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South America

$310+ Cheap flights from Greenville (GSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
Aug 16 — Aug 231
Sat 8/16
Sat 8/23
1 adult, Economy
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Cheap flight deals from Greenville to South America

Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated August 11, 2025.

Round-trip from

$394
(Kiwi.com)

One-way from

$310
(American Airlines)
From Greenville to South America
Search Deals
One-way flight from Greenville to South America
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Find flight deals from Greenville to South America

Cheapest flights from Greenville to South America
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:26 pmGSP - BOG
1 stop17h 34mMultiple Airlines
Sun 9/212:05 pmBOG - GSP
2 stops27h 41mMultiple Airlines
Deal found 8/9$394
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/711:18 amGSP - MDE
1 stop26h 42mMultiple Airlines
Sun 9/144:30 pmMDE - GSP
2 stops25h 16mMultiple Airlines
Deal found 8/10$448
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:26 pmGSP - BOG
1 stop17h 34mMultiple Airlines
Mon 9/88:15 amBOG - GSP
1 stop9h 31mMultiple Airlines
Deal found 8/9$481
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1612:00 pmGSP - BOG
1 stop7h 30mLATAM Airlines
Sat 11/223:50 pmBOG - GSP
1 stop7h 47mLATAM Airlines
Deal found 8/10$506
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amGSP - MDE
1 stop15h 15mAmerican Airlines
Tue 10/286:00 amMDE - GSP
1 stop16h 21mAmerican Airlines
Deal found 8/10$506
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1612:00 pmGSP - BOG
2 stops15h 15mDelta
Sat 11/226:15 amBOG - GSP
2 stops17h 22mDelta
Deal found 8/10$513
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:05 amGSP - CTG
2 stops27h 37mUnited Airlines
Sat 10/49:42 amCTG - GSP
2 stops35h 57mUnited Airlines
Deal found 8/10$516
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:00 amGSP - MDE
1 stop15h 15mAmerican Airlines
Tue 10/286:00 amMDE - GSP
1 stop16h 21mAmerican Airlines
Deal found 8/9$516
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:34 pmGSP - MDE
2 stops28h 36mUnited Airlines
Tue 10/289:45 amMDE - GSP
2 stops25h 04mUnited Airlines
Deal found 8/9$520
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/299:45 pmGSP - MDE
2 stops24h 20mUnited Airlines
Wed 12/1710:45 amMDE - GSP
1 stop11h 13mUnited Airlines
Deal found 8/9$537
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:00 amGSP - CTG
1 stop7h 25mAmerican Airlines
Sat 10/41:25 pmCTG - GSP
1 stop9h 31mAmerican Airlines
Deal found 8/9$542
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2910:03 amGSP - CTG
2 stops14h 13mDelta
Sat 10/42:33 pmCTG - GSP
1 stop8h 01mDelta
Deal found 8/9$544

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Greenville

Fly to

South America

Route

Depart

Return

Price

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Fri 9/12

7:26 pm-12:00 pm

1 stop17h 34m

Bogotá El Dorado

Sun 9/21

2:05 pm-6:46 pm

2 stops27h 41m

$394

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 9/7

11:18 am-1:00 pm

1 stop26h 42m

Medellín Jose Maria Cordova Intl

Sun 9/14

4:30 pm-6:46 pm

2 stops25h 16m

$448

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Fri 9/5

7:26 pm-12:00 pm

1 stop17h 34m

Bogotá El Dorado

Mon 9/8

8:15 am-6:46 pm

1 stop9h 31m

$481

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sun 11/16

12:00 pm-7:30 pm

1 stop7h 30m

Bogotá El Dorado

Sat 11/22

3:50 pm-11:37 pm

1 stop7h 47m

$506

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

6:00 am-8:15 pm

1 stop15h 15m

Medellín Jose Maria Cordova Intl

Tue 10/28

6:00 am-11:21 pm

1 stop16h 21m

$506

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sun 11/16

12:00 pm-3:15 am

2 stops15h 15m

Bogotá El Dorado

Sat 11/22

6:15 am-11:37 pm

2 stops17h 22m

$513

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Mon 9/29

6:05 am-8:42 am

2 stops27h 37m

Cartagena Rafael Nunez

Sat 10/4

9:42 am-10:39 pm

2 stops35h 57m

$516

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 10/18

6:00 am-8:15 pm

1 stop15h 15m

Medellín Jose Maria Cordova Intl

Tue 10/28

6:00 am-11:21 pm

1 stop16h 21m

$516

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 10/18

5:34 pm-9:10 pm

2 stops28h 36m

Medellín Jose Maria Cordova Intl

Tue 10/28

9:45 am-11:49 am

2 stops25h 04m

$520

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 11/29

9:45 pm-10:05 pm

2 stops24h 20m

Medellín Jose Maria Cordova Intl

Wed 12/17

10:45 am-9:58 pm

1 stop11h 13m

$537

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Showing 1-10 of 39 results
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, May is the cheapest month in which you can book a flight from Greenville to South America (average of $359). Flying from Greenville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SA?

Find hourly flight availability from Greenville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2025.

When flying from Greenville to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 11, 2025.
Read through reviews of airlines operating flights from Greenville to South America, such as Delta, LATAM Airlines, and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,837 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,505 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,920 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • What are the cheapest airlines to fly from Greenville to South America one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $310. LATAM Airlines flights start at $323 while deals on Delta start at $343 one-way.

  • What are the most popular routes from Greenville to South America?

    The most popular route from Greenville to South America is Greenville - Medellín Jose Maria Cordova Intl. You may also consider Greenville - Bogotá El Dorado or Greenville - Buenos Aires Ministro Pistarini.

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, May is the cheapest month in which you can book a flight from Greenville to South America (average of $359). Flying from Greenville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Greenville to South America

Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$490Average$727FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$502Average$863FlexibilityNo cancel feeOn-time81%
DeltaCheapest$532Average$935FlexibilityNo cancel feeOn-timeN/A

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