$178+ Cheap flights from Charleston (CHS) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Charleston to South AmericaExplore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am -
1 stop15h 40m
Wed 11/1110:40 am -
1 stop11h 19m
Deal found 8/3![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:50 pm -
2 stops27h 20m
Sat 10/249:45 am -
2 stops13h 30m
Deal found 8/4![United Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am -
1 stop15h 40m
Fri 11/610:40 am -
1 stop29h 39m
Deal found 8/3![United Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:47 pm -
2 stops27h 23m
Fri 11/610:40 am -
1 stop29h 39m
Deal found 8/3![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:55 am -
2 stops36h 20m
Tue 11/1010:40 am -
1 stop11h 19m
Deal found 8/3![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:53 pm -
2 stops26h 17m
Sun 10/259:45 am -
1 stop11h 14m
Deal found 8/6![United Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:00 am -
2 stops38h 10m
Fri 10/99:45 am -
2 stops28h 15m
Deal found 8/4![United Airlines logo]()
$421
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:55 am -
2 stops36h 20m
Fri 11/610:40 am -
1 stop29h 39m
Deal found 8/3![United Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
1 stop16h 34m
Sun 11/81:30 am -
1 stop9h 31m
Deal found 8/3![American Airlines logo]()
$424
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
2 stops13h 30m
Sun 11/15:20 pm -
1 stop16h 39m
Deal found 8/6![Multiple Airlines logo]()
$454
This Avianca deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:08 am -
1 stop20h 27m
Fri 9/255:25 pm -
1 stop15h 52m
Deal found 8/4![Multiple Airlines logo]()
$481
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:50 am -
1 stop20h 05m
Fri 11/205:20 pm -
1 stop17h 05m
Deal found 8/6![Multiple Airlines logo]()
$487
Best flights from Charleston to South AmericaDiscover carefully curated flight deals from Charleston to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from Charleston to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:50 pm -
2 stops27h 20m
Sun 10/259:45 am -
2 stops27h 21m
Deal found 8/2![United Airlines logo]()
$400
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:50 am -
1 stop20h 05m
Thu 11/195:20 pm -
1 stop17h 05m
Deal found 8/6![Multiple Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 pm -
1 stop19h 05m
Sat 9/261:35 pm -
2 stops20h 04m
Deal found 8/5![American Airlines logo]()
$554
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:30 am -
1 stop8h 45m
Sun 10/185:35 am -
2 stops14h 23m
Deal found 8/3![Delta logo]()
$597
This LATAM Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:50 am -
2 stops14h 45m
Wed 10/78:55 am -
2 stops14h 04m
Deal found 8/5![LATAM Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:50 pm -
2 stops27h 20m
Sat 10/249:45 am -
2 stops13h 30m
Deal found 8/3![United Airlines logo]()
$400
This Azul deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Azul is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:27 pm -
1 stop23h 28m
Wed 9/1610:40 pm -
1 stop20h 50m
Deal found 8/4![Azul logo]()
$914
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am -
1 stop15h 10m
Sat 9/269:45 am -
1 stop11h 36m
Deal found 8/3![United Airlines logo]()
$432
This Avianca deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:08 am -
1 stop20h 27m
Fri 9/255:25 pm -
1 stop15h 52m
Deal found 8/4![Multiple Airlines logo]()
$481
This oojo deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 pm -
2 stops15h 10m
Sat 9/266:00 pm -
2 stops30h 43m
Deal found 8/5![GOL logo]()
$1,164
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:08 am -
1 stop20h 27m
Thu 9/245:25 pm -
1 stop15h 52m
Deal found 8/3![Multiple Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am -
1 stop8h 36m
Mon 11/94:37 pm -
2 stops21h 13m
Deal found 8/3![American Airlines logo]()
$598
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:59 pm -
2 stops20h 36m
Mon 11/92:35 pm -
1 stop9h 24m
Deal found 8/2![American Airlines logo]()
$603
This KAYAK deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am -
2 stops18h 30m
Tue 8/258:59 am -
2 stops26h 37m
Deal found 8/5![Copa Airlines logo]()
$1,354
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:43 pm -
1 stop11h 17m
Wed 12/211:40 pm -
1 stop18h 25m
Deal found 8/4![Delta logo]()
$711
This LATAM Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:50 am -
2 stops14h 45m
Mon 9/2112:15 am -
2 stops17h 58m
Deal found 8/5![LATAM Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop7h 35m
Sun 10/181:35 pm -
1 stop19h 57m
Deal found 8/3![American Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:20 am -
2 stops15h 10m
Wed 11/1811:40 pm -
1 stop13h 14m
Deal found 8/4![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:08 pm -
2 stops17h 27m
Tue 10/131:35 pm -
2 stops21h 58m
Deal found 8/3![American Airlines logo]()
$617
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:15 am -
1 stop19h 40m
Sun 11/295:20 pm -
1 stop17h 05m
Deal found 8/5![Multiple Airlines logo]()
$695
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 am -
2 stops15h 10m
Wed 12/211:40 pm -
1 stop13h 14m
Deal found 8/4![Delta logo]()
$711
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/252:57 pm -
2 stops23h 53m
Thu 12/314:00 pm -
2 stops18h 50m
Deal found 8/6![United Airlines logo]()
$749
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:40 am -
1 stop16h 15m
Sun 10/412:05 am -
1 stop14h 02m
Deal found 8/3![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop7h 35m
Mon 10/121:35 pm -
2 stops20h 28m
Deal found 8/1![American Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:58 pm -
2 stops29h 22m
Tue 9/2212:05 pm -
1 stop10h 54m
Deal found 8/2![Multiple Airlines logo]()
$724
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
2 stops18h 25m
Tue 10/612:35 am -
2 stops22h 40m
Deal found 8/3![United Airlines logo]()
$750
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:35 pm -
1 stop12h 25m
Mon 10/1912:05 am -
1 stop20h 07m
Deal found 8/3![Delta logo]()
$711
This Expedia deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:52 pm -
2 stops35h 08m
Thu 10/86:00 am -
2 stops16h 59m
Deal found 8/3![LATAM Airlines logo]()
$969
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:47 pm -
1 stop21h 08m
Mon 9/1410:40 pm -
2 stops39h 44m
Deal found 8/5![Multiple Airlines logo]()
$771
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:43 pm -
1 stop10h 12m
Wed 10/712:05 pm -
1 stop10h 54m
Deal found 8/4![Delta logo]()
$711
Last-minute flights from Charleston to South AmericaDiscover last-minute flight deals from Charleston to South America. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to South America. Data last updated August 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:00 am -
1 stop15h 10m
Sat 8/299:45 am -
2 stops23h 51m
Deal found 8/3![United Airlines logo]()
$557
This oojo deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:01 pm -
2 stops10h 34m
Sat 8/2910:55 am -
2 stops12h 04m
Deal found 8/2![LATAM Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:00 am -
1 stop7h 35m
Wed 9/301:35 pm -
1 stop7h 01m
Deal found 8/4![American Airlines logo]()
$563
This Avianca deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:08 am -
2 stops13h 32m
Thu 9/245:25 pm -
1 stop15h 52m
Deal found 8/3![Multiple Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:19 am -
2 stops35h 51m
Mon 9/289:45 am -
1 stop11h 36m
Deal found 8/3![United Airlines logo]()
$567
This Avianca deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:08 am -
2 stops13h 32m
Fri 9/255:25 pm -
1 stop15h 52m
Deal found 8/4![Multiple Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop19h 15m
Fri 9/251:35 pm -
1 stop26h 56m
Deal found 8/4![American Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:00 am -
1 stop15h 10m
Sat 9/269:45 am -
1 stop11h 36m
Deal found 8/3![United Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 pm -
1 stop19h 05m
Sat 9/261:35 pm -
2 stops20h 04m
Deal found 8/5![American Airlines logo]()
$554
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:50 pm -
2 stops27h 20m
Mon 10/59:45 am -
1 stop11h 36m
Deal found 8/6![United Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:41 pm -
2 stops18h 07m
Tue 10/66:00 am -
2 stops15h 09m
Deal found 8/6![American Airlines logo]()
$499
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:08 am -
2 stops22h 32m
Sun 10/411:25 am -
2 stops21h 54m
Deal found 8/6![Multiple Airlines logo]()
$516
One-way flights from Charleston to South AmericaSearch for one-way flight options from Charleston to South America. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from Charleston to South America. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:41 pm -
2 stops18h 07m
Deal found 8/1![American Airlines logo]()
$178
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:05 pm -
1 stop29h 05m
Deal found 8/1![United Airlines logo]()
$224
This FlightHub deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:56 pm -
2 stops18h 09m
Deal found 8/2![Multiple Airlines logo]()
$225
This Priceline deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:26 pm -
2 stops22h 14m
Deal found 8/2![Multiple Airlines logo]()
$235
This oojo deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:25 pm -
2 stops21h 15m
Deal found 8/5![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:13 pm -
3 stops41h 52m
Deal found 8/3![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:27 pm -
2 stops32h 33m
Deal found 8/3![Multiple Airlines logo]()
$270
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:50 am -
1 stop20h 05m
Deal found 8/5![Multiple Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am -
1 stop9h 15m
Deal found 8/4![American Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
3 stops17h 50m
Deal found 8/1![Multiple Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop19h 15m
Deal found 8/3![American Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:44 pm -
3 stops23h 13m
Deal found 8/4![Multiple Airlines logo]()
$312
Find flight deals from Charleston to South America
Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated August 7, 2026.
Round-trip from | $395 (United Airlines) |
|---|---|
One-way from | $178 (American Airlines) |
Popular in | April |
Cheapest in | September |
Average price | $621 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Charleston to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Sat 10/17
6:50 pm-9:10 pm
2 stops27h 20m
Medellín Jose Maria Cordova Intl
Sun 10/25
9:45 am-2:06 pm
2 stops27h 21m
$400
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Sat 10/17
6:50 pm-9:10 pm
2 stops27h 20m
Medellín Jose Maria Cordova Intl
Sat 10/24
9:45 am-12:15 am
2 stops13h 30m
$400
CharlestonMedellín
CHS Charleston - MDE Medellín Jose Maria Cordova Intl
CHSMDE
Charleston
Sat 9/19
7:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Sat 9/26
9:45 am-10:21 pm
1 stop11h 36m
$432
CharlestonQuito
CHS Charleston - UIO Quito Mariscal Sucr
CHSUIO
Charleston
Thu 11/12
10:50 am-6:55 am
1 stop20h 05m
Quito Mariscal Sucr
Thu 11/19
5:20 pm-10:25 am
1 stop17h 05m
$454
CharlestonQuito
CHS Charleston - UIO Quito Mariscal Sucr
CHSUIO
Charleston
Fri 9/18
11:08 am-6:35 am
1 stop20h 27m
Quito Mariscal Sucr
Fri 9/25
5:25 pm-10:17 am
1 stop15h 52m
$481
CharlestonQuito
CHS Charleston - UIO Quito Mariscal Sucr
CHSUIO
Charleston
Thu 9/17
11:08 am-6:35 am
1 stop20h 27m
Quito Mariscal Sucr
Thu 9/24
5:25 pm-10:17 am
1 stop15h 52m
$539
CharlestonCartagena
CHS Charleston - CTG Cartagena Rafael Nunez
CHSCTG
Charleston
Sat 9/19
6:30 pm-12:35 pm
1 stop19h 05m
Cartagena Rafael Nunez
Sat 9/26
1:35 pm-10:39 am
2 stops20h 04m
$554
CharlestonCartagena
CHS Charleston - CTG Cartagena Rafael Nunez
CHSCTG
Charleston
Thu 10/15
5:30 am-1:15 pm
1 stop8h 45m
Cartagena Rafael Nunez
Sun 10/18
5:35 am-8:58 pm
2 stops14h 23m
$597
CharlestonCartagena
CHS Charleston - CTG Cartagena Rafael Nunez
CHSCTG
Charleston
Mon 11/2
7:00 am-3:36 pm
1 stop8h 36m
Cartagena Rafael Nunez
Mon 11/9
4:37 pm-1:50 pm
2 stops21h 13m
$598
CharlestonCartagena
CHS Charleston - CTG Cartagena Rafael Nunez
CHSCTG
Charleston
Thu 11/5
4:59 pm-1:35 pm
2 stops20h 36m
Cartagena Rafael Nunez
Mon 11/9
2:35 pm-11:59 pm
1 stop9h 24m
$603
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from Charleston to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
CHS-MDE
CHS-UIO
CHS-CTG
CHS-LIM
CHS-VCP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to South America
CHS-0SA
CHS-MDE
CHS-UIO
CHS-CTG
CHS-LIM
What is the cheapest month to book a flight from Charleston to South America?
Currently, March is the cheapest month in which you can book a flight from Charleston to South America (average of $536). Flying from Charleston to South America in May is currently the most expensive (average of $881). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 7, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andAmerican Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to South America by cabin class
Find flights from Charleston to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and South America flights
Browse other Charleston and South America flight options. Last updated on August 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Charleston to South America flights
Consider these flights traveling from Charleston to South America.
Top 3 airlines flying from Charleston to South America
Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$301 | Average$733 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$523 | Average$951 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$650 | Average$796 | FlexibilityNo cancel fee | On-time81% |