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$80+ Cheap flights from Des Moines to Santa Ana, CA (DSM - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SNA
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Santa Ana J. Wayne/Orange Cnty are usually found in September or April, booked 76 days in advance, depart on a Sunday or Friday and return on a Monday

Cheap flight deals from Des Moines to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$164
(Cheapflightsfares)

One-way from

$118
(Trip.com)

Popular in

March

Cheapest in

September

Average price

$356

Good round-trip deal

$166 or less
Provider with most accurate pricing for Des Moines-Santa Ana J. Wayne/Orange Cnty flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Santa Ana J. Wayne/Orange Cnty flights.
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From Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
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Find flight deals from Des Moines to Santa Ana

Cheapest flights from Des Moines to Santa Ana
Explore the most affordable flight options available from Des Moines to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Booking.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:00 amDSM - SNA
Nonstop3h 47mAllegiant Air
Sun 11/239:37 amSNA - DSM
Nonstop3h 17mAllegiant Air
Deal found 11/6$224
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:30 amDSM - SNA
1 stop12h 42mMultiple Airlines
Sun 12/2810:35 amSNA - DSM
2 stops31h 09mMultiple Airlines
Deal found 11/5$253
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:00 amDSM - SNA
Nonstop3h 47mMultiple Airlines
Sun 11/235:46 pmSNA - DSM
1 stop26h 59mMultiple Airlines
Deal found 11/6$283
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/262:00 pmDSM - SNA
1 stop23h 19mMultiple Airlines
Mon 12/111:37 amSNA - DSM
Nonstop3h 17mMultiple Airlines
Deal found 11/4$313
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:48 pmDSM - SNA
1 stop22h 44mMultiple Airlines
Tue 11/2510:07 amSNA - DSM
Nonstop3h 17mMultiple Airlines
Deal found 11/6$328

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to Santa Ana that are best for you.

Fly from

Des Moines

Fly to

Santa Ana

Route

Depart

Return

Price

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 2/8

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Thu 2/12

12:12 pm-11:09 pm

2 stops32h 57m

$217

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 12/21

8:30 am-7:12 pm

1 stop12h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 12/28

10:35 am-7:44 pm

2 stops31h 09m

$261

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 11/26

2:00 pm-11:19 am

1 stop23h 19m

Santa Ana J. Wayne/Orange Cnty

Mon 12/1

11:37 am-4:54 pm

Nonstop3h 17m

$313

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 1/15

3:35 pm-10:24 pm

1 stop8h 49m

Santa Ana J. Wayne/Orange Cnty

Sun 1/18

10:00 am-9:50 pm

2 stops9h 50m

$328

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 11/20

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Sun 11/23

10:07 am-9:09 pm

3 stops33h 02m

$336

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 11/26

2:00 pm-11:19 am

1 stop23h 19m

Santa Ana J. Wayne/Orange Cnty

Sun 11/30

1:27 pm-11:26 am

1 stop19h 59m

$376

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Mon 12/22

3:14 pm-10:30 pm

1 stop9h 16m

Santa Ana J. Wayne/Orange Cnty

Wed 12/31

4:15 pm-11:58 pm

1 stop5h 43m

$403

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 2/5

7:00 am-8:47 am

Nonstop3h 47m

$80

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 2/5

4:30 pm-11:17 am

2 stops20h 47m

$157

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 2/6

6:54 am-12:42 pm

1 stop7h 48m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 16 results
1
2

Compare providers for flights from Des Moines to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santa Ana in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Santa Ana

How far ahead should I book a flight from Des Moines to Santa Ana, California?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Santa Ana. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Santa Ana, California, you should look to book at least 76 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $101). Flying from Des Moines to Santa Ana, California in July is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SNA?

Find hourly flight availability from Des Moines to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Santa Ana, California as you normally would.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from Des Moines to Santa Ana, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,007 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Allegiant Air
7.2
Good
697 reviews
Southwest
8.0
Very good
4,241 reviews

Food

7.0

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Santa Ana, California flight route?

    The Des Moines to Santa Ana J. Wayne/Orange Cnty flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Des Moines to Santa Ana, California round-trip?

    Our cheapest airline available from Des Moines to Santa Ana, California is Allegiant Air. Our recent data shows that you can find tickets from as low as $108 on this airline. Additional options worth looking into are Delta and American Airlines, starting at $130 and $286 round-trip. Allegiant Air is 66% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Des Moines to Santa Ana, California one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $80. Delta flights start at $171 while deals on United Airlines start at $171 one-way.

  • What are the cheapest flights from Des Moines to Santa Ana, California?

    On average you can expect to pay $214 for a flight from Des Moines to Santa Ana, California. The cheapest flight overall is $117 while the most popular route, (Des Moines - Santa Ana J. Wayne/Orange Cnty) is currently priced at $164.

  • Can I find deals for flights from Des Moines to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Santa Ana.

  • Can I find deals for business class flights from Des Moines to Santa Ana?

    Yes. Cheapflights offers flight deals from Des Moines to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Santa Ana, California?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $101). Flying from Des Moines to Santa Ana, California in July is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Des Moines to Santa Ana

Discover the top 5 airlines that operate flights from Des Moines to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$108Average$213FlexibilityNo cancel feeOn-time88%
DeltaCheapest$130Average$326FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$454FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$340Average$483FlexibilityNo cancel feeOn-time63%

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