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$94+ Cheap flights from St. Louis to San Diego (STL - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAN
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to San Diego are usually found in January or August, booked 78 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from St. Louis to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$240
(Mytrip)

One-way from

$94
(Mytrip)

Popular in

March

Cheapest in

January

Average price

$414

Good round-trip deal

$495 or less
From Lambert-St Louis to San Diego
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One-way flight from Lambert-St Louis to San Diego
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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Lambert-St Louis to San Diego.
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Find flight deals from St. Louis to San Diego

Cheapest flights from St. Louis to San Diego
Explore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1010:47 amSTL - SAN
2 stops25h 08mSpirit Airlines
Thu 7/176:15 amSAN - STL
2 stops25h 37mSpirit Airlines
Deal found 6/12$240
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:54 pmSTL - SAN
1 stop5h 58mFrontier
Mon 8/259:11 pmSAN - STL
1 stop10h 00mFrontier
Deal found 6/9$251
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/227:23 amSTL - SAN
1 stop8h 37mAmerican Airlines
Wed 7/3010:45 pmSAN - STL
1 stop7h 11mAmerican Airlines
Deal found 6/10$319
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/111:10 pmSTL - SAN
Nonstop3h 45mSouthwest
Mon 9/154:15 pmSAN - STL
1 stop5h 10mSouthwest
Deal found 6/11$327
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/89:20 amSTL - SAN
3 stops39h 46mMultiple Airlines
Tue 7/157:00 pmSAN - STL
2 stops13h 29mMultiple Airlines
Deal found 6/9$332
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:00 amSTL - SAN
1 stop6h 34mUnited Airlines
Wed 8/138:00 amSAN - STL
1 stop6h 45mUnited Airlines
Deal found 6/11$337
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/302:23 pmSTL - SAN
1 stop6h 16mDelta
Tue 8/56:25 amSAN - STL
1 stop8h 17mDelta
Deal found 6/10$349
This Alaska Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/283:35 pmSTL - SAN
1 stop9h 18mAlaska Airlines
Wed 10/110:18 pmSAN - STL
2 stops17h 16mAlaska Airlines
Deal found 6/10$376

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.

Fly from

St. Louis

Fly to

San Diego

Route

Depart

Return

Price

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Thu 7/10

10:47 am-9:55 am

2 stops25h 08m

San Diego

Thu 7/17

6:15 am-9:52 am

2 stops25h 37m

$240

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Fri 8/22

7:54 pm-11:52 pm

1 stop5h 58m

San Diego

Mon 8/25

9:11 pm-9:11 am

1 stop10h 00m

$251

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Tue 7/22

7:23 am-2:00 pm

1 stop8h 37m

San Diego

Wed 7/30

10:45 pm-7:56 am

1 stop7h 11m

$319

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Tue 7/8

9:20 am-11:06 pm

3 stops39h 46m

San Diego

Tue 7/15

7:00 pm-10:29 am

2 stops13h 29m

$332

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Thu 8/7

5:00 am-9:34 am

1 stop6h 34m

San Diego

Wed 8/13

8:00 am-4:45 pm

1 stop6h 45m

$337

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Wed 7/30

2:23 pm-6:39 pm

1 stop6h 16m

San Diego

Tue 8/5

6:25 am-4:42 pm

1 stop8h 17m

$349

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Tue 7/22

5:45 pm-9:50 pm

1 stop6h 05m

San Diego

Wed 7/30

8:50 am-6:25 pm

2 stops7h 35m

$354

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Tue 8/12

3:24 pm-11:42 pm

2 stops10h 18m

San Diego

Sat 8/16

8:45 pm-2:26 pm

1 stop15h 41m

$439

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Mon 7/7

7:13 pm-6:26 pm

2 stops25h 13m

$94

St. LouisSan Diego

STL - SAN

STLSAN

Lambert-St Louis

Fri 6/27

2:27 pm-6:16 pm

1 stop5h 49m

$135

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 16 results
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Best time to book a flight from St. Louis to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to San Diego

How far ahead should I book a flight from St. Louis to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to San Diego. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from St. Louis to San Diego, you should look to book at least 78 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from St. Louis to San Diego?

Currently, August is the cheapest month in which you can book a flight from St. Louis to San Diego (average of $286). Flying from St. Louis to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SAN?

Find hourly flight availability from St. Louis to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 5% on flights from St. Louis to San Diego by exploring options for tickets in the evening.

What is the cheapest day to fly from St. Louis to San Diego?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to San Diego. Price data was last updated on June 8, 2025.

Travelers seeking maximum savings on their St. Louis to San Diego flight should consider departing on Sunday at noon when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from St. Louis to San Diego to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Food

7.1

Overall

8.0

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from St. Louis to San Diego?

    If you book a flight from St. Louis to San Diego, you will be flying from Lambert-St Louis to San Diego. Flights to San Diego (SAN) from Lambert-St Louis (STL) take 3h 45m for a nonstop flight. There is 1 flight from Lambert-St Louis to San Diego per day from 5 airlines.

  • What are the cheapest airlines flying from St. Louis to San Diego round-trip?

    Flying on Spirit Airlines is currently your cheapest option to San Diego, with prices starting at $240. Additional round-trip tickets that might be worth considering are offered by Frontier and American Airlines, with the lowest prices starting at $251 and $319, respectively. You may be able to fly from St. Louis to San Diego for 31% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from St. Louis to San Diego one-way?

    The cheapest airlines for a one-way flight from St. Louis to San Diego are Spirit Airlines ($94), Frontier ($135), and Southwest ($159).

  • What are the cheapest flights from St. Louis to San Diego?

    Looking for the cheapest flight from St. Louis to San Diego? While on average our users pay $585, our data indicates the cheapest price to be $379. The most popular route (Lambert-St Louis - San Diego), is priced around $250.

  • Where are the most common layover locations when flying from St. Louis to San Diego?

    St. Louis to San Diego flights have a layover in Denver most often.

  • What are some popular things to do or see while on a layover in Denver?

    The majority of Denver visitors spend their time at Coors Field, Paramount Theatre, and Larimer Square. Travelers on a layover in Denver can visit Coors Field, Paramount Theatre, and Larimer Square, by traveling 18.4 mi, 18.6 mi, and 18.9 mi, respectively after landing at Denver Intl. Travelers can rent a car at Denver Intl for an average daily rate of $54 to make sightseeing during their layover a little easier.

  • Where are the least popular layover locations for St. Louis to San Diego flights?

    St. Louis to San Diego flights have a layover in Phoenix the least frequently.

  • Can I find deals for flights from St. Louis to San Diego that include hotel bookings?

    Yes. In addition to deals on St. Louis to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to San Diego.

  • Can I find deals for business class flights from St. Louis to San Diego?

    Yes. Cheapflights offers flight deals from St. Louis to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to San Diego?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to San Diego (average of $286). Flying from St. Louis to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Imperial Beach
La Mesa
Alpine
Lemon Grove
Poway
Santee
Coronado

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Alternative routes for St. Louis to San Diego

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Top 5 airlines flying from St. Louis to San Diego

Discover the top 5 airlines that operate flights from St. Louis to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$110Average$195FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$220Average$314FlexibilityNo cancel feeOn-time71%
DeltaCheapest$246Average$289FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$247Average$358FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$322Average$490FlexibilityNo cancel feeOn-time63%

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