South America

$226+ Cheap flights from Louisville (SDF) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — BOG
Nov 28 — Dec 51
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Find flight deals from Louisville to South America

Cheapest flights from Louisville to South America
Explore the most affordable flight options available from Louisville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This KAYAK deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:55 amSDF - LIM
1 stop10h 40mSpirit Airlines
Wed 12/1011:37 pmLIM - SDF
1 stop11h 23mSpirit Airlines
Deal found 10/29$463
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:00 amSDF - BOG
1 stop13h 30mDelta
Tue 12/25:00 amBOG - SDF
2 stops18h 59mDelta
Deal found 10/26$558
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:37 amSDF - BOG
2 stops25h 28mDelta
Thu 11/276:15 amBOG - SDF
2 stops27h 37mDelta
Deal found 10/26$563
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2411:00 amSDF - BOG
2 stops11h 35mUnited Airlines
Tue 12/21:30 amBOG - SDF
2 stops20h 59mUnited Airlines
Deal found 10/26$568
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:16 pmSDF - BOG
1 stop20h 09mDelta
Wed 11/265:15 pmBOG - SDF
2 stops16h 27mDelta
Deal found 10/26$570
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:10 amSDF - BOG
1 stop15h 25mUnited Airlines
Thu 11/271:30 amBOG - SDF
1 stop18h 24mUnited Airlines
Deal found 10/26$573
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/239:00 amSDF - BOG
2 stops13h 35mUnited Airlines
Tue 11/251:30 amBOG - SDF
2 stops15h 46mUnited Airlines
Deal found 10/26$578
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:10 amSDF - BOG
1 stop15h 25mUnited Airlines
Thu 11/271:30 amBOG - SDF
1 stop11h 55mUnited Airlines
Deal found 10/26$593
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:35 pmSDF - BOG
1 stop31h 00mUnited Airlines
Wed 12/38:15 amBOG - SDF
2 stops27h 17mUnited Airlines
Deal found 10/28$598
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:00 amSDF - BOG
2 stops15h 35mUnited Airlines
Thu 11/278:15 amBOG - SDF
1 stop11h 39mUnited Airlines
Deal found 10/26$603
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:35 pmSDF - BOG
1 stop13h 35mUnited Airlines
Wed 11/268:15 amBOG - SDF
1 stop13h 42mUnited Airlines
Deal found 10/26$613
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:16 pmSDF - LIM
1 stop10h 44mDelta
Sun 12/1412:15 pmLIM - SDF
1 stop10h 43mDelta
Deal found 10/29$665

Cheap flight deals from Louisville to South America

Keep the following information in mind while searching for Louisville to South America flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$458
(Kiwi.com)

One-way from

$226
(Kiwi.com)
Provider with most accurate pricing for Louisville Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Louisville Intl-Sao Paulo (SAO) flights.
From Louisville Intl to South America
One-way flight from Louisville Intl to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Louisville to South America that are best for you.

Fly from

Louisville

Fly to

South America

Route

Depart

Return

Price

LouisvilleLima

SDF - LIM

SDFLIM

Louisville Intl

Mon 1/12

10:55 am-10:58 pm

1 stop12h 03m

Lima J Chavez Intl

Sun 1/25

11:59 pm-9:54 am

1 stop9h 55m

$476

LouisvilleLima

SDF - LIM

SDFLIM

Louisville Intl

Mon 1/12

6:54 pm-10:58 pm

1 stop28h 04m

Lima J Chavez Intl

Sat 1/24

2:55 am-10:07 am

2 stops31h 12m

$486

LouisvilleBarranquilla

SDF - BAQ

SDFBAQ

Louisville Intl

Mon 1/26

6:00 am-11:37 pm

2 stops17h 37m

Barranquilla E Cortissoz

Mon 2/9

9:08 am-7:31 pm

2 stops34h 23m

$547

LouisvilleLima

SDF - LIM

SDFLIM

Louisville Intl

Sun 12/7

11:55 am-10:35 pm

1 stop10h 40m

Lima J Chavez Intl

Wed 12/10

11:37 pm-11:00 am

1 stop11h 23m

$553

LouisvilleBogotá

SDF - BOG

SDFBOG

Louisville Intl

Sun 11/23

6:00 am-7:30 pm

1 stop13h 30m

Bogotá El Dorado

Tue 12/2

5:00 am-11:59 pm

2 stops18h 59m

$558

LouisvilleBogotá

SDF - BOG

SDFBOG

Louisville Intl

Mon 2/16

9:30 am-7:15 am

2 stops21h 45m

Bogotá El Dorado

Thu 2/19

5:15 am-8:40 am

2 stops27h 25m

$558

LouisvilleBogotá

SDF - BOG

SDFBOG

Louisville Intl

Mon 2/16

6:00 am-10:35 pm

1 stop16h 35m

Bogotá El Dorado

Wed 2/18

1:30 am-7:51 pm

1 stop18h 21m

$563

LouisvilleBogotá

SDF - BOG

SDFBOG

Louisville Intl

Mon 11/24

6:00 am-2:25 pm

1 stop8h 25m

Bogotá El Dorado

Tue 12/2

5:00 am-11:59 pm

2 stops18h 59m

$563

LouisvilleBogotá

SDF - BOG

SDFBOG

Louisville Intl

Sun 11/23

9:00 am-5:10 am

2 stops20h 10m

Bogotá El Dorado

Tue 12/2

1:30 am-1:21 pm

1 stop11h 51m

$563

LouisvilleBogotá

SDF - BOG

SDFBOG

Louisville Intl

Mon 11/24

7:05 am-7:30 pm

1 stop12h 25m

Bogotá El Dorado

Thu 11/27

5:15 pm-7:12 pm

2 stops25h 57m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 45 results
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Best time to book a flight from Louisville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to South America

What is the cheapest month to book a flight from Louisville to South America?

Currently, October is the cheapest month in which you can book a flight from Louisville to South America (average of $129). Flying from Louisville to South America in November is currently the most expensive (average of $548). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SA?

Find hourly flight availability from Louisville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

When flying from Louisville to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 11% versus a flight in the afternoon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from Louisville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Boarding

8.2

Overall

7.9

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Louisville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Louisville to South America?

    Most people fly from Louisville Intl (SDF) if they book a flight from Louisville to South America. Louisville Intl is conveniently located just 5.3 mi from Louisville’s city center.

  • How long is the flight from Louisville to South America?

    For as low as $476, Spirit Airlines can have you in South America from Louisville in 12h 03m. There are 3510 mi between Louisville and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Louisville to South America one-way?

    $326 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $390 and $411, respectively.

  • What are the most popular routes from Louisville to South America?

  • Can I find deals for flights from Louisville to South America that include hotel bookings?

    Yes. In addition to deals on Louisville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to South America.

  • Can I find deals for business class flights from Louisville to South America?

    Yes. Cheapflights offers flight deals from Louisville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to South America?

    Currently, October is the cheapest month in which you can book a flight from Louisville to South America (average of $129). Flying from Louisville to South America in November is currently the most expensive (average of $548). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Louisville to South America

Discover the top 4 airlines that operate flights from Louisville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$254Average$491FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$514Average$690FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$542Average$742FlexibilityNo cancel feeOn-time81%
DeltaCheapest$645Average$1,002FlexibilityNo cancel feeOn-timeN/A

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