America.

  • Can I find deals for business class flights from Massachusetts to South America?

    Yes. Cheapflights offers flight deals from Massachusetts to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to South America?

    Currently, March is the cheapest month in which you can book a flight from Massachusetts to South America (average of $216). Flying from Massachusetts to South America in July is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Massachusetts to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Massachusetts to South America

Discover the top 10 airlines that operate flights from Massachusetts to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$117Average$815FlexibilityNo cancel feeOn-timeN/A
ArajetCheapest$137Average$148FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$162Average$583FlexibilityNo cancel feeOn-time71%
GOLCheapest$166Average$783FlexibilityNo cancel feeOn-time74%
Copa AirlinesCheapest$206Average$683FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$234Average$701FlexibilityNo cancel feeOn-time67%
Spirit AirlinesCheapest$253Average$519FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$262Average$733FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$266Average$786FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$294Average$511FlexibilityNo cancel feeOn-time62%

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