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South America

$214+ Cheap flights from Greenville (GSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Greenville to South America

Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$510
(American Airlines)

One-way from

$214
(Kiwi.com)
Provider with most accurate pricing for Greenville-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Greenville-Sao Paulo (SAO) flights.
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From Greenville to South America
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One-way flight from Greenville to South America
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Find flight deals from Greenville to South America

Cheapest flights from Greenville to South America
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:31 amGSP - MDE
2 stops15h 24mAmerican Airlines
Tue 10/285:50 amMDE - GSP
2 stops14h 32mAmerican Airlines
Deal found 4/30$510
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:17 amGSP - BOG
1 stop16h 13mAmerican Airlines
Sat 8/166:30 amBOG - GSP
1 stop16h 00mAmerican Airlines
Deal found 4/29$513
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/285:35 pmGSP - BOG
2 stops19h 25mDelta
Tue 7/82:55 pmBOG - GSP
1 stop8h 04mDelta
Deal found 4/30$535
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2710:27 amGSP - BOG
2 stops19h 27mUnited Airlines
Tue 6/38:30 amBOG - GSP
2 stops24h 22mUnited Airlines
Deal found 4/28$537
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:46 amGSP - MDE
2 stops39h 19mUnited Airlines
Wed 12/1010:45 amMDE - GSP
1 stop11h 01mUnited Airlines
Deal found 4/29$539
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:57 amGSP - CTG
1 stop7h 13mAmerican Airlines
Sat 10/41:55 pmCTG - GSP
1 stop9h 29mAmerican Airlines
Deal found 4/30$543
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/122:19 pmGSP - CTG
3 stops46h 51mMultiple Airlines
Mon 6/166:06 amCTG - GSP
2 stops13h 27mMultiple Airlines
Deal found 4/30$570
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/127:30 amGSP - CTG
1 stop6h 45mDelta
Mon 6/167:30 amCTG - GSP
2 stops15h 27mDelta
Deal found 4/30$595
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/23:55 pmGSP - BOG
1 stop22h 09mMultiple Airlines
Sat 5/106:17 pmBOG - GSP
2 stops25h 11mMultiple Airlines
Deal found 4/29$598
This LATAM Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1410:05 amGSP - BOG
2 stops10h 53mLATAM Airlines
Fri 6/201:35 amBOG - GSP
2 stops10h 39mLATAM Airlines
Deal found 4/30$609
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:05 pmGSP - UIO
1 stop31h 20mUnited Airlines
Fri 10/1012:35 amUIO - GSP
1 stop14h 11mUnited Airlines
Deal found 4/30$632
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:00 pmGSP - LIM
1 stop17h 00mDelta
Fri 11/2812:10 amLIM - GSP
2 stops14h 39mDelta
Deal found 4/30$653

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Greenville

Fly to

South America

Route

Depart

Return

Price

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sat 8/9

7:17 am-10:30 pm

1 stop16h 13m

Bogotá El Dorado

Sat 8/16

6:30 am-11:30 pm

1 stop16h 00m

$513

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sat 6/28

5:35 pm-12:00 pm

2 stops19h 25m

Bogotá El Dorado

Tue 7/8

2:55 pm-11:59 pm

1 stop8h 04m

$535

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Tue 5/27

10:27 am-4:54 am

2 stops19h 27m

Bogotá El Dorado

Tue 6/3

8:30 am-9:52 am

2 stops24h 22m

$537

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 6/14

5:19 pm-11:35 pm

1 stop7h 16m

Medellín Jose Maria Cordova Intl

Sat 6/21

6:00 am-10:11 pm

1 stop15h 11m

$546

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Thu 6/12

2:19 pm-12:10 pm

3 stops46h 51m

Cartagena Rafael Nunez

Mon 6/16

6:06 am-8:33 pm

2 stops13h 27m

$570

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Thu 6/12

7:30 am-1:15 pm

1 stop6h 45m

Cartagena Rafael Nunez

Mon 6/16

7:30 am-11:57 pm

2 stops15h 27m

$595

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Thu 6/12

7:16 pm-2:10 pm

2 stops19h 54m

Cartagena Rafael Nunez

Mon 6/16

3:10 pm-7:42 pm

1 stop27h 32m

$600

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sat 6/14

10:05 am-7:58 pm

2 stops10h 53m

Bogotá El Dorado

Fri 6/20

1:35 am-1:14 pm

2 stops10h 39m

$609

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 5/28

6:00 am-9:10 pm

2 stops16h 10m

Medellín Jose Maria Cordova Intl

Tue 6/3

12:15 am-10:43 pm

2 stops21h 28m

$611

GreenvilleQuito

GSP - UIO

GSPUIO

Greenville

Fri 10/3

5:05 pm-11:25 pm

1 stop31h 20m

Quito Mariscal Sucr

Fri 10/10

12:35 am-3:46 pm

1 stop14h 11m

$632

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 37 results
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, May is the cheapest month in which you can book a flight from Greenville to South America (average of $359). Flying from Greenville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SA?

Find hourly flight availability from Greenville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Greenville to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated May 1, 2025.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,414 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • What are the cheapest airlines to fly from Greenville to South America one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $309. Delta flights start at $314 while deals on American Airlines start at $370 one-way.

  • What are the most popular routes from Greenville to South America?

    The most popular route from Greenville to South America is Greenville - Medellín Jose Maria Cordova Intl. You may also consider Greenville - Bogotá El Dorado or Greenville - Rio de Janeiro–Galeão Intl.

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, May is the cheapest month in which you can book a flight from Greenville to South America (average of $359). Flying from Greenville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Greenville to South America

Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$467Average$708FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$502Average$874FlexibilityNo cancel feeOn-time81%
DeltaCheapest$532Average$970FlexibilityNo cancel feeOn-timeN/A

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