South America

$243+ Cheap flights from Charleston (CHS) to South America

CHS — BOG
Dec 4 — Dec 111
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to South America

Cheapest flights from Charleston to South America

Fri 12/113:27 pm -
1 stop20h 33m
Mon 12/211:10 pm -
1 stop19h 28m
Deal found 10/31$563
Fri 12/113:27 pm -
1 stop20h 33m
Sun 12/201:10 pm -
1 stop19h 38m
Deal found 11/2$565
Tue 12/17:34 am -
1 stop28h 51m
Sat 12/54:40 pm -
1 stop19h 13m
Deal found 10/30$580
Thu 11/56:30 am -
1 stop16h 05m
Thu 11/128:15 am -
1 stop13h 44m
Deal found 10/31$623
Fri 11/278:30 am -
1 stop11h 00m
Tue 12/13:55 pm -
1 stop8h 09m
Deal found 11/1$635
Thu 11/267:05 am -
1 stop12h 25m
Sun 11/294:50 am -
2 stops19h 09m
Deal found 10/30$637
Wed 12/97:35 pm -
2 stops18h 01m
Sat 12/124:37 pm -
1 stop7h 54m
Deal found 11/1$639
Thu 11/58:25 pm -
2 stops21h 00m
Sun 11/83:45 pm -
2 stops16h 58m
Deal found 11/2$653
Tue 12/153:00 pm -
2 stops32h 25m
Tue 12/223:20 pm -
1 stop17h 18m
Deal found 10/31$680
Sat 12/58:12 pm -
1 stop16h 22m
Sat 1/303:15 pm -
1 stop8h 44m
Deal found 11/2$686
Mon 11/308:10 pm -
1 stop18h 05m
Fri 12/111:40 pm -
1 stop10h 57m
Deal found 11/2$702
Thu 12/37:40 am -
2 stops29h 15m
Mon 4/193:30 am -
2 stops15h 34m
Deal found 10/31$702

Find flight deals from Charleston to South America

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$513
(United Airlines)

One-way from

$243
(United Airlines)
Provider with most accurate pricing for Charleston-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Charleston-Sao Paulo (SAO) flights.
From Charleston to South America
One-way flight from Charleston to South America

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Sat 3/6

4:50 pm-10:10 pm

1 stop29h 20m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$243

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Tue 12/29

7:56 pm-10:10 pm

2 stops26h 14m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$251

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Tue 12/29

3:00 pm-12:00 pm

1 stop21h 00m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$262

CharlestonQuito

CHS Charleston - UIO Quito Mariscal Sucr

CHSUIO

Charleston

Wed 11/11

9:40 am-1:10 am

2 stops15h 30m

Quito Mariscal Sucr

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$265

CharlestonBogotá

CHS Charleston - BOG Bogotá El Dorado

CHSBOG

Charleston

Tue 12/29

3:00 pm-2:05 pm

1 stop23h 05m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$276

CharlestonCartagena

CHS Charleston - CTG Cartagena Rafael Nunez

CHSCTG

Charleston

Mon 12/7

7:35 pm-1:36 pm

2 stops18h 01m

Cartagena Rafael Nunez

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$343

CharlestonBogotá

CHS Charleston - BOG Bogotá El Dorado

CHSBOG

Charleston

Sun 12/27

2:13 pm-3:10 pm

2 stops24h 57m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$369

CharlestonBogotá

CHS Charleston - BOG Bogotá El Dorado

CHSBOG

Charleston

Fri 11/20

5:39 pm-6:45 pm

2 stops25h 06m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$382

CharlestonSantiago

CHS Charleston - SCL Santiago Arturo Merino Benitez

CHSSCL

Charleston

Sat 11/14

3:42 pm-11:36 pm

2 stops53h 54m

Santiago Arturo Merino Benitez

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$394

CharlestonBogotá

CHS Charleston - BOG Bogotá El Dorado

CHSBOG

Charleston

Mon 12/28

6:39 pm-10:35 pm

2 stops27h 56m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$402

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Showing 1-10 of 58 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, March is the cheapest month in which you can book a flight from Charleston to South America (average of $587). Flying from Charleston to South America in December is currently the most expensive (average of $1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

See what other customers who have flown with Delta,LATAM Airlines, andAmerican Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like United Airlines, American Airlines, and Delta fly from Charleston to South America in about 6h 45m. The time it takes to get you to your destination can typically vary by up to 8h 55m. Charleston and South America are separated by a distance of 1577 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Charleston to South America?

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, March is the cheapest month in which you can book a flight from Charleston to South America (average of $587). Flying from Charleston to South America in December is currently the most expensive (average of $1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Charleston to South America

Top 3 airlines flying from Charleston to South America

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$505Average$793FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$523Average$993FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$672Average$835FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.