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South America

$150+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Expedia deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:33 pmCMH - CTG
1 stop16h 37mSpirit Airlines
Mon 12/152:15 pmCTG - CMH
1 stop7h 59mSpirit Airlines
Deal found 11/17$355
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2912:14 pmCMH - MDE
2 stops36h 42mMultiple Airlines
Fri 12/52:05 amMDE - CMH
1 stop20h 09mMultiple Airlines
Deal found 11/16$425
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:06 pmCMH - BOG
1 stop16h 54mMultiple Airlines
Fri 12/52:17 amBOG - CMH
1 stop19h 57mMultiple Airlines
Deal found 11/15$431
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amCMH - MDE
1 stop18h 56mSpirit Airlines
Fri 12/52:05 amMDE - CMH
1 stop20h 09mSpirit Airlines
Deal found 11/16$437
This KAYAK deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:28 pmCMH - BOG
1 stop18h 24mSpirit Airlines
Sun 12/283:05 pmBOG - CMH
1 stop26h 28mSpirit Airlines
Deal found 11/16$459
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:14 amCMH - BOG
1 stop26h 55mSpirit Airlines
Sun 12/282:17 amBOG - CMH
1 stop15h 16mSpirit Airlines
Deal found 11/15$463
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:33 pmCMH - GYE
1 stop27h 10mSpirit Airlines
Sun 12/1412:49 amGYE - CMH
1 stop21h 25mSpirit Airlines
Deal found 11/16$464
This KAYAK deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:14 amCMH - BOG
1 stop13h 58mSpirit Airlines
Wed 12/242:17 amBOG - CMH
1 stop15h 16mSpirit Airlines
Deal found 11/16$471
This KAYAK deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:33 pmCMH - CTG
1 stop16h 37mSpirit Airlines
Tue 12/162:15 pmCTG - CMH
2 stops20h 04mSpirit Airlines
Deal found 11/16$474
This Mytrip deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:14 amCMH - MDE
2 stops13h 55mSpirit Airlines
Tue 12/911:50 amMDE - CMH
1 stop7h 48mSpirit Airlines
Deal found 11/15$481
This KAYAK deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:28 pmCMH - BOG
1 stop18h 24mSpirit Airlines
Mon 12/292:17 amBOG - CMH
1 stop15h 16mSpirit Airlines
Deal found 11/16$485
This Mytrip deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:14 amCMH - CTG
3 stops20h 45mMultiple Airlines
Mon 12/152:15 pmCTG - CMH
2 stops20h 04mMultiple Airlines
Deal found 11/17$487

Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated November 17, 2025.

Round-trip from

$311
(Orbitz)

One-way from

$150
(Kiwi.com)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Wed 2/18

5:40 am-12:47 pm

1 stop7h 07m

Bogotá El Dorado

Mon 2/23

1:47 pm-11:53 pm

1 stop10h 06m

$306

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Wed 2/11

6:15 am-12:21 am

1 stop18h 06m

Guayaquil Jose Joaquin de Olmedo

Sat 2/21

12:59 am-9:40 am

1 stop8h 41m

$311

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sat 2/21

6:15 am-1:13 pm

1 stop6h 58m

Cartagena Rafael Nunez

Sun 3/1

2:21 pm-10:13 pm

1 stop7h 52m

$325

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Sun 2/22

5:40 am-12:47 pm

1 stop7h 07m

Bogotá El Dorado

Tue 3/3

1:47 pm-11:53 pm

1 stop10h 06m

$326

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 1/6

11:14 am-1:28 am

1 stop14h 14m

Medellín Jose Maria Cordova Intl

Wed 1/28

2:50 pm-11:58 pm

1 stop9h 08m

$335

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sun 12/7

8:33 pm-1:10 pm

1 stop16h 37m

Cartagena Rafael Nunez

Mon 12/15

2:15 pm-10:14 pm

1 stop7h 59m

$355

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 2/18

5:40 am-1:59 pm

1 stop8h 19m

Medellín Jose Maria Cordova Intl

Mon 2/23

2:54 pm-11:53 pm

1 stop8h 59m

$368

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 1/21

6:15 am-9:40 pm

1 stop15h 25m

Medellín Jose Maria Cordova Intl

Mon 1/26

1:00 pm-10:13 pm

1 stop9h 13m

$403

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Tue 3/10

5:40 am-11:47 am

1 stop7h 07m

Bogotá El Dorado

Wed 3/11

12:47 pm-11:53 pm

1 stop10h 06m

$409

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 3/18

5:15 am-9:40 pm

1 stop17h 25m

Medellín Jose Maria Cordova Intl

Sun 3/22

1:00 pm-9:40 am

1 stop19h 40m

$422

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

It’s typically best to fly out from Columbus to South America in the evening. Doing so could potentially save you 14% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Columbus to South America?

Use this chart to determine the cheapest time to fly round-trip from Columbus to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Columbus to South America flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 17, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,006 reviews

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,006 reviews
Delta
7.9
Good
8,006 reviews

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,877 reviews
Delta
7.9
Good
8,006 reviews

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,014 reviews
Delta
7.9
Good
8,006 reviews

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
8,006 reviews

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,144 reviews
Delta
7.9
Good
8,006 reviews

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $306, Spirit Airlines can have you in South America from Columbus in 7h 07m. There are 2497 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Columbus to South America one-way?

    One-way options have recently been found by users for as low as $154 on Spirit Airlines. Other airlines that offer cheap prices include Copa Airlines from $277 and Air Canada from $420 one-way.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Buenos Aires Ministro Pistarini, Columbus - Sao Paulo Guarulhos Intl or Columbus - Medellín Jose Maria Cordova Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$430FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$490Average$713FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$534Average$1,064FlexibilityNo cancel feeOn-time69%
DeltaCheapest$552Average$931FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$555Average$826FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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