$61+ Cheap flights from St. Louis to San Diego (STL - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAN
Oct 11 — Oct 181
1 adult, Economy
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Find cheap flights from St. Louis to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to San Diego are usually found in January or February, booked 78 days in advance, depart on a Wednesday or Tuesday and return on a Thursday
Cheap flight deals from St. Louis to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.
Round-trip from | $128 (Kiwi.com) |
|---|---|
One-way from | $61 (Trip.com) |
Popular in | March |
Cheapest in | January |
Average price | $339 |
Good round-trip deal | $385 or less |
Good one-way deal | $174 or less |
Find flight deals from St. Louis to San Diego
Cheapest flights from St. Louis to San DiegoExplore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.
Explore the most affordable flight options available from St. Louis to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:55 pmSTL - SAN
1 stop28h 29mFrontier
Mon 10/610:20 amSAN - STL
1 stop20h 47mFrontier
Deal found 9/10![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:38 pmSTL - SAN
1 stop12h 26mFrontier
Tue 11/46:41 amSAN - STL
1 stop24h 26mFrontier
Deal found 9/10![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/27:45 pmSTL - SAN
1 stop17h 32mFrontier
Thu 11/63:59 pmSAN - STL
1 stop19h 58mFrontier
Deal found 9/10![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:45 pmSTL - SAN
1 stop17h 32mFrontier
Mon 11/175:47 pmSAN - STL
1 stop13h 20mFrontier
Deal found 9/9![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:52 pmSTL - SAN
1 stop5h 58mFrontier
Tue 10/216:41 amSAN - STL
1 stop24h 26mFrontier
Deal found 9/10![Frontier logo]()
$143
This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:51 pmSTL - SAN
1 stop6h 00mFrontier
Mon 10/139:03 pmSAN - STL
1 stop10h 04mFrontier
Deal found 9/10![Frontier logo]()
$144
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/229:29 pmSTL - SAN
1 stop25h 55mFrontier
Wed 9/247:15 amSAN - STL
1 stop23h 51mFrontier
Deal found 9/10![Frontier logo]()
$145
This Booking.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/199:35 pmSTL - SAN
1 stop22h 55mFrontier
Mon 9/226:35 amSAN - STL
1 stop24h 31mFrontier
Deal found 9/8![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:55 pmSTL - SAN
1 stop5h 58mFrontier
Sun 10/59:03 pmSAN - STL
1 stop10h 03mFrontier
Deal found 9/9![Frontier logo]()
$149
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:52 pmSTL - SAN
1 stop5h 58mFrontier
Sun 10/267:23 pmSAN - STL
1 stop12h 09mFrontier
Deal found 9/10![Frontier logo]()
$154
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from St. Louis to San Diego that are best for you.
Fly from
St. Louis
Fly to
San Diego
Route
Depart
Return
Price
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 10/24
7:52 pm-11:50 pm
1 stop5h 58m
San Diego
Sun 10/26
7:23 pm-9:32 am
1 stop12h 09m
$154
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Thu 10/9
7:52 pm-8:08 pm
1 stop26h 16m
San Diego
Sun 10/12
6:41 am-9:07 am
1 stop24h 26m
$203
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Thu 10/9
7:52 pm-8:08 pm
1 stop26h 16m
San Diego
Sat 10/11
8:00 am-3:56 pm
1 stop5h 56m
$205
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sat 11/1
8:40 pm-12:17 pm
1 stop17h 37m
San Diego
Tue 11/4
8:00 am-9:07 am
2 stops23h 07m
$210
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Fri 10/10
10:59 pm-8:51 pm
2 stops23h 52m
San Diego
Mon 10/13
9:03 pm-9:07 am
1 stop10h 04m
$211
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Thu 9/18
10:49 am-5:42 pm
1 stop8h 53m
San Diego
Sun 9/21
9:03 pm-9:06 am
1 stop10h 03m
$226
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Tue 10/7
4:55 pm-6:50 pm
Nonstop3h 55m
San Diego
Tue 10/14
2:40 pm-11:10 pm
1 stop6h 30m
$241
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Sat 11/1
1:45 pm-7:55 pm
2 stops8h 10m
San Diego
Tue 11/4
8:40 am-5:15 pm
2 stops6h 35m
$253
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Mon 9/15
2:38 pm-11:17 pm
1 stop10h 39m
San Diego
Thu 9/18
9:03 pm-9:06 am
1 stop10h 03m
$258
St. LouisSan Diego
STL - SAN
STLSAN
Lambert-St Louis
Mon 10/27
9:45 am-11:40 am
Nonstop3h 55m
San Diego
Tue 11/4
12:40 pm-9:00 pm
1 stop6h 20m
$271
Showing 1-10 of 20 results
Best time to book a flight from St. Louis to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to San Diego
Prices
More
How far ahead should I book a flight from St. Louis to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from St. Louis to San Diego. Price data was last updated on August 29, 2025.
To ensure you get the cheapest price possible for a flight from St. Louis to San Diego, you should look to book at least 78 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to San Diego?
Currently, August is the cheapest month in which you can book a flight from St. Louis to San Diego (average of $286). Flying from St. Louis to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to SAN?
Find hourly flight availability from St. Louis to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.
Unlike in the morning, when flights are generally more expensive, you can save up to 17% on flights from St. Louis to San Diego by exploring options for tickets in the afternoon.
What is the cheapest day to fly from St. Louis to San Diego?
Use this chart to determine the cheapest time to fly round-trip from St. Louis to San Diego. Price data was last updated on September 7, 2025.
Travelers seeking maximum savings on their St. Louis to San Diego flight should consider departing on Sunday at noon when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
What’s the top layover airport for flights from St. Louis to San Diego?
Share of 1-stop round-trip flights from St. Louis to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Denver (DEN) – chosen by Cheapflights users on 67% of 1-stop itineraries from St. Louis to San Diego on Cheapflights.
What’s the fastest layover option from St. Louis to San Diego?
Shortest average travel time for 1-stop one-way flights from St. Louis to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 6h 44m.
What’s the fastest layover option from St. Louis to San Diego?
Shortest average travel time for 1-stop one-way flights from St. Louis to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 6h 44m.
Which airport typically offers the quickest layover for flights from St. Louis to San Diego?
Average layover duration for 1-stop one-way flights from St. Louis to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Houston (IAH) offer the fastest connection on this route, with an average layover time of 1h 03m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from St. Louis to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from St. Louis to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City
Alpine
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for St. Louis to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from St. Louis to San Diego
Discover the top 5 airlines that operate flights from St. Louis to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$208 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$234 | Average$305 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$307 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$266 | Average$365 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$313 | Average$494 | FlexibilityNo cancel fee | On-time63% |