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$122+ Cheap flights from Louisiana to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — BOG
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Cheap flight deals from Louisiana to South America

Keep the following information in mind while searching for Louisiana to South America flight deals. Data was last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$191
(CheapOair)

One-way from

$122
(Cheapflightsfares)

Popular in

October

Cheapest in

January

Average price

$1,627
Provider with most accurate pricing for New Orleans Louis Armstrong-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Sao Paulo (SAO) flights.
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From Louisiana to South America
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One-way flight from Louisiana to South America
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Highest demand for flights based on searches. 18% potential increase in price ($234 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($68 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Louisiana to South America

Cheapest flights from Louisiana to South America
Explore the most affordable flight options available from Louisiana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:59 pmMSY - MDE
1 stop16h 04mSpirit Airlines
dom. 11/161:52 amMDE - MSY
1 stop13h 56mSpirit Airlines
Deal found 10/28$227
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/42:30 pmMSY - MDE
1 stop9h 27mSpirit Airlines
lun. 11/101:52 amMDE - MSY
1 stop12h 10mSpirit Airlines
Deal found 10/28$263
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/247:00 amMSY - MDE
1 stop6h 46mJetBlue
lun. 12/12:25 pmMDE - MSY
1 stop7h 50mJetBlue
Deal found 10/27$265
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/53:20 pmMSY - MDE
1 stop8h 49mSpirit Airlines
sáb. 12/133:10 pmMDE - MSY
1 stop7h 32mSpirit Airlines
Deal found 10/28$276
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/65:20 amMSY - BOG
1 stop6h 32mSpirit Airlines
mar. 12/93:05 pmBOG - MSY
1 stop7h 37mSpirit Airlines
Deal found 10/28$278
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:20 amMSY - CTG
1 stop5h 50mSpirit Airlines
lun. 12/152:15 pmCTG - MSY
1 stop8h 27mSpirit Airlines
Deal found 10/28$303
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/187:00 amMSY - MDE
1 stop14h 05mUnited Airlines
mié. 12/310:45 amMDE - MSY
1 stop10h 19mUnited Airlines
Deal found 10/27$303
This KAYAK deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/108:59 pmMSY - MDE
1 stop26h 58mSpirit Airlines
sáb. 11/222:57 pmMDE - MSY
2 stops27h 11mSpirit Airlines
Deal found 10/28$306
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/810:40 amMSY - CLO
2 stops19h 11mMultiple Airlines
mar. 11/111:13 pmCLO - MSY
2 stops21h 52mMultiple Airlines
Deal found 10/28$307
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/274:24 pmMSY - CTG
2 stops20h 01mSpirit Airlines
jue. 12/42:15 pmCTG - MSY
1 stop8h 27mSpirit Airlines
Deal found 10/28$308
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1712:01 pmMSY - MDE
1 stop9h 04mUnited Airlines
vie. 12/1210:45 amMDE - MSY
1 stop25h 12mUnited Airlines
Deal found 10/28$309
This Orbitz deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/53:20 pmMSY - MDE
1 stop8h 49mSpirit Airlines
mié. 12/102:54 pmMDE - MSY
1 stop8h 56mSpirit Airlines
Deal found 10/28$312

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Louisiana to South America that are best for you.

Fly from

Louisiana

Fly to

South America

Route

Depart

Return

Price

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

vie. 11/14

8:59 pm-2:03 pm

1 stop16h 04m

Medellín Jose Maria Cordova Intl

dom. 11/16

1:52 am-2:48 pm

1 stop13h 56m

$227

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

lun. 11/24

7:00 am-2:46 pm

1 stop6h 46m

Medellín Jose Maria Cordova Intl

lun. 12/1

2:25 pm-9:15 pm

1 stop7h 50m

$265

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

vie. 12/5

3:20 pm-1:09 am

1 stop8h 49m

Medellín Jose Maria Cordova Intl

sáb. 12/13

3:10 pm-9:42 pm

1 stop7h 32m

$276

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

mar. 11/18

7:00 am-10:05 pm

1 stop14h 05m

Medellín Jose Maria Cordova Intl

mié. 12/3

10:45 am-8:04 pm

1 stop10h 19m

$303

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

lun. 11/10

5:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

sáb. 11/22

10:45 am-8:05 pm

1 stop10h 20m

$303

New OrleansCartagena

MSY - CTG

MSYCTG

New Orleans Louis Armstrong

jue. 12/11

6:20 am-1:10 pm

1 stop5h 50m

Cartagena Rafael Nunez

lun. 12/15

2:15 pm-9:42 pm

1 stop8h 27m

$303

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

lun. 11/24

5:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

mié. 12/3

10:45 am-8:04 pm

1 stop10h 19m

$303

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

lun. 11/17

12:01 pm-10:05 pm

1 stop9h 04m

Medellín Jose Maria Cordova Intl

vie. 12/12

10:45 am-10:57 am

1 stop25h 12m

$309

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

vie. 12/5

3:20 pm-1:09 am

1 stop8h 49m

Medellín Jose Maria Cordova Intl

mié. 12/10

2:54 pm-10:50 pm

1 stop8h 56m

$312

New OrleansMedellín

MSY - MDE

MSYMDE

New Orleans Louis Armstrong

lun. 11/17

8:59 pm-2:03 pm

1 stop16h 04m

Medellín Jose Maria Cordova Intl

jue. 12/11

2:05 am-8:22 am

1 stop7h 17m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 60 results
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Best time to book a flight from Louisiana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to South America

What is the cheapest month to book a flight from Louisiana to South America?

Currently, September is the cheapest month in which you can book a flight from Louisiana to South America (average of $243). Flying from Louisiana to South America in March is currently the most expensive (average of $421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LA to SA?

Find hourly flight availability from Louisiana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Louisiana to South America in the evening. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Louisiana to South America?

Use this chart to determine the cheapest time to fly round-trip from Louisiana to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Louisiana to South America flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisiana to South America?

    Departing from Louisiana to South America will take you 6h 46m. The distance between Louisiana and South America is about 1907 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Louisiana to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $122. United Airlines flights start at $128 while deals on LATAM Airlines start at $196 one-way.

  • Can I find deals for flights from Louisiana to South America that include hotel bookings?

    Yes. In addition to deals on Louisiana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to South America.

  • Can I find deals for business class flights from Louisiana to South America?

    Yes. Cheapflights offers flight deals from Louisiana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to South America?

    Currently, September is the cheapest month in which you can book a flight from Louisiana to South America (average of $243). Flying from Louisiana to South America in March is currently the most expensive (average of $421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisiana to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Louisiana to South America

Discover the top 5 airlines that operate flights from Louisiana to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$251Average$431FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$364Average$872FlexibilityNo cancel feeOn-time69%
DeltaCheapest$365Average$745FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$372Average$931FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$375Average$702FlexibilityNo cancel feeOn-time81%

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