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South America

$172+ Cheap flights from Greenville (GSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from Greenville to South America

Cheapest flights from Greenville to South America
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:00 pmGSP - MDE
1 stop10h 09mMultiple Airlines
Tue 12/233:10 pmMDE - GSP
1 stop24h 40mMultiple Airlines
Deal found 11/17$407
This Mytrip deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:00 pmGSP - MDE
1 stop10h 09mMultiple Airlines
Tue 12/232:54 pmMDE - GSP
2 stops24h 56mMultiple Airlines
Deal found 11/17$464
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:17 pmGSP - BOG
1 stop25h 38mMultiple Airlines
Thu 12/112:17 amBOG - GSP
1 stop11h 53mMultiple Airlines
Deal found 11/19$523
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:26 pmGSP - MDE
1 stop24h 34mMultiple Airlines
Sat 1/1710:40 amMDE - GSP
2 stops29h 39mMultiple Airlines
Deal found 11/18$527
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:41 amGSP - MDE
1 stop13h 15mMultiple Airlines
Thu 3/261:37 amMDE - GSP
1 stop15h 18mMultiple Airlines
Deal found 11/18$592
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:41 pmGSP - CTG
2 stops32h 29mMultiple Airlines
Tue 12/302:15 pmCTG - GSP
1 stop25h 40mMultiple Airlines
Deal found 11/19$616
This FlightHub deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:45 amGSP - BOG
2 stops10h 00mLATAM Airlines
Fri 12/1210:55 amBOG - GSP
2 stops11h 38mLATAM Airlines
Deal found 11/19$626
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:17 pmGSP - BOG
2 stops18h 48mDelta
Sun 12/145:25 pmBOG - GSP
2 stops15h 37mDelta
Deal found 11/19$633
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:07 pmGSP - BOG
1 stop16h 33mAmerican Airlines
Wed 12/3111:55 pmBOG - GSP
1 stop11h 33mAmerican Airlines
Deal found 11/20$648
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:10 pmGSP - LIM
1 stop24h 00mMultiple Airlines
Sat 12/64:40 pmLIM - GSP
2 stops28h 34mMultiple Airlines
Deal found 11/20$668
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:07 pmGSP - CTG
1 stop19h 23mAmerican Airlines
Tue 12/304:30 pmCTG - GSP
1 stop8h 21mAmerican Airlines
Deal found 11/19$678
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:35 amGSP - BOG
2 stops11h 10mDelta
Mon 12/157:00 amBOG - GSP
2 stops11h 44mDelta
Deal found 11/19$710

Cheap flight deals from Greenville to South America

Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated November 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$299
(Kiwi.com)

One-way from

$172
(Kiwi.com)
Provider with most accurate pricing for Greenville-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Sao Paulo (SAO) flights.
Search Deals
From Greenville to South America
Search Deals
One-way flight from Greenville to South America
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Greenville

Fly to

South America

Route

Depart

Return

Price

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Mon 2/23

6:22 pm-2:10 pm

1 stop19h 48m

Bogotá El Dorado

Wed 2/25

3:05 pm-4:23 pm

1 stop25h 18m

$311

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 12/12

3:00 pm-1:09 am

1 stop10h 09m

Medellín Jose Maria Cordova Intl

Tue 12/23

2:54 pm-3:50 pm

2 stops24h 56m

$464

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Thu 3/26

12:00 pm-7:30 pm

1 stop8h 30m

Bogotá El Dorado

Sun 4/5

8:40 am-9:27 am

2 stops23h 47m

$513

GreenvilleLima

GSP - LIM

GSPLIM

Greenville

Thu 1/22

6:45 pm-10:35 pm

1 stop27h 50m

Lima J Chavez Intl

Thu 1/29

1:50 am-8:07 pm

2 stops18h 17m

$527

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 1/23

6:05 am-9:10 pm

2 stops15h 05m

Medellín Jose Maria Cordova Intl

Sun 2/8

7:00 am-11:57 pm

1 stop16h 57m

$531

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Thu 3/26

6:30 am-11:05 pm

2 stops17h 35m

Bogotá El Dorado

Sat 4/4

12:14 am-10:00 pm

1 stop20h 46m

$534

GreenvillePereira

GSP - PEI

GSPPEI

Greenville

Sat 5/9

4:30 pm-11:24 pm

2 stops31h 54m

Pereira Matecana

Tue 5/12

6:17 am-3:18 pm

2 stops32h 01m

$541

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Sun 1/25

6:49 am-11:00 pm

2 stops16h 11m

Cartagena Rafael Nunez

Thu 1/29

3:02 pm-9:57 pm

2 stops30h 55m

$544

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 1/23

5:34 pm-10:05 pm

2 stops28h 31m

Medellín Jose Maria Cordova Intl

Sun 2/8

10:45 am-7:29 pm

2 stops32h 44m

$547

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 4/19

6:52 am-9:10 pm

1 stop15h 18m

Medellín Jose Maria Cordova Intl

Mon 5/4

9:45 am-9:46 pm

1 stop11h 01m

$548

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 50 results
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SA?

Find hourly flight availability from Greenville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

One of the essential ways to save on airfare from Greenville to South America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 25% on airfare.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 20, 2025.
Read through reviews of airlines operating flights from Greenville to South America, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,882 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • How long is the flight from Greenville to South America?

    LATAM Airlines, American Airlines, and United Airlines can get you from Greenville to South America in just under 8h 30m. Your travel time can differ by up to 9h 05m. The distance from Greenville to South America is about 2148 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Greenville to South America?

    The most popular route from Greenville to South America is Greenville - Medellín Jose Maria Cordova Intl. You may also consider Greenville - Lima J Chavez Intl or Greenville - Bogotá El Dorado.

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to South America

Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$502Average$876FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$502Average$874FlexibilityNo cancel feeOn-time71%
DeltaCheapest$532Average$923FlexibilityNo cancel feeOn-timeN/A

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