In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What is the cheapest time of day to fly from FLO to SA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florence, South Carolina to South America as you normally would.

What airport do you fly from for flights from Florence to South America?

If you book a flight to South America from Florence, you will be flying from Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

Can I find deals for flights from Florence to South America that include hotel bookings?

Yes. In addition to deals on Florence to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florence to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to South America.

Can I find deals for business class flights from Florence to South America?

Yes. Cheapflights offers flight deals from Florence to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$735+ Flights from Florence, SC to South America

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Cheap flight deals from Florence to South America

Round-trip from	$735 (American Airlines)

From Florence to South America

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Cheapest flights from Florence to South America
Explore the most affordable flight options available from Florence to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Sat 10/2511:11 amFLO - CLO

2 stops27h 09mAmerican Airlines

Wed 10/292:20 pmCLO - FLO

2 stops22h 44mAmerican Airlines

Deal found 6/30

$735

Best flights from Florence to South America
Discover carefully curated flight deals from Florence to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Sat 10/2511:11 amFLO - CLO

2 stops27h 09mAmerican Airlines

Wed 10/292:20 pmCLO - FLO

2 stops22h 44mAmerican Airlines

Deal found 6/30

$735

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceCali

FLO - CLO

FLOCLO

Florence

Sat 10/25

2:29 pm-1:20 pm

2 stops23h 51m

Cali Alfonso B. Aragon Intl

Wed 10/29

2:20 pm-10:46 am

2 stops19h 26m

$735

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Florence to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Florence with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to South America

What is the cheapest month to book a flight from Florence, South Carolina to South America?

Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to South America (average of $359). Flying from Florence, South Carolina to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get a feel of what it's like to fly with American Airlines from Florence to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

Related info for your journey

What airport do you fly from for flights from Florence to South America?
If you book a flight to South America from Florence, you will be flying from Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.
Can I find deals for flights from Florence to South America that include hotel bookings?
Yes. In addition to deals on Florence to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florence to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to South America.
Can I find deals for business class flights from Florence to South America?
Yes. Cheapflights offers flight deals from Florence to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florence, South Carolina to South America?
Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to South America (average of $359). Flying from Florence, South Carolina to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$735+ Cheap flights from Florence, SC (FLO) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to South America

Keep the following information in mind while searching for Florence to South America flight deals. Data was last updated July 3, 2025.

Round-trip from

Find flight deals from Florence to South America

Cheapest flights from Florence to South AmericaExplore the most affordable flight options available from Florence to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from Florence to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to South America that are best for you.

Best time to book a flight from Florence to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Florence with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florence to South America

What is the cheapest month to book a flight from Florence, South Carolina to South America?

Reviews of airlines servicing South America

Get a feel of what it's like to fly with American Airlines from Florence to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florence to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Florence to South America?

Can I find deals for flights from Florence to South America that include hotel bookings?

How can I find direct flights from Florence to South America?

Can I find deals for business class flights from Florence to South America?

What is the cheapest month to book a flight from Florence, South Carolina to South America?

Browse thousands of different options on Cheapflights for your next trip

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Cheapest flights from Florence to South America
Explore the most affordable flight options available from Florence to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.