$170+ Cheap flights from Buffalo (BUF) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to South America
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Cheapest flights from Buffalo to South AmericaExplore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:21 pm -
2 stops19h 51m
Fri 11/203:11 pm -
2 stops18h 59m
Deal found 9/10![American Airlines logo]()
$384
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
1 stop8h 21m
Thu 10/2912:44 pm -
1 stop10h 14m
Deal found 9/9![JetBlue logo]()
$488
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:34 am -
2 stops12h 00m
Sat 11/143:12 pm -
2 stops19h 28m
Deal found 9/9![American Airlines logo]()
$509
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:53 pm -
2 stops17h 42m
Sun 10/251:35 pm -
2 stops20h 03m
Deal found 9/10![American Airlines logo]()
$512
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:30 am -
2 stops15h 40m
Fri 11/1310:40 am -
2 stops34h 11m
Deal found 9/12![United Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:17 pm -
2 stops20h 18m
Wed 10/141:35 pm -
2 stops22h 11m
Deal found 9/9![American Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:59 pm -
2 stops26h 11m
Fri 10/239:45 am -
2 stops22h 23m
Deal found 9/11![United Airlines logo]()
$576
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:44 am -
1 stop16h 43m
Sat 12/51:15 pm -
1 stop10h 14m
Deal found 9/8![American Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:30 am -
2 stops15h 45m
Sun 11/110:45 am -
2 stops22h 36m
Deal found 9/10![United Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:56 am -
2 stops17h 42m
Fri 12/187:30 am -
1 stop15h 54m
Deal found 9/10![American Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am -
2 stops15h 10m
Fri 9/259:45 am -
2 stops22h 44m
Deal found 9/11![United Airlines logo]()
$608
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:53 pm -
1 stop11h 22m
Tue 10/271:40 pm -
1 stop9h 18m
Deal found 9/9![Multiple Airlines logo]()
$611
Best flights from Buffalo to South AmericaDiscover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/276:45 pm -
2 stops27h 30m
Wed 3/310:45 am -
2 stops35h 52m
Deal found 9/7![United Airlines logo]()
$418
This JetBlue deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
1 stop8h 21m
Thu 10/2912:44 pm -
1 stop10h 14m
Deal found 9/7![JetBlue logo]()
$488
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:44 pm -
2 stops18h 31m
Sat 12/51:15 pm -
1 stop10h 14m
Deal found 9/8![American Airlines logo]()
$600
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:59 pm -
1 stop13h 06m
Sat 11/148:10 pm -
1 stop11h 57m
Deal found 9/12![Multiple Airlines logo]()
$619
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:35 pm -
1 stop7h 40m
Fri 10/239:00 am -
1 stop13h 59m
Deal found 9/7![LATAM Airlines logo]()
$648
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:15 am -
2 stops12h 35m
Sat 10/249:00 am -
1 stop13h 59m
Deal found 9/8![Delta logo]()
$653
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:52 pm -
2 stops24h 23m
Wed 10/287:10 am -
2 stops25h 11m
Deal found 9/10![Avianca logo]()
$788
This BusinessClass deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:48 pm -
1 stop15h 12m
Thu 10/2910:35 pm -
1 stop25h 19m
Deal found 9/7![GOL logo]()
$1,226
This JetBlue deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:35 am -
1 stop7h 12m
Wed 10/282:52 pm -
1 stop8h 06m
Deal found 9/7![JetBlue logo]()
$614
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:59 pm -
1 stop13h 06m
Fri 11/2011:00 pm -
1 stop12h 59m
Deal found 9/10![Multiple Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/115:50 pm -
2 stops45h 00m
Tue 2/164:00 pm -
2 stops23h 16m
Deal found 9/11![United Airlines logo]()
$640
This Avianca deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:35 am -
2 stops12h 20m
Sat 12/511:00 pm -
1 stop10h 34m
Deal found 9/8![Multiple Airlines logo]()
$627
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:35 am -
1 stop7h 58m
Fri 11/132:30 pm -
1 stop9h 28m
Deal found 9/12![JetBlue logo]()
$628
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:59 pm -
2 stops27h 01m
Thu 10/2212:14 am -
2 stops19h 33m
Deal found 9/9![United Airlines logo]()
$643
This JetBlue deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/278:00 am -
1 stop7h 34m
Wed 3/32:25 pm -
1 stop9h 33m
Deal found 9/11![JetBlue logo]()
$641
This Avianca deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:53 pm -
1 stop11h 22m
Fri 10/2311:35 pm -
1 stop10h 13m
Deal found 9/8![Multiple Airlines logo]()
$642
This Justfly.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:45 pm -
2 stops12h 40m
Sat 1/307:30 pm -
2 stops13h 35m
Deal found 9/11![Multiple Airlines logo]()
$646
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
1 stop8h 35m
Sun 10/2512:44 pm -
1 stop10h 14m
Deal found 9/11![JetBlue logo]()
$674
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1211:20 am -
1 stop19h 35m
Mon 1/2512:05 am -
1 stop15h 00m
Deal found 9/11![LATAM Airlines logo]()
$923
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:00 am -
2 stops15h 30m
Tue 1/2611:40 pm -
2 stops13h 44m
Deal found 9/11![Delta logo]()
$970
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:29 pm -
1 stop29h 31m
Fri 10/2310:40 pm -
1 stop15h 34m
Deal found 9/11![Multiple Airlines logo]()
$677
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
2 stops26h 05m
Mon 1/2512:10 pm -
1 stop11h 45m
Deal found 9/7![LATAM Airlines logo]()
$961
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:20 pm -
1 stop12h 40m
Thu 11/1211:40 pm -
1 stop11h 31m
Deal found 9/8![Delta logo]()
$995
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:08 am -
2 stops19h 37m
Thu 11/1910:30 pm -
2 stops21h 32m
Deal found 9/10![American Airlines logo]()
$1,102
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
2 stops14h 30m
Mon 11/1612:35 pm -
2 stops22h 00m
Deal found 9/10![LATAM Airlines logo]()
$995
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:35 am -
1 stop7h 12m
Mon 11/163:52 pm -
1 stop8h 06m
Deal found 9/10![JetBlue logo]()
$874
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
2 stops14h 30m
Thu 11/1212:35 pm -
2 stops22h 00m
Deal found 9/10![LATAM Airlines logo]()
$995
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2111:24 am -
2 stops18h 11m
Sat 2/2712:05 am -
2 stops17h 54m
Deal found 9/10![American Airlines logo]()
$1,238
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops25h 35m
Mon 12/149:55 pm -
2 stops24h 49m
Deal found 9/8![United Airlines logo]()
$1,147
This JetBlue deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:10 am -
1 stop7h 50m
Fri 10/302:52 pm -
1 stop8h 06m
Deal found 9/8![JetBlue logo]()
$879
Last-minute flights from Buffalo to South AmericaDiscover last-minute flight deals from Buffalo to South America. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to South America. Data last updated September 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am -
2 stops15h 10m
Fri 9/259:45 am -
2 stops22h 44m
Deal found 9/11![United Airlines logo]()
$608
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:50 pm -
1 stop11h 25m
Wed 10/147:10 am -
1 stop10h 53m
Deal found 9/9![Multiple Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:17 pm -
2 stops20h 18m
Wed 10/141:35 pm -
2 stops22h 11m
Deal found 9/9![American Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:59 pm -
2 stops26h 11m
Fri 10/239:45 am -
2 stops22h 23m
Deal found 9/11![United Airlines logo]()
$576
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:53 pm -
2 stops17h 42m
Sun 10/251:35 pm -
2 stops20h 03m
Deal found 9/10![American Airlines logo]()
$512
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:53 pm -
1 stop11h 22m
Tue 10/271:40 pm -
1 stop9h 18m
Deal found 9/9![Multiple Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop16h 30m
Sat 10/2411:55 pm -
1 stop21h 59m
Deal found 9/8![American Airlines logo]()
$639
This Avianca deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:53 pm -
1 stop11h 22m
Fri 10/2311:35 pm -
1 stop10h 13m
Deal found 9/8![Multiple Airlines logo]()
$642
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:59 pm -
2 stops27h 01m
Thu 10/2212:14 am -
2 stops19h 33m
Deal found 9/9![United Airlines logo]()
$643
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:30 am -
2 stops15h 45m
Sun 11/110:45 am -
2 stops22h 36m
Deal found 9/10![United Airlines logo]()
$600
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
1 stop8h 21m
Thu 10/2912:44 pm -
1 stop10h 14m
Deal found 9/9![JetBlue logo]()
$488
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:35 am -
1 stop7h 12m
Wed 10/282:52 pm -
1 stop8h 06m
Deal found 9/9![JetBlue logo]()
$614
One-way flights from Buffalo to South AmericaSearch for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
2 stops17h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:30 am -
2 stops15h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:53 pm -
3 stops44h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:54 pm -
3 stops43h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:51 pm -
3 stops26h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$285
This Avianca deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:53 pm -
1 stop11h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$290
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/257:58 pm -
2 stops15h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$298
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:59 pm -
1 stop13h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:49 am -
2 stops14h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$319
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:05 am -
1 stop14h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![LATAM Airlines logo]()
$324
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop25h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:59 pm -
2 stops27h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$331
Find flight deals from Buffalo to South America
Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated September 12, 2026.
Round-trip from | $384 (American Airlines) |
|---|---|
One-way from | $170 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloMedellín
BUF Buffalo - MDE Medellín Jose Maria Cordova Intl
BUFMDE
Buffalo
Thu 11/12
6:21 pm-2:12 pm
2 stops19h 51m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
BuffaloMedellín
BUF Buffalo - MDE Medellín Jose Maria Cordova Intl
BUFMDE
Buffalo
Thu 11/5
6:30 am-10:10 pm
2 stops15h 40m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$228
BuffaloMedellín
BUF Buffalo - MDE Medellín Jose Maria Cordova Intl
BUFMDE
Buffalo
Thu 11/5
12:54 pm-8:15 am
3 stops43h 21m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$245
BuffaloMedellín
BUF Buffalo - MDE Medellín Jose Maria Cordova Intl
BUFMDE
Buffalo
Thu 11/12
7:59 pm-9:05 am
1 stop13h 06m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$304
BuffaloBogotá
BUF Buffalo - BOG Bogotá El Dorado
BUFBOG
Buffalo
Thu 2/25
6:00 am-7:30 pm
1 stop13h 30m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$324
BuffaloBogotá
BUF Buffalo - BOG Bogotá El Dorado
BUFBOG
Buffalo
Sun 10/4
6:00 am-6:15 am
1 stop25h 15m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$327
BuffaloBogotá
BUF Buffalo - BOG Bogotá El Dorado
BUFBOG
Buffalo
Sun 10/4
6:30 am-4:54 am
2 stops23h 24m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$329
BuffaloBogotá
BUF Buffalo - BOG Bogotá El Dorado
BUFBOG
Buffalo
Sat 11/21
8:55 pm-11:05 pm
1 stop26h 10m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$332
BuffaloMedellín
BUF Buffalo - MDE Medellín Jose Maria Cordova Intl
BUFMDE
Buffalo
Thu 10/15
6:47 pm-8:15 am
2 stops38h 28m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$337
BuffaloBogotá
BUF Buffalo - BOG Bogotá El Dorado
BUFBOG
Buffalo
Tue 10/13
7:59 pm-10:00 pm
2 stops27h 01m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$346
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Buffalo to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
BUF-MDE
BUF-CTG
BUF-BOG
BUF-BAQ
BUF-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to South America
BUF-0SA
BUF-MDE
BUF-CTG
BUF-BOG
BUF-BAQ
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 12, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Boarding
8.1
Crew
8.5
Overall
7.8
Food
7.2
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to South America by cabin class
Find flights from Buffalo to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and South America flights
Browse other Buffalo and South America flight options. Last updated on September 12, 2026.
Popular flight searches
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Fly to South America countries
Consider these flights traveling to countries located in South America.
Buffalo to South America flights
Consider these flights traveling from Buffalo to South America.
Top 4 airlines flying from Buffalo to South America
Discover the top 4 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$320 | Average$745 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$442 | Average$479 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$817 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,163 | Average$1,271 | FlexibilityNo cancel fee | On-time69% |