$616+ Cheap flights from Florence, SC (FLO) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — BOG
Mar 14 — Mar 211
1 adult, Economy
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Cheapest flights from Florence to South AmericaExplore the most affordable flight options available from Florence to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from Florence to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:20 pm
FLO
- CLO
2 stops20h 00m
American Airlines
Fri 4/32:20 pm
CLO
- FLO
2 stops26h 30m
American Airlines
Deal found 2/9![American Airlines logo]()
$616
Best flights from Florence to South AmericaDiscover carefully curated flight deals from Florence to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from Florence to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:20 pm
FLO
- CLO
2 stops20h 00m
American Airlines
Fri 4/32:20 pm
CLO
- FLO
2 stops26h 30m
American Airlines
Deal found 2/9![American Airlines logo]()
$616
Last-minute flights from Florence to South AmericaDiscover last-minute flight deals from Florence to South America. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to South America. Data last updated February 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:20 pm
FLO
- CLO
2 stops20h 00m
American Airlines
Fri 4/32:20 pm
CLO
- FLO
2 stops26h 30m
American Airlines
Deal found 2/9![American Airlines logo]()
$616
Find flight deals from Florence to South America
Keep the following information in mind while searching for Florence to South America flight deals. Data was last updated February 12, 2026.
Round-trip from | $616 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Florence to South America that are best for you.
Fly from
Florence
Fly to
South America
Route
Depart
Return
Price
FlorenceCali
FLO - CLO
FLOCLO
Florence
Fri 3/27
6:20 pm-1:20 pm
2 stops20h 00m
Cali Alfonso B. Aragon Intl
Fri 4/3
2:20 pm-5:50 pm
2 stops26h 30m
$616
Best time to book a flight from Florence to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Florence with our price prediction graph.
FLO-CLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to South America
FLO-0SA
FLO-CLO
What is the cheapest month to book a flight from Florence, South Carolina to South America?
Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to South America (average of $96). Flying from Florence, South Carolina to South America in June is currently the most expensive (average of $444). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Florence to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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