How long is the flight from Florence, South Carolina to San Francisco?

A quick flight from Florence, South Carolina to San Francisco can take about 7h 37m. American Airlines provides one of the quickest options available for as low as $601. Florence, South Carolina and San Francisco are separated by a distance of 2377 mi.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What is the cheapest time of day to fly from FLO to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florence, South Carolina to San Francisco as you normally would.

Most accurate provider : When it comes to deals on Florence, South Carolina-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Florence, South Carolina-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Florence, South Carolina-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Florence to San Francisco that include hotel bookings?

Yes. In addition to deals on Florence to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florence to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to San Francisco.

Can I find deals for business class flights from Florence to San Francisco?

Yes. Cheapflights offers flight deals from Florence to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$601+ Flights from Florence, SC to San Francisco

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Cheap flight deals from Florence to San Francisco

Best flights from Florence to San Francisco
Discover carefully curated flight deals from Florence to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 22, 2025.

Mon 1/56:30 pmFLO - SFO

1 stop7h 37mAmerican Airlines

Fri 1/97:00 amSFO - FLO

1 stop7h 09mAmerican Airlines

Deal found 12/21

$601

Sun 1/41:07 pmFLO - SFO

1 stop10h 44mAmerican Airlines

Thu 1/87:00 amSFO - FLO

1 stop7h 09mAmerican Airlines

Deal found 12/20

$601

Last-minute flights from Florence to San Francisco
Discover last-minute flight deals from Florence to San Francisco. Data last updated December 22, 2025 and is based on user searches.

Sun 1/41:07 pmFLO - SFO

1 stop10h 44mAmerican Airlines

Thu 1/87:00 amSFO - FLO

1 stop7h 09mAmerican Airlines

Deal found 12/20

$601

Find flight deals from Florence to San Francisco

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$601 (American Airlines)

Provider with most accurate pricing for Florence-San Francisco flight deals.

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Provider most trusted by Cheapflights users for Florence-San Francisco flights.

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From Florence to San Francisco

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Mon 1/5

6:30 pm-11:07 pm

1 stop7h 37m

San Francisco

Fri 1/9

7:00 am-5:09 pm

1 stop7h 09m

$601

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Sun 1/4

1:07 pm-8:51 pm

1 stop10h 44m

San Francisco

Thu 1/8

7:00 am-5:09 pm

1 stop7h 09m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Compare providers for flights from Florence to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to San Francisco in December.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Florence, South Carolina-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Florence, South Carolina-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Florence, South Carolina-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Florence with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to San Francisco

What is the cheapest month to book a flight from Florence, South Carolina to San Francisco?

Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to San Francisco (average of $106). Flying from Florence, South Carolina to San Francisco in June is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with American Airlines from Florence to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,052 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

American Airlines

7.2

Good

11,052 reviews

American Airlines

7.2

Good

11,052 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

How long is the flight from Florence, South Carolina to San Francisco?
A quick flight from Florence, South Carolina to San Francisco can take about 7h 37m. American Airlines provides one of the quickest options available for as low as $601. Florence, South Carolina and San Francisco are separated by a distance of 2377 mi.
Can I find deals for flights from Florence to San Francisco that include hotel bookings?
Yes. In addition to deals on Florence to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florence to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to San Francisco.
Can I find deals for business class flights from Florence to San Francisco?
Yes. Cheapflights offers flight deals from Florence to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florence, South Carolina to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to San Francisco (average of $106). Flying from Florence, South Carolina to San Francisco in June is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

South San Francisco

Santa Cruz

Livermore

Turlock

Manteca

Watsonville

Redwood City

Sunnyvale

Santa Clara

San Bruno

Daly City

San Carlos

Vallejo

Hollister

San Ramon

Foster City

Union City

Davis

Emeryville

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Florence to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$326	Average$416	FlexibilityNo cancel fee	On-time71%

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$601+ Cheap flights from Florence, SC to San Francisco (FLO - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to San Francisco

Best flights from Florence to San FranciscoDiscover carefully curated flight deals from Florence to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 22, 2025.

Discover carefully curated flight deals from Florence to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 22, 2025.

Find flight deals from Florence to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to San Francisco that are best for you.

Compare providers for flights from Florence to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to San Francisco in December.

Best time to book a flight from Florence to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Florence with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florence to San Francisco

What is the cheapest month to book a flight from Florence, South Carolina to San Francisco?

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with American Airlines from Florence to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florence to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Florence, South Carolina to San Francisco?

Can I find deals for flights from Florence to San Francisco that include hotel bookings?

How can I find direct flights from Florence to San Francisco?

Can I find deals for business class flights from Florence to San Francisco?

What is the cheapest month to book a flight from Florence, South Carolina to San Francisco?

Traveling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Florence to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Florence to San Francisco

100% Free

Book with Flexibility

Travel Smart

Best flights from Florence to San Francisco
Discover carefully curated flight deals from Florence to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 22, 2025.