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$105+ Cheap flights from Des Moines to Pittsburgh (DSM - PIT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PIT
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Des Moines to Pittsburgh

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Pittsburgh (PIT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$209
(American Airlines)

One-way from

$105
(American Airlines)

Popular in

March

Cheapest in

May

Average price

$394
From Des Moines to Pittsburgh
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One-way flight from Des Moines to Pittsburgh
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Highest demand for flights based on searches. 23% potential increase in price ($124 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Pittsburgh

Cheapest flights from Des Moines to Pittsburgh
Explore the most affordable flight options available from Des Moines to Pittsburgh. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:22 pmDSM - PIT
1 stop4h 37mAmerican Airlines
Tue 10/286:05 amPIT - DSM
1 stop5h 40mAmerican Airlines
Deal found 9/12$209
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - PIT
1 stop6h 17mDelta
Wed 10/2911:02 amPIT - DSM
1 stop3h 57mDelta
Deal found 9/12$217
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:07 amDSM - PIT
1 stop7h 02mAmerican Airlines
Fri 10/108:31 pmPIT - DSM
1 stop3h 52mAmerican Airlines
Deal found 9/12$255
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:30 amDSM - PIT
1 stop8h 04mAmerican Airlines
Tue 10/146:09 amPIT - DSM
1 stop12h 28mAmerican Airlines
Deal found 9/13$275
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:25 amDSM - PIT
2 stops11h 20mSouthwest
Tue 10/281:50 pmPIT - DSM
2 stops9h 00mSouthwest
Deal found 9/12$281
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:15 pmDSM - PIT
1 stop6h 17mDelta
Tue 10/286:00 pmPIT - DSM
1 stop3h 35mDelta
Deal found 9/13$287
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/285:49 pmDSM - PIT
2 stops38h 41mMultiple Airlines
Thu 10/23:50 pmPIT - DSM
1 stop24h 00mMultiple Airlines
Deal found 9/13$289
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:25 amDSM - PIT
2 stops13h 25mSouthwest
Tue 11/43:35 pmPIT - DSM
1 stop7h 00mSouthwest
Deal found 9/13$292
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:37 amDSM - PIT
1 stop9h 34mMultiple Airlines
Wed 10/16:30 amPIT - DSM
1 stop28h 21mMultiple Airlines
Deal found 9/13$295
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:30 amDSM - PIT
1 stop6h 12mAmerican Airlines
Mon 10/138:31 pmPIT - DSM
1 stop3h 52mAmerican Airlines
Deal found 9/14$297
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/88:00 amDSM - PIT
2 stops8h 56mUnited Airlines
Fri 10/105:56 pmPIT - DSM
1 stop4h 54mUnited Airlines
Deal found 9/12$305

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Pittsburgh that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Des Moines to Pittsburgh that are best for you.

Fly from

Des Moines

Fly to

Pittsburgh

Route

Depart

Return

Price

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 10/25

5:15 pm-12:32 am

1 stop6h 17m

Pittsburgh

Wed 10/29

11:02 am-1:59 pm

1 stop3h 57m

$217

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 10/11

7:30 am-4:34 pm

1 stop8h 04m

Pittsburgh

Tue 10/14

6:09 am-5:37 pm

1 stop12h 28m

$275

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 10/25

7:25 am-7:45 pm

2 stops11h 20m

Pittsburgh

Tue 10/28

1:50 pm-9:50 pm

2 stops9h 00m

$281

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 10/25

5:15 pm-12:32 am

1 stop6h 17m

Pittsburgh

Tue 10/28

6:00 pm-8:35 pm

1 stop3h 35m

$287

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 11/1

7:25 am-9:50 pm

2 stops13h 25m

Pittsburgh

Tue 11/4

3:35 pm-9:35 pm

1 stop7h 00m

$292

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 10/11

7:30 am-2:42 pm

1 stop6h 12m

Pittsburgh

Mon 10/13

8:31 pm-11:23 pm

1 stop3h 52m

$297

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 11/8

5:47 am-12:43 pm

1 stop5h 56m

Pittsburgh

Mon 11/10

6:00 am-10:20 am

1 stop5h 20m

$297

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Wed 10/8

9:00 am-5:04 pm

1 stop7h 04m

Pittsburgh

Fri 10/10

8:31 pm-11:23 pm

1 stop3h 52m

$302

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Sat 11/8

5:25 am-2:25 pm

1 stop8h 00m

Pittsburgh

Mon 11/10

5:15 pm-11:35 pm

2 stops7h 20m

$302

Des MoinesPittsburgh

DSM - PIT

DSMPIT

Des Moines

Wed 10/8

8:00 am-5:56 pm

2 stops8h 56m

Pittsburgh

Fri 10/10

5:56 pm-9:50 pm

1 stop4h 54m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 17 results
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Best time to book a flight from Des Moines to Pittsburgh

Have a flexible travel schedule? Discover the best time to fly to Pittsburgh from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Pittsburgh

What is the cheapest month to book a flight from Des Moines to Pittsburgh?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Pittsburgh (average of $262). Flying from Des Moines to Pittsburgh in November is currently the most expensive (average of $333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Pittsburgh

Get insights into the airlines that provide service to Pittsburgh. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Pittsburgh. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Pittsburgh. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Pittsburgh. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Pittsburgh?

    Delta, American Airlines, and Southwest can get you from Des Moines to Pittsburgh in just under 6h 17m. Your travel time can differ by up to 5h 03m. Des Moines and Pittsburgh are separated by a distance of 702 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Pittsburgh round-trip?

    Our cheapest airline available from Des Moines to Pittsburgh is American Airlines. Our recent data shows that you can find tickets from as low as $258 on this airline. Additional options worth looking into are United Airlines and Delta, starting at $271 and $271 round-trip. American Airlines is currently priced 35% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Pittsburgh that include hotel bookings?

    Yes. In addition to deals on Des Moines to Pittsburgh flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Pittsburgh?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Pittsburgh.

  • Can I find deals for business class flights from Des Moines to Pittsburgh?

    Yes. Cheapflights offers flight deals from Des Moines to Pittsburgh by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Pittsburgh?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Pittsburgh (average of $262). Flying from Des Moines to Pittsburgh in November is currently the most expensive (average of $333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Pittsburgh?

Book flights to Pittsburgh if you plan to visit one of these locations
Mars
Steubenville
Monroeville
Washington
Wexford
Belle Vernon

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Alternative routes for Des Moines to Pittsburgh

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Pittsburgh

Discover the top 3 airlines that operate flights from Des Moines to Pittsburgh. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$346FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$534FlexibilityNo cancel feeOn-time69%
DeltaCheapest$271Average$344FlexibilityNo cancel feeOn-timeN/A

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