Santa Ana

$85+ Cheap flights from Des Moines to Santa Ana, CA (DSM - SNA)

DSM — SNA
Nov 29 — Dec 61
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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Des Moines to Santa Ana J. Wayne/Orange Cnty are usually found in January or September, booked 33 days in advance, depart on a Monday or Sunday and return on a Monday

Cheap flight deals from Des Moines to Santa Ana

Cheapest flights from Des Moines to Santa Ana

Mon 11/232:50 pm -
Nonstop3h 44m
Thu 12/33:39 pm -
1 stop26h 49m
Deal found 10/28$192
Mon 11/232:50 pm -
Nonstop3h 44m
Wed 11/255:24 pm -
Nonstop3h 15m
Deal found 10/27$215
Mon 11/232:50 pm -
Nonstop3h 44m
Thu 11/2611:42 am -
1 stop5h 51m
Deal found 10/27$219
Wed 11/252:50 pm -
Nonstop3h 44m
Thu 12/33:39 pm -
1 stop26h 49m
Deal found 10/28$221
Fri 11/202:50 pm -
Nonstop3h 44m
Thu 12/33:39 pm -
1 stop26h 49m
Deal found 10/28$232
Fri 11/202:50 pm -
Nonstop3h 44m
Wed 11/255:24 pm -
Nonstop3h 15m
Deal found 10/28$235
Wed 11/252:50 pm -
Nonstop3h 44m
Thu 11/2611:42 am -
1 stop5h 51m
Deal found 10/27$238
Sun 11/223:00 pm -
2 stops20h 22m
Thu 12/33:39 pm -
1 stop26h 49m
Deal found 10/28$245
Thu 11/52:22 pm -
Nonstop3h 38m
Sun 11/84:10 pm -
Nonstop3h 17m
Deal found 10/28$251

Find flight deals from Des Moines to Santa Ana

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$119
(Cheapflightsfares)

One-way from

$85
(CheapOair)

Popular in

March

Cheapest in

January

Average price

$227

Good round-trip deal

$258 or less

Good one-way deal

$162 or less
Provider with most accurate pricing for Des Moines-Santa Ana J. Wayne/Orange Cnty flight deals.
Provider most trusted by Cheapflights users for Des Moines-Santa Ana J. Wayne/Orange Cnty flights.
From Des Moines to Santa Ana J. Wayne/Orange Cnty
One-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty
Highest demand for flights based on searches. 18% potential increase in price ($75 potential increase over avg. RT price).
Cheapest flight prices on average. 8% potential price decrease ($24 potential savings vs. average RT price).
Average for round-trip flights in October 2026
Price to beat on a round-trip flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Price to beat on a one-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Wed 11/25

2:50 pm-4:34 pm

Nonstop3h 44m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

12:00 am-2:00 am

Nonstop0h 00m

$91

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Wed 1/20

5:07 pm-10:14 pm

1 stop7h 07m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

12:00 am-2:00 am

Nonstop0h 00m

$180

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Fri 1/8

10:54 am-10:28 pm

2 stops13h 34m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

12:00 am-2:00 am

Nonstop0h 00m

$190

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Tue 1/19

11:22 am-8:44 pm

2 stops11h 22m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

12:00 am-2:00 am

Nonstop0h 00m

$190

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Wed 11/25

5:09 pm-10:00 pm

1 stop6h 51m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

12:00 am-2:00 am

Nonstop0h 00m

$228

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Wed 3/10

6:55 am-10:20 am

1 stop5h 25m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

12:00 am-2:00 am

Nonstop0h 00m

$239

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Tue 1/5

6:30 pm-9:45 pm

1 stop5h 15m

Santa Ana J. Wayne/Orange Cnty

Tue 2/23

11:00 am-8:35 pm

2 stops7h 35m

$374

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Fri 1/8

6:55 am-1:15 pm

2 stops8h 20m

Santa Ana J. Wayne/Orange Cnty

Mon 1/11

11:00 am-8:35 pm

2 stops7h 35m

$399

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Sat 11/21

5:09 pm-9:19 pm

1 stop6h 10m

Santa Ana J. Wayne/Orange Cnty

Tue 12/1

8:55 am-4:13 pm

1 stop5h 18m

$415

Des MoinesSanta Ana

DSM Des Moines - SNA Santa Ana J. Wayne/Orange Cnty

DSMSNA

Des Moines

Sun 11/22

2:48 pm-8:55 pm

1 stop8h 07m

Santa Ana J. Wayne/Orange Cnty

Tue 12/1

9:53 am-9:31 pm

2 stops9h 38m

$431

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 18 resultsSorted by cheapest first
1
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Compare providers for flights from Des Moines to Santa Ana

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santa Ana in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
CheapTicketsDealPrice Accuracy1 starTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*1 star
WAYAPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Des Moines with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Santa Ana

How far ahead should I book a flight from Des Moines to Santa Ana, California?

To ensure you get the cheapest price possible for a flight from Des Moines to Santa Ana, California, you should look to book at least 23 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Santa Ana, California?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $158). Flying from Des Moines to Santa Ana, California in March is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Santa Ana, California?

Airfare is below average for this route at the moment.

Des Moines to Santa Ana, California flights typically cost between $333 and $466 in January.
The cheapest round-trip price found within the last 5 days was $119 on Allegiant Air (Jan 18-Feb 5).

Reviews of airlines servicing Santa Ana

Read through reviews of airlines operating flights from Des Moines to Santa Ana, such as Southwest,United Airlines, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.4

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Entertainment

7.4

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Entertainment

7.4

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Entertainment

7.4

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Entertainment

7.4

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Related info for your journey

  • How popular is this Des Moines to Santa Ana, California flight route?

  • How long is the flight from Des Moines to Santa Ana, California?

    There are many flights that can get you from Des Moines to Santa Ana, California in 5h 15m. Fly via Southwest, United Airlines, or Delta to get the fastest option. Des Moines and Santa Ana, California are separated by a distance of 1425 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Santa Ana, California round-trip?

    Our cheapest airline available from Des Moines to Santa Ana, California is Allegiant Air. Our recent data shows that you can find tickets from as low as $124 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $268 and $292 round-trip. Allegiant Air is 61% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Des Moines to Santa Ana, California one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $73. American Airlines flights start at $130 while deals on United Airlines start at $173 one-way.

  • What are the cheapest flights from Des Moines to Santa Ana, California?

    On average you can expect to pay $264 for a flight from Des Moines to Santa Ana, California. The cheapest flight overall is $100 while the most popular route, (Des Moines - Santa Ana J. Wayne/Orange Cnty) is currently priced at $163.

  • Can I find deals for flights from Des Moines to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Santa Ana.

  • Can I find deals for business class flights from Des Moines to Santa Ana?

    Yes. Cheapflights offers flight deals from Des Moines to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Santa Ana, California?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $158). Flying from Des Moines to Santa Ana, California in March is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Top 4 airlines flying from Des Moines to Santa Ana

AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$124Average$226FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$268Average$416FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$292Average$398FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$294Average$476FlexibilityNo cancel feeOn-time63%

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