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$318+ Cheap flights from Columbia, MO to San Diego (COU - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
COU — SAN
Jun 10 — Jun 171
Wed 6/10
Wed 6/17
1 adult, Economy
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Cheap flight deals from Columbia to San Diego

Cheapest flights from Columbia to San Diego
Explore the most affordable flight options available from Columbia to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.

This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:00 am
COU
-
SAN
1 stop7h 11m
United Airlines
Mon 10/52:09 pm
SAN
-
COU
1 stop8h 24m
United Airlines
Deal found 5/6$318
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:26 pm
COU
-
SAN
1 stop6h 33m
American Airlines
Tue 7/2110:45 pm
SAN
-
COU
1 stop9h 16m
American Airlines
Deal found 5/9$328
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:25 pm
COU
-
SAN
2 stops11h 06m
United Airlines
Sat 8/2210:40 pm
SAN
-
COU
1 stop8h 55m
United Airlines
Deal found 5/10$334
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:19 pm
COU
-
SAN
1 stop8h 40m
American Airlines
Wed 5/277:28 am
SAN
-
COU
1 stop8h 34m
American Airlines
Deal found 5/6$353
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:19 pm
COU
-
SAN
1 stop7h 18m
American Airlines
Thu 7/1610:45 pm
SAN
-
COU
1 stop9h 16m
American Airlines
Deal found 5/10$358
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:00 am
COU
-
SAN
1 stop7h 50m
United Airlines
Sat 9/198:45 am
SAN
-
COU
2 stops11h 04m
United Airlines
Deal found 5/6$370
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:16 am
COU
-
SAN
2 stops9h 10m
United Airlines
Sat 8/2210:40 pm
SAN
-
COU
1 stop8h 55m
United Airlines
Deal found 5/10$373
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:25 pm
COU
-
SAN
1 stop9h 09m
United Airlines
Thu 7/1610:49 am
SAN
-
COU
2 stops10h 44m
United Airlines
Deal found 5/8$389

Find flight deals from Columbia to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$318
(American Airlines)

One-way from

$318
(American Airlines)

Popular in

August

Cheapest in

February

Average price

$353
Provider with most accurate pricing for Columbia Regional-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-San Diego flights.
Search Deals
From Columbia Regional to San Diego
Search Deals
One-way flight from Columbia Regional to San Diego
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Columbia to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 10/1

5:00 am-10:11 am

1 stop7h 11m

San Diego

Mon 10/5

2:09 pm-12:33 am

1 stop8h 24m

$318

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 7/16

6:32 pm-11:26 pm

1 stop6h 54m

San Diego

Mon 7/20

10:45 pm-10:01 am

1 stop9h 16m

$328

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 5/23

5:19 pm-11:59 pm

1 stop8h 40m

San Diego

Wed 5/27

9:50 am-10:25 pm

2 stops10h 35m

$359

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 7/11

3:25 pm-10:34 pm

1 stop9h 09m

San Diego

Thu 7/16

10:49 am-11:33 pm

2 stops10h 44m

$389

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 8/22

3:05 pm-10:10 pm

1 stop9h 05m

San Diego

Wed 8/26

8:45 am-9:49 pm

2 stops11h 04m

$414

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Tue 8/25

8:00 am-3:02 pm

1 stop9h 02m

San Diego

Sat 8/29

10:40 pm-9:35 am

1 stop8h 55m

$418

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 9/17

11:30 am-7:55 pm

2 stops10h 25m

San Diego

Mon 9/21

7:41 pm-10:55 am

2 stops13h 14m

$419

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 8/21

8:00 am-5:26 pm

2 stops11h 26m

San Diego

Mon 8/24

10:40 pm-10:08 am

1 stop9h 28m

$424
Cheapest one-way
Quickest one-way

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sun 6/21

6:47 pm-11:48 pm

1 stop7h 01m

$318

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sun 6/21

9:14 am-10:08 am

2 stops26h 54m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/7

Sorted by cheapest first

Compare providers for flights from Columbia to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to San Diego in May.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbia, Missouri-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbia, Missouri-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbia to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to San Diego

How much does it cost to fly round-trip from Columbia, Missouri to San Diego?

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 11, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,699 reviews

Comfort

7.3

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,699 reviews
United Airlines
7.4
Good
9,699 reviews

Comfort

7.3

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,667 reviews
United Airlines
7.4
Good
9,699 reviews

Comfort

7.3

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Columbia to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbia, Missouri to San Diego?

    A quick flight from Columbia, Missouri to San Diego can take about 6h 54m. United Airlines provides one of the quickest options available for as low as $328. Columbia, Missouri and San Diego are separated by a distance of 1456 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Columbia, Missouri to San Diego round-trip?

    Our cheapest airline available from Columbia, Missouri to San Diego is United Airlines. Our recent data shows that you can find tickets from as low as $258 on this airline. An additional option worth looking into is American Airlines, starting at $429. United Airlines is currently priced 48% below the average price you’ll pay for this route.

  • Can I find deals for flights from Columbia to San Diego that include hotel bookings?

    Yes. In addition to deals on Columbia to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to San Diego.

  • Can I find deals for business class flights from Columbia to San Diego?

    Yes. Cheapflights offers flight deals from Columbia to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
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National City
Coronado
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Poway
Julian
Lemon Grove

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Top 2 airlines flying from Columbia to San Diego

Discover the top 2 airlines that operate flights from Columbia to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$258Average$378FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$429Average$536FlexibilityNo cancel feeOn-time71%

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