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South America

$438+ Cheap flights from Lexington (LEX) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — BOG
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from Lexington to South America

Best flights from Lexington to South America
Discover carefully curated flight deals from Lexington to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 31, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:12 pmLEX - LIM
2 stops28h 23mMultiple Airlines
Wed 5/1310:30 pmLIM - LEX
1 stop11h 31mMultiple Airlines
Deal found 12/29$543
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:45 pmLEX - MDE
2 stops28h 20mUnited Airlines
Thu 2/2610:45 amMDE - LEX
2 stops26h 30mUnited Airlines
Deal found 12/29$590
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:15 pmLEX - CTG
2 stops22h 54mAmerican Airlines
Tue 4/281:25 pmCTG - LEX
2 stops20h 06mAmerican Airlines
Deal found 12/30$590
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:15 amLEX - CTG
1 stop7h 03mDelta
Tue 4/282:30 pmCTG - LEX
1 stop8h 24mDelta
Deal found 12/30$609
This KAYAK deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:10 amLEX - CTG
1 stop7h 08mLATAM Airlines
Tue 5/122:30 pmCTG - LEX
1 stop8h 25mLATAM Airlines
Deal found 12/29$611
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:00 pmLEX - CTG
2 stops22h 30mAmerican Airlines
Sat 2/214:30 pmCTG - LEX
2 stops16h 58mAmerican Airlines
Deal found 12/31$615
This Delta deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:10 amLEX - CTG
1 stop7h 08mDelta
Mon 5/115:35 amCTG - LEX
2 stops26h 49mDelta
Deal found 12/29$615
This Ovago deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:15 amLEX - CTG
1 stop7h 03mLATAM Airlines
Tue 4/282:30 pmCTG - LEX
1 stop8h 24mLATAM Airlines
Deal found 12/31$630
This Delta deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:15 amLEX - CTG
2 stops17h 20mDelta
Tue 5/122:30 pmCTG - LEX
1 stop8h 25mDelta
Deal found 12/29$617
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:40 amLEX - GYE
2 stops16h 04mAmerican Airlines
Sat 5/26:05 amGYE - LEX
2 stops16h 47mAmerican Airlines
Deal found 12/30$647
This Gurufare deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:26 pmLEX - LIM
1 stop10h 29mLATAM Airlines
Wed 5/138:55 amLIM - LEX
2 stops14h 00mLATAM Airlines
Deal found 12/29$652
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:00 amLEX - UIO
2 stops17h 25mUnited Airlines
Tue 4/2812:35 amUIO - LEX
2 stops15h 27mUnited Airlines
Deal found 12/29$745
This Delta deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:19 pmLEX - CTG
1 stop23h 59mDelta
Mon 5/115:35 amCTG - LEX
2 stops26h 49mDelta
Deal found 12/29$622
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/304:35 pmLEX - LIM
2 stops12h 35mAmerican Airlines
Fri 2/610:55 pmLIM - LEX
2 stops16h 42mAmerican Airlines
Deal found 12/31$702
This LATAM Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:10 amLEX - LIM
2 stops25h 55mLATAM Airlines
Wed 8/1912:00 pmLIM - LEX
1 stop10h 55mLATAM Airlines
Deal found 12/30$714
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:30 pmLEX - LIM
2 stops16h 30mDelta
Mon 8/312:00 pmLIM - LEX
1 stop20h 24mDelta
Deal found 12/30$719
This LATAM Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:15 amLEX - UIO
2 stops16h 45mLATAM Airlines
Tue 4/2812:59 amUIO - LEX
1 stop9h 42mLATAM Airlines
Deal found 12/29$750
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/18:35 amLEX - GYE
2 stops33h 00mUnited Airlines
Thu 2/52:35 pmGYE - LEX
2 stops32h 05mUnited Airlines
Deal found 12/30$961
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:14 pmLEX - LIM
1 stop13h 46mDelta
Sat 4/118:55 amLIM - LEX
2 stops23h 25mDelta
Deal found 12/30$734
This LATAM Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/110:31 amLEX - GYE
2 stops20h 49mLATAM Airlines
Thu 2/54:30 pmGYE - LEX
2 stops25h 21mLATAM Airlines
Deal found 12/29$872
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:00 amLEX - GIG
2 stops25h 35mUnited Airlines
Thu 4/29:05 pmGIG - LEX
2 stops48h 19mUnited Airlines
Deal found 12/30$1,098
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:15 pmLEX - GIG
2 stops17h 05mAmerican Airlines
Sun 4/263:50 pmGIG - LEX
2 stops22h 45mAmerican Airlines
Deal found 12/28$1,131
This LATAM Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:14 pmLEX - SCL
1 stop15h 01mLATAM Airlines
Sat 4/1111:05 pmSCL - LEX
2 stops34h 32mLATAM Airlines
Deal found 12/30$944
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:32 pmLEX - VVI
2 stops28h 18mUnited Airlines
Mon 2/911:44 amVVI - LEX
2 stops26h 41mUnited Airlines
Deal found 12/30$1,169
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:46 pmLEX - EZE
2 stops36h 19mDelta
Mon 3/98:00 amEZE - LEX
2 stops16h 53mDelta
Deal found 12/31$1,026
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1411:39 amLEX - GIG
2 stops19h 46mAmerican Airlines
Wed 1/2111:00 pmGIG - LEX
2 stops19h 14mAmerican Airlines
Deal found 12/30$1,135
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:41 pmLEX - SCL
2 stops37h 09mUnited Airlines
Thu 3/129:45 pmSCL - LEX
2 stops16h 30mUnited Airlines
Deal found 12/29$1,177
This LATAM Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:16 amLEX - SCL
2 stops22h 44mLATAM Airlines
Sat 4/1111:05 pmSCL - LEX
2 stops34h 32mLATAM Airlines
Deal found 12/30$984
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 amLEX - EZE
2 stops22h 05mDelta
Tue 3/102:25 amEZE - LEX
2 stops22h 28mDelta
Deal found 12/31$1,102
This KAYAK deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:13 amLEX - EZE
2 stops21h 07mLATAM Airlines
Tue 3/108:55 pmEZE - LEX
1 stop13h 25mLATAM Airlines
Deal found 12/31$1,018

Find flight deals from Lexington to South America

Keep the following information in mind while searching for Lexington to South America flight deals. Data was last updated December 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$519
(Kiwi.com)

One-way from

$438
(United Airlines)
Provider with most accurate pricing for Lexington Blue Grass-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Sao Paulo (SAO) flights.
Search Deals
From Lexington Blue Grass to South America
Search Deals
One-way flight from Lexington Blue Grass to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Lexington to South America that are best for you.

Fly from

Lexington

Fly to

South America

Route

Depart

Return

Price

LexingtonLima

LEX - LIM

LEXLIM

Lexington Blue Grass

Thu 5/7

9:12 pm-12:35 am

2 stops28h 23m

Lima J Chavez Intl

Wed 5/13

10:30 pm-11:01 am

1 stop11h 31m

$543

LexingtonMedellín

LEX - MDE

LEXMDE

Lexington Blue Grass

Sun 2/22

5:45 pm-10:05 pm

2 stops28h 20m

Medellín Jose Maria Cordova Intl

Thu 2/26

10:45 am-1:15 pm

2 stops26h 30m

$590

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Tue 4/21

2:15 pm-12:09 pm

2 stops22h 54m

Cartagena Rafael Nunez

Tue 4/28

1:25 pm-10:31 am

2 stops20h 06m

$590

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Tue 4/21

7:15 am-1:18 pm

1 stop7h 03m

Cartagena Rafael Nunez

Tue 4/28

2:30 pm-11:54 pm

1 stop8h 24m

$609

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Thu 5/7

7:10 am-1:18 pm

1 stop7h 08m

Cartagena Rafael Nunez

Tue 5/12

2:30 pm-11:55 pm

1 stop8h 25m

$611

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Sat 2/14

3:00 pm-1:30 pm

2 stops22h 30m

Cartagena Rafael Nunez

Sat 2/21

4:30 pm-9:28 am

2 stops16h 58m

$615

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Thu 5/7

7:10 am-1:18 pm

1 stop7h 08m

Cartagena Rafael Nunez

Mon 5/11

5:35 am-9:24 am

2 stops26h 49m

$615

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Wed 5/6

7:15 am-11:35 pm

2 stops17h 20m

Cartagena Rafael Nunez

Tue 5/12

2:30 pm-11:55 pm

1 stop8h 25m

$617

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Wed 5/6

2:19 pm-1:18 pm

1 stop23h 59m

Cartagena Rafael Nunez

Mon 5/11

5:35 am-9:24 am

2 stops26h 49m

$622

LexingtonCartagena

LEX - CTG

LEXCTG

Lexington Blue Grass

Tue 4/21

7:15 am-1:18 pm

1 stop7h 03m

Cartagena Rafael Nunez

Tue 4/28

2:30 pm-11:54 pm

1 stop8h 24m

$630

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 35 results
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Best time to book a flight from Lexington to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to South America

What is the cheapest month to book a flight from Lexington to South America?

Currently, October is the cheapest month in which you can book a flight from Lexington to South America (average of $129). Flying from Lexington to South America in January is currently the most expensive (average of $566). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 31, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Lexington to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,069 reviews
Delta
7.9
Good
8,013 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lexington to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lexington to South America?

    Lexington Blue Grass (LEX), located 5.6 mi from the city center, is the airport you fly out of when you book flights from Lexington to South America.

  • How long is the flight from Lexington to South America?

    Airlines like United Airlines, American Airlines, and Delta fly from Lexington to South America in about 7h 03m. The time it takes to get you to your destination can typically vary by up to 21h 17m. There are 1987 mi between Lexington and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Lexington to South America?

    While some choose either Lexington Blue Grass - Buenos Aires Ministro Pistarini or Lexington Blue Grass - Cordoba Pajas Blancas, Lexington Blue Grass - Lima J Chavez Intl is the most popular route from Lexington to South America.

  • Can I find deals for flights from Lexington to South America that include hotel bookings?

    Yes. In addition to deals on Lexington to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to South America.

  • Can I find deals for business class flights from Lexington to South America?

    Yes. Cheapflights offers flight deals from Lexington to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to South America?

    Currently, October is the cheapest month in which you can book a flight from Lexington to South America (average of $129). Flying from Lexington to South America in January is currently the most expensive (average of $566). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Lexington to South America

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Top 2 airlines flying from Lexington to South America

Discover the top 2 airlines that operate flights from Lexington to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$564Average$682FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$573Average$1,530FlexibilityNo cancel feeOn-time71%

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