South America

$145+ Cheap flights from Greenville (GSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
May 8 — May 151
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Cheap flight deals from Greenville to South America

Cheapest flights from Greenville to South America
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:43 pm
GSP
-
BOG
1 stop20h 20m
Multiple Airlines
Sat 6/62:08 pm
BOG
-
GSP
1 stop28h 46m
Multiple Airlines
Deal found 4/3$387
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:18 pm
GSP
-
MDE
1 stop17h 42m
Multiple Airlines
Fri 5/86:20 pm
MDE
-
GSP
2 stops37h 23m
Multiple Airlines
Deal found 4/6$488
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:17 pm
GSP
-
MDE
1 stop22h 26m
Multiple Airlines
Sun 6/72:06 pm
MDE
-
GSP
1 stop21h 26m
Multiple Airlines
Deal found 4/5$495
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:06 pm
GSP
-
MDE
1 stop10h 19m
Multiple Airlines
Sun 8/161:00 pm
MDE
-
GSP
1 stop27h 39m
Multiple Airlines
Deal found 4/6$497
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
-
MDE
1 stop7h 38m
Multiple Airlines
Thu 4/1610:35 am
MDE
-
GSP
2 stops32h 03m
Multiple Airlines
Deal found 4/7$499
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
-
BOG
1 stop20h 28m
Multiple Airlines
Sun 4/196:25 am
BOG
-
GSP
2 stops33h 28m
Multiple Airlines
Deal found 4/5$510
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
-
BOG
1 stop20h 28m
Multiple Airlines
Mon 4/209:00 am
BOG
-
GSP
1 stop10h 07m
Multiple Airlines
Deal found 4/5$517
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:35 am
GSP
-
MDE
2 stops27h 25m
Multiple Airlines
Thu 5/281:55 pm
MDE
-
GSP
1 stop24h 48m
Multiple Airlines
Deal found 4/6$517
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
GSP
-
MDE
1 stop17h 32m
Multiple Airlines
Tue 5/121:55 pm
MDE
-
GSP
2 stops52h 54m
Multiple Airlines
Deal found 4/8$529
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:16 pm
GSP
-
BOG
2 stops19h 49m
Delta
Wed 8/52:55 pm
BOG
-
GSP
1 stop7h 59m
Delta
Deal found 4/5$535
This BusinessClass deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:38 am
GSP
-
BOG
2 stops16h 47m
LATAM Airlines
Tue 8/42:55 pm
BOG
-
GSP
1 stop17h 18m
LATAM Airlines
Deal found 4/5$537
This LATAM Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:45 am
GSP
-
BOG
2 stops10h 05m
Multiple Airlines
Tue 6/3011:00 am
BOG
-
GSP
2 stops11h 59m
Multiple Airlines
Deal found 4/7$539

Find flight deals from Greenville to South America

Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated April 8, 2026.

Round-trip from

$387
(Kiwi.com)

One-way from

$145
(Trip.com)

Popular in

October

Cheapest in

August

Average price

$883
From Greenville to South America
One-way flight from Greenville to South America
Highest demand for flights based on searches. 8% potential increase in price ($70 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Fri 5/15

5:43 pm-1:03 pm

1 stop20h 20m

Bogotá El Dorado

Sat 6/6

2:08 pm-7:54 pm

1 stop28h 46m

$387

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 7/31

12:06 pm-9:25 pm

1 stop10h 19m

Medellín Jose Maria Cordova Intl

Sun 8/16

10:45 pm-5:39 pm

2 stops17h 54m

$507

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Wed 7/22

5:16 pm-12:05 pm

2 stops19h 49m

Bogotá El Dorado

Wed 8/5

2:55 pm-11:54 pm

1 stop7h 59m

$535

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 9/21

7:51 pm-9:10 pm

2 stops26h 19m

Medellín Jose Maria Cordova Intl

Wed 9/30

9:45 am-9:46 pm

1 stop11h 01m

$545

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 9/21

12:55 pm-8:00 pm

1 stop8h 05m

Medellín Jose Maria Cordova Intl

Mon 9/28

3:05 pm-11:55 am

1 stop19h 50m

$550

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Fri 8/21

5:45 am-7:15 pm

1 stop14h 30m

Bogotá El Dorado

Sat 8/29

2:55 pm-9:27 am

1 stop17h 32m

$555

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Fri 5/29

11:28 am-7:15 pm

1 stop8h 47m

Bogotá El Dorado

Sun 6/7

5:00 am-11:59 pm

2 stops17h 59m

$555

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 9/25

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Tue 9/29

9:45 am-9:46 pm

1 stop11h 01m

$574

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 8/26

6:44 pm-12:50 pm

1 stop19h 06m

Medellín Jose Maria Cordova Intl

Sat 8/29

12:25 am-6:14 pm

1 stop16h 49m

$584

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 5/9

7:00 am-8:15 pm

2 stops14h 15m

Medellín Jose Maria Cordova Intl

Fri 5/22

11:59 pm-2:07 pm

2 stops13h 08m

$585

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/5

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in July is currently the most expensive (average of $354). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 8, 2026.
Read through reviews of airlines operating flights from Greenville to South America, such as Delta,LATAM Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • How long is the flight from Greenville to South America?

    Delta, American Airlines, and United Airlines can get you from Greenville to South America in just under 7h 41m. Your travel time can differ by up to 18h 38m. The distance from Greenville to South America is about 2030 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Greenville to South America?

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in July is currently the most expensive (average of $354). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Greenville to South America

Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$502Average$843FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$535Average$913FlexibilityNo cancel feeOn-time81%
DeltaCheapest$536Average$809FlexibilityNo cancel feeOn-timeN/A

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