$91+ Cheap flights from Des Moines to Santa Ana, CA (DSM - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SNA
Mar 6 — Mar 131
1 adult, Economy
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Find cheap flights from Des Moines to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Santa Ana J. Wayne/Orange Cnty are usually found in September or January, booked 30 days in advance, depart on a Wednesday or Sunday and return on a Monday
Cheap flight deals from Des Moines to Santa Ana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Santa AnaExplore the most affordable flight options available from Des Moines to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Des Moines to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- SNA
Nonstop3h 58m
Allegiant Air
Fri 3/69:45 am
SNA
- DSM
Nonstop3h 16m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$150
This Booking.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- SNA
Nonstop3h 58m
Allegiant Air
Fri 3/139:45 am
SNA
- DSM
Nonstop3h 16m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$172
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
DSM
- SNA
Nonstop3h 55m
Allegiant Air
Fri 3/279:45 am
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 2/3![Allegiant Air logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- SNA
Nonstop3h 58m
Multiple Airlines
Fri 3/136:45 am
SNA
- DSM
1 stop26h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$207
This Booking.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:00 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Mon 4/610:41 am
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 2/3![Allegiant Air logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
DSM
- SNA
Nonstop3h 55m
Multiple Airlines
Fri 3/273:21 pm
SNA
- DSM
2 stops25h 55m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
- SNA
3 stops27h 40m
Multiple Airlines
Fri 3/69:45 am
SNA
- DSM
Nonstop3h 16m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$246
Best flights from Des Moines to Santa AnaDiscover carefully curated flight deals from Des Moines to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Des Moines to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:22 pm
DSM
- SNA
1 stop15h 31m
Multiple Airlines
Fri 3/273:21 pm
SNA
- DSM
2 stops25h 55m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:15 am
DSM
- SNA
Nonstop4h 00m
Allegiant Air
Mon 2/2310:05 am
SNA
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 2/3![Allegiant Air logo]()
$276
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:55 am
DSM
- SNA
2 stops8h 35m
Southwest
Sat 4/258:00 am
SNA
- DSM
2 stops8h 00m
Southwest
Deal found 2/3![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:23 pm
DSM
- SNA
1 stop6h 34m
Delta
Fri 5/811:48 am
SNA
- DSM
1 stop6h 48m
Delta
Deal found 2/2![Delta logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:45 am
DSM
- SNA
Nonstop3h 51m
Multiple Airlines
Sun 4/268:20 pm
SNA
- DSM
2 stops15h 09m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2810:00 am
DSM
- SNA
1 stop24h 50m
Multiple Airlines
Mon 3/309:45 am
SNA
- DSM
Nonstop3h 17m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 pm
DSM
- SNA
1 stop5h 20m
Southwest
Fri 4/248:50 am
SNA
- DSM
1 stop4h 40m
Southwest
Deal found 2/3![Southwest logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:27 pm
DSM
- SNA
1 stop17h 19m
Multiple Airlines
Mon 3/99:45 am
SNA
- DSM
Nonstop3h 16m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:17 pm
DSM
- SNA
2 stops22h 25m
Multiple Airlines
Mon 2/2310:05 am
SNA
- DSM
Nonstop3h 19m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:32 pm
DSM
- SNA
1 stop17h 14m
Multiple Airlines
Mon 2/2310:05 am
SNA
- DSM
Nonstop3h 19m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
DSM
- SNA
Nonstop3h 55m
Multiple Airlines
Mon 3/2311:32 am
SNA
- DSM
1 stop5h 44m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$388
Last-minute flights from Des Moines to Santa AnaDiscover last-minute flight deals from Des Moines to Santa Ana. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Santa Ana. Data last updated February 4, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- SNA
Nonstop3h 58m
Allegiant Air
Fri 3/69:45 am
SNA
- DSM
Nonstop3h 16m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$150
This Booking.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- SNA
Nonstop3h 58m
Allegiant Air
Fri 3/139:45 am
SNA
- DSM
Nonstop3h 16m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:15 am
DSM
- SNA
Nonstop3h 58m
Multiple Airlines
Fri 3/136:45 am
SNA
- DSM
1 stop26h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
- SNA
3 stops27h 40m
Multiple Airlines
Fri 3/69:45 am
SNA
- DSM
Nonstop3h 16m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$246
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
DSM
- SNA
Nonstop3h 55m
Allegiant Air
Fri 3/279:45 am
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 2/3![Allegiant Air logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
DSM
- SNA
Nonstop3h 55m
Multiple Airlines
Fri 3/273:21 pm
SNA
- DSM
2 stops25h 55m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$241
One-way flights from Des Moines to Santa AnaSearch for one-way flight options from Des Moines to Santa Ana. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Des Moines to Santa Ana. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/87:00 am
DSM
- SNA
Nonstop3h 47m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:45 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Deal found 2/2![Allegiant Air logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:20 pm
DSM
- SNA
1 stop23h 05m
Frontier
Deal found 2/2![Frontier logo]()
$139
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:00 am
DSM
- SNA
1 stop5h 50m
American Airlines
Deal found 2/3![American Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/281:29 pm
DSM
- SNA
2 stops9h 21m
United Airlines
Deal found 2/3![United Airlines logo]()
$184
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:26 pm
DSM
- SNA
1 stop5h 39m
American Airlines
Deal found 2/1![American Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:30 am
DSM
- SNA
2 stops8h 50m
United Airlines
Deal found 2/1![United Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:15 pm
DSM
- SNA
1 stop5h 05m
Southwest
Deal found 2/2![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:05 pm
DSM
- SNA
3 stops40h 08m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:32 pm
DSM
- SNA
2 stops18h 19m
Frontier
Deal found 2/1![Frontier logo]()
$231
Find flight deals from Des Moines to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $150 (Mytrip) |
One-way from | $91 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $332 |
Good round-trip deal | $137 or less |
Good one-way deal | $150 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Des Moines to Santa Ana that are best for you.
Fly from
Des Moines
Fly to
Santa Ana
Route
Depart
Return
Price
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Fri 3/20
8:22 pm-9:53 am
1 stop15h 31m
Santa Ana J. Wayne/Orange Cnty
Fri 3/27
3:21 pm-7:16 pm
2 stops25h 55m
$259
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Fri 2/20
7:15 am-9:15 am
Nonstop4h 00m
Santa Ana J. Wayne/Orange Cnty
Mon 2/23
10:05 am-3:24 pm
Nonstop3h 19m
$276
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Fri 4/24
9:45 am-11:36 am
Nonstop3h 51m
Santa Ana J. Wayne/Orange Cnty
Sun 4/26
8:20 pm-1:29 pm
2 stops15h 09m
$293
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Sat 3/28
10:00 am-8:50 am
1 stop24h 50m
Santa Ana J. Wayne/Orange Cnty
Mon 3/30
9:45 am-3:02 pm
Nonstop3h 17m
$347
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Thu 2/26
7:27 pm-10:46 am
1 stop17h 19m
Santa Ana J. Wayne/Orange Cnty
Mon 3/9
9:45 am-3:01 pm
Nonstop3h 16m
$348
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Fri 2/20
7:17 pm-3:42 pm
2 stops22h 25m
Santa Ana J. Wayne/Orange Cnty
Mon 2/23
10:05 am-3:24 pm
Nonstop3h 19m
$353
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Thu 2/19
7:32 pm-10:46 am
1 stop17h 14m
Santa Ana J. Wayne/Orange Cnty
Mon 2/23
10:05 am-3:24 pm
Nonstop3h 19m
$371
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Wed 4/22
6:55 am-1:30 pm
2 stops8h 35m
Santa Ana J. Wayne/Orange Cnty
Sat 4/25
8:00 am-6:00 pm
2 stops8h 00m
$374
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Wed 4/22
6:30 pm-9:50 pm
1 stop5h 20m
Santa Ana J. Wayne/Orange Cnty
Fri 4/24
8:50 am-3:30 pm
1 stop4h 40m
$384
Des MoinesSanta Ana
DSM - SNA
DSMSNA
Des Moines
Fri 3/20
7:00 am-8:55 am
Nonstop3h 55m
Santa Ana J. Wayne/Orange Cnty
Mon 3/23
11:32 am-7:16 pm
1 stop5h 44m
$388
Showing 1-10 of 22 results
Compare providers for flights from Des Moines to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santa Ana in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Des Moines with our price prediction graph.
DSM-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Santa Ana
How far ahead should I book a flight from Des Moines to Santa Ana, California?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Santa Ana. Price data was last updated on January 30, 2026.
To ensure you get the cheapest price possible for a flight from Des Moines to Santa Ana, California, you should look to book at least 30 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Des Moines to Santa Ana, California?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Santa Ana, California (average of $101). Flying from Des Moines to Santa Ana, California in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated February 4, 2026.
Read through reviews of airlines operating flights from Des Moines to Santa Ana, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
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Find useful and relevant information for your journey from Des Moines to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Santa Ana flights
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Top 5 airlines flying from Des Moines to Santa Ana
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$106 | Average$181 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$130 | Average$273 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$433 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$286 | Average$405 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$340 | Average$483 | FlexibilityNo cancel fee | On-time63% |