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$97+ Cheap flights from Des Moines to Santa Ana (DSM - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SNA
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Santa Ana J. Wayne/Orange Cnty are usually found in September or February, booked 22 days in advance, depart on a Sunday or Monday and return on a Wednesday

Cheap flight deals from Des Moines to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$142
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$333

Good round-trip deal

$128 or less
Provider with most accurate pricing for Des Moines-Santa Ana J. Wayne/Orange Cnty flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Santa Ana J. Wayne/Orange Cnty flights.
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From Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
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Price to beat on a round-trip flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
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Find flight deals from Des Moines to Santa Ana

Cheapest flights from Des Moines to Santa Ana
Explore the most affordable flight options available from Des Moines to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:00 amDSM - SNA
Nonstop3h 47mAllegiant Air
Sun 8/249:37 amSNA - DSM
Nonstop3h 18mAllegiant Air
Deal found 4/30$155
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/127:00 amDSM - SNA
Nonstop3h 34mMultiple Airlines
Thu 6/265:22 pmSNA - DSM
1 stop17h 12mMultiple Airlines
Deal found 4/29$208
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/115:00 amDSM - SNA
1 stop6h 20mAmerican Airlines
Tue 6/172:40 pmSNA - DSM
1 stop7h 26mAmerican Airlines
Deal found 4/29$299
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/96:00 amDSM - SNA
2 stops8h 07mUnited Airlines
Wed 7/232:02 pmSNA - DSM
1 stop6h 58mUnited Airlines
Deal found 4/29$304
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2312:15 pmDSM - SNA
1 stop6h 25mSouthwest
Thu 9/256:45 amSNA - DSM
1 stop8h 00mSouthwest
Deal found 4/29$344
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/65:35 amDSM - SNA
1 stop9h 30mDelta
Mon 6/96:59 pmSNA - DSM
2 stops13h 20mDelta
Deal found 4/29$420
This Alaska Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/62:10 pmDSM - SNA
2 stops21h 34mAlaska Airlines
Mon 6/96:45 amSNA - DSM
2 stops15h 14mAlaska Airlines
Deal found 4/29$537

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Des Moines to Santa Ana that are best for you.

Fly from

Des Moines

Fly to

Santa Ana

Route

Depart

Return

Price

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 5/15

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Sun 5/18

9:37 am-2:55 pm

Nonstop3h 18m

$156

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 6/12

7:00 am-8:34 am

Nonstop3h 34m

Santa Ana J. Wayne/Orange Cnty

Thu 6/26

5:22 pm-12:34 pm

1 stop17h 12m

$208

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 6/11

5:00 am-9:20 am

1 stop6h 20m

Santa Ana J. Wayne/Orange Cnty

Tue 6/17

2:40 pm-12:06 am

1 stop7h 26m

$299

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 7/9

6:00 am-12:07 pm

2 stops8h 07m

Santa Ana J. Wayne/Orange Cnty

Wed 7/23

2:02 pm-11:00 pm

1 stop6h 58m

$304

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 7/9

1:45 pm-8:05 pm

2 stops8h 20m

Santa Ana J. Wayne/Orange Cnty

Wed 7/23

12:35 pm-11:15 pm

2 stops8h 40m

$383

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 6/6

5:35 am-1:05 pm

1 stop9h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 6/9

6:59 pm-10:19 am

2 stops13h 20m

$420

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 6/6

2:10 pm-9:44 am

2 stops21h 34m

Santa Ana J. Wayne/Orange Cnty

Mon 6/9

6:45 am-11:59 pm

2 stops15h 14m

$537

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 5/7

7:30 pm-11:24 am

1 stop17h 54m

$97

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 6/26

5:00 am-9:25 am

1 stop6h 25m

$179

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 6/26

6:00 am-12:07 pm

2 stops8h 07m

$248

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 11 results
1
2

Compare providers for flights from Des Moines to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santa Ana in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Santa Ana flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Santa Ana flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Santa Ana flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Santa Ana flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santa Ana flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Santa Ana

How far ahead should I book a flight from Des Moines to Santa Ana?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Santa Ana. Price data was last updated on April 25, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Santa Ana, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Santa Ana (average of $298). Flying from Des Moines to Santa Ana in June is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SNA?

Find hourly flight availability from Des Moines to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Santa Ana at noon. If you’re flexible enough to do this you can expect to save up to 38% on your trip compared to booking a flight in the morning.

Rainfall in Santa Ana by month

Plan your trip to Santa Ana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santa Ana ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana when rainfall is around 0.0 in.

Temperature in Santa Ana by month

Plan your trip to Santa Ana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santa Ana, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated May 1, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Des Moines to Santa Ana to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,972 reviews

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,972 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,294 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,934 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Santa Ana flight route?

    This flight path from Des Moines to Santa Ana J. Wayne/Orange Cnty was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Des Moines to Santa Ana round-trip?

    According to our current data, Allegiant Air ($142), American Airlines ($299), and United Airlines ($304) offers the cheapest pricing from Des Moines to Santa Ana. Allegiant Air is currently priced 53% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Santa Ana one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $150. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Des Moines to Santa Ana for a low price.

  • What are the cheapest flights from Des Moines to Santa Ana?

    On average you can expect to pay $187 for a flight from Des Moines to Santa Ana. The cheapest flight overall is $108 while the most popular route, (Des Moines - Santa Ana J. Wayne/Orange Cnty) is currently priced at $142.

  • Can I find deals for flights from Des Moines to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Santa Ana.

  • Can I find deals for business class flights from Des Moines to Santa Ana?

    Yes. Cheapflights offers flight deals from Des Moines to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Santa Ana (average of $298). Flying from Des Moines to Santa Ana in June is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
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Top 4 airlines flying from Des Moines to Santa Ana

Discover the top 4 airlines that operate flights from Des Moines to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$108Average$222FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$298Average$406FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$316Average$482FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$397Average$496FlexibilityNo cancel feeOn-time63%

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