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$159+ Cheap flights from Des Moines to Pittsburgh (DSM - PIT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PIT
Apr 7 — Apr 141
Tue 4/7
Tue 4/14
1 adult, Economy
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Cheap flight deals from Des Moines to Pittsburgh

Cheapest flights from Des Moines to Pittsburgh
Explore the most affordable flight options available from Des Moines to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.

This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:20 am
DSM
-
PIT
1 stop4h 05m
Southwest
Wed 4/87:10 pm
PIT
-
DSM
1 stop4h 00m
Southwest
Deal found 3/3$297
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:20 am
DSM
-
PIT
2 stops6h 38m
United Airlines
Wed 4/86:10 am
PIT
-
DSM
2 stops7h 19m
United Airlines
Deal found 3/3$307
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:35 am
DSM
-
PIT
2 stops7h 35m
Southwest
Tue 5/57:10 pm
PIT
-
DSM
1 stop4h 00m
Southwest
Deal found 3/5$312
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/41:37 pm
DSM
-
PIT
1 stop9h 34m
American Airlines
Sat 4/119:19 am
PIT
-
DSM
1 stop15h 30m
American Airlines
Deal found 3/7$315
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:01 pm
DSM
-
PIT
1 stop5h 53m
American Airlines
Tue 4/282:53 pm
PIT
-
DSM
1 stop7h 22m
American Airlines
Deal found 3/7$316
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:35 am
DSM
-
PIT
1 stop3h 30m
Southwest
Thu 4/91:35 pm
PIT
-
DSM
2 stops9h 20m
Southwest
Deal found 3/3$322
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:25 pm
DSM
-
PIT
1 stop6h 24m
Delta
Mon 4/66:30 am
PIT
-
DSM
1 stop4h 16m
Delta
Deal found 3/5$327
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/43:21 pm
DSM
-
PIT
1 stop4h 37m
United Airlines
Sat 4/118:54 am
PIT
-
DSM
2 stops8h 21m
United Airlines
Deal found 3/6$332
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:09 am
DSM
-
PIT
1 stop6h 23m
American Airlines
Mon 4/276:12 am
PIT
-
DSM
1 stop5h 14m
American Airlines
Deal found 3/7$335
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:40 am
DSM
-
PIT
1 stop7h 45m
Southwest
Tue 3/317:20 pm
PIT
-
DSM
1 stop3h 45m
Southwest
Deal found 3/4$337

Find flight deals from Des Moines to Pittsburgh

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Pittsburgh (PIT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(Southwest)

One-way from

$159
(Delta)

Popular in

March

Cheapest in

May

Average price

$683
Provider with most accurate pricing for Des Moines-Pittsburgh flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Pittsburgh flights.
Search Deals
From Des Moines to Pittsburgh
Search Deals
One-way flight from Des Moines to Pittsburgh
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Des Moines to Pittsburgh that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Thu 4/2

5:35 am-10:05 am

1 stop3h 30m

Pittsburgh

Thu 4/9

8:00 pm-11:05 pm

1 stop4h 05m

$317

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 5/2

2:10 pm-11:45 pm

1 stop8h 35m

Pittsburgh

Tue 5/5

7:10 pm-10:10 pm

1 stop4h 00m

$317

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 4/4

12:29 pm-5:20 pm

1 stop3h 51m

Pittsburgh

Sat 4/11

5:25 pm-9:10 pm

1 stop4h 45m

$327

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Tue 4/21

5:30 am-12:55 pm

2 stops6h 25m

Pittsburgh

Tue 4/28

6:50 am-2:05 pm

2 stops8h 15m

$327

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 4/4

3:21 pm-8:58 pm

1 stop4h 37m

Pittsburgh

Sat 4/11

8:54 am-4:15 pm

2 stops8h 21m

$332

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Wed 4/22

5:30 am-10:15 am

1 stop3h 45m

Pittsburgh

Sun 4/26

8:15 pm-11:20 pm

1 stop4h 05m

$332

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Mon 3/30

4:25 pm-11:49 pm

1 stop6h 24m

Pittsburgh

Mon 4/6

6:30 am-9:46 am

1 stop4h 16m

$337

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Tue 3/24

6:40 am-3:25 pm

1 stop7h 45m

Pittsburgh

Tue 3/31

7:20 pm-10:05 pm

1 stop3h 45m

$337

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Thu 7/2

6:20 am-11:11 am

1 stop3h 51m

Pittsburgh

Mon 7/6

6:00 am-10:14 am

1 stop5h 14m

$377

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Tue 5/5

5:00 am-2:02 pm

2 stops8h 02m

Pittsburgh

Wed 5/6

7:05 am-4:15 pm

2 stops10h 10m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Des Moines to Pittsburgh

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Pittsburgh in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Pittsburgh flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Pittsburgh flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Pittsburgh flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Pittsburgh flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Pittsburgh flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Pittsburgh

Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Pittsburgh

What is the cheapest month to book a flight from Des Moines to Pittsburgh?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Pittsburgh (average of $198). Flying from Des Moines to Pittsburgh in March is currently the most expensive (average of $410). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Pittsburgh

Get insights into the airlines that provide service to Pittsburgh. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Pittsburgh. Reviews last updated March 8, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Pittsburgh. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,269 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,269 reviews
Delta
7.9
Good
8,269 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,405 reviews
Delta
7.9
Good
8,269 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,397 reviews
Delta
7.9
Good
8,269 reviews

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Pittsburgh?

    Southwest, Delta, and United Airlines can get you from Des Moines to Pittsburgh in just under 3h 30m. Your travel time can differ by up to 1h 07m. Des Moines and Pittsburgh are separated by a distance of 702 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Pittsburgh round-trip?

    Our cheapest airline available from Des Moines to Pittsburgh is American Airlines. Our recent data shows that you can find tickets from as low as $208 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $216 and $271 round-trip. American Airlines is currently priced 44% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Pittsburgh one-way?

    The cheapest airlines for a one-way flight from Des Moines to Pittsburgh are American Airlines ($108), Delta ($128), and United Airlines ($155).

  • Can I find deals for flights from Des Moines to Pittsburgh that include hotel bookings?

    Yes. In addition to deals on Des Moines to Pittsburgh flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Pittsburgh?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Pittsburgh.

  • Can I find deals for business class flights from Des Moines to Pittsburgh?

    Yes. Cheapflights offers flight deals from Des Moines to Pittsburgh by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Pittsburgh?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Pittsburgh (average of $198). Flying from Des Moines to Pittsburgh in March is currently the most expensive (average of $410). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Pittsburgh?

Book flights to Pittsburgh if you plan to visit one of these locations
Mars
Chester
Steubenville
Washington
Monroeville
Wexford
Belle Vernon

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Top 3 airlines flying from Des Moines to Pittsburgh

Discover the top 3 airlines that operate flights from Des Moines to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$301FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$362FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$271Average$367FlexibilityNo cancel feeOn-time69%

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