$309+ Cheap flights from Des Moines to Pittsburgh (DSM - PIT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PIT
Dec 5 — Dec 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Pittsburgh with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Pittsburgh
Cheapest
Best
Last-minute
Cheapest flights from Des Moines to PittsburghExplore the most affordable flight options available from Des Moines to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Des Moines to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop4h 17m
Tue 12/18:00 am -
1 stop7h 13m
Deal found 11/3![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:58 pm -
1 stop6h 02m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 11/1![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:11 am -
2 stops9h 43m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 11/1![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:10 am -
2 stops6h 30m
Fri 12/257:25 pm -
1 stop3h 40m
Deal found 11/2![Southwest logo]()
$351
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:10 am -
2 stops6h 30m
Wed 1/66:50 am -
2 stops8h 20m
Deal found 11/1![Southwest logo]()
$356
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:30 pm -
1 stop4h 15m
Mon 12/75:35 am -
2 stops6h 50m
Deal found 11/2![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:11 am -
1 stop7h 07m
Sat 12/510:01 am -
1 stop4h 34m
Deal found 11/1![American Airlines logo]()
$373
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
2 stops8h 22m
Mon 12/287:28 pm -
1 stop4h 49m
Deal found 11/1![United Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
1 stop3h 40m
Fri 12/114:55 pm -
2 stops7h 10m
Deal found 11/4![Southwest logo]()
$381
Best flights from Des Moines to PittsburghDiscover carefully curated flight deals from Des Moines to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Des Moines to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:48 pm -
1 stop5h 20m
Tue 12/16:00 am -
1 stop5h 53m
Deal found 11/4![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:10 am -
1 stop3h 50m
Wed 1/65:50 pm -
1 stop4h 40m
Deal found 11/1![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:31 am -
2 stops7h 23m
Tue 12/15:30 pm -
1 stop6h 30m
Deal found 11/2![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop4h 17m
Tue 12/18:00 am -
1 stop7h 13m
Deal found 11/3![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:53 pm -
1 stop5h 25m
Fri 12/1112:15 pm -
1 stop5h 34m
Deal found 11/4![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:41 am -
1 stop6h 23m
Sun 2/79:24 am -
1 stop5h 44m
Deal found 11/3![American Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/56:30 am -
2 stops7h 50m
Sun 2/71:25 pm -
2 stops10h 40m
Deal found 11/3![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:11 am -
1 stop7h 07m
Sat 12/510:01 am -
1 stop4h 34m
Deal found 10/31![American Airlines logo]()
$373
Last-minute flights from Des Moines to PittsburghDiscover last-minute flight deals from Des Moines to Pittsburgh. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Pittsburgh. Data last updated November 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:11 am -
2 stops9h 43m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 11/1![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop4h 17m
Tue 12/18:00 am -
1 stop7h 13m
Deal found 11/3![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:00 am -
1 stop5h 05m
Thu 12/35:32 pm -
2 stops8h 01m
Deal found 11/2![American Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:11 am -
1 stop7h 07m
Sat 12/510:01 am -
1 stop4h 34m
Deal found 11/1![American Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:30 pm -
1 stop4h 15m
Mon 12/75:35 am -
2 stops6h 50m
Deal found 11/2![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
1 stop3h 40m
Fri 12/114:55 pm -
2 stops7h 10m
Deal found 11/4![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:10 am -
2 stops6h 30m
Fri 12/257:25 pm -
1 stop3h 40m
Deal found 11/2![Southwest logo]()
$351
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:10 am -
2 stops6h 30m
Wed 1/66:50 am -
2 stops8h 20m
Deal found 11/1![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:00 am -
2 stops8h 22m
Mon 12/287:28 pm -
1 stop4h 49m
Deal found 11/1![United Airlines logo]()
$376
Find flight deals from Des Moines to Pittsburgh
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Pittsburgh (PIT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
Popular in | June |
Cheapest in | January |
Average price | $413 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Des Moines to Pittsburgh that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Thu 11/26
2:48 pm-9:08 pm
1 stop5h 20m
Pittsburgh
Tue 12/1
6:00 am-10:53 am
1 stop5h 53m
$309
Quickest round-trip
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Tue 12/22
5:10 am-10:00 am
1 stop3h 50m
Pittsburgh
Wed 1/6
5:50 pm-9:30 pm
1 stop4h 40m
$309
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Fri 11/27
6:45 am-12:02 pm
1 stop4h 17m
Pittsburgh
Tue 12/1
8:00 am-2:13 pm
1 stop7h 13m
$309
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Mon 12/7
4:53 pm-11:18 pm
1 stop5h 25m
Pittsburgh
Fri 12/11
12:15 pm-4:49 pm
1 stop5h 34m
$309
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Thu 11/26
9:31 am-5:54 pm
2 stops7h 23m
Pittsburgh
Tue 12/1
5:30 pm-11:00 pm
1 stop6h 30m
$344
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Fri 2/5
7:41 am-3:04 pm
1 stop6h 23m
Pittsburgh
Sun 2/7
9:24 am-2:08 pm
1 stop5h 44m
$346
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Fri 2/5
6:30 am-3:20 pm
2 stops7h 50m
Pittsburgh
Sun 2/7
1:25 pm-11:05 pm
2 stops10h 40m
$362
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Sat 11/28
7:11 am-3:18 pm
1 stop7h 07m
Pittsburgh
Sat 12/5
10:01 am-1:35 pm
1 stop4h 34m
$373
Sorted by cheapest first
Compare providers for flights from Des Moines to Pittsburgh
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Pittsburgh in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Pittsburgh flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Pittsburgh flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Pittsburgh flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Pittsburgh flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Pittsburgh flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Pittsburgh
Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Des Moines with our price prediction graph.
DSM-PIT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Pittsburgh
Reviews of airlines servicing Pittsburgh
Get insights into the airlines that provide service to Pittsburgh. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Pittsburgh. Reviews last updated November 5, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Pittsburgh. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Pittsburgh?
Book flights to Pittsburgh if you plan to visit one of these locationsMonroeville
Washington
Chester
Mars
Wexford
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Pittsburgh flight routes
Popular flights
Alternative routes for Des Moines to Pittsburgh
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Pittsburgh by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Pittsburgh by cabin class
Find flights from Des Moines to Pittsburgh, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Pittsburgh flights
Browse other Des Moines and Pittsburgh flight options. Last updated on November 5, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Other flights to Pittsburgh
Explore flights to Pittsburgh departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Des Moines to Pittsburgh
Discover the top 4 airlines that operate flights from Des Moines to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$272 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$515 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$314 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$316 | Average$386 | FlexibilityNo cancel fee | On-time69% |