$183+ Cheap flights from Buffalo (BUF) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
Aug 30 — Sep 61
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to South America
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Cheapest flights from Buffalo to South AmericaExplore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2026.
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
BUF
- CTG
1 stop6h 52m
JetBlue
Fri 9/182:00 pm
CTG
- BUF
1 stop7h 56m
JetBlue
Deal found 7/29![JetBlue logo]()
$391
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:56 pm
BUF
- CTG
2 stops18h 39m
American Airlines
Fri 9/181:35 pm
CTG
- BUF
2 stops20h 45m
American Airlines
Deal found 7/27![American Airlines logo]()
$412
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Thu 10/151:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$426
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am
BUF
- CTG
1 stop8h 15m
Delta
Sat 10/242:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 7/30![Delta logo]()
$447
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Thu 10/151:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$452
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:24 pm
BUF
- CTG
2 stops21h 11m
American Airlines
Sat 10/171:35 pm
CTG
- BUF
2 stops19h 43m
American Airlines
Deal found 7/25![American Airlines logo]()
$462
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 am
BUF
- MDE
2 stops18h 40m
LATAM Airlines
Fri 10/168:55 am
MDE
- BUF
2 stops25h 21m
LATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$470
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Fri 10/161:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$478
This Justfly.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am
BUF
- CTG
1 stop6h 52m
JetBlue
Thu 10/1512:35 pm
CTG
- BUF
1 stop10h 23m
JetBlue
Deal found 7/27![JetBlue logo]()
$494
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am
BUF
- CTG
1 stop8h 19m
JetBlue
Tue 11/31:40 pm
CTG
- BUF
1 stop10h 22m
JetBlue
Deal found 7/28![JetBlue logo]()
$496
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:38 am
BUF
- MDE
2 stops14h 37m
American Airlines
Sat 9/191:53 pm
MDE
- BUF
2 stops20h 46m
American Airlines
Deal found 7/26![American Airlines logo]()
$498
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Thu 10/151:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$506
Best flights from Buffalo to South AmericaDiscover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2026.
Discover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
BUF
- CTG
1 stop6h 52m
JetBlue
Fri 9/182:00 pm
CTG
- BUF
1 stop7h 56m
JetBlue
Deal found 7/27![JetBlue logo]()
$392
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am
BUF
- CTG
1 stop8h 15m
Delta
Sat 10/242:30 pm
CTG
- BUF
1 stop8h 29m
Delta
Deal found 7/30![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:38 am
BUF
- MDE
2 stops14h 37m
American Airlines
Sat 9/191:53 pm
MDE
- BUF
2 stops20h 46m
American Airlines
Deal found 7/26![American Airlines logo]()
$498
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:06 pm
BUF
- BOG
1 stop9h 24m
Multiple Airlines
Thu 9/175:40 pm
BOG
- BUF
2 stops13h 30m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$537
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:30 am
BUF
- BOG
2 stops12h 30m
United Airlines
Fri 9/187:20 am
BOG
- BUF
2 stops24h 48m
United Airlines
Deal found 7/28![United Airlines logo]()
$611
This LATAM Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:19 pm
BUF
- BOG
1 stop19h 21m
LATAM Airlines
Tue 8/258:40 am
BOG
- BUF
2 stops14h 19m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$632
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:59 pm
BUF
- MDE
2 stops18h 11m
Avianca
Sat 9/194:50 am
MDE
- BUF
2 stops13h 14m
Avianca
Deal found 7/30![Avianca logo]()
$672
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Thu 10/151:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$426
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am
BUF
- CTG
1 stop8h 19m
JetBlue
Tue 11/31:40 pm
CTG
- BUF
1 stop10h 22m
JetBlue
Deal found 7/28![JetBlue logo]()
$496
This Avianca deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:50 pm
BUF
- BOG
1 stop11h 25m
Multiple Airlines
Mon 9/2111:55 pm
BOG
- BUF
1 stop12h 34m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$577
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:50 pm
BUF
- CTG
2 stops18h 40m
American Airlines
Wed 1/64:30 pm
CTG
- BUF
2 stops18h 55m
American Airlines
Deal found 7/26![American Airlines logo]()
$603
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Thu 10/151:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$506
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:30 am
BUF
- BOG
2 stops12h 30m
United Airlines
Fri 9/48:30 am
BOG
- BUF
2 stops23h 58m
United Airlines
Deal found 7/26![United Airlines logo]()
$622
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am
BUF
- BOG
1 stop8h 40m
Delta
Wed 10/219:00 am
BOG
- BUF
1 stop13h 59m
Delta
Deal found 7/30![Delta logo]()
$625
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:55 pm
BUF
- CTG
1 stop19h 10m
LATAM Airlines
Wed 1/63:25 pm
CTG
- BUF
1 stop26h 06m
LATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$634
This Avianca deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:50 pm
BUF
- BOG
1 stop11h 25m
Multiple Airlines
Fri 9/189:05 am
BOG
- BUF
1 stop12h 51m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:30 am
BUF
- BOG
2 stops16h 47m
American Airlines
Mon 9/216:30 am
BOG
- BUF
2 stops16h 10m
American Airlines
Deal found 7/31![American Airlines logo]()
$622
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am
BUF
- BOG
1 stop14h 15m
Delta
Tue 10/208:40 am
BOG
- BUF
2 stops14h 19m
Delta
Deal found 7/30![Delta logo]()
$630
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am
BUF
- CTG
2 stops18h 00m
United Airlines
Tue 11/36:25 am
CTG
- BUF
2 stops16h 34m
United Airlines
Deal found 7/30![United Airlines logo]()
$640
This Avianca deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:02 pm
BUF
- BOG
1 stop11h 13m
Multiple Airlines
Tue 8/259:05 am
BOG
- BUF
1 stop9h 20m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$604
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Wed 10/141:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$552
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:50 pm
BUF
- CTG
2 stops15h 00m
Multiple Airlines
Fri 9/182:00 pm
CTG
- BUF
1 stop7h 56m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$606
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Fri 10/161:30 pm
MDE
- BUF
1 stop9h 28m
JetBlue
Deal found 7/28![JetBlue logo]()
$578
This oojo deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:20 pm
BUF
- LIM
1 stop12h 40m
LATAM Airlines
Wed 11/1111:30 pm
LIM
- BUF
2 stops35h 00m
LATAM Airlines
Deal found 7/26![LATAM Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:49 pm
BUF
- MDE
2 stops20h 59m
American Airlines
Mon 9/141:53 pm
MDE
- BUF
2 stops20h 25m
American Airlines
Deal found 7/31![American Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:05 am
BUF
- UIO
1 stop13h 54m
Delta
Tue 9/2912:59 am
UIO
- BUF
1 stop12h 52m
Delta
Deal found 7/27![Delta logo]()
$719
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:59 pm
BUF
- UIO
2 stops28h 26m
United Airlines
Mon 9/2112:35 am
UIO
- BUF
2 stops12h 43m
United Airlines
Deal found 7/27![United Airlines logo]()
$734
This Justfly.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am
BUF
- MDE
1 stop15h 25m
Multiple Airlines
Tue 10/1310:40 pm
MDE
- BUF
1 stop15h 21m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$633
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
BUF
- MDE
1 stop8h 19m
JetBlue
Sat 9/191:30 pm
MDE
- BUF
1 stop8h 26m
JetBlue
Deal found 7/26![JetBlue logo]()
$582
This oojo deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am
BUF
- LIM
1 stop16h 55m
LATAM Airlines
Thu 10/2212:05 am
LIM
- BUF
1 stop14h 06m
LATAM Airlines
Deal found 7/30![LATAM Airlines logo]()
$815
Last-minute flights from Buffalo to South AmericaDiscover last-minute flight deals from Buffalo to South America. Data last updated July 31, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to South America. Data last updated July 31, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:58 pm
BUF
- MDE
2 stops28h 12m
United Airlines
Wed 8/199:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/25![United Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:34 pm
BUF
- CTG
2 stops19h 41m
American Airlines
Sat 8/221:35 pm
CTG
- BUF
2 stops19h 04m
American Airlines
Deal found 7/27![American Airlines logo]()
$589
This Travelocity deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:05 am
BUF
- CTG
1 stop8h 10m
LATAM Airlines
Sat 8/222:30 pm
CTG
- BUF
1 stop19h 38m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$625
This Expedia deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:05 am
BUF
- CTG
1 stop8h 10m
Multiple Airlines
Sat 8/222:15 pm
CTG
- BUF
2 stops16h 37m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$666
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:02 pm
BUF
- BOG
1 stop11h 13m
Multiple Airlines
Tue 8/259:05 am
BOG
- BUF
1 stop9h 20m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:27 am
BUF
- BOG
2 stops14h 43m
Delta
Tue 8/252:55 pm
BOG
- BUF
2 stops19h 27m
Delta
Deal found 7/29![Delta logo]()
$632
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
BUF
- BOG
2 stops16h 17m
American Airlines
Tue 8/256:30 am
BOG
- BUF
2 stops16h 06m
American Airlines
Deal found 7/26![American Airlines logo]()
$633
This LATAM Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:19 pm
BUF
- BOG
1 stop19h 21m
LATAM Airlines
Tue 8/2510:35 am
BOG
- BUF
2 stops12h 24m
LATAM Airlines
Deal found 7/26![LATAM Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:48 pm
BUF
- CTG
2 stops18h 17m
Delta
Tue 8/252:30 pm
CTG
- BUF
2 stops46h 17m
Delta
Deal found 7/28![Delta logo]()
$554
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:05 pm
BUF
- CTG
1 stop17h 30m
JetBlue
Tue 8/2512:35 pm
CTG
- BUF
1 stop29h 50m
JetBlue
Deal found 7/28![JetBlue logo]()
$643
This Justfly.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:15 am
BUF
- BOG
1 stop12h 15m
Multiple Airlines
Mon 9/74:05 pm
BOG
- BUF
1 stop16h 02m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:30 am
BUF
- BOG
2 stops12h 30m
United Airlines
Fri 9/48:30 am
BOG
- BUF
2 stops23h 58m
United Airlines
Deal found 7/26![United Airlines logo]()
$622
One-way flights from Buffalo to South AmericaSearch for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated July 31, 2026.
Search for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated July 31, 2026.
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:55 am
BUF
- MDE
2 stops39h 15m
United Airlines
Deal found 7/26![United Airlines logo]()
$183
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:21 pm
BUF
- CTG
2 stops20h 14m
American Airlines
Deal found 7/30![American Airlines logo]()
$193
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am
BUF
- CTG
1 stop8h 05m
Delta
Deal found 7/30![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:46 pm
BUF
- CTG
2 stops20h 50m
American Airlines
Deal found 7/30![American Airlines logo]()
$198
This BusinessClass deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:32 pm
BUF
- CTG
1 stop25h 33m
LATAM Airlines
Deal found 7/30![LATAM Airlines logo]()
$254
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am
BUF
- MDE
2 stops16h 25m
LATAM Airlines
Deal found 7/30![LATAM Airlines logo]()
$260
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:50 pm
BUF
- BOG
1 stop11h 25m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:13 pm
BUF
- CTG
3 stops33h 47m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:49 pm
BUF
- BOG
2 stops11h 06m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:40 pm
BUF
- BOG
3 stops22h 26m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:40 pm
BUF
- BOG
3 stops26h 20m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:40 pm
BUF
- MDE
3 stops26h 05m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$279
Find flight deals from Buffalo to South America
Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated July 31, 2026.
Round-trip from | $391 (Cheapflightsfares) |
|---|---|
One-way from | $183 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Mon 9/14
7:00 am-12:52 pm
1 stop6h 52m
Cartagena Rafael Nunez
Fri 9/18
2:00 pm-10:56 pm
1 stop7h 56m
$392
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Sun 10/4
7:00 am-2:19 pm
1 stop8h 19m
Medellín Jose Maria Cordova Intl
Thu 10/15
1:30 pm-11:58 pm
1 stop9h 28m
$426
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Sat 10/17
6:00 am-1:15 pm
1 stop8h 15m
Cartagena Rafael Nunez
Sat 10/24
2:30 pm-11:59 pm
1 stop8h 29m
$447
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Sat 10/31
6:00 am-1:19 pm
1 stop8h 19m
Cartagena Rafael Nunez
Tue 11/3
1:40 pm-12:02 am
1 stop10h 22m
$496
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Mon 9/14
6:38 am-8:15 pm
2 stops14h 37m
Medellín Jose Maria Cordova Intl
Sat 9/19
1:53 pm-11:39 am
2 stops20h 46m
$498
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Fri 10/2
7:00 am-2:19 pm
1 stop8h 19m
Medellín Jose Maria Cordova Intl
Thu 10/15
1:30 pm-11:58 pm
1 stop9h 28m
$506
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Thu 9/10
12:06 pm-8:30 pm
1 stop9h 24m
Bogotá El Dorado
Thu 9/17
5:40 pm-8:10 am
2 stops13h 30m
$537
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Sun 10/4
7:00 am-2:19 pm
1 stop8h 19m
Medellín Jose Maria Cordova Intl
Wed 10/14
1:30 pm-11:58 pm
1 stop9h 28m
$552
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Mon 9/14
7:50 pm-6:15 am
1 stop11h 25m
Bogotá El Dorado
Mon 9/21
11:55 pm-1:29 pm
1 stop12h 34m
$577
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Tue 10/6
7:00 am-2:19 pm
1 stop8h 19m
Medellín Jose Maria Cordova Intl
Fri 10/16
1:30 pm-11:58 pm
1 stop9h 28m
$578
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Buffalo to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
BUF-CTG
BUF-BOG
BUF-MDE
BUF-UIO
BUF-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to South America
BUF-0SA
BUF-CTG
BUF-BOG
BUF-MDE
BUF-UIO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 31, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to South America by cabin class
Find flights from Buffalo to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and South America flights
Browse other Buffalo and South America flight options. Last updated on July 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Buffalo to South America flights
Consider these flights traveling from Buffalo to South America.
Top 4 airlines flying from Buffalo to South America
Discover the top 4 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$320 | Average$735 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$442 | Average$479 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$809 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,163 | Average$1,271 | FlexibilityNo cancel fee | On-time69% |