South America

$129+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Feb 1 — Feb 81
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Cheap flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:14 amCHS - MDE
2 stops13h 56mAmerican Airlines
Mon 1/57:00 amMDE - CHS
1 stop17h 45mAmerican Airlines
Deal found 12/30$1,133
This United Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:59 pmCHS - MDE
2 stops29h 06mUnited Airlines
Mon 1/510:45 amMDE - CHS
2 stops27h 17mUnited Airlines
Deal found 12/30$1,182
This Mytrip deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:15 pmCHS - MDE
2 stops19h 05mMultiple Airlines
Mon 1/56:45 amMDE - CHS
3 stops30h 25mMultiple Airlines
Deal found 12/30$1,331

Find flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated January 2, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$273
(Kiwi.com)

One-way from

$129
(Kiwi.com)
Provider with most accurate pricing for Charleston-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Charleston-Sao Paulo (SAO) flights.
From Charleston to South America
One-way flight from Charleston to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 2, 2026.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 1/23

6:35 pm-12:21 am

1 stop29h 46m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

1:26 am-5:36 pm

1 stop16h 10m

$273

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sun 1/25

6:35 pm-12:21 am

1 stop29h 46m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

1:26 am-5:36 pm

1 stop16h 10m

$280

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 1/23

6:35 pm-12:21 am

1 stop29h 46m

Guayaquil Jose Joaquin de Olmedo

Sat 1/31

6:55 pm-5:39 pm

2 stops22h 44m

$297

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Tue 3/10

11:47 am-1:50 am

2 stops15h 03m

Bogotá El Dorado

Wed 3/18

7:05 am-8:03 pm

1 stop11h 58m

$376

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sun 2/15

6:35 pm-12:04 am

1 stop29h 29m

Guayaquil Jose Joaquin de Olmedo

Sat 2/21

8:34 am-5:40 pm

2 stops33h 06m

$379

CharlestonLima

CHS - LIM

CHSLIM

Charleston

Mon 2/2

6:35 pm-10:35 pm

1 stop28h 00m

Lima J Chavez Intl

Thu 2/5

11:33 pm-4:10 pm

2 stops16h 37m

$382

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Fri 3/20

9:22 am-8:25 pm

1 stop12h 03m

Bogotá El Dorado

Wed 3/25

7:05 am-8:03 pm

1 stop11h 58m

$399

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Sat 2/21

6:35 pm-2:10 pm

1 stop19h 35m

Bogotá El Dorado

Sat 3/14

2:05 pm-11:26 pm

1 stop8h 21m

$412

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Wed 3/18

7:00 am-6:10 pm

1 stop12h 10m

Bogotá El Dorado

Sun 3/22

9:15 am-11:26 pm

1 stop13h 11m

$416

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Sat 2/21

6:35 pm-2:10 pm

1 stop19h 35m

Bogotá El Dorado

Sat 3/14

3:55 pm-4:07 pm

2 stops23h 12m

$431

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/31

Showing 1-10 of 55 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, November is the cheapest month in which you can book a flight from Charleston to South America (average of $113). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 2, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like Spirit Airlines, American Airlines, and LATAM Airlines fly from Charleston to South America in about 10h 04m. The time it takes to get you to your destination can typically vary by up to 19h 42m. Charleston and South America are separated by a distance of 1869 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charleston to South America?

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, November is the cheapest month in which you can book a flight from Charleston to South America (average of $113). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charleston to South America

Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$301Average$893FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$435Average$782FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$542Average$732FlexibilityNo cancel feeOn-time81%

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