$128+ Cheap flights from Buffalo (BUF) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
May 27 — Jun 31
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to South America
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Cheapest flights from Buffalo to South AmericaExplore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
This Expedia deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
BUF
- MDE
1 stop9h 10m
JetBlue
Wed 6/31:25 pm
MDE
- BUF
2 stops18h 33m
JetBlue
Deal found 4/27![JetBlue logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:45 pm
BUF
- MDE
2 stops26h 25m
United Airlines
Sat 5/29:45 am
MDE
- BUF
2 stops31h 50m
United Airlines
Deal found 4/25![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:40 pm
BUF
- CTG
2 stops19h 33m
American Airlines
Tue 6/161:35 pm
CTG
- BUF
2 stops21h 44m
American Airlines
Deal found 4/25![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:40 pm
BUF
- CTG
2 stops21h 55m
American Airlines
Fri 8/211:35 pm
CTG
- BUF
2 stops20h 33m
American Airlines
Deal found 4/24![American Airlines logo]()
$470
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:55 pm
BUF
- MDE
2 stops28h 15m
United Airlines
Wed 5/139:45 am
MDE
- BUF
2 stops23h 05m
United Airlines
Deal found 4/26![United Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:38 pm
BUF
- CTG
2 stops21h 37m
American Airlines
Mon 8/311:35 pm
CTG
- BUF
2 stops22h 03m
American Airlines
Deal found 4/23![American Airlines logo]()
$511
This LATAM Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
BUF
- CTG
1 stop8h 20m
LATAM Airlines
Sat 5/302:30 pm
CTG
- BUF
1 stop8h 29m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$547
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:57 pm
BUF
- MDE
2 stops28h 13m
United Airlines
Wed 6/39:45 am
MDE
- BUF
2 stops23h 06m
United Airlines
Deal found 4/27![United Airlines logo]()
$556
This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
BUF
- BOG
1 stop14h 15m
Multiple Airlines
Wed 9/168:40 am
BOG
- BUF
1 stop10h 37m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$565
This Avianca deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:10 pm
BUF
- MDE
2 stops12h 25m
Multiple Airlines
Mon 10/2611:00 pm
MDE
- BUF
1 stop14h 28m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$566
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:07 am
BUF
- BOG
2 stops12h 43m
Delta
Thu 7/239:00 am
BOG
- BUF
1 stop13h 59m
Delta
Deal found 4/24![Delta logo]()
$570
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
Mon 10/269:45 am
MDE
- BUF
2 stops23h 41m
United Airlines
Deal found 4/27![United Airlines logo]()
$570
Best flights from Buffalo to South AmericaDiscover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
Discover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:40 pm
BUF
- CTG
2 stops19h 33m
American Airlines
Tue 6/161:35 pm
CTG
- BUF
2 stops21h 44m
American Airlines
Deal found 4/25![American Airlines logo]()
$460
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:55 pm
BUF
- MDE
2 stops28h 15m
United Airlines
Wed 5/139:45 am
MDE
- BUF
2 stops23h 05m
United Airlines
Deal found 4/26![United Airlines logo]()
$496
This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
BUF
- BOG
1 stop14h 15m
Multiple Airlines
Wed 9/168:40 am
BOG
- BUF
1 stop10h 37m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:07 am
BUF
- BOG
2 stops12h 43m
Delta
Thu 7/239:00 am
BOG
- BUF
1 stop13h 59m
Delta
Deal found 4/24![Delta logo]()
$570
This Cheapflightsfares deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:03 am
BUF
- CTG
1 stop8h 37m
JetBlue
Tue 6/162:55 pm
CTG
- BUF
1 stop16h 05m
JetBlue
Deal found 4/25![JetBlue logo]()
$582
This LATAM Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:15 am
BUF
- CTG
2 stops13h 15m
LATAM Airlines
Thu 5/144:25 am
CTG
- BUF
2 stops18h 34m
LATAM Airlines
Deal found 4/26![LATAM Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:40 pm
BUF
- CTG
2 stops21h 55m
American Airlines
Fri 8/211:35 pm
CTG
- BUF
2 stops20h 33m
American Airlines
Deal found 4/24![American Airlines logo]()
$470
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:57 pm
BUF
- MDE
2 stops28h 13m
United Airlines
Wed 6/39:45 am
MDE
- BUF
2 stops23h 06m
United Airlines
Deal found 4/27![United Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:38 pm
BUF
- CTG
2 stops21h 37m
American Airlines
Mon 8/311:35 pm
CTG
- BUF
2 stops22h 03m
American Airlines
Deal found 4/23![American Airlines logo]()
$511
This Avianca deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:10 pm
BUF
- MDE
2 stops12h 25m
Multiple Airlines
Mon 10/2611:00 pm
MDE
- BUF
1 stop14h 28m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$566
This Expedia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:55 pm
BUF
- CTG
1 stop16h 40m
JetBlue
Fri 8/2112:35 pm
CTG
- BUF
2 stops20h 06m
JetBlue
Deal found 4/24![JetBlue logo]()
$602
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
BUF
- BOG
2 stops14h 20m
United Airlines
Tue 9/1512:14 am
BOG
- BUF
2 stops22h 38m
United Airlines
Deal found 4/25![United Airlines logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:49 pm
BUF
- BOG
1 stop22h 56m
Multiple Airlines
Sat 5/168:40 am
BOG
- BUF
2 stops25h 01m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$596
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am
BUF
- UIO
2 stops14h 05m
Delta
Mon 10/1212:59 am
UIO
- BUF
1 stop13h 28m
Delta
Deal found 4/23![Delta logo]()
$726
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:00 am
BUF
- BOG
1 stop16h 38m
American Airlines
Sun 6/146:30 am
BOG
- BUF
2 stops16h 24m
American Airlines
Deal found 4/22![American Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:52 pm
BUF
- BOG
2 stops27h 08m
United Airlines
Tue 6/211:10 pm
BOG
- BUF
2 stops23h 49m
United Airlines
Deal found 4/27![United Airlines logo]()
$602
This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
BUF
- UIO
1 stop13h 59m
LATAM Airlines
Tue 6/166:50 pm
UIO
- BUF
2 stops15h 19m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$734
This Kissandfly.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:01 am
BUF
- EZE
1 stop23h 04m
British Airways
Wed 6/178:35 pm
EZE
- BUF
2 stops18h 46m
British Airways
Deal found 4/26![British Airways logo]()
$1,645
This FlightHub deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:40 pm
BUF
- LIM
1 stop10h 20m
LATAM Airlines
Mon 10/2612:15 am
LIM
- BUF
2 stops14h 12m
LATAM Airlines
Deal found 4/26![LATAM Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:29 am
BUF
- UIO
2 stops13h 36m
Delta
Mon 7/2712:59 am
UIO
- BUF
1 stop9h 12m
Delta
Deal found 4/25![Delta logo]()
$765
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:52 pm
BUF
- BOG
2 stops27h 08m
United Airlines
Thu 6/1811:10 pm
BOG
- BUF
2 stops23h 49m
United Airlines
Deal found 4/27![United Airlines logo]()
$635
This oojo deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:05 am
BUF
- MDE
1 stop30h 15m
Multiple Airlines
Sun 6/146:35 am
MDE
- BUF
1 stop12h 53m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$702
This oojo deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
BUF
- SDU
2 stops29h 50m
Azul
Wed 5/276:10 am
SDU
- BUF
2 stops38h 13m
Azul
Deal found 4/27![Azul logo]()
$1,887
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am
BUF
- LIM
2 stops16h 35m
Delta
Mon 10/2612:05 am
LIM
- BUF
2 stops17h 32m
Delta
Deal found 4/26![Delta logo]()
$783
This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:36 am
BUF
- UIO
2 stops27h 09m
Multiple Airlines
Tue 6/166:50 pm
UIO
- BUF
2 stops23h 00m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$714
This KAYAK deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:09 pm
BUF
- LIM
2 stops17h 51m
LATAM Airlines
Mon 10/512:15 am
LIM
- BUF
2 stops17h 22m
LATAM Airlines
Deal found 4/26![LATAM Airlines logo]()
$788
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:52 pm
BUF
- MDE
2 stops28h 18m
United Airlines
Sat 6/209:45 am
MDE
- BUF
2 stops23h 20m
United Airlines
Deal found 4/26![United Airlines logo]()
$670
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:32 am
BUF
- MDE
2 stops15h 44m
American Airlines
Fri 7/2412:30 am
MDE
- BUF
2 stops12h 49m
American Airlines
Deal found 4/24![American Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:04 pm
BUF
- LIM
2 stops17h 56m
Delta
Tue 7/288:15 am
LIM
- BUF
2 stops14h 43m
Delta
Deal found 4/24![Delta logo]()
$810
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
Wed 9/309:45 am
MDE
- BUF
2 stops23h 04m
United Airlines
Deal found 4/22![United Airlines logo]()
$675
Last-minute flights from Buffalo to South AmericaDiscover last-minute flight deals from Buffalo to South America. Data last updated April 27, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to South America. Data last updated April 27, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:00 am
BUF
- BOG
1 stop21h 45m
Multiple Airlines
Wed 4/291:40 pm
BOG
- BUF
2 stops18h 50m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$625
This LATAM Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
BUF
- CTG
1 stop8h 20m
LATAM Airlines
Sat 5/302:30 pm
CTG
- BUF
1 stop8h 29m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$547
This Expedia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:01 pm
BUF
- CTG
2 stops18h 54m
Multiple Airlines
Sat 5/305:25 pm
CTG
- BUF
2 stops14h 33m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$665
This Avianca deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:50 pm
BUF
- BOG
1 stop12h 40m
Avianca
Thu 5/72:50 pm
BOG
- BUF
1 stop17h 51m
Avianca
Deal found 4/22![Avianca logo]()
$753
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:49 pm
BUF
- BOG
1 stop22h 56m
Multiple Airlines
Sat 5/168:40 am
BOG
- BUF
2 stops25h 01m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$596
This KAYAK deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:55 pm
BUF
- BOG
2 stops26h 25m
Avianca
Sat 5/168:30 am
BOG
- BUF
2 stops24h 12m
Avianca
Deal found 4/23![Avianca logo]()
$741
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:55 pm
BUF
- MDE
2 stops28h 15m
United Airlines
Wed 5/139:45 am
MDE
- BUF
2 stops23h 05m
United Airlines
Deal found 4/26![United Airlines logo]()
$496
This LATAM Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:15 am
BUF
- CTG
2 stops13h 15m
LATAM Airlines
Thu 5/144:25 am
CTG
- BUF
2 stops18h 34m
LATAM Airlines
Deal found 4/26![LATAM Airlines logo]()
$624
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:52 pm
BUF
- BOG
2 stops27h 08m
United Airlines
Tue 6/211:10 pm
BOG
- BUF
2 stops23h 49m
United Airlines
Deal found 4/27![United Airlines logo]()
$602
This Justfly.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:16 pm
BUF
- BOG
1 stop24h 44m
Multiple Airlines
Tue 6/211:15 pm
BOG
- BUF
1 stop13h 27m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$624
This Expedia deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
BUF
- MDE
1 stop9h 10m
JetBlue
Wed 6/31:25 pm
MDE
- BUF
2 stops18h 33m
JetBlue
Deal found 4/27![JetBlue logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:57 pm
BUF
- MDE
2 stops28h 13m
United Airlines
Wed 6/39:45 am
MDE
- BUF
2 stops23h 06m
United Airlines
Deal found 4/27![United Airlines logo]()
$556
One-way flights from Buffalo to South AmericaSearch for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
Search for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
BUF
- MDE
2 stops15h 10m
United Airlines
Deal found 4/25![United Airlines logo]()
$128
This KAYAK deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:52 pm
BUF
- MDE
2 stops28h 18m
Avianca
Deal found 4/24![Avianca logo]()
$133
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
BUF
- MDE
2 stops16h 10m
United Airlines
Deal found 4/24![United Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:35 am
BUF
- MDE
3 stops32h 15m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:41 pm
BUF
- UIO
2 stops28h 52m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:50 pm
BUF
- MDE
2 stops23h 35m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$236
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:00 am
BUF
- MDE
2 stops15h 10m
United Airlines
Deal found 4/25![United Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:49 pm
BUF
- UIO
3 stops24h 21m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:35 am
BUF
- MDE
3 stops33h 05m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$260
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:00 am
BUF
- MDE
2 stops39h 10m
United Airlines
Deal found 4/24![United Airlines logo]()
$261
This Aviatur deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am
BUF
- BOG
1 stop15h 30m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am
BUF
- BOG
2 stops15h 15m
American Airlines
Deal found 4/27![American Airlines logo]()
$274
Find flight deals from Buffalo to South America
Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated April 27, 2026.
Round-trip from | $439 (Expedia) |
|---|---|
One-way from | $128 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Tue 6/9
7:40 pm-2:13 pm
2 stops19h 33m
Cartagena Rafael Nunez
Tue 6/16
1:35 pm-12:19 pm
2 stops21h 44m
$460
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Sun 8/16
3:40 pm-12:35 pm
2 stops21h 55m
Cartagena Rafael Nunez
Fri 8/21
1:35 pm-11:08 am
2 stops20h 33m
$470
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Sat 5/9
5:55 pm-9:10 pm
2 stops28h 15m
Medellín Jose Maria Cordova Intl
Wed 5/13
9:45 am-9:50 am
2 stops23h 05m
$496
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Thu 8/27
5:38 pm-2:15 pm
2 stops21h 37m
Cartagena Rafael Nunez
Mon 8/31
1:35 pm-12:38 pm
2 stops22h 03m
$511
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Wed 5/27
5:57 pm-9:10 pm
2 stops28h 13m
Medellín Jose Maria Cordova Intl
Wed 6/3
9:45 am-9:51 am
2 stops23h 06m
$556
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Tue 9/1
6:00 am-7:15 pm
1 stop14h 15m
Bogotá El Dorado
Wed 9/16
8:40 am-8:17 pm
1 stop10h 37m
$565
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Thu 10/22
12:10 pm-11:35 pm
2 stops12h 25m
Medellín Jose Maria Cordova Intl
Mon 10/26
11:00 pm-2:28 pm
1 stop14h 28m
$566
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Tue 7/14
6:07 am-5:50 pm
2 stops12h 43m
Bogotá El Dorado
Thu 7/23
9:00 am-11:59 pm
1 stop13h 59m
$570
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Tue 9/1
6:00 am-7:20 pm
2 stops14h 20m
Bogotá El Dorado
Tue 9/15
12:14 am-11:52 pm
2 stops22h 38m
$570
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Tue 6/9
6:03 am-1:40 pm
1 stop8h 37m
Cartagena Rafael Nunez
Tue 6/16
2:55 pm-8:00 am
1 stop16h 05m
$582
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Buffalo to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
BUF-MDE
BUF-UIO
BUF-BOG
BUF-CTG
BUF-EZE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to South America
BUF-0SA
BUF-MDE
BUF-UIO
BUF-BOG
BUF-CTG
What is the cheapest month to book a flight from Buffalo to South America?
Currently, January is the cheapest month in which you can book a flight from Buffalo to South America (average of $320). Flying from Buffalo to South America in April is currently the most expensive (average of $711). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 27, 2026.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Food
7.2
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Food
7.2
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKymberlee,Oct 2024
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to South America by cabin class
Find flights from Buffalo to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and South America flights
Browse other Buffalo and South America flight options. Last updated on April 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Buffalo to South America flights
Consider these flights traveling from Buffalo to South America.
Top 2 airlines flying from Buffalo to South America
Discover the top 2 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$320 | Average$694 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$587 | Average$795 | FlexibilityNo cancel fee | On-time81% |