HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$318+ Cheap flights from Columbia, MO to San Diego (COU - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SAN
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbia to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbia to San Diego

Cheapest flights from Columbia to San Diego
Explore the most affordable flight options available from Columbia to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:30 am
COU
-
SAN
1 stop9h 56m
American Airlines
Sat 6/610:45 pm
SAN
-
COU
1 stop9h 21m
American Airlines
Deal found 4/29$318
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:47 pm
COU
-
SAN
1 stop7h 01m
American Airlines
Mon 6/1510:45 pm
SAN
-
COU
1 stop9h 21m
American Airlines
Deal found 4/28$338
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:00 am
COU
-
SAN
1 stop7h 11m
United Airlines
Sat 10/3111:00 am
SAN
-
COU
2 stops8h 20m
United Airlines
Deal found 4/26$344
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:17 pm
COU
-
SAN
1 stop7h 16m
American Airlines
Sat 10/3111:58 am
SAN
-
COU
1 stop8h 37m
American Airlines
Deal found 4/26$363
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:28 pm
COU
-
SAN
1 stop9h 05m
American Airlines
Sun 5/1710:40 pm
SAN
-
COU
1 stop8h 51m
American Airlines
Deal found 4/28$388
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:32 pm
COU
-
SAN
1 stop6h 54m
American Airlines
Sat 7/2510:45 pm
SAN
-
COU
1 stop9h 16m
American Airlines
Deal found 4/26$397
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:30 am
COU
-
SAN
1 stop9h 00m
United Airlines
Sat 8/2911:00 am
SAN
-
COU
1 stop7h 30m
United Airlines
Deal found 4/29$408

Find flight deals from Columbia to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$318
(American Airlines)

Popular in

December

Cheapest in

February

Average price

$568
Provider with most accurate pricing for Columbia Regional-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-San Diego flights.
Search Deals
From Columbia Regional to San Diego
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Columbia to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 5/28

10:30 am-6:26 pm

1 stop9h 56m

San Diego

Sat 6/6

10:45 pm-10:06 am

1 stop9h 21m

$318
Quickest round-trip

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Wed 8/26

11:30 am-6:30 pm

1 stop9h 00m

San Diego

Sat 8/29

11:00 am-8:30 pm

1 stop7h 30m

$408

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 9/17

11:30 am-7:55 pm

2 stops10h 25m

San Diego

Mon 9/21

7:41 pm-10:55 am

2 stops13h 14m

$439

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Mon 7/20

3:05 pm-11:54 pm

2 stops10h 49m

San Diego

Mon 7/27

8:32 pm-10:48 am

2 stops12h 16m

$529

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Tue 8/11

3:05 pm-10:10 pm

1 stop9h 05m

San Diego

Fri 8/14

6:55 pm-8:30 pm

1 stop23h 35m

$546
Cheapest one-way
Quickest one-way

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 5/21

9:14 am-7:51 pm

2 stops12h 37m

$529

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Sorted by cheapest first

Compare providers for flights from Columbia to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to San Diego in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Diego

How much does it cost to fly round-trip from Columbia, Missouri to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 30, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,678 reviews

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Crew

8.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,678 reviews
United Airlines
7.4
Good
9,678 reviews

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Crew

8.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,686 reviews
United Airlines
7.4
Good
9,678 reviews

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Crew

8.1

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Diego?

    A quick flight from Columbia, Missouri to San Diego can take about 9h. American Airlines provides one of the quickest options available for as low as $408. Columbia, Missouri and San Diego are separated by a distance of 1456 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Columbia, Missouri to San Diego round-trip?

    Our cheapest airline available from Columbia, Missouri to San Diego is United Airlines. Our recent data shows that you can find tickets from as low as $258 on this airline. An additional option worth looking into is American Airlines, starting at $429. United Airlines is currently priced 48% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbia to San Diego that include hotel bookings?

    Yes. In addition to deals on Columbia to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Diego.

  • Can I find deals for business class flights from Columbia to San Diego?

    Yes. Cheapflights offers flight deals from Columbia to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbia to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Kansas City to Las Vegas flights
St. Louis to Las Vegas flights
Kansas City to Los Angeles flights
St. Louis to San Francisco flights
St. Louis to Los Angeles flights
Kansas City to San Francisco flights
St. Louis to San Diego flights
Kansas City to San Diego flights
Kansas City to Ontario flights
Kansas City to Sacramento flights
Kansas City to Santa Ana flights
St. Louis to Ontario flights
St. Louis to Reno flights
St. Louis to San Jose flights
Kansas City to San Jose flights
Kansas City to Oakland flights
Kansas City to Long Beach flights
St. Louis to Sacramento flights
St. Louis to Oakland flights
Kansas City to Reno flights
Springfield to Las Vegas flights
Springfield to Los Angeles flights
St. Louis to Santa Ana flights
St. Louis to Fresno flights
Kansas City to Fresno flights
Kansas City to Santa Barbara flights
Springfield to San Jose flights
St. Louis to Burbank flights
Kansas City to Burbank flights
Springfield to Sacramento flights
Kansas City to Palm Springs flights
Springfield to Ontario flights
Springfield to San Francisco flights
Springfield to Reno flights
Springfield to San Diego flights
Columbia to Las Vegas flights
St. Louis to Palm Springs flights
St. Louis to San Luis Obispo flights
Springfield to Burbank flights
St. Louis to Medford flights
St. Louis to Long Beach flights
Kansas City to San Luis Obispo flights
Springfield to Santa Ana flights
St. Louis to Monterey flights
Kansas City to Monterey flights
Springfield to Monterey flights
Columbia to San Francisco flights
Kansas City to Medford flights
Joplin to Las Vegas flights
St. Louis to Redding flights

Top 2 airlines flying from Columbia to San Diego

Discover the top 2 airlines that operate flights from Columbia to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$258Average$343FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$429Average$536FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2026 Cheapflights