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Santa Ana

$77+ Cheap flights from Des Moines to Santa Ana, CA (DSM - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SNA
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Des Moines to Santa Ana J. Wayne/Orange Cnty are usually found in September or January, booked 30 days in advance, depart on a Friday or Saturday and return on a Monday

Cheap flight deals from Des Moines to Santa Ana

Cheapest flights from Des Moines to Santa Ana
Explore the most affordable flight options available from Des Moines to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This Booking.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:15 am
DSM
-
SNA
Nonstop4h 00m
Allegiant Air
Fri 2/2010:05 am
SNA
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/18$114
This Booking.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
-
SNA
Nonstop3h 58m
Allegiant Air
Fri 3/69:45 am
SNA
-
DSM
Nonstop3h 16m
Allegiant Air
Deal found 1/17$128
This Booking.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:50 am
DSM
-
SNA
Nonstop3h 51m
Allegiant Air
Fri 4/1712:41 pm
SNA
-
DSM
Nonstop3h 17m
Allegiant Air
Deal found 1/18$136
This Gotogate deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/87:00 am
DSM
-
SNA
Nonstop3h 47m
Allegiant Air
Fri 2/1310:05 am
SNA
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/19$142
This Booking.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:00 am
DSM
-
SNA
Nonstop3h 51m
Allegiant Air
Mon 4/610:41 am
SNA
-
DSM
Nonstop3h 17m
Allegiant Air
Deal found 1/17$156
This Flightnetwork deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:00 am
DSM
-
SNA
Nonstop3h 55m
Allegiant Air
Fri 3/139:45 am
SNA
-
DSM
Nonstop3h 16m
Allegiant Air
Deal found 1/20$163
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:21 pm
DSM
-
SNA
1 stop16h 26m
Multiple Airlines
Fri 3/139:45 am
SNA
-
DSM
Nonstop3h 16m
Multiple Airlines
Deal found 1/20$166
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:17 pm
DSM
-
SNA
2 stops19h 08m
Multiple Airlines
Fri 2/2010:05 am
SNA
-
DSM
Nonstop3h 19m
Multiple Airlines
Deal found 1/18$173
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/57:00 am
DSM
-
SNA
Nonstop3h 47m
Allegiant Air
Fri 2/1310:05 am
SNA
-
DSM
Nonstop3h 19m
Allegiant Air
Deal found 1/19$176
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
-
SNA
2 stops22h 25m
Multiple Airlines
Fri 3/69:45 am
SNA
-
DSM
Nonstop3h 16m
Multiple Airlines
Deal found 1/17$178

Find flight deals from Des Moines to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$114
(Booking.com)

One-way from

$77
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$178

Good round-trip deal

$137 or less

Good one-way deal

$128 or less
Provider with most accurate pricing for Des Moines-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Search Deals
Price to beat on a one-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Des Moines to Santa Ana that are best for you.

Fly from

Des Moines

Fly to

Santa Ana

Route

Depart

Return

Price

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Mon 3/2

7:15 am-9:13 am

Nonstop3h 58m

Santa Ana J. Wayne/Orange Cnty

Fri 3/6

9:45 am-3:01 pm

Nonstop3h 16m

$128

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 2/8

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Fri 2/13

10:05 am-3:24 pm

Nonstop3h 19m

$142

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 3/6

7:00 am-8:55 am

Nonstop3h 55m

Santa Ana J. Wayne/Orange Cnty

Fri 3/13

9:45 am-3:01 pm

Nonstop3h 16m

$163

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 3/5

7:27 pm-10:47 am

1 stop17h 20m

Santa Ana J. Wayne/Orange Cnty

Thu 3/12

4:37 pm-10:34 pm

1 stop27h 57m

$198

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Mon 4/13

3:32 pm-8:56 pm

1 stop7h 24m

Santa Ana J. Wayne/Orange Cnty

Fri 4/17

12:41 pm-5:58 pm

Nonstop3h 17m

$220

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 3/6

8:21 pm-10:47 am

1 stop16h 26m

Santa Ana J. Wayne/Orange Cnty

Fri 3/13

11:32 am-7:16 pm

1 stop5h 44m

$229

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 2/8

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Fri 2/13

6:45 am-10:51 pm

1 stop14h 06m

$235

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 1/29

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Sun 2/1

9:37 am-3:03 pm

Nonstop3h 26m

$250

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 2/25

5:00 am-10:51 am

1 stop7h 51m

Santa Ana J. Wayne/Orange Cnty

Tue 3/3

3:23 pm-11:40 pm

1 stop6h 17m

$261

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 3/6

8:21 pm-8:57 pm

3 stops26h 36m

Santa Ana J. Wayne/Orange Cnty

Fri 3/13

9:45 am-3:01 pm

Nonstop3h 16m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 20 results
1
2

Compare providers for flights from Des Moines to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santa Ana in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Santa Ana, California flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Santa Ana

How far ahead should I book a flight from Des Moines to Santa Ana, California?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Santa Ana. Price data was last updated on January 16, 2026.

To ensure you get the cheapest price possible for a flight from Des Moines to Santa Ana, California, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $101). Flying from Des Moines to Santa Ana, California in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated January 20, 2026.
Read through reviews of airlines operating flights from Des Moines to Santa Ana, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,080 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,183 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,163 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Allegiant Air
7.2
Good
705 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Santa Ana, California flight route?

    The Des Moines to Santa Ana J. Wayne/Orange Cnty flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to Santa Ana, California?

    There are many flights that can get you from Des Moines to Santa Ana, California in 3h 58m. Fly via Allegiant Air to get the fastest option. Des Moines and Santa Ana, California are separated by a distance of 1425 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Des Moines to Santa Ana, California round-trip?

    Our cheapest airline available from Des Moines to Santa Ana, California is Allegiant Air. Our recent data shows that you can find tickets from as low as $106 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $130 and $260 round-trip. Allegiant Air is 65% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Des Moines to Santa Ana, California one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $64. American Airlines flights start at $130 while deals on Southwest start at $143 one-way.

  • What are the cheapest flights from Des Moines to Santa Ana, California?

    On average you can expect to pay $214 for a flight from Des Moines to Santa Ana, California. The cheapest flight overall is $126 while the most popular route, (Des Moines - Santa Ana J. Wayne/Orange Cnty) is currently priced at $136.

  • Can I find deals for flights from Des Moines to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Santa Ana.

  • Can I find deals for business class flights from Des Moines to Santa Ana?

    Yes. Cheapflights offers flight deals from Des Moines to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $101). Flying from Des Moines to Santa Ana, California in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
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Alternative routes for Des Moines to Santa Ana

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Top 5 airlines flying from Des Moines to Santa Ana

Discover the top 5 airlines that operate flights from Des Moines to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$106Average$183FlexibilityNo cancel feeOn-time88%
DeltaCheapest$130Average$273FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$260Average$433FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$340Average$483FlexibilityNo cancel feeOn-time63%

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