$134+ Cheap flights from Des Moines to Pittsburgh (DSM - PIT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PIT
Nov 22 — Nov 291
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Pittsburgh with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Pittsburgh
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Cheapest flights from Des Moines to PittsburghExplore the most affordable flight options available from Des Moines to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
Explore the most affordable flight options available from Des Moines to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:53 pm -
1 stop4h 53m
Thu 12/36:00 am -
1 stop5h 49m
Deal found 10/20![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:20 am -
1 stop3h 45m
Mon 12/144:00 pm -
2 stops7h 05m
Deal found 10/21![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:40 am -
1 stop8h 35m
Tue 12/158:25 am -
1 stop4h 00m
Deal found 10/21![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
2 stops10h 50m
Thu 12/31:30 pm -
2 stops9h 35m
Deal found 10/20![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop4h 17m
Tue 12/15:41 pm -
1 stop3h 58m
Deal found 10/21![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:58 pm -
1 stop6h 02m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 10/21![American Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:11 am -
2 stops9h 43m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 10/22![American Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:48 pm -
1 stop5h 20m
Tue 12/15:09 pm -
1 stop6h 29m
Deal found 10/21![Delta logo]()
$342
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
1 stop4h 14m
Wed 12/26:10 am -
2 stops7h 29m
Deal found 10/22![United Airlines logo]()
$347
Best flights from Des Moines to PittsburghDiscover carefully curated flight deals from Des Moines to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
Discover carefully curated flight deals from Des Moines to Pittsburgh that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:55 am -
1 stop4h 22m
Wed 1/202:05 pm -
1 stop3h 45m
Deal found 10/21![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:20 am -
1 stop3h 45m
Mon 12/144:00 pm -
2 stops7h 05m
Deal found 10/21![Southwest logo]()
$272
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:27 am -
1 stop5h 57m
Thu 12/36:00 pm -
1 stop4h 25m
Deal found 10/20![United Airlines logo]()
$368
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:15 pm -
1 stop6h 04m
Tue 1/1912:43 pm -
1 stop4h 14m
Deal found 10/21![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:40 am -
1 stop8h 35m
Tue 12/158:25 am -
1 stop4h 00m
Deal found 10/21![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:29 pm -
1 stop4h 28m
Mon 12/1411:17 am -
1 stop5h 54m
Deal found 10/21![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop4h 17m
Tue 12/16:10 am -
1 stop4h 40m
Deal found 10/23![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:45 pm -
2 stops7h 55m
Wed 11/115:35 am -
2 stops6h 50m
Deal found 10/23![Southwest logo]()
$402
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:48 pm -
1 stop5h 20m
Tue 12/15:09 pm -
1 stop6h 29m
Deal found 10/20![Delta logo]()
$342
Last-minute flights from Des Moines to PittsburghDiscover last-minute flight deals from Des Moines to Pittsburgh. Data last updated October 23, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Pittsburgh. Data last updated October 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop6h 13m
Mon 11/95:34 pm -
1 stop6h 05m
Deal found 10/20![American Airlines logo]()
$392
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:50 pm -
2 stops10h 25m
Mon 11/307:40 pm -
1 stop4h 55m
Deal found 10/22![Southwest logo]()
$387
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:11 am -
2 stops9h 43m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 10/22![American Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:48 pm -
1 stop5h 20m
Tue 12/15:09 pm -
1 stop6h 29m
Deal found 10/21![Delta logo]()
$342
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:05 am -
2 stops7h 09m
Tue 12/16:00 pm -
1 stop4h 25m
Deal found 10/21![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:45 am -
1 stop4h 17m
Tue 12/15:41 pm -
1 stop3h 58m
Deal found 10/21![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:58 pm -
1 stop6h 02m
Tue 12/15:30 pm -
2 stops7h 49m
Deal found 10/21![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
1 stop4h 14m
Wed 12/26:10 am -
2 stops7h 29m
Deal found 10/22![United Airlines logo]()
$347
One-way flights from Des Moines to PittsburghSearch for one-way flight options from Des Moines to Pittsburgh. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
Search for one-way flight options from Des Moines to Pittsburgh. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:55 am -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$134
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:05 am -
2 stops7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$139
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/218:00 am -
3 stops14h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$195
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:48 pm -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:45 pm -
1 stop21h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Allegiant Air logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
3 stops45h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:42 pm -
2 stops25h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:26 pm -
3 stops27h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$339
Find flight deals from Des Moines to Pittsburgh
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Pittsburgh (PIT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $267 (Delta) |
One-way from | $134 (Southwest) |
Popular in | June |
Cheapest in | January |
Average price | $393 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
Use the filters below to find and compare flights from Des Moines to Pittsburgh that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Thu 1/21
6:55 am-4:05 pm
1 stop8h 10m
Pittsburgh
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$134
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Wed 11/25
9:55 am-4:55 pm
1 stop6h 00m
Pittsburgh
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$134
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Thu 11/26
6:05 am-2:14 pm
2 stops7h 09m
Pittsburgh
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$139
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Thu 1/21
8:00 am-11:14 pm
3 stops14h 14m
Pittsburgh
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
Quickest round-trip
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Thu 11/26
2:48 pm-9:08 pm
1 stop5h 20m
Pittsburgh
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$209
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Wed 1/6
10:55 am-4:17 pm
1 stop4h 22m
Pittsburgh
Wed 1/20
2:05 pm-4:50 pm
1 stop3h 45m
$267
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Mon 1/4
5:15 pm-12:19 am
1 stop6h 04m
Pittsburgh
Tue 1/19
12:43 pm-3:57 pm
1 stop4h 14m
$267
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Sat 12/12
5:29 pm-10:57 pm
1 stop4h 28m
Pittsburgh
Mon 12/14
11:17 am-4:11 pm
1 stop5h 54m
$267
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Sat 12/12
5:20 am-10:05 am
1 stop3h 45m
Pittsburgh
Mon 12/14
4:00 pm-10:05 pm
2 stops7h 05m
$272
Des MoinesPittsburgh
DSM Des Moines - PIT Pittsburgh
DSMPIT
Des Moines
Sun 12/13
6:40 am-4:15 pm
1 stop8h 35m
Pittsburgh
Tue 12/15
8:25 am-11:25 am
1 stop4h 00m
$278
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Pittsburgh
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Pittsburgh in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Pittsburgh flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Pittsburgh flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Pittsburgh flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Pittsburgh flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Pittsburgh flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Pittsburgh
Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Des Moines with our price prediction graph.
DSM-PIT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Pittsburgh
What is the cheapest month to book a flight from Des Moines to Pittsburgh?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Pittsburgh (average of $341). Flying from Des Moines to Pittsburgh in June is currently the most expensive (average of $656). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Pittsburgh?
Airfare is below average for this route at the moment.
Des Moines to Pittsburgh flights typically cost between $366 and $459 in January.The cheapest round-trip price found within the last 5 days was $267 on Delta (Jan 4-Jan 19).
Reviews of airlines servicing Pittsburgh
Get insights into the airlines that provide service to Pittsburgh. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Pittsburgh. Reviews last updated October 23, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Pittsburgh. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Boarding
8.1
Crew
8.6
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Pittsburgh?
Book flights to Pittsburgh if you plan to visit one of these locationsMonroeville
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Des Moines and Pittsburgh flights
Browse other Des Moines and Pittsburgh flight options. Last updated on October 23, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 23, 2026.
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Explore flights to Pittsburgh departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Des Moines to Pittsburgh
Discover the top 4 airlines that operate flights from Des Moines to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$272 | Average$446 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$515 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$314 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$316 | Average$386 | FlexibilityNo cancel fee | On-time69% |