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South America

$98+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Feb 10 — Feb 171
Tue 2/10
Tue 2/17
1 adult, Economy
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Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated January 11, 2026.

Round-trip from

$242
(Expedia)

One-way from

$98
(Spirit)
From Columbus to South America
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One-way flight from Columbus to South America
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Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 11, 2026.

This Expedia deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/95:45 amCMH - CTG
1 stop7h 25mSpirit Airlines
Wed 2/252:21 pmCTG - CMH
1 stop9h 11mSpirit Airlines
Deal found 1/9$242
This Orbitz deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:15 amCMH - CTG
1 stop6h 55mSpirit Airlines
Thu 2/192:21 pmCTG - CMH
1 stop9h 11mSpirit Airlines
Deal found 1/9$264
This Orbitz deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:15 amCMH - CTG
1 stop7h 50mSpirit Airlines
Thu 4/161:21 pmCTG - CMH
1 stop7h 52mSpirit Airlines
Deal found 1/9$279
This Spirit deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:15 amCMH - MDE
1 stop7h 58mSpirit Airlines
Wed 2/253:15 pmMDE - CMH
1 stop8h 17mSpirit Airlines
Deal found 1/9$282
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2811:39 amCMH - CTG
1 stop25h 31mSpirit Airlines
Wed 3/42:21 pmCTG - CMH
1 stop9h 11mSpirit Airlines
Deal found 1/10$287
This Cheapflightsfares deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/95:45 amCMH - BOG
1 stop8h 22mSpirit Airlines
Mon 2/231:45 pmBOG - CMH
1 stop10h 08mSpirit Airlines
Deal found 1/10$304
This Expedia deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:45 amCMH - LIM
1 stop16h 50mSpirit Airlines
Fri 2/611:33 pmLIM - CMH
1 stop10h 07mSpirit Airlines
Deal found 1/10$307
This Kiwi.com deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:39 amCMH - MDE
1 stop26h 34mSpirit Airlines
Thu 2/263:15 pmMDE - CMH
1 stop8h 17mSpirit Airlines
Deal found 1/9$309
This KAYAK deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:45 amCMH - MDE
1 stop8h 30mSpirit Airlines
Tue 2/173:15 pmMDE - CMH
1 stop19h 29mSpirit Airlines
Deal found 1/9$323
This FlightHub deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/75:45 amCMH - CTG
1 stop7h 25mSpirit Airlines
Sat 2/142:21 pmCTG - CMH
1 stop9h 11mSpirit Airlines
Deal found 1/11$337
This KAYAK deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:39 amCMH - CTG
1 stop25h 31mSpirit Airlines
Mon 3/22:21 pmCTG - CMH
1 stop20h 23mSpirit Airlines
Deal found 1/8$340
This Kiwi.com deal was found by Cheapflights users on 1/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:15 amCMH - MDE
1 stop7h 58mSpirit Airlines
Thu 2/263:15 pmMDE - CMH
1 stop8h 17mSpirit Airlines
Deal found 1/9$341

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 11, 2026.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Mon 4/13

5:15 am-12:05 pm

1 stop7h 50m

Cartagena Rafael Nunez

Thu 4/16

1:21 pm-10:13 pm

1 stop7h 52m

$279

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 2/18

6:15 am-2:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Wed 2/25

3:15 pm-11:32 pm

1 stop8h 17m

$282

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Mon 2/9

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

Mon 2/23

1:45 pm-11:53 pm

1 stop10h 08m

$304

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sat 2/28

1:20 pm-1:10 pm

2 stops23h 50m

Cartagena Rafael Nunez

Wed 3/4

2:21 pm-11:32 pm

1 stop9h 11m

$320

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 2/10

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Tue 2/17

3:15 pm-10:44 am

1 stop19h 29m

$323

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 2/17

6:15 am-2:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Fri 2/27

3:15 pm-10:44 am

1 stop19h 29m

$341

ColumbusLima

CMH - LIM

CMHLIM

Columbus

Mon 2/2

10:40 am-10:35 pm

1 stop11h 55m

Lima J Chavez Intl

Fri 2/6

11:33 pm-11:19 pm

2 stops23h 46m

$345

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Sat 2/7

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Sat 2/14

2:50 pm-11:53 pm

1 stop9h 03m

$365

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Mon 2/9

5:45 am-8:15 pm

2 stops14h 30m

Bogotá El Dorado

Mon 2/23

1:45 pm-10:44 am

2 stops20h 59m

$366

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 2/18

5:45 am-7:27 pm

2 stops13h 42m

Medellín Jose Maria Cordova Intl

Tue 2/24

3:15 pm-11:32 pm

1 stop8h 17m

$368

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, August is the cheapest month in which you can book a flight from Columbus to South America (average of $260). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 11, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,034 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,034 reviews
Delta
7.9
Good
8,034 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,901 reviews
Delta
7.9
Good
8,034 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,101 reviews
Delta
7.9
Good
8,034 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,613 reviews
Delta
7.9
Good
8,034 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,295 reviews
Delta
7.9
Good
8,034 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $279, Spirit Airlines can have you in South America from Columbus in 7h 50m. There are 2090 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Medellín Jose Maria Cordova Intl, Columbus - Santiago Arturo Merino Benitez or Columbus - Lima J Chavez Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, August is the cheapest month in which you can book a flight from Columbus to South America (average of $260). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Columbus to South America

Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$265Average$378FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$443Average$740FlexibilityNo cancel feeOn-time71%
DeltaCheapest$552Average$864FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$555Average$798FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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