South America

$131+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
feb. 20 — feb. 271
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Cheap flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/166:35 pm
CHS
-
BOG
1 stop19h 35m
Spirit Airlines
mié. 2/253:06 pm
BOG
-
CHS
1 stop26h 34m
Spirit Airlines
Deal found 1/19$275
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/166:35 pm
CHS
-
BOG
1 stop19h 35m
Spirit Airlines
vie. 2/273:06 pm
BOG
-
CHS
1 stop26h 34m
Spirit Airlines
Deal found 1/19$283
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/156:35 pm
CHS
-
BOG
1 stop19h 35m
Spirit Airlines
mié. 2/253:06 pm
BOG
-
CHS
1 stop26h 34m
Spirit Airlines
Deal found 1/19$284
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/76:35 pm
CHS
-
GYE
1 stop28h 29m
Spirit Airlines
sáb. 3/1411:59 pm
GYE
-
CHS
1 stop21h 34m
Spirit Airlines
Deal found 1/21$288
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/48:13 pm
CHS
-
GYE
1 stop18h 17m
American Airlines
mié. 3/112:30 pm
GYE
-
CHS
1 stop8h 29m
American Airlines
Deal found 1/20$289
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/156:35 pm
CHS
-
BOG
1 stop19h 35m
Spirit Airlines
vie. 2/273:06 pm
BOG
-
CHS
1 stop26h 34m
Spirit Airlines
Deal found 1/19$292
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/166:35 pm
CHS
-
BOG
1 stop19h 35m
Spirit Airlines
mar. 2/243:06 pm
BOG
-
CHS
2 stops24h 59m
Spirit Airlines
Deal found 1/19$301
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/156:35 pm
CHS
-
BOG
1 stop19h 35m
Spirit Airlines
mar. 2/243:06 pm
BOG
-
CHS
2 stops24h 59m
Spirit Airlines
Deal found 1/19$310
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/56:35 pm
CHS
-
CTG
1 stop18h 35m
Spirit Airlines
jue. 3/121:24 pm
CTG
-
CHS
1 stop8h 09m
Spirit Airlines
Deal found 1/19$316
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/276:35 pm
CHS
-
CTG
1 stop18h 35m
Spirit Airlines
mar. 3/32:21 pm
CTG
-
CHS
2 stops25h 44m
Spirit Airlines
Deal found 1/20$324
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/166:35 pm
CHS
-
BOG
1 stop19h 35m
Multiple Airlines
lun. 2/231:45 pm
BOG
-
CHS
1 stop18h 53m
Multiple Airlines
Deal found 1/19$330
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/276:35 pm
CHS
-
CTG
1 stop18h 35m
Spirit Airlines
mar. 3/101:21 pm
CTG
-
CHS
2 stops25h 44m
Spirit Airlines
Deal found 1/20$333

Find flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated enero 21, 2026.

Round-trip from

$275
(Kiwi.com)

One-way from

$131
(Trip.com)

Popular in

May

Cheapest in

September

Average price

$599
From Charleston to South America
One-way flight from Charleston to South America
Highest demand for flights based on searches. 8% potential increase in price ($56 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

sáb. 3/7

6:35 pm-11:04 pm

1 stop28h 29m

Guayaquil Jose Joaquin de Olmedo

sáb. 3/14

11:59 pm-10:33 pm

1 stop21h 34m

$288

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

mié. 3/4

6:05 am-10:41 pm

2 stops16h 36m

Guayaquil Jose Joaquin de Olmedo

mié. 3/11

2:30 pm-11:59 pm

1 stop8h 29m

$294

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

jue. 3/5

6:35 pm-1:10 pm

1 stop18h 35m

Cartagena Rafael Nunez

jue. 3/12

1:24 pm-10:33 pm

1 stop8h 09m

$316

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

sáb. 2/28

6:35 pm-1:10 pm

1 stop18h 35m

Cartagena Rafael Nunez

mar. 3/10

1:21 pm-4:05 pm

2 stops25h 44m

$324

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

lun. 2/16

6:35 pm-2:10 pm

1 stop19h 35m

Bogotá El Dorado

lun. 2/23

1:45 pm-8:38 am

1 stop18h 53m

$330

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

vie. 2/27

6:35 pm-1:10 pm

1 stop18h 35m

Cartagena Rafael Nunez

mar. 3/10

1:21 pm-4:05 pm

2 stops25h 44m

$333

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

lun. 2/16

6:35 pm-12:47 pm

2 stops18h 12m

Bogotá El Dorado

jue. 2/26

3:06 pm-5:40 pm

1 stop26h 34m

$341

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

sáb. 2/28

6:35 pm-1:10 pm

1 stop18h 35m

Cartagena Rafael Nunez

mar. 3/10

1:21 pm-8:38 am

2 stops42h 17m

$346

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

mié. 2/18

5:00 pm-12:47 pm

2 stops19h 47m

Bogotá El Dorado

lun. 2/23

1:45 pm-8:38 am

1 stop18h 53m

$351

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

vie. 3/6

12:36 pm-5:14 am

1 stop16h 38m

Guayaquil Jose Joaquin de Olmedo

vie. 3/13

6:25 am-8:03 pm

1 stop12h 38m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 52 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, November is the cheapest month in which you can book a flight from Charleston to South America (average of $113). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated enero 21, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to South America?

    Airlines like Spirit Airlines, American Airlines, and JetBlue fly from Charleston to South America in about 16h 36m. The time it takes to get you to your destination can typically vary by up to 11h 53m. Charleston and South America are separated by a distance of 2420 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Charleston to South America one-way?

    The cheapest airlines for a one-way flight from Charleston to South America are American Airlines ($296), Delta ($356), and LATAM Airlines ($356).

  • What are the most popular routes from Charleston to South America?

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, November is the cheapest month in which you can book a flight from Charleston to South America (average of $113). Flying from Charleston to South America in May is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charleston to South America

Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$301Average$877FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$435Average$783FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$542Average$737FlexibilityNo cancel feeOn-time81%

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