HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$136+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbus to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:25 amCMH - CTG
1 stop7h 50mSpirit Airlines
Thu 11/132:20 pmCTG - CMH
1 stop8h 50mSpirit Airlines
Deal found 10/25$276
This KAYAK deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:33 pmCMH - MDE
1 stop28h 36mSpirit Airlines
Wed 12/242:25 amMDE - CMH
1 stop15h 08mSpirit Airlines
Deal found 10/25$295
This Cheapflightsfares deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:25 amCMH - BOG
1 stop8h 45mSpirit Airlines
Thu 11/133:15 pmBOG - CMH
1 stop7h 55mSpirit Airlines
Deal found 10/25$311
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:33 pmCMH - MDE
1 stop28h 36mMultiple Airlines
Thu 12/253:10 pmMDE - CMH
2 stops25h 30mMultiple Airlines
Deal found 10/25$315
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:25 amCMH - MDE
1 stop19h 32mSpirit Airlines
Thu 11/203:14 pmMDE - CMH
1 stop8h 37mSpirit Airlines
Deal found 10/26$319
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:25 amCMH - BOG
1 stop8h 45mSpirit Airlines
Tue 11/253:17 pmBOG - CMH
1 stop8h 34mSpirit Airlines
Deal found 10/27$320
This Orbitz deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:25 amCMH - CTG
1 stop7h 50mSpirit Airlines
Wed 11/122:20 pmCTG - CMH
1 stop8h 50mSpirit Airlines
Deal found 10/25$321
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:25 amCMH - BOG
1 stop8h 45mSpirit Airlines
Mon 11/243:17 pmBOG - CMH
1 stop8h 34mSpirit Airlines
Deal found 10/27$325
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:25 amCMH - MDE
1 stop8h 38mSpirit Airlines
Fri 11/213:14 pmMDE - CMH
1 stop8h 37mSpirit Airlines
Deal found 10/25$349
This KAYAK deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:33 pmCMH - MDE
1 stop28h 36mSpirit Airlines
Mon 12/811:50 amMDE - CMH
1 stop7h 48mSpirit Airlines
Deal found 10/25$356
This Avianca Connect deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:25 amCMH - MDE
1 stop16h 15mMultiple Airlines
Tue 11/181:00 pmMDE - CMH
1 stop10h 10mMultiple Airlines
Deal found 10/25$359
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
Sun 12/72:15 pmCTG - CMH
1 stop7h 59mSpirit Airlines
Deal found 10/25$391

Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated October 27, 2025.

Round-trip from

$276
(CheapOair)

One-way from

$136
(Cheapflightsfares)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sun 11/9

5:25 am-1:15 pm

1 stop7h 50m

Cartagena Rafael Nunez

Thu 11/13

2:20 pm-11:10 pm

1 stop8h 50m

$301

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Mon 11/10

5:25 am-2:10 pm

1 stop8h 45m

Bogotá El Dorado

Thu 11/13

3:15 pm-11:10 pm

1 stop7h 55m

$311

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Sun 12/7

8:33 pm-1:09 am

1 stop28h 36m

Medellín Jose Maria Cordova Intl

Thu 12/25

3:10 pm-4:40 pm

2 stops25h 30m

$315

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Mon 11/10

5:25 am-2:10 pm

1 stop8h 45m

Bogotá El Dorado

Tue 11/25

3:17 pm-11:51 pm

1 stop8h 34m

$320

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Mon 11/10

5:25 am-9:40 pm

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 11/18

1:00 pm-11:10 pm

1 stop10h 10m

$359

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 2/11

6:45 am-1:08 pm

1 stop6h 23m

Cartagena Rafael Nunez

Tue 2/17

2:16 pm-9:55 am

1 stop19h 39m

$359

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Sun 2/1

9:10 pm-1:02 pm

1 stop15h 52m

Bogotá El Dorado

Sat 2/7

1:57 pm-8:15 am

1 stop18h 18m

$371

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Sun 2/1

9:10 pm-1:02 pm

1 stop15h 52m

Bogotá El Dorado

Sun 2/8

1:57 pm-8:15 am

1 stop18h 18m

$371

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Sun 11/16

9:42 am-12:57 am

2 stops15h 15m

Medellín Jose Maria Cordova Intl

Thu 11/20

3:14 pm-2:13 pm

2 stops22h 59m

$375

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 11/13

5:25 am-2:03 pm

1 stop8h 38m

Medellín Jose Maria Cordova Intl

Fri 11/21

3:14 pm-11:51 pm

1 stop8h 37m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

It’s typically best to fly out from Columbus to South America in the evening. Doing so could potentially save you 14% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Columbus to South America?

Use this chart to determine the cheapest time to fly round-trip from Columbus to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Columbus to South America flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 27, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,995 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,995 reviews
Delta
7.9
Good
7,995 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,872 reviews
Delta
7.9
Good
7,995 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
7,995 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,031 reviews
Delta
7.9
Good
7,995 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,111 reviews
Delta
7.9
Good
7,995 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $301, Spirit Airlines can have you in South America from Columbus in 7h 50m. There are 2090 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Medellín Jose Maria Cordova Intl, Columbus - Buenos Aires Ministro Pistarini or Columbus - Sao Paulo Guarulhos Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbus to South America

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Cancún flights
Detroit to Orlando flights
Cleveland to Orlando flights
Detroit to John F Kennedy Intl flights
Cleveland to Las Vegas flights
Detroit to Las Vegas flights
Detroit to Fort Lauderdale flights
Cleveland to John F Kennedy Intl flights
Cincinnati to LaGuardia flights
Detroit to Los Angeles flights
Cincinnati to Orlando flights
Detroit to Sky Harbor Intl flights
Cleveland to LaGuardia flights
Detroit to Miami flights
Detroit to Dallas/Fort Worth flights
Cleveland to Fort Lauderdale flights
Cincinnati to John F Kennedy Intl flights
Detroit to LaGuardia flights
Detroit to Newark flights
Cleveland to Fort Myers flights
Cincinnati to Las Vegas flights
Columbus to John F Kennedy Intl flights
Cincinnati to Fort Lauderdale flights
Cleveland to Cancún flights
Cincinnati to Newark flights
Cleveland to Newark flights
Detroit to Denver flights
Columbus to Newark flights
Pittsburgh to John F Kennedy Intl flights
Akron to Orlando flights
Columbus to LaGuardia flights
Cleveland to Sky Harbor Intl flights
Cincinnati to Miami flights
Detroit to Baltimore flights
Detroit to Fort Myers flights
Detroit to Tampa flights
Cleveland to Tampa flights
Cincinnati to Denver flights
Cincinnati to Dallas/Fort Worth flights
Detroit to Dulles Intl flights
Pittsburgh to Orlando flights
Pittsburgh to LaGuardia flights
Pittsburgh to Fort Lauderdale flights
Detroit to Luis Munoz Marin Intl flights
Detroit to Hobby flights
Detroit to Reagan-National flights
Detroit to San Francisco flights
Cleveland to Atlanta flights
Pittsburgh to Las Vegas flights
Columbus to Las Vegas flights

Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$427FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$490Average$713FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$534Average$960FlexibilityNo cancel feeOn-time69%
DeltaCheapest$552Average$853FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$555Average$821FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.