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$445+ Cheap flights from Columbia, MO to San Diego (COU - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SAN
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Columbia to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$445
(United Airlines)
From Columbia Regional to San Diego
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Find flight deals from Columbia to San Diego

Cheapest flights from Columbia to San Diego
Explore the most affordable flight options available from Columbia to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/139:00 amCOU - SAN
1 stop10h 34mUnited Airlines
Tue 12/168:45 amSAN - COU
1 stop10h 06mUnited Airlines
Deal found 9/14$445
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1312:09 pmCOU - SAN
2 stops8h 16mAmerican Airlines
Tue 12/1610:09 amSAN - COU
2 stops9h 51mAmerican Airlines
Deal found 9/13$461
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1011:37 amCOU - SAN
1 stop9h 52mAmerican Airlines
Mon 10/136:16 amSAN - COU
1 stop13h 15mAmerican Airlines
Deal found 9/14$472
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1011:37 amCOU - SAN
1 stop9h 52mAmerican Airlines
Fri 10/176:16 amSAN - COU
1 stop13h 15mAmerican Airlines
Deal found 9/16$475
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:00 amCOU - SAN
1 stop13h 54mUnited Airlines
Sun 11/210:30 pmSAN - COU
1 stop20h 49mUnited Airlines
Deal found 9/14$480
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:23 pmCOU - SAN
1 stop5h 57mAmerican Airlines
Sun 10/56:15 amSAN - COU
1 stop7h 38mAmerican Airlines
Deal found 9/16$535
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:01 amCOU - SAN
2 stops16h 40mUnited Airlines
Mon 10/1310:30 pmSAN - COU
1 stop20h 57mUnited Airlines
Deal found 9/16$560
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/299:01 amCOU - SAN
1 stop26h 11mUnited Airlines
Fri 10/37:28 pmSAN - COU
2 stops16h 49mUnited Airlines
Deal found 9/14$590

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Columbia to San Diego that are best for you.

Fly from

Columbia

Fly to

San Diego

Route

Depart

Return

Price

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 12/13

9:00 am-5:34 pm

1 stop10h 34m

San Diego

Tue 12/16

4:11 pm-8:51 pm

1 stop26h 40m

$445

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 12/13

12:09 pm-6:25 pm

2 stops8h 16m

San Diego

Tue 12/16

10:09 am-10:00 pm

2 stops9h 51m

$461

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 10/10

11:37 am-7:29 pm

1 stop9h 52m

San Diego

Mon 10/13

6:16 am-9:31 pm

1 stop13h 15m

$472

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Columbia to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Diego

What is the cheapest time of day to fly from COU to SAN?

Find hourly flight availability from Columbia to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Columbia, Missouri to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 9% versus a flight in the morning.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 16, 2025.
See what other customers who have flown with American Airlines from Columbia to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Diego?

    A quick flight from Columbia, Missouri to San Diego can take about 10h 34m. United Airlines provides one of the quickest options available for as low as $445. Columbia, Missouri and San Diego are separated by a distance of 1456 mi.

  • What is the cheapest airline to fly from Columbia, Missouri to San Diego round-trip?

    Our cheapest airline available from Columbia, Missouri to San Diego is American Airlines. Our recent data shows that you can find tickets from as low as $429 on this airline.

  • Can I find deals for flights from Columbia to San Diego that include hotel bookings?

    Yes. In addition to deals on Columbia to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Diego.

  • Can I find deals for business class flights from Columbia to San Diego?

    Yes. Cheapflights offers flight deals from Columbia to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Columbia, Missouri to San Diego (average of $286). Flying from Columbia, Missouri to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City

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Top airline flying from Columbia to San Diego

Discover the top airline that operate flights from Columbia to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$429Average$568FlexibilityNo cancel feeOn-time71%

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