$192+ Cheap flights from Charleston (CHS) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Aug 6 — Aug 131
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to South America with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to South America
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Cheapest flights from Charleston to South AmericaExplore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:05 am
CHS
- UIO
2 stops15h 10m
Multiple Airlines
Sat 10/245:25 pm
UIO
- CHS
1 stop15h 34m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$454
This Jetabroad deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:27 pm
CHS
- CTG
1 stop19h 08m
JetBlue
Thu 8/2712:35 pm
CTG
- CHS
1 stop27h 31m
JetBlue
Deal found 7/6![JetBlue logo]()
$487
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:13 pm
CHS
- GYE
1 stop18h 12m
American Airlines
Sun 7/262:25 pm
GYE
- CHS
1 stop18h 57m
American Airlines
Deal found 7/2![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
CHS
- CTG
1 stop8h 15m
American Airlines
Tue 8/251:35 pm
CTG
- CHS
1 stop8h 23m
American Airlines
Deal found 7/4![American Airlines logo]()
$521
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:10 am
CHS
- CTG
1 stop9h 05m
Delta
Tue 8/252:30 pm
CTG
- CHS
1 stop8h 29m
Delta
Deal found 7/4![Delta logo]()
$523
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:58 pm
CHS
- BOG
1 stop13h 32m
Multiple Airlines
Mon 10/127:10 am
BOG
- CHS
1 stop11h 20m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$527
This Despegar deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:27 pm
CHS
- CTG
1 stop19h 08m
JetBlue
Wed 8/2612:35 pm
CTG
- CHS
1 stop26h 58m
JetBlue
Deal found 7/4![JetBlue logo]()
$531
This KAYAK deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:25 pm
CHS
- CTG
1 stop18h 27m
JetBlue
Sat 9/192:00 pm
CTG
- CHS
1 stop27h 30m
JetBlue
Deal found 7/3![JetBlue logo]()
$540
This Avianca deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:58 pm
CHS
- BOG
1 stop13h 32m
Multiple Airlines
Mon 10/267:05 am
BOG
- CHS
1 stop11h 20m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$541
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:48 pm
CHS
- CTG
2 stops17h 47m
American Airlines
Thu 8/273:15 pm
CTG
- CHS
1 stop7h 44m
American Airlines
Deal found 7/6![American Airlines logo]()
$548
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:04 pm
CHS
- BOG
1 stop11h 41m
Multiple Airlines
Wed 9/94:05 pm
BOG
- CHS
1 stop15h 33m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$554
This Avianca deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:38 pm
CHS
- BOG
1 stop13h 52m
Multiple Airlines
Sat 9/129:05 am
BOG
- CHS
1 stop8h 25m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$556
Best flights from Charleston to South AmericaDiscover carefully curated flight deals from Charleston to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
Discover carefully curated flight deals from Charleston to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:13 pm
CHS
- GYE
1 stop18h 12m
American Airlines
Sun 7/262:25 pm
GYE
- CHS
1 stop18h 57m
American Airlines
Deal found 7/2![American Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:10 am
CHS
- CTG
1 stop9h 05m
Delta
Tue 8/252:30 pm
CTG
- CHS
1 stop8h 29m
Delta
Deal found 7/4![Delta logo]()
$523
This Avianca deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:50 pm
CHS
- BOG
1 stop11h 40m
Multiple Airlines
Sun 10/117:10 am
BOG
- CHS
1 stop11h 20m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$527
This KAYAK deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:50 pm
CHS
- GYE
2 stops27h 47m
GOL
Sun 7/262:25 pm
GYE
- CHS
2 stops21h 04m
GOL
Deal found 7/2![GOL logo]()
$568
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:00 am
CHS
- BOG
1 stop16h 00m
United Airlines
Wed 8/268:30 am
BOG
- CHS
1 stop12h 41m
United Airlines
Deal found 7/2![United Airlines logo]()
$605
This LATAM Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:55 am
CHS
- UIO
1 stop12h 04m
LATAM Airlines
Wed 9/2312:59 am
UIO
- CHS
1 stop15h 47m
LATAM Airlines
Deal found 7/5![LATAM Airlines logo]()
$705
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
CHS
- CTG
1 stop8h 15m
American Airlines
Tue 8/251:35 pm
CTG
- CHS
1 stop8h 23m
American Airlines
Deal found 7/4![American Airlines logo]()
$521
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:10 am
CHS
- CTG
1 stop9h 05m
Delta
Thu 8/272:30 pm
CTG
- CHS
1 stop8h 29m
Delta
Deal found 7/5![Delta logo]()
$523
This Avianca deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:58 pm
CHS
- BOG
1 stop13h 32m
Multiple Airlines
Mon 10/267:05 am
BOG
- CHS
1 stop11h 20m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$541
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:10 am
CHS
- BOG
1 stop11h 50m
United Airlines
Tue 9/158:30 am
BOG
- CHS
1 stop12h 41m
United Airlines
Deal found 7/6![United Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:10 am
CHS
- CTG
1 stop6h 05m
Delta
Sun 8/304:30 am
CTG
- CHS
2 stops18h 29m
Delta
Deal found 7/3![Delta logo]()
$557
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
CHS
- CTG
1 stop9h 15m
American Airlines
Thu 8/273:15 pm
CTG
- CHS
2 stops20h 12m
American Airlines
Deal found 7/5![American Airlines logo]()
$558
This KAYAK deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
CHS
- EZE
2 stops16h 51m
Copa Airlines
Tue 8/255:25 am
EZE
- CHS
2 stops30h 11m
Copa Airlines
Deal found 7/6![Copa Airlines logo]()
$1,244
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:59 pm
CHS
- CTG
1 stop18h 06m
Delta
Tue 11/245:00 am
CTG
- CHS
2 stops11h 51m
Delta
Deal found 7/5![Delta logo]()
$558
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am
CHS
- CTG
1 stop9h 14m
American Airlines
Tue 11/242:34 pm
CTG
- CHS
2 stops17h 55m
American Airlines
Deal found 7/5![American Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:45 am
CHS
- MDE
1 stop15h 25m
United Airlines
Sun 11/810:40 am
MDE
- CHS
1 stop11h 15m
United Airlines
Deal found 7/3![United Airlines logo]()
$631
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:14 pm
CHS
- MDE
2 stops13h 31m
Multiple Airlines
Sun 8/3010:40 pm
MDE
- CHS
1 stop10h 28m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$645
This oojo deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:25 pm
CHS
- LIM
1 stop13h 35m
LATAM Airlines
Tue 9/2212:15 am
LIM
- CHS
2 stops17h 56m
LATAM Airlines
Deal found 7/2![LATAM Airlines logo]()
$723
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:10 am
CHS
- BOG
1 stop9h 30m
Delta
Mon 9/142:55 pm
BOG
- CHS
1 stop8h 02m
Delta
Deal found 7/3![Delta logo]()
$585
This Avianca deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:14 pm
CHS
- MDE
1 stop10h 11m
Multiple Airlines
Mon 8/317:40 pm
MDE
- CHS
2 stops13h 23m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$647
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:59 pm
CHS
- CTG
1 stop19h 15m
American Airlines
Mon 11/94:15 pm
CTG
- CHS
2 stops18h 32m
American Airlines
Deal found 7/6![American Airlines logo]()
$598
This LATAM Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:20 pm
CHS
- LIM
1 stop13h 40m
LATAM Airlines
Sat 10/319:00 am
LIM
- CHS
2 stops23h 44m
LATAM Airlines
Deal found 7/3![LATAM Airlines logo]()
$749
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am
CHS
- BOG
2 stops12h 35m
Delta
Mon 9/1411:00 am
BOG
- CHS
2 stops11h 57m
Delta
Deal found 7/3![Delta logo]()
$590
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
CHS
- BOG
1 stop16h 17m
American Airlines
Mon 10/126:30 am
BOG
- CHS
1 stop10h 57m
American Airlines
Deal found 7/4![American Airlines logo]()
$609
This oojo deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:59 pm
CHS
- LIM
2 stops23h 26m
LATAM Airlines
Mon 11/308:40 pm
LIM
- CHS
2 stops20h 11m
LATAM Airlines
Deal found 7/6![LATAM Airlines logo]()
$749
This FlightHub deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
CHS
- GRU
2 stops33h 20m
GOL
Thu 8/136:00 am
GRU
- CHS
2 stops18h 59m
GOL
Deal found 7/5![GOL logo]()
$919
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:10 am
CHS
- BOG
2 stops13h 00m
Delta
Wed 9/911:00 am
BOG
- CHS
2 stops11h 57m
Delta
Deal found 7/3![Delta logo]()
$590
This Avianca deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:58 am
CHS
- GYE
1 stop21h 47m
Multiple Airlines
Tue 8/114:05 pm
GYE
- CHS
1 stop17h 03m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$725
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am
CHS
- MDE
2 stops15h 15m
American Airlines
Sun 10/256:00 am
MDE
- CHS
1 stop11h 27m
American Airlines
Deal found 7/6![American Airlines logo]()
$612
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
CHS
- UIO
2 stops48h 00m
United Airlines
Fri 7/3112:35 am
UIO
- CHS
2 stops44h 13m
United Airlines
Deal found 7/3![United Airlines logo]()
$883
Last-minute flights from Charleston to South AmericaDiscover last-minute flight deals from Charleston to South America. Data last updated July 7, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to South America. Data last updated July 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:13 pm
CHS
- GYE
1 stop18h 12m
American Airlines
Sun 7/262:25 pm
GYE
- CHS
1 stop18h 57m
American Airlines
Deal found 7/2![American Airlines logo]()
$518
This KAYAK deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:50 pm
CHS
- GYE
2 stops27h 47m
GOL
Sun 7/262:25 pm
GYE
- CHS
2 stops21h 04m
GOL
Deal found 7/2![GOL logo]()
$568
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
CHS
- CTG
1 stop8h 15m
American Airlines
Tue 8/251:35 pm
CTG
- CHS
1 stop8h 23m
American Airlines
Deal found 7/4![American Airlines logo]()
$521
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:10 am
CHS
- CTG
1 stop9h 05m
Delta
Tue 8/252:30 pm
CTG
- CHS
1 stop8h 29m
Delta
Deal found 7/4![Delta logo]()
$523
This Despegar deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:27 pm
CHS
- CTG
1 stop19h 08m
JetBlue
Wed 8/2612:35 pm
CTG
- CHS
1 stop26h 58m
JetBlue
Deal found 7/4![JetBlue logo]()
$531
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:48 pm
CHS
- CTG
2 stops19h 27m
American Airlines
Wed 8/263:15 pm
CTG
- CHS
2 stops17h 24m
American Airlines
Deal found 7/4![American Airlines logo]()
$559
This Jetabroad deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:27 pm
CHS
- CTG
1 stop19h 08m
JetBlue
Thu 8/2712:35 pm
CTG
- CHS
1 stop27h 31m
JetBlue
Deal found 7/6![JetBlue logo]()
$487
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:48 pm
CHS
- CTG
2 stops17h 47m
American Airlines
Thu 8/273:15 pm
CTG
- CHS
1 stop7h 44m
American Airlines
Deal found 7/6![American Airlines logo]()
$548
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:10 am
CHS
- CTG
1 stop6h 05m
Delta
Sun 8/304:30 am
CTG
- CHS
2 stops18h 29m
Delta
Deal found 7/3![Delta logo]()
$557
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:11 pm
CHS
- BOG
1 stop18h 29m
Delta
Mon 9/142:55 pm
BOG
- CHS
1 stop18h 11m
Delta
Deal found 7/3![Delta logo]()
$592
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:15 am
CHS
- BOG
1 stop8h 25m
Delta
Mon 9/142:55 pm
BOG
- CHS
1 stop16h 51m
Delta
Deal found 7/3![Delta logo]()
$585
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:10 am
CHS
- BOG
2 stops13h 00m
Delta
Wed 9/911:00 am
BOG
- CHS
2 stops11h 57m
Delta
Deal found 7/3![Delta logo]()
$590
One-way flights from Charleston to South AmericaSearch for one-way flight options from Charleston to South America. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
Search for one-way flight options from Charleston to South America. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
This Avianca deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:47 pm
CHS
- GYE
1 stop14h 53m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$192
This Avianca deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:58 am
CHS
- GYE
1 stop21h 47m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:44 pm
CHS
- MDE
3 stops59h 31m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$220
This Expedia deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:59 pm
CHS
- CTG
1 stop18h 36m
JetBlue
Deal found 7/6![JetBlue logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:04 pm
CHS
- BOG
3 stops29h 16m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:13 pm
CHS
- BOG
2 stops29h 57m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$254
This oojo deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:14 pm
CHS
- UIO
2 stops17h 51m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:50 pm
CHS
- CTG
2 stops19h 27m
American Airlines
Deal found 7/2![American Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:04 pm
CHS
- BOG
2 stops26h 03m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:56 pm
CHS
- MDE
3 stops47h 44m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$273
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1210:58 am
CHS
- GYE
1 stop21h 47m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:53 pm
CHS
- BOG
2 stops30h 17m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$282
Find flight deals from Charleston to South America
Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated July 7, 2026.
Round-trip from | $454 (Avianca) |
|---|---|
One-way from | $192 (Avianca) |
Popular in | April |
Cheapest in | September |
Average price | $863 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
Use the filters below to find and compare flights from Charleston to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGuayaquil
CHS - GYE
CHSGYE
Charleston
Thu 7/23
8:13 pm-1:25 pm
1 stop18h 12m
Guayaquil Jose Joaquin de Olmedo
Sun 7/26
2:25 pm-10:22 am
1 stop18h 57m
$518
Quickest round-trip
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Tue 8/18
7:00 am-2:15 pm
1 stop8h 15m
Cartagena Rafael Nunez
Tue 8/25
1:35 pm-10:58 pm
1 stop8h 23m
$521
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Tue 8/18
5:10 am-1:15 pm
1 stop9h 05m
Cartagena Rafael Nunez
Tue 8/25
2:30 pm-11:59 pm
1 stop8h 29m
$523
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Thu 8/20
5:10 am-1:15 pm
1 stop9h 05m
Cartagena Rafael Nunez
Thu 8/27
2:30 pm-11:59 pm
1 stop8h 29m
$523
CharlestonBogotá
CHS - BOG
CHSBOG
Charleston
Thu 10/1
6:50 pm-5:30 am
1 stop11h 40m
Bogotá El Dorado
Sun 10/11
7:10 am-7:30 pm
1 stop11h 20m
$527
CharlestonBogotá
CHS - BOG
CHSBOG
Charleston
Sat 10/17
4:58 pm-5:30 am
1 stop13h 32m
Bogotá El Dorado
Mon 10/26
7:05 am-7:25 pm
1 stop11h 20m
$541
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Tue 8/25
8:10 am-1:15 pm
1 stop6h 05m
Cartagena Rafael Nunez
Sun 8/30
4:30 am-11:59 pm
2 stops18h 29m
$557
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Thu 8/20
6:00 am-2:15 pm
1 stop9h 15m
Cartagena Rafael Nunez
Thu 8/27
3:15 pm-12:27 pm
2 stops20h 12m
$558
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Tue 11/10
7:59 pm-2:05 pm
1 stop18h 06m
Cartagena Rafael Nunez
Tue 11/24
5:00 am-4:51 pm
2 stops11h 51m
$558
CharlestonGuayaquil
CHS - GYE
CHSGYE
Charleston
Thu 7/23
7:50 pm-10:37 pm
2 stops27h 47m
Guayaquil Jose Joaquin de Olmedo
Sun 7/26
2:25 pm-12:29 pm
2 stops21h 04m
$568
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Charleston to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
CHS-GYE
CHS-CTG
CHS-BOG
CHS-UIO
CHS-EZE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to South America
CHS-0SA
CHS-GYE
CHS-CTG
CHS-BOG
CHS-UIO
What is the cheapest month to book a flight from Charleston to South America?
Currently, September is the cheapest month in which you can book a flight from Charleston to South America (average of $156). Flying from Charleston to South America in May is currently the most expensive (average of $699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 7, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andAmerican Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to South America by cabin class
Find flights from Charleston to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and South America flights
Browse other Charleston and South America flight options. Last updated on July 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Charleston to South America flights
Consider these flights traveling from Charleston to South America.
Top 3 airlines flying from Charleston to South America
Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$301 | Average$659 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$523 | Average$952 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$542 | Average$732 | FlexibilityNo cancel fee | On-time81% |