$239+ Cheap flights from Buffalo (BUF) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
Aug 21 — Aug 281
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to South America
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Cheapest flights from Buffalo to South AmericaExplore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:30 am
BUF
- MDE
2 stops35h 40m
United Airlines
Wed 9/239:45 am
MDE
- BUF
2 stops22h 44m
United Airlines
Deal found 7/19![United Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:45 pm
BUF
- MDE
2 stops28h 25m
United Airlines
Sun 10/259:45 am
MDE
- BUF
2 stops22h 44m
United Airlines
Deal found 7/19![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:58 pm
BUF
- MDE
2 stops28h 12m
United Airlines
Wed 9/169:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/17![United Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:30 am
BUF
- MDE
2 stops11h 40m
United Airlines
Thu 11/2610:40 am
MDE
- BUF
2 stops12h 49m
United Airlines
Deal found 7/20![United Airlines logo]()
$502
This Avianca deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:00 pm
BUF
- BOG
1 stop11h 15m
Multiple Airlines
Tue 9/227:10 am
BOG
- BUF
1 stop10h 51m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$528
This JetBlue deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:55 am
BUF
- CTG
1 stop7h 37m
JetBlue
Thu 9/102:00 pm
CTG
- BUF
1 stop7h 56m
JetBlue
Deal found 7/21![JetBlue logo]()
$536
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:58 pm
BUF
- MDE
2 stops28h 12m
United Airlines
Wed 9/169:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/17![United Airlines logo]()
$548
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:05 am
BUF
- MDE
2 stops14h 15m
Delta
Wed 9/1610:55 am
MDE
- BUF
2 stops29h 59m
Delta
Deal found 7/17![Delta logo]()
$557
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:05 am
BUF
- BOG
1 stop8h 35m
Delta
Tue 9/152:55 pm
BOG
- BUF
1 stop19h 17m
Delta
Deal found 7/17![Delta logo]()
$577
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:53 pm
BUF
- MDE
2 stops17h 55m
American Airlines
Sat 11/71:30 am
MDE
- BUF
2 stops14h 20m
American Airlines
Deal found 7/20![American Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:05 am
BUF
- BOG
1 stop8h 35m
Delta
Tue 9/158:40 am
BOG
- BUF
2 stops14h 14m
Delta
Deal found 7/17![Delta logo]()
$582
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:42 am
BUF
- BOG
1 stop10h 33m
Multiple Airlines
Tue 9/89:05 am
BOG
- BUF
1 stop8h 53m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$584
Best flights from Buffalo to South AmericaDiscover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
Discover carefully curated flight deals from Buffalo to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:30 am
BUF
- MDE
2 stops35h 40m
United Airlines
Wed 9/239:45 am
MDE
- BUF
2 stops22h 44m
United Airlines
Deal found 7/19![United Airlines logo]()
$386
This JetBlue deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:55 am
BUF
- CTG
1 stop7h 37m
JetBlue
Thu 9/102:00 pm
CTG
- BUF
1 stop7h 56m
JetBlue
Deal found 7/21![JetBlue logo]()
$536
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:00 am
BUF
- BOG
2 stops14h 35m
Delta
Tue 9/158:40 am
BOG
- BUF
2 stops14h 14m
Delta
Deal found 7/17![Delta logo]()
$577
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:53 pm
BUF
- MDE
2 stops17h 55m
American Airlines
Sat 11/71:30 am
MDE
- BUF
2 stops14h 20m
American Airlines
Deal found 7/20![American Airlines logo]()
$581
This Avianca deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:42 am
BUF
- BOG
1 stop10h 33m
Multiple Airlines
Tue 9/89:05 am
BOG
- BUF
1 stop8h 53m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$584
This LATAM Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 am
BUF
- MDE
2 stops18h 40m
LATAM Airlines
Wed 9/211:15 pm
MDE
- BUF
2 stops23h 44m
LATAM Airlines
Deal found 7/18![LATAM Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:45 pm
BUF
- MDE
2 stops28h 25m
United Airlines
Sun 10/259:45 am
MDE
- BUF
2 stops22h 44m
United Airlines
Deal found 7/19![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:59 pm
BUF
- MDE
2 stops26h 16m
United Airlines
Sun 11/810:40 am
MDE
- BUF
2 stops22h 49m
United Airlines
Deal found 7/20![United Airlines logo]()
$436
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:05 am
BUF
- BOG
1 stop8h 35m
Delta
Thu 9/1711:00 am
BOG
- BUF
2 stops11h 54m
Delta
Deal found 7/17![Delta logo]()
$582
This Cheapflightsfares deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:40 am
BUF
- MDE
1 stop7h 50m
JetBlue
Sun 10/251:26 pm
MDE
- BUF
1 stop9h 36m
JetBlue
Deal found 7/19![JetBlue logo]()
$586
This FlightHub deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:40 am
BUF
- MDE
1 stop7h 50m
Multiple Airlines
Sun 10/2510:45 pm
MDE
- BUF
2 stops24h 14m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$592
This Ovago deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:58 pm
BUF
- EZE
2 stops31h 32m
Copa Airlines
Mon 8/245:25 am
EZE
- BUF
2 stops29h 03m
Copa Airlines
Deal found 7/19![Copa Airlines logo]()
$1,192
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:00 am
BUF
- BOG
1 stop16h 34m
American Airlines
Tue 9/86:30 am
BOG
- BUF
2 stops14h 01m
American Airlines
Deal found 7/19![American Airlines logo]()
$601
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:58 pm
BUF
- MDE
2 stops28h 12m
United Airlines
Wed 9/169:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/17![United Airlines logo]()
$499
This LATAM Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:19 pm
BUF
- BOG
1 stop19h 21m
LATAM Airlines
Tue 8/2510:35 am
BOG
- BUF
2 stops12h 24m
LATAM Airlines
Deal found 7/19![LATAM Airlines logo]()
$622
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:00 am
BUF
- BOG
2 stops14h 35m
Delta
Sat 9/1910:35 am
BOG
- BUF
2 stops12h 19m
Delta
Deal found 7/17![Delta logo]()
$582
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am
BUF
- MDE
2 stops15h 10m
United Airlines
Wed 9/169:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/17![United Airlines logo]()
$499
This FlightHub deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:52 pm
BUF
- BOG
1 stop15h 23m
Multiple Airlines
Sat 9/129:05 am
BOG
- BUF
1 stop12h 51m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:05 am
BUF
- BOG
1 stop14h 10m
Delta
Sat 9/1910:35 am
BOG
- BUF
2 stops12h 19m
Delta
Deal found 7/17![Delta logo]()
$587
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:59 pm
BUF
- EZE
2 stops51h 26m
Avianca
Mon 9/74:50 pm
EZE
- BUF
2 stops41h 18m
Avianca
Deal found 7/19![Avianca logo]()
$1,504
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:01 pm
BUF
- CTG
2 stops18h 31m
American Airlines
Sat 11/282:35 pm
CTG
- BUF
2 stops20h 07m
American Airlines
Deal found 7/21![American Airlines logo]()
$721
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:05 am
BUF
- BOG
2 stops12h 45m
Delta
Fri 9/1811:00 am
BOG
- BUF
2 stops11h 54m
Delta
Deal found 7/17![Delta logo]()
$609
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:59 pm
BUF
- MDE
2 stops26h 11m
United Airlines
Wed 8/199:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/18![United Airlines logo]()
$590
This LATAM Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:05 am
BUF
- CTG
2 stops16h 05m
LATAM Airlines
Thu 9/102:30 pm
CTG
- BUF
1 stop8h 22m
LATAM Airlines
Deal found 7/18![LATAM Airlines logo]()
$795
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:05 am
BUF
- BOG
2 stops15h 30m
Delta
Sun 9/138:40 am
BOG
- BUF
2 stops14h 32m
Delta
Deal found 7/17![Delta logo]()
$609
This Justfly.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:40 am
BUF
- CTG
1 stop7h 52m
JetBlue
Thu 8/62:55 pm
CTG
- BUF
1 stop8h 18m
JetBlue
Deal found 7/20![JetBlue logo]()
$872
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:05 am
BUF
- BOG
1 stop8h 35m
Delta
Sat 9/1211:00 am
BOG
- BUF
2 stops20h 24m
Delta
Deal found 7/18![Delta logo]()
$609
This LATAM Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:13 pm
BUF
- UIO
2 stops43h 32m
Multiple Airlines
Mon 9/76:30 pm
UIO
- BUF
2 stops24h 56m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$811
This oojo deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:15 pm
BUF
- LIM
2 stops29h 25m
LATAM Airlines
Wed 9/2312:15 am
LIM
- BUF
2 stops22h 39m
LATAM Airlines
Deal found 7/18![LATAM Airlines logo]()
$847
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:05 am
BUF
- BOG
2 stops15h 05m
Delta
Tue 8/2511:00 am
BOG
- BUF
2 stops21h 13m
Delta
Deal found 7/19![Delta logo]()
$622
Last-minute flights from Buffalo to South AmericaDiscover last-minute flight deals from Buffalo to South America. Data last updated July 22, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to South America. Data last updated July 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:48 pm
BUF
- CTG
2 stops20h 47m
American Airlines
Wed 7/291:35 pm
CTG
- BUF
2 stops19h 41m
American Airlines
Deal found 7/21![American Airlines logo]()
$630
This FlightHub deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:19 pm
BUF
- CTG
1 stop18h 56m
LATAM Airlines
Thu 8/132:30 pm
CTG
- BUF
1 stop8h 29m
LATAM Airlines
Deal found 7/21![LATAM Airlines logo]()
$683
This Orbitz deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:02 pm
BUF
- BOG
2 stops20h 58m
Multiple Airlines
Thu 8/139:05 am
BOG
- BUF
1 stop9h 20m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$675
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:59 pm
BUF
- MDE
2 stops26h 11m
United Airlines
Wed 8/199:45 am
MDE
- BUF
2 stops22h 43m
United Airlines
Deal found 7/20![United Airlines logo]()
$590
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:26 am
BUF
- MDE
1 stop8h 19m
Multiple Airlines
Wed 8/194:55 pm
MDE
- BUF
1 stop13h 41m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$617
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:02 pm
BUF
- BOG
1 stop11h 13m
Multiple Airlines
Tue 8/259:05 am
BOG
- BUF
1 stop9h 20m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:05 am
BUF
- BOG
2 stops15h 05m
Delta
Tue 8/2511:00 am
BOG
- BUF
2 stops21h 13m
Delta
Deal found 7/19![Delta logo]()
$622
This LATAM Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 am
BUF
- MDE
2 stops18h 40m
LATAM Airlines
Wed 9/211:15 pm
MDE
- BUF
2 stops23h 44m
LATAM Airlines
Deal found 7/18![LATAM Airlines logo]()
$593
This FlightHub deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:55 am
BUF
- BOG
1 stop14h 35m
Multiple Airlines
Mon 9/72:40 pm
BOG
- BUF
1 stop27h 18m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$624
This Avianca deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:26 am
BUF
- MDE
1 stop8h 19m
Multiple Airlines
Wed 9/27:05 am
MDE
- BUF
2 stops12h 04m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:00 am
BUF
- BOG
1 stop16h 34m
American Airlines
Mon 9/76:30 am
BOG
- BUF
2 stops16h 26m
American Airlines
Deal found 7/20![American Airlines logo]()
$643
This Vliegwinkel deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:59 pm
BUF
- BOG
1 stop10h 16m
Multiple Airlines
Mon 9/74:05 pm
BOG
- BUF
1 stop16h 36m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$589
One-way flights from Buffalo to South AmericaSearch for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
Search for one-way flight options from Buffalo to South America. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:18 pm
BUF
- CTG
2 stops20h 17m
American Airlines
Deal found 7/19![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:16 pm
BUF
- BOG
2 stops29h 34m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$256
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:00 pm
BUF
- MDE
1 stop12h 05m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:43 am
BUF
- BOG
2 stops11h 34m
American Airlines
Deal found 7/19![American Airlines logo]()
$279
This Justfly.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:57 am
BUF
- BOG
1 stop9h 48m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2311:36 am
BUF
- GRU
3 stops44h 04m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$305
This Travelocity deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:59 pm
BUF
- BOG
1 stop26h 31m
LATAM Airlines
Deal found 7/18![LATAM Airlines logo]()
$310
This Avianca deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:00 pm
BUF
- BOG
2 stops14h 50m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$320
This FlightHub deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:13 pm
BUF
- BOG
2 stops25h 37m
LATAM Airlines
Deal found 7/19![LATAM Airlines logo]()
$340
This KAYAK deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:01 pm
BUF
- BOG
2 stops19h 13m
GOL
Deal found 7/21![GOL logo]()
$354
This FlightHub deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am
BUF
- MDE
2 stops16h 05m
LATAM Airlines
Deal found 7/21![LATAM Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:16 pm
BUF
- CTG
3 stops22h 44m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$371
Find flight deals from Buffalo to South America
Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated July 22, 2026.
Round-trip from | $386 (United Airlines) |
|---|---|
One-way from | $239 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Thu 9/17
10:30 am-9:10 pm
2 stops35h 40m
Medellín Jose Maria Cordova Intl
Wed 9/23
9:45 am-9:29 am
2 stops22h 44m
$386
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Fri 10/16
5:45 pm-9:10 pm
2 stops28h 25m
Medellín Jose Maria Cordova Intl
Sun 10/25
9:45 am-9:29 am
2 stops22h 44m
$436
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Fri 10/30
7:59 pm-9:15 pm
2 stops26h 16m
Medellín Jose Maria Cordova Intl
Sun 11/8
10:40 am-9:29 am
2 stops22h 49m
$436
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Sun 9/6
5:58 pm-9:10 pm
2 stops28h 12m
Medellín Jose Maria Cordova Intl
Wed 9/16
9:45 am-9:28 am
2 stops22h 43m
$499
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Tue 9/8
7:00 am-9:10 pm
2 stops15h 10m
Medellín Jose Maria Cordova Intl
Wed 9/16
9:45 am-9:28 am
2 stops22h 43m
$499
Quickest round-trip
BuffaloCartagena
BUF - CTG
BUFCTG
Buffalo
Sun 9/6
6:55 am-1:32 pm
1 stop7h 37m
Cartagena Rafael Nunez
Thu 9/10
2:00 pm-10:56 pm
1 stop7h 56m
$536
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Mon 9/7
7:00 am-8:35 pm
2 stops14h 35m
Bogotá El Dorado
Tue 9/15
8:40 am-11:54 pm
2 stops14h 14m
$577
BuffaloMedellín
BUF - MDE
BUFMDE
Buffalo
Fri 10/30
7:53 pm-12:48 pm
2 stops17h 55m
Medellín Jose Maria Cordova Intl
Sat 11/7
1:30 am-3:50 pm
2 stops14h 20m
$581
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Sun 9/6
6:05 am-1:40 pm
1 stop8h 35m
Bogotá El Dorado
Thu 9/17
11:00 am-11:54 pm
2 stops11h 54m
$582
BuffaloBogotá
BUF - BOG
BUFBOG
Buffalo
Mon 9/7
7:00 am-8:35 pm
2 stops14h 35m
Bogotá El Dorado
Sat 9/19
10:35 am-11:54 pm
2 stops12h 19m
$582
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Buffalo to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
BUF-BOG
BUF-MDE
BUF-CTG
BUF-UIO
BUF-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to South America
BUF-0SA
BUF-BOG
BUF-MDE
BUF-CTG
BUF-UIO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 22, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Buffalo to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to South America by cabin class
Find flights from Buffalo to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and South America flights
Browse other Buffalo and South America flight options. Last updated on July 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Buffalo to South America flights
Consider these flights traveling from Buffalo to South America.
Top 4 airlines flying from Buffalo to South America
Discover the top 4 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$320 | Average$735 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$442 | Average$479 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$587 | Average$809 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,163 | Average$1,271 | FlexibilityNo cancel fee | On-time69% |